Project measure / variable:   Peters4   MCV_M12

ID, description, units MPD:24374   MCV_M12   mean RBC corpuscular volume (MCV)   [fL]  at age 12mo  
Data set, strains Peters4   inbred   30 strains     sex: both     age: 52wks
Procedure complete blood count
Ontology mappings

  STRAIN COMPARISON PLOT
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Peters4 - mean RBC corpuscular volume (MCV) at age 12mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested30 strains30 strains
Mean of the strain means47.3   fL 47.3   fL
Median of the strain means47.6   fL 47.9   fL
SD of the strain means± 2.41 ± 2.79
Coefficient of variation (CV)0.0509 0.0589
Min–max range of strain means42.1   –   52.0   fL 42.3   –   52.5   fL
Mean sample size per strain7.8   mice 7.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 3.3812 3.3812 1.3328 0.249
strain 29 2462.879 84.9269 33.4756 < 0.0001
sex:strain 29 444.4654 15.3264 6.0412 < 0.0001
Residuals 395 1002.1051 2.537


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 47.6 1.85   8 0.652 0.0388 43.7, 50.1 0.13
129S1/SvImJ m 46.4 0.825   7 0.312 0.0178 45.3, 47.5 -0.32
A/J f 46.6 1.23   7 0.466 0.0265 44.9, 48.6 -0.28
A/J m 46.9 1.99   6 0.813 0.0425 44.9, 50.6 -0.14
BALB/cByJ f 45.4 0.489   7 0.185 0.0108 44.8, 46.1 -0.78
BALB/cByJ m 43.1 1.1   7 0.416 0.0255 42.1, 44.8 -1.51
BTBR T+ Itpr3tf/J f 48.5 0.684   8 0.242 0.0141 47.5, 49.3 0.51
BTBR T+ Itpr3tf/J m 48.0 0.972   8 0.344 0.0202 46.3, 49.2 0.25
BUB/BnJ f 46.7 1.4   7 0.529 0.0299 44.9, 48.7 -0.24
BUB/BnJ m 49.1 2.22   6 0.906 0.0452 45.4, 51.0 0.65
C3H/HeJ f 47.6 0.555   8 0.196 0.0117 47.0, 48.7 0.13
C3H/HeJ m 48.1 1.72   8 0.609 0.0357 45.3, 50.2 0.29
C57BL/10J f 44.1 1.05   9 0.348 0.0237 42.7, 45.9 -1.32
C57BL/10J m 48.0 1.08   8 0.382 0.0225 46.5, 49.4 0.25
C57BL/6J f 47.2 1.0   7 0.378 0.0212 45.3, 48.6 -0.03
C57BL/6J m 47.7 0.843   6 0.344 0.0177 46.6, 48.8 0.15
C57BLKS/J f 44.7 1.21   8 0.427 0.027 42.9, 46.0 -1.07
C57BLKS/J m 45.5 0.827   8 0.292 0.0182 44.1, 46.6 -0.64
C57BR/cdJ f 46.9 2.93   8 1.04 0.0624 40.7, 50.0 -0.16
C57BR/cdJ m 47.1 2.63   8 0.929 0.0558 41.5, 49.4 -0.07
C57L/J f 52.0 1.65   8 0.584 0.0318 49.3, 54.3 1.96
C57L/J m 51.9 1.57   8 0.557 0.0303 49.2, 53.6 1.65
CAST/EiJ f 42.5 1.23   8 0.436 0.029 40.8, 44.3 -1.99
CAST/EiJ m 45.0 2.62   6 1.07 0.0581 43.1, 50.2 -0.82
CBA/J f 48.8 0.794   8 0.281 0.0163 47.8, 50.4 0.63
CBA/J m 48.4 2.13   7 0.807 0.0441 45.5, 52.5 0.4
DBA/2J f 42.1 0.885   8 0.313 0.021 40.8, 43.2 -2.15
DBA/2J m 42.4 2.04   7 0.771 0.0481 39.4, 46.0 -1.76
FVB/NJ f 47.7 1.29   8 0.455 0.027 46.1, 49.8 0.17
FVB/NJ m 48.1 1.41   8 0.498 0.0293 46.7, 50.5 0.29
KK/HlJ f 46.8 1.46   7 0.551 0.0311 44.1, 48.6 -0.2
KK/HlJ m 47.6 1.63   11 0.491 0.0342 44.9, 49.8 0.11
LP/J f 48.2 0.653   8 0.231 0.0136 46.8, 48.8 0.38
LP/J m 49.6 3.17   7 1.2 0.0638 46.4, 56.0 0.83
MRL/MpJ f 47.9 2.01   8 0.71 0.042 44.7, 51.4 0.26
MRL/MpJ m 48.1 0.9   8 0.318 0.0187 47.1, 49.7 0.29
NOD.B10Sn-H2b/J f 49.3 0.701   8 0.248 0.0142 47.8, 50.2 0.84
NOD.B10Sn-H2b/J m 49.7 0.457   8 0.161 0.00918 49.0, 50.5 0.86
NON/ShiLtJ f 48.5 1.44   9 0.48 0.0296 46.4, 50.4 0.51
NON/ShiLtJ m 51.9 1.79   7 0.676 0.0345 48.8, 54.4 1.65
NZO/HlLtJ f 47.8 1.13   6 0.463 0.0237 46.2, 49.5 0.21
NZO/HlLtJ m 42.3 4.57   6 1.86 0.108 34.7, 48.5 -1.79
NZW/LacJ f 51.2 0.434   8 0.154 0.00848 50.6, 51.8 1.63
NZW/LacJ m 47.1 0.87   8 0.308 0.0185 45.9, 48.4 -0.07
P/J f 45.6 1.02   7 0.387 0.0225 44.6, 47.4 -0.7
P/J m 42.9 0.608   3 0.351 0.0142 42.2, 43.3 -1.58
PL/J f 46.3 1.26   7 0.477 0.0272 44.6, 48.5 -0.41
PL/J m 45.0 2.37   10 0.75 0.0526 42.2, 49.6 -0.82
PWD/PhJ f 46.8 1.04   8 0.366 0.0221 45.5, 48.2 -0.2
PWD/PhJ m 43.2 1.27   8 0.45 0.0294 40.7, 44.5 -1.47
RIIIS/J f 49.2 0.914   8 0.323 0.0186 47.8, 50.6 0.8
RIIIS/J m 48.6 0.604   7 0.228 0.0124 47.8, 49.8 0.47
SJL/J f 48.1 1.27   7 0.479 0.0263 46.7, 50.5 0.34
SJL/J m 49.1 3.25   8 1.15 0.0662 46.3, 56.8 0.65
SM/J f 49.4 1.44   8 0.51 0.0292 46.9, 51.4 0.88
SM/J m 50.4 2.1   8 0.743 0.0417 49.0, 55.5 1.12
SWR/J f 51.7 0.53   7 0.201 0.0103 51.1, 52.6 1.83
SWR/J m 52.5 1.0   8 0.354 0.0191 50.9, 54.2 1.87
WSB/EiJ f 43.3 1.53   9 0.509 0.0353 41.2, 45.3 -1.65
WSB/EiJ m 45.1 0.735   8 0.26 0.0163 44.1, 46.4 -0.79


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 47.575 0.5631 48.6821 46.4679
129S1/SvImJ m 46.4 0.602 47.5836 45.2164
A/J f 46.5571 0.602 47.7407 45.3736
A/J m 46.8667 0.6503 48.1451 45.5883
BALB/cByJ f 45.4286 0.602 46.6121 44.245
BALB/cByJ m 43.0571 0.602 44.2407 41.8736
BTBR T+ Itpr3tf/J f 48.4625 0.5631 49.5696 47.3554
BTBR T+ Itpr3tf/J m 48.0375 0.5631 49.1446 46.9304
BUB/BnJ f 46.7429 0.602 47.9264 45.5593
BUB/BnJ m 49.0833 0.6503 50.3617 47.8049
C3H/HeJ f 47.6 0.5631 48.7071 46.4929
C3H/HeJ m 48.15 0.5631 49.2571 47.0429
C57BL/10J f 44.1333 0.5309 45.1771 43.0895
C57BL/10J m 48.0125 0.5631 49.1196 46.9054
C57BL/6J f 47.2286 0.602 48.4121 46.045
C57BL/6J m 47.7333 0.6503 49.0117 46.4549
C57BLKS/J f 44.6875 0.5631 45.7946 43.5804
C57BLKS/J m 45.5125 0.5631 46.6196 44.4054
C57BR/cdJ f 46.95 0.5631 48.0571 45.8429
C57BR/cdJ m 47.05 0.5631 48.1571 45.9429
C57L/J f 51.9875 0.5631 53.0946 50.8804
C57L/J m 51.9125 0.5631 53.0196 50.8054
CAST/EiJ f 42.55 0.5631 43.6571 41.4429
CAST/EiJ m 45.0333 0.6503 46.3117 43.7549
CBA/J f 48.775 0.5631 49.8821 47.6679
CBA/J m 48.3857 0.602 49.5693 47.2022
DBA/2J f 42.1125 0.5631 43.2196 41.0054
DBA/2J m 42.3857 0.602 43.5693 41.2022
FVB/NJ f 47.7125 0.5631 48.8196 46.6054
FVB/NJ m 48.1125 0.5631 49.2196 47.0054
KK/HlJ f 46.8143 0.602 47.9978 45.6307
KK/HlJ m 47.5818 0.4802 48.526 46.6377
LP/J f 48.1875 0.5631 49.2946 47.0804
LP/J m 49.6143 0.602 50.7978 48.4307
MRL/MpJ f 47.85 0.5631 48.9571 46.7429
MRL/MpJ m 48.125 0.5631 49.2321 47.0179
NOD.B10Sn-H2b/J f 49.275 0.5631 50.3821 48.1679
NOD.B10Sn-H2b/J m 49.7375 0.5631 50.8446 48.6304
NON/ShiLtJ f 48.5333 0.5309 49.5771 47.4895
NON/ShiLtJ m 51.8714 0.602 53.055 50.6879
NZO/HlLtJ f 47.8167 0.6503 49.0951 46.5383
NZO/HlLtJ m 42.2667 0.6503 43.5451 40.9883
NZW/LacJ f 51.2 0.5631 52.3071 50.0929
NZW/LacJ m 47.1375 0.5631 48.2446 46.0304
P/J f 45.5571 0.602 46.7407 44.3736
P/J m 42.9 0.9196 44.7079 41.0921
PL/J f 46.3429 0.602 47.5264 45.1593
PL/J m 45.03 0.5037 46.0202 44.0398
PWD/PhJ f 46.8125 0.5631 47.9196 45.7054
PWD/PhJ m 43.25 0.5631 44.3571 42.1429
RIIIS/J f 49.1875 0.5631 50.2946 48.0804
RIIIS/J m 48.6143 0.602 49.7978 47.4307
SJL/J f 48.1286 0.602 49.3121 46.945
SJL/J m 49.1125 0.5631 50.2196 48.0054
SM/J f 49.3625 0.5631 50.4696 48.2554
SM/J m 50.4125 0.5631 51.5196 49.3054
SWR/J f 51.6857 0.602 52.8693 50.5022
SWR/J m 52.525 0.5631 53.6321 51.4179
WSB/EiJ f 43.3444 0.5309 44.3882 42.3006
WSB/EiJ m 45.0625 0.5631 46.1696 43.9554


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 46.9875 0.4122 47.7978 46.1772
A/J both 46.7119 0.4431 47.583 45.8408
BALB/cByJ both 44.2429 0.4257 45.0798 43.406
BTBR T+ Itpr3tf/J both 48.25 0.3982 49.0329 47.4671
BUB/BnJ both 47.9131 0.4431 48.7842 47.042
C3H/HeJ both 47.875 0.3982 48.6579 47.0921
C57BL/10J both 46.0729 0.387 46.8337 45.3121
C57BL/6J both 47.481 0.4431 48.352 46.6099
C57BLKS/J both 45.1 0.3982 45.8829 44.3171
C57BR/cdJ both 47.0 0.3982 47.7829 46.2171
C57L/J both 51.95 0.3982 52.7329 51.1671
CAST/EiJ both 43.7917 0.4301 44.6372 42.9461
CBA/J both 48.5804 0.4122 49.3907 47.77
DBA/2J both 42.2491 0.4122 43.0594 41.4388
FVB/NJ both 47.9125 0.3982 48.6954 47.1296
KK/HlJ both 47.1981 0.3851 47.9551 46.441
LP/J both 48.9009 0.4122 49.7112 48.0906
MRL/MpJ both 47.9875 0.3982 48.7704 47.2046
NOD.B10Sn-H2b/J both 49.5063 0.3982 50.2891 48.7234
NON/ShiLtJ both 50.2024 0.4013 50.9914 49.4133
NZO/HlLtJ both 45.0417 0.4598 45.9456 44.1377
NZW/LacJ both 49.1688 0.3982 49.9516 48.3859
P/J both 44.2286 0.5496 45.309 43.1481
PL/J both 45.6864 0.3925 46.458 44.9148
PWD/PhJ both 45.0313 0.3982 45.8141 44.2484
RIIIS/J both 48.9009 0.4122 49.7112 48.0906
SJL/J both 48.6205 0.4122 49.4309 47.8102
SM/J both 49.8875 0.3982 50.6704 49.1046
SWR/J both 52.1054 0.4122 52.9157 51.295
WSB/EiJ both 44.2035 0.387 44.9643 43.4427




  GWAS USING LINEAR MIXED MODELS