Project measure / variable:   Peters4   pctEOS_M18

ID, description, units MPD:24347   pctEOS_M18   eosinophil differential (EOS; percentage of total WBC)   [%]  at age 18mo  
Data set, strains Peters4   inbred   30 strains     sex: both     age: 78wks
Procedure complete blood count
Ontology mappings

  STRAIN COMPARISON PLOT
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Peters4 - eosinophil differential (EOS; percentage of total WBC) at age 18mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested28 strains29 strains
Mean of the strain means3.92   % 3.09   %
Median of the strain means2.69   % 2.74   %
SD of the strain means± 3.07 ± 1.24
Coefficient of variation (CV)0.783 0.403
Min–max range of strain means1.53   –   16.4   % 0.450   –   5.78   %
Mean sample size per strain7.0   mice 7.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 93.5287 93.5287 13.5532 0.0003
strain 26 1577.4171 60.6699 8.7916 < 0.0001
sex:strain 26 468.1152 18.0044 2.609 < 0.0001
Residuals 334 2304.8852 6.9009


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 5.49 1.88   8 0.665 0.343 3.3, 8.4 0.51
129S1/SvImJ m 2.16 2.11   7 0.796 0.977 1.0, 6.9 -0.75
A/J f 6.47 3.71   7 1.4 0.574 2.9, 11.7 0.83
A/J m 2.9 1.84   15 0.475 0.634 1.1, 8.1 -0.15
BALB/cByJ f 6.53 5.47   8 1.93 0.838 2.6, 15.5 0.85
BALB/cByJ m 4.34 1.54   7 0.583 0.355 2.9, 7.1 1.01
BTBR T+ Itpr3tf/J f 1.74 0.695   8 0.246 0.4 0.9, 3.2 -0.71
BTBR T+ Itpr3tf/J m 1.6 0.626   6 0.256 0.391 0.9, 2.5 -1.2
BUB/BnJ f 2.34 0.873   5 0.391 0.373 1.6, 3.7 -0.51
BUB/BnJ m 2.67 1.42   6 0.581 0.534 0.9, 4.7 -0.34
C3H/HeJ f 3.56 1.54   7 0.581 0.432 1.9, 6.6 -0.12
C3H/HeJ m 2.1 0.739   8 0.261 0.352 0.8, 3.1 -0.79
C57BL/10J f 2.81 1.5   7 0.566 0.532 -0.36
C57BL/10J m 2.76 1.06   13 0.294 0.384 1.0, 4.4 -0.26
C57BL/6J f 2.24 0.714   7 0.27 0.318 1.1, 3.4 -0.55
C57BL/6J m 2.56 1.17   7 0.441 0.456 -0.42
C57BLKS/J m 4.61 1.17   16 0.292 0.254 3.2, 7.2 1.22
C57BR/cdJ f 2.8 0.756   8 0.267 0.27 1.3, 4.0 -0.36
C57BR/cdJ m 2.66 0.602   8 0.213 0.226 2.1, 3.7 -0.34
C57L/J f 2.2 1.01   7 0.382 0.459 1.4, 3.8 -0.56
C57L/J m 2.73 0.959   7 0.362 0.351 1.7, 4.4 -0.29
CAST/EiJ f 2.85 1.89   8 0.669 0.664 1.2, 7.0 -0.35
CBA/J f 1.95 0.495   2   0.35 0.254 1.6, 2.3 -0.64
CBA/J m 1.56 0.961   5 0.43 0.616 0.5, 3.0 -1.23
DBA/2J f 1.88 0.922   6 0.376 0.489 0.9, 3.3 -0.66
DBA/2J m 2.9 1.1   6 0.447 0.378 1.8, 4.2 -0.15
FVB/NJ f 1.73 0.706   7 0.267 0.409 1.2, 3.1 -0.71
FVB/NJ m 2.33 1.15   12 0.333 0.495 0.4, 4.2 -0.61
KK/HlJ f 2.42 0.788   6 0.322 0.326 1.6, 3.7 -0.49
KK/HlJ m 3.43 1.21   7 0.459 0.354 1.5, 4.9 0.28
LP/J m 2.59 0.653   8 0.231 0.253 1.4, 3.4 -0.4
MRL/MpJ f 2.59 0.917   7 0.347 0.355 1.3, 3.8 -0.43
MRL/MpJ m 3.67 0.754   8 0.266 0.205 2.4, 5.1 0.47
NOD.B10Sn-H2b/J f 1.53 0.407   7 0.154 0.266 0.8, 2.0 -0.78
NOD.B10Sn-H2b/J m 1.87 0.461   7 0.174 0.246 1.1, 2.5 -0.98
NON/ShiLtJ f 4.74 2.81   5 1.26 0.593 2.2, 7.8 0.27
NON/ShiLtJ m 4.23 4.09   7 1.55 0.968 0.9, 12.9 0.92
NZO/HlLtJ f 1.68 0.611   10 0.193 0.363 0.8, 2.7 -0.73
NZO/HlLtJ m 3.2 1.98   2   1.4 0.619 1.8, 4.6 0.09
NZW/LacJ f 2.27 1.82   7 0.687 0.8 0.1, 5.2 -0.54
NZW/LacJ m 0.45 0.394   6 0.161 0.875 0.1, 1.2 -2.12
P/J f 4.86 3.27   7 1.24 0.674 1.3, 10.5 0.31
P/J m 2.24 2.09   5 0.937 0.935 0.7, 5.8 -0.68
PL/J f 6.5 4.14   8 1.46 0.637 2.0, 15.2 0.84
PL/J m 5.04 1.8   8 0.638 0.358 1.9, 8.1 1.57
PWD/PhJ f 6.12 4.61   6 1.88 0.754 3.5, 15.4 0.72
PWD/PhJ m 4.2 2.78   7 1.05 0.662 1.4, 8.8 0.89
RIIIS/J f 1.84 1.17   8 0.413 0.636 0.7, 4.3 -0.68
RIIIS/J m 2.42 0.772   8 0.273 0.318 1.5, 4.0 -0.54
SJL/J f 16.4 11.5   7 4.34 0.701 2.2, 31.9 4.07
SJL/J m 5.78 2.7   4 1.35 0.468 3.8, 9.7 2.17
SM/J f 2.07 0.468   6 0.191 0.226 1.6, 2.6 -0.6
SM/J m 2.74 1.45   9 0.483 0.528 1.3, 5.4 -0.28
SWR/J f 4.39 3.02   7 1.14 0.688 1.3, 10.1 0.15
SWR/J m 5.55 3.78   8 1.34 0.682 1.4, 11.5 1.98
WSB/EiJ f 7.7 5.45   8 1.93 0.707 4.3, 20.2 1.23
WSB/EiJ m 4.26 0.873   9 0.291 0.205 2.5, 5.4 0.94


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 5.4875 0.9288 7.3145 3.6605
129S1/SvImJ m 2.1571 0.9929 4.1103 0.204
A/J f 6.4714 0.9929 8.4245 4.5183
A/J m 2.9 0.6783 4.2342 1.5658
BALB/cByJ f 6.525 0.9288 8.352 4.698
BALB/cByJ m 4.3429 0.9929 6.296 2.3897
BTBR T+ Itpr3tf/J f 1.7375 0.9288 3.5645 0.0
BTBR T+ Itpr3tf/J m 1.6 1.0724 3.7096 0.0
BUB/BnJ f 2.34 1.1748 4.651 0.029
BUB/BnJ m 2.6667 1.0724 4.7763 0.5571
C3H/HeJ f 3.5571 0.9929 5.5103 1.604
C3H/HeJ m 2.1 0.9288 3.927 0.273
C57BL/10J f 2.8143 0.9929 4.7674 0.8612
C57BL/10J m 2.7615 0.7286 4.1947 1.3283
C57BL/6J f 2.2429 0.9929 4.196 0.2897
C57BL/6J m 2.5571 0.9929 4.5103 0.604
C57BR/cdJ f 2.8 0.9288 4.627 0.973
C57BR/cdJ m 2.6625 0.9288 4.4895 0.8355
C57L/J f 2.2 0.9929 4.1531 0.2469
C57L/J m 2.7286 0.9929 4.6817 0.7755
CBA/J f 1.95 1.8575 5.6039 0.0
CBA/J m 1.56 1.1748 3.871 0.0
DBA/2J f 1.8833 1.0724 3.9929 0.0
DBA/2J m 2.9 1.0724 5.0096 0.7904
FVB/NJ f 1.7286 0.9929 3.6817 0.0
FVB/NJ m 2.3333 0.7583 3.825 0.8416
KK/HlJ f 2.4167 1.0724 4.5263 0.3071
KK/HlJ m 3.4286 0.9929 5.3817 1.4755
MRL/MpJ f 2.5857 0.9929 4.5388 0.6326
MRL/MpJ m 3.675 0.9288 5.502 1.848
NOD.B10Sn-H2b/J f 1.5286 0.9929 3.4817 0.0
NOD.B10Sn-H2b/J m 1.8714 0.9929 3.8245 0.0
NON/ShiLtJ f 4.74 1.1748 7.051 2.429
NON/ShiLtJ m 4.2286 0.9929 6.1817 2.2755
NZO/HlLtJ f 1.68 0.8307 3.3141 0.0459
NZO/HlLtJ m 3.2 1.8575 6.8539 0.0
NZW/LacJ f 2.2714 0.9929 4.2245 0.3183
NZW/LacJ m 0.45 1.0724 2.5596 0.0
P/J f 4.8571 0.9929 6.8103 2.904
P/J m 2.24 1.1748 4.551 0.0
PL/J f 6.5 0.9288 8.327 4.673
PL/J m 5.0375 0.9288 6.8645 3.2105
PWD/PhJ f 6.1167 1.0724 8.2263 4.0071
PWD/PhJ m 4.2 0.9929 6.1531 2.2469
RIIIS/J f 1.8375 0.9288 3.6645 0.0105
RIIIS/J m 2.425 0.9288 4.252 0.598
SJL/J f 16.3857 0.9929 18.3388 14.4326
SJL/J m 5.775 1.3135 8.3587 3.1913
SM/J f 2.0667 1.0724 4.1763 0.0
SM/J m 2.7444 0.8756 4.4669 1.022
SWR/J f 4.3857 0.9929 6.3388 2.4326
SWR/J m 5.55 0.9288 7.377 3.723
WSB/EiJ f 7.7 0.9288 9.527 5.873
WSB/EiJ m 4.2556 0.8756 5.978 2.5331


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 3.8223 0.6798 5.1595 2.4851
A/J both 4.6857 0.6012 5.8684 3.503
BALB/cByJ both 5.4339 0.6798 6.7711 4.0967
BTBR T+ Itpr3tf/J both 1.6687 0.7094 3.0641 0.2734
BUB/BnJ both 2.5033 0.7953 4.0679 0.9388
C3H/HeJ both 2.8286 0.6798 4.1658 1.4914
C57BL/10J both 2.7879 0.6158 3.9992 1.5766
C57BL/6J both 2.4 0.7021 3.7811 1.0189
C57BR/cdJ both 2.7312 0.6567 4.0231 1.4394
C57L/J both 2.4643 0.7021 3.8453 1.0832
CBA/J both 1.755 1.0989 3.9167 0.0
DBA/2J both 2.3917 0.7583 3.8834 0.9
FVB/NJ both 2.031 0.6247 3.2598 0.8021
KK/HlJ both 2.9226 0.7307 4.3601 1.4852
MRL/MpJ both 3.1304 0.6798 4.4676 1.7932
NOD.B10Sn-H2b/J both 1.7 0.7021 3.0811 0.3189
NON/ShiLtJ both 4.4843 0.7691 5.9972 2.9714
NZO/HlLtJ both 2.44 1.0174 4.4413 0.4387
NZW/LacJ both 1.3607 0.7307 2.7982 0.0
P/J both 3.5486 0.7691 5.0614 2.0357
PL/J both 5.7688 0.6567 7.0606 4.4769
PWD/PhJ both 5.1583 0.7307 6.5958 3.7209
RIIIS/J both 2.1313 0.6567 3.4231 0.8394
SJL/J both 11.0804 0.8233 12.6998 9.4609
SM/J both 2.4056 0.6923 3.7673 1.0438
SWR/J both 4.9679 0.6798 6.3051 3.6307
WSB/EiJ both 5.9778 0.6382 7.2332 4.7223




  GWAS USING LINEAR MIXED MODELS