Project measure / variable:   Peters4   pctNEUT_M18

ID, description, units MPD:24335   pctNEUT_M18   neutrophil differential (NEUT; percentage of total WBC)   [%]  at age 18mo  
Data set, strains Peters4   inbred   30 strains     sex: both     age: 78wks
Procedure complete blood count
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Peters4 - neutrophil differential (NEUT; percentage of total WBC) at age 18mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested28 strains29 strains
Mean of the strain means26.2   % 28.9   %
Median of the strain means23.9   % 29.5   %
SD of the strain means± 10.4 ± 12.7
Coefficient of variation (CV)0.397 0.438
Min–max range of strain means9.33   –   53.1   % 10.3   –   50.1   %
Mean sample size per strain7.0   mice 7.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1121.991 1121.991 9.8461 0.0019
strain 26 41546.9752 1597.9606 14.023 < 0.0001
sex:strain 26 9669.2987 371.8961 3.2636 < 0.0001
Residuals 334 38060.2572 113.9529


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 24.1 8.02   8 2.84 0.333 10.8, 33.7 -0.2
129S1/SvImJ m 50.1 11.1   7 4.2 0.222 33.5, 67.0 1.68
A/J f 29.7 8.43   7 3.19 0.284 23.3, 48.3 0.34
A/J m 36.2 15.6   15 4.03 0.432 17.5, 71.1 0.58
BALB/cByJ f 24.9 8.24   8 2.91 0.331 13.4, 41.9 -0.12
BALB/cByJ m 29.5 11.1   7 4.21 0.378 15.7, 50.1 0.05
BTBR T+ Itpr3tf/J f 26.0 7.85   8 2.78 0.302 17.1, 41.5 -0.02
BTBR T+ Itpr3tf/J m 31.9 13.9   6 5.69 0.437 21.4, 58.8 0.24
BUB/BnJ f 15.2 6.42   5 2.87 0.421 9.5, 25.9 -1.06
BUB/BnJ m 12.2 2.09   6 0.853 0.171 8.7, 14.6 -1.32
C3H/HeJ f 42.5 9.22   7 3.48 0.217 28.0, 54.6 1.57
C3H/HeJ m 41.3 4.74   8 1.68 0.115 32.6, 46.9 0.98
C57BL/10J f 14.3 6.94   7 2.62 0.484 7.1, 28.4 -1.14
C57BL/10J m 13.2 6.45   13 1.79 0.489 6.9, 27.7 -1.24
C57BL/6J f 11.7 3.35   7 1.26 0.286 8.1, 16.9 -1.39
C57BL/6J m 10.3 2.22   7 0.838 0.216 7.0, 13.3 -1.47
C57BLKS/J m 14.1 5.28   16 1.32 0.375 9.2, 31.7 -1.17
C57BR/cdJ f 20.8 9.25   8 3.27 0.444 11.1, 42.1 -0.52
C57BR/cdJ m 10.7 2.93   8 1.04 0.273 8.2, 17.4 -1.44
C57L/J f 30.2 12.8   7 4.82 0.423 20.8, 57.2 0.39
C57L/J m 22.7 19.5   7 7.37 0.859 9.5, 65.7 -0.49
CAST/EiJ f 13.6 3.72   8 1.32 0.273 8.6, 18.6 -1.21
CBA/J f 21.5 7.07   2   5.0 0.329 16.5, 26.5 -0.45
CBA/J m 43.2 15.3   5 6.85 0.354 29.4, 61.7 1.13
DBA/2J f 25.3 5.67   6 2.31 0.224 17.7, 35.0 -0.08
DBA/2J m 34.8 14.9   6 6.07 0.427 21.6, 63.1 0.47
FVB/NJ f 23.1 9.4   7 3.55 0.407 15.3, 38.1 -0.3
FVB/NJ m 44.7 22.1   12 6.37 0.494 25.6, 88.1 1.25
KK/HlJ f 49.3 9.16   6 3.74 0.186 35.9, 61.2 2.22
KK/HlJ m 40.0 9.43   7 3.56 0.236 28.1, 56.9 0.88
LP/J m 22.2 4.66   8 1.65 0.21 13.3, 28.2 -0.53
MRL/MpJ f 53.1 14.2   7 5.37 0.267 32.9, 75.9 2.59
MRL/MpJ m 43.5 8.21   8 2.9 0.189 32.1, 57.6 1.15
NOD.B10Sn-H2b/J f 26.4 10.7   7 4.05 0.406 16.9, 49.0 0.02
NOD.B10Sn-H2b/J m 35.0 12.9   7 4.89 0.37 7.8, 48.0 0.48
NON/ShiLtJ f 38.8 8.05   5 3.6 0.208 30.6, 49.6 1.21
NON/ShiLtJ m 49.0 15.2   7 5.75 0.31 31.1, 72.1 1.59
NZO/HlLtJ f 21.6 8.17   10 2.58 0.378 8.9, 33.7 -0.44
NZO/HlLtJ m 20.1 4.81   2   3.4 0.239 16.7, 23.5 -0.7
NZW/LacJ f 9.33 5.83   7 2.2 0.625 1.5, 19.4 -1.62
NZW/LacJ m 19.1 4.01   6 1.64 0.21 14.7, 26.0 -0.77
P/J f 23.3 8.02   7 3.03 0.344 15.1, 39.0 -0.28
P/J m 28.4 14.1   5 6.31 0.497 12.4, 47.4 -0.04
PL/J f 37.1 4.13   8 1.46 0.111 31.4, 44.3 1.05
PL/J m 45.6 17.6   8 6.23 0.386 33.9, 87.2 1.32
PWD/PhJ f 22.4 2.97   6 1.21 0.132 18.9, 26.3 -0.36
PWD/PhJ m 21.7 5.06   7 1.91 0.233 15.2, 27.7 -0.57
RIIIS/J f 23.5 10.1   8 3.56 0.428 10.7, 43.7 -0.26
RIIIS/J m 17.1 2.56   8 0.905 0.15 14.1, 20.5 -0.93
SJL/J f 31.5 13.5   7 5.09 0.428 14.5, 51.3 0.51
SJL/J m 30.8 6.61   4 3.3 0.214 22.1, 37.2 0.15
SM/J f 23.7 4.58   6 1.87 0.193 16.6, 29.4 -0.24
SM/J m 19.3 3.53   9 1.18 0.183 14.1, 24.1 -0.76
SWR/J f 27.9 17.4   7 6.56 0.621 13.4, 52.9 0.17
SWR/J m 13.7 3.04   8 1.07 0.221 10.3, 18.2 -1.2
WSB/EiJ f 22.0 5.18   8 1.83 0.236 16.1, 30.5 -0.4
WSB/EiJ m 37.5 15.1   9 5.02 0.402 23.9, 67.7 0.68


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 24.1 3.7741 31.5241 16.6759
129S1/SvImJ m 50.1 4.0347 58.0367 42.1633
A/J f 29.6857 4.0347 37.6224 21.749
A/J m 36.1867 2.7562 41.6084 30.7649
BALB/cByJ f 24.8875 3.7741 32.3116 17.4634
BALB/cByJ m 29.4857 4.0347 37.4224 21.549
BTBR T+ Itpr3tf/J f 25.9875 3.7741 33.4116 18.5634
BTBR T+ Itpr3tf/J m 31.9 4.358 40.4726 23.3274
BUB/BnJ f 15.24 4.7739 24.6308 5.8492
BUB/BnJ m 12.2 4.358 20.7726 3.6274
C3H/HeJ f 42.5 4.0347 50.4367 34.5633
C3H/HeJ m 41.325 3.7741 48.7491 33.9009
C57BL/10J f 14.3286 4.0347 22.2652 6.3919
C57BL/10J m 13.1846 2.9607 19.0085 7.3607
C57BL/6J f 11.7143 4.0347 19.651 3.7776
C57BL/6J m 10.2714 4.0347 18.2081 2.3348
C57BR/cdJ f 20.8125 3.7741 28.2366 13.3884
C57BR/cdJ m 10.7375 3.7741 18.1616 3.3134
C57L/J f 30.1571 4.0347 38.0938 22.2205
C57L/J m 22.6857 4.0347 30.6224 14.749
CBA/J f 21.5 7.5483 36.3481 6.6519
CBA/J m 43.24 4.7739 52.6308 33.8492
DBA/2J f 25.3 4.358 33.8726 16.7274
DBA/2J m 34.8 4.358 43.3726 26.2274
FVB/NJ f 23.1143 4.0347 31.051 15.1776
FVB/NJ m 44.6833 3.0816 50.7451 38.6216
KK/HlJ f 49.3333 4.358 57.9059 40.7608
KK/HlJ m 40.0 4.0347 47.9367 32.0633
MRL/MpJ f 53.0857 4.0347 61.0224 45.149
MRL/MpJ m 43.5 3.7741 50.9241 36.0759
NOD.B10Sn-H2b/J f 26.4 4.0347 34.3367 18.4633
NOD.B10Sn-H2b/J m 34.9714 4.0347 42.9081 27.0348
NON/ShiLtJ f 38.76 4.7739 48.1508 29.3692
NON/ShiLtJ m 49.0429 4.0347 56.9795 41.1062
NZO/HlLtJ f 21.62 3.3757 28.2603 14.9797
NZO/HlLtJ m 20.1 7.5483 34.9481 5.2519
NZW/LacJ f 9.3286 4.0347 17.2652 1.3919
NZW/LacJ m 19.0833 4.358 27.6559 10.5108
P/J f 23.2857 4.0347 31.2224 15.349
P/J m 28.38 4.7739 37.7708 18.9892
PL/J f 37.0875 3.7741 44.5116 29.6634
PL/J m 45.6125 3.7741 53.0366 38.1884
PWD/PhJ f 22.45 4.358 31.0226 13.8774
PWD/PhJ m 21.7 4.0347 29.6367 13.7633
RIIIS/J f 23.5 3.7741 30.9241 16.0759
RIIIS/J m 17.075 3.7741 24.4991 9.6509
SJL/J f 31.4857 4.0347 39.4224 23.549
SJL/J m 30.825 5.3374 41.3242 20.3258
SM/J f 23.7 4.358 32.2726 15.1274
SM/J m 19.2889 3.5583 26.2884 12.2894
SWR/J f 27.9286 4.0347 35.8652 19.9919
SWR/J m 13.7125 3.7741 21.1366 6.2884
WSB/EiJ f 21.9875 3.7741 29.4116 14.5634
WSB/EiJ m 37.5111 3.5583 44.5106 30.5116


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 37.1 2.7624 42.5339 31.6661
A/J both 32.9362 2.4431 37.7421 28.1303
BALB/cByJ both 27.1866 2.7624 32.6205 21.7527
BTBR T+ Itpr3tf/J both 28.9438 2.8825 34.614 23.2735
BUB/BnJ both 13.72 3.232 20.0776 7.3624
C3H/HeJ both 41.9125 2.7624 47.3464 36.4786
C57BL/10J both 13.7566 2.5022 18.6787 8.8345
C57BL/6J both 10.9929 2.853 16.6049 5.3808
C57BR/cdJ both 15.775 2.6687 21.0246 10.5254
C57L/J both 26.4214 2.853 32.0335 20.8094
CBA/J both 32.37 4.4656 41.1543 23.5857
DBA/2J both 30.05 3.0816 36.1117 23.9883
FVB/NJ both 33.8988 2.5385 38.8922 28.9054
KK/HlJ both 44.6667 2.9695 50.5079 38.8254
MRL/MpJ both 48.2929 2.7624 53.7267 42.859
NOD.B10Sn-H2b/J both 30.6857 2.853 36.2978 25.0736
NON/ShiLtJ both 43.9014 3.1253 50.0491 37.7537
NZO/HlLtJ both 20.86 4.1344 28.9927 12.7273
NZW/LacJ both 14.206 2.9695 20.0472 8.3647
P/J both 25.8329 3.1253 31.9806 19.6851
PL/J both 41.35 2.6687 46.5996 36.1004
PWD/PhJ both 22.075 2.9695 27.9162 16.2338
RIIIS/J both 20.2875 2.6687 25.5371 15.0379
SJL/J both 31.1554 3.3454 37.7361 24.5746
SM/J both 21.4944 2.8131 27.028 15.9609
SWR/J both 20.8205 2.7624 26.2544 15.3867
WSB/EiJ both 29.7493 2.5935 34.851 24.6476




  GWAS USING LINEAR MIXED MODELS