Project measure / variable:   Jaxpheno4   HCT16

ID, description, units MPD:22969   HCT16   hematocrit (HCT)   [%]  at age age 16wks  
Data set, strains Jaxpheno4   inbred   9 strains     sex: both     age: 16wks
Procedure complete blood count
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  STRAIN COMPARISON PLOT
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Jaxpheno4 - hematocrit (HCT) at age age 16wks



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means47.6   % 49.1   %
Median of the strain means47.2   % 48.5   %
SD of the strain means± 2.28 ± 2.84
Coefficient of variation (CV)0.0480 0.0578
Min–max range of strain means43.7   –   51.2   % 45.8   –   54.1   %
Mean sample size per strain15.7   mice 15.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 116.3028 116.3028 20.4347 < 0.0001
strain 8 1502.631 187.8289 33.002 < 0.0001
sex:strain 8 113.414 14.1767 2.4909 0.0126
Residuals 286 1627.7499 5.6914


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
B6D2F1/J f 49.4 3.22   16 0.804 0.0651 45.9, 54.0 0.8
B6D2F1/J m 54.1 2.44   10 0.771 0.0451 48.2, 56.5 1.75
BALB/cByJ f 46.8 1.49   21 0.326 0.0319 43.8, 49.3 -0.34
BALB/cByJ m 48.0 1.13   22 0.24 0.0235 46.1, 50.6 -0.4
C3H/HeJ f 43.7 0.909   10 0.288 0.0208 42.3, 44.9 -1.69
C3H/HeJ m 45.9 1.47   11 0.443 0.032 43.9, 48.3 -1.14
C57BL/6J f 51.2 2.0   35 0.337 0.039 47.6, 54.7 1.59
C57BL/6J m 51.8 3.18   30 0.581 0.0614 40.9, 55.8 0.94
CBA/J f 47.2 1.81   22 0.386 0.0384 43.0, 50.9 -0.16
CBA/J m 48.8 2.13   23 0.445 0.0437 45.1, 52.6 -0.11
DBA/2J f 47.5 1.02   11 0.306 0.0214 46.3, 49.2 -0.03
DBA/2J m 48.5 1.92   11 0.579 0.0397 45.8, 52.7 -0.22
FVB/NJ f 45.8 2.56   10 0.81 0.056 39.0, 47.8 -0.77
FVB/NJ m 47.5 1.89   11 0.571 0.0399 43.7, 51.3 -0.57
NOD.CB17-Prkdcscid/J f 46.6 1.2   10 0.38 0.0258 45.2, 49.3 -0.42
NOD.CB17-Prkdcscid/J m 45.8 2.36   10 0.748 0.0517 40.9, 48.1 -1.17
NOD/ShiLtJ f 49.9 4.61   20 1.03 0.0925 36.9, 60.2 1.02
NOD/ShiLtJ m 51.7 2.36   21 0.515 0.0456 48.0, 57.0 0.91


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6D2F1/J f 49.3562 0.5964 50.5302 48.1823
B6D2F1/J m 54.12 0.7544 55.6049 52.6351
BALB/cByJ f 46.7857 0.5206 47.8104 45.761
BALB/cByJ m 48.0227 0.5086 49.0239 47.0216
C3H/HeJ f 43.74 0.7544 45.2249 42.2551
C3H/HeJ m 45.8545 0.7193 47.2704 44.4387
C57BL/6J f 51.1971 0.4033 51.9909 50.4034
C57BL/6J m 51.7633 0.4356 52.6206 50.906
CBA/J f 47.1636 0.5086 48.1648 46.1625
CBA/J m 48.8391 0.4974 49.8183 47.86
DBA/2J f 47.5364 0.7193 48.9522 46.1206
DBA/2J m 48.4636 0.7193 49.8794 47.0478
FVB/NJ f 45.75 0.7544 47.2349 44.2651
FVB/NJ m 47.4727 0.7193 48.8885 46.0569
NOD.CB17-Prkdcscid/J f 46.61 0.7544 48.0949 45.1251
NOD.CB17-Prkdcscid/J m 45.77 0.7544 47.2549 44.2851
NOD/ShiLtJ f 49.86 0.5335 50.91 48.81
NOD/ShiLtJ m 51.7238 0.5206 52.7485 50.6991


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
B6D2F1/J both 51.7381 0.4808 52.6846 50.7917
BALB/cByJ both 47.4042 0.3639 48.1205 46.6879
C3H/HeJ both 44.7973 0.5212 45.8231 43.7714
C57BL/6J both 51.4802 0.2968 52.0644 50.8961
CBA/J both 48.0014 0.3557 48.7016 47.3012
DBA/2J both 48.0 0.5086 49.0011 46.9989
FVB/NJ both 46.6114 0.5212 47.6372 45.5855
NOD.CB17-Prkdcscid/J both 46.19 0.5335 47.24 45.14
NOD/ShiLtJ both 50.7919 0.3727 51.5255 50.0583




  GWAS USING LINEAR MIXED MODELS