Project measure / variable:   Jaxpheno4   MPV16

ID, description, units MPD:22953   MPV16   mean platelet volume (MPV)   [fL]  at age age 16wks  
Data set, strains Jaxpheno4   inbred   9 strains     sex: both     age: 16wks
Procedure complete blood count
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  STRAIN COMPARISON PLOT
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Jaxpheno4 - mean platelet volume (MPV) at age age 16wks



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means5.77   fL 6.10   fL
Median of the strain means5.55   fL 5.88   fL
SD of the strain means± 0.573 ± 0.755
Coefficient of variation (CV)0.0993 0.124
Min–max range of strain means5.11   –   6.76   fL 5.16   –   7.33   fL
Mean sample size per strain15.7   mice 15.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 4.107 4.107 14.1475 0.0002
strain 8 109.1665 13.6458 47.0061 < 0.0001
sex:strain 8 13.5745 1.6968 5.845 < 0.0001
Residuals 286 83.0255 0.2903


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
B6D2F1/J f 5.91 0.408   16 0.102 0.069 5.2, 6.7 0.25
B6D2F1/J m 7.33 0.302   10 0.0955 0.0412 6.8, 7.7 1.63
BALB/cByJ f 5.11 0.376   21 0.082 0.0735 4.7, 5.9 -1.15
BALB/cByJ m 5.53 0.461   22 0.0983 0.0834 5.0, 6.4 -0.76
C3H/HeJ f 5.44 0.327   10 0.103 0.0602 5.0, 5.9 -0.57
C3H/HeJ m 5.55 0.333   11 0.1 0.06 5.1, 6.0 -0.73
C57BL/6J f 6.57 0.457   35 0.0772 0.0695 5.9, 7.6 1.4
C57BL/6J m 6.42 0.209   30 0.0381 0.0325 5.9, 6.8 0.42
CBA/J f 6.76 1.1   22 0.235 0.163 5.3, 8.6 1.73
CBA/J m 7.22 1.1   23 0.229 0.152 5.4, 8.8 1.48
DBA/2J f 5.55 0.181   11 0.0545 0.0326 5.3, 5.9 -0.38
DBA/2J m 6.09 0.318   11 0.0958 0.0522 5.8, 6.7 -0.02
FVB/NJ f 5.44 0.117   10 0.0371 0.0216 5.2, 5.6 -0.57
FVB/NJ m 5.74 0.234   11 0.0704 0.0407 5.3, 6.1 -0.48
NOD.CB17-Prkdcscid/J f 5.25 0.259   10 0.082 0.0494 4.6, 5.5 -0.9
NOD.CB17-Prkdcscid/J m 5.16 0.158   10 0.0499 0.0306 4.9, 5.4 -1.25
NOD/ShiLtJ f 5.88 0.455   20 0.102 0.0774 5.2, 6.8 0.2
NOD/ShiLtJ m 5.88 0.403   21 0.088 0.0686 5.1, 6.4 -0.29


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6D2F1/J f 5.9125 0.1347 6.1776 5.6474
B6D2F1/J m 7.33 0.1704 7.6654 6.9946
BALB/cByJ f 5.1143 0.1176 5.3457 4.8829
BALB/cByJ m 5.5318 0.1149 5.7579 5.3057
C3H/HeJ f 5.44 0.1704 5.7754 5.1046
C3H/HeJ m 5.5455 0.1625 5.8652 5.2257
C57BL/6J f 6.5714 0.0911 6.7507 6.3922
C57BL/6J m 6.4167 0.0984 6.6103 6.223
CBA/J f 6.7636 0.1149 6.9897 6.5375
CBA/J m 7.2217 0.1123 7.4429 7.0006
DBA/2J f 5.5545 0.1625 5.8743 5.2348
DBA/2J m 6.0909 0.1625 6.4107 5.7712
FVB/NJ f 5.44 0.1704 5.7754 5.1046
FVB/NJ m 5.7364 0.1625 6.0561 5.4166
NOD.CB17-Prkdcscid/J f 5.25 0.1704 5.5854 4.9146
NOD.CB17-Prkdcscid/J m 5.16 0.1704 5.4954 4.8246
NOD/ShiLtJ f 5.88 0.1205 6.1171 5.6429
NOD/ShiLtJ m 5.881 0.1176 6.1124 5.6495


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
B6D2F1/J both 6.6212 0.1086 6.835 6.4075
BALB/cByJ both 5.3231 0.0822 5.4848 5.1613
C3H/HeJ both 5.4927 0.1177 5.7244 5.261
C57BL/6J both 6.494 0.067 6.626 6.3621
CBA/J both 6.9927 0.0803 7.1508 6.8346
DBA/2J both 5.8227 0.1149 6.0488 5.5966
FVB/NJ both 5.5882 0.1177 5.8199 5.3565
NOD.CB17-Prkdcscid/J both 5.205 0.1205 5.4421 4.9679
NOD/ShiLtJ both 5.8805 0.0842 6.0461 5.7148




  GWAS USING LINEAR MIXED MODELS