Project measure / variable:   Jaxpheno4   WBC16

ID, description, units MPD:22902   WBC16   white blood cell count (WBC; per volume x 103)   [n/µL]  at age 16wks  
Data set, strains Jaxpheno4   inbred   9 strains     sex: both     age: 16wks
Procedure complete blood count
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  STRAIN COMPARISON PLOT
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Jaxpheno4 - white blood cell count (WBC; per volume x 103) at age 16wks



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means2.54   n/µL 2.45   n/µL
Median of the strain means2.50   n/µL 2.79   n/µL
SD of the strain means± 0.911 ± 0.880
Coefficient of variation (CV)0.358 0.359
Min–max range of strain means0.780   –   4.05   n/µL 0.684   –   3.58   n/µL
Mean sample size per strain15.7   mice 15.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1.4728 1.4728 1.6338 0.2022
strain 8 134.3552 16.7944 18.6301 < 0.0001
sex:strain 8 25.4575 3.1822 3.53 0.0007
Residuals 286 257.8192 0.9015


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
B6D2F1/J f 2.58 1.32   16 0.329 0.511 1.21, 6.26 0.04
B6D2F1/J m 3.58 1.2   10 0.379 0.334 2.11, 5.78 1.28
BALB/cByJ f 3.52 1.16   21 0.254 0.331 1.96, 6.69 1.08
BALB/cByJ m 2.79 0.858   22 0.183 0.307 1.45, 4.44 0.39
C3H/HeJ f 2.39 0.549   10 0.174 0.229 1.73, 3.35 -0.17
C3H/HeJ m 2.81 0.988   11 0.298 0.351 1.68, 4.72 0.41
C57BL/6J f 2.67 1.33   35 0.225 0.498 1.18, 6.42 0.14
C57BL/6J m 3.1 1.14   30 0.209 0.368 1.67, 5.83 0.74
CBA/J f 2.5 0.62   22 0.132 0.248 1.48, 4.11 -0.05
CBA/J m 2.0 0.741   23 0.155 0.371 0.9, 3.49 -0.51
DBA/2J f 4.05 0.828   11 0.25 0.204 2.93, 5.29 1.66
DBA/2J m 3.09 0.625   11 0.188 0.203 2.19, 4.13 0.73
FVB/NJ f 2.13 0.673   10 0.213 0.316 0.96, 3.08 -0.45
FVB/NJ m 2.23 0.983   11 0.296 0.442 1.33, 4.77 -0.25
NOD.CB17-Prkdcscid/J f 0.78 0.151   10 0.0478 0.194 0.6, 0.97 -1.93
NOD.CB17-Prkdcscid/J m 0.684 0.106   10 0.0334 0.154 0.55, 0.84 -2.01
NOD/ShiLtJ f 2.25 0.839   20 0.188 0.372 1.21, 4.32 -0.32
NOD/ShiLtJ m 1.76 0.616   21 0.134 0.349 1.1, 2.93 -0.78


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6D2F1/J f 2.5762 0.2374 3.0435 2.109
B6D2F1/J m 3.585 0.3002 4.176 2.994
BALB/cByJ f 3.5176 0.2072 3.9254 3.1098
BALB/cByJ m 2.795 0.2024 3.1934 2.3966
C3H/HeJ f 2.394 0.3002 2.985 1.803
C3H/HeJ m 2.8145 0.2863 3.378 2.2511
C57BL/6J f 2.6697 0.1605 2.9856 2.3538
C57BL/6J m 3.1037 0.1733 3.4449 2.7625
CBA/J f 2.4986 0.2024 2.8971 2.1002
CBA/J m 2.0 0.198 2.3897 1.6103
DBA/2J f 4.0545 0.2863 4.618 3.4911
DBA/2J m 3.0855 0.2863 3.6489 2.522
FVB/NJ f 2.127 0.3002 2.718 1.536
FVB/NJ m 2.2264 0.2863 2.7898 1.6629
NOD.CB17-Prkdcscid/J f 0.78 0.3002 1.371 0.189
NOD.CB17-Prkdcscid/J m 0.684 0.3002 1.275 0.093
NOD/ShiLtJ f 2.2545 0.2123 2.6724 1.8366
NOD/ShiLtJ m 1.7643 0.2072 2.1721 1.3565


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
B6D2F1/J both 3.0806 0.1914 3.4573 2.704
BALB/cByJ both 3.1563 0.1448 3.4414 2.8712
C3H/HeJ both 2.6043 0.2074 3.0125 2.196
C57BL/6J both 2.8867 0.1181 3.1192 2.6542
CBA/J both 2.2493 0.1416 2.528 1.9707
DBA/2J both 3.57 0.2024 3.9684 3.1716
FVB/NJ both 2.1767 0.2074 2.585 1.7684
NOD.CB17-Prkdcscid/J both 0.732 0.2123 1.1499 0.3141
NOD/ShiLtJ both 2.0094 0.1483 2.3013 1.7174




  GWAS USING LINEAR MIXED MODELS