Project measure / variable:   Jaxpheno3   T4_16

ID, description, units MPD:22821   T4_16   thyroxine (plasma T4)   [µg/dL]  at age 16wks  
Data set, strains Jaxpheno3   inbred   8 strains     sex: both     age: 16wks
Procedure metabolic panel
Ontology mappings

  STRAIN COMPARISON PLOT
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Jaxpheno3 - thyroxine (plasma T4) at age 16wks



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means6.10   µg/dL 6.31   µg/dL
Median of the strain means6.21   µg/dL 6.11   µg/dL
SD of the strain means± 1.50 ± 1.14
Coefficient of variation (CV)0.247 0.181
Min–max range of strain means3.33   –   7.90   µg/dL 4.54   –   7.79   µg/dL
Mean sample size per strain16.2   mice 15.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 13.786 13.786 12.1627 0.0006
strain 7 331.4918 47.356 41.7798 < 0.0001
sex:strain 7 130.072 18.5817 16.3937 < 0.0001
Residuals 241 273.1654 1.1335


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
B6D2F1/J f 6.79 0.605   10 0.191 0.089 5.9, 7.5 0.46
B6D2F1/J m 5.65 0.941   10 0.297 0.167 4.4, 6.9 -0.58
BALB/cByJ f 5.33 0.748   20 0.167 0.14 4.2, 7.4 -0.51
BALB/cByJ m 5.49 0.675   16 0.169 0.123 4.3, 6.4 -0.72
C3H/HeJ f 7.83 1.11   10 0.35 0.141 6.5, 10.0 1.15
C3H/HeJ m 7.63 0.935   10 0.296 0.122 6.0, 9.2 1.15
C57BL/6J f 6.07 1.06   30 0.193 0.174 4.2, 8.3 -0.02
C57BL/6J m 4.54 0.883   30 0.161 0.194 2.5, 6.4 -1.55
CBA/J f 7.9 1.84   10 0.581 0.233 5.9, 12.2 1.2
CBA/J m 7.79 0.952   20 0.213 0.122 5.0, 9.9 1.29
DBA/2J f 6.35 1.14   10 0.36 0.179 4.5, 8.4 0.17
DBA/2J m 7.19 0.877   10 0.277 0.122 5.6, 8.6 0.77
NOD.CB17-Prkdcscid/J f 5.2 0.506   10 0.16 0.0972 4.3, 5.9 -0.6
NOD.CB17-Prkdcscid/J m 6.34 0.659   10 0.208 0.104 5.6, 7.4 0.02
NOD/ShiLtJ f 3.33 1.74   30 0.317 0.522 -1.84
NOD/ShiLtJ m 5.88 0.726   21 0.159 0.124 4.3, 7.3 -0.38


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6D2F1/J f 6.79 0.3367 7.4532 6.1268
B6D2F1/J m 5.65 0.3367 6.3132 4.9868
BALB/cByJ f 5.335 0.2381 5.8039 4.8661
BALB/cByJ m 5.4875 0.2662 6.0118 4.9632
C3H/HeJ f 7.83 0.3367 8.4932 7.1668
C3H/HeJ m 7.63 0.3367 8.2932 6.9668
C57BL/6J f 6.07 0.1944 6.4529 5.6871
C57BL/6J m 4.54 0.1944 4.9229 4.1571
CBA/J f 7.9 0.3367 8.5632 7.2368
CBA/J m 7.79 0.2381 8.2589 7.3211
DBA/2J f 6.35 0.3367 7.0132 5.6868
DBA/2J m 7.19 0.3367 7.8532 6.5268
NOD.CB17-Prkdcscid/J f 5.2 0.3367 5.8632 4.5368
NOD.CB17-Prkdcscid/J m 6.34 0.3367 7.0032 5.6768
NOD/ShiLtJ f 3.33 0.1944 3.7129 2.9471
NOD/ShiLtJ m 5.881 0.2323 6.3386 5.4233


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
B6D2F1/J both 6.22 0.2381 6.6889 5.7511
BALB/cByJ both 5.4113 0.1785 5.763 5.0595
C3H/HeJ both 7.73 0.2381 8.1989 7.2611
C57BL/6J both 5.305 0.1374 5.5757 5.0343
CBA/J both 7.845 0.2062 8.2511 7.4389
DBA/2J both 6.77 0.2381 7.2389 6.3011
NOD.CB17-Prkdcscid/J both 5.77 0.2381 6.2389 5.3011
NOD/ShiLtJ both 4.6055 0.1515 4.9038 4.3071




  GWAS USING LINEAR MIXED MODELS