Project measure / variable:   Jaxpheno3   T4_8

ID, description, units MPD:22820   T4_8   thyroxine (plasma T4)   [µg/dL]  at age 8wks  
Data set, strains Jaxpheno3   inbred   11 strains     sex: both     age: 8wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Jaxpheno3 - thyroxine (plasma T4) at age 8wks



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested11 strains11 strains
Mean of the strain means5.88   µg/dL 6.25   µg/dL
Median of the strain means5.76   µg/dL 6.70   µg/dL
SD of the strain means± 1.47 ± 1.66
Coefficient of variation (CV)0.250 0.265
Min–max range of strain means3.24   –   8.11   µg/dL 3.17   –   8.95   µg/dL
Mean sample size per strain15.8   mice 17.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.2539 0.2539 0.306 0.5805
strain 10 609.8831 60.9883 73.5096 < 0.0001
sex:strain 10 101.3095 10.131 12.2109 < 0.0001
Residuals 378 313.6131 0.8297


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
B6.129P2-Apoetm1Unc/J f 5.17 0.62   10 0.196 0.12 4.6, 6.3 -0.48
B6.129P2-Apoetm1Unc/J m 4.34 0.566   10 0.179 0.13 3.3, 5.3 -1.15
B6D2F1/J f 5.94 1.17   10 0.37 0.197 4.0, 7.6 0.04
B6D2F1/J m 7.06 0.965   10 0.305 0.137 5.5, 8.8 0.49
BALB/cByJ f 5.76 1.18   20 0.263 0.204 3.2, 8.0 -0.08
BALB/cByJ m 5.96 0.792   20 0.177 0.133 4.4, 7.5 -0.18
BALB/cJ f 8.11 0.997   20 0.223 0.123 7.0, 10.8 1.52
BALB/cJ m 7.98 0.849   22 0.181 0.106 6.0, 9.4 1.04
C3H/HeJ f 7.9 0.67   10 0.212 0.0848 7.2, 9.5 1.37
C3H/HeJ m 8.95 0.889   10 0.281 0.0993 7.8, 10.3 1.63
C57BL/6J f 5.66 1.25   30 0.229 0.221 3.6, 8.2 -0.15
C57BL/6J m 4.88 0.828   54 0.113 0.17 3.3, 6.9 -0.83
CBA/J f 7.32 1.34   21 0.293 0.183 5.0, 9.7 0.98
CBA/J m 6.7 0.6   30 0.11 0.0896 5.4, 7.9 0.27
DBA/2J f 5.0 1.1   21 0.239 0.219 2.7, 7.1 -0.6
DBA/2J m 6.78 0.724   20 0.162 0.107 5.7, 7.8 0.32
FVB/NJ f 3.24 0.536   10 0.169 0.165 2.4, 4.2 -1.8
FVB/NJ m 3.17 0.657   12 0.19 0.207 2.0, 3.9 -1.86
NOD.CB17-Prkdcscid/J f 4.44 0.369   10 0.117 0.0831 3.7, 5.0 -0.98
NOD.CB17-Prkdcscid/J m 7.15 0.948   10 0.3 0.133 5.5, 8.7 0.54
NOD/ShiLtJ f 6.16 0.881   20 0.197 0.143 4.7, 7.8 0.19
NOD/ShiLtJ m 5.79 0.7   20 0.156 0.121 3.9, 7.0 -0.28


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6.129P2-Apoetm1Unc/J f 5.17 0.288 5.7364 4.6036
B6.129P2-Apoetm1Unc/J m 4.34 0.288 4.9064 3.7736
B6D2F1/J f 5.94 0.288 6.5064 5.3736
B6D2F1/J m 7.06 0.288 7.6264 6.4936
BALB/cByJ f 5.76 0.2037 6.1605 5.3595
BALB/cByJ m 5.96 0.2037 6.3605 5.5595
BALB/cJ f 8.105 0.2037 8.5055 7.7045
BALB/cJ m 7.9818 0.1942 8.3637 7.6
C3H/HeJ f 7.9 0.288 8.4664 7.3336
C3H/HeJ m 8.95 0.288 9.5164 8.3836
C57BL/6J f 5.66 0.1663 5.987 5.333
C57BL/6J m 4.8796 0.124 5.1234 4.6359
CBA/J f 7.3238 0.1988 7.7146 6.933
CBA/J m 6.7 0.1663 7.027 6.373
DBA/2J f 5.0 0.1988 5.3908 4.6092
DBA/2J m 6.78 0.2037 7.1805 6.3795
FVB/NJ f 3.24 0.288 3.8064 2.6736
FVB/NJ m 3.1667 0.2629 3.6837 2.6497
NOD.CB17-Prkdcscid/J f 4.44 0.288 5.0064 3.8736
NOD.CB17-Prkdcscid/J m 7.15 0.288 7.7164 6.5836
NOD/ShiLtJ f 6.155 0.2037 6.5555 5.7545
NOD/ShiLtJ m 5.79 0.2037 6.1905 5.3895


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
B6.129P2-Apoetm1Unc/J both 4.755 0.2037 5.1555 4.3545
B6D2F1/J both 6.5 0.2037 6.9005 6.0995
BALB/cByJ both 5.86 0.144 6.1432 5.5768
BALB/cJ both 8.0434 0.1407 8.3201 7.7667
C3H/HeJ both 8.425 0.2037 8.8255 8.0245
C57BL/6J both 5.2698 0.1037 5.4737 5.0659
CBA/J both 7.0119 0.1296 7.2667 6.7571
DBA/2J both 5.89 0.1423 6.1698 5.6102
FVB/NJ both 3.2033 0.195 3.5868 2.8199
NOD.CB17-Prkdcscid/J both 5.795 0.2037 6.1955 5.3945
NOD/ShiLtJ both 5.9725 0.144 6.2557 5.6893




  GWAS USING LINEAR MIXED MODELS