Project measure / variable:   Brown2   fall_ave_d7

ID, description, units MPD:22567   fall_ave_d7   latency to fall from accelerating rotarod (8 rpm/min)   [s]  day7  
Data set, strains Brown2   inbred   12 strains     sex: both     age: 10-18wks
Procedure rotarod
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  STRAIN COMPARISON PLOT
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Brown2 - latency to fall from accelerating rotarod (8 rpm/min) day7



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested12 strains12 strains
Mean of the strain means172   s 149   s
Median of the strain means158   s 132   s
SD of the strain means± 62.6 ± 53.7
Coefficient of variation (CV)0.364 0.361
Min–max range of strain means101   –   304   s 82.2   –   254   s
Mean sample size per strain12.0   mice 11.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 32183.6775 32183.6775 14.8372 0.0001
strain 11 861146.8966 78286.0815 36.0911 < 0.0001
sex:strain 11 72038.4804 6548.9528 3.0192 0.0008
Residuals 271 587831.9348 2169.1215


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 185.0 48.1   12 13.9 0.26 108.0, 237.0 0.21
129S1/SvImJ m 151.0 45.6   12 13.2 0.301 63.0, 211.0 0.04
A/J f 101.0 33.1   12 9.55 0.329 65.5, 182.0 -1.13
A/J m 97.1 43.9   18 10.3 0.452 49.1, 190.0 -0.96
AKR/J f 222.0 33.3   12 9.61 0.15 178.0, 275.0 0.8
AKR/J m 254.0 50.1   12 14.5 0.197 159.0, 309.0 1.96
BALB/cByJ f 112.0 28.9   21 6.31 0.259 68.6, 183.0 -0.95
BALB/cByJ m 118.0 27.3   12 7.89 0.232 75.4, 168.0 -0.57
BALB/cJ f 101.0 24.8   14 6.63 0.245 54.7, 156.0 -1.13
BALB/cJ m 82.2 43.4   10 13.7 0.528 41.9, 193.0 -1.24
C3H/HeJ f 143.0 36.7   10 11.6 0.256 91.8, 202.0 -0.46
C3H/HeJ m 154.0 58.3   9 19.4 0.378 75.6, 239.0 0.1
C57BL/6J f 235.0 56.5   12 16.3 0.241 148.0, 351.0 1.01
C57BL/6J m 205.0 47.0   12 13.6 0.23 123.0, 283.0 1.05
DBA/2J f 136.0 29.0   12 8.38 0.213 101.0, 209.0 -0.57
DBA/2J m 117.0 44.5   12 12.8 0.381 43.3, 178.0 -0.59
FVB/NJ f 134.0 55.8   12 16.1 0.415 40.5, 216.0 -0.6
FVB/NJ m 111.0 36.9   12 10.6 0.333 69.4, 186.0 -0.7
MOLF/EiJ f 304.0 70.3   12 20.3 0.232 163.0, 360.0 2.11
MOLF/EiJ m 229.0 76.3   11 23.0 0.334 115.0, 336.0 1.5
SJL/J f 214.0 42.8   12 12.4 0.2 163.0, 291.0 0.68
SJL/J m 133.0 27.5   12 7.94 0.207 89.1, 186.0 -0.29
SM/J f 174.0 75.0   10 23.7 0.432 79.1, 316.0 0.04
SM/J m 132.0 55.9   12 16.1 0.424 45.7, 223.0 -0.31


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 185.25 13.4447 211.7194 158.7806
129S1/SvImJ m 151.2917 13.4447 177.761 124.8223
A/J f 100.525 13.4447 126.9944 74.0556
A/J m 97.0944 10.9776 118.7066 75.4823
AKR/J f 221.5 13.4447 247.9694 195.0306
AKR/J m 253.9167 13.4447 280.386 227.4473
BALB/cByJ f 111.6571 10.1632 131.6661 91.6482
BALB/cByJ m 117.975 13.4447 144.4444 91.5056
BALB/cJ f 101.3714 12.4474 125.8773 76.8656
BALB/cJ m 82.23 14.7279 111.2257 53.2343
C3H/HeJ f 143.18 14.7279 172.1757 114.1843
C3H/HeJ m 154.1778 15.5246 184.742 123.6136
C57BL/6J f 234.8333 13.4447 261.3027 208.364
C57BL/6J m 204.5833 13.4447 231.0527 178.114
DBA/2J f 136.1667 13.4447 162.636 109.6973
DBA/2J m 116.65 13.4447 143.1194 90.1806
FVB/NJ f 134.225 13.4447 160.6944 107.7556
FVB/NJ m 110.6417 13.4447 137.111 84.1723
MOLF/EiJ f 303.5 13.4447 329.9694 277.0306
MOLF/EiJ m 228.6364 14.0425 256.2827 200.99
SJL/J f 214.4167 13.4447 240.886 187.9473
SJL/J m 133.2583 13.4447 159.7277 106.789
SM/J f 173.61 14.7279 202.6057 144.6143
SM/J m 131.9 13.4447 158.3694 105.4306


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 168.2708 9.5068 186.9875 149.5542
A/J both 98.8097 8.6785 115.8956 81.7238
AKR/J both 237.7083 9.5068 256.425 218.9917
BALB/cByJ both 114.8161 8.4269 131.4066 98.2255
BALB/cJ both 91.8007 9.6417 110.7829 72.8186
C3H/HeJ both 148.6789 10.6996 169.7438 127.614
C57BL/6J both 219.7083 9.5068 238.425 200.9917
DBA/2J both 126.4083 9.5068 145.125 107.6917
FVB/NJ both 122.4333 9.5068 141.15 103.7167
MOLF/EiJ both 266.0682 9.7205 285.2055 246.9309
SJL/J both 173.8375 9.5068 192.5542 155.1208
SM/J both 152.755 9.9709 172.3852 133.1248




  GWAS USING LINEAR MIXED MODELS