Project measure / variable:   Brown2   fall_ave_d2

ID, description, units MPD:22562   fall_ave_d2   latency to fall from accelerating rotarod (8 rpm/min)   [s]  day2  
Data set, strains Brown2   inbred   12 strains     sex: both     age: 10-18wks
Procedure rotarod
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  STRAIN COMPARISON PLOT
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Brown2 - latency to fall from accelerating rotarod (8 rpm/min) day2



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested12 strains12 strains
Mean of the strain means134   s 107   s
Median of the strain means124   s 95.7   s
SD of the strain means± 63.9 ± 44.5
Coefficient of variation (CV)0.476 0.418
Min–max range of strain means57.6   –   259   s 53.1   –   168   s
Mean sample size per strain12.1   mice 11.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 46531.2106 46531.2106 25.8887 < 0.0001
strain 11 761939.5167 69267.2288 38.5385 < 0.0001
sex:strain 11 70489.6452 6408.1496 3.5653 0.0001
Residuals 272 488880.0247 1797.353


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 178.0 44.5   12 12.8 0.249 68.0, 228.0 0.68
129S1/SvImJ m 118.0 25.8   12 7.44 0.218 82.7, 176.0 0.26
A/J f 58.3 19.4   12 5.61 0.333 35.6, 90.1 -1.19
A/J m 60.1 32.0   18 7.55 0.533 18.7, 122.0 -1.04
AKR/J f 165.0 37.7   12 10.9 0.229 97.9, 226.0 0.48
AKR/J m 165.0 48.5   12 14.0 0.294 50.1, 215.0 1.31
BALB/cByJ f 82.3 29.7   21 6.49 0.361 44.6, 157.0 -0.81
BALB/cByJ m 74.6 30.9   12 8.92 0.414 37.8, 135.0 -0.72
BALB/cJ f 57.6 13.2   14 3.53 0.229 32.9, 84.4 -1.2
BALB/cJ m 53.1 18.2   10 5.75 0.342 34.7, 95.8 -1.2
C3H/HeJ f 85.1 23.3   11 7.01 0.273 53.3, 126.0 -0.77
C3H/HeJ m 108.0 62.7   9 20.9 0.582 43.5, 235.0 0.03
C57BL/6J f 212.0 46.5   12 13.4 0.219 132.0, 278.0 1.22
C57BL/6J m 168.0 35.2   12 10.2 0.21 113.0, 226.0 1.38
DBA/2J f 95.9 31.4   12 9.05 0.327 49.8, 148.0 -0.6
DBA/2J m 77.4 15.9   12 4.58 0.205 56.7, 103.0 -0.66
FVB/NJ f 105.0 48.7   12 14.1 0.465 22.2, 188.0 -0.46
FVB/NJ m 60.9 18.6   12 5.36 0.305 24.3, 90.1 -1.03
MOLF/EiJ f 259.0 82.8   12 23.9 0.32 104.0, 360.0 1.95
MOLF/EiJ m 165.0 68.3   11 20.6 0.413 67.9, 288.0 1.31
SJL/J f 142.0 28.1   12 8.1 0.197 94.2, 194.0 0.12
SJL/J m 83.3 25.3   12 7.3 0.304 49.6, 123.0 -0.52
SM/J f 171.0 70.3   10 22.2 0.411 85.1, 332.0 0.57
SM/J m 146.0 76.0   12 21.9 0.52 35.2, 273.0 0.88


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 178.5 12.2384 202.5941 154.4059
129S1/SvImJ m 118.3667 12.2384 142.4608 94.2726
A/J f 58.3333 12.2384 82.4274 34.2392
A/J m 60.1222 9.9926 79.795 40.4495
AKR/J f 164.825 12.2384 188.9191 140.7309
AKR/J m 164.925 12.2384 189.0191 140.8309
BALB/cByJ f 82.3381 9.2514 100.5515 64.1247
BALB/cByJ m 74.5583 12.2384 98.6524 50.4642
BALB/cJ f 57.6357 11.3306 79.9425 35.3289
BALB/cJ m 53.11 13.4065 79.5038 26.7162
C3H/HeJ f 85.0727 12.7826 110.2382 59.9073
C3H/HeJ m 107.7333 14.1317 135.5548 79.9119
C57BL/6J f 211.9167 12.2384 236.0108 187.8226
C57BL/6J m 167.5 12.2384 191.5941 143.4059
DBA/2J f 95.925 12.2384 120.0191 71.8309
DBA/2J m 77.4417 12.2384 101.5358 53.3476
FVB/NJ f 104.7917 12.2384 128.8858 80.6976
FVB/NJ m 60.85 12.2384 84.9441 36.7559
MOLF/EiJ f 258.8333 12.2384 282.9274 234.7392
MOLF/EiJ m 165.2636 12.7826 190.4291 140.0982
SJL/J f 142.2667 12.2384 166.3608 118.1726
SJL/J m 83.2917 12.2384 107.3858 59.1976
SM/J f 171.21 13.4065 197.6038 144.8162
SM/J m 145.9917 12.2384 170.0858 121.8976


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 148.4333 8.6539 165.4704 131.3962
A/J both 59.2278 7.8999 74.7805 43.6751
AKR/J both 164.875 8.6539 181.9121 147.8379
BALB/cByJ both 78.4482 7.6708 93.55 63.3464
BALB/cJ both 55.3729 8.7766 72.6516 38.0941
C3H/HeJ both 96.403 9.5276 115.1603 77.6458
C57BL/6J both 189.7083 8.6539 206.7454 172.6712
DBA/2J both 86.6833 8.6539 103.7204 69.6462
FVB/NJ both 82.8208 8.6539 99.8579 65.7837
MOLF/EiJ both 212.0485 8.8484 229.4685 194.6285
SJL/J both 112.7792 8.6539 129.8163 95.7421
SM/J both 158.6008 9.0763 176.4695 140.7322




  GWAS USING LINEAR MIXED MODELS