Project measure / variable:   Wiltshire1   act_EPM

ID, description, units MPD:21404   act_EPM   total locomotor activity, 5 min   [cm]  
Data set, strains Wiltshire1   inbred   25 strains     sex: both     age: 12-14wks
Procedure elevated plus maze
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  STRAIN COMPARISON PLOT
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Wiltshire1 - total locomotor activity, 5 min



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested25 strains25 strains
Mean of the strain means1575   cm 1529   cm
Median of the strain means1708   cm 1568   cm
SD of the strain means± 609 ± 531
Coefficient of variation (CV)0.387 0.347
Min–max range of strain means469   –   2581   cm 648   –   2276   cm
Mean sample size per strain4.7   mice 4.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 198.8012 198.8012 0.0016 0.968
strain 24 66606087.2819 2775253.6367 22.5922 < 0.0001
sex:strain 24 5420699.8181 225862.4924 1.8387 0.0136
Residuals 180 22111374.3988 122840.9689


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 1068.0 464.0   8 164.0 0.434 258.0, 1644.0 -0.83
129S1/SvImJ m 975.0 589.0   7 223.0 0.605 120.0, 1554.0 -1.04
A/J f 998.0 301.0   6 123.0 0.301 475.0, 1287.0 -0.95
A/J m 1452.0 164.0   6 66.9 0.113 1233.0, 1714.0 -0.15
AKR/J f 1867.0 258.0   8 91.1 0.138 1545.0, 2334.0 0.48
AKR/J m 2092.0 401.0   6 164.0 0.192 1435.0, 2656.0 1.06
BALB/cByJ f 2082.0 516.0   8 182.0 0.248 1383.0, 3023.0 0.83
BALB/cByJ m 1617.0 447.0   8 158.0 0.276 944.0, 2218.0 0.17
BUB/BnJ f 2122.0 203.0   4 101.0 0.0956 1897.0, 2385.0 0.9
BUB/BnJ m 2225.0 382.0   4 191.0 0.172 1738.0, 2545.0 1.31
C3H/HeJ f 928.0 143.0   3 82.6 0.154 763.0, 1016.0 -1.06
C3H/HeJ m 777.0 249.0   4 125.0 0.321 425.0, 1012.0 -1.42
C57BL/6J f 937.0 316.0   4 158.0 0.337 491.0, 1231.0 -1.05
C57BL/6J m 1568.0 176.0   4 87.8 0.112 1328.0, 1727.0 0.07
C57BR/cdJ f 1630.0 103.0   4 51.3 0.0629 1483.0, 1721.0 0.09
C57BR/cdJ m 1506.0 98.3   4 49.1 0.0653 1421.0, 1629.0 -0.04
C58/J f 990.0 339.0   4 170.0 0.343 698.0, 1454.0 -0.96
C58/J m 1395.0 278.0   4 139.0 0.199 1190.0, 1793.0 -0.25
CBA/J f 717.0 242.0   4 121.0 0.338 444.0, 951.0 -1.41
CBA/J m 800.0 102.0   4 50.8 0.127 650.0, 873.0 -1.37
CE/J f 1676.0 62.2   2   44.0 0.0371 1632.0, 1720.0 0.17
CE/J m 1090.0 190.0   4 94.8 0.174 847.0, 1306.0 -0.83
DBA/2J f 848.0 140.0   4 70.0 0.165 668.0, 1009.0 -1.19
DBA/2J m 903.0 188.0   3 109.0 0.208 697.0, 1066.0 -1.18
FVB/NJ f 2581.0 336.0   6 137.0 0.13 2077.0, 3069.0 1.65
FVB/NJ m 2276.0 383.0   8 135.0 0.168 1745.0, 3002.0 1.41
LG/J f 1985.0 374.0   4 187.0 0.189 1629.0, 2378.0 0.67
LG/J m 1958.0 171.0   4 85.6 0.0875 1781.0, 2138.0 0.81
MA/MyJ f 1708.0 131.0   4 65.6 0.0768 1559.0, 1878.0 0.22
MA/MyJ m 1380.0 669.0   3 386.0 0.485 670.0, 1998.0 -0.28
MRL/MpJ f 1825.0 370.0   8 131.0 0.203 1319.0, 2338.0 0.41
MRL/MpJ m 2046.0 394.0   6 161.0 0.193 1710.0, 2723.0 0.97
NOD/ShiLtJ f 2368.0 409.0   8 145.0 0.173 1851.0, 3156.0 1.3
NOD/ShiLtJ m 2276.0 340.0   8 120.0 0.15 1786.0, 2787.0 1.41
NON/ShiLtJ f 1718.0 332.0   2   235.0 0.193 1483.0, 1953.0 0.23
NON/ShiLtJ m 1994.0 584.0   4 292.0 0.293 1287.0, 2716.0 0.88
NZO/HlLtJ f 469.0 99.4   4 49.7 0.212 349.0, 557.0 -1.81
NZO/HlLtJ m 661.0 364.0   4 182.0 0.551 251.0, 1060.0 -1.63
NZW/LacJ f 2014.0 115.0   4 57.3 0.0569 1881.0, 2142.0 0.72
NZW/LacJ m 1826.0 101.0   4 50.6 0.0555 1681.0, 1917.0 0.56
P/J f 962.0 205.0   4 102.0 0.213 684.0, 1146.0 -1.01
P/J m 1148.0 362.0   2   256.0 0.315 892.0, 1404.0 -0.72
PL/J f 2351.0 255.0   4 128.0 0.109 2068.0, 2668.0 1.27
PL/J m 1988.0 296.0   4 148.0 0.149 1741.0, 2379.0 0.86
SJL/J f 1933.0 368.0   4 184.0 0.19 1622.0, 2456.0 0.59
SJL/J m 1874.0 479.0   4 239.0 0.256 1532.0, 2564.0 0.65
SM/J f 1202.0 496.0   4 248.0 0.413 637.0, 1734.0 -0.61
SM/J m 648.0 196.0   2   138.0 0.302 510.0, 787.0 -1.66
SWR/J f 2392.0 371.0   2   262.0 0.155 2129.0, 2654.0 1.34
SWR/J m 1752.0 151.0   2   106.0 0.0859 1646.0, 1859.0 0.42


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 1068.125 123.9158 1312.6394 823.6106
129S1/SvImJ m 974.8571 132.4715 1236.2541 713.4602
A/J f 997.6667 143.0856 1280.0076 715.3257
A/J m 1452.3333 143.0856 1734.6743 1169.9924
AKR/J f 1866.75 123.9158 2111.2644 1622.2356
AKR/J m 2091.6667 143.0856 2374.0076 1809.3257
BALB/cByJ f 2082.0 123.9158 2326.5144 1837.4856
BALB/cByJ m 1616.75 123.9158 1861.2644 1372.2356
BUB/BnJ f 2121.5 175.2434 2467.2956 1775.7044
BUB/BnJ m 2225.0 175.2434 2570.7956 1879.2044
C3H/HeJ f 928.0 202.3536 1327.2904 528.7096
C3H/HeJ m 777.25 175.2434 1123.0456 431.4544
C57BL/6J f 937.25 175.2434 1283.0456 591.4544
C57BL/6J m 1568.25 175.2434 1914.0456 1222.4544
C57BR/cdJ f 1630.5 175.2434 1976.2956 1284.7044
C57BR/cdJ m 1505.5 175.2434 1851.2956 1159.7044
C58/J f 989.75 175.2434 1335.5456 643.9544
C58/J m 1395.0 175.2434 1740.7956 1049.2044
CBA/J f 717.0 175.2434 1062.7956 371.2044
CBA/J m 800.5 175.2434 1146.2956 454.7044
CE/J f 1676.0 247.8316 2165.0289 1186.9711
CE/J m 1089.5 175.2434 1435.2956 743.7044
DBA/2J f 848.25 175.2434 1194.0456 502.4544
DBA/2J m 902.6667 202.3536 1301.9571 503.3763
FVB/NJ f 2580.8333 143.0856 2863.1743 2298.4924
FVB/NJ m 2276.375 123.9158 2520.8894 2031.8606
LG/J f 1984.75 175.2434 2330.5456 1638.9544
LG/J m 1957.75 175.2434 2303.5456 1611.9544
MA/MyJ f 1708.5 175.2434 2054.2956 1362.7044
MA/MyJ m 1379.6667 202.3536 1778.9571 980.3763
MRL/MpJ f 1825.375 123.9158 2069.8894 1580.8606
MRL/MpJ m 2046.5 143.0856 2328.841 1764.159
NOD/ShiLtJ f 2367.625 123.9158 2612.1394 2123.1106
NOD/ShiLtJ m 2275.875 123.9158 2520.3894 2031.3606
NON/ShiLtJ f 1718.0 247.8316 2207.0289 1228.9711
NON/ShiLtJ m 1994.25 175.2434 2340.0456 1648.4544
NZO/HlLtJ f 469.0 175.2434 814.7956 123.2044
NZO/HlLtJ m 660.75 175.2434 1006.5456 314.9544
NZW/LacJ f 2014.0 175.2434 2359.7956 1668.2044
NZW/LacJ m 1825.5 175.2434 2171.2956 1479.7044
P/J f 962.0 175.2434 1307.7956 616.2044
P/J m 1148.0 247.8316 1637.0289 658.9711
PL/J f 2351.0 175.2434 2696.7956 2005.2044
PL/J m 1988.25 175.2434 2334.0456 1642.4544
SJL/J f 1933.25 175.2434 2279.0456 1587.4544
SJL/J m 1873.75 175.2434 2219.5456 1527.9544
SM/J f 1202.0 175.2434 1547.7956 856.2044
SM/J m 648.5 247.8316 1137.5289 159.4711
SWR/J f 2391.5 247.8316 2880.5289 1902.4711
SWR/J m 1752.5 247.8316 2241.5289 1263.4711


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 1021.4911 90.6971 1200.4573 842.5248
A/J both 1225.0 101.1768 1424.6452 1025.3548
AKR/J both 1979.2083 94.6422 2165.9593 1792.4573
BALB/cByJ both 1849.375 87.6217 2022.2728 1676.4772
BUB/BnJ both 2173.25 123.9158 2417.7644 1928.7356
C3H/HeJ both 852.625 133.8443 1116.7308 588.5192
C57BL/6J both 1252.75 123.9158 1497.2644 1008.2356
C57BR/cdJ both 1568.0 123.9158 1812.5144 1323.4856
C58/J both 1192.375 123.9158 1436.8894 947.8606
CBA/J both 758.75 123.9158 1003.2644 514.2356
CE/J both 1382.75 151.7652 1682.2178 1083.2822
DBA/2J both 875.4583 133.8443 1139.5641 611.3526
FVB/NJ both 2428.6042 94.6422 2615.3552 2241.8532
LG/J both 1971.25 123.9158 2215.7644 1726.7356
MA/MyJ both 1544.0833 133.8443 1808.1891 1279.9776
MRL/MpJ both 1935.9375 94.6422 2122.6885 1749.1865
NOD/ShiLtJ both 2321.75 87.6217 2494.6478 2148.8522
NON/ShiLtJ both 1856.125 151.7652 2155.5928 1556.6572
NZO/HlLtJ both 564.875 123.9158 809.3894 320.3606
NZW/LacJ both 1919.75 123.9158 2164.2644 1675.2356
P/J both 1055.0 151.7652 1354.4678 755.5322
PL/J both 2169.625 123.9158 2414.1394 1925.1106
SJL/J both 1903.5 123.9158 2148.0144 1658.9856
SM/J both 925.25 151.7652 1224.7178 625.7822
SWR/J both 2072.0 175.2434 2417.7956 1726.2044




  GWAS USING LINEAR MIXED MODELS