Project measure / variable:   Paigen4   CHOL

ID, description, units MPD:19702   CHOL   total cholesterol (plasma)   [mg/dL]  
Data set, strains Paigen4   inbred w/CC7   43 strains     sex: both     age: 10wks
Procedure lipid profile
Ontology mappings

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  STRAIN COMPARISON PLOT
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Paigen4 - total cholesterol (plasma)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested42 strains43 strains
Mean of the strain means84.2   mg/dL 106   mg/dL
Median of the strain means78.2   mg/dL 97.4   mg/dL
SD of the strain means± 25.2 ± 30.8
Coefficient of variation (CV)0.299 0.291
Min–max range of strain means48.5   –   162   mg/dL 54.7   –   192   mg/dL
Mean sample size per strain11.8   mice 11.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 124607.2043 124607.2043 393.2692 < 0.0001
strain 41 664968.1777 16218.736 51.1875 < 0.0001
sex:strain 41 80006.3274 1951.3738 6.1587 < 0.0001
Residuals 923 292452.1953 316.8496


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 114.0 16.7   22 3.55 0.146 89.0, 143.0 1.18
129S1/SvImJ m 123.0 34.8   17 8.43 0.282 82.0, 182.0 0.56
A/J f 77.2 12.0   10 3.81 0.156 57.0, 100.0 -0.28
A/J m 89.3 15.2   12 4.38 0.17 68.0, 118.0 -0.54
AKR/J f 55.7 17.3   18 4.07 0.31 26.0, 77.0 -1.13
AKR/J m 89.3 13.4   14 3.57 0.15 74.0, 109.0 -0.54
BALB/cByJ f 75.5 7.75   17 1.88 0.103 62.0, 89.0 -0.35
BALB/cByJ m 110.0 9.63   15 2.49 0.0879 91.0, 124.0 0.13
BALB/cJ m 106.0 11.0   5 4.93 0.104 90.0, 120.0 0.0
BTBR T+ Itpr3tf/J f 97.2 10.8   11 3.27 0.111 82.0, 114.0 0.52
BTBR T+ Itpr3tf/J m 125.0 37.2   10 11.8 0.297 76.0, 182.0 0.62
BUB/BnJ f 68.6 13.3   10 4.21 0.194 49.0, 90.0 -0.62
BUB/BnJ m 99.9 14.7   10 4.64 0.147 75.0, 118.0 -0.19
C3H/HeJ f 98.2 16.7   11 5.04 0.17 74.0, 127.0 0.56
C3H/HeJ m 118.0 27.7   14 7.41 0.234 71.0, 161.0 0.39
C57BL/10J f 63.6 15.8   23 3.3 0.249 32.0, 89.0 -0.82
C57BL/10J m 66.1 4.94   8 1.75 0.0747 59.0, 72.0 -1.29
C57BL/6J f 74.0 13.7   14 3.67 0.186 56.0, 98.0 -0.41
C57BL/6J m 85.7 7.82   10 2.47 0.0912 75.0, 100.0 -0.66
C57BLKS/J f 67.8 9.38   10 2.97 0.138 54.0, 83.0 -0.65
C57BLKS/J m 89.7 12.9   12 3.74 0.144 66.0, 111.0 -0.53
C57BR/cdJ f 89.3 10.5   10 3.32 0.117 68.0, 103.0 0.2
C57BR/cdJ m 92.2 15.1   13 4.2 0.164 66.0, 114.0 -0.44
C57L/J f 81.6 15.2   15 3.93 0.187 53.0, 106.0 -0.1
C57L/J m 68.4 20.5   16 5.12 0.299 33.0, 102.0 -1.22
C58/J f 86.3 5.33   10 1.69 0.0618 76.0, 93.0 0.08
C58/J m 95.3 15.4   16 3.85 0.162 75.0, 126.0 -0.34
CAST/EiJ f 57.1 3.83   11 1.16 0.0671 52.0, 63.0 -1.08
CAST/EiJ m 85.4 20.1   13 5.57 0.235 60.0, 134.0 -0.67
CBA/J f 84.4 13.4   10 4.24 0.159 64.0, 109.0 0.01
CBA/J m 97.4 6.65   8 2.35 0.0683 88.0, 106.0 -0.28
CE/J f 77.4 11.9   9 3.98 0.154 66.0, 101.0 -0.27
CE/J m 111.0 14.2   9 4.74 0.128 92.0, 131.0 0.17
CZECHII/EiJ f 79.0 20.9   11 6.3 0.264 54.0, 113.0 -0.21
CZECHII/EiJ m 77.2 10.4   12 2.99 0.134 61.0, 98.0 -0.93
DBA/1J f 48.5 6.5   10 2.06 0.134 41.0, 63.0 -1.42
DBA/1J m 92.8 10.4   15 2.69 0.112 80.0, 113.0 -0.42
DBA/2J f 63.6 7.25   9 2.42 0.114 52.0, 75.0 -0.82
DBA/2J m 118.0 10.7   12 3.08 0.0903 106.0, 140.0 0.39
FVB/NJ f 130.0 21.6   10 6.82 0.166 102.0, 166.0 1.82
FVB/NJ m 166.0 22.3   14 5.95 0.134 139.0, 205.0 1.95
I/LnJ f 55.9 10.1   11 3.04 0.18 43.0, 73.0 -1.12
I/LnJ m 80.8 14.9   13 4.14 0.185 53.0, 109.0 -0.82
JF1/MsJ f 59.5 11.9   8 4.22 0.201 44.0, 79.0 -0.98
JF1/MsJ m 93.4 6.98   10 2.21 0.0747 83.0, 102.0 -0.41
KK/HlJ f 162.0 21.7   9 7.25 0.134 137.0, 202.0 3.09
KK/HlJ m 186.0 56.0   11 16.9 0.302 84.0, 267.0 2.61
LP/J f 97.6 21.1   16 5.27 0.216 64.0, 130.0 0.53
LP/J m 89.2 30.0   8 10.6 0.337 33.0, 127.0 -0.54
MA/MyJ f 112.0 20.3   10 6.42 0.181 94.0, 164.0 1.11
MA/MyJ m 156.0 16.4   9 5.47 0.105 132.0, 176.0 1.63
MOLF/EiJ f 88.5 13.6   14 3.63 0.154 62.0, 113.0 0.17
MOLF/EiJ m 80.1 16.8   14 4.49 0.21 53.0, 108.0 -0.84
MSM/MsJ f 87.5 8.42   11 2.54 0.0962 76.0, 101.0 0.13
MSM/MsJ m 77.5 15.2   11 4.6 0.197 60.0, 103.0 -0.92
NOD/ShiLtJ f 85.3 12.0   9 4.0 0.141 65.0, 102.0 0.04
NOD/ShiLtJ m 110.0 16.0   20 3.58 0.145 79.0, 137.0 0.13
NON/ShiLtJ f 106.0 9.09   10 2.88 0.0855 89.0, 116.0 0.87
NON/ShiLtJ m 154.0 15.2   14 4.06 0.0984 121.0, 182.0 1.56
NZB/BlNJ f 158.0 23.4   11 7.04 0.148 122.0, 193.0 2.93
NZB/BlNJ m 192.0 37.0   10 11.7 0.193 141.0, 262.0 2.8
NZW/LacJ f 110.0 25.9   12 7.47 0.235 85.0, 152.0 1.03
NZW/LacJ m 139.0 11.5   10 3.65 0.0832 122.0, 155.0 1.08
PERA/EiJ f 68.2 15.1   8 5.33 0.221 52.0, 96.0 -0.64
PERA/EiJ m 66.8 6.98   8 2.47 0.105 58.0, 75.0 -1.27
PL/J f 76.4 26.7   25 5.35 0.35 18.0, 124.0 -0.31
PL/J m 100.0 20.4   12 5.89 0.204 62.0, 129.0 -0.19
PWK/PhJ f 79.2 6.91   10 2.18 0.0872 66.0, 88.0 -0.2
PWK/PhJ m 79.0 9.18   12 2.65 0.116 65.0, 102.0 -0.87
RF/J f 71.5 20.8   18 4.9 0.291 36.0, 98.0 -0.5
RF/J m 128.0 20.3   16 5.07 0.158 99.0, 173.0 0.72
RIIIS/J f 53.6 6.68   12 1.93 0.125 41.0, 64.0 -1.22
RIIIS/J m 54.7 7.23   13 2.0 0.132 43.0, 67.0 -1.66
SEA/GnJ f 76.3 6.78   7 2.56 0.0888 67.0, 84.0 -0.31
SEA/GnJ m 107.0 24.6   10 7.79 0.23 81.0, 149.0 0.04
SJL/J f 61.9 5.93   9 1.98 0.0957 51.0, 71.0 -0.89
SJL/J m 91.7 6.36   9 2.12 0.0694 78.0, 100.0 -0.46
SM/J f 65.7 10.0   13 2.78 0.153 44.0, 82.0 -0.74
SM/J m 93.5 13.2   11 3.98 0.141 72.0, 117.0 -0.4
SPRET/EiJ f 108.0 15.5   11 4.68 0.144 79.0, 135.0 0.95
SPRET/EiJ m 134.0 11.8   10 3.74 0.0884 116.0, 150.0 0.91
SWR/J f 89.8 25.3   10 8.01 0.282 46.0, 134.0 0.22
SWR/J m 117.0 13.1   14 3.5 0.112 94.0, 141.0 0.36
WSB/EiJ f 74.2 7.73   9 2.58 0.104 67.0, 89.0 -0.4
WSB/EiJ m 117.0 8.73   8 3.09 0.0748 104.0, 132.0 0.36


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 113.9091 3.795 121.357 106.4612
129S1/SvImJ m 123.2353 4.3172 131.708 114.7626
A/J f 77.2 5.6289 88.247 66.153
A/J m 89.3333 5.1385 99.4178 79.2488
AKR/J f 55.7222 4.1956 63.9562 47.4883
AKR/J m 89.2857 4.7573 98.6221 79.9493
BALB/cByJ f 75.5294 4.3172 84.0021 67.0567
BALB/cByJ m 109.5333 4.596 118.5532 100.5135
BTBR T+ Itpr3tf/J f 97.1818 5.367 107.7147 86.6489
BTBR T+ Itpr3tf/J m 125.3 5.6289 136.347 114.253
BUB/BnJ f 68.6 5.6289 79.647 57.553
BUB/BnJ m 99.9 5.6289 110.947 88.853
C3H/HeJ f 98.1818 5.367 108.7147 87.6489
C3H/HeJ m 118.2857 4.7573 127.6221 108.9493
C57BL/10J f 63.6087 3.7116 70.8929 56.3245
C57BL/10J m 66.125 6.2933 78.4759 53.7741
C57BL/6J f 74.0 4.7573 83.3364 64.6636
C57BL/6J m 85.7 5.6289 96.747 74.653
C57BLKS/J f 67.8 5.6289 78.847 56.753
C57BLKS/J m 89.6667 5.1385 99.7512 79.5822
C57BR/cdJ f 89.3 5.6289 100.347 78.253
C57BR/cdJ m 92.2308 4.9369 101.9196 82.5419
C57L/J f 81.6 4.596 90.6198 72.5802
C57L/J m 68.375 4.4501 77.1084 59.6416
C58/J f 86.3 5.6289 97.347 75.253
C58/J m 95.3125 4.4501 104.0459 86.5791
CAST/EiJ f 57.0909 5.367 67.6238 46.558
CAST/EiJ m 85.3846 4.9369 95.0735 75.6958
CBA/J f 84.4 5.6289 95.447 73.353
CBA/J m 97.375 6.2933 109.7259 85.0241
CE/J f 77.4444 5.9334 89.089 65.7999
CE/J m 110.7778 5.9334 122.4223 99.1332
CZECHII/EiJ f 79.0 5.367 89.5329 68.4671
CZECHII/EiJ m 77.1667 5.1385 87.2512 67.0822
DBA/1J f 48.5 5.6289 59.547 37.453
DBA/1J m 92.8 4.596 101.8198 83.7802
DBA/2J f 63.5556 5.9334 75.2001 51.911
DBA/2J m 118.0 5.1385 128.0845 107.9155
FVB/NJ f 130.2 5.6289 141.247 119.153
FVB/NJ m 166.2857 4.7573 175.6221 156.9493
I/LnJ f 55.9091 5.367 66.442 45.3762
I/LnJ m 80.7692 4.9369 90.4581 71.0804
JF1/MsJ f 59.5 6.2933 71.8509 47.1491
JF1/MsJ m 93.4 5.6289 104.447 82.353
KK/HlJ f 161.8889 5.9334 173.5335 150.2443
KK/HlJ m 185.8182 5.367 196.3511 175.2853
LP/J f 97.625 4.4501 106.3584 88.8916
LP/J m 89.25 6.2933 101.6009 76.8991
MA/MyJ f 112.2 5.6289 123.247 101.153
MA/MyJ m 156.3333 5.9334 167.9779 144.6888
MOLF/EiJ f 88.5 4.7573 97.8364 79.1636
MOLF/EiJ m 80.0714 4.7573 89.4079 70.735
MSM/MsJ f 87.5455 5.367 98.0784 77.0125
MSM/MsJ m 77.4545 5.367 87.9875 66.9216
NOD/ShiLtJ f 85.3333 5.9334 96.9779 73.6888
NOD/ShiLtJ m 110.3 3.9803 118.1114 102.4886
NON/ShiLtJ f 106.3 5.6289 117.347 95.253
NON/ShiLtJ m 154.3571 4.7573 163.6936 145.0207
NZB/BlNJ f 158.0909 5.367 168.6238 147.558
NZB/BlNJ m 191.7 5.6289 202.747 180.653
NZW/LacJ f 110.0833 5.1385 120.1678 99.9988
NZW/LacJ m 138.8 5.6289 149.847 127.753
PERA/EiJ f 68.25 6.2933 80.6009 55.8991
PERA/EiJ m 66.75 6.2933 79.1009 54.3991
PL/J f 76.36 3.5601 83.3467 69.3733
PL/J m 100.3333 5.1385 110.4178 90.2488
PWK/PhJ f 79.2 5.6289 90.247 68.153
PWK/PhJ m 79.0 5.1385 89.0845 68.9155
RF/J f 71.5 4.1956 79.734 63.266
RF/J m 128.125 4.4501 136.8584 119.3916
RIIIS/J f 53.5833 5.1385 63.6678 43.4988
RIIIS/J m 54.6923 4.9369 64.3812 45.0034
SEA/GnJ f 76.2857 6.7279 89.4894 63.082
SEA/GnJ m 107.0 5.6289 118.047 95.953
SJL/J f 61.8889 5.9334 73.5335 50.2443
SJL/J m 91.6667 5.9334 103.3112 80.0221
SM/J f 65.6923 4.9369 75.3812 56.0034
SM/J m 93.4545 5.367 103.9875 82.9216
SPRET/EiJ f 108.0909 5.367 118.6238 97.558
SPRET/EiJ m 133.7 5.6289 144.747 122.653
SWR/J f 89.8 5.6289 100.847 78.753
SWR/J m 116.5714 4.7573 125.9079 107.235
WSB/EiJ f 74.2222 5.9334 85.8668 62.5777
WSB/EiJ m 116.75 6.2933 129.1009 104.3991


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 118.5722 2.874 124.2126 112.9318
A/J both 83.2667 3.8108 90.7455 75.7878
AKR/J both 72.504 3.1715 78.7283 66.2797
BALB/cByJ both 92.5314 3.1528 98.7189 86.3438
BTBR T+ Itpr3tf/J both 111.2409 3.8887 118.8727 103.6091
BUB/BnJ both 84.25 3.9803 92.0614 76.4386
C3H/HeJ both 108.2338 3.586 115.2714 101.1962
C57BL/10J both 64.8668 3.6532 72.0363 57.6974
C57BL/6J both 79.85 3.685 87.082 72.618
C57BLKS/J both 78.7333 3.8108 86.2122 71.2545
C57BR/cdJ both 90.7654 3.7436 98.1123 83.4184
C57L/J both 74.9875 3.1987 81.265 68.71
C58/J both 90.8063 3.5878 97.8474 83.7651
CAST/EiJ both 71.2378 3.6461 78.3935 64.0821
CBA/J both 90.8875 4.2217 99.1728 82.6022
CE/J both 94.1111 4.1956 102.3451 85.8772
CZECHII/EiJ both 78.0833 3.7151 85.3744 70.7923
DBA/1J both 70.65 3.6335 77.7808 63.5192
DBA/2J both 90.7778 3.9246 98.4799 83.0756
FVB/NJ both 148.2429 3.685 155.4748 141.0109
I/LnJ both 68.3392 3.6461 75.4949 61.1835
JF1/MsJ both 76.45 4.2217 84.7353 68.1647
KK/HlJ both 173.8535 4.0003 181.7043 166.0028
LP/J both 93.4375 3.8539 101.0009 85.8741
MA/MyJ both 134.2667 4.0893 142.2921 126.2412
MOLF/EiJ both 84.2857 3.3639 90.8876 77.6839
MSM/MsJ both 82.5 3.795 89.9479 75.0521
NOD/ShiLtJ both 97.8167 3.5724 104.8276 90.8057
NON/ShiLtJ both 130.3286 3.685 137.5605 123.0966
NZB/BlNJ both 174.8955 3.8887 182.5273 167.2636
NZW/LacJ both 124.4417 3.8108 131.9205 116.9628
PERA/EiJ both 67.5 4.4501 76.2334 58.7666
PL/J both 88.3467 3.1256 94.4808 82.2125
PWK/PhJ both 79.1 3.8108 86.5789 71.6211
RF/J both 99.8125 3.058 105.814 93.811
RIIIS/J both 54.1378 3.5629 61.1302 47.1455
SEA/GnJ both 91.6429 4.386 100.2506 83.0351
SJL/J both 76.7778 4.1956 85.0117 68.5438
SM/J both 79.5734 3.6461 86.7291 72.4177
SPRET/EiJ both 120.8955 3.8887 128.5273 113.2636
SWR/J both 103.1857 3.685 110.4177 95.9538
WSB/EiJ both 95.4861 4.3247 103.9735 86.9987




  GWAS USING LINEAR MIXED MODELS