Phenotype measure:   Chang1   rod_Awave

ID, description, units MPD:15701   rod_Awave   a-wave amplitude of rod photoreceptors (ERG)   [µV]
Data set, strains Chang1   inbred   15 strains     sex: both     age: >7wks
Procedure electroretinography
Ontology mappings

  STRAIN COMPARISON PLOT
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Chang1 - a-wave amplitude of rod photoreceptors (ERG)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested15 strains8 strains
Mean of the strain means91.4   µV 99.4   µV
Median of the strain means84.0   µV 88.5   µV
SD of the strain means± 43.5 ± 43.8
Coefficient of variation (CV)0.476 0.441
Min–max range of strain means25.4   –   179   µV 50.5   –   185   µV
Mean sample size per strain10.4   mice 16.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 60009.6154 60009.6154 15.1765 0.0001
strain 6 768223.3343 128037.2224 32.3808 < 0.0001
sex:strain 6 3045.3564 507.5594 0.1284 0.9927
Residuals 246 972709.4478 3954.1034


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 59.9 60.2   17 14.6 1.01 -0.72
BALB/cByJ f 88.2 61.0   10 19.3 0.691 3.0, 180.0 -0.07
BALB/cByJ m 91.6 58.8   5 26.3 0.642 40.0, 185.0 -0.18
BALB/cJ f 128.0 76.8   9 25.6 0.601 40.0, 270.0 0.84
C57BL/10J f 165.0 60.6   14 16.2 0.366 66.0, 244.0 1.69
C57BL/6J f 179.0 67.9   63 8.55 0.379 15.0, 330.0 2.01
C57BL/6J m 185.0 74.2   90 7.82 0.4 15.0, 500.0 1.95
C57BR/cdJ f 108.0 82.7   5 37.0 0.763 40.0, 235.0 0.38
CAST/EiJ f 66.2 28.0   4 14.0 0.422 30.0, 97.0 -0.58
CE/J f 71.5 36.5   10 11.5 0.51 30.0, 130.0 -0.46
CE/J m 85.4 48.1   5 21.5 0.563 35.0, 150.0 -0.32
CZECHII/EiJ f 66.0 32.5   4 16.2 0.492 28.0, 95.0 -0.58
CZECHII/EiJ m 61.0 8.08   4 4.04 0.133 50.0, 68.0 -0.88
DBA/2J f 122.0 24.3   7 9.2 0.2 90.0, 160.0 0.7
LP/J f 42.0 37.7   11 11.4 0.897 5.0, 107.0 -1.14
NZW/LacJ f 107.0 52.8   9 17.6 0.495 40.0, 185.0 0.36
NZW/LacJ m 106.0 28.0   4 14.0 0.265 70.0, 135.0 0.15
PERA/EiJ f 58.5 53.2   26 10.4 0.909 -0.76
PERA/EiJ m 77.6 36.2   16 9.05 0.467 10.0, 148.0 -0.5
PWK/PhJ m 138.0 14.3   4 7.17 0.104 120.0, 155.0 0.88
SPRET/EiJ f 84.0 31.7   5 14.2 0.378 46.0, 120.0 -0.17
WSB/EiJ f 25.4 23.7   8 8.36 0.932 -1.52
WSB/EiJ m 50.5 34.8   6 14.2 0.689 18.0, 100.0 -1.11


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BALB/cByJ f 88.2 19.8849 127.3664 49.0336
BALB/cByJ m 91.6 28.1215 146.9897 36.2103
C57BL/6J f 179.2698 7.9223 194.8741 163.6656
C57BL/6J m 185.4778 6.6283 198.5333 172.4223
CE/J f 71.5 19.8849 110.6664 32.3336
CE/J m 85.4 28.1215 140.7897 30.0103
CZECHII/EiJ f 66.0 31.4408 127.9276 4.0724
CZECHII/EiJ m 61.0 31.4408 122.9276 0.0
NZW/LacJ f 106.7778 20.9606 148.0628 65.4927
NZW/LacJ m 105.75 31.4408 167.6776 43.8224
PERA/EiJ f 58.4615 12.3321 82.7515 34.1715
PERA/EiJ m 77.5625 15.7204 108.5263 46.5987
WSB/EiJ f 25.375 22.232 69.1644 0.0
WSB/EiJ m 50.5 25.6713 101.0636 0.0


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
BALB/cByJ both 89.9 17.2209 123.8191 55.9809
C57BL/6J both 182.3738 5.1647 192.5466 172.2011
CE/J both 78.45 17.2209 112.3691 44.5309
CZECHII/EiJ both 63.5 22.232 107.2894 19.7106
NZW/LacJ both 106.2639 18.8936 143.4777 69.0501
PERA/EiJ both 68.012 9.9901 87.6892 48.3349
WSB/EiJ both 37.9375 16.98 71.3822 4.4928




  GWAS USING LINEAR MIXED MODELS