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Project measure / variable:   Justice2   PLT

ID, description, units MPD:13211   PLT   platelet count (PLT; units per volume x 103)   [n/µL]  
Data set, strains Justice2   inbred   16 strains     sex: both     age: 12-16wks
Procedure complete blood count
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  STRAIN COMPARISON PLOT
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Justice2 - platelet count (PLT; units per volume x 103)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested16 strains16 strains
Mean of the strain means1020   n/µL 1100   n/µL
Median of the strain means1049   n/µL 1112   n/µL
SD of the strain means± 153 ± 185
Coefficient of variation (CV)0.150 0.168
Min–max range of strain means745   –   1275   n/µL 733   –   1453   n/µL
Mean sample size per strain12.5   mice 12.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 632481.4496 632481.4496 44.5344 < 0.0001
strain 15 9855477.9834 657031.8656 46.263 < 0.0001
sex:strain 15 1477293.5126 98486.2342 6.9346 < 0.0001
Residuals 359 5098550.7884 14202.0913


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 745.0 64.3   15 16.6 0.0862 628.0, 908.0 -1.8
129S1/SvImJ m 733.0 46.9   15 12.1 0.064 643.0, 830.0 -1.99
129S6/SvEvTac f 784.0 86.4   10 27.3 0.11 548.0, 846.0 -1.54
129S6/SvEvTac m 762.0 141.0   10 44.7 0.185 448.0, 922.0 -1.83
A/J f 1177.0 86.6   10 27.4 0.0735 1028.0, 1311.0 1.03
A/J m 1103.0 120.0   8 42.3 0.109 989.0, 1306.0 0.02
BALB/cByJ f 1087.0 124.0   15 32.1 0.114 931.0, 1311.0 0.44
BALB/cByJ m 1315.0 141.0   15 36.5 0.108 1092.0, 1502.0 1.17
BALB/cJ f 1181.0 67.1   10 21.2 0.0568 1042.0, 1284.0 1.05
BALB/cJ m 1132.0 147.0   9 49.1 0.13 974.0, 1372.0 0.17
BTBR T+ Itpr3tf/J f 1044.0 58.4   10 18.5 0.0559 966.0, 1130.0 0.16
BTBR T+ Itpr3tf/J m 1137.0 65.3   10 20.6 0.0574 1021.0, 1235.0 0.2
C3HeB/FeJ f 977.0 164.0   14 43.8 0.168 693.0, 1151.0 -0.28
C3HeB/FeJ m 976.0 164.0   15 42.3 0.168 588.0, 1259.0 -0.67
C3H/HeJ f 986.0 76.8   10 24.3 0.0779 889.0, 1093.0 -0.22
C3H/HeJ m 1052.0 67.9   10 21.5 0.0645 959.0, 1161.0 -0.26
C57BL/10J f 1086.0 63.4   13 17.6 0.0584 1007.0, 1188.0 0.43
C57BL/10J m 1162.0 68.0   15 17.6 0.0585 1022.0, 1271.0 0.34
C57BL/6J f 1080.0 79.2   15 20.4 0.0734 949.0, 1180.0 0.39
C57BL/6J m 1311.0 78.9   14 21.1 0.0601 1178.0, 1426.0 1.14
CAST/EiJ f 817.0 60.7   10 19.2 0.0743 747.0, 968.0 -1.33
CAST/EiJ m 1202.0 167.0   9 55.5 0.139 934.0, 1437.0 0.55
CBA/CaJ f 931.0 110.0   13 30.6 0.118 724.0, 1161.0 -0.58
CBA/CaJ m 1090.0 179.0   14 47.8 0.164 793.0, 1314.0 -0.05
CBA/J f 912.0 129.0   10 40.7 0.141 748.0, 1191.0 -0.71
CBA/J m 1036.0 54.2   7 20.5 0.0523 973.0, 1144.0 -0.35
DBA/2J f 1182.0 150.0   15 38.8 0.127 999.0, 1494.0 1.06
DBA/2J m 1121.0 109.0   12 31.3 0.0968 894.0, 1272.0 0.11
FVB/NJ f 1275.0 106.0   15 27.3 0.0828 1039.0, 1494.0 1.67
FVB/NJ m 1453.0 145.0   15 37.4 0.0996 1067.0, 1671.0 1.91
SJL/J f 1054.0 152.0   15 39.2 0.144 848.0, 1404.0 0.22
SJL/J m 1012.0 207.0   13 57.3 0.204 698.0, 1293.0 -0.48


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 745.4667 30.7702 805.9792 684.9541
129S1/SvImJ m 733.0667 30.7702 793.5792 672.5541
129S6/SvEvTac f 784.1 37.6857 858.2124 709.9876
129S6/SvEvTac m 762.2 37.6857 836.3124 688.0876
A/J f 1177.4 37.6857 1251.5124 1103.2876
A/J m 1103.375 42.1339 1186.2352 1020.5148
BALB/cByJ f 1086.9333 30.7702 1147.4459 1026.4208
BALB/cByJ m 1314.8 30.7702 1375.3125 1254.2875
BALB/cJ f 1180.7 37.6857 1254.8124 1106.5876
BALB/cJ m 1132.3333 39.7242 1210.4547 1054.212
BTBR T+ Itpr3tf/J f 1044.0 37.6857 1118.1124 969.8876
BTBR T+ Itpr3tf/J m 1137.0 37.6857 1211.1124 1062.8876
C3HeB/FeJ f 976.6429 31.8502 1039.2793 914.0065
C3HeB/FeJ m 975.6 30.7702 1036.1125 915.0875
C3H/HeJ f 985.7 37.6857 1059.8124 911.5876
C3H/HeJ m 1052.1 37.6857 1126.2124 977.9876
C57BL/10J f 1086.3846 33.0525 1151.3855 1021.3837
C57BL/10J m 1162.2 30.7702 1222.7125 1101.6875
C57BL/6J f 1079.6667 30.7702 1140.1792 1019.1541
C57BL/6J m 1311.1429 31.8502 1373.7793 1248.5065
CAST/EiJ f 817.1 37.6857 891.2124 742.9876
CAST/EiJ m 1201.5556 39.7242 1279.6769 1123.4342
CBA/CaJ f 931.0769 33.0525 996.0778 866.0761
CBA/CaJ m 1089.7143 31.8502 1152.3507 1027.0779
CBA/J f 911.7 37.6857 985.8124 837.5876
CBA/J m 1036.2857 45.043 1124.867 947.7045
DBA/2J f 1181.9333 30.7702 1242.4459 1121.4208
DBA/2J m 1120.8333 34.4021 1188.4884 1053.1783
FVB/NJ f 1275.3333 30.7702 1335.8459 1214.8208
FVB/NJ m 1453.2 30.7702 1513.7125 1392.6875
SJL/J f 1054.4667 30.7702 1114.9792 993.9541
SJL/J m 1011.6154 33.0525 1076.6163 946.6145


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 739.2667 21.7578 782.0555 696.4779
129S6/SvEvTac both 773.15 26.6478 825.5554 720.7446
A/J both 1140.3875 28.2642 1195.9718 1084.8032
BALB/cByJ both 1200.8667 21.7578 1243.6555 1158.0779
BALB/cJ both 1156.5167 27.378 1210.3581 1102.6753
BTBR T+ Itpr3tf/J both 1090.5 26.6478 1142.9054 1038.0946
C3HeB/FeJ both 976.1214 22.143 1019.6676 932.5752
C3H/HeJ both 1018.9 26.6478 1071.3054 966.4946
C57BL/10J both 1124.2923 22.5792 1168.6964 1079.8883
C57BL/6J both 1195.4048 22.143 1238.951 1151.8586
CAST/EiJ both 1009.3278 27.378 1063.1692 955.4864
CBA/CaJ both 1010.3956 22.9505 1055.5299 965.2613
CBA/J both 973.9929 29.3644 1031.7408 916.2449
DBA/2J both 1151.3833 23.0777 1196.7677 1105.9989
FVB/NJ both 1364.2667 21.7578 1407.0555 1321.4779
SJL/J both 1033.041 22.5792 1077.4451 988.637




  GWAS USING LINEAR MIXED MODELS