Project measure / variable:   Justice2   MCHC


  STRAIN COMPARISON PLOT
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Justice2 - mean RBC corpuscular hemoglobin concentration (MCHC)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested16 strains16 strains
Mean of the strain means33.9   g/dL 33.5   g/dL
Median of the strain means34.0   g/dL 33.7   g/dL
SD of the strain means± 0.667 ± 0.727
Coefficient of variation (CV)0.0197 0.0217
Min–max range of strain means32.8   –   35.1   g/dL 32.1   –   34.3   g/dL
Mean sample size per strain12.6   mice 12.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 16.5907 16.5907 92.4967 < 0.0001
strain 15 184.4967 12.2998 68.5739 < 0.0001
sex:strain 15 5.2875 0.3525 1.9653 0.0168
Residuals 366 65.6477 0.1794


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 33.3 0.353   15 0.0911 0.0106 32.3, 33.8 -0.82
129S1/SvImJ m 32.9 0.457   15 0.118 0.0139 32.2, 33.5 -0.77
129S6/SvEvTac f 33.1 0.254   10 0.0803 0.00768 32.6, 33.3 -1.12
129S6/SvEvTac m 32.7 0.275   10 0.087 0.00842 32.3, 33.1 -1.05
A/J f 34.0 0.268   10 0.0847 0.00786 33.8, 34.6 0.22
A/J m 33.7 0.266   8 0.094 0.0079 33.4, 34.1 0.33
BALB/cByJ f 34.7 0.181   15 0.0467 0.0052 34.4, 35.1 1.27
BALB/cByJ m 34.2 0.271   15 0.07 0.00793 33.6, 34.5 1.01
BALB/cJ f 35.1 0.218   10 0.069 0.00622 34.8, 35.4 1.87
BALB/cJ m 34.3 0.313   9 0.104 0.0091 33.8, 34.9 1.15
BTBR T+ Itpr3tf/J f 34.1 0.238   10 0.0752 0.00698 33.8, 34.5 0.37
BTBR T+ Itpr3tf/J m 34.0 0.334   10 0.106 0.00981 33.3, 34.4 0.74
C3HeB/FeJ f 34.3 0.393   15 0.102 0.0115 33.6, 34.9 0.67
C3HeB/FeJ m 34.2 0.436   15 0.113 0.0128 33.5, 34.9 1.01
C3H/HeJ f 34.5 0.276   10 0.0872 0.00801 34.0, 34.9 0.97
C3H/HeJ m 34.3 0.421   10 0.133 0.0123 33.6, 34.9 1.15
C57BL/10J f 32.8 0.254   13 0.0706 0.00775 32.4, 33.2 -1.57
C57BL/10J m 32.5 0.342   15 0.0883 0.0105 31.9, 33.0 -1.32
C57BL/6J f 33.5 0.35   15 0.0904 0.0105 33.0, 34.2 -0.52
C57BL/6J m 32.6 0.484   14 0.129 0.0149 32.1, 33.7 -1.19
CAST/EiJ f 33.9 0.45   10 0.142 0.0133 33.3, 34.8 0.07
CAST/EiJ m 33.9 0.269   9 0.0898 0.00795 33.3, 34.2 0.6
CBA/CaJ f 34.2 0.883   14 0.236 0.0258 33.1, 36.2 0.52
CBA/CaJ m 33.7 0.752   14 0.201 0.0223 31.7, 35.0 0.33
CBA/J f 33.9 0.493   10 0.156 0.0145 33.1, 34.6 0.07
CBA/J m 33.7 0.372   9 0.124 0.0111 33.3, 34.1 0.33
DBA/2J f 33.3 0.371   15 0.0959 0.0111 32.7, 34.0 -0.82
DBA/2J m 32.9 0.383   14 0.102 0.0117 32.1, 33.5 -0.77
FVB/NJ f 34.1 0.793   15 0.205 0.0233 33.3, 36.7 0.37
FVB/NJ m 33.7 0.168   15 0.0435 0.005 33.5, 34.1 0.33
SJL/J f 32.8 0.287   15 0.074 0.00874 32.3, 33.3 -1.57
SJL/J m 32.1 0.458   14 0.123 0.0143 31.4, 32.8 -1.87


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 33.28 0.1094 33.495 33.065
129S1/SvImJ m 32.9 0.1094 33.115 32.685
129S6/SvEvTac f 33.07 0.1339 33.3334 32.8066
129S6/SvEvTac m 32.67 0.1339 32.9334 32.4066
A/J f 34.05 0.1339 34.3134 33.7866
A/J m 33.675 0.1497 33.9694 33.3806
BALB/cByJ f 34.7467 0.1094 34.9617 34.5316
BALB/cByJ m 34.1933 0.1094 34.4084 33.9783
BALB/cJ f 35.09 0.1339 35.3534 34.8266
BALB/cJ m 34.3444 0.1412 34.6221 34.0668
BTBR T+ Itpr3tf/J f 34.09 0.1339 34.3534 33.8266
BTBR T+ Itpr3tf/J m 34.04 0.1339 34.3034 33.7766
C3HeB/FeJ f 34.32 0.1094 34.535 34.105
C3HeB/FeJ m 34.18 0.1094 34.395 33.965
C3H/HeJ f 34.45 0.1339 34.7134 34.1866
C3H/HeJ m 34.32 0.1339 34.5834 34.0566
C57BL/10J f 32.8154 0.1175 33.0464 32.5844
C57BL/10J m 32.5133 0.1094 32.7284 32.2983
C57BL/6J f 33.46 0.1094 33.675 33.245
C57BL/6J m 32.6071 0.1132 32.8297 32.3846
CAST/EiJ f 33.93 0.1339 34.1934 33.6666
CAST/EiJ m 33.8667 0.1412 34.1443 33.5891
CBA/CaJ f 34.1643 0.1132 34.3869 33.9417
CBA/CaJ m 33.7214 0.1132 33.944 33.4988
CBA/J f 33.86 0.1339 34.1234 33.5966
CBA/J m 33.6889 0.1412 33.9665 33.4113
DBA/2J f 33.3067 0.1094 33.5217 33.0916
DBA/2J m 32.8714 0.1132 33.094 32.6488
FVB/NJ f 34.06 0.1094 34.275 33.845
FVB/NJ m 33.6867 0.1094 33.9017 33.4716
SJL/J f 32.7733 0.1094 32.9884 32.5583
SJL/J m 32.0643 0.1132 32.2869 31.8417


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 33.09 0.0773 33.2421 32.9379
129S6/SvEvTac both 32.87 0.0947 33.0562 32.6838
A/J both 33.8625 0.1004 34.06 33.665
BALB/cByJ both 34.47 0.0773 34.6221 34.3179
BALB/cJ both 34.7172 0.0973 34.9086 34.5259
BTBR T+ Itpr3tf/J both 34.065 0.0947 34.2512 33.8788
C3HeB/FeJ both 34.25 0.0773 34.4021 34.0979
C3H/HeJ both 34.385 0.0947 34.5712 34.1988
C57BL/10J both 32.6644 0.0802 32.8222 32.5066
C57BL/6J both 33.0336 0.0787 33.1883 32.8788
CAST/EiJ both 33.8983 0.0973 34.0897 33.707
CBA/CaJ both 33.9429 0.08 34.1002 33.7855
CBA/J both 33.7744 0.0973 33.9658 33.5831
DBA/2J both 33.089 0.0787 33.2438 32.9343
FVB/NJ both 33.8733 0.0773 34.0254 33.7213
SJL/J both 32.4188 0.0787 32.5736 32.2641




  GWAS USING LINEAR MIXED MODELS