Project measure / variable:   Justice2   WBC

ID, description, units MPD:13204   WBC   white blood cell count (WBC; per volume x 103)   [n/µL]  
Data set, strains Justice2   inbred   16 strains     sex: both     age: 12-16wks
Procedure complete blood count
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  STRAIN COMPARISON PLOT
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Justice2 - white blood cell count (WBC; per volume x 103)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested16 strains16 strains
Mean of the strain means6.32   n/µL 6.85   n/µL
Median of the strain means5.87   n/µL 6.33   n/µL
SD of the strain means± 1.53 ± 1.75
Coefficient of variation (CV)0.243 0.256
Min–max range of strain means4.62   –   9.43   n/µL 3.56   –   10.5   n/µL
Mean sample size per strain12.6   mice 12.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 37.4301 37.4301 16.2587 0.0001
strain 15 808.2529 53.8835 23.4057 < 0.0001
sex:strain 15 105.1687 7.0112 3.0455 0.0001
Residuals 366 842.5886 2.3022


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 7.6 1.36   15 0.352 0.179 5.2, 10.2 0.84
129S1/SvImJ m 8.01 1.32   15 0.34 0.165 6.3, 10.8 0.66
129S6/SvEvTac f 9.39 2.31   10 0.729 0.246 6.4, 12.9 2.0
129S6/SvEvTac m 8.78 1.5   10 0.475 0.171 6.3, 11.0 1.1
A/J f 4.67 0.814   10 0.257 0.174 3.4, 6.0 -1.07
A/J m 6.24 1.85   8 0.654 0.297 4.3, 10.1 -0.35
BALB/cByJ f 6.27 1.21   15 0.312 0.193 4.8, 8.3 -0.03
BALB/cByJ m 5.66 1.57   15 0.406 0.278 2.2, 8.9 -0.68
BALB/cJ f 4.82 1.23   10 0.389 0.255 3.2, 6.7 -0.98
BALB/cJ m 3.56 1.66   9 0.554 0.467 1.2, 6.7 -1.88
BTBR T+ Itpr3tf/J f 9.43 1.15   10 0.365 0.122 7.9, 11.4 2.03
BTBR T+ Itpr3tf/J m 8.87 1.34   10 0.425 0.152 7.4, 11.7 1.15
C3HeB/FeJ f 5.82 1.23   15 0.318 0.211 4.02, 8.6 -0.32
C3HeB/FeJ m 6.15 1.47   15 0.38 0.239 3.5, 8.3 -0.4
C3H/HeJ f 5.23 0.855   10 0.27 0.164 3.9, 6.4 -0.71
C3H/HeJ m 6.41 1.26   10 0.398 0.197 4.3, 8.1 -0.25
C57BL/10J f 5.51 1.05   13 0.291 0.19 3.1, 6.7 -0.53
C57BL/10J m 7.46 1.22   15 0.315 0.163 5.9, 9.6 0.35
C57BL/6J f 5.92 1.07   15 0.277 0.181 4.2, 7.5 -0.26
C57BL/6J m 6.22 2.68   14 0.716 0.431 1.8, 10.2 -0.36
CAST/EiJ f 5.15 1.82   10 0.576 0.354 3.0, 8.9 -0.76
CAST/EiJ m 5.53 1.78   9 0.592 0.321 3.4, 7.9 -0.75
CBA/CaJ f 6.36 1.89   14 0.506 0.298 3.2, 8.9 0.03
CBA/CaJ m 8.06 1.56   14 0.417 0.194 6.1, 10.8 0.69
CBA/J f 4.62 1.16   10 0.368 0.252 3.3, 7.2 -1.11
CBA/J m 4.84 1.01   9 0.336 0.208 3.1, 6.5 -1.15
DBA/2J f 6.61 0.982   15 0.253 0.149 4.5, 9.0 0.19
DBA/2J m 7.68 1.33   14 0.355 0.173 6.1, 10.0 0.47
FVB/NJ f 5.73 0.79   15 0.204 0.138 4.7, 7.5 -0.38
FVB/NJ m 5.61 1.37   15 0.353 0.244 2.3, 7.9 -0.71
SJL/J f 7.94 1.72   15 0.444 0.216 5.2, 10.9 1.06
SJL/J m 10.5 2.68   14 0.715 0.254 7.1, 14.4 2.08


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 7.6 0.3918 8.3704 6.8296
129S1/SvImJ m 8.0067 0.3918 8.7771 7.2363
129S6/SvEvTac f 9.39 0.4798 10.3335 8.4465
129S6/SvEvTac m 8.78 0.4798 9.7235 7.8365
A/J f 4.67 0.4798 5.6135 3.7265
A/J m 6.2375 0.5364 7.2924 5.1826
BALB/cByJ f 6.2667 0.3918 7.0371 5.4963
BALB/cByJ m 5.66 0.3918 6.4304 4.8896
BALB/cJ f 4.82 0.4798 5.7635 3.8765
BALB/cJ m 3.5556 0.5058 4.5501 2.561
BTBR T+ Itpr3tf/J f 9.43 0.4798 10.3735 8.4865
BTBR T+ Itpr3tf/J m 8.87 0.4798 9.8135 7.9265
C3HeB/FeJ f 5.8233 0.3918 6.5937 5.0529
C3HeB/FeJ m 6.1533 0.3918 6.9237 5.3829
C3H/HeJ f 5.23 0.4798 6.1735 4.2865
C3H/HeJ m 6.41 0.4798 7.3535 5.4665
C57BL/10J f 5.5077 0.4208 6.3352 4.6802
C57BL/10J m 7.46 0.3918 8.2304 6.6896
C57BL/6J f 5.92 0.3918 6.6904 5.1496
C57BL/6J m 6.2214 0.4055 7.0189 5.424
CAST/EiJ f 5.15 0.4798 6.0935 4.2065
CAST/EiJ m 5.5333 0.5058 6.5279 4.5388
CBA/CaJ f 6.3571 0.4055 7.1546 5.5597
CBA/CaJ m 8.0571 0.4055 8.8546 7.2597
CBA/J f 4.62 0.4798 5.5635 3.6765
CBA/J m 4.8444 0.5058 5.839 3.8499
DBA/2J f 6.6067 0.3918 7.3771 5.8363
DBA/2J m 7.6786 0.4055 8.476 6.8811
FVB/NJ f 5.7267 0.3918 6.4971 4.9563
FVB/NJ m 5.6067 0.3918 6.3771 4.8363
SJL/J f 7.94 0.3918 8.7104 7.1696
SJL/J m 10.5357 0.4055 11.3331 9.7383


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 7.8033 0.277 8.3481 7.2586
129S6/SvEvTac both 9.085 0.3393 9.7522 8.4178
A/J both 5.4538 0.3599 6.1614 4.7461
BALB/cByJ both 5.9633 0.277 6.5081 5.4186
BALB/cJ both 4.1878 0.3486 4.8732 3.5023
BTBR T+ Itpr3tf/J both 9.15 0.3393 9.8172 8.4828
C3HeB/FeJ both 5.9883 0.277 6.5331 5.4436
C3H/HeJ both 5.82 0.3393 6.4872 5.1528
C57BL/10J both 6.4838 0.2875 7.0492 5.9185
C57BL/6J both 6.0707 0.2819 6.6251 5.5163
CAST/EiJ both 5.3417 0.3486 6.0271 4.6562
CBA/CaJ both 7.2071 0.2867 7.771 6.6433
CBA/J both 4.7322 0.3486 5.4177 4.0468
DBA/2J both 7.1426 0.2819 7.697 6.5882
FVB/NJ both 5.6667 0.277 6.2114 5.1219
SJL/J both 9.2379 0.2819 9.7922 8.6835




  GWAS USING LINEAR MIXED MODELS