MPD: JaxKOMP-LAP measure: all

JaxKOMP-LAP phenotype measure: all_paws2

MPD and LIMS short name	all_paws2 forehind_limb_strength_t2
Phenotype description	forelimb and hindlimb grip strength by trial, trial2 [g]
MPD and LIMS phenotype procedure	grip strength grip strength View protocol
MPD measure ID, data type	101565 numeric data
Number of genotypes	119 genotypes completed with analytics available, both sexes
Age at testing	66-72wks Late Adult Phenotyping study LAP

Ontology mappings

Data points below are the computed genotype effect size for each KOMP genotype vs. C57BL6/NJ controls.

MULTIPLE GENOTYPE PROFILE PLOT

Dimensions Width: × Height: px

Plot Options Alphabetical Order Standard Error Show Effect Sizes RankZ

Significance Threshold p-Value Threshold Adjusted Unadjusted

Download Plot

Genotype	Genotype Effect	Genotype Effect SE	Genotype Effect RankZ	Adjusted p-value	Unadjusted p-value

Abcd3^em1(IMPC)J -/-	4.1433	15.402	0.21043	0.951	0.790
Acadsb^em1(IMPC)J -/-	-6.0287	10.066	-0.47704	0.864	0.554
Acy1^em1(IMPC)J -/-	-9.7349	7.5561	-0.72791	0.569	0.209
Adad2^em1(IMPC)J -/-	-16.502	6.5032	-1.1503	0.177	0.0161
Adamtsl4^em1(IMPC)J -/-	-6.0260	10.176	-0.45376	0.864	0.559
Afmid^em1Llp -/-	-2.8381	7.8156	-0.27498	0.916	0.719
Agbl1^em1(IMPC)J/Mmjax -/-	-9.7964	10.091	-0.75542	0.667	0.341
Alg8^em1(IMPC)J/Mmjax -/+	55.377	12.625	2.3940	0.309	0.0482
Alg9^em1(IMPC)J/Mmjax -/+	-6.4152	12.672	-0.52440	0.877	0.619
Apmap^em1(IMPC)J/Mmjax -/-	-21.908	10.057	-1.4395	0.289	0.0377
Arap3^em1(IMPC)J -/-	-5.3181	11.581	-0.43073	0.910	0.650
AU040320^em1(IMPC)J -/-	4.5667	10.896	0.25335	0.915	0.679
Brip1^em1(IMPC)J/Mmjax -/-	-12.011	11.292	-0.96742	0.614	0.299
C1qc^em1(IMPC)J -/-	-0.95946	10.742	-0.14674	0.979	0.930
C7^em1(IMPC)J/Mmjax -/-	5.6700	7.1917	0.34069	0.758	0.438
Catsperz^{tm1.1(KOMP)Vlcg} -/-	-2.7055	11.669	-0.25335	0.953	0.818
Ccdc28a^{tm3b(EUCOMM)Wtsi}/2J -/-	3.3135	10.622	0.12566	0.938	0.757
Cdc42bpb^em1(IMPC)J -/+	-13.150	10.795	-1.0364	0.571	0.235
Cgref1^em1(IMPC)J/Mmjax -/-	22.253	8.3348	1.3830	0.177	0.0137
Clptm1l^em1(IMPC)J/Mmjax -/-	-9.4687	10.179	-0.67449	0.696	0.362
Cr2^em1Llp -/-	10.560	9.8971	0.67449	0.614	0.299
Diaph3^{tm1b(KOMP)Mbp}/2J -/+	6.3148	9.8508	0.36292	0.837	0.528
Dnajb2^em1(IMPC)J -/-	8.2248	10.440	0.52440	0.758	0.437
Dnase1l2^em1(IMPC)J -/-	6.7384	12.321	0.43073	0.868	0.589
Drc7^em1(IMPC)J -/-	17.348	19.362	1.0729	0.723	0.383
Dusp18^em1(IMPC)J/Mmjax -/-	0.53984	12.348	-0.083652	0.979	0.966
Eef1b2^em1(IMPC)J/Mmjax -/-	25.744	14.381	1.5011	0.390	0.0886
Egfem1^em1(IMPC)J -/-	-45.562	14.467	-2.3940	0.390	0.0878
Fkbp6^{tm1b(KOMP)Wtsi} -/-	-11.282	7.1964	-0.87177	0.459	0.127
Frmpd1^em1(IMPC)J -/-	-4.5283	28.962	-0.38532	0.963	0.890
Gm20498^em1(IMPC)J/Mmjax -/-	-11.613	6.4818	-0.90273	0.390	0.0833
Gpr15^em1(IMPC)J -/-	14.121	13.858	0.90273	0.644	0.319
Gramd3^em1(IMPC)J/Mmjax -/-	30.140	9.9843	1.9600	0.158	0.00988
Gsto1^em1(IMPC)J/Mmjax -/-	13.049	10.346	0.87177	0.569	0.220
Gtpbp10^{tm1b(KOMP)Mbp} -/-	17.015	9.0230	1.0364	0.367	0.0710
Hipk4^{tm1b(KOMP)Mbp} -/-	0.73758	7.0651	0.0	0.979	0.918
Hsbp1l1^em1(IMPC)J -/-	19.802	34.419	1.2354	0.868	0.605
Idh3b^em1(IMPC)J/Mmjax -/-	4.1380	10.666	0.18912	0.915	0.702
Igsf11^{tm1b(KOMP)Wtsi} -/-	18.130	5.5377	1.1108	0.0892	0.00300
Kcnd3^em1(IMPC)J -/-	0.48928	14.673	-0.020890	0.979	0.974
Klhl22^em1(IMPC)J/Mmjax -/-	-0.56301	11.978	-0.10463	0.979	0.963
Krt80^em1(IMPC)J -/-	-3.7211	14.467	-0.36292	0.951	0.799
Kynu^em1(IMPC)J/Mmjax -/-	11.652	15.610	0.70095	0.790	0.465
Lpgat1^em1(IMPC)J/Mmjax -/-	-8.1431	7.0830	-0.59776	0.594	0.261
Lrp1^{tm1.1(KOMP)Wtsi} -/+	6.6591	17.126	0.40792	0.915	0.703
Mapk15^{tm1b(EUCOMM)Hmgu} -/-	-24.917	12.753	-1.6449	0.341	0.0630
Mfsd4b4^em1(IMPC)J/Mmjax -/-	9.8653	7.8285	0.64849	0.569	0.218
Mlx^{tm1.1(KOMP)Vlcg} -/-	-27.360	8.0796	-1.8339	0.0857	0.00184
Mmaa^em1(IMPC)J/Mmjax -/-	-8.6042	10.765	-0.62293	0.758	0.440
Nt5dc1^em1(IMPC)J -/-	6.5616	9.9098	0.38532	0.827	0.514
Nt5dc2^em1(IMPC)J/Mmjax -/-	8.8293	7.4237	0.57297	0.574	0.246
Nup37^{tm1.1(KOMP)Vlcg}/2J -/-	-20.155	17.695	-1.2816	0.594	0.270
Otogl^em1(IMPC)J -/-	11.878	12.263	0.72791	0.667	0.342
Ovch2^{tm1b(KOMP)Mbp} -/-	8.0607	9.9082	0.50058	0.758	0.421
Patj^em1(IMPC)J -/-	2.2433	12.374	0.041789	0.963	0.858
Pcgf1^{tm1.1(KOMP)Vlcg} -/+	-3.1163	11.048	-0.29674	0.951	0.781
Phkb^em1(IMPC)J/Mmjax -/+	9.8516	9.1412	0.62293	0.614	0.293
Plod2^em1(IMPC)J/Mmjax -/+	-20.298	10.186	-1.3306	0.337	0.0594
Polr1c^em1(IMPC)J/Mmjax -/+	-17.820	12.123	-1.2354	0.541	0.157
Prss2^{tm1.1(KOMP)Vlcg} -/-	-1.4861	8.9931	-0.18912	0.963	0.871
Ptprk^em1(IMPC)J/Mmjax -/-	12.197	8.9110	0.81222	0.545	0.188
Pus1^em1(IMPC)J/Mmjax -/-	-10.446	7.6249	-0.78350	0.543	0.178
Rab34^{tm1b(EUCOMM)Hmgu} -/+	4.7787	9.1682	0.29674	0.868	0.606
Rad21l^{tm1b(KOMP)Wtsi} -/-	12.611	7.0193	0.84162	0.390	0.0806
Rbpms2^em1(IMPC)J -/-	-3.3195	9.4757	-0.31864	0.916	0.731
Rec8^{tm1b(KOMP)Wtsi}/2J -/-	-8.8972	6.5581	-0.64849	0.543	0.182
Rgs22^{tm1b(KOMP)Wtsi} -/-	-10.861	8.8328	-0.81222	0.571	0.229
Rimklb^{tm1.1(KOMP)Vlcg} -/-	3.6353	9.4518	0.14674	0.915	0.703
Rnf10^em1(IMPC)J -/-	-4.6921	8.8913	-0.40792	0.868	0.602
Rtl10^em1(IMPC)J/Mmjax -/-	18.976	8.6850	1.1503	0.289	0.0389
Rxylt1^em1(IMPC)J/Mmjax -/+	-2.2857	15.224	-0.21043	0.963	0.882
Scamp2^em1(IMPC)J -/-	2.1659	49.086	0.020890	0.979	0.972
Sebox^em1(IMPC)J -/-	-9.5946	14.040	-0.70095	0.817	0.501
Secisbp2l^em1(IMPC)J/Mmjax -/-	-26.571	8.7069	-1.7317	0.108	0.00455
Serpina1f^em1(IMPC)J -/-	29.525	10.646	1.8339	0.177	0.0108
Setd6^{tm1.1(KOMP)Mbp}/3J -/-	21.247	9.1008	1.3306	0.263	0.0283
Sh3rf3^em1(IMPC)J/Mmjax -/-	-12.414	7.6837	-1.0013	0.437	0.117
Slc41a2^em1(IMPC)J/Mmjax -/-	-21.258	10.285	-1.3830	0.309	0.0519
Snx3^{tm1.1(KOMP)Vlcg} -/+	4.5585	8.5478	0.23183	0.868	0.598
Sp5^{tm1b(KOMP)Wtsi} -/-	19.296	13.445	1.1918	0.541	0.164
Spag17^{tm1b(KOMP)Wtsi} -/-	27.754	6.1624	1.6449	0.0137	0.000116
Spink12^em1(IMPC)J -/-	7.7389	9.4457	0.47704	0.758	0.420
Sprr1a^em1(IMPC)J -/-	-22.649	15.696	-1.5011	0.541	0.164
Srbd1^em1(IMPC)J/Mmjax -/+	25.941	10.051	1.5689	0.177	0.0164
St6galnac3^em1(IMPC)J -/-	-0.35065	13.433	-0.062707	0.979	0.979
Stag3^{tm1e.1(KOMP)Wtsi}/2J -/-	0.46250	9.1325	-0.041789	0.979	0.960
Svep1^{tm1b(EUCOMM)Hmgu} -/+	-3.3999	8.2456	-0.34069	0.915	0.683
Syce1^{tm1b(KOMP)Wtsi}/2J -/-	2.8095	6.7375	0.10463	0.915	0.679
Taco1^em1(IMPC)J/Mmjax -/+	51.425	13.720	2.1280	0.0857	0.00216
Taco1^em1(IMPC)J/Mmjax -/-	7.4338	9.2498	0.45376	0.758	0.428
Tat^em1(IMPC)J/Mmjax -/-	-1.2307	9.2394	-0.16789	0.963	0.895
Tbc1d5^em1(IMPC)J -/-	-6.5226	17.099	-0.54852	0.915	0.707
Tctn3^em1(IMPC)J/Mmjax -/+	-0.91367	10.201	-0.12566	0.979	0.930
Tecpr2^em1(IMPC)J/Mmjax -/-	-14.543	11.150	-1.0729	0.569	0.207
Tex2^{tm1.1(KOMP)Vlcg}/2J -/-	-17.289	15.256	-1.1918	0.594	0.268
Thsd7a^{tm1b(KOMP)Mbp} -/-	-11.907	10.967	-0.93459	0.614	0.287
Tnnc1^em1(IMPC)J/Mmjax -/+	3.9296	7.1279	0.16789	0.868	0.586
Tpgs2^{tm1.1(KOMP)Vlcg} -/-	-21.577	8.8294	-1.1108	0.410	0.0211
Tpk1^em1(IMPC)J/Mmjax -/+	23.476	9.0247	1.4395	0.177	0.0143
Trf^em1(IMPC)J/Mmjax -/+	8.2560	6.7220	0.54852	0.571	0.231
Trip13^{tm1.1(KOMP)Vlcg} -/-	12.071	8.5428	0.75542	0.541	0.168
Tspan13^em1Llp -/-	-6.2077	8.7923	-0.50058	0.804	0.486
Ttc38^em1Llp -/-	-2.3964	10.683	-0.23183	0.953	0.825
Tuba8^em1(IMPC)J -/-	2.4961	9.5181	0.083652	0.951	0.795
Tubb2a^em1(IMPC)J -/-	14.464	11.352	0.93459	0.569	0.216
Ubap2^em1(IMPC)J/Mmjax -/-	12.176	7.1829	0.78350	0.410	0.0992
Ubiad1^em1(IMPC)J/Mmjax -/+	28.467	12.499	1.7317	0.289	0.0360
Utp4^em1(IMPC)J/Mmjax -/+	-23.687	11.468	-1.5689	0.309	0.0509
Vopp1^em1(IMPC)J -/-	4.6159	19.080	0.27498	0.953	0.811
Vwa5a^em1(IMPC)J -/-	-6.9025	33.012	-0.57297	0.963	0.854
Wdr81^em1(IMPC)J -/+	15.044	8.9094	1.0013	0.410	0.103
Yeats2^em1(IMPC)J/Mmjax -/+	2.2672	12.215	0.062707	0.963	0.854
Zc3h7a^em1(IMPC)J/Mmjax -/-	9.6825	8.0952	0.59776	0.572	0.240
Zfp174^em1(IMPC)J -/-	-11.087	15.342	-0.84162	0.798	0.476
Zfp329^em1(IMPC)J -/-	-38.189	16.458	-2.1280	0.263	0.0288
Zfp422^em1(IMPC)J -/-	20.829	9.9653	1.2816	0.309	0.0446
Zfp706^em1(IMPC)J/Mmjax -/+	14.857	8.9449	0.96742	0.416	0.108
Zfp827^em1(IMPC)J/Mmjax -/+	5.2296	14.726	0.31864	0.916	0.731
Zfp827^em1(IMPC)J/Mmjax -/-	-36.087	24.382	-1.9600	0.542	0.173

TRAIT CORRELATION PLOT

Correlate forelimb and hindlimb grip strength by trial with JaxKOMP-LAP trait: