MPD: JaxKOMP-LAP measure: QTc

JaxKOMP-LAP phenotype measure: QTc_dispersion

MPD and LIMS short name	QTc_dispersion qtc_dispersion
Phenotype description	QTc dispersion, calculated as rate-corrected QT dispersion [ms]
MPD and LIMS phenotype procedure	ECG EKG View protocol
MPD measure ID, data type	101192 numeric data
Number of genotypes	48 genotypes completed with analytics available, both sexes
Age at testing	69-75wks Late Adult Phenotyping study LAP

Ontology mappings

Data points below are the computed genotype effect size for each KOMP genotype vs. C57BL6/NJ controls.

MULTIPLE GENOTYPE PROFILE PLOT

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Plot Options Alphabetical Order Standard Error Show Effect Sizes RankZ

Significance Threshold p-Value Threshold Adjusted Unadjusted

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Genotype	Genotype Effect	Genotype Effect SE	Genotype Effect RankZ	Adjusted p-value	Unadjusted p-value

Abhd17b^em1(IMPC)J -/-	-5.4551	5.8738	-0.75712	0.684	0.363
Acadsb^em1(IMPC)J -/-	-8.2504	6.4727	-0.98113	0.684	0.216
Acy1^em1(IMPC)J -/-	-2.5125	4.4138	-0.18001	0.856	0.579
Adamtsl4^em1(IMPC)J -/-	-15.846	7.5993	-2.0454	0.392	0.0494
Alg8^em1(IMPC)J/Mmjax -/+	-2.3906	3.1660	-0.076809	0.856	0.588
Alg9^em1(IMPC)J/Mmjax -/+	8.0773	8.5244	1.0676	0.684	0.358
Anapc1^em1(IMPC)J/Mmjax -/+	-0.58125	3.7901	0.076809	0.986	0.880
Apmap^em1(IMPC)J/Mmjax -/-	-5.3274	6.1762	-0.62707	0.684	0.396
Brip1^em1(IMPC)J/Mmjax -/-	0.30139	3.0279	0.23227	0.986	0.922
C7^em1(IMPC)J/Mmjax -/-	-5.2469	3.9816	-0.56595	0.684	0.207
Cep135^em1(IMPC)J -/+	-10.877	5.4203	-1.3942	0.392	0.0572
Cgref1^em1(IMPC)J/Mmjax -/-	-3.3357	2.9380	-0.28517	0.684	0.267
Cldn13^em1(IMPC)J -/-	0.29415	7.2239	0.18001	0.986	0.970
Dnajb2^em1(IMPC)J -/-	-10.946	3.4309	-1.5446	0.177	0.00369
Dnase1l2^em1(IMPC)J -/-	0.42317	4.7938	0.28517	0.986	0.930
Drc7^em1(IMPC)J -/-	-5.3699	5.7023	-0.69063	0.684	0.416
Dusp18^em1(IMPC)J/Mmjax -/-	5.9514	4.7375	0.90145	0.684	0.336
Fbxo10^em1(IMPC)J/Mmjax -/-	-3.2643	2.5886	-0.23227	0.684	0.427
Gpr15^em1(IMPC)J -/-	1.3838	5.5031	0.56595	0.986	0.803
Gramd1c^{tm1b(KOMP)Wtsi} -/-	-7.2472	4.8214	-0.82713	0.543	0.147
Gsto1^em1(IMPC)J/Mmjax -/-	2.4941	5.3925	0.75712	0.915	0.648
Gtpbp10^{tm1b(KOMP)Mbp} -/-	-1.8633	5.8256	-0.025581	0.975	0.752
Kcnc3^em1(IMPC)J -/-	8.9170	5.1569	1.3942	0.453	0.0944
Kcnd3^em1(IMPC)J -/-	1.3143	6.7069	0.50687	0.986	0.848
Kynu^em1(IMPC)J/Mmjax -/-	1.4314	5.7419	0.62707	0.986	0.826
Mapk15^{tm1b(EUCOMM)Hmgu} -/-	7.7473	15.774	0.98113	0.968	0.709
Nt5dc1^em1(IMPC)J -/-	-4.7782	5.3764	-0.44951	0.684	0.385
Nup37^{tm1.1(KOMP)Vlcg}/2J -/-	1.0050	2.7918	0.39360	0.968	0.726
Otogl^em1(IMPC)J -/-	0.44435	6.8022	0.33889	0.986	0.949
Rbpms2^em1(IMPC)J -/-	12.077	7.6263	1.7413	0.543	0.139
Rnf10^em1(IMPC)J -/-	-10.356	4.8235	-1.2700	0.392	0.0417
Rtl10^em1(IMPC)J/Mmjax -/-	-0.10867	6.0622	0.12824	0.986	0.986
Serpina1f^em1(IMPC)J -/-	14.242	7.7419	2.0454	0.450	0.0845
Sp5^{tm1b(KOMP)Wtsi} -/-	-8.8918	4.3869	-1.0676	0.392	0.0527
Spink12^em1(IMPC)J -/-	-7.9364	4.2339	-0.90145	0.426	0.0710
Sprr1a^em1(IMPC)J -/-	-4.2491	4.9320	-0.33889	0.684	0.400
St6galnac3^em1(IMPC)J -/-	1.1137	8.4499	0.44951	0.986	0.897
Tctn3^em1(IMPC)J/Mmjax -/+	-1.7588	1.4925	0.025581	0.684	0.256
Tecpr2^em1(IMPC)J/Mmjax -/-	-9.0910	11.131	-1.1628	0.684	0.427
Tex2^{tm1.1(KOMP)Vlcg}/2J -/-	-13.779	5.6648	-1.7413	0.371	0.0232
Thsd7a^{tm1b(KOMP)Mbp} -/-	3.6725	5.0878	0.82713	0.739	0.477
Tuba8^em1(IMPC)J -/-	-5.0321	4.4865	-0.50687	0.684	0.275
Tubb2a^em1(IMPC)J -/-	8.4815	2.8945	1.1628	0.199	0.00828
Ubiad1^em1(IMPC)J/Mmjax -/+	10.14	9.1502	1.5446	0.684	0.283
Wdr81^em1(IMPC)J -/+	1.4468	5.8268	0.69063	0.986	0.806
Zfp174^em1(IMPC)J -/-	-2.5016	3.0789	-0.12824	0.684	0.428
Zfp329^em1(IMPC)J -/-	-4.6711	5.7300	-0.39360	0.684	0.424
Zfp422^em1(IMPC)J -/-	8.4824	5.1222	1.2700	0.483	0.111

TRAIT CORRELATION PLOT

Correlate QTc dispersion, calculated as rate-corrected QT dispersion with JaxKOMP-LAP trait: