MPD: JaxKOMP-LAP measure: rst

JaxKOMP-LAP phenotype measure: rst

MPD and LIMS short name	rst rst
Phenotype description	ratio of soft-tissue attenuation coefficients
MPD and LIMS phenotype procedure	DXA body composition View protocol
MPD measure ID, data type	101126 numeric data
Number of genotypes	114 genotypes completed with analytics available, both sexes
Age at testing	72-78wks Late Adult Phenotyping study LAP

Ontology mappings

Data points below are the computed genotype effect size for each KOMP genotype vs. C57BL6/NJ controls.

MULTIPLE GENOTYPE PROFILE PLOT

Genotype	Genotype Effect	Genotype Effect SE	Genotype Effect RankZ	Adjusted p-value	Unadjusted p-value
Abcd3^em1(IMPC)J -/-	0.010236	0.0021572	2.1109	0.130	0.0178
Abhd17b^em1(IMPC)J -/-	0.0013250	0.0019222	0.43871	0.742	0.499
Acadsb^em1(IMPC)J -/-	-0.0013977	0.0015975	-0.39120	0.718	0.390
Acy1^em1(IMPC)J -/-	-0.0035174	0.0027148	-0.93881	0.524	0.216
Adad2^em1(IMPC)J -/-	-0.0017286	0.0013657	-0.48724	0.524	0.214
Adamts14^em1(IMPC)J -/-	0.0022003	0.0022093	0.69516	0.742	0.501
Adamtsl4^em1(IMPC)J -/-	0.00035327	0.0024710	0.20857	0.920	0.888
Afmid^em1Llp -/-	-0.0019578	0.0014699	-0.53695	0.504	0.194
Agbl1^em1(IMPC)J/Mmjax -/-	-0.0096373	0.0022580	-2.1109	0.0107	0.000376
Alg8^em1(IMPC)J/Mmjax -/+	-0.0053973	0.0014582	-1.5475	0.265	0.0659
Alg9^em1(IMPC)J/Mmjax -/+	0.0016278	0.0021710	0.56230	0.742	0.464
Ano8^em1(IMPC)J -/-	0.0011227	0.0023446	0.39120	0.816	0.637
Apmap^em1(IMPC)J/Mmjax -/-	-0.0043097	0.0014385	-1.1663	0.0579	0.00610
Arap3^em1(IMPC)J -/-	0.0016213	0.0013384	0.53695	0.543	0.237
AU040320^em1(IMPC)J -/-	0.0036691	0.0020918	1.1663	0.302	0.0927
Brip1^em1(IMPC)J/Mmjax -/-	0.0034051	0.0041329	1.0458	0.742	0.425
C1qc^em1(IMPC)J -/-	-0.0015152	0.0025101	-0.41484	0.758	0.552
C7^em1(IMPC)J/Mmjax -/-	-0.0015538	0.0022661	-0.43871	0.742	0.501
Catsperz^{tm1.1(KOMP)Vlcg} -/-	-0.0012051	0.0014437	-0.32151	0.742	0.411
Ccdc28a^{tm3b(EUCOMM)Wtsi}/2J -/-	0.0041733	0.0017167	1.3597	0.137	0.0205
Cdc42bpb^em1(IMPC)J -/+	-0.0026400	0.0016581	-0.75180	0.373	0.124
Cep135^em1(IMPC)J -/+	0.0039645	0.0034501	1.3067	0.574	0.262
Cgref1^em1(IMPC)J/Mmjax -/-	-0.0028209	0.0019890	-0.81096	0.469	0.170
Chmp7^em1(IMPC)J/Mmjax -/+	0.0032840	0.0028139	1.0089	0.742	0.451
Cldn13^em1(IMPC)J -/-	0.0051109	0.0014942	1.4790	0.0386	0.00271
Clptm1l^em1(IMPC)J/Mmjax -/-	-0.0025351	0.0018147	-0.69516	0.469	0.177
Cr2^em1Llp -/-	-0.0027757	0.0016737	-0.78103	0.334	0.108
Diaph3^{tm1b(KOMP)Mbp}/2J -/+	0.0038937	0.0019301	1.2572	0.252	0.0566
Dnajb2^em1(IMPC)J -/-	0.0017698	0.0016676	0.58802	0.627	0.301
Dnase1l2^em1(IMPC)J -/-	0.0022447	0.0014798	0.75180	0.408	0.142
Drc7^em1(IMPC)J -/-	-0.0020874	0.0017401	-0.58802	0.543	0.243
Eef1b2^em1(IMPC)J/Mmjax -/-	0.0014848	0.0027028	0.48724	0.765	0.589
Egfem1^em1(IMPC)J -/-	-0.00060209	0.0030651	-0.076363	0.920	0.862
Fbxo10^em1(IMPC)J/Mmjax -/-	-0.0011959	0.0019649	-0.29864	0.758	0.550
Fkbp6^{tm1b(KOMP)Wtsi} -/-	-0.00041576	0.0018088	-0.054519	0.871	0.820
Frmpd1^em1(IMPC)J -/-	0.0025010	0.0032552	0.90547	0.754	0.523
Gm20498^em1(IMPC)J/Mmjax -/-	-0.00076006	0.0013415	-0.20857	0.765	0.578
Gpr15^em1(IMPC)J -/-	-0.0087185	0.0019580	-1.9417	0.00928	0.000244
Gramd3^em1(IMPC)J/Mmjax -/-	0.0026339	0.0018637	0.93881	0.506	0.170
Gsto1^em1(IMPC)J/Mmjax -/-	-0.0062553	0.0027086	-1.8147	0.177	0.0295
Gtpbp10^{tm1b(KOMP)Mbp} -/-	0.00021612	0.0022006	0.18635	0.939	0.923
Hipk4^{tm1b(KOMP)Mbp} -/-	-0.0033753	0.0018275	-0.87310	0.272	0.0757
Hlcs^em1(IMPC)J/Mmjax -/+	0.00076911	0.0019121	0.32151	0.860	0.694
Idh3b^em1(IMPC)J/Mmjax -/-	-0.00074179	0.0012500	-0.18635	0.761	0.561
Igsf11^{tm1b(KOMP)Wtsi} -/-	-0.0046912	0.0022830	-1.3067	0.252	0.0520
Kcnc3^em1(IMPC)J -/-	-0.0013424	0.0017247	-0.34455	0.742	0.443
Klhl22^em1(IMPC)J/Mmjax -/-	-0.0037057	0.0015566	-0.97324	0.164	0.0259
Krt80^em1(IMPC)J -/-	0.0022319	0.0013365	0.72319	0.334	0.108
Lpgat1^em1(IMPC)J/Mmjax -/-	-0.00020936	0.0018123	0.12017	0.934	0.909
Lrp1^{tm1.1(KOMP)Wtsi} -/+	0.00096729	0.0027142	0.34455	0.871	0.726
Mapk15^{tm1b(EUCOMM)Hmgu} -/-	0.0035519	0.0019056	1.0842	0.272	0.0764
Mfsd4b4^em1(IMPC)J/Mmjax -/-	-0.00017127	0.0021909	0.14216	0.947	0.938
Mgme1^em1(IMPC)J/Mmjax -/-	0.0087431	0.0012412	1.9417	0.000769	0.0000135
Mlx^{tm1.1(KOMP)Vlcg} -/-	-0.0034976	0.0028499	-0.90547	0.543	0.230
Mmaa^em1(IMPC)J/Mmjax -/-	0.0057314	0.010301	1.5475	0.765	0.590
Nars2^em1(IMPC)J -/+	-0.0010648	0.0014796	-0.23090	0.758	0.546
Nt5dc2^em1(IMPC)J/Mmjax -/-	0.0023978	0.0011895	0.87310	0.265	0.0650
Nup37^{tm1.1(KOMP)Vlcg}/2J -/-	-0.0043080	0.0027889	-1.1243	0.408	0.143
Ofcc1^em1(IMPC)J -/-	-0.0045249	0.0023703	-1.2572	0.265	0.0674
Otogl^em1(IMPC)J -/-	-0.0020034	0.0014349	-0.56230	0.469	0.174
Ovch2^{tm1b(KOMP)Mbp} -/-	-0.0044676	0.0015834	-1.3597	0.0503	0.00792
Patj^em1(IMPC)J -/-	0.0023112	0.0039751	0.78103	0.763	0.569
Pcgf1^{tm1.1(KOMP)Vlcg} -/+	-0.00062962	0.0019244	-0.010899	0.920	0.747
Phkb^em1(IMPC)J/Mmjax -/+	0.0019125	0.0030856	0.61413	0.758	0.542
Polr1c^em1(IMPC)J/Mmjax -/+	0.0062319	0.0014083	1.7117	0.0386	0.000165
Prss2^{tm1.1(KOMP)Vlcg} -/-	-0.0013282	0.0014839	-0.72319	0.288	0.379
Ptprk^em1(IMPC)J/Mmjax -/-	-0.00071667	0.0021894	-0.16421	0.871	0.748
Pus1^em1(IMPC)J/Mmjax -/-	-0.0010809	0.0015775	-0.27592	0.742	0.500
Rad21l^{tm1b(KOMP)Wtsi} -/-	0.0010258	0.0015502	0.36777	0.750	0.513
Rec8^{tm1b(KOMP)Wtsi}/2J -/-	-0.0043635	0.0014244	-1.2105	0.0503	0.00441
Rgs22^{tm1b(KOMP)Wtsi} -/-	0.000070849	0.0022892	0.076363	0.920	0.976
Rimklb^{tm1.1(KOMP)Vlcg} -/-	-0.0024980	0.0026053	-0.64067	0.678	0.350
Rnf10^em1(IMPC)J -/-	-0.00028991	0.0017890	0.098243	0.920	0.873
Sebox^em1(IMPC)J -/-	0.0023741	0.0020865	0.81096	0.574	0.267
Secisbp2l^em1(IMPC)J/Mmjax -/-	0.0076290	0.0019577	1.8147	0.0107	0.000467
Sel1l3^em1(IMPC)J/Mmjax -/-	-0.0051607	0.0031748	-1.4790	0.678	0.351
Serpina1f^em1(IMPC)J -/-	0.0023766	0.0023286	0.84162	0.647	0.324
Setd6^{tm1.1(KOMP)Mbp}/3J -/-	-0.00050973	0.0030669	-0.032701	0.920	0.869
Sh3rf3^em1(IMPC)J/Mmjax -/-	-0.00061383	0.0014352	-0.098243	0.849	0.672
Slc41a2^em1(IMPC)J/Mmjax -/-	-0.000021067	0.0022307	0.16421	0.993	0.993
Slc9a9^em1(IMPC)J/Mmjax -/-	0.0021228	0.0023517	0.66766	0.702	0.376
Snx3^{tm1.1(KOMP)Vlcg} -/+	0.0011375	0.0016394	0.41484	0.742	0.494
Sp5^{tm1b(KOMP)Wtsi} -/-	0.00061405	0.0016157	0.29864	0.868	0.708
Spag17^{tm1b(KOMP)Wtsi} -/-	-0.00066406	0.0020432	-0.14216	0.871	0.748
Spink12^em1(IMPC)J -/-	-0.0049368	0.0018596	-1.4169	0.113	0.0139
Sprr1a^em1(IMPC)J -/-	-0.0018715	0.0017625	-0.51194	0.627	0.302
Srbd1^em1(IMPC)J/Mmjax -/+	0.00060072	0.0019074	0.27592	0.918	0.806
St6galnac3^em1(IMPC)J -/-	-0.0059426	0.0028336	-1.7117	0.252	0.0533
Stag3^{tm1e.1(KOMP)Wtsi}/2J -/-	-0.0039686	0.0015941	-1.0458	0.130	0.0182
Svep1^{tm1b(EUCOMM)Hmgu} -/+	-0.0010799	0.0015310	-0.25335	0.742	0.489
Syce1^{tm1b(KOMP)Wtsi}/2J -/-	0.0016000	0.0015609	0.51194	0.636	0.312
Taco1^em1(IMPC)J/Mmjax -/-	-0.00063630	0.0018400	0.25335	0.918	0.732
Tat^em1(IMPC)J/Mmjax -/-	0.0014145	0.0030858	0.46284	0.849	0.651
Tbc1d5^em1(IMPC)J -/-	0.0019245	0.0025240	0.64067	0.742	0.457
Tctn3^em1(IMPC)J/Mmjax -/+	-0.0037642	0.00086092	-1.0089	0.0121	0.000638
Tecpr2^em1(IMPC)J/Mmjax -/-	0.0038913	0.0020328	1.2105	0.272	0.0726
Tex2^{tm1.1(KOMP)Vlcg}/2J -/-	-0.0042330	0.0013581	-1.0842	0.0521	0.00502
Thsd7a^{tm1b(KOMP)Mbp} -/-	0.00041946	0.0014569	0.23090	0.893	0.776
Tnnc1^em1(IMPC)J/Mmjax -/+	-0.00035654	0.0018606	0.054519	0.920	0.849
Tpgs2^{tm1.1(KOMP)Vlcg} -/-	0.94291	1.3373	2.3783	0.742	0.486
Trf^em1(IMPC)J/Mmjax -/+	-0.00038257	0.0017927	0.032701	0.920	0.833
Trip13^{tm1.1(KOMP)Vlcg} -/-	-0.0050598	0.0022193	-1.6241	0.177	0.0307
Tspan13^em1Llp -/-	-0.00065822	0.0018488	-0.12017	0.871	0.725
Ttc38^em1Llp -/-	-0.011557	0.0018025	-2.3783	0.000338	0.00000296
Ubap2^em1(IMPC)J/Mmjax -/-	-0.0016911	0.0021745	-0.46284	0.742	0.444
Wdr81^em1(IMPC)J -/+	0.0028846	0.0016481	0.97324	0.302	0.0919
Yeats2^em1(IMPC)J/Mmjax -/+	0.00020397	0.0021975	0.010899	0.920	0.927
Zc3h7a^em1(IMPC)J/Mmjax -/-	-0.0031753	0.0014687	-0.84162	0.209	0.0404
Zfp174^em1(IMPC)J -/-	-0.0022875	0.0024492	-0.61413	0.683	0.360
Zfp329^em1(IMPC)J -/-	-0.0025060	0.0012537	-0.66766	0.252	0.0576
Zfp422^em1(IMPC)J -/-	0.0035771	0.0016338	1.1243	0.207	0.0381
Zfp706^em1(IMPC)J/Mmjax -/+	-0.0013670	0.0019768	-0.36777	0.742	0.496
Zfp827^em1(IMPC)J/Mmjax -/+	0.0043851	0.0034882	1.4169	0.543	0.240
Zfp827^em1(IMPC)J/Mmjax -/-	0.0059974	0.0019023	1.6241	0.102	0.0117

TRAIT CORRELATION PLOT

Correlate ratio of soft-tissue attenuation coefficients with JaxKOMP-LAP trait: