MPD: JaxKOMP-EAP genotype: Sae1<sup>em1(IMPC)J</sup>/Mmjax -/+

JaxKOMP-EAP effect sizes: Sae1^em1(IMPC)J/Mmjax -/+ Gene Sae1

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

In this plot, data points are the computed genotype effect size vs. C57BL/6NJ controls, for all measured numeric phenotypes in JaxKOMP-EAP

Dimensions Width: × Height: px

Plot Options Group by Procedure Standard Error Show Effect Sizes RankZ

Significance Threshold p-Value Threshold Adjusted Unadjusted

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Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value

ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	3.8511	4.0010	undefined	undefined	0.361
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	3.3251	2.7451	undefined	undefined	0.257
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	7.6652	8.2751	undefined	undefined	0.376
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	8.4375	5.8233	undefined	undefined	0.178
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	6.9561	7.8358	undefined	undefined	0.398
body composition	body length	-0.052848	0.038818	undefined	undefined	0.184
body composition	body weight (at time of DXA)	-0.54375	0.60924	undefined	undefined	0.379
body composition	bone area, whole body scan, head excluded	0.036343	0.10373	undefined	undefined	0.729
body composition	bone mineral content of whole body scan, head excluded	0.012082	0.010123	undefined	undefined	0.242
body composition	bone mineral content to body weight ratio	0.00053391	0.00037265	undefined	undefined	0.163
body composition	bone mineral density of whole body scan, head excluded	0.0012353	0.00065411	undefined	undefined	0.0690
body composition	fat tissue mass of whole body scan, head excluded	-0.023122	0.36675	undefined	undefined	0.950
body composition	fat tissue mass to body weight ratio	-0.0024536	0.012940	undefined	undefined	0.851
body composition	lean tissue mass of whole body scan, head excluded	0.023168	0.33977	undefined	undefined	0.946
body composition	lean tissue mass to body weight ratio	0.0072950	0.012751	undefined	undefined	0.572
body composition	percent fat, whole body scan, head excluded	-0.21655	1.3514	undefined	undefined	0.874
body composition	ratio of soft-tissue attenuation coefficients	0.21133	0.45930	undefined	undefined	0.649
body composition	tissue area	-0.032649	0.17621	undefined	undefined	0.854
body composition	total tissue mass, whole body scan, head excluded	0.034248	0.18368	undefined	undefined	0.853
clinical blood chemistry	alanine transaminase (plasma ALT)	22.069	19.734	undefined	undefined	0.272
clinical blood chemistry	albumin (plasma Alb)	0.32767	0.43013	undefined	undefined	0.452
clinical blood chemistry	alkaline phosphatase (plasma ALP)	3.8555	2.6236	undefined	undefined	0.152
clinical blood chemistry	aspartate transaminase (plasma AST)	8.1625	11.654	undefined	undefined	0.489
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	-0.17614	0.17415	undefined	undefined	0.320
clinical blood chemistry	blood urea nitrogen (BUN)	-1.5625	1.3354	undefined	undefined	0.251
clinical blood chemistry	calcium (plasma Ca)	0.29152	0.073143	undefined	undefined	0.000397
clinical blood chemistry	creatinine (plasma)	0.020363	0.039830	undefined	undefined	0.613
clinical blood chemistry	glucose (plasma GLU, no fast)	15.325	8.6186	undefined	undefined	0.0855
clinical blood chemistry	HDL cholesterol (plasma HDL)	4.3340	1.9902	undefined	undefined	0.0377
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	0.0057477	0.0077482	undefined	undefined	0.464
clinical blood chemistry	phosphorus (plasma phosphate)	0.55736	0.29540	undefined	undefined	0.0689
clinical blood chemistry	total bilirubin (plasma TBIL)	-0.0011530	0.0073999	undefined	undefined	0.877
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	5.6242	2.8237	undefined	undefined	0.0559
clinical blood chemistry	total protein (plasma TP)	0.96965	0.46507	undefined	undefined	0.0460
clinical blood chemistry	triglyceride (plasma TG, no fast)	-9.9511	9.5687	undefined	undefined	0.307
glucose tolerance test	amount glucose injected	-3.0688	1.7681	undefined	undefined	0.0940
glucose tolerance test	plasma glucose, 0min	-0.24635	4.5193	undefined	undefined	0.957
glucose tolerance test	plasma glucose, 15min	-24.831	15.005	undefined	undefined	0.109
glucose tolerance test	plasma glucose, 30min	-21.529	16.868	undefined	undefined	0.212
glucose tolerance test	plasma glucose, 60min	-7.9572	13.571	undefined	undefined	0.562
glucose tolerance test	plasma glucose, 120min	-1.8442	7.6083	undefined	undefined	0.810
grip strength	body weight (at time of grip strength test)	0.36643	0.57351	undefined	undefined	0.530
grip strength	forelimb and hindlimb grip strength (mean of trials), average	2.2334	5.9217	undefined	undefined	0.710
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	0.056570	0.33109	undefined	undefined	0.866
grip strength	forelimb and hindlimb grip strength by trial, trial1	-2.5389	5.9290	undefined	undefined	0.673
grip strength	forelimb and hindlimb grip strength by trial, trial2	3.2390	7.1802	undefined	undefined	0.657
grip strength	forelimb and hindlimb grip strength by trial, trial3	10.565	8.7274	undefined	undefined	0.241
grip strength	forelimb grip strength (mean of trials), average	-5.4478	6.1517	undefined	undefined	0.386
grip strength	forelimb grip strength (mean of trials), average normalized to bw	-0.29653	0.26639	undefined	undefined	0.280
grip strength	forelimb grip strength by trial, trial1	-2.5686	6.0838	undefined	undefined	0.677
grip strength	forelimb grip strength by trial, trial2	-2.1386	6.8249	undefined	undefined	0.757
grip strength	forelimb grip strength by trial, trial3	-8.3317	6.0338	undefined	undefined	0.183
heart weight	heart weight, normalized to body weight	0.17354	0.091200	undefined	undefined	0.0667
heart weight	heart weight, weight	2.9533	3.2065	undefined	undefined	0.365
hematology	basophil differential (percent of total WBC)	0.054132	0.051669	undefined	undefined	0.303
hematology	eosinophil differential (percent of total WBC)	0.20713	0.34529	undefined	undefined	0.553
hematology	hematocrit (HCT)	-0.26964	0.36354	undefined	undefined	0.464
hematology	lymphocyte differential (percent of total WBC)	-2.3550	0.97811	undefined	undefined	0.0224
hematology	mean corpuscular hemoglobin (CHr)	0.10625	0.058150	undefined	undefined	0.0776
hematology	mean platelet volume (MPV)	0.18165	0.043876	undefined	undefined	0.000259
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	0.054618	0.13198	undefined	undefined	0.682
hematology	mean RBC corpuscular volume (MCV)	0.25375	0.19132	undefined	undefined	0.195
hematology	measured hemoglobin (mHGB)	-0.068750	0.12600	undefined	undefined	0.589
hematology	monocyte differential (percent of total WBC)	0.65650	0.22087	undefined	undefined	0.00578
hematology	neutrophil differential (percent of total WBC)	1.3675	0.63616	undefined	undefined	0.0398
hematology	platelet count (PLT; units per volume x 10³)	-19.913	42.154	undefined	undefined	0.640
hematology	RBC corpuscular distribution width (RDW)	0.15000	0.12503	undefined	undefined	0.240
hematology	red blood cell count (RBC; per volume x 10⁶)	-0.12181	0.086052	undefined	undefined	0.167
hematology	reticulocyte count (Retic; units per volume x 10⁹)	31.786	11.709	undefined	undefined	0.0109
hematology	reticulocyte differential (percent of total RBC)	0.34675	0.11303	undefined	undefined	0.00454
hematology	white blood cell count (WBC; units per volume x 10³)	-0.83172	0.56889	undefined	undefined	0.154
holeboard	number of hole pokes by individual hole number, 20 min test, 1	-1.1405	1.4364	undefined	undefined	0.434
holeboard	number of hole pokes by individual hole number, 20 min test, 2	0.087889	0.58981	undefined	undefined	0.883
holeboard	number of hole pokes by individual hole number, 20 min test, 3	-0.88447	0.47763	undefined	undefined	0.0743
holeboard	number of hole pokes by individual hole number, 20 min test, 4	2.1725	0.98011	undefined	undefined	0.0347
holeboard	number of hole pokes by individual hole number, 20 min test, 5	-0.91861	0.68115	undefined	undefined	0.188
holeboard	number of hole pokes by individual hole number, 20 min test, 6	-0.51239	0.34540	undefined	undefined	0.149
holeboard	number of hole pokes by individual hole number, 20 min test, 7	0.20598	0.48846	undefined	undefined	0.676
holeboard	number of hole pokes by individual hole number, 20 min test, 8	-1.1267	0.81991	undefined	undefined	0.180
holeboard	number of hole pokes by individual hole number, 20 min test, 9	-0.75878	0.50921	undefined	undefined	0.147
holeboard	number of hole pokes by individual hole number, 20 min test, 10	0.43435	0.47194	undefined	undefined	0.365
holeboard	number of hole pokes by individual hole number, 20 min test, 11	-0.64275	0.46183	undefined	undefined	0.175
holeboard	number of hole pokes by individual hole number, 20 min test, 12	-0.28887	0.54009	undefined	undefined	0.597
holeboard	number of hole pokes by individual hole number, 20 min test, 13	-0.81832	1.0952	undefined	undefined	0.461
holeboard	number of hole pokes by individual hole number, 20 min test, 14	-0.73472	0.66721	undefined	undefined	0.280
holeboard	number of hole pokes by individual hole number, 20 min test, 15	0.25421	0.78695	undefined	undefined	0.749
holeboard	number of hole pokes by individual hole number, 20 min test, 16	-1.4020	1.1025	undefined	undefined	0.214
holeboard	total number of hole pokes, 20 min test	-6.0059	6.7042	undefined	undefined	0.378
light / dark	latency to enter dark zone, 20 min test	55.927	70.023	undefined	undefined	0.431
light / dark	number of transitions between light and dark zones, 20 min test	-13.934	6.8782	undefined	undefined	0.0518
light / dark	percentage of total time in dark zone, 20 min test	1.6562	5.0310	undefined	undefined	0.744
light / dark	percentage of total time in light zone, 20 min test	-1.6562	5.0310	undefined	undefined	0.744
light / dark	time mobile in dark zone, 20 min test	-9.1833	4.3928	undefined	undefined	0.0454
light / dark	time mobile in light zone, 20 min test	-2.6968	5.1649	undefined	undefined	0.606
light / dark	time spent in dark zone, 20 min test	-23.194	51.086	undefined	undefined	0.653
light / dark	time spent in light zone, 20 min test	23.194	51.086	undefined	undefined	0.653
open field	average speed in center of arena, 20 min test	-0.59887	0.42738	undefined	undefined	0.171
open field	average speed in periphery of arena, 20 min test	-0.40737	0.17824	undefined	undefined	0.0295
open field	distance traveled habituation ratio, 20 min test	7.2291	8.0485	undefined	undefined	0.376
open field	distance traveled in center of arena, 20 min test	-359.47	149.12	undefined	undefined	0.0223
open field	distance traveled in periphery of arena, 20 min test	-245.49	144.96	undefined	undefined	0.101
open field	distance traveled slope, 20 min test	5.5371	7.8751	undefined	undefined	0.487
open field	distance traveled, 20 min test, 1st 5min	-211.08	91.255	undefined	undefined	0.0278
open field	distance traveled, 20 min test, 2nd 5min	-119.78	71.230	undefined	undefined	0.103
open field	distance traveled, 20 min test, 3rd 5min	-149.68	76.516	undefined	undefined	0.0598
open field	distance traveled, 20 min test, 4th 5min	-145.59	57.510	undefined	undefined	0.0168
open field	number of clockwise revolution episodes, 20 min test	-2.5250	1.2659	undefined	undefined	0.0552
open field	number of counter-clockwise revolution episodes, 20 min test	-1.4750	1.6294	undefined	undefined	0.373
open field	number of rears in 5 min bins, 20 min test, 1st 5min	-3.4750	2.6582	undefined	undefined	0.201
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	-5.2875	3.6195	undefined	undefined	0.154
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	-7.7644	3.0001	undefined	undefined	0.0147
open field	number of rears in 5 min bins, 20 min test, 4th 5min	-8.1683	3.4066	undefined	undefined	0.0232
open field	percentage of total time in center of arena, 20 min test	-1.9362	3.2764	undefined	undefined	0.559
open field	percentage of total time in center of arena, slope, 20 min test	-2.5209	2.1342	undefined	undefined	0.247
open field	percentage of total time in center, habituation ratio, 20 min test	-3.0997	2.3764	undefined	undefined	0.202
open field	percentage of total time in corners of arena, 20 min test	5.8039	3.1481	undefined	undefined	0.0751
open field	percentage of total time in corners, habituation ratio, 20 min test	-0.19638	2.3091	undefined	undefined	0.933
open field	percentage of total time in corners, slope, 20 min test	-0.65175	2.1375	undefined	undefined	0.763
open field	permanence time in center of arena, 20 min test	-23.227	39.317	undefined	undefined	0.559
open field	permanence time in corners of arena, 20 min test	69.643	37.774	undefined	undefined	0.0751
open field	permanence time in periphery of arena, 20 min test	23.226	39.317	undefined	undefined	0.559
open field	total distance traveled, 20 min test	-626.69	260.23	undefined	undefined	0.0224
open field	total number of rears, 20 min test	-26.302	10.582	undefined	undefined	0.0187
open field	whole arena average speed, 20 min test	-0.52150	0.21672	undefined	undefined	0.0225
open field	whole arena resting time, 20 min test	72.274	25.327	undefined	undefined	0.00790
open field	whole arena time spent mobile, 20 min test	-14.634	5.2032	undefined	undefined	0.00858
open field	whole arena time spent vertical, 20 min test	-9.2986	7.6737	undefined	undefined	0.235
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	1.0299	1.7537	undefined	undefined	0.564
startle / PPI	average baseline movement during background noise	1.3605	1.9206	undefined	undefined	0.484
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	0.032215	0.071325	undefined	undefined	0.655
startle / PPI	average of each corrected percent pre-pulse inhibition value	0.010182	0.072687	undefined	undefined	0.890
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	3.8982	7.3688	undefined	undefined	0.601
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-1.9093	8.0626	undefined	undefined	0.814
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	1.8464	7.8307	undefined	undefined	0.815
startle / PPI	average startle response to full pulse (120 dB)	-11.322	45.112	undefined	undefined	0.804
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-18.538	51.395	undefined	undefined	0.721
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	18.692	50.359	undefined	undefined	0.713
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-6.7936	48.844	undefined	undefined	0.890
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	-0.92500	1.4390	undefined	undefined	0.525
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	-0.76667	2.2953	undefined	undefined	0.741
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	0.56001	1.5062	undefined	undefined	0.713
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.032236	0.077989	undefined	undefined	0.682
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.053037	0.084157	undefined	undefined	0.533
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.016789	0.085677	undefined	undefined	0.846
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	-12.675	45.244	undefined	undefined	0.781
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	-17.464	51.472	undefined	undefined	0.737
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	19.948	49.699	undefined	undefined	0.691
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	-6.9539	48.961	undefined	undefined	0.888
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.062696	0.080554	undefined	undefined	0.442
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.026247	0.081032	undefined	undefined	0.748
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.053052	0.085503	undefined	undefined	0.540
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	-57.974	169.64	undefined	undefined	0.735
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	-48.496	187.67	undefined	undefined	0.798
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	58.531	184.09	undefined	undefined	0.753
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	-62.094	187.38	undefined	undefined	0.743
startle / PPI	maximum baseline movement during background noise	1.2126	3.9357	undefined	undefined	0.760
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	6.5871	7.7698	undefined	undefined	0.403
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-2.0422	7.8408	undefined	undefined	0.796
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	5.0874	7.9592	undefined	undefined	0.528
startle / PPI	maximum startle response to full pulse (120 dB)	-56.460	168.98	undefined	undefined	0.741
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-52.563	187.41	undefined	undefined	0.781
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	55.787	185.42	undefined	undefined	0.766
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-61.886	187.15	undefined	undefined	0.743
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	-3.4750	3.4138	undefined	undefined	0.317
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	-1.7299	4.7104	undefined	undefined	0.716
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	1.2604	4.1321	undefined	undefined	0.762

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

In this plot, data points are the computed genotype effect % vs. C57BL/6NJ controls, for all measured categorical phenotypes in JaxKOMP-EAP

Dimensions Width: × Height: px

Plot Options Group by Procedure

Include Sexes Data Both Females Males

Significance Threshold p-Value Threshold

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Procedure	JaxKOMP-EAP Trait	Sex	Trait Effect	P-value

eye morphology	anterior chamber depth	females	1.0 %	1.0
eye morphology	anterior chamber depth	males	0.0 %	1.0
eye morphology	anterior chamber depth	both	1.0 %	1.0
eye morphology	bulging eye	females	1.0 %	1.0
eye morphology	bulging eye	males	0.0 %	1.0
eye morphology	bulging eye	both	1.0 %	1.00
eye morphology	cornea	females	4.0 %	1.0
eye morphology	cornea	males	2.0 %	1.0
eye morphology	cornea	both	3.0 %	1.00
eye morphology	cornea opacity	females	5.0 %	1.0
eye morphology	cornea opacity	males	1.0 %	1.0
eye morphology	cornea opacity	both	3.0 %	1.00
eye morphology	cornea vascularization	females	3.0 %	1.0
eye morphology	cornea vascularization	males	1.0 %	1.0
eye morphology	cornea vascularization	both	2.0 %	1.00
eye morphology	corneal deposits	females	2.0 %	1.0
eye morphology	corneal deposits	males	1.0 %	1.0
eye morphology	corneal deposits	both	1.0 %	1.00
eye morphology	corneal mineralization	females	2.0 %	1.0
eye morphology	corneal mineralization	males	1.0 %	1.0
eye morphology	corneal mineralization	both	1.0 %	1.00
eye morphology	corneal scleralization	females	3.0 %	1.0
eye morphology	corneal scleralization	males	1.0 %	1.0
eye morphology	corneal scleralization	both	2.0 %	1.00
eye morphology	corneal ulcer	females	1.0 %	1.0
eye morphology	corneal ulcer	males	1.0 %	1.0
eye morphology	corneal ulcer	both	1.0 %	1.00
eye morphology	eye closure	females	1.0 %	1.0
eye morphology	eye closure	males	0.0 %	1.0
eye morphology	eye closure	both	1.0 %	1.00
eye morphology	eye hemorrhage or blood presence	females	2.0 %	1.0
eye morphology	eye hemorrhage or blood presence	males	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	both	1.0 %	1.00
eye morphology	eyelid morphology	females	1.0 %	1.00
eye morphology	eyelid morphology	males	0.0 %	1.0
eye morphology	eyelid morphology	both	1.0 %	1.00
eye morphology	eyes (present, absent)	females	1.0 %	1.00
eye morphology	eyes (present, absent)	males	0.0 %	1.0
eye morphology	eyes (present, absent)	both	0.0 %	1.00
eye morphology	fusion between cornea and lens	females	4.0 %	1.0
eye morphology	fusion between cornea and lens	males	2.0 %	1.0
eye morphology	fusion between cornea and lens	both	3.0 %	1.00
eye morphology	iris pigmentation	females	2.0 %	1.0
eye morphology	iris pigmentation	males	1.0 %	1.0
eye morphology	iris pigmentation	both	2.0 %	1.00
eye morphology	iris transillumination	females	2.0 %	1.0
eye morphology	iris transillumination	males	1.0 %	1.00
eye morphology	iris transillumination	both	1.0 %	1.00
eye morphology	irispupil	females	4.0 %	1.0
eye morphology	irispupil	males	19.0 %	0.0800
eye morphology	irispupil	both	9.0 %	0.197
eye morphology	lacrimation	females	3.0 %	1.0
eye morphology	lacrimation	males	2.0 %	1.0
eye morphology	lacrimation	both	3.0 %	1.00
eye morphology	lens	females	10.0 %	1.0
eye morphology	lens	males	8.0 %	1.00
eye morphology	lens	both	9.0 %	1.00
eye morphology	lens opacity	females	18.0 %	0.199
eye morphology	lens opacity	males	6.0 %	1.0
eye morphology	lens opacity	both	9.0 %	0.299
eye morphology	narrow eye opening	females	2.0 %	1.00
eye morphology	narrow eye opening	males	1.0 %	1.0
eye morphology	narrow eye opening	both	1.0 %	1.00
eye morphology	optic disc	females	4.0 %	1.0
eye morphology	optic disc	males	2.0 %	1.0
eye morphology	optic disc	both	3.0 %	1.00
eye morphology	persistence of hyaloid vascular system	females	38.0 %	0.0537
eye morphology	persistence of hyaloid vascular system	males	5.0 %	1.0
eye morphology	persistence of hyaloid vascular system	both	18.0 %	0.0941
eye morphology	pupil dilation	females	2.0 %	1.0
eye morphology	pupil dilation	males	1.0 %	1.0
eye morphology	pupil dilation	both	2.0 %	1.00
eye morphology	pupil light response	females	2.0 %	1.0
eye morphology	pupil light response	males	1.0 %	1.0
eye morphology	pupil light response	both	2.0 %	1.00
eye morphology	pupil position	females	4.0 %	1.0
eye morphology	pupil position	males	19.0 %	0.0803
eye morphology	pupil position	both	9.0 %	0.210
eye morphology	pupil shape	females	3.0 %	1.0
eye morphology	pupil shape	males	2.0 %	1.0
eye morphology	pupil shape	both	3.0 %	1.00
eye morphology	retina	females	10.0 %	1.00
eye morphology	retina	males	17.0 %	0.298
eye morphology	retina	both	8.0 %	0.509
eye morphology	retinal blood vessels	females	4.0 %	1.0
eye morphology	retinal blood vessels	males	2.0 %	1.0
eye morphology	retinal blood vessels	both	3.0 %	1.00
eye morphology	retinal blood vessels pattern	females	5.0 %	1.0
eye morphology	retinal blood vessels pattern	males	2.0 %	1.00
eye morphology	retinal blood vessels pattern	both	4.0 %	1.00
eye morphology	retinal blood vessels structure	females	4.0 %	1.0
eye morphology	retinal blood vessels structure	males	2.0 %	1.0
eye morphology	retinal blood vessels structure	both	3.0 %	1.00
eye morphology	retinal pigmentation	females	12.0 %	1.00
eye morphology	retinal pigmentation	males	14.0 %	1.0
eye morphology	retinal pigmentation	both	13.0 %	1.00
eye morphology	retinal structure	females	4.0 %	1.0
eye morphology	retinal structure	males	2.0 %	1.00
eye morphology	retinal structure	both	3.0 %	1.00
eye morphology	synechia	females	4.0 %	1.0
eye morphology	synechia	males	2.0 %	1.0
eye morphology	synechia	both	3.0 %	1.00
eye morphology	vitreous	females	4.0 %	1.0
eye morphology	vitreous	males	2.0 %	1.0
eye morphology	vitreous	both	3.0 %	1.00
SHIRPA	activity body position	females	1.0 %	1.0
SHIRPA	activity body position	males	2.0 %	1.0
SHIRPA	activity body position	both	1.0 %	1.00
SHIRPA	aggression	females	0.0 %	1.00
SHIRPA	aggression	males	12.0 %	0.0522
SHIRPA	aggression	both	6.0 %	0.0878
SHIRPA	body length	females	0.0 %	1.0
SHIRPA	body length	males	0.0 %	1.00
SHIRPA	body length	both	0.0 %	1.00
SHIRPA	body position	females	0.0 %	1.0
SHIRPA	body position	males	1.0 %	1.0
SHIRPA	body position	both	0.0 %	1.0
SHIRPA	body thickness	females	1.0 %	1.0
SHIRPA	body thickness	males	0.0 %	1.0
SHIRPA	body thickness	both	0.0 %	1.0
SHIRPA	coat color abdomen	females	3.0 %	1.00
SHIRPA	coat color abdomen	males	4.0 %	1.0
SHIRPA	coat color abdomen	both	4.0 %	1.0
SHIRPA	coat color back	females	0.0 %	1.0
SHIRPA	coat color back	males	0.0 %	1.00
SHIRPA	coat color back	both	0.0 %	1.00
SHIRPA	coat color head	females	0.0 %	1.0
SHIRPA	coat color head	males	0.0 %	1.00
SHIRPA	coat color head	both	0.0 %	1.0
SHIRPA	coat color pattern abdomen	females	1.0 %	1.0
SHIRPA	coat color pattern abdomen	males	1.0 %	1.0
SHIRPA	coat color pattern abdomen	both	1.0 %	1.0
SHIRPA	coat color pattern back	females	0.0 %	1.0
SHIRPA	coat color pattern back	males	0.0 %	1.00
SHIRPA	coat color pattern back	both	0.0 %	1.0
SHIRPA	coat color pattern head	females	0.0 %	1.0
SHIRPA	coat color pattern head	males	0.0 %	1.0
SHIRPA	coat color pattern head	both	0.0 %	1.00
SHIRPA	coat hair abdomen texture appearance	females	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	males	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	both	2.0 %	1.0
SHIRPA	coat hair back texture appearance	females	0.0 %	1.0
SHIRPA	coat hair back texture appearance	males	0.0 %	1.0
SHIRPA	coat hair back texture appearance	both	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	females	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	males	1.0 %	1.00
SHIRPA	coat hair distribution abdomen	both	1.0 %	1.00
SHIRPA	coat hair distribution back	females	0.0 %	1.0
SHIRPA	coat hair distribution back	males	0.0 %	1.0
SHIRPA	coat hair distribution back	both	0.0 %	1.0
SHIRPA	coat hair distribution head	females	1.0 %	1.00
SHIRPA	coat hair distribution head	males	1.0 %	1.0
SHIRPA	coat hair distribution head	both	1.0 %	1.0
SHIRPA	coat hair head texture appearance	females	0.0 %	1.00
SHIRPA	coat hair head texture appearance	males	0.0 %	1.0
SHIRPA	coat hair head texture appearance	both	0.0 %	1.0
SHIRPA	contact righting	females	5.0 %	1.0
SHIRPA	contact righting	males	5.0 %	1.00
SHIRPA	contact righting	both	5.0 %	1.00
SHIRPA	ear morphology	females	0.0 %	1.0
SHIRPA	ear morphology	males	0.0 %	1.0
SHIRPA	ear morphology	both	0.0 %	1.0
SHIRPA	fat distribution	females	0.0 %	1.0
SHIRPA	fat distribution	males	0.0 %	1.0
SHIRPA	fat distribution	both	0.0 %	1.00
SHIRPA	forelimb digit number	females	0.0 %	1.00
SHIRPA	forelimb digit number	males	0.0 %	1.0
SHIRPA	forelimb digit number	both	0.0 %	1.00
SHIRPA	forelimb digit position	females	0.0 %	1.0
SHIRPA	forelimb digit position	males	0.0 %	1.0
SHIRPA	forelimb digit position	both	0.0 %	1.0
SHIRPA	forelimb digit shape	females	0.0 %	1.0
SHIRPA	forelimb digit shape	males	0.0 %	1.0
SHIRPA	forelimb digit shape	both	0.0 %	1.0
SHIRPA	forelimb digit size	females	0.0 %	1.0
SHIRPA	forelimb digit size	males	0.0 %	1.0
SHIRPA	forelimb digit size	both	0.0 %	1.0
SHIRPA	forelimb footpads	females	0.0 %	1.0
SHIRPA	forelimb footpads	males	0.0 %	1.0
SHIRPA	forelimb footpads	both	0.0 %	1.0
SHIRPA	forelimb nail length	females	0.0 %	1.0
SHIRPA	forelimb nail length	males	0.0 %	1.0
SHIRPA	forelimb nail length	both	0.0 %	1.0
SHIRPA	forelimb nail number	females	0.0 %	1.0
SHIRPA	forelimb nail number	males	0.0 %	1.0
SHIRPA	forelimb nail number	both	0.0 %	1.0
SHIRPA	forelimb nail position	females	0.0 %	1.0
SHIRPA	forelimb nail position	males	0.0 %	1.0
SHIRPA	forelimb nail position	both	0.0 %	1.0
SHIRPA	forelimb nail shape	females	0.0 %	1.0
SHIRPA	forelimb nail shape	males	0.0 %	1.0
SHIRPA	forelimb nail shape	both	0.0 %	1.0
SHIRPA	forelimbs position	females	0.0 %	1.0
SHIRPA	forelimbs position	males	0.0 %	1.0
SHIRPA	forelimbs position	both	0.0 %	1.0
SHIRPA	forelimbs shape	females	0.0 %	1.0
SHIRPA	forelimbs shape	males	0.0 %	1.0
SHIRPA	forelimbs shape	both	0.0 %	1.0
SHIRPA	forelimbs size	females	0.0 %	1.0
SHIRPA	forelimbs size	males	0.0 %	1.0
SHIRPA	forelimbs size	both	0.0 %	1.0
SHIRPA	forepaw position	females	0.0 %	1.0
SHIRPA	forepaw position	males	0.0 %	1.0
SHIRPA	forepaw position	both	0.0 %	1.0
SHIRPA	forepaw shape	females	0.0 %	1.0
SHIRPA	forepaw shape	males	0.0 %	1.0
SHIRPA	forepaw shape	both	0.0 %	1.0
SHIRPA	forepaw size	females	0.0 %	1.0
SHIRPA	forepaw size	males	0.0 %	1.0
SHIRPA	forepaw size	both	0.0 %	1.0
SHIRPA	gait (fluidity)	females	0.0 %	1.0
SHIRPA	gait (fluidity)	males	0.0 %	1.00
SHIRPA	gait (fluidity)	both	0.0 %	1.00
SHIRPA	genitalia morphology	females	0.0 %	1.00
SHIRPA	genitalia morphology	males	0.0 %	1.0
SHIRPA	genitalia morphology	both	0.0 %	1.00
SHIRPA	genitalia presence	females	0.0 %	1.0
SHIRPA	genitalia presence	males	0.0 %	1.0
SHIRPA	genitalia presence	both	0.0 %	1.0
SHIRPA	genitalia size	females	0.0 %	1.0
SHIRPA	genitalia size	males	0.0 %	1.0
SHIRPA	genitalia size	both	0.0 %	1.0
SHIRPA	head bobbing	females	0.0 %	1.0
SHIRPA	head bobbing	males	0.0 %	1.0
SHIRPA	head bobbing	both	0.0 %	1.0
SHIRPA	head morphology	females	0.0 %	1.0
SHIRPA	head morphology	males	0.0 %	1.00
SHIRPA	head morphology	both	0.0 %	1.0
SHIRPA	head size	females	0.0 %	1.0
SHIRPA	head size	males	0.0 %	1.0
SHIRPA	head size	both	0.0 %	1.00
SHIRPA	hindlimb digit number	females	1.0 %	1.00
SHIRPA	hindlimb digit number	males	0.0 %	1.0
SHIRPA	hindlimb digit number	both	0.0 %	1.00
SHIRPA	hindlimb digit position	females	0.0 %	1.0
SHIRPA	hindlimb digit position	males	0.0 %	1.0
SHIRPA	hindlimb digit position	both	0.0 %	1.0
SHIRPA	hindlimb digit shape	females	0.0 %	1.0
SHIRPA	hindlimb digit shape	males	0.0 %	1.0
SHIRPA	hindlimb digit shape	both	0.0 %	1.0
SHIRPA	hindlimb digit size	females	0.0 %	1.00
SHIRPA	hindlimb digit size	males	0.0 %	1.0
SHIRPA	hindlimb digit size	both	0.0 %	1.00
SHIRPA	hindlimb nail length	females	0.0 %	1.0
SHIRPA	hindlimb nail length	males	0.0 %	1.0
SHIRPA	hindlimb nail length	both	0.0 %	1.00
SHIRPA	hindlimb nail number	females	0.0 %	1.0
SHIRPA	hindlimb nail number	males	1.0 %	1.0
SHIRPA	hindlimb nail number	both	0.0 %	1.00
SHIRPA	hindlimb nail position	females	0.0 %	1.0
SHIRPA	hindlimb nail position	males	0.0 %	1.0
SHIRPA	hindlimb nail position	both	0.0 %	1.0
SHIRPA	hindlimb nail shape	females	0.0 %	1.0
SHIRPA	hindlimb nail shape	males	0.0 %	1.0
SHIRPA	hindlimb nail shape	both	0.0 %	1.0
SHIRPA	hindlimbs footpads	females	0.0 %	1.0
SHIRPA	hindlimbs footpads	males	0.0 %	1.0
SHIRPA	hindlimbs footpads	both	0.0 %	1.0
SHIRPA	hindlimbs position	females	0.0 %	1.0
SHIRPA	hindlimbs position	males	0.0 %	1.0
SHIRPA	hindlimbs position	both	0.0 %	1.0
SHIRPA	hindlimbs shape	females	0.0 %	1.0
SHIRPA	hindlimbs shape	males	0.0 %	1.0
SHIRPA	hindlimbs shape	both	0.0 %	1.0
SHIRPA	hindlimbs size	females	0.0 %	1.0
SHIRPA	hindlimbs size	males	0.0 %	1.0
SHIRPA	hindlimbs size	both	0.0 %	1.0
SHIRPA	hindpaw position	females	0.0 %	1.0
SHIRPA	hindpaw position	males	0.0 %	1.0
SHIRPA	hindpaw position	both	0.0 %	1.0
SHIRPA	hindpaw shape	females	0.0 %	1.0
SHIRPA	hindpaw shape	males	0.0 %	1.0
SHIRPA	hindpaw shape	both	0.0 %	1.0
SHIRPA	hindpaw size	females	0.0 %	1.0
SHIRPA	hindpaw size	males	0.0 %	1.0
SHIRPA	hindpaw size	both	0.0 %	1.0
SHIRPA	limb grasp	females	9.0 %	1.00
SHIRPA	limb grasp	males	6.0 %	1.0
SHIRPA	limb grasp	both	7.0 %	0.624
SHIRPA	lower lip morphology	females	0.0 %	1.0
SHIRPA	lower lip morphology	males	0.0 %	1.0
SHIRPA	lower lip morphology	both	0.0 %	1.0
SHIRPA	lower teeth appearance	females	0.0 %	1.0
SHIRPA	lower teeth appearance	males	0.0 %	1.00
SHIRPA	lower teeth appearance	both	0.0 %	1.00
SHIRPA	mouth morphology	females	0.0 %	1.0
SHIRPA	mouth morphology	males	0.0 %	1.00
SHIRPA	mouth morphology	both	0.0 %	1.00
SHIRPA	salivation	females	0.0 %	1.0
SHIRPA	salivation	males	0.0 %	1.0
SHIRPA	salivation	both	0.0 %	1.0
SHIRPA	skin color back paws	females	0.0 %	1.0
SHIRPA	skin color back paws	males	0.0 %	1.0
SHIRPA	skin color back paws	both	0.0 %	1.0
SHIRPA	skin color ear	females	0.0 %	1.0
SHIRPA	skin color ear	males	0.0 %	1.0
SHIRPA	skin color ear	both	0.0 %	1.0
SHIRPA	skin color front paws	females	0.0 %	1.0
SHIRPA	skin color front paws	males	0.0 %	1.0
SHIRPA	skin color front paws	both	0.0 %	1.0
SHIRPA	skin color snout	females	0.0 %	1.0
SHIRPA	skin color snout	males	0.0 %	1.0
SHIRPA	skin color snout	both	0.0 %	1.0
SHIRPA	skin color tail	females	0.0 %	1.0
SHIRPA	skin color tail	males	0.0 %	1.0
SHIRPA	skin color tail	both	0.0 %	1.0
SHIRPA	skin color whole body	females	0.0 %	1.0
SHIRPA	skin color whole body	males	0.0 %	1.0
SHIRPA	skin color whole body	both	0.0 %	1.0
SHIRPA	skin texture back paw	females	12.0 %	0.00294
SHIRPA	skin texture back paw	males	0.0 %	1.0
SHIRPA	skin texture back paw	both	6.0 %	0.00589
SHIRPA	skin texture ear	females	0.0 %	1.0
SHIRPA	skin texture ear	males	0.0 %	1.0
SHIRPA	skin texture ear	both	0.0 %	1.0
SHIRPA	skin texture front paws	females	0.0 %	1.0
SHIRPA	skin texture front paws	males	0.0 %	1.0
SHIRPA	skin texture front paws	both	0.0 %	1.0
SHIRPA	skin texture snout	females	0.0 %	1.0
SHIRPA	skin texture snout	males	0.0 %	1.0
SHIRPA	skin texture snout	both	0.0 %	1.0
SHIRPA	skin texture tail	females	0.0 %	1.0
SHIRPA	skin texture tail	males	0.0 %	1.0
SHIRPA	skin texture tail	both	0.0 %	1.0
SHIRPA	skin texture whole body	females	0.0 %	1.0
SHIRPA	skin texture whole body	males	0.0 %	1.00
SHIRPA	skin texture whole body	both	0.0 %	1.00
SHIRPA	snout size	females	0.0 %	1.0
SHIRPA	snout size	males	1.0 %	1.0
SHIRPA	snout size	both	0.0 %	1.0
SHIRPA	startle response	females	0.0 %	1.00
SHIRPA	startle response	males	0.0 %	1.00
SHIRPA	startle response	both	0.0 %	1.00
SHIRPA	tail curvature	females	0.0 %	1.00
SHIRPA	tail curvature	males	0.0 %	1.0
SHIRPA	tail curvature	both	0.0 %	1.0
SHIRPA	tail elevation	females	1.0 %	1.00
SHIRPA	tail elevation	males	2.0 %	1.0
SHIRPA	tail elevation	both	1.0 %	1.0
SHIRPA	tail length	females	0.0 %	1.0
SHIRPA	tail length	males	0.0 %	1.0
SHIRPA	tail length	both	0.0 %	1.00
SHIRPA	tail morphology	females	0.0 %	1.00
SHIRPA	tail morphology	males	0.0 %	1.0
SHIRPA	tail morphology	both	0.0 %	1.00
SHIRPA	tail presence	females	0.0 %	1.0
SHIRPA	tail presence	males	0.0 %	1.0
SHIRPA	tail presence	both	0.0 %	1.0
SHIRPA	tail shape	females	0.0 %	1.0
SHIRPA	tail shape	males	0.0 %	1.0
SHIRPA	tail shape	both	0.0 %	1.00
SHIRPA	tail thickness	females	0.0 %	1.0
SHIRPA	tail thickness	males	0.0 %	1.0
SHIRPA	tail thickness	both	0.0 %	1.0
SHIRPA	teeth presence	females	0.0 %	1.0
SHIRPA	teeth presence	males	0.0 %	1.00
SHIRPA	teeth presence	both	0.0 %	1.00
SHIRPA	transfer arousal	females	1.0 %	1.0
SHIRPA	transfer arousal	males	2.0 %	1.00
SHIRPA	transfer arousal	both	1.0 %	1.0
SHIRPA	tremor	females	0.0 %	1.0
SHIRPA	tremor	males	0.0 %	1.0
SHIRPA	tremor	both	0.0 %	1.00
SHIRPA	trunk curl	females	0.0 %	1.00
SHIRPA	trunk curl	males	0.0 %	1.0
SHIRPA	trunk curl	both	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	females	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	males	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	both	0.0 %	1.00
SHIRPA	upper lip morphology	females	0.0 %	1.0
SHIRPA	upper lip morphology	males	0.0 %	1.0
SHIRPA	upper lip morphology	both	0.0 %	1.0
SHIRPA	upper teeth appearance	females	0.0 %	1.0
SHIRPA	upper teeth appearance	males	0.0 %	1.0
SHIRPA	upper teeth appearance	both	0.0 %	1.00
SHIRPA	vibrissae appearance	females	2.0 %	1.0
SHIRPA	vibrissae appearance	males	1.0 %	1.0
SHIRPA	vibrissae appearance	both	1.0 %	1.0
SHIRPA	vibrissae presence	females	2.0 %	1.00
SHIRPA	vibrissae presence	males	1.0 %	1.0
SHIRPA	vibrissae presence	both	2.0 %	1.0
SHIRPA	vocalization	females	2.0 %	1.00
SHIRPA	vocalization	males	2.0 %	1.0
SHIRPA	vocalization	both	2.0 %	1.00

GENOTYPE CORRELATION PLOT

Correlate Sae1^em1(IMPC)J/Mmjax -/+ with genotype: