MPD: JaxKOMP-EAP genotype: Dmwd<sup>em1(IMPC)J</sup>/Mmjax -/-

JaxKOMP-EAP effect sizes: Dmwd^em1(IMPC)J/Mmjax -/- Gene Dmwd

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

In this plot, data points are the computed genotype effect size vs. C57BL/6NJ controls, for all measured numeric phenotypes in JaxKOMP-EAP

Dimensions Width: × Height: px

Plot Options Group by Procedure Standard Error Show Effect Sizes RankZ

Significance Threshold p-Value Threshold Adjusted Unadjusted

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Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value

body composition	body length	0.0077199	0.084912	undefined	undefined	0.928
body composition	body weight (at time of DXA)	-2.7522	0.69495	undefined	undefined	0.000714
body composition	bone area, whole body scan, head excluded	0.23539	0.19044	undefined	undefined	0.231
body composition	bone mineral content of whole body scan, head excluded	0.00036549	0.020894	undefined	undefined	0.986
body composition	bone mineral content to body weight ratio	0.0011822	0.00070122	undefined	undefined	0.107
body composition	bone mineral density of whole body scan, head excluded	-0.0015737	0.0013538	undefined	undefined	0.259
body composition	fat tissue mass of whole body scan, head excluded	-0.084169	0.57376	undefined	undefined	0.885
body composition	fat tissue mass to body weight ratio	0.0025864	0.022829	undefined	undefined	0.911
body composition	lean tissue mass of whole body scan, head excluded	0.14729	0.46387	undefined	undefined	0.754
body composition	lean tissue mass to body weight ratio	0.012730	0.020151	undefined	undefined	0.535
body composition	percent fat, whole body scan, head excluded	-0.048169	1.9802	undefined	undefined	0.981
body composition	ratio of soft-tissue attenuation coefficients	-0.75931	0.99298	undefined	undefined	0.453
body composition	tissue area	-0.23872	0.42674	undefined	undefined	0.582
body composition	total tissue mass, whole body scan, head excluded	0.076884	0.69363	undefined	undefined	0.913
clinical blood chemistry	alanine transaminase (plasma ALT)	-15.069	5.2621	undefined	undefined	0.00770
clinical blood chemistry	albumin (plasma Alb)	-0.36951	0.38987	undefined	undefined	0.351
clinical blood chemistry	alkaline phosphatase (plasma ALP)	1.7349	3.6724	undefined	undefined	0.640
clinical blood chemistry	aspartate transaminase (plasma AST)	-8.5640	9.5034	undefined	undefined	0.375
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	0.13273	0.15040	undefined	undefined	0.385
clinical blood chemistry	blood urea nitrogen (BUN)	0.63361	1.4971	undefined	undefined	0.675
clinical blood chemistry	calcium (plasma Ca)	0.051842	0.053654	undefined	undefined	0.342
clinical blood chemistry	creatinine (plasma)	-0.030362	0.025208	undefined	undefined	0.238
clinical blood chemistry	glucose (plasma GLU, no fast)	14.455	10.980	undefined	undefined	0.199
clinical blood chemistry	HDL cholesterol (plasma HDL)	0.44035	2.3691	undefined	undefined	0.854
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	0.015571	0.0068906	undefined	undefined	0.0315
clinical blood chemistry	phosphorus (plasma phosphate)	-0.10193	0.36558	undefined	undefined	0.782
clinical blood chemistry	total bilirubin (plasma TBIL)	-0.011940	0.0060668	undefined	undefined	0.0590
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	-0.26066	3.2718	undefined	undefined	0.937
clinical blood chemistry	total protein (plasma TP)	-0.62628	0.54340	undefined	undefined	0.259
clinical blood chemistry	triglyceride (plasma TG, no fast)	-11.859	11.448	undefined	undefined	0.309
glucose tolerance test	amount glucose injected	-1.2970	2.9080	undefined	undefined	0.659
glucose tolerance test	plasma glucose, 0min	5.0599	9.1208	undefined	undefined	0.583
glucose tolerance test	plasma glucose, 15min	-1.2574	15.283	undefined	undefined	0.935
glucose tolerance test	plasma glucose, 30min	1.7884	11.877	undefined	undefined	0.881
glucose tolerance test	plasma glucose, 60min	-4.7766	9.1680	undefined	undefined	0.606
glucose tolerance test	plasma glucose, 120min	-1.1300	8.6302	undefined	undefined	0.897
grip strength	body weight (at time of grip strength test)	-1.8985	0.62642	undefined	undefined	0.00577
grip strength	forelimb and hindlimb grip strength (mean of trials), average	-7.5062	7.4191	undefined	undefined	0.322
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	-0.40986	0.35786	undefined	undefined	0.264
grip strength	forelimb and hindlimb grip strength by trial, trial1	-4.7919	8.9427	undefined	undefined	0.597
grip strength	forelimb and hindlimb grip strength by trial, trial2	-0.50590	8.0391	undefined	undefined	0.950
grip strength	forelimb and hindlimb grip strength by trial, trial3	-20.358	6.7984	undefined	undefined	0.00629
grip strength	forelimb grip strength (mean of trials), average	1.5199	4.3376	undefined	undefined	0.729
grip strength	forelimb grip strength (mean of trials), average normalized to bw	0.21921	0.26218	undefined	undefined	0.412
grip strength	forelimb grip strength by trial, trial1	0.88076	4.1716	undefined	undefined	0.835
grip strength	forelimb grip strength by trial, trial2	1.3607	4.5728	undefined	undefined	0.769
grip strength	forelimb grip strength by trial, trial3	6.2416	6.1304	undefined	undefined	0.319
heart weight	heart weight, normalized to body weight	0.14494	0.15880	undefined	undefined	0.369
heart weight	heart weight, weight	0.72374	3.6256	undefined	undefined	0.843
hematology	basophil differential (percent of total WBC)	-0.012403	0.038527	undefined	undefined	0.750
hematology	eosinophil differential (percent of total WBC)	-0.27716	0.24922	undefined	undefined	0.275
hematology	hematocrit (HCT)	0.083869	0.49966	undefined	undefined	0.868
hematology	lymphocyte differential (percent of total WBC)	1.3811	0.94510	undefined	undefined	0.155
hematology	mean corpuscular hemoglobin (CHr)	0.034741	0.055063	undefined	undefined	0.533
hematology	mean platelet volume (MPV)	-0.032607	0.034095	undefined	undefined	0.347
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	-0.068274	0.11379	undefined	undefined	0.553
hematology	mean RBC corpuscular volume (MCV)	0.15413	0.18999	undefined	undefined	0.424
hematology	measured hemoglobin (mHGB)	-0.047545	0.16655	undefined	undefined	0.777
hematology	monocyte differential (percent of total WBC)	-0.097927	0.21163	undefined	undefined	0.647
hematology	neutrophil differential (percent of total WBC)	-0.82898	0.58971	undefined	undefined	0.171
hematology	platelet count (PLT; units per volume x 10³)	37.581	34.899	undefined	undefined	0.290
hematology	RBC corpuscular distribution width (RDW)	0.20370	0.15421	undefined	undefined	0.197
hematology	red blood cell count (RBC; per volume x 10⁶)	0.017031	0.11114	undefined	undefined	0.879
hematology	reticulocyte count (Retic; units per volume x 10⁹)	-23.432	13.027	undefined	undefined	0.0825
hematology	reticulocyte differential (percent of total RBC)	-0.22995	0.12886	undefined	undefined	0.0848
hematology	white blood cell count (WBC; units per volume x 10³)	-0.053947	0.62235	undefined	undefined	0.932
holeboard	number of hole pokes by individual hole number, 20 min test, 1	1.1875	1.8528	undefined	undefined	0.526
holeboard	number of hole pokes by individual hole number, 20 min test, 2	0.068785	1.0146	undefined	undefined	0.946
holeboard	number of hole pokes by individual hole number, 20 min test, 3	0.16773	0.82265	undefined	undefined	0.840
holeboard	number of hole pokes by individual hole number, 20 min test, 4	0.61802	1.5169	undefined	undefined	0.687
holeboard	number of hole pokes by individual hole number, 20 min test, 5	-1.0323	0.76427	undefined	undefined	0.187
holeboard	number of hole pokes by individual hole number, 20 min test, 6	1.0292	0.40871	undefined	undefined	0.0176
holeboard	number of hole pokes by individual hole number, 20 min test, 7	0.048483	0.52559	undefined	undefined	0.927
holeboard	number of hole pokes by individual hole number, 20 min test, 8	-0.17179	0.85339	undefined	undefined	0.842
holeboard	number of hole pokes by individual hole number, 20 min test, 9	-0.26189	0.73311	undefined	undefined	0.723
holeboard	number of hole pokes by individual hole number, 20 min test, 10	0.17039	0.64322	undefined	undefined	0.793
holeboard	number of hole pokes by individual hole number, 20 min test, 11	0.95592	0.59550	undefined	undefined	0.119
holeboard	number of hole pokes by individual hole number, 20 min test, 12	0.95411	0.58892	undefined	undefined	0.116
holeboard	number of hole pokes by individual hole number, 20 min test, 13	0.39320	1.1871	undefined	undefined	0.743
holeboard	number of hole pokes by individual hole number, 20 min test, 14	-0.22975	1.0028	undefined	undefined	0.820
holeboard	number of hole pokes by individual hole number, 20 min test, 15	0.86027	0.68168	undefined	undefined	0.217
holeboard	number of hole pokes by individual hole number, 20 min test, 16	2.7197	0.95881	undefined	undefined	0.00809
holeboard	total number of hole pokes, 20 min test	6.5272	7.8807	undefined	undefined	0.414
light / dark	latency to enter dark zone, 20 min test	32.861	24.119	undefined	undefined	0.183
light / dark	number of transitions between light and dark zones, 20 min test	-3.8938	7.6153	undefined	undefined	0.613
light / dark	percentage of total time in dark zone, 20 min test	11.140	4.4429	undefined	undefined	0.0178
light / dark	percentage of total time in light zone, 20 min test	-11.140	4.4429	undefined	undefined	0.0178
light / dark	time mobile in dark zone, 20 min test	7.9531	3.6792	undefined	undefined	0.0388
light / dark	time mobile in light zone, 20 min test	-12.007	5.3247	undefined	undefined	0.0319
light / dark	time spent in dark zone, 20 min test	101.15	46.511	undefined	undefined	0.0377
light / dark	time spent in light zone, 20 min test	-101.15	46.511	undefined	undefined	0.0377
open field	average speed in center of arena, 20 min test	1.0186	0.61315	undefined	undefined	0.107
open field	average speed in periphery of arena, 20 min test	0.18958	0.30590	undefined	undefined	0.540
open field	distance traveled habituation ratio, 20 min test	14.222	10.166	undefined	undefined	0.172
open field	distance traveled in center of arena, 20 min test	15.920	142.89	undefined	undefined	0.912
open field	distance traveled in periphery of arena, 20 min test	337.86	310.85	undefined	undefined	0.286
open field	distance traveled slope, 20 min test	16.371	9.7428	undefined	undefined	0.103
open field	distance traveled, 20 min test, 1st 5min	71.458	107.17	undefined	undefined	0.510
open field	distance traveled, 20 min test, 2nd 5min	-14.224	110.22	undefined	undefined	0.898
open field	distance traveled, 20 min test, 3rd 5min	113.60	117.18	undefined	undefined	0.340
open field	distance traveled, 20 min test, 4th 5min	57.470	123.29	undefined	undefined	0.645
open field	number of clockwise revolution episodes, 20 min test	-0.029459	2.5704	undefined	undefined	0.991
open field	number of counter-clockwise revolution episodes, 20 min test	0.048741	2.3553	undefined	undefined	0.984
open field	number of rears in 5 min bins, 20 min test, 1st 5min	-3.0444	3.5527	undefined	undefined	0.398
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	-6.2955	4.1773	undefined	undefined	0.142
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	0.085475	4.9606	undefined	undefined	0.986
open field	number of rears in 5 min bins, 20 min test, 4th 5min	-1.9720	3.9715	undefined	undefined	0.623
open field	percentage of total time in center of arena, 20 min test	-4.8789	3.5836	undefined	undefined	0.184
open field	percentage of total time in center of arena, slope, 20 min test	-4.0731	1.3063	undefined	undefined	0.00400
open field	percentage of total time in center, habituation ratio, 20 min test	-4.0229	1.2482	undefined	undefined	0.00305
open field	percentage of total time in corners of arena, 20 min test	5.2525	3.2699	undefined	undefined	0.119
open field	percentage of total time in corners, habituation ratio, 20 min test	2.3282	1.6158	undefined	undefined	0.160
open field	percentage of total time in corners, slope, 20 min test	2.3418	1.6340	undefined	undefined	0.162
open field	permanence time in center of arena, 20 min test	-58.544	43.003	undefined	undefined	0.184
open field	permanence time in corners of arena, 20 min test	63.011	39.239	undefined	undefined	0.119
open field	permanence time in periphery of arena, 20 min test	58.542	43.003	undefined	undefined	0.184
open field	total distance traveled, 20 min test	346.14	412.64	undefined	undefined	0.408
open field	total number of rears, 20 min test	-3.8665	15.612	undefined	undefined	0.806
open field	whole arena average speed, 20 min test	0.28846	0.34398	undefined	undefined	0.408
open field	whole arena resting time, 20 min test	-23.461	23.161	undefined	undefined	0.319
open field	whole arena time spent mobile, 20 min test	3.6510	5.4364	undefined	undefined	0.507
open field	whole arena time spent vertical, 20 min test	1.2436	7.7308	undefined	undefined	0.873
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	1.2127	2.0300	undefined	undefined	0.556
startle / PPI	average baseline movement during background noise	-0.47096	1.3956	undefined	undefined	0.738
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	0.11624	0.10549	undefined	undefined	0.279
startle / PPI	average of each corrected percent pre-pulse inhibition value	0.093900	0.085437	undefined	undefined	0.280
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	27.604	11.197	undefined	undefined	0.0196
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.51706	7.7675	undefined	undefined	0.947
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-1.9837	6.6319	undefined	undefined	0.767
startle / PPI	average startle response to full pulse (120 dB)	12.456	52.900	undefined	undefined	0.815
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-36.947	50.743	undefined	undefined	0.472
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-6.7613	47.407	undefined	undefined	0.888
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-2.8480	44.793	undefined	undefined	0.950
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	2.4043	1.5142	undefined	undefined	0.123
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	2.8831	1.2765	undefined	undefined	0.0313
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	0.53276	4.2045	undefined	undefined	0.900
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.31392	0.12760	undefined	undefined	0.0199
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.010527	0.090111	undefined	undefined	0.908
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-0.042751	0.082178	undefined	undefined	0.607
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	13.360	52.748	undefined	undefined	0.802
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	-40.158	51.004	undefined	undefined	0.437
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	-8.7435	47.600	undefined	undefined	0.856
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	-28.084	40.313	undefined	undefined	0.491
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.36259	0.16127	undefined	undefined	0.0321
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.012282	0.10782	undefined	undefined	0.910
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-0.026150	0.088493	undefined	undefined	0.770
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	57.053	188.70	undefined	undefined	0.765
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	-134.01	190.34	undefined	undefined	0.487
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	-11.721	164.24	undefined	undefined	0.944
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	-2.5921	168.20	undefined	undefined	0.988
startle / PPI	maximum baseline movement during background noise	-0.96932	3.2370	undefined	undefined	0.767
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	33.014	14.222	undefined	undefined	0.0273
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.74477	9.4321	undefined	undefined	0.938
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-0.46640	7.9042	undefined	undefined	0.953
startle / PPI	maximum startle response to full pulse (120 dB)	56.074	189.01	undefined	undefined	0.769
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-127.43	189.44	undefined	undefined	0.507
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-8.8153	163.84	undefined	undefined	0.957
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	3.1540	164.72	undefined	undefined	0.985
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	5.0951	3.4866	undefined	undefined	0.154
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	2.9058	3.1644	undefined	undefined	0.366
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	-0.56430	8.8221	undefined	undefined	0.949

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

In this plot, data points are the computed genotype effect % vs. C57BL/6NJ controls, for all measured categorical phenotypes in JaxKOMP-EAP

Dimensions Width: × Height: px

Plot Options Group by Procedure

Include Sexes Data Both Females Males

Significance Threshold p-Value Threshold

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Procedure	JaxKOMP-EAP Trait	Sex	Trait Effect	P-value

eye morphology	anterior chamber depth	females	1.0 %	1.0
eye morphology	anterior chamber depth	males	0.0 %	1.0
eye morphology	anterior chamber depth	both	1.0 %	1.0
eye morphology	bulging eye	females	1.0 %	1.0
eye morphology	bulging eye	males	0.0 %	1.0
eye morphology	bulging eye	both	1.0 %	1.00
eye morphology	cornea	females	4.0 %	1.0
eye morphology	cornea	males	2.0 %	1.0
eye morphology	cornea	both	3.0 %	1.00
eye morphology	cornea opacity	females	5.0 %	1.00
eye morphology	cornea opacity	males	1.0 %	1.0
eye morphology	cornea opacity	both	3.0 %	1.00
eye morphology	cornea vascularization	females	3.0 %	1.0
eye morphology	cornea vascularization	males	1.0 %	1.0
eye morphology	cornea vascularization	both	2.0 %	1.00
eye morphology	corneal deposits	females	2.0 %	1.0
eye morphology	corneal deposits	males	1.0 %	1.0
eye morphology	corneal deposits	both	1.0 %	1.00
eye morphology	corneal mineralization	females	2.0 %	1.0
eye morphology	corneal mineralization	males	1.0 %	1.0
eye morphology	corneal mineralization	both	1.0 %	1.00
eye morphology	corneal scleralization	females	3.0 %	1.00
eye morphology	corneal scleralization	males	1.0 %	1.0
eye morphology	corneal scleralization	both	2.0 %	1.00
eye morphology	corneal ulcer	females	1.0 %	1.0
eye morphology	corneal ulcer	males	1.0 %	1.0
eye morphology	corneal ulcer	both	1.0 %	1.00
eye morphology	eye closure	females	1.0 %	1.00
eye morphology	eye closure	males	0.0 %	1.0
eye morphology	eye closure	both	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	females	2.0 %	1.00
eye morphology	eye hemorrhage or blood presence	males	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	both	1.0 %	1.00
eye morphology	eyelid morphology	females	1.0 %	1.0
eye morphology	eyelid morphology	males	0.0 %	1.0
eye morphology	eyelid morphology	both	1.0 %	1.0
eye morphology	eyes (present, absent)	females	1.0 %	1.0
eye morphology	eyes (present, absent)	males	0.0 %	1.0
eye morphology	eyes (present, absent)	both	0.0 %	1.0
eye morphology	fusion between cornea and lens	females	4.0 %	1.00
eye morphology	fusion between cornea and lens	males	2.0 %	1.0
eye morphology	fusion between cornea and lens	both	3.0 %	1.00
eye morphology	iris pigmentation	females	2.0 %	1.0
eye morphology	iris pigmentation	males	1.0 %	1.0
eye morphology	iris pigmentation	both	2.0 %	1.00
eye morphology	iris transillumination	females	2.0 %	1.00
eye morphology	iris transillumination	males	1.0 %	1.0
eye morphology	iris transillumination	both	1.0 %	1.00
eye morphology	irispupil	females	4.0 %	1.00
eye morphology	irispupil	males	3.0 %	1.0
eye morphology	irispupil	both	3.0 %	1.00
eye morphology	lacrimation	females	3.0 %	1.0
eye morphology	lacrimation	males	2.0 %	1.0
eye morphology	lacrimation	both	3.0 %	1.0
eye morphology	lens	females	10.0 %	1.00
eye morphology	lens	males	8.0 %	1.0
eye morphology	lens	both	9.0 %	1.0
eye morphology	lens opacity	females	9.0 %	0.531
eye morphology	lens opacity	males	6.0 %	1.0
eye morphology	lens opacity	both	3.0 %	0.703
eye morphology	narrow eye opening	females	2.0 %	1.0
eye morphology	narrow eye opening	males	1.0 %	1.0
eye morphology	narrow eye opening	both	1.0 %	1.0
eye morphology	optic disc	females	4.0 %	1.00
eye morphology	optic disc	males	2.0 %	1.0
eye morphology	optic disc	both	3.0 %	1.00
eye morphology	persistence of hyaloid vascular system	females	6.0 %	0.690
eye morphology	persistence of hyaloid vascular system	males	5.0 %	1.0
eye morphology	persistence of hyaloid vascular system	both	3.0 %	0.790
eye morphology	pupil dilation	females	2.0 %	1.0
eye morphology	pupil dilation	males	1.0 %	1.0
eye morphology	pupil dilation	both	2.0 %	1.0
eye morphology	pupil light response	females	2.0 %	1.00
eye morphology	pupil light response	males	1.0 %	1.0
eye morphology	pupil light response	both	2.0 %	1.00
eye morphology	pupil position	females	4.0 %	1.00
eye morphology	pupil position	males	3.0 %	1.0
eye morphology	pupil position	both	4.0 %	1.00
eye morphology	pupil shape	females	3.0 %	1.00
eye morphology	pupil shape	males	2.0 %	1.0
eye morphology	pupil shape	both	3.0 %	1.00
eye morphology	retina	females	10.0 %	0.560
eye morphology	retina	males	16.0 %	1.0
eye morphology	retina	both	7.0 %	0.888
eye morphology	retinal blood vessels	females	4.0 %	1.0
eye morphology	retinal blood vessels	males	2.0 %	1.0
eye morphology	retinal blood vessels	both	3.0 %	1.0
eye morphology	retinal blood vessels pattern	females	25.0 %	0.00657
eye morphology	retinal blood vessels pattern	males	12.0 %	0.0675
eye morphology	retinal blood vessels pattern	both	15.0 %	0.00110
eye morphology	retinal blood vessels structure	females	4.0 %	1.00
eye morphology	retinal blood vessels structure	males	12.0 %	0.0476
eye morphology	retinal blood vessels structure	both	6.0 %	0.0640
eye morphology	retinal pigmentation	females	12.0 %	1.0
eye morphology	retinal pigmentation	males	14.0 %	1.0
eye morphology	retinal pigmentation	both	13.0 %	1.0
eye morphology	retinal structure	females	4.0 %	1.00
eye morphology	retinal structure	males	2.0 %	1.0
eye morphology	retinal structure	both	3.0 %	1.00
eye morphology	synechia	females	4.0 %	1.0
eye morphology	synechia	males	2.0 %	1.0
eye morphology	synechia	both	3.0 %	1.00
eye morphology	vitreous	females	4.0 %	1.00
eye morphology	vitreous	males	2.0 %	1.0
eye morphology	vitreous	both	3.0 %	1.00
SHIRPA	activity body position	females	1.0 %	1.0
SHIRPA	activity body position	males	14.0 %	0.0549
SHIRPA	activity body position	both	7.0 %	0.0842
SHIRPA	aggression	females	0.0 %	1.0
SHIRPA	aggression	males	1.0 %	1.0
SHIRPA	aggression	both	1.0 %	1.0
SHIRPA	body length	females	0.0 %	1.0
SHIRPA	body length	males	0.0 %	1.0
SHIRPA	body length	both	0.0 %	1.0
SHIRPA	body position	females	0.0 %	1.0
SHIRPA	body position	males	1.0 %	1.0
SHIRPA	body position	both	0.0 %	1.0
SHIRPA	body thickness	females	1.0 %	1.0
SHIRPA	body thickness	males	0.0 %	1.0
SHIRPA	body thickness	both	0.0 %	1.0
SHIRPA	coat color abdomen	females	3.0 %	1.0
SHIRPA	coat color abdomen	males	4.0 %	1.00
SHIRPA	coat color abdomen	both	4.0 %	1.00
SHIRPA	coat color back	females	0.0 %	1.0
SHIRPA	coat color back	males	0.0 %	1.0
SHIRPA	coat color back	both	0.0 %	1.00
SHIRPA	coat color head	females	0.0 %	1.0
SHIRPA	coat color head	males	0.0 %	1.0
SHIRPA	coat color head	both	0.0 %	1.0
SHIRPA	coat color pattern abdomen	females	1.0 %	1.0
SHIRPA	coat color pattern abdomen	males	1.0 %	1.0
SHIRPA	coat color pattern abdomen	both	1.0 %	1.0
SHIRPA	coat color pattern back	females	0.0 %	1.0
SHIRPA	coat color pattern back	males	0.0 %	1.0
SHIRPA	coat color pattern back	both	0.0 %	1.00
SHIRPA	coat color pattern head	females	0.0 %	1.0
SHIRPA	coat color pattern head	males	0.0 %	1.00
SHIRPA	coat color pattern head	both	0.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	females	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	males	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	both	2.0 %	1.0
SHIRPA	coat hair back texture appearance	females	0.0 %	1.0
SHIRPA	coat hair back texture appearance	males	0.0 %	1.0
SHIRPA	coat hair back texture appearance	both	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	females	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	males	1.0 %	1.0
SHIRPA	coat hair distribution abdomen	both	1.0 %	1.00
SHIRPA	coat hair distribution back	females	0.0 %	1.0
SHIRPA	coat hair distribution back	males	0.0 %	1.0
SHIRPA	coat hair distribution back	both	0.0 %	1.0
SHIRPA	coat hair distribution head	females	1.0 %	1.0
SHIRPA	coat hair distribution head	males	1.0 %	1.0
SHIRPA	coat hair distribution head	both	1.0 %	1.0
SHIRPA	coat hair head texture appearance	females	0.0 %	1.00
SHIRPA	coat hair head texture appearance	males	0.0 %	1.0
SHIRPA	coat hair head texture appearance	both	0.0 %	1.0
SHIRPA	contact righting	females	5.0 %	1.0
SHIRPA	contact righting	males	5.0 %	1.00
SHIRPA	contact righting	both	5.0 %	1.0
SHIRPA	ear morphology	females	0.0 %	1.0
SHIRPA	ear morphology	males	0.0 %	1.0
SHIRPA	ear morphology	both	0.0 %	1.0
SHIRPA	fat distribution	females	0.0 %	1.0
SHIRPA	fat distribution	males	0.0 %	1.0
SHIRPA	fat distribution	both	0.0 %	1.0
SHIRPA	forelimb digit number	females	0.0 %	1.00
SHIRPA	forelimb digit number	males	0.0 %	1.0
SHIRPA	forelimb digit number	both	0.0 %	1.0
SHIRPA	forelimb digit position	females	0.0 %	1.0
SHIRPA	forelimb digit position	males	0.0 %	1.0
SHIRPA	forelimb digit position	both	0.0 %	1.0
SHIRPA	forelimb digit shape	females	0.0 %	1.0
SHIRPA	forelimb digit shape	males	0.0 %	1.0
SHIRPA	forelimb digit shape	both	0.0 %	1.0
SHIRPA	forelimb digit size	females	0.0 %	1.0
SHIRPA	forelimb digit size	males	0.0 %	1.0
SHIRPA	forelimb digit size	both	0.0 %	1.0
SHIRPA	forelimb footpads	females	0.0 %	1.0
SHIRPA	forelimb footpads	males	0.0 %	1.0
SHIRPA	forelimb footpads	both	0.0 %	1.0
SHIRPA	forelimb nail length	females	0.0 %	1.0
SHIRPA	forelimb nail length	males	0.0 %	1.0
SHIRPA	forelimb nail length	both	0.0 %	1.0
SHIRPA	forelimb nail number	females	0.0 %	1.0
SHIRPA	forelimb nail number	males	0.0 %	1.0
SHIRPA	forelimb nail number	both	0.0 %	1.0
SHIRPA	forelimb nail position	females	0.0 %	1.0
SHIRPA	forelimb nail position	males	0.0 %	1.0
SHIRPA	forelimb nail position	both	0.0 %	1.0
SHIRPA	forelimb nail shape	females	0.0 %	1.0
SHIRPA	forelimb nail shape	males	0.0 %	1.0
SHIRPA	forelimb nail shape	both	0.0 %	1.0
SHIRPA	forelimbs position	females	0.0 %	1.0
SHIRPA	forelimbs position	males	0.0 %	1.0
SHIRPA	forelimbs position	both	0.0 %	1.0
SHIRPA	forelimbs shape	females	0.0 %	1.0
SHIRPA	forelimbs shape	males	0.0 %	1.0
SHIRPA	forelimbs shape	both	0.0 %	1.0
SHIRPA	forelimbs size	females	0.0 %	1.0
SHIRPA	forelimbs size	males	0.0 %	1.00
SHIRPA	forelimbs size	both	0.0 %	1.00
SHIRPA	forepaw position	females	0.0 %	1.0
SHIRPA	forepaw position	males	0.0 %	1.0
SHIRPA	forepaw position	both	0.0 %	1.0
SHIRPA	forepaw shape	females	0.0 %	1.0
SHIRPA	forepaw shape	males	0.0 %	1.0
SHIRPA	forepaw shape	both	0.0 %	1.0
SHIRPA	forepaw size	females	0.0 %	1.0
SHIRPA	forepaw size	males	0.0 %	1.0
SHIRPA	forepaw size	both	0.0 %	1.0
SHIRPA	gait (fluidity)	females	0.0 %	1.0
SHIRPA	gait (fluidity)	males	0.0 %	1.0
SHIRPA	gait (fluidity)	both	0.0 %	1.0
SHIRPA	genitalia morphology	females	0.0 %	1.00
SHIRPA	genitalia morphology	males	0.0 %	1.0
SHIRPA	genitalia morphology	both	0.0 %	1.0
SHIRPA	genitalia presence	females	0.0 %	1.0
SHIRPA	genitalia presence	males	0.0 %	1.0
SHIRPA	genitalia presence	both	0.0 %	1.0
SHIRPA	genitalia size	females	0.0 %	1.0
SHIRPA	genitalia size	males	0.0 %	1.00
SHIRPA	genitalia size	both	0.0 %	1.0
SHIRPA	head bobbing	females	0.0 %	1.0
SHIRPA	head bobbing	males	0.0 %	1.0
SHIRPA	head bobbing	both	0.0 %	1.0
SHIRPA	head morphology	females	0.0 %	1.0
SHIRPA	head morphology	males	0.0 %	1.0
SHIRPA	head morphology	both	0.0 %	1.00
SHIRPA	head size	females	0.0 %	1.0
SHIRPA	head size	males	0.0 %	1.00
SHIRPA	head size	both	0.0 %	1.0
SHIRPA	hindlimb digit number	females	1.0 %	1.00
SHIRPA	hindlimb digit number	males	0.0 %	1.0
SHIRPA	hindlimb digit number	both	0.0 %	1.0
SHIRPA	hindlimb digit position	females	0.0 %	1.0
SHIRPA	hindlimb digit position	males	0.0 %	1.0
SHIRPA	hindlimb digit position	both	0.0 %	1.0
SHIRPA	hindlimb digit shape	females	0.0 %	1.0
SHIRPA	hindlimb digit shape	males	0.0 %	1.0
SHIRPA	hindlimb digit shape	both	0.0 %	1.0
SHIRPA	hindlimb digit size	females	0.0 %	1.00
SHIRPA	hindlimb digit size	males	0.0 %	1.00
SHIRPA	hindlimb digit size	both	0.0 %	1.0
SHIRPA	hindlimb nail length	females	0.0 %	1.0
SHIRPA	hindlimb nail length	males	0.0 %	1.00
SHIRPA	hindlimb nail length	both	0.0 %	1.0
SHIRPA	hindlimb nail number	females	0.0 %	1.0
SHIRPA	hindlimb nail number	males	1.0 %	1.00
SHIRPA	hindlimb nail number	both	0.0 %	1.0
SHIRPA	hindlimb nail position	females	0.0 %	1.0
SHIRPA	hindlimb nail position	males	0.0 %	1.0
SHIRPA	hindlimb nail position	both	0.0 %	1.0
SHIRPA	hindlimb nail shape	females	0.0 %	1.0
SHIRPA	hindlimb nail shape	males	0.0 %	1.0
SHIRPA	hindlimb nail shape	both	0.0 %	1.0
SHIRPA	hindlimbs footpads	females	0.0 %	1.0
SHIRPA	hindlimbs footpads	males	0.0 %	1.0
SHIRPA	hindlimbs footpads	both	0.0 %	1.0
SHIRPA	hindlimbs position	females	0.0 %	1.0
SHIRPA	hindlimbs position	males	0.0 %	1.0
SHIRPA	hindlimbs position	both	0.0 %	1.0
SHIRPA	hindlimbs shape	females	0.0 %	1.0
SHIRPA	hindlimbs shape	males	0.0 %	1.0
SHIRPA	hindlimbs shape	both	0.0 %	1.0
SHIRPA	hindlimbs size	females	0.0 %	1.0
SHIRPA	hindlimbs size	males	0.0 %	1.0
SHIRPA	hindlimbs size	both	0.0 %	1.0
SHIRPA	hindpaw position	females	0.0 %	1.0
SHIRPA	hindpaw position	males	0.0 %	1.0
SHIRPA	hindpaw position	both	0.0 %	1.0
SHIRPA	hindpaw shape	females	0.0 %	1.0
SHIRPA	hindpaw shape	males	0.0 %	1.0
SHIRPA	hindpaw shape	both	0.0 %	1.0
SHIRPA	hindpaw size	females	0.0 %	1.0
SHIRPA	hindpaw size	males	0.0 %	1.0
SHIRPA	hindpaw size	both	0.0 %	1.0
SHIRPA	limb grasp	females	9.0 %	1.0
SHIRPA	limb grasp	males	6.0 %	1.0
SHIRPA	limb grasp	both	7.0 %	0.618
SHIRPA	lower lip morphology	females	0.0 %	1.0
SHIRPA	lower lip morphology	males	0.0 %	1.0
SHIRPA	lower lip morphology	both	0.0 %	1.0
SHIRPA	lower teeth appearance	females	0.0 %	1.0
SHIRPA	lower teeth appearance	males	0.0 %	1.0
SHIRPA	lower teeth appearance	both	0.0 %	1.0
SHIRPA	mouth morphology	females	0.0 %	1.0
SHIRPA	mouth morphology	males	0.0 %	1.0
SHIRPA	mouth morphology	both	0.0 %	1.0
SHIRPA	salivation	females	0.0 %	1.0
SHIRPA	salivation	males	0.0 %	1.0
SHIRPA	salivation	both	0.0 %	1.0
SHIRPA	skin color back paws	females	0.0 %	1.0
SHIRPA	skin color back paws	males	0.0 %	1.0
SHIRPA	skin color back paws	both	0.0 %	1.0
SHIRPA	skin color ear	females	0.0 %	1.0
SHIRPA	skin color ear	males	0.0 %	1.0
SHIRPA	skin color ear	both	0.0 %	1.0
SHIRPA	skin color front paws	females	0.0 %	1.0
SHIRPA	skin color front paws	males	0.0 %	1.0
SHIRPA	skin color front paws	both	0.0 %	1.0
SHIRPA	skin color snout	females	0.0 %	1.0
SHIRPA	skin color snout	males	0.0 %	1.0
SHIRPA	skin color snout	both	0.0 %	1.0
SHIRPA	skin color tail	females	0.0 %	1.0
SHIRPA	skin color tail	males	0.0 %	1.0
SHIRPA	skin color tail	both	0.0 %	1.0
SHIRPA	skin color whole body	females	0.0 %	1.0
SHIRPA	skin color whole body	males	0.0 %	1.0
SHIRPA	skin color whole body	both	0.0 %	1.0
SHIRPA	skin texture back paw	females	0.0 %	1.0
SHIRPA	skin texture back paw	males	0.0 %	1.0
SHIRPA	skin texture back paw	both	0.0 %	1.0
SHIRPA	skin texture ear	females	0.0 %	1.0
SHIRPA	skin texture ear	males	0.0 %	1.0
SHIRPA	skin texture ear	both	0.0 %	1.0
SHIRPA	skin texture front paws	females	0.0 %	1.0
SHIRPA	skin texture front paws	males	0.0 %	1.0
SHIRPA	skin texture front paws	both	0.0 %	1.0
SHIRPA	skin texture snout	females	0.0 %	1.0
SHIRPA	skin texture snout	males	0.0 %	1.0
SHIRPA	skin texture snout	both	0.0 %	1.0
SHIRPA	skin texture tail	females	0.0 %	1.0
SHIRPA	skin texture tail	males	0.0 %	1.0
SHIRPA	skin texture tail	both	0.0 %	1.0
SHIRPA	skin texture whole body	females	0.0 %	1.0
SHIRPA	skin texture whole body	males	0.0 %	1.0
SHIRPA	skin texture whole body	both	0.0 %	1.00
SHIRPA	snout size	females	0.0 %	1.0
SHIRPA	snout size	males	1.0 %	1.0
SHIRPA	snout size	both	0.0 %	1.0
SHIRPA	startle response	females	0.0 %	1.0
SHIRPA	startle response	males	0.0 %	1.00
SHIRPA	startle response	both	0.0 %	1.00
SHIRPA	tail curvature	females	0.0 %	1.00
SHIRPA	tail curvature	males	0.0 %	1.0
SHIRPA	tail curvature	both	0.0 %	1.00
SHIRPA	tail elevation	females	1.0 %	1.00
SHIRPA	tail elevation	males	2.0 %	1.0
SHIRPA	tail elevation	both	1.0 %	1.0
SHIRPA	tail length	females	0.0 %	1.0
SHIRPA	tail length	males	0.0 %	1.00
SHIRPA	tail length	both	0.0 %	1.0
SHIRPA	tail morphology	females	0.0 %	1.0
SHIRPA	tail morphology	males	0.0 %	1.00
SHIRPA	tail morphology	both	0.0 %	1.00
SHIRPA	tail presence	females	0.0 %	1.0
SHIRPA	tail presence	males	0.0 %	1.0
SHIRPA	tail presence	both	0.0 %	1.0
SHIRPA	tail shape	females	0.0 %	1.0
SHIRPA	tail shape	males	0.0 %	1.0
SHIRPA	tail shape	both	0.0 %	1.0
SHIRPA	tail thickness	females	0.0 %	1.0
SHIRPA	tail thickness	males	0.0 %	1.0
SHIRPA	tail thickness	both	0.0 %	1.0
SHIRPA	teeth presence	females	0.0 %	1.0
SHIRPA	teeth presence	males	0.0 %	1.0
SHIRPA	teeth presence	both	0.0 %	1.0
SHIRPA	transfer arousal	females	1.0 %	1.0
SHIRPA	transfer arousal	males	14.0 %	0.0571
SHIRPA	transfer arousal	both	7.0 %	0.0887
SHIRPA	tremor	females	0.0 %	1.0
SHIRPA	tremor	males	0.0 %	1.0
SHIRPA	tremor	both	0.0 %	1.00
SHIRPA	trunk curl	females	0.0 %	1.0
SHIRPA	trunk curl	males	0.0 %	1.0
SHIRPA	trunk curl	both	0.0 %	1.00
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	females	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	males	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	both	0.0 %	1.0
SHIRPA	upper lip morphology	females	0.0 %	1.0
SHIRPA	upper lip morphology	males	0.0 %	1.0
SHIRPA	upper lip morphology	both	0.0 %	1.0
SHIRPA	upper teeth appearance	females	0.0 %	1.0
SHIRPA	upper teeth appearance	males	0.0 %	1.00
SHIRPA	upper teeth appearance	both	0.0 %	1.0
SHIRPA	vibrissae appearance	females	2.0 %	1.0
SHIRPA	vibrissae appearance	males	1.0 %	1.0
SHIRPA	vibrissae appearance	both	1.0 %	1.0
SHIRPA	vibrissae presence	females	2.0 %	1.00
SHIRPA	vibrissae presence	males	1.0 %	1.0
SHIRPA	vibrissae presence	both	2.0 %	1.0
SHIRPA	vocalization	females	2.0 %	1.00
SHIRPA	vocalization	males	2.0 %	1.0
SHIRPA	vocalization	both	2.0 %	1.0

GENOTYPE CORRELATION PLOT

Correlate Dmwd^em1(IMPC)J/Mmjax -/- with genotype: