MPD: JaxKOMP-EAP genotype: Fbxo3<sup>em1(IMPC)J</sup>/Mmjax -/+

JaxKOMP-EAP effect sizes: Fbxo3^em1(IMPC)J/Mmjax -/+ Gene Fbxo3

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value
clinical blood chemistry	alanine transaminase (plasma ALT)	6.1625	5.0970	undefined	undefined	0.239
clinical blood chemistry	albumin (plasma Alb)	0.58547	0.37980	undefined	undefined	0.138
clinical blood chemistry	alkaline phosphatase (plasma ALP)	0.35000	2.9007	undefined	undefined	0.905
clinical blood chemistry	aspartate transaminase (plasma AST)	16.578	8.3490	undefined	undefined	0.0603
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	0.064450	0.13698	undefined	undefined	0.643
clinical blood chemistry	blood urea nitrogen (BUN)	3.075	1.5421	undefined	undefined	0.0587
clinical blood chemistry	calcium (plasma Ca)	-0.087500	0.095547	undefined	undefined	0.370
clinical blood chemistry	creatinine (plasma)	0.018125	0.044795	undefined	undefined	0.690
clinical blood chemistry	glucose (plasma GLU, no fast)	-11.65	12.267	undefined	undefined	0.353
clinical blood chemistry	HDL cholesterol (plasma HDL)	-4.3725	3.0225	undefined	undefined	0.162
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	0.0032850	0.0096655	undefined	undefined	0.737
clinical blood chemistry	phosphorus (plasma phosphate)	0.34	0.39754	undefined	undefined	0.402
clinical blood chemistry	total bilirubin (plasma TBIL)	0.018125	0.0065492	undefined	undefined	0.0112
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	-6.75	4.5425	undefined	undefined	0.151
clinical blood chemistry	total protein (plasma TP)	0.30426	0.49268	undefined	undefined	0.544
clinical blood chemistry	triglyceride (plasma TG, no fast)	-5.5851	14.880	undefined	undefined	0.711
glucose tolerance test	amount glucose injected	0.65190	3.4408	undefined	undefined	0.852
glucose tolerance test	plasma glucose, 0min	6.1027	7.2007	undefined	undefined	0.406
glucose tolerance test	plasma glucose, 15min	14.651	12.129	undefined	undefined	0.241
glucose tolerance test	plasma glucose, 30min	43.080	25.565	undefined	undefined	0.107
glucose tolerance test	plasma glucose, 60min	12.000	12.360	undefined	undefined	0.343
glucose tolerance test	plasma glucose, 120min	4.9509	7.4076	undefined	undefined	0.511
grip strength	body weight (at time of grip strength test)	-1.1925	0.78518	undefined	undefined	0.160
grip strength	forelimb and hindlimb grip strength (mean of trials), average	-0.73438	4.7861	undefined	undefined	0.881
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	0.29280	0.25785	undefined	undefined	0.285
grip strength	forelimb and hindlimb grip strength by trial, trial1	3.8125	6.6167	undefined	undefined	0.577
grip strength	forelimb and hindlimb grip strength by trial, trial2	-7.7813	8.5870	undefined	undefined	0.386
grip strength	forelimb and hindlimb grip strength by trial, trial3	1.7656	6.0920	undefined	undefined	0.778
grip strength	forelimb grip strength (mean of trials), average	-4.3906	5.5872	undefined	undefined	0.450
grip strength	forelimb grip strength (mean of trials), average normalized to bw	0.091922	0.28279	undefined	undefined	0.752
grip strength	forelimb grip strength by trial, trial1	-4.7031	6.7326	undefined	undefined	0.501
grip strength	forelimb grip strength by trial, trial2	-6.6094	6.0182	undefined	undefined	0.298
grip strength	forelimb grip strength by trial, trial3	-1.8594	6.5969	undefined	undefined	0.784
heart weight	heart weight, normalized to body weight	-0.034741	0.17807	undefined	undefined	0.847
heart weight	heart weight, weight	-9.63	3.4969	undefined	undefined	0.0116
hematology	basophil differential (percent of total WBC)	-0.01125	0.034812	undefined	undefined	0.750
hematology	eosinophil differential (percent of total WBC)	0.17064	0.36182	undefined	undefined	0.642
hematology	hematocrit (HCT)	0.71250	0.57928	undefined	undefined	0.232
hematology	lymphocyte differential (percent of total WBC)	-1.6938	1.8628	undefined	undefined	0.373
hematology	mean corpuscular hemoglobin (CHr)	-0.057500	0.070451	undefined	undefined	0.423
hematology	mean platelet volume (MPV)	-0.043750	0.045831	undefined	undefined	0.350
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	-0.26250	0.14766	undefined	undefined	0.0893
hematology	mean RBC corpuscular volume (MCV)	0.21125	0.23863	undefined	undefined	0.386
hematology	measured hemoglobin (mHGB)	0.10500	0.17333	undefined	undefined	0.551
hematology	monocyte differential (percent of total WBC)	0.035000	0.43044	undefined	undefined	0.936
hematology	neutrophil differential (percent of total WBC)	1.2188	1.3833	undefined	undefined	0.388
hematology	platelet count (PLT; units per volume x 10³)	-61.950	55.854	undefined	undefined	0.279
hematology	RBC corpuscular distribution width (RDW)	0.26625	0.12986	undefined	undefined	0.0524
hematology	red blood cell count (RBC; per volume x 10⁶)	0.021965	0.13901	undefined	undefined	0.876
hematology	reticulocyte count (Retic; units per volume x 10⁹)	-6.0500	12.050	undefined	undefined	0.621
hematology	reticulocyte differential (percent of total RBC)	-0.012369	0.11509	undefined	undefined	0.915
hematology	white blood cell count (WBC; units per volume x 10³)	0.78975	0.84288	undefined	undefined	0.359
holeboard	number of hole pokes by individual hole number, 20 min test, 1	1.8704	1.1696	undefined	undefined	0.125
holeboard	number of hole pokes by individual hole number, 20 min test, 2	0.85	0.57749	undefined	undefined	0.155
holeboard	number of hole pokes by individual hole number, 20 min test, 3	0.2375	0.97621	undefined	undefined	0.810
holeboard	number of hole pokes by individual hole number, 20 min test, 4	0.91250	1.6077	undefined	undefined	0.576
holeboard	number of hole pokes by individual hole number, 20 min test, 5	0.5	0.85147	undefined	undefined	0.563
holeboard	number of hole pokes by individual hole number, 20 min test, 6	0.063395	0.49147	undefined	undefined	0.899
holeboard	number of hole pokes by individual hole number, 20 min test, 7	0.375	0.81463	undefined	undefined	0.650
holeboard	number of hole pokes by individual hole number, 20 min test, 8	1.125	1.3962	undefined	undefined	0.429
holeboard	number of hole pokes by individual hole number, 20 min test, 9	0.025000	0.59159	undefined	undefined	0.967
holeboard	number of hole pokes by individual hole number, 20 min test, 10	0.0125	0.48341	undefined	undefined	0.980
holeboard	number of hole pokes by individual hole number, 20 min test, 11	-0.35	0.48241	undefined	undefined	0.476
holeboard	number of hole pokes by individual hole number, 20 min test, 12	0.3	0.68873	undefined	undefined	0.667
holeboard	number of hole pokes by individual hole number, 20 min test, 13	0.7875	1.3446	undefined	undefined	0.564
holeboard	number of hole pokes by individual hole number, 20 min test, 14	-0.15	0.69243	undefined	undefined	0.830
holeboard	number of hole pokes by individual hole number, 20 min test, 15	-0.1125	0.83242	undefined	undefined	0.894
holeboard	number of hole pokes by individual hole number, 20 min test, 16	0.13750	1.2964	undefined	undefined	0.916
holeboard	total number of hole pokes, 20 min test	4.9375	9.0518	undefined	undefined	0.591
light / dark	latency to enter dark zone, 20 min test	54.079	64.142	undefined	undefined	0.408
light / dark	number of transitions between light and dark zones, 20 min test	0.61250	6.9901	undefined	undefined	0.931
light / dark	percentage of total time in dark zone, 20 min test	-4.4465	5.4692	undefined	undefined	0.425
light / dark	percentage of total time in light zone, 20 min test	4.4465	5.4692	undefined	undefined	0.425
light / dark	time mobile in dark zone, 20 min test	-4.0858	5.7264	undefined	undefined	0.483
light / dark	time mobile in light zone, 20 min test	3.6874	4.7985	undefined	undefined	0.450
light / dark	time spent in dark zone, 20 min test	-87.726	65.611	undefined	undefined	0.195
light / dark	time spent in light zone, 20 min test	87.726	65.611	undefined	undefined	0.195
open field	average speed in center of arena, 20 min test	0.36238	0.31240	undefined	undefined	0.258
open field	average speed in periphery of arena, 20 min test	0.18212	0.18248	undefined	undefined	0.329
open field	distance traveled habituation ratio, 20 min test	12.066	9.8217	undefined	undefined	0.232
open field	distance traveled in center of arena, 20 min test	95.606	120.70	undefined	undefined	0.437
open field	distance traveled in periphery of arena, 20 min test	172.51	168.03	undefined	undefined	0.316
open field	distance traveled slope, 20 min test	11.899	9.8788	undefined	undefined	0.241
open field	distance traveled, 20 min test, 1st 5min	-22.373	85.118	undefined	undefined	0.795
open field	distance traveled, 20 min test, 2nd 5min	86.534	69.937	undefined	undefined	0.229
open field	distance traveled, 20 min test, 3rd 5min	117.73	83.182	undefined	undefined	0.171
open field	distance traveled, 20 min test, 4th 5min	86.219	74.534	undefined	undefined	0.260
open field	number of clockwise revolution episodes, 20 min test	-0.67080	1.6978	undefined	undefined	0.697
open field	number of counter-clockwise revolution episodes, 20 min test	-0.037500	2.0382	undefined	undefined	0.985
open field	number of rears in 5 min bins, 20 min test, 1st 5min	-2.275	3.4692	undefined	undefined	0.519
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	-6.3750	4.5350	undefined	undefined	0.174
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	-9.6500	4.0043	undefined	undefined	0.0248
open field	number of rears in 5 min bins, 20 min test, 4th 5min	-1.9067	5.3231	undefined	undefined	0.724
open field	percentage of total time in center of arena, 20 min test	-0.73288	3.6240	undefined	undefined	0.842
open field	percentage of total time in center of arena, slope, 20 min test	1.8905	2.2336	undefined	undefined	0.406
open field	percentage of total time in center, habituation ratio, 20 min test	1.3612	2.3889	undefined	undefined	0.575
open field	percentage of total time in corners of arena, 20 min test	-0.33475	2.9141	undefined	undefined	0.910
open field	percentage of total time in corners, habituation ratio, 20 min test	-2.6151	2.4989	undefined	undefined	0.307
open field	percentage of total time in corners, slope, 20 min test	-1.0731	1.8514	undefined	undefined	0.568
open field	permanence time in center of arena, 20 min test	-8.8072	43.484	undefined	undefined	0.841
open field	permanence time in corners of arena, 20 min test	-4.0099	34.965	undefined	undefined	0.910
open field	permanence time in periphery of arena, 20 min test	8.8035	43.485	undefined	undefined	0.841
open field	total distance traveled, 20 min test	268.11	242.93	undefined	undefined	0.282
open field	total number of rears, 20 min test	-25.8	13.417	undefined	undefined	0.0675
open field	whole arena average speed, 20 min test	0.22238	0.20211	undefined	undefined	0.283
open field	whole arena resting time, 20 min test	27.157	31.548	undefined	undefined	0.399
open field	whole arena time spent mobile, 20 min test	4.5359	4.9717	undefined	undefined	0.371
open field	whole arena time spent vertical, 20 min test	-14.191	7.4882	undefined	undefined	0.0713
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	-0.17188	2.4179	undefined	undefined	0.945
startle / PPI	average baseline movement during background noise	-2.4354	1.8466	undefined	undefined	0.201
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	0.027403	0.087237	undefined	undefined	0.756
startle / PPI	average of each corrected percent pre-pulse inhibition value	0.038667	0.084864	undefined	undefined	0.653
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-1.0050	11.724	undefined	undefined	0.932
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	6.7521	9.4978	undefined	undefined	0.485
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-0.38713	8.6818	undefined	undefined	0.965
startle / PPI	average startle response to full pulse (120 dB)	5.2083	63.443	undefined	undefined	0.935
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	7.2271	71.806	undefined	undefined	0.921
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-14.490	65.833	undefined	undefined	0.828
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	3.8833	58.824	undefined	undefined	0.948
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	0.28542	2.1459	undefined	undefined	0.895
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	-0.17917	1.8017	undefined	undefined	0.922
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	0.22500	4.0408	undefined	undefined	0.956
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.00053173	0.11346	undefined	undefined	0.996
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.093199	0.10033	undefined	undefined	0.363
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.022270	0.094772	undefined	undefined	0.816
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	7.6437	64.057	undefined	undefined	0.906
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	6.9417	71.265	undefined	undefined	0.923
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	-14.310	66.487	undefined	undefined	0.832
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	3.6583	60.368	undefined	undefined	0.952
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.030970	0.12723	undefined	undefined	0.810
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.067288	0.10807	undefined	undefined	0.540
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.045892	0.088391	undefined	undefined	0.609
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	18.046	236.33	undefined	undefined	0.940
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	24.327	270.26	undefined	undefined	0.929
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	-63.071	243.29	undefined	undefined	0.798
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	-15.294	217.68	undefined	undefined	0.945
startle / PPI	maximum baseline movement during background noise	-5.9229	4.2022	undefined	undefined	0.173
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-3.4995	12.926	undefined	undefined	0.789
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	4.7879	10.438	undefined	undefined	0.651
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	1.3827	8.3609	undefined	undefined	0.870
startle / PPI	maximum startle response to full pulse (120 dB)	12.123	234.78	undefined	undefined	0.959
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	26.213	272.20	undefined	undefined	0.924
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-62.267	241.67	undefined	undefined	0.799
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-13.181	213.67	undefined	undefined	0.951
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	1.8854	6.0254	undefined	undefined	0.757
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	0.80417	4.5540	undefined	undefined	0.861
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	2.1125	10.922	undefined	undefined	0.848

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Sex	Trait Effect	P-value
eye morphology	anterior chamber depth	females	1.0 %	1.0
eye morphology	anterior chamber depth	males	0.0 %	1.0
eye morphology	anterior chamber depth	both	1.0 %	1.0
eye morphology	bulging eye	females	1.0 %	1.0
eye morphology	bulging eye	males	0.0 %	1.0
eye morphology	bulging eye	both	1.0 %	1.00
eye morphology	cornea	females	4.0 %	1.0
eye morphology	cornea	males	2.0 %	1.0
eye morphology	cornea	both	3.0 %	1.00
eye morphology	cornea opacity	females	5.0 %	1.00
eye morphology	cornea opacity	males	1.0 %	1.0
eye morphology	cornea opacity	both	3.0 %	1.00
eye morphology	cornea vascularization	females	3.0 %	1.0
eye morphology	cornea vascularization	males	1.0 %	1.0
eye morphology	cornea vascularization	both	2.0 %	1.00
eye morphology	corneal deposits	females	2.0 %	1.0
eye morphology	corneal deposits	males	1.0 %	1.0
eye morphology	corneal deposits	both	1.0 %	1.00
eye morphology	corneal mineralization	females	2.0 %	1.0
eye morphology	corneal mineralization	males	1.0 %	1.0
eye morphology	corneal mineralization	both	1.0 %	1.00
eye morphology	corneal scleralization	females	3.0 %	1.00
eye morphology	corneal scleralization	males	1.0 %	1.0
eye morphology	corneal scleralization	both	2.0 %	1.00
eye morphology	corneal ulcer	females	1.0 %	1.0
eye morphology	corneal ulcer	males	1.0 %	1.0
eye morphology	corneal ulcer	both	1.0 %	1.00
eye morphology	eye closure	females	1.0 %	1.00
eye morphology	eye closure	males	0.0 %	1.0
eye morphology	eye closure	both	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	females	2.0 %	1.00
eye morphology	eye hemorrhage or blood presence	males	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	both	1.0 %	1.00
eye morphology	eyelid morphology	females	1.0 %	1.0
eye morphology	eyelid morphology	males	0.0 %	1.0
eye morphology	eyelid morphology	both	1.0 %	1.0
eye morphology	eyes (present, absent)	females	1.0 %	1.0
eye morphology	eyes (present, absent)	males	0.0 %	1.0
eye morphology	eyes (present, absent)	both	0.0 %	1.0
eye morphology	fusion between cornea and lens	females	4.0 %	1.00
eye morphology	fusion between cornea and lens	males	2.0 %	1.0
eye morphology	fusion between cornea and lens	both	3.0 %	1.00
eye morphology	iris pigmentation	females	2.0 %	1.0
eye morphology	iris pigmentation	males	1.0 %	1.0
eye morphology	iris pigmentation	both	2.0 %	1.00
eye morphology	iris transillumination	females	2.0 %	1.00
eye morphology	iris transillumination	males	1.0 %	1.0
eye morphology	iris transillumination	both	1.0 %	1.00
eye morphology	irispupil	females	4.0 %	1.00
eye morphology	irispupil	males	3.0 %	1.0
eye morphology	irispupil	both	3.0 %	1.00
eye morphology	lacrimation	females	3.0 %	1.0
eye morphology	lacrimation	males	2.0 %	1.0
eye morphology	lacrimation	both	3.0 %	1.0
eye morphology	lens	females	10.0 %	1.00
eye morphology	lens	males	8.0 %	1.0
eye morphology	lens	both	9.0 %	1.0
eye morphology	lens opacity	females	9.0 %	0.531
eye morphology	lens opacity	males	10.0 %	0.368
eye morphology	lens opacity	both	10.0 %	0.320
eye morphology	narrow eye opening	females	2.0 %	1.0
eye morphology	narrow eye opening	males	1.0 %	1.0
eye morphology	narrow eye opening	both	1.0 %	1.0
eye morphology	optic disc	females	4.0 %	1.00
eye morphology	optic disc	males	2.0 %	1.0
eye morphology	optic disc	both	3.0 %	1.00
eye morphology	persistence of hyaloid vascular system	females	14.0 %	1.0
eye morphology	persistence of hyaloid vascular system	males	5.0 %	1.0
eye morphology	persistence of hyaloid vascular system	both	9.0 %	1.00
eye morphology	pupil dilation	females	2.0 %	1.0
eye morphology	pupil dilation	males	1.0 %	1.0
eye morphology	pupil dilation	both	2.0 %	1.0
eye morphology	pupil light response	females	2.0 %	1.00
eye morphology	pupil light response	males	1.0 %	1.0
eye morphology	pupil light response	both	2.0 %	1.00
eye morphology	pupil position	females	4.0 %	1.00
eye morphology	pupil position	males	3.0 %	1.0
eye morphology	pupil position	both	4.0 %	1.00
eye morphology	pupil shape	females	3.0 %	1.00
eye morphology	pupil shape	males	2.0 %	1.0
eye morphology	pupil shape	both	3.0 %	1.00
eye morphology	retina	females	10.0 %	0.560
eye morphology	retina	males	7.0 %	0.750
eye morphology	retina	both	8.0 %	0.589
eye morphology	retinal blood vessels	females	4.0 %	1.0
eye morphology	retinal blood vessels	males	2.0 %	1.0
eye morphology	retinal blood vessels	both	3.0 %	1.0
eye morphology	retinal blood vessels pattern	females	5.0 %	1.0
eye morphology	retinal blood vessels pattern	males	12.0 %	0.0346
eye morphology	retinal blood vessels pattern	both	6.0 %	0.173
eye morphology	retinal blood vessels structure	females	4.0 %	1.00
eye morphology	retinal blood vessels structure	males	2.0 %	1.0
eye morphology	retinal blood vessels structure	both	3.0 %	1.00
eye morphology	retinal pigmentation	females	12.0 %	1.0
eye morphology	retinal pigmentation	males	14.0 %	1.0
eye morphology	retinal pigmentation	both	13.0 %	1.0
eye morphology	retinal structure	females	4.0 %	1.00
eye morphology	retinal structure	males	2.0 %	1.0
eye morphology	retinal structure	both	3.0 %	1.00
eye morphology	synechia	females	4.0 %	1.0
eye morphology	synechia	males	2.0 %	1.0
eye morphology	synechia	both	3.0 %	1.00
eye morphology	vitreous	females	4.0 %	1.00
eye morphology	vitreous	males	2.0 %	1.0
eye morphology	vitreous	both	3.0 %	1.00
SHIRPA	activity body position	females	1.0 %	1.0
SHIRPA	activity body position	males	2.0 %	1.0
SHIRPA	activity body position	both	1.0 %	1.00
SHIRPA	aggression	females	0.0 %	1.00
SHIRPA	aggression	males	1.0 %	1.0
SHIRPA	aggression	both	1.0 %	1.00
SHIRPA	body length	females	0.0 %	1.00
SHIRPA	body length	males	0.0 %	1.0
SHIRPA	body length	both	0.0 %	1.0
SHIRPA	body position	females	0.0 %	1.00
SHIRPA	body position	males	1.0 %	1.0
SHIRPA	body position	both	0.0 %	1.0
SHIRPA	body thickness	females	1.0 %	1.00
SHIRPA	body thickness	males	0.0 %	1.0
SHIRPA	body thickness	both	0.0 %	1.0
SHIRPA	coat color abdomen	females	3.0 %	1.00
SHIRPA	coat color abdomen	males	4.0 %	1.0
SHIRPA	coat color abdomen	both	4.0 %	1.0
SHIRPA	coat color back	females	0.0 %	1.00
SHIRPA	coat color back	males	0.0 %	1.0
SHIRPA	coat color back	both	0.0 %	1.00
SHIRPA	coat color head	females	0.0 %	1.00
SHIRPA	coat color head	males	0.0 %	1.0
SHIRPA	coat color head	both	0.0 %	1.00
SHIRPA	coat color pattern abdomen	females	1.0 %	1.00
SHIRPA	coat color pattern abdomen	males	1.0 %	1.0
SHIRPA	coat color pattern abdomen	both	1.0 %	1.00
SHIRPA	coat color pattern back	females	0.0 %	1.00
SHIRPA	coat color pattern back	males	0.0 %	1.0
SHIRPA	coat color pattern back	both	0.0 %	1.00
SHIRPA	coat color pattern head	females	0.0 %	1.00
SHIRPA	coat color pattern head	males	0.0 %	1.0
SHIRPA	coat color pattern head	both	0.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	females	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	males	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	both	2.0 %	1.0
SHIRPA	coat hair back texture appearance	females	0.0 %	1.00
SHIRPA	coat hair back texture appearance	males	0.0 %	1.0
SHIRPA	coat hair back texture appearance	both	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	females	0.0 %	1.00
SHIRPA	coat hair distribution abdomen	males	1.0 %	1.0
SHIRPA	coat hair distribution abdomen	both	1.0 %	1.00
SHIRPA	coat hair distribution back	females	0.0 %	1.00
SHIRPA	coat hair distribution back	males	0.0 %	1.0
SHIRPA	coat hair distribution back	both	0.0 %	1.00
SHIRPA	coat hair distribution head	females	1.0 %	1.00
SHIRPA	coat hair distribution head	males	1.0 %	1.0
SHIRPA	coat hair distribution head	both	1.0 %	1.0
SHIRPA	coat hair head texture appearance	females	0.0 %	1.00
SHIRPA	coat hair head texture appearance	males	0.0 %	1.0
SHIRPA	coat hair head texture appearance	both	0.0 %	1.0
SHIRPA	contact righting	females	5.0 %	1.0
SHIRPA	contact righting	males	5.0 %	1.0
SHIRPA	contact righting	both	5.0 %	1.00
SHIRPA	ear morphology	females	0.0 %	1.0
SHIRPA	ear morphology	males	0.0 %	1.0
SHIRPA	ear morphology	both	0.0 %	1.0
SHIRPA	fat distribution	females	0.0 %	1.00
SHIRPA	fat distribution	males	0.0 %	1.0
SHIRPA	fat distribution	both	0.0 %	1.0
SHIRPA	forelimb digit number	females	0.0 %	1.00
SHIRPA	forelimb digit number	males	0.0 %	1.0
SHIRPA	forelimb digit number	both	0.0 %	1.00
SHIRPA	forelimb digit position	females	0.0 %	1.0
SHIRPA	forelimb digit position	males	0.0 %	1.0
SHIRPA	forelimb digit position	both	0.0 %	1.0
SHIRPA	forelimb digit shape	females	0.0 %	1.0
SHIRPA	forelimb digit shape	males	0.0 %	1.0
SHIRPA	forelimb digit shape	both	0.0 %	1.0
SHIRPA	forelimb digit size	females	0.0 %	1.0
SHIRPA	forelimb digit size	males	0.0 %	1.0
SHIRPA	forelimb digit size	both	0.0 %	1.0
SHIRPA	forelimb footpads	females	0.0 %	1.00
SHIRPA	forelimb footpads	males	0.0 %	1.0
SHIRPA	forelimb footpads	both	0.0 %	1.0
SHIRPA	forelimb nail length	females	0.0 %	1.0
SHIRPA	forelimb nail length	males	0.0 %	1.0
SHIRPA	forelimb nail length	both	0.0 %	1.0
SHIRPA	forelimb nail number	females	0.0 %	1.0
SHIRPA	forelimb nail number	males	0.0 %	1.0
SHIRPA	forelimb nail number	both	0.0 %	1.0
SHIRPA	forelimb nail position	females	0.0 %	1.0
SHIRPA	forelimb nail position	males	0.0 %	1.0
SHIRPA	forelimb nail position	both	0.0 %	1.0
SHIRPA	forelimb nail shape	females	0.0 %	1.0
SHIRPA	forelimb nail shape	males	0.0 %	1.0
SHIRPA	forelimb nail shape	both	0.0 %	1.0
SHIRPA	forelimbs position	females	0.0 %	1.0
SHIRPA	forelimbs position	males	0.0 %	1.0
SHIRPA	forelimbs position	both	0.0 %	1.0
SHIRPA	forelimbs shape	females	0.0 %	1.0
SHIRPA	forelimbs shape	males	0.0 %	1.0
SHIRPA	forelimbs shape	both	0.0 %	1.0
SHIRPA	forelimbs size	females	0.0 %	1.00
SHIRPA	forelimbs size	males	0.0 %	1.0
SHIRPA	forelimbs size	both	0.0 %	1.0
SHIRPA	forepaw position	females	0.0 %	1.0
SHIRPA	forepaw position	males	0.0 %	1.0
SHIRPA	forepaw position	both	0.0 %	1.0
SHIRPA	forepaw shape	females	0.0 %	1.0
SHIRPA	forepaw shape	males	0.0 %	1.0
SHIRPA	forepaw shape	both	0.0 %	1.0
SHIRPA	forepaw size	females	0.0 %	1.0
SHIRPA	forepaw size	males	0.0 %	1.0
SHIRPA	forepaw size	both	0.0 %	1.0
SHIRPA	gait (fluidity)	females	0.0 %	1.0
SHIRPA	gait (fluidity)	males	0.0 %	1.0
SHIRPA	gait (fluidity)	both	0.0 %	1.0
SHIRPA	genitalia morphology	females	0.0 %	1.00
SHIRPA	genitalia morphology	males	0.0 %	1.0
SHIRPA	genitalia morphology	both	0.0 %	1.00
SHIRPA	genitalia presence	females	0.0 %	1.00
SHIRPA	genitalia presence	males	0.0 %	1.0
SHIRPA	genitalia presence	both	0.0 %	1.0
SHIRPA	genitalia size	females	0.0 %	1.0
SHIRPA	genitalia size	males	0.0 %	1.0
SHIRPA	genitalia size	both	0.0 %	1.00
SHIRPA	head bobbing	females	0.0 %	1.0
SHIRPA	head bobbing	males	0.0 %	1.0
SHIRPA	head bobbing	both	0.0 %	1.0
SHIRPA	head morphology	females	0.0 %	1.00
SHIRPA	head morphology	males	0.0 %	1.0
SHIRPA	head morphology	both	0.0 %	1.0
SHIRPA	head size	females	0.0 %	1.0
SHIRPA	head size	males	0.0 %	1.0
SHIRPA	head size	both	0.0 %	1.00
SHIRPA	hindlimb digit number	females	1.0 %	1.00
SHIRPA	hindlimb digit number	males	0.0 %	1.0
SHIRPA	hindlimb digit number	both	0.0 %	1.00
SHIRPA	hindlimb digit position	females	0.0 %	1.00
SHIRPA	hindlimb digit position	males	0.0 %	1.0
SHIRPA	hindlimb digit position	both	0.0 %	1.0
SHIRPA	hindlimb digit shape	females	0.0 %	1.00
SHIRPA	hindlimb digit shape	males	0.0 %	1.0
SHIRPA	hindlimb digit shape	both	0.0 %	1.00
SHIRPA	hindlimb digit size	females	0.0 %	1.00
SHIRPA	hindlimb digit size	males	0.0 %	1.0
SHIRPA	hindlimb digit size	both	0.0 %	1.00
SHIRPA	hindlimb nail length	females	0.0 %	1.0
SHIRPA	hindlimb nail length	males	0.0 %	1.0
SHIRPA	hindlimb nail length	both	0.0 %	1.00
SHIRPA	hindlimb nail number	females	0.0 %	1.0
SHIRPA	hindlimb nail number	males	24.0 %	0.0294
SHIRPA	hindlimb nail number	both	12.0 %	0.0321
SHIRPA	hindlimb nail position	females	0.0 %	1.0
SHIRPA	hindlimb nail position	males	0.0 %	1.0
SHIRPA	hindlimb nail position	both	0.0 %	1.0
SHIRPA	hindlimb nail shape	females	0.0 %	1.0
SHIRPA	hindlimb nail shape	males	0.0 %	1.0
SHIRPA	hindlimb nail shape	both	0.0 %	1.0
SHIRPA	hindlimbs footpads	females	0.0 %	1.00
SHIRPA	hindlimbs footpads	males	0.0 %	1.0
SHIRPA	hindlimbs footpads	both	0.0 %	1.0
SHIRPA	hindlimbs position	females	0.0 %	1.0
SHIRPA	hindlimbs position	males	0.0 %	1.0
SHIRPA	hindlimbs position	both	0.0 %	1.0
SHIRPA	hindlimbs shape	females	0.0 %	1.0
SHIRPA	hindlimbs shape	males	0.0 %	1.0
SHIRPA	hindlimbs shape	both	0.0 %	1.0
SHIRPA	hindlimbs size	females	0.0 %	1.0
SHIRPA	hindlimbs size	males	0.0 %	1.0
SHIRPA	hindlimbs size	both	0.0 %	1.0
SHIRPA	hindpaw position	females	0.0 %	1.0
SHIRPA	hindpaw position	males	0.0 %	1.0
SHIRPA	hindpaw position	both	0.0 %	1.0
SHIRPA	hindpaw shape	females	0.0 %	1.00
SHIRPA	hindpaw shape	males	0.0 %	1.0
SHIRPA	hindpaw shape	both	0.0 %	1.0
SHIRPA	hindpaw size	females	0.0 %	1.00
SHIRPA	hindpaw size	males	0.0 %	1.0
SHIRPA	hindpaw size	both	0.0 %	1.0
SHIRPA	limb grasp	females	9.0 %	1.00
SHIRPA	limb grasp	males	6.0 %	1.0
SHIRPA	limb grasp	both	7.0 %	1.0
SHIRPA	lower lip morphology	females	0.0 %	1.00
SHIRPA	lower lip morphology	males	0.0 %	1.0
SHIRPA	lower lip morphology	both	0.0 %	1.0
SHIRPA	lower teeth appearance	females	0.0 %	1.0
SHIRPA	lower teeth appearance	males	0.0 %	1.0
SHIRPA	lower teeth appearance	both	0.0 %	1.0
SHIRPA	mouth morphology	females	0.0 %	1.0
SHIRPA	mouth morphology	males	0.0 %	1.0
SHIRPA	mouth morphology	both	0.0 %	1.0
SHIRPA	salivation	females	0.0 %	1.0
SHIRPA	salivation	males	0.0 %	1.0
SHIRPA	salivation	both	0.0 %	1.0
SHIRPA	skin color back paws	females	0.0 %	1.0
SHIRPA	skin color back paws	males	0.0 %	1.0
SHIRPA	skin color back paws	both	0.0 %	1.0
SHIRPA	skin color ear	females	0.0 %	1.0
SHIRPA	skin color ear	males	0.0 %	1.0
SHIRPA	skin color ear	both	0.0 %	1.0
SHIRPA	skin color front paws	females	0.0 %	1.0
SHIRPA	skin color front paws	males	0.0 %	1.0
SHIRPA	skin color front paws	both	0.0 %	1.0
SHIRPA	skin color snout	females	0.0 %	1.0
SHIRPA	skin color snout	males	0.0 %	1.0
SHIRPA	skin color snout	both	0.0 %	1.0
SHIRPA	skin color tail	females	0.0 %	1.0
SHIRPA	skin color tail	males	0.0 %	1.0
SHIRPA	skin color tail	both	0.0 %	1.0
SHIRPA	skin color whole body	females	0.0 %	1.00
SHIRPA	skin color whole body	males	0.0 %	1.0
SHIRPA	skin color whole body	both	0.0 %	1.0
SHIRPA	skin texture back paw	females	0.0 %	1.0
SHIRPA	skin texture back paw	males	0.0 %	1.0
SHIRPA	skin texture back paw	both	0.0 %	1.0
SHIRPA	skin texture ear	females	0.0 %	1.0
SHIRPA	skin texture ear	males	0.0 %	1.0
SHIRPA	skin texture ear	both	0.0 %	1.0
SHIRPA	skin texture front paws	females	0.0 %	1.0
SHIRPA	skin texture front paws	males	0.0 %	1.0
SHIRPA	skin texture front paws	both	0.0 %	1.0
SHIRPA	skin texture snout	females	0.0 %	1.0
SHIRPA	skin texture snout	males	0.0 %	1.0
SHIRPA	skin texture snout	both	0.0 %	1.0
SHIRPA	skin texture tail	females	0.0 %	1.0
SHIRPA	skin texture tail	males	0.0 %	1.0
SHIRPA	skin texture tail	both	0.0 %	1.0
SHIRPA	skin texture whole body	females	0.0 %	1.0
SHIRPA	skin texture whole body	males	0.0 %	1.0
SHIRPA	skin texture whole body	both	0.0 %	1.00
SHIRPA	snout size	females	0.0 %	1.00
SHIRPA	snout size	males	1.0 %	1.00
SHIRPA	snout size	both	0.0 %	1.0
SHIRPA	startle response	females	0.0 %	1.0
SHIRPA	startle response	males	0.0 %	1.00
SHIRPA	startle response	both	0.0 %	1.00
SHIRPA	tail curvature	females	0.0 %	1.0
SHIRPA	tail curvature	males	0.0 %	1.0
SHIRPA	tail curvature	both	0.0 %	1.0
SHIRPA	tail elevation	females	1.0 %	1.00
SHIRPA	tail elevation	males	2.0 %	1.0
SHIRPA	tail elevation	both	1.0 %	1.0
SHIRPA	tail length	females	0.0 %	1.00
SHIRPA	tail length	males	0.0 %	1.0
SHIRPA	tail length	both	0.0 %	1.0
SHIRPA	tail morphology	females	0.0 %	1.00
SHIRPA	tail morphology	males	0.0 %	1.0
SHIRPA	tail morphology	both	0.0 %	1.00
SHIRPA	tail presence	females	0.0 %	1.0
SHIRPA	tail presence	males	0.0 %	1.0
SHIRPA	tail presence	both	0.0 %	1.0
SHIRPA	tail shape	females	0.0 %	1.00
SHIRPA	tail shape	males	0.0 %	1.0
SHIRPA	tail shape	both	0.0 %	1.0
SHIRPA	tail thickness	females	0.0 %	1.0
SHIRPA	tail thickness	males	0.0 %	1.0
SHIRPA	tail thickness	both	0.0 %	1.0
SHIRPA	teeth presence	females	0.0 %	1.00
SHIRPA	teeth presence	males	0.0 %	1.0
SHIRPA	teeth presence	both	0.0 %	1.0
SHIRPA	transfer arousal	females	1.0 %	1.0
SHIRPA	transfer arousal	males	2.0 %	1.0
SHIRPA	transfer arousal	both	1.0 %	1.0
SHIRPA	tremor	females	0.0 %	1.00
SHIRPA	tremor	males	0.0 %	1.0
SHIRPA	tremor	both	0.0 %	1.0
SHIRPA	trunk curl	females	0.0 %	1.00
SHIRPA	trunk curl	males	0.0 %	1.0
SHIRPA	trunk curl	both	0.0 %	1.00
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	females	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	males	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	both	0.0 %	1.00
SHIRPA	upper lip morphology	females	0.0 %	1.0
SHIRPA	upper lip morphology	males	0.0 %	1.0
SHIRPA	upper lip morphology	both	0.0 %	1.0
SHIRPA	upper teeth appearance	females	25.0 %	0.00294
SHIRPA	upper teeth appearance	males	0.0 %	1.0
SHIRPA	upper teeth appearance	both	12.0 %	0.00737
SHIRPA	vibrissae appearance	females	2.0 %	1.0
SHIRPA	vibrissae appearance	males	1.0 %	1.0
SHIRPA	vibrissae appearance	both	1.0 %	1.0
SHIRPA	vibrissae presence	females	2.0 %	1.0
SHIRPA	vibrissae presence	males	1.0 %	1.00
SHIRPA	vibrissae presence	both	2.0 %	1.0
SHIRPA	vocalization	females	2.0 %	1.00
SHIRPA	vocalization	males	2.0 %	1.00
SHIRPA	vocalization	both	2.0 %	1.0

GENOTYPE CORRELATION PLOT

Correlate Fbxo3^em1(IMPC)J/Mmjax -/+ with genotype: