MPD: JaxKOMP-EAP genotype: Chmp1b<sup>em1(IMPC)J</sup>/Mmjax -/-

JaxKOMP-EAP effect sizes: Chmp1b^em1(IMPC)J/Mmjax -/- Gene Chmp1b

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	-2.5000	1.2127	undefined	undefined	0.0570
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	-0.20833	2.0778	undefined	undefined	0.921
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	-4.3750	4.3168	undefined	undefined	0.327
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	-1.4583	3.4385	undefined	undefined	0.678
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	-2.3785	2.7888	undefined	undefined	0.408
body composition	body length	-0.074952	0.048672	undefined	undefined	0.132
body composition	body weight (at time of DXA)	-0.66267	0.65442	undefined	undefined	0.318
body composition	bone area, whole body scan, head excluded	0.13946	0.16728	undefined	undefined	0.410
body composition	bone mineral content of whole body scan, head excluded	0.010085	0.011837	undefined	undefined	0.400
body composition	bone mineral content to body weight ratio	0.00063726	0.00047069	undefined	undefined	0.184
body composition	bone mineral density of whole body scan, head excluded	0.00041123	0.00050641	undefined	undefined	0.422
body composition	fat tissue mass of whole body scan, head excluded	-0.073563	0.33843	undefined	undefined	0.829
body composition	fat tissue mass to body weight ratio	-0.0066922	0.011621	undefined	undefined	0.568
body composition	lean tissue mass of whole body scan, head excluded	0.34848	0.27934	undefined	undefined	0.220
body composition	lean tissue mass to body weight ratio	0.010642	0.010163	undefined	undefined	0.302
body composition	percent fat, whole body scan, head excluded	-0.86221	1.0605	undefined	undefined	0.421
body composition	ratio of soft-tissue attenuation coefficients	0.00086527	0.0011792	undefined	undefined	0.468
body composition	tissue area	-0.034127	0.20323	undefined	undefined	0.868
body composition	total tissue mass, whole body scan, head excluded	0.12834	0.24334	undefined	undefined	0.601
clinical blood chemistry	alanine transaminase (plasma ALT)	-45.023	25.209	undefined	undefined	0.0828
clinical blood chemistry	albumin (plasma Alb)	0.30059	0.37281	undefined	undefined	0.426
clinical blood chemistry	alkaline phosphatase (plasma ALP)	-0.25258	3.1981	undefined	undefined	0.937
clinical blood chemistry	aspartate transaminase (plasma AST)	-93.083	46.410	undefined	undefined	0.0527
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	-0.018735	0.19496	undefined	undefined	0.924
clinical blood chemistry	blood urea nitrogen (BUN)	-2.4460	1.1042	undefined	undefined	0.0334
clinical blood chemistry	calcium (plasma Ca)	-0.072553	0.077281	undefined	undefined	0.354
clinical blood chemistry	creatinine (plasma)	-0.048791	0.032448	undefined	undefined	0.142
clinical blood chemistry	glucose (plasma GLU, no fast)	22.272	10.133	undefined	undefined	0.0347
clinical blood chemistry	HDL cholesterol (plasma HDL)	7.9147	2.4787	undefined	undefined	0.00303
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	0.026807	0.012607	undefined	undefined	0.0406
clinical blood chemistry	phosphorus (plasma phosphate)	-0.91891	0.43878	undefined	undefined	0.0438
clinical blood chemistry	total bilirubin (plasma TBIL)	-0.024556	0.014153	undefined	undefined	0.0915
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	7.7898	3.6768	undefined	undefined	0.0415
clinical blood chemistry	total protein (plasma TP)	0.39868	0.60290	undefined	undefined	0.513
clinical blood chemistry	triglyceride (plasma TG, no fast)	-31.066	18.860	undefined	undefined	0.108
glucose tolerance test	amount glucose injected	-3.9074	1.6726	undefined	undefined	0.0225
glucose tolerance test	plasma glucose, 0min	11.609	3.1033	undefined	undefined	0.000386
glucose tolerance test	plasma glucose, 15min	48.932	14.811	undefined	undefined	0.00153
glucose tolerance test	plasma glucose, 30min	23.564	13.299	undefined	undefined	0.0810
glucose tolerance test	plasma glucose, 60min	2.6373	9.8209	undefined	undefined	0.789
glucose tolerance test	plasma glucose, 120min	0.54419	5.8760	undefined	undefined	0.926
grip strength	body weight (at time of grip strength test)	-0.97558	0.38347	undefined	undefined	0.0139
grip strength	forelimb and hindlimb grip strength (mean of trials), average	1.0462	3.8303	undefined	undefined	0.786
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	0.18174	0.20324	undefined	undefined	0.375
grip strength	forelimb and hindlimb grip strength by trial, trial1	-1.2378	4.1233	undefined	undefined	0.765
grip strength	forelimb and hindlimb grip strength by trial, trial2	0.60479	4.4991	undefined	undefined	0.894
grip strength	forelimb and hindlimb grip strength by trial, trial3	2.4122	4.7423	undefined	undefined	0.613
grip strength	forelimb grip strength (mean of trials), average	-0.59151	2.4164	undefined	undefined	0.808
grip strength	forelimb grip strength (mean of trials), average normalized to bw	0.077409	0.11325	undefined	undefined	0.497
grip strength	forelimb grip strength by trial, trial1	-2.4116	2.9623	undefined	undefined	0.419
grip strength	forelimb grip strength by trial, trial2	-0.093435	2.7448	undefined	undefined	0.973
grip strength	forelimb grip strength by trial, trial3	0.47112	3.2322	undefined	undefined	0.885
heart weight	heart weight, normalized to body weight	0.14819	0.15875	undefined	undefined	0.355
heart weight	heart weight, weight	-0.041210	5.1420	undefined	undefined	0.994
hematology	basophil differential (percent of total WBC)	-0.20143	0.14139	undefined	undefined	0.165
hematology	eosinophil differential (percent of total WBC)	-0.76714	0.60037	undefined	undefined	0.211
hematology	hematocrit (HCT)	1.3905	0.55069	undefined	undefined	0.0175
hematology	lymphocyte differential (percent of total WBC)	3.0844	1.6401	undefined	undefined	0.0701
hematology	mean corpuscular hemoglobin (CHr)	0.047922	0.056159	undefined	undefined	0.400
hematology	mean platelet volume (MPV)	-0.19012	0.093742	undefined	undefined	0.0518
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	0.15681	0.19956	undefined	undefined	0.438
hematology	mean RBC corpuscular volume (MCV)	-0.23544	0.33044	undefined	undefined	0.482
hematology	measured hemoglobin (mHGB)	0.72999	0.20232	undefined	undefined	0.00115
hematology	monocyte differential (percent of total WBC)	-0.28097	0.26459	undefined	undefined	0.297
hematology	neutrophil differential (percent of total WBC)	-1.9946	1.0898	undefined	undefined	0.0775
hematology	platelet count (PLT; units per volume x 10³)	151.47	94.516	undefined	undefined	0.120
hematology	RBC corpuscular distribution width (RDW)	0.37750	0.16329	undefined	undefined	0.0281
hematology	red blood cell count (RBC; per volume x 10⁶)	0.42744	0.15657	undefined	undefined	0.0107
hematology	reticulocyte count (Retic; units per volume x 10⁹)	-9.3006	20.969	undefined	undefined	0.661
hematology	reticulocyte differential (percent of total RBC)	-0.25580	0.24726	undefined	undefined	0.309
hematology	white blood cell count (WBC; units per volume x 10³)	2.1790	0.74105	undefined	undefined	0.00638
holeboard	number of hole pokes by individual hole number, 20 min test, 1	-0.93750	0.95142	undefined	undefined	0.328
holeboard	number of hole pokes by individual hole number, 20 min test, 2	-1.1821	0.71218	undefined	undefined	0.102
holeboard	number of hole pokes by individual hole number, 20 min test, 3	-0.89485	0.63917	undefined	undefined	0.166
holeboard	number of hole pokes by individual hole number, 20 min test, 4	-3.3508	0.98764	undefined	undefined	0.00116
holeboard	number of hole pokes by individual hole number, 20 min test, 5	-1.2958	0.57693	undefined	undefined	0.0280
holeboard	number of hole pokes by individual hole number, 20 min test, 6	-0.52967	0.46607	undefined	undefined	0.260
holeboard	number of hole pokes by individual hole number, 20 min test, 7	-1.0708	0.38011	undefined	undefined	0.00634
holeboard	number of hole pokes by individual hole number, 20 min test, 8	-1.0083	0.54333	undefined	undefined	0.0678
holeboard	number of hole pokes by individual hole number, 20 min test, 9	-0.33627	0.55906	undefined	undefined	0.550
holeboard	number of hole pokes by individual hole number, 20 min test, 10	-0.56667	0.52096	undefined	undefined	0.281
holeboard	number of hole pokes by individual hole number, 20 min test, 11	-0.87665	0.46048	undefined	undefined	0.0612
holeboard	number of hole pokes by individual hole number, 20 min test, 12	-1.2548	0.59416	undefined	undefined	0.0384
holeboard	number of hole pokes by individual hole number, 20 min test, 13	-2.8872	0.92268	undefined	undefined	0.00260
holeboard	number of hole pokes by individual hole number, 20 min test, 14	-1.4426	0.54146	undefined	undefined	0.00963
holeboard	number of hole pokes by individual hole number, 20 min test, 15	-0.69174	0.70739	undefined	undefined	0.332
holeboard	number of hole pokes by individual hole number, 20 min test, 16	-2.6958	1.0934	undefined	undefined	0.0162
holeboard	total number of hole pokes, 20 min test	-21.283	6.1121	undefined	undefined	0.000874
light / dark	latency to enter dark zone, 20 min test	50.305	33.316	undefined	undefined	0.136
light / dark	number of transitions between light and dark zones, 20 min test	-16.053	4.8639	undefined	undefined	0.00155
light / dark	percentage of total time in dark zone, 20 min test	-7.3159	5.2169	undefined	undefined	0.165
light / dark	percentage of total time in light zone, 20 min test	7.3162	5.2169	undefined	undefined	0.165
light / dark	time mobile in dark zone, 20 min test	-13.149	5.4365	undefined	undefined	0.0183
light / dark	time mobile in light zone, 20 min test	1.1348	4.7202	undefined	undefined	0.811
light / dark	time spent in dark zone, 20 min test	-111.87	60.141	undefined	undefined	0.0673
light / dark	time spent in light zone, 20 min test	111.87	60.141	undefined	undefined	0.0673
open field	average speed in center of arena, 20 min test	-0.73518	0.30324	undefined	undefined	0.0180
open field	average speed in periphery of arena, 20 min test	-0.58043	0.14784	undefined	undefined	0.000206
open field	distance traveled habituation ratio, 20 min test	-6.6863	7.8087	undefined	undefined	0.395
open field	distance traveled in center of arena, 20 min test	-150.89	117.98	undefined	undefined	0.205
open field	distance traveled in periphery of arena, 20 min test	-561.68	148.66	undefined	undefined	0.000338
open field	distance traveled slope, 20 min test	-6.4890	7.5125	undefined	undefined	0.391
open field	distance traveled, 20 min test, 1st 5min	-95.474	79.156	undefined	undefined	0.232
open field	distance traveled, 20 min test, 2nd 5min	-210.55	53.617	undefined	undefined	0.000206
open field	distance traveled, 20 min test, 3rd 5min	-239.86	54.248	undefined	undefined	0.0000368
open field	distance traveled, 20 min test, 4th 5min	-205.31	50.820	undefined	undefined	0.000140
open field	number of clockwise revolution episodes, 20 min test	-5.2443	1.4501	undefined	undefined	0.000573
open field	number of counter-clockwise revolution episodes, 20 min test	-1.4445	1.2749	undefined	undefined	0.261
open field	number of rears in 5 min bins, 20 min test, 1st 5min	-5.2000	2.8566	undefined	undefined	0.0731
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	-8.5770	3.5621	undefined	undefined	0.0188
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	-6.0125	2.9025	undefined	undefined	0.0421
open field	number of rears in 5 min bins, 20 min test, 4th 5min	-7.9125	3.3085	undefined	undefined	0.0195
open field	percentage of total time in center of arena, 20 min test	2.7821	3.4023	undefined	undefined	0.416
open field	percentage of total time in center of arena, slope, 20 min test	-0.40853	1.3504	undefined	undefined	0.763
open field	percentage of total time in center, habituation ratio, 20 min test	-0.75851	1.5265	undefined	undefined	0.621
open field	percentage of total time in corners of arena, 20 min test	-1.6723	2.4763	undefined	undefined	0.502
open field	percentage of total time in corners, habituation ratio, 20 min test	1.0552	1.5544	undefined	undefined	0.500
open field	percentage of total time in corners, slope, 20 min test	0.97038	1.5010	undefined	undefined	0.520
open field	permanence time in center of arena, 20 min test	33.377	40.828	undefined	undefined	0.417
open field	permanence time in corners of arena, 20 min test	-20.057	29.717	undefined	undefined	0.502
open field	permanence time in periphery of arena, 20 min test	-33.377	40.828	undefined	undefined	0.416
open field	total distance traveled, 20 min test	-765.00	204.92	undefined	undefined	0.000392
open field	total number of rears, 20 min test	-29.062	10.591	undefined	undefined	0.00775
open field	whole arena average speed, 20 min test	-0.63616	0.17085	undefined	undefined	0.000405
open field	whole arena resting time, 20 min test	63.606	20.286	undefined	undefined	0.00253
open field	whole arena time spent mobile, 20 min test	-17.977	4.4473	undefined	undefined	0.000139
open field	whole arena time spent vertical, 20 min test	-17.965	6.5390	undefined	undefined	0.00768
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	-3.1925	1.2874	undefined	undefined	0.0164
startle / PPI	average baseline movement during background noise	1.6086	1.0463	undefined	undefined	0.133
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	-0.054147	0.061597	undefined	undefined	0.386
startle / PPI	average of each corrected percent pre-pulse inhibition value	-0.12710	0.062470	undefined	undefined	0.0500
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-11.359	7.2183	undefined	undefined	0.125
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-9.2446	7.4381	undefined	undefined	0.223
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-8.8868	5.7057	undefined	undefined	0.129
startle / PPI	average startle response to full pulse (120 dB)	-41.786	37.611	undefined	undefined	0.274
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-26.871	34.974	undefined	undefined	0.448
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-23.357	35.420	undefined	undefined	0.514
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-12.233	30.533	undefined	undefined	0.691
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	-0.56022	1.2752	undefined	undefined	0.663
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	-1.2362	1.4742	undefined	undefined	0.408
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	1.9810	1.7812	undefined	undefined	0.274
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.14200	0.087136	undefined	undefined	0.112
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.10954	0.085216	undefined	undefined	0.208
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-0.13105	0.064003	undefined	undefined	0.0486
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	-43.463	37.493	undefined	undefined	0.254
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	-26.210	35.366	undefined	undefined	0.464
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	-21.699	35.786	undefined	undefined	0.548
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	-12.293	29.978	undefined	undefined	0.684
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.16234	0.093086	undefined	undefined	0.0902
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.075861	0.083796	undefined	undefined	0.372
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-0.074798	0.067801	undefined	undefined	0.278
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	-135.57	134.58	undefined	undefined	0.321
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	-54.587	120.68	undefined	undefined	0.654
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	-53.983	122.98	undefined	undefined	0.663
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	-38.849	106.37	undefined	undefined	0.717
startle / PPI	maximum baseline movement during background noise	2.6783	2.8063	undefined	undefined	0.347
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-13.866	7.8574	undefined	undefined	0.0866
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-6.7217	7.6947	undefined	undefined	0.389
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-5.6144	6.2196	undefined	undefined	0.373
startle / PPI	maximum startle response to full pulse (120 dB)	-131.38	134.71	undefined	undefined	0.336
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-56.679	119.63	undefined	undefined	0.639
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-57.733	121.99	undefined	undefined	0.639
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-38.334	107.39	undefined	undefined	0.723
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	-1.7463	3.1026	undefined	undefined	0.577
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	-3.0606	3.4453	undefined	undefined	0.381
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	3.5768	4.5801	undefined	undefined	0.440

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Sex	Trait Effect	P-value
eye morphology	anterior chamber depth	females	1.0 %	1.0
eye morphology	anterior chamber depth	males	0.0 %	1.0
eye morphology	anterior chamber depth	both	1.0 %	1.0
eye morphology	bulging eye	females	1.0 %	1.0
eye morphology	bulging eye	males	0.0 %	1.0
eye morphology	bulging eye	both	1.0 %	1.00
eye morphology	cornea	females	4.0 %	1.0
eye morphology	cornea	males	2.0 %	1.0
eye morphology	cornea	both	3.0 %	1.00
eye morphology	cornea opacity	females	5.0 %	1.0
eye morphology	cornea opacity	males	1.0 %	1.0
eye morphology	cornea opacity	both	3.0 %	1.0
eye morphology	cornea vascularization	females	3.0 %	1.0
eye morphology	cornea vascularization	males	1.0 %	1.0
eye morphology	cornea vascularization	both	2.0 %	1.0
eye morphology	corneal deposits	females	2.0 %	1.0
eye morphology	corneal deposits	males	1.0 %	1.0
eye morphology	corneal deposits	both	1.0 %	1.00
eye morphology	corneal mineralization	females	20.0 %	0.0656
eye morphology	corneal mineralization	males	1.0 %	1.0
eye morphology	corneal mineralization	both	9.0 %	0.0874
eye morphology	corneal scleralization	females	3.0 %	1.0
eye morphology	corneal scleralization	males	1.0 %	1.0
eye morphology	corneal scleralization	both	2.0 %	1.0
eye morphology	corneal ulcer	females	1.0 %	1.0
eye morphology	corneal ulcer	males	1.0 %	1.0
eye morphology	corneal ulcer	both	1.0 %	1.0
eye morphology	eye closure	females	1.0 %	1.0
eye morphology	eye closure	males	0.0 %	1.0
eye morphology	eye closure	both	1.0 %	1.00
eye morphology	eye hemorrhage or blood presence	females	2.0 %	1.0
eye morphology	eye hemorrhage or blood presence	males	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	both	1.0 %	1.0
eye morphology	eyelid morphology	females	1.0 %	1.00
eye morphology	eyelid morphology	males	0.0 %	1.0
eye morphology	eyelid morphology	both	1.0 %	1.00
eye morphology	eyes (present, absent)	females	1.0 %	1.00
eye morphology	eyes (present, absent)	males	0.0 %	1.0
eye morphology	eyes (present, absent)	both	0.0 %	1.00
eye morphology	fusion between cornea and lens	females	4.0 %	1.0
eye morphology	fusion between cornea and lens	males	2.0 %	1.0
eye morphology	fusion between cornea and lens	both	3.0 %	1.0
eye morphology	iris pigmentation	females	2.0 %	1.0
eye morphology	iris pigmentation	males	1.0 %	1.0
eye morphology	iris pigmentation	both	2.0 %	1.0
eye morphology	iris transillumination	females	2.0 %	1.0
eye morphology	iris transillumination	males	1.0 %	1.00
eye morphology	iris transillumination	both	1.0 %	1.00
eye morphology	irispupil	females	4.0 %	1.0
eye morphology	irispupil	males	3.0 %	1.0
eye morphology	irispupil	both	3.0 %	1.0
eye morphology	lacrimation	females	3.0 %	1.0
eye morphology	lacrimation	males	2.0 %	1.00
eye morphology	lacrimation	both	3.0 %	1.00
eye morphology	lens	females	10.0 %	1.0
eye morphology	lens	males	8.0 %	1.00
eye morphology	lens	both	9.0 %	1.00
eye morphology	lens opacity	females	9.0 %	1.0
eye morphology	lens opacity	males	6.0 %	1.00
eye morphology	lens opacity	both	7.0 %	1.00
eye morphology	narrow eye opening	females	2.0 %	1.00
eye morphology	narrow eye opening	males	1.0 %	1.0
eye morphology	narrow eye opening	both	1.0 %	1.00
eye morphology	optic disc	females	4.0 %	1.0
eye morphology	optic disc	males	2.0 %	1.00
eye morphology	optic disc	both	3.0 %	1.00
eye morphology	persistence of hyaloid vascular system	females	14.0 %	1.0
eye morphology	persistence of hyaloid vascular system	males	5.0 %	1.0
eye morphology	persistence of hyaloid vascular system	both	9.0 %	1.00
eye morphology	pupil dilation	females	2.0 %	1.0
eye morphology	pupil dilation	males	1.0 %	1.00
eye morphology	pupil dilation	both	2.0 %	1.00
eye morphology	pupil light response	females	2.0 %	1.0
eye morphology	pupil light response	males	1.0 %	1.0
eye morphology	pupil light response	both	2.0 %	1.0
eye morphology	pupil position	females	4.0 %	1.0
eye morphology	pupil position	males	3.0 %	1.0
eye morphology	pupil position	both	4.0 %	1.0
eye morphology	pupil shape	females	3.0 %	1.0
eye morphology	pupil shape	males	2.0 %	1.0
eye morphology	pupil shape	both	3.0 %	1.0
eye morphology	retina	females	10.0 %	1.00
eye morphology	retina	males	16.0 %	1.0
eye morphology	retina	both	13.0 %	1.00
eye morphology	retinal blood vessels	females	4.0 %	1.0
eye morphology	retinal blood vessels	males	2.0 %	1.0
eye morphology	retinal blood vessels	both	3.0 %	1.00
eye morphology	retinal blood vessels pattern	females	5.0 %	1.0
eye morphology	retinal blood vessels pattern	males	17.0 %	0.0239
eye morphology	retinal blood vessels pattern	both	9.0 %	0.108
eye morphology	retinal blood vessels structure	females	4.0 %	1.0
eye morphology	retinal blood vessels structure	males	2.0 %	1.0
eye morphology	retinal blood vessels structure	both	3.0 %	1.0
eye morphology	retinal pigmentation	females	12.0 %	1.00
eye morphology	retinal pigmentation	males	14.0 %	1.0
eye morphology	retinal pigmentation	both	13.0 %	1.00
eye morphology	retinal structure	females	4.0 %	1.0
eye morphology	retinal structure	males	2.0 %	1.00
eye morphology	retinal structure	both	3.0 %	1.00
eye morphology	synechia	females	4.0 %	1.0
eye morphology	synechia	males	2.0 %	1.00
eye morphology	synechia	both	3.0 %	1.00
eye morphology	vitreous	females	4.0 %	1.0
eye morphology	vitreous	males	2.0 %	1.0
eye morphology	vitreous	both	3.0 %	1.0
SHIRPA	activity body position	females	1.0 %	1.0
SHIRPA	activity body position	males	2.0 %	1.0
SHIRPA	activity body position	both	1.0 %	1.00
SHIRPA	aggression	females	0.0 %	1.0
SHIRPA	aggression	males	1.0 %	1.0
SHIRPA	aggression	both	1.0 %	1.00
SHIRPA	body length	females	0.0 %	1.0
SHIRPA	body length	males	0.0 %	1.00
SHIRPA	body length	both	0.0 %	1.0
SHIRPA	body position	females	0.0 %	1.0
SHIRPA	body position	males	1.0 %	1.0
SHIRPA	body position	both	0.0 %	1.00
SHIRPA	body thickness	females	1.0 %	1.0
SHIRPA	body thickness	males	0.0 %	1.0
SHIRPA	body thickness	both	0.0 %	1.00
SHIRPA	coat color abdomen	females	3.0 %	1.0
SHIRPA	coat color abdomen	males	4.0 %	1.0
SHIRPA	coat color abdomen	both	4.0 %	1.00
SHIRPA	coat color back	females	0.0 %	1.0
SHIRPA	coat color back	males	0.0 %	1.00
SHIRPA	coat color back	both	0.0 %	1.00
SHIRPA	coat color head	females	0.0 %	1.0
SHIRPA	coat color head	males	0.0 %	1.00
SHIRPA	coat color head	both	0.0 %	1.0
SHIRPA	coat color pattern abdomen	females	1.0 %	1.0
SHIRPA	coat color pattern abdomen	males	1.0 %	1.0
SHIRPA	coat color pattern abdomen	both	1.0 %	1.00
SHIRPA	coat color pattern back	females	0.0 %	1.0
SHIRPA	coat color pattern back	males	0.0 %	1.00
SHIRPA	coat color pattern back	both	0.0 %	1.00
SHIRPA	coat color pattern head	females	0.0 %	1.0
SHIRPA	coat color pattern head	males	0.0 %	1.0
SHIRPA	coat color pattern head	both	0.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	females	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	males	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	both	2.0 %	1.0
SHIRPA	coat hair back texture appearance	females	0.0 %	1.0
SHIRPA	coat hair back texture appearance	males	0.0 %	1.0
SHIRPA	coat hair back texture appearance	both	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	females	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	males	1.0 %	1.00
SHIRPA	coat hair distribution abdomen	both	1.0 %	1.0
SHIRPA	coat hair distribution back	females	0.0 %	1.0
SHIRPA	coat hair distribution back	males	0.0 %	1.0
SHIRPA	coat hair distribution back	both	0.0 %	1.00
SHIRPA	coat hair distribution head	females	1.0 %	1.00
SHIRPA	coat hair distribution head	males	1.0 %	1.0
SHIRPA	coat hair distribution head	both	1.0 %	1.0
SHIRPA	coat hair head texture appearance	females	0.0 %	1.0
SHIRPA	coat hair head texture appearance	males	0.0 %	1.0
SHIRPA	coat hair head texture appearance	both	0.0 %	1.0
SHIRPA	contact righting	females	5.0 %	1.0
SHIRPA	contact righting	males	5.0 %	1.00
SHIRPA	contact righting	both	5.0 %	1.00
SHIRPA	ear morphology	females	0.0 %	1.0
SHIRPA	ear morphology	males	0.0 %	1.0
SHIRPA	ear morphology	both	0.0 %	1.0
SHIRPA	fat distribution	females	0.0 %	1.0
SHIRPA	fat distribution	males	0.0 %	1.0
SHIRPA	fat distribution	both	0.0 %	1.0
SHIRPA	forelimb digit number	females	0.0 %	1.0
SHIRPA	forelimb digit number	males	0.0 %	1.0
SHIRPA	forelimb digit number	both	0.0 %	1.0
SHIRPA	forelimb digit position	females	0.0 %	1.0
SHIRPA	forelimb digit position	males	0.0 %	1.0
SHIRPA	forelimb digit position	both	0.0 %	1.0
SHIRPA	forelimb digit shape	females	0.0 %	1.0
SHIRPA	forelimb digit shape	males	0.0 %	1.0
SHIRPA	forelimb digit shape	both	0.0 %	1.0
SHIRPA	forelimb digit size	females	0.0 %	1.0
SHIRPA	forelimb digit size	males	0.0 %	1.0
SHIRPA	forelimb digit size	both	0.0 %	1.0
SHIRPA	forelimb footpads	females	0.0 %	1.0
SHIRPA	forelimb footpads	males	0.0 %	1.0
SHIRPA	forelimb footpads	both	0.0 %	1.0
SHIRPA	forelimb nail length	females	0.0 %	1.0
SHIRPA	forelimb nail length	males	0.0 %	1.0
SHIRPA	forelimb nail length	both	0.0 %	1.0
SHIRPA	forelimb nail number	females	0.0 %	1.0
SHIRPA	forelimb nail number	males	0.0 %	1.0
SHIRPA	forelimb nail number	both	0.0 %	1.0
SHIRPA	forelimb nail position	females	0.0 %	1.0
SHIRPA	forelimb nail position	males	0.0 %	1.0
SHIRPA	forelimb nail position	both	0.0 %	1.0
SHIRPA	forelimb nail shape	females	0.0 %	1.0
SHIRPA	forelimb nail shape	males	0.0 %	1.0
SHIRPA	forelimb nail shape	both	0.0 %	1.0
SHIRPA	forelimbs position	females	0.0 %	1.0
SHIRPA	forelimbs position	males	0.0 %	1.0
SHIRPA	forelimbs position	both	0.0 %	1.0
SHIRPA	forelimbs shape	females	0.0 %	1.0
SHIRPA	forelimbs shape	males	0.0 %	1.0
SHIRPA	forelimbs shape	both	0.0 %	1.0
SHIRPA	forelimbs size	females	0.0 %	1.0
SHIRPA	forelimbs size	males	0.0 %	1.0
SHIRPA	forelimbs size	both	0.0 %	1.0
SHIRPA	forepaw position	females	0.0 %	1.0
SHIRPA	forepaw position	males	0.0 %	1.0
SHIRPA	forepaw position	both	0.0 %	1.0
SHIRPA	forepaw shape	females	0.0 %	1.0
SHIRPA	forepaw shape	males	0.0 %	1.0
SHIRPA	forepaw shape	both	0.0 %	1.0
SHIRPA	forepaw size	females	0.0 %	1.0
SHIRPA	forepaw size	males	0.0 %	1.0
SHIRPA	forepaw size	both	0.0 %	1.0
SHIRPA	gait (fluidity)	females	0.0 %	1.0
SHIRPA	gait (fluidity)	males	0.0 %	1.00
SHIRPA	gait (fluidity)	both	0.0 %	1.0
SHIRPA	genitalia morphology	females	0.0 %	1.0
SHIRPA	genitalia morphology	males	0.0 %	1.0
SHIRPA	genitalia morphology	both	0.0 %	1.00
SHIRPA	genitalia presence	females	0.0 %	1.0
SHIRPA	genitalia presence	males	0.0 %	1.0
SHIRPA	genitalia presence	both	0.0 %	1.0
SHIRPA	genitalia size	females	0.0 %	1.0
SHIRPA	genitalia size	males	0.0 %	1.0
SHIRPA	genitalia size	both	0.0 %	1.00
SHIRPA	head bobbing	females	0.0 %	1.0
SHIRPA	head bobbing	males	0.0 %	1.0
SHIRPA	head bobbing	both	0.0 %	1.0
SHIRPA	head morphology	females	0.0 %	1.0
SHIRPA	head morphology	males	0.0 %	1.00
SHIRPA	head morphology	both	0.0 %	1.0
SHIRPA	head size	females	0.0 %	1.0
SHIRPA	head size	males	0.0 %	1.0
SHIRPA	head size	both	0.0 %	1.0
SHIRPA	hindlimb digit number	females	1.0 %	1.0
SHIRPA	hindlimb digit number	males	0.0 %	1.0
SHIRPA	hindlimb digit number	both	0.0 %	1.0
SHIRPA	hindlimb digit position	females	0.0 %	1.0
SHIRPA	hindlimb digit position	males	0.0 %	1.0
SHIRPA	hindlimb digit position	both	0.0 %	1.0
SHIRPA	hindlimb digit shape	females	0.0 %	1.0
SHIRPA	hindlimb digit shape	males	0.0 %	1.0
SHIRPA	hindlimb digit shape	both	0.0 %	1.00
SHIRPA	hindlimb digit size	females	0.0 %	1.0
SHIRPA	hindlimb digit size	males	0.0 %	1.0
SHIRPA	hindlimb digit size	both	0.0 %	1.00
SHIRPA	hindlimb nail length	females	0.0 %	1.0
SHIRPA	hindlimb nail length	males	0.0 %	1.0
SHIRPA	hindlimb nail length	both	0.0 %	1.0
SHIRPA	hindlimb nail number	females	0.0 %	1.0
SHIRPA	hindlimb nail number	males	1.0 %	1.0
SHIRPA	hindlimb nail number	both	0.0 %	1.0
SHIRPA	hindlimb nail position	females	0.0 %	1.0
SHIRPA	hindlimb nail position	males	0.0 %	1.0
SHIRPA	hindlimb nail position	both	0.0 %	1.0
SHIRPA	hindlimb nail shape	females	0.0 %	1.0
SHIRPA	hindlimb nail shape	males	0.0 %	1.0
SHIRPA	hindlimb nail shape	both	0.0 %	1.0
SHIRPA	hindlimbs footpads	females	0.0 %	1.0
SHIRPA	hindlimbs footpads	males	0.0 %	1.0
SHIRPA	hindlimbs footpads	both	0.0 %	1.0
SHIRPA	hindlimbs position	females	0.0 %	1.0
SHIRPA	hindlimbs position	males	0.0 %	1.0
SHIRPA	hindlimbs position	both	0.0 %	1.0
SHIRPA	hindlimbs shape	females	0.0 %	1.0
SHIRPA	hindlimbs shape	males	0.0 %	1.0
SHIRPA	hindlimbs shape	both	0.0 %	1.0
SHIRPA	hindlimbs size	females	0.0 %	1.0
SHIRPA	hindlimbs size	males	0.0 %	1.0
SHIRPA	hindlimbs size	both	0.0 %	1.0
SHIRPA	hindpaw position	females	0.0 %	1.0
SHIRPA	hindpaw position	males	0.0 %	1.0
SHIRPA	hindpaw position	both	0.0 %	1.0
SHIRPA	hindpaw shape	females	0.0 %	1.0
SHIRPA	hindpaw shape	males	0.0 %	1.0
SHIRPA	hindpaw shape	both	0.0 %	1.0
SHIRPA	hindpaw size	females	0.0 %	1.0
SHIRPA	hindpaw size	males	0.0 %	1.0
SHIRPA	hindpaw size	both	0.0 %	1.0
SHIRPA	limb grasp	females	9.0 %	1.0
SHIRPA	limb grasp	males	6.0 %	1.0
SHIRPA	limb grasp	both	7.0 %	0.620
SHIRPA	lower lip morphology	females	0.0 %	1.0
SHIRPA	lower lip morphology	males	0.0 %	1.0
SHIRPA	lower lip morphology	both	0.0 %	1.0
SHIRPA	lower teeth appearance	females	0.0 %	1.0
SHIRPA	lower teeth appearance	males	0.0 %	1.00
SHIRPA	lower teeth appearance	both	0.0 %	1.0
SHIRPA	mouth morphology	females	0.0 %	1.0
SHIRPA	mouth morphology	males	0.0 %	1.00
SHIRPA	mouth morphology	both	0.0 %	1.0
SHIRPA	salivation	females	0.0 %	1.0
SHIRPA	salivation	males	0.0 %	1.0
SHIRPA	salivation	both	0.0 %	1.0
SHIRPA	skin color back paws	females	0.0 %	1.0
SHIRPA	skin color back paws	males	0.0 %	1.0
SHIRPA	skin color back paws	both	0.0 %	1.0
SHIRPA	skin color ear	females	0.0 %	1.0
SHIRPA	skin color ear	males	0.0 %	1.0
SHIRPA	skin color ear	both	0.0 %	1.0
SHIRPA	skin color front paws	females	0.0 %	1.0
SHIRPA	skin color front paws	males	0.0 %	1.0
SHIRPA	skin color front paws	both	0.0 %	1.0
SHIRPA	skin color snout	females	0.0 %	1.0
SHIRPA	skin color snout	males	0.0 %	1.0
SHIRPA	skin color snout	both	0.0 %	1.0
SHIRPA	skin color tail	females	0.0 %	1.0
SHIRPA	skin color tail	males	0.0 %	1.0
SHIRPA	skin color tail	both	0.0 %	1.0
SHIRPA	skin color whole body	females	0.0 %	1.0
SHIRPA	skin color whole body	males	0.0 %	1.0
SHIRPA	skin color whole body	both	0.0 %	1.0
SHIRPA	skin texture back paw	females	0.0 %	1.0
SHIRPA	skin texture back paw	males	0.0 %	1.0
SHIRPA	skin texture back paw	both	0.0 %	1.0
SHIRPA	skin texture ear	females	0.0 %	1.0
SHIRPA	skin texture ear	males	0.0 %	1.0
SHIRPA	skin texture ear	both	0.0 %	1.0
SHIRPA	skin texture front paws	females	0.0 %	1.0
SHIRPA	skin texture front paws	males	0.0 %	1.0
SHIRPA	skin texture front paws	both	0.0 %	1.0
SHIRPA	skin texture snout	females	0.0 %	1.0
SHIRPA	skin texture snout	males	0.0 %	1.0
SHIRPA	skin texture snout	both	0.0 %	1.0
SHIRPA	skin texture tail	females	0.0 %	1.0
SHIRPA	skin texture tail	males	0.0 %	1.0
SHIRPA	skin texture tail	both	0.0 %	1.0
SHIRPA	skin texture whole body	females	0.0 %	1.0
SHIRPA	skin texture whole body	males	0.0 %	1.00
SHIRPA	skin texture whole body	both	0.0 %	1.00
SHIRPA	snout size	females	0.0 %	1.0
SHIRPA	snout size	males	1.0 %	1.0
SHIRPA	snout size	both	0.0 %	1.0
SHIRPA	startle response	females	0.0 %	1.0
SHIRPA	startle response	males	0.0 %	1.00
SHIRPA	startle response	both	0.0 %	1.0
SHIRPA	tail curvature	females	0.0 %	1.00
SHIRPA	tail curvature	males	0.0 %	1.0
SHIRPA	tail curvature	both	0.0 %	1.00
SHIRPA	tail elevation	females	1.0 %	1.0
SHIRPA	tail elevation	males	2.0 %	1.0
SHIRPA	tail elevation	both	1.0 %	1.0
SHIRPA	tail length	females	0.0 %	1.0
SHIRPA	tail length	males	0.0 %	1.0
SHIRPA	tail length	both	0.0 %	1.0
SHIRPA	tail morphology	females	0.0 %	1.0
SHIRPA	tail morphology	males	0.0 %	1.0
SHIRPA	tail morphology	both	0.0 %	1.00
SHIRPA	tail presence	females	0.0 %	1.0
SHIRPA	tail presence	males	0.0 %	1.0
SHIRPA	tail presence	both	0.0 %	1.0
SHIRPA	tail shape	females	0.0 %	1.0
SHIRPA	tail shape	males	0.0 %	1.0
SHIRPA	tail shape	both	0.0 %	1.0
SHIRPA	tail thickness	females	0.0 %	1.0
SHIRPA	tail thickness	males	0.0 %	1.0
SHIRPA	tail thickness	both	0.0 %	1.0
SHIRPA	teeth presence	females	0.0 %	1.0
SHIRPA	teeth presence	males	0.0 %	1.00
SHIRPA	teeth presence	both	0.0 %	1.0
SHIRPA	transfer arousal	females	1.0 %	1.0
SHIRPA	transfer arousal	males	2.0 %	1.00
SHIRPA	transfer arousal	both	1.0 %	1.0
SHIRPA	tremor	females	0.0 %	1.0
SHIRPA	tremor	males	0.0 %	1.0
SHIRPA	tremor	both	0.0 %	1.00
SHIRPA	trunk curl	females	0.0 %	1.0
SHIRPA	trunk curl	males	0.0 %	1.0
SHIRPA	trunk curl	both	0.0 %	1.00
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	females	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	males	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	both	0.0 %	1.0
SHIRPA	upper lip morphology	females	0.0 %	1.0
SHIRPA	upper lip morphology	males	0.0 %	1.0
SHIRPA	upper lip morphology	both	0.0 %	1.0
SHIRPA	upper teeth appearance	females	0.0 %	1.0
SHIRPA	upper teeth appearance	males	0.0 %	1.0
SHIRPA	upper teeth appearance	both	0.0 %	1.0
SHIRPA	vibrissae appearance	females	2.0 %	1.0
SHIRPA	vibrissae appearance	males	1.0 %	1.0
SHIRPA	vibrissae appearance	both	1.0 %	1.0
SHIRPA	vibrissae presence	females	2.0 %	1.00
SHIRPA	vibrissae presence	males	1.0 %	1.0
SHIRPA	vibrissae presence	both	2.0 %	1.0
SHIRPA	vocalization	females	2.0 %	1.0
SHIRPA	vocalization	males	2.0 %	1.0
SHIRPA	vocalization	both	2.0 %	1.0

GENOTYPE CORRELATION PLOT

Correlate Chmp1b^em1(IMPC)J/Mmjax -/- with genotype: