MPD: JaxKOMP-EAP genotype: Zbtb9<sup>em1(IMPC)J</sup>/Mmjax -/-

JaxKOMP-EAP effect sizes: Zbtb9^em1(IMPC)J/Mmjax -/- Gene Zbtb9

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	-3.3551	2.5439	undefined	undefined	0.203
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	1.4958	3.3561	undefined	undefined	0.661
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	-6.0471	5.5765	undefined	undefined	0.293
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	-0.50025	3.7417	undefined	undefined	0.895
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	-1.7262	3.0554	undefined	undefined	0.579
body composition	body length	-0.0010491	0.069075	undefined	undefined	0.988
body composition	body weight (at time of DXA)	-2.1893	0.45321	undefined	undefined	0.0000267
body composition	bone area, whole body scan, head excluded	-0.14205	0.24079	undefined	undefined	0.559
body composition	bone mineral content of whole body scan, head excluded	-0.0028464	0.018343	undefined	undefined	0.878
body composition	bone mineral content to body weight ratio	0.00060029	0.00064616	undefined	undefined	0.359
body composition	bone mineral density of whole body scan, head excluded	0.00044889	0.00076935	undefined	undefined	0.563
body composition	fat tissue mass of whole body scan, head excluded	-0.17494	0.48118	undefined	undefined	0.718
body composition	fat tissue mass to body weight ratio	-0.0013933	0.016383	undefined	undefined	0.933
body composition	lean tissue mass of whole body scan, head excluded	0.0056098	0.40955	undefined	undefined	0.989
body composition	lean tissue mass to body weight ratio	0.0030142	0.014441	undefined	undefined	0.836
body composition	percent fat, whole body scan, head excluded	-0.15570	1.5224	undefined	undefined	0.919
body composition	ratio of soft-tissue attenuation coefficients	0.00017985	0.0016863	undefined	undefined	0.916
body composition	tissue area	-0.30132	0.23572	undefined	undefined	0.210
body composition	total tissue mass, whole body scan, head excluded	-0.39097	0.30312	undefined	undefined	0.206
clinical blood chemistry	alanine transaminase (plasma ALT)	-19.210	16.200	undefined	undefined	0.243
clinical blood chemistry	albumin (plasma Alb)	-0.022278	0.50785	undefined	undefined	0.965
clinical blood chemistry	alkaline phosphatase (plasma ALP)	-1.4187	2.9442	undefined	undefined	0.633
clinical blood chemistry	aspartate transaminase (plasma AST)	-38.072	24.540	undefined	undefined	0.129
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	-0.18322	0.16970	undefined	undefined	0.287
clinical blood chemistry	blood urea nitrogen (BUN)	-2.8444	1.1627	undefined	undefined	0.0193
clinical blood chemistry	calcium (plasma Ca)	-0.021905	0.083824	undefined	undefined	0.795
clinical blood chemistry	creatinine (plasma)	-0.025159	0.029686	undefined	undefined	0.402
clinical blood chemistry	glucose (plasma GLU, no fast)	-4.8352	9.3322	undefined	undefined	0.607
clinical blood chemistry	HDL cholesterol (plasma HDL)	1.5684	2.8488	undefined	undefined	0.585
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	0.0026201	0.010322	undefined	undefined	0.801
clinical blood chemistry	phosphorus (plasma phosphate)	-0.80694	0.43919	undefined	undefined	0.0740
clinical blood chemistry	total bilirubin (plasma TBIL)	-0.019738	0.0099626	undefined	undefined	0.0548
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	1.4135	3.8946	undefined	undefined	0.719
clinical blood chemistry	total protein (plasma TP)	0.49004	0.67878	undefined	undefined	0.475
clinical blood chemistry	triglyceride (plasma TG, no fast)	-54.790	16.119	undefined	undefined	0.00160
glucose tolerance test	amount glucose injected	0.16803	1.6983	undefined	undefined	0.922
glucose tolerance test	plasma glucose, 0min	8.3797	3.7693	undefined	undefined	0.0309
glucose tolerance test	plasma glucose, 15min	40.921	13.323	undefined	undefined	0.00350
glucose tolerance test	plasma glucose, 30min	23.937	13.230	undefined	undefined	0.0767
glucose tolerance test	plasma glucose, 60min	8.8102	9.9302	undefined	undefined	0.379
glucose tolerance test	plasma glucose, 120min	4.6251	5.8564	undefined	undefined	0.434
grip strength	body weight (at time of grip strength test)	-1.2180	0.46022	undefined	undefined	0.0130
grip strength	forelimb and hindlimb grip strength (mean of trials), average	9.8240	5.5973	undefined	undefined	0.0902
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	0.35569	0.24812	undefined	undefined	0.163
grip strength	forelimb and hindlimb grip strength by trial, trial1	11.373	6.2072	undefined	undefined	0.0776
grip strength	forelimb and hindlimb grip strength by trial, trial2	5.8181	5.8419	undefined	undefined	0.328
grip strength	forelimb and hindlimb grip strength by trial, trial3	9.3679	6.1193	undefined	undefined	0.137
grip strength	forelimb grip strength (mean of trials), average	-2.8277	2.9522	undefined	undefined	0.346
grip strength	forelimb grip strength (mean of trials), average normalized to bw	-0.092751	0.16723	undefined	undefined	0.584
grip strength	forelimb grip strength by trial, trial1	-2.6583	3.6697	undefined	undefined	0.475
grip strength	forelimb grip strength by trial, trial2	-1.8935	3.2478	undefined	undefined	0.564
grip strength	forelimb grip strength by trial, trial3	-5.6312	3.8591	undefined	undefined	0.155
heart weight	heart weight, normalized to body weight	0.048559	0.14707	undefined	undefined	0.743
heart weight	heart weight, weight	-5.3000	4.3486	undefined	undefined	0.230
hematology	basophil differential (percent of total WBC)	-0.019369	0.044803	undefined	undefined	0.670
hematology	eosinophil differential (percent of total WBC)	-0.23962	0.34921	undefined	undefined	0.500
hematology	hematocrit (HCT)	-0.63914	0.87736	undefined	undefined	0.475
hematology	lymphocyte differential (percent of total WBC)	-13.690	4.9147	undefined	undefined	0.0114
hematology	mean corpuscular hemoglobin (CHr)	-0.043891	0.090222	undefined	undefined	0.632
hematology	mean platelet volume (MPV)	-0.017980	0.071636	undefined	undefined	0.804
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	0.38058	0.19072	undefined	undefined	0.0598
hematology	mean RBC corpuscular volume (MCV)	-0.82417	0.34353	undefined	undefined	0.0263
hematology	measured hemoglobin (mHGB)	-0.068034	0.26013	undefined	undefined	0.796
hematology	monocyte differential (percent of total WBC)	1.9758	0.70999	undefined	undefined	0.0115
hematology	neutrophil differential (percent of total WBC)	11.949	4.2890	undefined	undefined	0.0114
hematology	platelet count (PLT; units per volume x 10³)	-4.3679	55.321	undefined	undefined	0.938
hematology	RBC corpuscular distribution width (RDW)	0.23566	0.23905	undefined	undefined	0.336
hematology	red blood cell count (RBC; per volume x 10⁶)	0.017946	0.19228	undefined	undefined	0.927
hematology	reticulocyte count (Retic; units per volume x 10⁹)	-9.0096	15.467	undefined	undefined	0.567
hematology	reticulocyte differential (percent of total RBC)	-0.12333	0.13786	undefined	undefined	0.382
hematology	white blood cell count (WBC; units per volume x 10³)	-0.024092	0.71836	undefined	undefined	0.974
holeboard	number of hole pokes by individual hole number, 20 min test, 1	-0.31963	1.0540	undefined	undefined	0.763
holeboard	number of hole pokes by individual hole number, 20 min test, 2	-0.21896	0.62828	undefined	undefined	0.729
holeboard	number of hole pokes by individual hole number, 20 min test, 3	-0.29112	0.58272	undefined	undefined	0.620
holeboard	number of hole pokes by individual hole number, 20 min test, 4	-1.1891	0.95759	undefined	undefined	0.221
holeboard	number of hole pokes by individual hole number, 20 min test, 5	-0.38607	0.56415	undefined	undefined	0.497
holeboard	number of hole pokes by individual hole number, 20 min test, 6	-0.48840	0.37178	undefined	undefined	0.195
holeboard	number of hole pokes by individual hole number, 20 min test, 7	-0.43113	0.35591	undefined	undefined	0.232
holeboard	number of hole pokes by individual hole number, 20 min test, 8	0.18481	0.62502	undefined	undefined	0.769
holeboard	number of hole pokes by individual hole number, 20 min test, 9	-0.48071	0.52130	undefined	undefined	0.361
holeboard	number of hole pokes by individual hole number, 20 min test, 10	-0.32046	0.37796	undefined	undefined	0.401
holeboard	number of hole pokes by individual hole number, 20 min test, 11	-0.11362	0.39712	undefined	undefined	0.776
holeboard	number of hole pokes by individual hole number, 20 min test, 12	-0.55031	0.61212	undefined	undefined	0.373
holeboard	number of hole pokes by individual hole number, 20 min test, 13	-0.95393	1.0809	undefined	undefined	0.382
holeboard	number of hole pokes by individual hole number, 20 min test, 14	-0.43806	0.63089	undefined	undefined	0.491
holeboard	number of hole pokes by individual hole number, 20 min test, 15	-0.34485	0.75004	undefined	undefined	0.648
holeboard	number of hole pokes by individual hole number, 20 min test, 16	-1.1474	0.92068	undefined	undefined	0.219
holeboard	total number of hole pokes, 20 min test	-7.7530	5.6028	undefined	undefined	0.173
light / dark	latency to enter dark zone, 20 min test	-2.6263	41.530	undefined	undefined	0.950
light / dark	number of transitions between light and dark zones, 20 min test	-3.5518	5.9689	undefined	undefined	0.555
light / dark	percentage of total time in dark zone, 20 min test	6.6635	4.7839	undefined	undefined	0.170
light / dark	percentage of total time in light zone, 20 min test	-6.6635	4.7839	undefined	undefined	0.170
light / dark	time mobile in dark zone, 20 min test	5.4192	5.7516	undefined	undefined	0.351
light / dark	time mobile in light zone, 20 min test	-2.7445	4.3597	undefined	undefined	0.532
light / dark	time spent in dark zone, 20 min test	56.841	58.545	undefined	undefined	0.336
light / dark	time spent in light zone, 20 min test	-56.842	58.544	undefined	undefined	0.336
open field	average speed in center of arena, 20 min test	-0.80180	0.29349	undefined	undefined	0.00878
open field	average speed in periphery of arena, 20 min test	-0.46869	0.16037	undefined	undefined	0.00532
open field	distance traveled habituation ratio, 20 min test	6.1454	8.0409	undefined	undefined	0.448
open field	distance traveled in center of arena, 20 min test	-176.21	110.02	undefined	undefined	0.116
open field	distance traveled in periphery of arena, 20 min test	-411.33	142.14	undefined	undefined	0.00571
open field	distance traveled slope, 20 min test	4.9326	7.5133	undefined	undefined	0.515
open field	distance traveled, 20 min test, 1st 5min	-186.74	83.893	undefined	undefined	0.0307
open field	distance traveled, 20 min test, 2nd 5min	-130.69	49.842	undefined	undefined	0.0117
open field	distance traveled, 20 min test, 3rd 5min	-209.27	58.010	undefined	undefined	0.000747
open field	distance traveled, 20 min test, 4th 5min	-138.07	50.940	undefined	undefined	0.00929
open field	number of clockwise revolution episodes, 20 min test	-4.1997	1.4043	undefined	undefined	0.00442
open field	number of counter-clockwise revolution episodes, 20 min test	-2.7141	1.4944	undefined	undefined	0.0756
open field	number of rears in 5 min bins, 20 min test, 1st 5min	-9.5246	2.5686	undefined	undefined	0.000541
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	-8.0635	4.3100	undefined	undefined	0.0676
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	-11.689	3.1306	undefined	undefined	0.000500
open field	number of rears in 5 min bins, 20 min test, 4th 5min	-6.5902	4.2097	undefined	undefined	0.124
open field	percentage of total time in center of arena, 20 min test	6.0463	3.1823	undefined	undefined	0.0634
open field	percentage of total time in center of arena, slope, 20 min test	-2.5428	1.9638	undefined	undefined	0.202
open field	percentage of total time in center, habituation ratio, 20 min test	-2.8247	2.1268	undefined	undefined	0.190
open field	percentage of total time in corners of arena, 20 min test	-4.5547	2.3364	undefined	undefined	0.0571
open field	percentage of total time in corners, habituation ratio, 20 min test	0.58682	1.7841	undefined	undefined	0.744
open field	percentage of total time in corners, slope, 20 min test	0.19737	1.7387	undefined	undefined	0.910
open field	permanence time in center of arena, 20 min test	72.565	38.186	undefined	undefined	0.0634
open field	permanence time in corners of arena, 20 min test	-54.663	28.036	undefined	undefined	0.0571
open field	permanence time in periphery of arena, 20 min test	-72.566	38.186	undefined	undefined	0.0634
open field	total distance traveled, 20 min test	-585.37	210.63	undefined	undefined	0.00776
open field	total number of rears, 20 min test	-33.716	13.104	undefined	undefined	0.0133
open field	whole arena average speed, 20 min test	-0.48824	0.17559	undefined	undefined	0.00773
open field	whole arena resting time, 20 min test	101.38	21.527	undefined	undefined	0.0000215
open field	whole arena time spent mobile, 20 min test	-10.153	4.8951	undefined	undefined	0.0436
open field	whole arena time spent vertical, 20 min test	-12.732	8.5732	undefined	undefined	0.144
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	-1.9523	1.8664	undefined	undefined	0.304
startle / PPI	average baseline movement during background noise	-3.1433	1.1608	undefined	undefined	0.00941
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	-0.068174	0.059187	undefined	undefined	0.255
startle / PPI	average of each corrected percent pre-pulse inhibition value	-0.069844	0.055356	undefined	undefined	0.213
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-1.4791	5.4023	undefined	undefined	0.785
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-4.0574	6.2590	undefined	undefined	0.520
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-7.6950	5.6031	undefined	undefined	0.176
startle / PPI	average startle response to full pulse (120 dB)	101.04	42.704	undefined	undefined	0.0222
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	109.75	42.035	undefined	undefined	0.0121
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	93.301	42.164	undefined	undefined	0.0319
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	91.560	39.439	undefined	undefined	0.0247
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	-2.8657	1.0209	undefined	undefined	0.00726
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	-1.7160	1.8272	undefined	undefined	0.352
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	-2.7133	2.1542	undefined	undefined	0.214
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.015823	0.062926	undefined	undefined	0.803
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.065928	0.071545	undefined	undefined	0.362
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-0.061842	0.066424	undefined	undefined	0.357
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	104.06	42.580	undefined	undefined	0.0183
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	113.16	42.257	undefined	undefined	0.0102
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	95.459	42.339	undefined	undefined	0.0290
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	93.852	39.646	undefined	undefined	0.0222
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.0075959	0.068815	undefined	undefined	0.913
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.073707	0.078209	undefined	undefined	0.351
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-0.062639	0.065533	undefined	undefined	0.344
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	379.42	154.41	undefined	undefined	0.0177
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	401.81	150.34	undefined	undefined	0.0103
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	299.20	138.14	undefined	undefined	0.0354
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	308.38	131.54	undefined	undefined	0.0233
startle / PPI	maximum baseline movement during background noise	-6.7962	2.5589	undefined	undefined	0.0108
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.87963	5.9050	undefined	undefined	0.882
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-5.7834	7.0871	undefined	undefined	0.419
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-7.6892	6.1647	undefined	undefined	0.219
startle / PPI	maximum startle response to full pulse (120 dB)	373.53	154.54	undefined	undefined	0.0196
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	394.96	149.45	undefined	undefined	0.0111
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	297.58	137.65	undefined	undefined	0.0358
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	304.62	130.89	undefined	undefined	0.0243
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	-5.7489	2.3566	undefined	undefined	0.0185
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	-1.7806	4.1155	undefined	undefined	0.667
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	-4.6661	4.7841	undefined	undefined	0.334

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Sex	Trait Effect	P-value
eye morphology	anterior chamber depth	females	1.0 %	1.0
eye morphology	anterior chamber depth	males	0.0 %	1.0
eye morphology	anterior chamber depth	both	1.0 %	1.0
eye morphology	bulging eye	females	1.0 %	1.00
eye morphology	bulging eye	males	0.0 %	1.0
eye morphology	bulging eye	both	1.0 %	1.0
eye morphology	cornea	females	4.0 %	1.0
eye morphology	cornea	males	2.0 %	1.0
eye morphology	cornea	both	3.0 %	1.00
eye morphology	cornea opacity	females	5.0 %	1.0
eye morphology	cornea opacity	males	1.0 %	1.0
eye morphology	cornea opacity	both	3.0 %	1.0
eye morphology	cornea vascularization	females	3.0 %	1.0
eye morphology	cornea vascularization	males	1.0 %	1.0
eye morphology	cornea vascularization	both	2.0 %	1.0
eye morphology	corneal deposits	females	2.0 %	1.0
eye morphology	corneal deposits	males	1.0 %	1.0
eye morphology	corneal deposits	both	1.0 %	1.00
eye morphology	corneal mineralization	females	2.0 %	1.0
eye morphology	corneal mineralization	males	1.0 %	1.0
eye morphology	corneal mineralization	both	1.0 %	1.00
eye morphology	corneal scleralization	females	3.0 %	1.0
eye morphology	corneal scleralization	males	1.0 %	1.0
eye morphology	corneal scleralization	both	2.0 %	1.0
eye morphology	corneal ulcer	females	1.0 %	1.0
eye morphology	corneal ulcer	males	1.0 %	1.0
eye morphology	corneal ulcer	both	1.0 %	1.00
eye morphology	eye closure	females	1.0 %	1.0
eye morphology	eye closure	males	0.0 %	1.0
eye morphology	eye closure	both	1.0 %	1.00
eye morphology	eye hemorrhage or blood presence	females	2.0 %	1.0
eye morphology	eye hemorrhage or blood presence	males	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	both	1.0 %	1.0
eye morphology	eyelid morphology	females	1.0 %	1.0
eye morphology	eyelid morphology	males	0.0 %	1.0
eye morphology	eyelid morphology	both	1.0 %	1.00
eye morphology	eyes (present, absent)	females	1.0 %	1.0
eye morphology	eyes (present, absent)	males	0.0 %	1.0
eye morphology	eyes (present, absent)	both	0.0 %	1.00
eye morphology	fusion between cornea and lens	females	4.0 %	1.0
eye morphology	fusion between cornea and lens	males	2.0 %	1.0
eye morphology	fusion between cornea and lens	both	3.0 %	1.0
eye morphology	iris pigmentation	females	2.0 %	1.0
eye morphology	iris pigmentation	males	1.0 %	1.0
eye morphology	iris pigmentation	both	2.0 %	1.0
eye morphology	iris transillumination	females	2.0 %	1.0
eye morphology	iris transillumination	males	1.0 %	1.0
eye morphology	iris transillumination	both	1.0 %	1.00
eye morphology	irispupil	females	4.0 %	1.0
eye morphology	irispupil	males	3.0 %	1.0
eye morphology	irispupil	both	3.0 %	1.0
eye morphology	lacrimation	females	3.0 %	1.0
eye morphology	lacrimation	males	2.0 %	1.0
eye morphology	lacrimation	both	3.0 %	1.00
eye morphology	lens	females	10.0 %	1.0
eye morphology	lens	males	8.0 %	1.0
eye morphology	lens	both	9.0 %	1.00
eye morphology	lens opacity	females	22.0 %	0.315
eye morphology	lens opacity	males	6.0 %	1.0
eye morphology	lens opacity	both	6.0 %	0.597
eye morphology	narrow eye opening	females	2.0 %	1.0
eye morphology	narrow eye opening	males	1.0 %	1.0
eye morphology	narrow eye opening	both	1.0 %	1.00
eye morphology	optic disc	females	4.0 %	1.0
eye morphology	optic disc	males	2.0 %	1.0
eye morphology	optic disc	both	3.0 %	1.00
eye morphology	persistence of hyaloid vascular system	females	14.0 %	1.0
eye morphology	persistence of hyaloid vascular system	males	5.0 %	1.0
eye morphology	persistence of hyaloid vascular system	both	9.0 %	1.00
eye morphology	pupil dilation	females	2.0 %	1.0
eye morphology	pupil dilation	males	1.0 %	1.0
eye morphology	pupil dilation	both	2.0 %	1.00
eye morphology	pupil light response	females	2.0 %	1.0
eye morphology	pupil light response	males	1.0 %	1.0
eye morphology	pupil light response	both	2.0 %	1.0
eye morphology	pupil position	females	4.0 %	1.0
eye morphology	pupil position	males	3.0 %	1.0
eye morphology	pupil position	both	4.0 %	1.0
eye morphology	pupil shape	females	3.0 %	1.0
eye morphology	pupil shape	males	2.0 %	1.0
eye morphology	pupil shape	both	3.0 %	1.0
eye morphology	retina	females	10.0 %	1.0
eye morphology	retina	males	7.0 %	0.610
eye morphology	retina	both	4.0 %	0.693
eye morphology	retinal blood vessels	females	4.0 %	1.0
eye morphology	retinal blood vessels	males	2.0 %	1.0
eye morphology	retinal blood vessels	both	3.0 %	1.00
eye morphology	retinal blood vessels pattern	females	5.0 %	1.0
eye morphology	retinal blood vessels pattern	males	2.0 %	1.0
eye morphology	retinal blood vessels pattern	both	4.0 %	1.00
eye morphology	retinal blood vessels structure	females	4.0 %	1.0
eye morphology	retinal blood vessels structure	males	2.0 %	1.0
eye morphology	retinal blood vessels structure	both	3.0 %	1.0
eye morphology	retinal pigmentation	females	12.0 %	1.0
eye morphology	retinal pigmentation	males	14.0 %	1.0
eye morphology	retinal pigmentation	both	13.0 %	1.00
eye morphology	retinal structure	females	4.0 %	1.0
eye morphology	retinal structure	males	2.0 %	1.0
eye morphology	retinal structure	both	3.0 %	1.00
eye morphology	synechia	females	4.0 %	1.0
eye morphology	synechia	males	2.0 %	1.0
eye morphology	synechia	both	3.0 %	1.00
eye morphology	vitreous	females	4.0 %	1.0
eye morphology	vitreous	males	2.0 %	1.0
eye morphology	vitreous	both	3.0 %	1.0
SHIRPA	activity body position	females	1.0 %	1.0
SHIRPA	activity body position	males	2.0 %	1.0
SHIRPA	activity body position	both	1.0 %	1.00
SHIRPA	aggression	females	0.0 %	1.00
SHIRPA	aggression	males	1.0 %	1.0
SHIRPA	aggression	both	1.0 %	1.0
SHIRPA	body length	females	0.0 %	1.00
SHIRPA	body length	males	0.0 %	1.0
SHIRPA	body length	both	0.0 %	1.00
SHIRPA	body position	females	0.0 %	1.00
SHIRPA	body position	males	1.0 %	1.0
SHIRPA	body position	both	0.0 %	1.0
SHIRPA	body thickness	females	1.0 %	1.00
SHIRPA	body thickness	males	0.0 %	1.0
SHIRPA	body thickness	both	0.0 %	1.0
SHIRPA	coat color abdomen	females	3.0 %	1.00
SHIRPA	coat color abdomen	males	4.0 %	1.00
SHIRPA	coat color abdomen	both	4.0 %	1.0
SHIRPA	coat color back	females	0.0 %	1.00
SHIRPA	coat color back	males	0.0 %	1.0
SHIRPA	coat color back	both	0.0 %	1.0
SHIRPA	coat color head	females	0.0 %	1.00
SHIRPA	coat color head	males	0.0 %	1.0
SHIRPA	coat color head	both	0.0 %	1.0
SHIRPA	coat color pattern abdomen	females	1.0 %	1.00
SHIRPA	coat color pattern abdomen	males	1.0 %	1.0
SHIRPA	coat color pattern abdomen	both	1.0 %	1.0
SHIRPA	coat color pattern back	females	0.0 %	1.00
SHIRPA	coat color pattern back	males	0.0 %	1.0
SHIRPA	coat color pattern back	both	0.0 %	1.0
SHIRPA	coat color pattern head	females	0.0 %	1.00
SHIRPA	coat color pattern head	males	0.0 %	1.00
SHIRPA	coat color pattern head	both	0.0 %	1.00
SHIRPA	coat hair abdomen texture appearance	females	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	males	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	both	2.0 %	1.0
SHIRPA	coat hair back texture appearance	females	0.0 %	1.00
SHIRPA	coat hair back texture appearance	males	0.0 %	1.0
SHIRPA	coat hair back texture appearance	both	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	females	0.0 %	1.00
SHIRPA	coat hair distribution abdomen	males	1.0 %	1.0
SHIRPA	coat hair distribution abdomen	both	1.0 %	1.0
SHIRPA	coat hair distribution back	females	0.0 %	1.00
SHIRPA	coat hair distribution back	males	0.0 %	1.0
SHIRPA	coat hair distribution back	both	0.0 %	1.00
SHIRPA	coat hair distribution head	females	1.0 %	1.00
SHIRPA	coat hair distribution head	males	1.0 %	1.0
SHIRPA	coat hair distribution head	both	1.0 %	1.0
SHIRPA	coat hair head texture appearance	females	0.0 %	1.00
SHIRPA	coat hair head texture appearance	males	0.0 %	1.0
SHIRPA	coat hair head texture appearance	both	0.0 %	1.0
SHIRPA	contact righting	females	5.0 %	1.0
SHIRPA	contact righting	males	5.0 %	1.00
SHIRPA	contact righting	both	5.0 %	1.0
SHIRPA	ear morphology	females	0.0 %	1.0
SHIRPA	ear morphology	males	0.0 %	1.0
SHIRPA	ear morphology	both	0.0 %	1.0
SHIRPA	fat distribution	females	0.0 %	1.00
SHIRPA	fat distribution	males	0.0 %	1.0
SHIRPA	fat distribution	both	0.0 %	1.0
SHIRPA	forelimb digit number	females	0.0 %	1.00
SHIRPA	forelimb digit number	males	0.0 %	1.0
SHIRPA	forelimb digit number	both	0.0 %	1.0
SHIRPA	forelimb digit position	females	0.0 %	1.0
SHIRPA	forelimb digit position	males	0.0 %	1.0
SHIRPA	forelimb digit position	both	0.0 %	1.0
SHIRPA	forelimb digit shape	females	0.0 %	1.0
SHIRPA	forelimb digit shape	males	0.0 %	1.0
SHIRPA	forelimb digit shape	both	0.0 %	1.0
SHIRPA	forelimb digit size	females	0.0 %	1.0
SHIRPA	forelimb digit size	males	0.0 %	1.0
SHIRPA	forelimb digit size	both	0.0 %	1.0
SHIRPA	forelimb footpads	females	0.0 %	1.00
SHIRPA	forelimb footpads	males	0.0 %	1.0
SHIRPA	forelimb footpads	both	0.0 %	1.0
SHIRPA	forelimb nail length	females	0.0 %	1.0
SHIRPA	forelimb nail length	males	0.0 %	1.0
SHIRPA	forelimb nail length	both	0.0 %	1.0
SHIRPA	forelimb nail number	females	0.0 %	1.0
SHIRPA	forelimb nail number	males	0.0 %	1.0
SHIRPA	forelimb nail number	both	0.0 %	1.0
SHIRPA	forelimb nail position	females	0.0 %	1.0
SHIRPA	forelimb nail position	males	0.0 %	1.0
SHIRPA	forelimb nail position	both	0.0 %	1.0
SHIRPA	forelimb nail shape	females	0.0 %	1.0
SHIRPA	forelimb nail shape	males	0.0 %	1.0
SHIRPA	forelimb nail shape	both	0.0 %	1.0
SHIRPA	forelimbs position	females	0.0 %	1.0
SHIRPA	forelimbs position	males	0.0 %	1.0
SHIRPA	forelimbs position	both	0.0 %	1.0
SHIRPA	forelimbs shape	females	0.0 %	1.0
SHIRPA	forelimbs shape	males	0.0 %	1.0
SHIRPA	forelimbs shape	both	0.0 %	1.0
SHIRPA	forelimbs size	females	0.0 %	1.00
SHIRPA	forelimbs size	males	0.0 %	1.00
SHIRPA	forelimbs size	both	0.0 %	1.0
SHIRPA	forepaw position	females	0.0 %	1.0
SHIRPA	forepaw position	males	0.0 %	1.0
SHIRPA	forepaw position	both	0.0 %	1.0
SHIRPA	forepaw shape	females	0.0 %	1.0
SHIRPA	forepaw shape	males	0.0 %	1.0
SHIRPA	forepaw shape	both	0.0 %	1.0
SHIRPA	forepaw size	females	0.0 %	1.0
SHIRPA	forepaw size	males	0.0 %	1.0
SHIRPA	forepaw size	both	0.0 %	1.0
SHIRPA	gait (fluidity)	females	0.0 %	1.0
SHIRPA	gait (fluidity)	males	0.0 %	1.0
SHIRPA	gait (fluidity)	both	0.0 %	1.0
SHIRPA	genitalia morphology	females	0.0 %	1.00
SHIRPA	genitalia morphology	males	0.0 %	1.0
SHIRPA	genitalia morphology	both	0.0 %	1.0
SHIRPA	genitalia presence	females	0.0 %	1.00
SHIRPA	genitalia presence	males	0.0 %	1.0
SHIRPA	genitalia presence	both	0.0 %	1.0
SHIRPA	genitalia size	females	0.0 %	1.0
SHIRPA	genitalia size	males	0.0 %	1.00
SHIRPA	genitalia size	both	0.0 %	1.0
SHIRPA	head bobbing	females	0.0 %	1.0
SHIRPA	head bobbing	males	0.0 %	1.0
SHIRPA	head bobbing	both	0.0 %	1.0
SHIRPA	head morphology	females	0.0 %	1.00
SHIRPA	head morphology	males	0.0 %	1.0
SHIRPA	head morphology	both	0.0 %	1.0
SHIRPA	head size	females	0.0 %	1.0
SHIRPA	head size	males	0.0 %	1.00
SHIRPA	head size	both	0.0 %	1.0
SHIRPA	hindlimb digit number	females	1.0 %	1.00
SHIRPA	hindlimb digit number	males	0.0 %	1.0
SHIRPA	hindlimb digit number	both	0.0 %	1.0
SHIRPA	hindlimb digit position	females	0.0 %	1.00
SHIRPA	hindlimb digit position	males	0.0 %	1.0
SHIRPA	hindlimb digit position	both	0.0 %	1.0
SHIRPA	hindlimb digit shape	females	0.0 %	1.00
SHIRPA	hindlimb digit shape	males	0.0 %	1.0
SHIRPA	hindlimb digit shape	both	0.0 %	1.00
SHIRPA	hindlimb digit size	females	0.0 %	1.00
SHIRPA	hindlimb digit size	males	0.0 %	1.00
SHIRPA	hindlimb digit size	both	0.0 %	1.0
SHIRPA	hindlimb nail length	females	0.0 %	1.0
SHIRPA	hindlimb nail length	males	0.0 %	1.00
SHIRPA	hindlimb nail length	both	0.0 %	1.0
SHIRPA	hindlimb nail number	females	0.0 %	1.0
SHIRPA	hindlimb nail number	males	1.0 %	1.00
SHIRPA	hindlimb nail number	both	0.0 %	1.0
SHIRPA	hindlimb nail position	females	0.0 %	1.0
SHIRPA	hindlimb nail position	males	0.0 %	1.0
SHIRPA	hindlimb nail position	both	0.0 %	1.0
SHIRPA	hindlimb nail shape	females	0.0 %	1.0
SHIRPA	hindlimb nail shape	males	0.0 %	1.0
SHIRPA	hindlimb nail shape	both	0.0 %	1.0
SHIRPA	hindlimbs footpads	females	0.0 %	1.00
SHIRPA	hindlimbs footpads	males	0.0 %	1.0
SHIRPA	hindlimbs footpads	both	0.0 %	1.0
SHIRPA	hindlimbs position	females	0.0 %	1.0
SHIRPA	hindlimbs position	males	0.0 %	1.0
SHIRPA	hindlimbs position	both	0.0 %	1.0
SHIRPA	hindlimbs shape	females	0.0 %	1.0
SHIRPA	hindlimbs shape	males	0.0 %	1.0
SHIRPA	hindlimbs shape	both	0.0 %	1.0
SHIRPA	hindlimbs size	females	0.0 %	1.0
SHIRPA	hindlimbs size	males	0.0 %	1.0
SHIRPA	hindlimbs size	both	0.0 %	1.0
SHIRPA	hindpaw position	females	0.0 %	1.0
SHIRPA	hindpaw position	males	0.0 %	1.0
SHIRPA	hindpaw position	both	0.0 %	1.0
SHIRPA	hindpaw shape	females	0.0 %	1.00
SHIRPA	hindpaw shape	males	0.0 %	1.0
SHIRPA	hindpaw shape	both	0.0 %	1.0
SHIRPA	hindpaw size	females	0.0 %	1.00
SHIRPA	hindpaw size	males	0.0 %	1.0
SHIRPA	hindpaw size	both	0.0 %	1.0
SHIRPA	limb grasp	females	9.0 %	1.00
SHIRPA	limb grasp	males	6.0 %	1.0
SHIRPA	limb grasp	both	7.0 %	1.0
SHIRPA	lower lip morphology	females	0.0 %	1.00
SHIRPA	lower lip morphology	males	0.0 %	1.0
SHIRPA	lower lip morphology	both	0.0 %	1.0
SHIRPA	lower teeth appearance	females	0.0 %	1.0
SHIRPA	lower teeth appearance	males	0.0 %	1.0
SHIRPA	lower teeth appearance	both	0.0 %	1.00
SHIRPA	mouth morphology	females	0.0 %	1.0
SHIRPA	mouth morphology	males	0.0 %	1.0
SHIRPA	mouth morphology	both	0.0 %	1.0
SHIRPA	salivation	females	0.0 %	1.0
SHIRPA	salivation	males	0.0 %	1.0
SHIRPA	salivation	both	0.0 %	1.0
SHIRPA	skin color back paws	females	0.0 %	1.0
SHIRPA	skin color back paws	males	0.0 %	1.0
SHIRPA	skin color back paws	both	0.0 %	1.0
SHIRPA	skin color ear	females	0.0 %	1.0
SHIRPA	skin color ear	males	0.0 %	1.0
SHIRPA	skin color ear	both	0.0 %	1.0
SHIRPA	skin color front paws	females	0.0 %	1.0
SHIRPA	skin color front paws	males	0.0 %	1.0
SHIRPA	skin color front paws	both	0.0 %	1.0
SHIRPA	skin color snout	females	0.0 %	1.0
SHIRPA	skin color snout	males	0.0 %	1.0
SHIRPA	skin color snout	both	0.0 %	1.0
SHIRPA	skin color tail	females	0.0 %	1.0
SHIRPA	skin color tail	males	0.0 %	1.0
SHIRPA	skin color tail	both	0.0 %	1.0
SHIRPA	skin color whole body	females	0.0 %	1.00
SHIRPA	skin color whole body	males	0.0 %	1.0
SHIRPA	skin color whole body	both	0.0 %	1.0
SHIRPA	skin texture back paw	females	0.0 %	1.0
SHIRPA	skin texture back paw	males	0.0 %	1.0
SHIRPA	skin texture back paw	both	0.0 %	1.0
SHIRPA	skin texture ear	females	0.0 %	1.0
SHIRPA	skin texture ear	males	0.0 %	1.0
SHIRPA	skin texture ear	both	0.0 %	1.0
SHIRPA	skin texture front paws	females	0.0 %	1.0
SHIRPA	skin texture front paws	males	0.0 %	1.0
SHIRPA	skin texture front paws	both	0.0 %	1.0
SHIRPA	skin texture snout	females	0.0 %	1.0
SHIRPA	skin texture snout	males	0.0 %	1.0
SHIRPA	skin texture snout	both	0.0 %	1.0
SHIRPA	skin texture tail	females	0.0 %	1.0
SHIRPA	skin texture tail	males	0.0 %	1.0
SHIRPA	skin texture tail	both	0.0 %	1.0
SHIRPA	skin texture whole body	females	0.0 %	1.0
SHIRPA	skin texture whole body	males	0.0 %	1.0
SHIRPA	skin texture whole body	both	0.0 %	1.0
SHIRPA	snout size	females	0.0 %	1.00
SHIRPA	snout size	males	1.0 %	1.0
SHIRPA	snout size	both	0.0 %	1.0
SHIRPA	startle response	females	0.0 %	1.0
SHIRPA	startle response	males	0.0 %	1.00
SHIRPA	startle response	both	0.0 %	1.0
SHIRPA	tail curvature	females	0.0 %	1.0
SHIRPA	tail curvature	males	0.0 %	1.0
SHIRPA	tail curvature	both	0.0 %	1.00
SHIRPA	tail elevation	females	1.0 %	1.00
SHIRPA	tail elevation	males	2.0 %	1.0
SHIRPA	tail elevation	both	1.0 %	1.0
SHIRPA	tail length	females	0.0 %	1.00
SHIRPA	tail length	males	0.0 %	1.00
SHIRPA	tail length	both	0.0 %	1.00
SHIRPA	tail morphology	females	0.0 %	1.00
SHIRPA	tail morphology	males	0.0 %	1.00
SHIRPA	tail morphology	both	0.0 %	1.0
SHIRPA	tail presence	females	0.0 %	1.0
SHIRPA	tail presence	males	0.0 %	1.0
SHIRPA	tail presence	both	0.0 %	1.0
SHIRPA	tail shape	females	0.0 %	1.00
SHIRPA	tail shape	males	0.0 %	1.0
SHIRPA	tail shape	both	0.0 %	1.00
SHIRPA	tail thickness	females	0.0 %	1.0
SHIRPA	tail thickness	males	0.0 %	1.0
SHIRPA	tail thickness	both	0.0 %	1.0
SHIRPA	teeth presence	females	0.0 %	1.00
SHIRPA	teeth presence	males	0.0 %	1.0
SHIRPA	teeth presence	both	0.0 %	1.00
SHIRPA	transfer arousal	females	1.0 %	1.0
SHIRPA	transfer arousal	males	2.0 %	1.0
SHIRPA	transfer arousal	both	1.0 %	1.0
SHIRPA	tremor	females	0.0 %	1.00
SHIRPA	tremor	males	0.0 %	1.0
SHIRPA	tremor	both	0.0 %	1.0
SHIRPA	trunk curl	females	0.0 %	1.00
SHIRPA	trunk curl	males	0.0 %	1.0
SHIRPA	trunk curl	both	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	females	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	males	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	both	0.0 %	1.0
SHIRPA	upper lip morphology	females	0.0 %	1.0
SHIRPA	upper lip morphology	males	0.0 %	1.0
SHIRPA	upper lip morphology	both	0.0 %	1.0
SHIRPA	upper teeth appearance	females	0.0 %	1.00
SHIRPA	upper teeth appearance	males	0.0 %	1.00
SHIRPA	upper teeth appearance	both	0.0 %	1.00
SHIRPA	vibrissae appearance	females	2.0 %	1.0
SHIRPA	vibrissae appearance	males	1.0 %	1.0
SHIRPA	vibrissae appearance	both	1.0 %	1.0
SHIRPA	vibrissae presence	females	2.0 %	1.0
SHIRPA	vibrissae presence	males	1.0 %	1.0
SHIRPA	vibrissae presence	both	2.0 %	1.0
SHIRPA	vocalization	females	2.0 %	1.00
SHIRPA	vocalization	males	2.0 %	1.0
SHIRPA	vocalization	both	2.0 %	1.0

GENOTYPE CORRELATION PLOT

Correlate Zbtb9^em1(IMPC)J/Mmjax -/- with genotype: