MPD: JaxKOMP-EAP genotype: Zdhhc22<sup>em1(IMPC)J</sup>/Mmjax -/-

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

In this plot, data points are the computed genotype effect size vs. C57BL/6NJ controls, for all measured numeric phenotypes in JaxKOMP-EAP

Dimensions Width: × Height: px

Plot Options Group by Procedure Standard Error Show Effect Sizes RankZ

Significance Threshold p-Value Threshold Adjusted Unadjusted

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Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value

ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	-1.1782	2.8710	-0.62118	0.914	0.709
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	-2.8606	3.1566	-0.63629	0.826	0.432
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	-5.3846	2.7860	-1.2300	0.505	0.149
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	2.1463	4.4521	0.23218	0.878	0.663
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	4.6756	9.3733	0.71193	0.863	0.652
body composition	body length	-0.045185	0.051951	-0.32352	0.744	0.476
body composition	body weight (at time of DXA)	0.87828	0.76842	0.79284	0.587	0.371
body composition	bone area, whole body scan, head excluded	-0.14455	0.26662	-0.38767	0.825	0.642
body composition	bone mineral content of whole body scan, head excluded	-0.011991	0.033602	-0.51627	0.896	0.755
body composition	bone mineral content to body weight ratio	-0.0010210	0.00083007	-1.0755	0.609	0.344
body composition	bone mineral density of whole body scan, head excluded	-0.00067268	0.0017797	-0.71757	0.878	0.742
body composition	fat tissue mass of whole body scan, head excluded	0.81508	0.94546	1.1704	0.708	0.479
body composition	fat tissue mass to body weight ratio	0.028938	0.028454	1.2149	0.647	0.416
body composition	lean tissue mass of whole body scan, head excluded	0.075536	0.87912	0.0040958	0.984	0.939
body composition	lean tissue mass to body weight ratio	-0.012246	0.033520	-0.72288	0.879	0.750
body composition	percent fat, whole body scan, head excluded	2.4063	2.5696	1.1179	0.676	0.448
body composition	ratio of soft-tissue attenuation coefficients	-0.0026490	0.0026412	-1.1014	0.653	0.422
body composition	tissue area	0.42377	0.16271	1.4114	0.383	0.121
body composition	total tissue mass, whole body scan, head excluded	0.85278	0.20071	1.3901	0.196	0.0512
glucose tolerance test	amount glucose injected	4.5734	2.5526	1.5076	0.406	0.0844
glucose tolerance test	plasma glucose, 0min	5.5874	4.9570	0.33566	0.487	0.269
glucose tolerance test	plasma glucose, 15min	7.6827	22.645	0.32551	0.904	0.737
glucose tolerance test	plasma glucose, 30min	25.991	32.282	0.88588	0.729	0.428
glucose tolerance test	plasma glucose, 60min	35.855	18.136	1.4550	0.282	0.0583
glucose tolerance test	plasma glucose, 120min	15.899	6.8770	0.93151	0.219	0.0284
grip strength	body weight (at time of grip strength test)	0.69649	0.40213	0.86796	0.227	0.0932
grip strength	forelimb and hindlimb grip strength (mean of trials), average	10.545	6.0027	1.0141	0.238	0.0888
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	0.26573	0.28662	0.57645	0.569	0.361
grip strength	forelimb and hindlimb grip strength by trial, trial1	9.9970	7.0079	0.93695	0.432	0.164
grip strength	forelimb and hindlimb grip strength by trial, trial2	8.6473	7.4185	0.78937	0.508	0.253
grip strength	forelimb and hindlimb grip strength by trial, trial3	9.9947	8.1870	0.88419	0.497	0.231
grip strength	forelimb grip strength (mean of trials), average	7.7785	3.2589	1.2607	0.132	0.0235
grip strength	forelimb grip strength (mean of trials), average normalized to bw	0.28218	0.15139	0.97596	0.261	0.0721
grip strength	forelimb grip strength by trial, trial1	3.3066	5.2683	0.64113	0.803	0.535
grip strength	forelimb grip strength by trial, trial2	10.207	4.7922	1.3208	0.245	0.0412
grip strength	forelimb grip strength by trial, trial3	10.415	4.7273	1.3243	0.216	0.0354
heart weight	heart weight, normalized to body weight	0.011697	0.099952	-0.41497	0.954	0.908
heart weight	heart weight, weight	0.44882	3.3974	-0.31526	0.942	0.896
holeboard	number of hole pokes by individual hole number, 20 min test, 1	1.9672	0.96498	1.6801	0.472	0.0501
holeboard	number of hole pokes by individual hole number, 20 min test, 2	0.30509	0.61787	0.59650	0.904	0.625
holeboard	number of hole pokes by individual hole number, 20 min test, 3	-0.21298	0.48284	-0.28134	0.928	0.662
holeboard	number of hole pokes by individual hole number, 20 min test, 4	0.87714	0.95780	0.93165	0.776	0.367
holeboard	number of hole pokes by individual hole number, 20 min test, 5	-0.29237	0.74787	-0.37036	0.939	0.699
holeboard	number of hole pokes by individual hole number, 20 min test, 6	-0.10229	0.47052	-0.27851	0.970	0.829
holeboard	number of hole pokes by individual hole number, 20 min test, 7	-0.050382	0.33337	-0.16555	0.991	0.881
holeboard	number of hole pokes by individual hole number, 20 min test, 8	0.53282	0.63400	1.0101	0.838	0.407
holeboard	number of hole pokes by individual hole number, 20 min test, 9	-0.19847	0.62312	-0.28417	0.954	0.752
holeboard	number of hole pokes by individual hole number, 20 min test, 10	-0.18702	0.43806	-0.45874	0.946	0.672
holeboard	number of hole pokes by individual hole number, 20 min test, 11	-0.58251	0.34711	-1.5382	0.673	0.103
holeboard	number of hole pokes by individual hole number, 20 min test, 12	0.87176	0.61855	1.3397	0.616	0.169
holeboard	number of hole pokes by individual hole number, 20 min test, 13	-0.40382	1.3538	-0.30492	0.937	0.767
holeboard	number of hole pokes by individual hole number, 20 min test, 14	-0.27328	0.80282	-0.33332	0.923	0.736
holeboard	number of hole pokes by individual hole number, 20 min test, 15	0.64122	0.95664	1.0804	0.852	0.508
holeboard	number of hole pokes by individual hole number, 20 min test, 16	1.6137	1.1102	1.3867	0.584	0.156
holeboard	total number of hole pokes, 20 min test	4.7092	6.8438	0.72733	0.732	0.497
open field	average speed in center of arena, 20 min test	0.18559	0.36699	0.24061	0.843	0.617
open field	average speed in periphery of arena, 20 min test	0.024685	0.12347	-0.42975	0.917	0.843
open field	distance traveled habituation ratio, 20 min test	-26.911	6.7769	-2.0575	0.0177	0.000396
open field	distance traveled in center of arena, 20 min test	-163.80	104.13	-1.3712	0.344	0.126
open field	distance traveled in periphery of arena, 20 min test	144.51	131.64	0.14755	0.522	0.281
open field	distance traveled slope, 20 min test	-26.536	6.5994	-2.0575	0.0146	0.000345
open field	distance traveled, 20 min test, 1st 5min	133.21	64.152	0.69614	0.180	0.0462
open field	distance traveled, 20 min test, 2nd 5min	8.2961	54.334	-0.39757	0.945	0.880
open field	distance traveled, 20 min test, 3rd 5min	-61.936	58.351	-1.1257	0.549	0.297
open field	distance traveled, 20 min test, 4th 5min	-101.03	52.128	-1.6162	0.226	0.0621
open field	number of clockwise revolution episodes, 20 min test	-0.99389	0.84429	-1.0385	0.606	0.248
open field	number of counter-clockwise revolution episodes, 20 min test	-2.5659	1.3646	-1.9570	0.288	0.0695
open field	number of rears in 5 min bins, 20 min test, 1st 5min	4.1565	3.4255	0.91716	0.499	0.234
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	-2.2589	3.9126	-0.91345	0.781	0.568
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	-6.1812	4.0833	-1.6415	0.395	0.141
open field	number of rears in 5 min bins, 20 min test, 4th 5min	-5.3179	4.1263	-1.5114	0.475	0.207
open field	percentage of total time in center of arena, 20 min test	-6.3771	2.8828	-1.7549	0.234	0.0345
open field	percentage of total time in center of arena, slope, 20 min test	-1.5283	1.6269	-0.72203	0.794	0.355
open field	percentage of total time in center, habituation ratio, 20 min test	-1.7079	1.7924	-0.77534	0.798	0.348
open field	percentage of total time in corners of arena, 20 min test	4.7681	2.8740	1.1487	0.400	0.107
open field	percentage of total time in corners, habituation ratio, 20 min test	1.3256	2.1034	0.30754	0.884	0.533
open field	percentage of total time in corners, slope, 20 min test	1.6843	2.0221	0.49398	0.839	0.411
open field	permanence time in center of arena, 20 min test	-76.546	34.594	-1.7549	0.234	0.0344
open field	permanence time in corners of arena, 20 min test	57.197	34.490	1.1487	0.401	0.107
open field	permanence time in periphery of arena, 20 min test	76.548	34.594	1.7549	0.234	0.0344
open field	total distance traveled, 20 min test	-34.116	188.04	-0.59844	0.927	0.857
open field	total number of rears, 20 min test	-10.085	13.871	-1.0504	0.704	0.473
open field	whole arena average speed, 20 min test	-0.028221	0.15638	-0.59684	0.927	0.858
open field	whole arena resting time, 20 min test	24.761	18.728	1.2333	0.385	0.196
open field	whole arena time spent mobile, 20 min test	-2.9614	3.4264	-0.67407	0.606	0.394
open field	whole arena time spent vertical, 20 min test	3.0408	7.6763	0.13128	0.881	0.695
startle / PPI	average baseline movement during background noise	0.78734	2.2204	0.59437	0.948	0.726
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	-0.18557	0.088959	-1.6809	0.303	0.0494
startle / PPI	average of each corrected percent pre-pulse inhibition value	-0.16830	0.081077	-1.6979	0.314	0.0504
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-7.6286	10.152	-0.79041	0.887	0.461
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-11.656	6.9374	-1.2025	0.447	0.108
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-16.848	6.6450	-1.6583	0.148	0.0192
startle / PPI	average startle response to full pulse (120 dB)	11.174	44.782	0.48257	0.922	0.805
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.36043	38.712	0.18530	0.995	0.993
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	23.008	34.843	0.67141	0.708	0.516
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	42.655	28.088	1.1200	0.340	0.144
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	-2.0702	1.1954	-1.3833	0.626	0.0980
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	-0.23892	1.5651	-0.15545	0.977	0.880
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	1.2561	1.7857	0.40372	0.821	0.490
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.14293	0.12795	-1.2379	0.858	0.277
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.16704	0.090803	-1.4679	0.374	0.0800
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-0.20300	0.076522	-1.7101	0.109	0.0149
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	10.387	45.335	0.47471	0.931	0.821
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	2.0870	39.055	0.22106	0.980	0.958
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	23.434	34.985	0.69085	0.703	0.510
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	41.025	28.482	1.1096	0.360	0.165
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.13909	0.14597	-1.1359	0.860	0.352
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.17873	0.093612	-1.4723	0.347	0.0707
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-0.24464	0.072600	-1.8617	0.0437	0.00290
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	39.405	156.14	0.42050	0.921	0.803
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	-3.5670	146.20	0.16112	0.992	0.981
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	106.44	127.18	0.76575	0.620	0.412
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	192.30	103.83	1.2781	0.231	0.0781
startle / PPI	maximum baseline movement during background noise	-1.6647	7.2877	-0.45442	0.964	0.822
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-9.0291	12.168	-0.84722	0.910	0.466
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-14.795	7.6248	-1.3653	0.373	0.0666
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-21.947	6.9000	-1.8541	0.0682	0.00450
startle / PPI	maximum startle response to full pulse (120 dB)	37.740	154.91	0.41286	0.920	0.810
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-10.094	145.09	0.13138	0.967	0.945
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	105.91	126.82	0.75826	0.622	0.413
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	195.92	102.58	1.2844	0.218	0.0699
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	-7.5806	2.4895	-1.8863	0.297	0.00615
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	0.27751	3.5958	0.10880	0.996	0.939
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	3.2432	4.5245	0.41286	0.809	0.482

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

In this plot, data points are the computed genotype effect % vs. C57BL/6NJ controls, for all measured categorical phenotypes in JaxKOMP-EAP

Dimensions Width: × Height: px

Plot Options Group by Procedure

Include Sexes Data Both Females Males

Significance Threshold p-Value Threshold

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Procedure	JaxKOMP-EAP Trait	Sex	Trait Effect	P-value

eye morphology	anterior chamber depth	females	1.0 %	1.0
eye morphology	anterior chamber depth	males	0.0 %	1.0
eye morphology	anterior chamber depth	both	1.0 %	1.0
eye morphology	bulging eye	females	1.0 %	1.0
eye morphology	bulging eye	males	0.0 %	1.0
eye morphology	bulging eye	both	1.0 %	1.00
eye morphology	cornea	females	4.0 %	1.0
eye morphology	cornea	males	2.0 %	1.0
eye morphology	cornea	both	3.0 %	1.00
eye morphology	cornea opacity	females	9.0 %	0.359
eye morphology	cornea opacity	males	1.0 %	1.0
eye morphology	cornea opacity	both	5.0 %	0.408
eye morphology	cornea vascularization	females	3.0 %	1.0
eye morphology	cornea vascularization	males	1.0 %	1.0
eye morphology	cornea vascularization	both	2.0 %	1.0
eye morphology	corneal deposits	females	2.0 %	1.0
eye morphology	corneal deposits	males	1.0 %	1.0
eye morphology	corneal deposits	both	1.0 %	1.00
eye morphology	corneal mineralization	females	2.0 %	1.0
eye morphology	corneal mineralization	males	1.0 %	1.0
eye morphology	corneal mineralization	both	1.0 %	1.0
eye morphology	corneal scleralization	females	3.0 %	1.00
eye morphology	corneal scleralization	males	1.0 %	1.0
eye morphology	corneal scleralization	both	2.0 %	1.0
eye morphology	corneal ulcer	females	1.0 %	1.0
eye morphology	corneal ulcer	males	1.0 %	1.0
eye morphology	corneal ulcer	both	1.0 %	1.0
eye morphology	eye closure	females	1.0 %	1.00
eye morphology	eye closure	males	0.0 %	1.0
eye morphology	eye closure	both	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	females	2.0 %	1.00
eye morphology	eye hemorrhage or blood presence	males	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	both	1.0 %	1.0
eye morphology	eyelid morphology	females	1.0 %	1.0
eye morphology	eyelid morphology	males	0.0 %	1.0
eye morphology	eyelid morphology	both	1.0 %	1.0
eye morphology	eyes (present, absent)	females	1.0 %	1.0
eye morphology	eyes (present, absent)	males	0.0 %	1.0
eye morphology	eyes (present, absent)	both	0.0 %	1.0
eye morphology	fusion between cornea and lens	females	4.0 %	1.00
eye morphology	fusion between cornea and lens	males	2.0 %	1.0
eye morphology	fusion between cornea and lens	both	3.0 %	1.0
eye morphology	iris pigmentation	females	2.0 %	1.0
eye morphology	iris pigmentation	males	1.0 %	1.0
eye morphology	iris pigmentation	both	2.0 %	1.0
eye morphology	iris transillumination	females	2.0 %	1.00
eye morphology	iris transillumination	males	1.0 %	1.00
eye morphology	iris transillumination	both	1.0 %	1.00
eye morphology	irispupil	females	4.0 %	1.00
eye morphology	irispupil	males	13.0 %	0.198
eye morphology	irispupil	both	5.0 %	0.415
eye morphology	lacrimation	females	3.0 %	1.0
eye morphology	lacrimation	males	2.0 %	1.0
eye morphology	lacrimation	both	3.0 %	1.0
eye morphology	lens	females	10.0 %	1.00
eye morphology	lens	males	8.0 %	1.00
eye morphology	lens	both	9.0 %	1.0
eye morphology	lens opacity	females	9.0 %	1.0
eye morphology	lens opacity	males	6.0 %	1.00
eye morphology	lens opacity	both	7.0 %	1.00
eye morphology	narrow eye opening	females	12.0 %	0.171
eye morphology	narrow eye opening	males	1.0 %	1.0
eye morphology	narrow eye opening	both	6.0 %	0.135
eye morphology	optic disc	females	4.0 %	1.00
eye morphology	optic disc	males	2.0 %	1.00
eye morphology	optic disc	both	3.0 %	1.00
eye morphology	persistence of hyaloid vascular system	females	6.0 %	0.690
eye morphology	persistence of hyaloid vascular system	males	5.0 %	1.0
eye morphology	persistence of hyaloid vascular system	both	3.0 %	0.769
eye morphology	pupil dilation	females	2.0 %	1.0
eye morphology	pupil dilation	males	1.0 %	1.00
eye morphology	pupil dilation	both	2.0 %	1.0
eye morphology	pupil light response	females	2.0 %	1.00
eye morphology	pupil light response	males	1.0 %	1.0
eye morphology	pupil light response	both	2.0 %	1.0
eye morphology	pupil position	females	4.0 %	1.00
eye morphology	pupil position	males	13.0 %	0.205
eye morphology	pupil position	both	5.0 %	0.440
eye morphology	pupil shape	females	3.0 %	1.00
eye morphology	pupil shape	males	2.0 %	1.0
eye morphology	pupil shape	both	3.0 %	1.0
eye morphology	retina	females	10.0 %	1.0
eye morphology	retina	males	13.0 %	0.356
eye morphology	retina	both	3.0 %	0.693
eye morphology	retinal blood vessels	females	4.0 %	1.0
eye morphology	retinal blood vessels	males	2.0 %	1.0
eye morphology	retinal blood vessels	both	3.0 %	1.0
eye morphology	retinal blood vessels pattern	females	12.0 %	0.139
eye morphology	retinal blood vessels pattern	males	2.0 %	1.00
eye morphology	retinal blood vessels pattern	both	6.0 %	0.160
eye morphology	retinal blood vessels structure	females	4.0 %	1.00
eye morphology	retinal blood vessels structure	males	2.0 %	1.0
eye morphology	retinal blood vessels structure	both	3.0 %	1.0
eye morphology	retinal pigmentation	females	12.0 %	1.0
eye morphology	retinal pigmentation	males	14.0 %	1.0
eye morphology	retinal pigmentation	both	13.0 %	1.0
eye morphology	retinal structure	females	4.0 %	1.00
eye morphology	retinal structure	males	2.0 %	1.00
eye morphology	retinal structure	both	3.0 %	1.00
eye morphology	synechia	females	4.0 %	1.0
eye morphology	synechia	males	2.0 %	1.00
eye morphology	synechia	both	3.0 %	1.00
eye morphology	vitreous	females	4.0 %	1.00
eye morphology	vitreous	males	2.0 %	1.0
eye morphology	vitreous	both	3.0 %	1.0
SHIRPA	activity body position	females	1.0 %	1.0
SHIRPA	activity body position	males	2.0 %	1.0
SHIRPA	activity body position	both	1.0 %	1.00
SHIRPA	aggression	females	0.0 %	1.00
SHIRPA	aggression	males	1.0 %	1.0
SHIRPA	aggression	both	1.0 %	1.0
SHIRPA	body length	females	0.0 %	1.0
SHIRPA	body length	males	0.0 %	1.0
SHIRPA	body length	both	0.0 %	1.0
SHIRPA	body position	females	0.0 %	1.0
SHIRPA	body position	males	1.0 %	1.00
SHIRPA	body position	both	0.0 %	1.00
SHIRPA	body thickness	females	1.0 %	1.0
SHIRPA	body thickness	males	0.0 %	1.0
SHIRPA	body thickness	both	0.0 %	1.0
SHIRPA	coat color abdomen	females	3.0 %	1.00
SHIRPA	coat color abdomen	males	4.0 %	1.00
SHIRPA	coat color abdomen	both	4.0 %	1.0
SHIRPA	coat color back	females	0.0 %	1.0
SHIRPA	coat color back	males	0.0 %	1.00
SHIRPA	coat color back	both	0.0 %	1.0
SHIRPA	coat color head	females	0.0 %	1.0
SHIRPA	coat color head	males	0.0 %	1.00
SHIRPA	coat color head	both	0.0 %	1.0
SHIRPA	coat color pattern abdomen	females	1.0 %	1.0
SHIRPA	coat color pattern abdomen	males	1.0 %	1.0
SHIRPA	coat color pattern abdomen	both	1.0 %	1.00
SHIRPA	coat color pattern back	females	0.0 %	1.0
SHIRPA	coat color pattern back	males	0.0 %	1.00
SHIRPA	coat color pattern back	both	0.0 %	1.0
SHIRPA	coat color pattern head	females	0.0 %	1.0
SHIRPA	coat color pattern head	males	0.0 %	1.0
SHIRPA	coat color pattern head	both	0.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	females	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	males	2.0 %	1.00
SHIRPA	coat hair abdomen texture appearance	both	2.0 %	1.0
SHIRPA	coat hair back texture appearance	females	0.0 %	1.0
SHIRPA	coat hair back texture appearance	males	0.0 %	1.00
SHIRPA	coat hair back texture appearance	both	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	females	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	males	1.0 %	1.0
SHIRPA	coat hair distribution abdomen	both	1.0 %	1.00
SHIRPA	coat hair distribution back	females	0.0 %	1.0
SHIRPA	coat hair distribution back	males	0.0 %	1.0
SHIRPA	coat hair distribution back	both	0.0 %	1.0
SHIRPA	coat hair distribution head	females	1.0 %	1.00
SHIRPA	coat hair distribution head	males	1.0 %	1.00
SHIRPA	coat hair distribution head	both	1.0 %	1.0
SHIRPA	coat hair head texture appearance	females	0.0 %	1.00
SHIRPA	coat hair head texture appearance	males	0.0 %	1.0
SHIRPA	coat hair head texture appearance	both	0.0 %	1.0
SHIRPA	contact righting	females	5.0 %	1.0
SHIRPA	contact righting	males	5.0 %	1.0
SHIRPA	contact righting	both	5.0 %	1.00
SHIRPA	ear morphology	females	0.0 %	1.0
SHIRPA	ear morphology	males	0.0 %	1.0
SHIRPA	ear morphology	both	0.0 %	1.0
SHIRPA	fat distribution	females	0.0 %	1.0
SHIRPA	fat distribution	males	0.0 %	1.0
SHIRPA	fat distribution	both	0.0 %	1.0
SHIRPA	forelimb digit number	females	0.0 %	1.00
SHIRPA	forelimb digit number	males	0.0 %	1.0
SHIRPA	forelimb digit number	both	0.0 %	1.0
SHIRPA	forelimb digit position	females	0.0 %	1.0
SHIRPA	forelimb digit position	males	0.0 %	1.0
SHIRPA	forelimb digit position	both	0.0 %	1.0
SHIRPA	forelimb digit shape	females	0.0 %	1.0
SHIRPA	forelimb digit shape	males	0.0 %	1.0
SHIRPA	forelimb digit shape	both	0.0 %	1.0
SHIRPA	forelimb digit size	females	0.0 %	1.0
SHIRPA	forelimb digit size	males	0.0 %	1.0
SHIRPA	forelimb digit size	both	0.0 %	1.0
SHIRPA	forelimb footpads	females	0.0 %	1.0
SHIRPA	forelimb footpads	males	0.0 %	1.0
SHIRPA	forelimb footpads	both	0.0 %	1.0
SHIRPA	forelimb nail length	females	0.0 %	1.0
SHIRPA	forelimb nail length	males	0.0 %	1.0
SHIRPA	forelimb nail length	both	0.0 %	1.0
SHIRPA	forelimb nail number	females	0.0 %	1.0
SHIRPA	forelimb nail number	males	0.0 %	1.0
SHIRPA	forelimb nail number	both	0.0 %	1.0
SHIRPA	forelimb nail position	females	0.0 %	1.0
SHIRPA	forelimb nail position	males	0.0 %	1.0
SHIRPA	forelimb nail position	both	0.0 %	1.0
SHIRPA	forelimb nail shape	females	0.0 %	1.0
SHIRPA	forelimb nail shape	males	0.0 %	1.0
SHIRPA	forelimb nail shape	both	0.0 %	1.0
SHIRPA	forelimbs position	females	0.0 %	1.0
SHIRPA	forelimbs position	males	0.0 %	1.0
SHIRPA	forelimbs position	both	0.0 %	1.0
SHIRPA	forelimbs shape	females	0.0 %	1.0
SHIRPA	forelimbs shape	males	0.0 %	1.0
SHIRPA	forelimbs shape	both	0.0 %	1.0
SHIRPA	forelimbs size	females	0.0 %	1.0
SHIRPA	forelimbs size	males	0.0 %	1.0
SHIRPA	forelimbs size	both	0.0 %	1.0
SHIRPA	forepaw position	females	0.0 %	1.0
SHIRPA	forepaw position	males	0.0 %	1.0
SHIRPA	forepaw position	both	0.0 %	1.0
SHIRPA	forepaw shape	females	0.0 %	1.0
SHIRPA	forepaw shape	males	0.0 %	1.0
SHIRPA	forepaw shape	both	0.0 %	1.0
SHIRPA	forepaw size	females	0.0 %	1.0
SHIRPA	forepaw size	males	0.0 %	1.0
SHIRPA	forepaw size	both	0.0 %	1.0
SHIRPA	gait (fluidity)	females	0.0 %	1.0
SHIRPA	gait (fluidity)	males	0.0 %	1.0
SHIRPA	gait (fluidity)	both	0.0 %	1.0
SHIRPA	genitalia morphology	females	0.0 %	1.00
SHIRPA	genitalia morphology	males	0.0 %	1.0
SHIRPA	genitalia morphology	both	0.0 %	1.00
SHIRPA	genitalia presence	females	0.0 %	1.0
SHIRPA	genitalia presence	males	0.0 %	1.0
SHIRPA	genitalia presence	both	0.0 %	1.0
SHIRPA	genitalia size	females	0.0 %	1.0
SHIRPA	genitalia size	males	0.0 %	1.0
SHIRPA	genitalia size	both	0.0 %	1.0
SHIRPA	head bobbing	females	0.0 %	1.0
SHIRPA	head bobbing	males	0.0 %	1.0
SHIRPA	head bobbing	both	0.0 %	1.0
SHIRPA	head morphology	females	0.0 %	1.0
SHIRPA	head morphology	males	0.0 %	1.0
SHIRPA	head morphology	both	0.0 %	1.0
SHIRPA	head size	females	0.0 %	1.0
SHIRPA	head size	males	0.0 %	1.0
SHIRPA	head size	both	0.0 %	1.0
SHIRPA	hindlimb digit number	females	1.0 %	1.00
SHIRPA	hindlimb digit number	males	0.0 %	1.0
SHIRPA	hindlimb digit number	both	0.0 %	1.0
SHIRPA	hindlimb digit position	females	0.0 %	1.0
SHIRPA	hindlimb digit position	males	0.0 %	1.0
SHIRPA	hindlimb digit position	both	0.0 %	1.0
SHIRPA	hindlimb digit shape	females	0.0 %	1.0
SHIRPA	hindlimb digit shape	males	0.0 %	1.0
SHIRPA	hindlimb digit shape	both	0.0 %	1.0
SHIRPA	hindlimb digit size	females	0.0 %	1.00
SHIRPA	hindlimb digit size	males	0.0 %	1.0
SHIRPA	hindlimb digit size	both	0.0 %	1.00
SHIRPA	hindlimb nail length	females	0.0 %	1.0
SHIRPA	hindlimb nail length	males	0.0 %	1.0
SHIRPA	hindlimb nail length	both	0.0 %	1.0
SHIRPA	hindlimb nail number	females	0.0 %	1.0
SHIRPA	hindlimb nail number	males	1.0 %	1.0
SHIRPA	hindlimb nail number	both	0.0 %	1.0
SHIRPA	hindlimb nail position	females	0.0 %	1.0
SHIRPA	hindlimb nail position	males	0.0 %	1.0
SHIRPA	hindlimb nail position	both	0.0 %	1.0
SHIRPA	hindlimb nail shape	females	0.0 %	1.0
SHIRPA	hindlimb nail shape	males	0.0 %	1.0
SHIRPA	hindlimb nail shape	both	0.0 %	1.0
SHIRPA	hindlimbs footpads	females	0.0 %	1.0
SHIRPA	hindlimbs footpads	males	0.0 %	1.0
SHIRPA	hindlimbs footpads	both	0.0 %	1.0
SHIRPA	hindlimbs position	females	0.0 %	1.0
SHIRPA	hindlimbs position	males	0.0 %	1.0
SHIRPA	hindlimbs position	both	0.0 %	1.0
SHIRPA	hindlimbs shape	females	0.0 %	1.0
SHIRPA	hindlimbs shape	males	0.0 %	1.0
SHIRPA	hindlimbs shape	both	0.0 %	1.0
SHIRPA	hindlimbs size	females	0.0 %	1.0
SHIRPA	hindlimbs size	males	0.0 %	1.0
SHIRPA	hindlimbs size	both	0.0 %	1.0
SHIRPA	hindpaw position	females	0.0 %	1.0
SHIRPA	hindpaw position	males	0.0 %	1.0
SHIRPA	hindpaw position	both	0.0 %	1.0
SHIRPA	hindpaw shape	females	0.0 %	1.0
SHIRPA	hindpaw shape	males	0.0 %	1.0
SHIRPA	hindpaw shape	both	0.0 %	1.0
SHIRPA	hindpaw size	females	0.0 %	1.0
SHIRPA	hindpaw size	males	0.0 %	1.0
SHIRPA	hindpaw size	both	0.0 %	1.0
SHIRPA	limb grasp	females	9.0 %	1.00
SHIRPA	limb grasp	males	6.0 %	1.0
SHIRPA	limb grasp	both	7.0 %	1.0
SHIRPA	lower lip morphology	females	0.0 %	1.0
SHIRPA	lower lip morphology	males	0.0 %	1.0
SHIRPA	lower lip morphology	both	0.0 %	1.0
SHIRPA	lower teeth appearance	females	0.0 %	1.0
SHIRPA	lower teeth appearance	males	0.0 %	1.00
SHIRPA	lower teeth appearance	both	0.0 %	1.00
SHIRPA	mouth morphology	females	0.0 %	1.0
SHIRPA	mouth morphology	males	0.0 %	1.0
SHIRPA	mouth morphology	both	0.0 %	1.0
SHIRPA	salivation	females	0.0 %	1.0
SHIRPA	salivation	males	0.0 %	1.0
SHIRPA	salivation	both	0.0 %	1.0
SHIRPA	skin color back paws	females	0.0 %	1.0
SHIRPA	skin color back paws	males	0.0 %	1.0
SHIRPA	skin color back paws	both	0.0 %	1.0
SHIRPA	skin color ear	females	0.0 %	1.0
SHIRPA	skin color ear	males	0.0 %	1.0
SHIRPA	skin color ear	both	0.0 %	1.0
SHIRPA	skin color front paws	females	0.0 %	1.0
SHIRPA	skin color front paws	males	0.0 %	1.0
SHIRPA	skin color front paws	both	0.0 %	1.0
SHIRPA	skin color snout	females	0.0 %	1.0
SHIRPA	skin color snout	males	0.0 %	1.0
SHIRPA	skin color snout	both	0.0 %	1.0
SHIRPA	skin color tail	females	0.0 %	1.0
SHIRPA	skin color tail	males	0.0 %	1.0
SHIRPA	skin color tail	both	0.0 %	1.0
SHIRPA	skin color whole body	females	0.0 %	1.0
SHIRPA	skin color whole body	males	0.0 %	1.0
SHIRPA	skin color whole body	both	0.0 %	1.0
SHIRPA	skin texture back paw	females	0.0 %	1.0
SHIRPA	skin texture back paw	males	0.0 %	1.0
SHIRPA	skin texture back paw	both	0.0 %	1.0
SHIRPA	skin texture ear	females	0.0 %	1.0
SHIRPA	skin texture ear	males	0.0 %	1.0
SHIRPA	skin texture ear	both	0.0 %	1.0
SHIRPA	skin texture front paws	females	0.0 %	1.0
SHIRPA	skin texture front paws	males	0.0 %	1.0
SHIRPA	skin texture front paws	both	0.0 %	1.0
SHIRPA	skin texture snout	females	0.0 %	1.0
SHIRPA	skin texture snout	males	0.0 %	1.0
SHIRPA	skin texture snout	both	0.0 %	1.0
SHIRPA	skin texture tail	females	0.0 %	1.0
SHIRPA	skin texture tail	males	0.0 %	1.0
SHIRPA	skin texture tail	both	0.0 %	1.0
SHIRPA	skin texture whole body	females	0.0 %	1.0
SHIRPA	skin texture whole body	males	0.0 %	1.0
SHIRPA	skin texture whole body	both	0.0 %	1.0
SHIRPA	snout size	females	0.0 %	1.0
SHIRPA	snout size	males	1.0 %	1.0
SHIRPA	snout size	both	0.0 %	1.0
SHIRPA	startle response	females	0.0 %	1.00
SHIRPA	startle response	males	0.0 %	1.0
SHIRPA	startle response	both	0.0 %	1.0
SHIRPA	tail curvature	females	0.0 %	1.00
SHIRPA	tail curvature	males	0.0 %	1.0
SHIRPA	tail curvature	both	0.0 %	1.00
SHIRPA	tail elevation	females	1.0 %	1.00
SHIRPA	tail elevation	males	2.0 %	1.0
SHIRPA	tail elevation	both	1.0 %	1.0
SHIRPA	tail length	females	0.0 %	1.0
SHIRPA	tail length	males	0.0 %	1.0
SHIRPA	tail length	both	0.0 %	1.00
SHIRPA	tail morphology	females	0.0 %	1.00
SHIRPA	tail morphology	males	0.0 %	1.0
SHIRPA	tail morphology	both	0.0 %	1.0
SHIRPA	tail presence	females	0.0 %	1.0
SHIRPA	tail presence	males	0.0 %	1.0
SHIRPA	tail presence	both	0.0 %	1.0
SHIRPA	tail shape	females	0.0 %	1.0
SHIRPA	tail shape	males	0.0 %	1.0
SHIRPA	tail shape	both	0.0 %	1.00
SHIRPA	tail thickness	females	0.0 %	1.0
SHIRPA	tail thickness	males	0.0 %	1.0
SHIRPA	tail thickness	both	0.0 %	1.0
SHIRPA	teeth presence	females	0.0 %	1.0
SHIRPA	teeth presence	males	0.0 %	1.0
SHIRPA	teeth presence	both	0.0 %	1.00
SHIRPA	transfer arousal	females	1.0 %	1.0
SHIRPA	transfer arousal	males	2.0 %	1.0
SHIRPA	transfer arousal	both	1.0 %	1.0
SHIRPA	tremor	females	0.0 %	1.0
SHIRPA	tremor	males	0.0 %	1.0
SHIRPA	tremor	both	0.0 %	1.0
SHIRPA	trunk curl	females	0.0 %	1.00
SHIRPA	trunk curl	males	0.0 %	1.0
SHIRPA	trunk curl	both	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	females	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	males	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	both	0.0 %	1.0
SHIRPA	upper lip morphology	females	0.0 %	1.0
SHIRPA	upper lip morphology	males	0.0 %	1.0
SHIRPA	upper lip morphology	both	0.0 %	1.0
SHIRPA	upper teeth appearance	females	0.0 %	1.0
SHIRPA	upper teeth appearance	males	0.0 %	1.0
SHIRPA	upper teeth appearance	both	0.0 %	1.00
SHIRPA	vibrissae appearance	females	2.0 %	1.0
SHIRPA	vibrissae appearance	males	1.0 %	1.0
SHIRPA	vibrissae appearance	both	1.0 %	1.0
SHIRPA	vibrissae presence	females	2.0 %	1.00
SHIRPA	vibrissae presence	males	1.0 %	1.0
SHIRPA	vibrissae presence	both	2.0 %	1.00
SHIRPA	vocalization	females	2.0 %	1.00
SHIRPA	vocalization	males	2.0 %	1.00
SHIRPA	vocalization	both	2.0 %	1.0

GENOTYPE CORRELATION PLOT

Correlate Zdhhc22^em1(IMPC)J/Mmjax -/- with genotype: