MPD: JaxKOMP-EAP genotype: Grxcr1<sup>em1(IMPC)J</sup>/Mmjax -/-

JaxKOMP-EAP effect sizes: Grxcr1^em1(IMPC)J/Mmjax -/- Gene Grxcr1

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

In this plot, data points are the computed genotype effect size vs. C57BL/6NJ controls, for all measured numeric phenotypes in JaxKOMP-EAP

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Plot Options Group by Procedure Standard Error Show Effect Sizes RankZ

Significance Threshold p-Value Threshold Adjusted Unadjusted

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Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value

ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	56.684	2.9125	2.9291	4.21e-7	7.16e-10
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	50.082	3.2679	3.2578	0.0000109	9.09e-9
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	33.149	2.7908	3.2589	0.0000484	5.42e-8
body composition	body length	0.0021798	0.072184	0.23778	0.993	0.976
body composition	body weight (at time of DXA)	-1.4176	0.95833	-0.89006	0.352	0.155
body composition	bone area, whole body scan, head excluded	-0.096422	0.29272	-0.19927	0.886	0.746
body composition	bone mineral content of whole body scan, head excluded	-0.0088043	0.021209	-0.36277	0.856	0.683
body composition	bone mineral content to body weight ratio	0.0010832	0.00053502	1.6030	0.226	0.0580
body composition	bone mineral density of whole body scan, head excluded	-0.0010235	0.00061538	-1.0535	0.360	0.113
body composition	fat tissue mass of whole body scan, head excluded	-0.13596	0.26286	-0.23703	0.802	0.611
body composition	fat tissue mass to body weight ratio	-0.011359	0.011191	-0.48532	0.568	0.324
body composition	lean tissue mass of whole body scan, head excluded	-0.88800	0.51191	-1.7106	0.362	0.0999
body composition	lean tissue mass to body weight ratio	0.017129	0.013736	0.84357	0.484	0.228
body composition	percent fat, whole body scan, head excluded	-1.1026	1.0087	-0.50538	0.537	0.289
body composition	ratio of soft-tissue attenuation coefficients	0.0012172	0.0011211	0.49573	0.544	0.292
body composition	tissue area	0.20303	0.56468	0.82192	0.903	0.723
body composition	total tissue mass, whole body scan, head excluded	0.72071	0.58137	1.1896	0.473	0.231
clinical blood chemistry	alanine transaminase (plasma ALT)	4.4963	2.5897	0.36427	0.441	0.0965
clinical blood chemistry	albumin (plasma Alb)	1.0139	0.41849	1.5153	0.185	0.0241
clinical blood chemistry	alkaline phosphatase (plasma ALP)	-10.571	2.5543	-2.0949	0.00951	0.000430
clinical blood chemistry	aspartate transaminase (plasma AST)	0.15889	3.3074	0.0085068	0.986	0.962
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	-0.18715	0.11010	-0.59717	0.480	0.103
clinical blood chemistry	blood urea nitrogen (BUN)	0.85037	1.4347	0.30191	0.770	0.559
clinical blood chemistry	calcium (plasma Ca)	-0.035847	0.059110	0.088980	0.742	0.551
clinical blood chemistry	creatinine (plasma)	-0.040613	0.013673	-0.80267	0.0589	0.00706
clinical blood chemistry	glucose (plasma GLU, no fast)	18.155	14.594	1.0058	0.427	0.227
clinical blood chemistry	HDL cholesterol (plasma HDL)	4.5696	3.4111	0.72748	0.495	0.195
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	-0.0095118	0.0093024	-0.66958	0.643	0.318
clinical blood chemistry	phosphorus (plasma phosphate)	-0.80252	0.31760	-1.2910	0.136	0.0192
clinical blood chemistry	total bilirubin (plasma TBIL)	0.013106	0.0055552	0.82595	0.200	0.0276
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	5.1739	5.2811	0.66160	0.647	0.338
clinical blood chemistry	total protein (plasma TP)	1.0949	0.71745	0.80595	0.417	0.141
clinical blood chemistry	triglyceride (plasma TG, no fast)	-33.263	31.594	-1.3943	0.597	0.304
ERG v2.0	left eye a-wave amplitude (Photopic)	-3.6960	1.9141	-1.0886	0.457	0.0823
ERG v2.0	left eye a-wave amplitude (Scotopic)	-21.882	19.047	-0.84950	0.632	0.275
ERG v2.0	left eye a-wave implicit timing (Photopic)	-1.8898	0.61894	-0.75817	0.232	0.0110
ERG v2.0	left eye a-wave implicit timing (Scotopic)	0.24378	0.68321	0.27269	0.903	0.728
ERG v2.0	left eye b-wave amplitude (Photopic)	-1.5270	4.9249	-0.32443	0.922	0.762
ERG v2.0	left eye b-wave amplitude (Scotopic)	64.240	38.151	0.96596	0.517	0.120
ERG v2.0	left eye b-wave implicit timing (Photopic)	0.68584	3.0788	0.33604	0.944	0.828
ERG v2.0	left eye b-wave implicit timing (Scotopic)	0.54792	8.0149	0.10209	0.984	0.947
ERG v2.0	left eye c-wave amplitude (Scotopic)	35.377	27.986	0.90770	0.653	0.232
ERG v2.0	left eye c-wave implicit timing (Scotopic)	236.96	123.58	1.4910	0.482	0.0815
ERG v2.0	left eye FO-like wave amplitude (Scotopic)	-13.960	40.125	-0.40672	0.874	0.734
ERG v2.0	left eye FO-like wave implicit timing (Scotopic)	-233.05	266.48	-0.72911	0.844	0.402
ERG v2.0	right eye a-wave amplitude (Photopic)	10.951	3.0315	2.3751	0.114	0.00475
ERG v2.0	right eye a-wave amplitude (Scotopic)	8.7365	16.521	0.038488	0.897	0.607
ERG v2.0	right eye a-wave implicit timing (Photopic)	-5.5145	1.8973	-2.2907	0.240	0.0143
ERG v2.0	right eye a-wave implicit timing (Scotopic)	-0.022034	0.59693	0.0	0.982	0.971
ERG v2.0	right eye b-wave amplitude (Photopic)	-3.6773	6.6181	-0.54852	0.877	0.591
ERG v2.0	right eye b-wave amplitude (Scotopic)	-9.4159	39.545	0.010994	0.982	0.816
ERG v2.0	right eye b-wave implicit timing (Photopic)	0.77641	1.9776	0.35354	0.885	0.702
ERG v2.0	right eye b-wave implicit timing (Scotopic)	-10.262	9.3348	-0.99410	0.792	0.297
ERG v2.0	right eye c-wave amplitude (Scotopic)	-36.509	20.500	-0.51685	0.536	0.103
ERG v2.0	right eye c-wave implicit timing (Scotopic)	-101.06	84.361	-0.95721	0.751	0.256
ERG v2.0	right eye FO-like wave amplitude (Scotopic)	43.041	32.844	0.38888	0.613	0.217
ERG v2.0	right eye FO-like wave implicit timing (Scotopic)	-308.93	253.13	-0.95868	0.801	0.248
glucose tolerance test	amount glucose injected	9.2257	7.5347	2.1071	0.621	0.237
glucose tolerance test	plasma glucose, 0min	-14.032	3.8653	-1.4091	0.0176	0.00178
glucose tolerance test	plasma glucose, 15min	-42.261	26.259	-1.0245	0.416	0.124
glucose tolerance test	plasma glucose, 30min	26.634	26.049	0.90639	0.647	0.320
glucose tolerance test	plasma glucose, 60min	1.6576	15.813	0.19618	0.963	0.918
glucose tolerance test	plasma glucose, 120min	-18.123	14.145	-1.3453	0.526	0.216
grip strength	body weight (at time of grip strength test)	-0.18012	0.42480	0.043532	0.810	0.674
grip strength	forelimb and hindlimb grip strength (mean of trials), average	-0.15111	3.0544	0.22853	0.978	0.961
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	-0.21652	0.16674	-0.11060	0.398	0.202
grip strength	forelimb and hindlimb grip strength by trial, trial1	-0.62962	5.2740	0.18698	0.961	0.906
grip strength	forelimb and hindlimb grip strength by trial, trial2	0.14574	4.7369	0.23002	0.989	0.976
grip strength	forelimb and hindlimb grip strength by trial, trial3	0.41218	4.7299	0.22853	0.974	0.931
grip strength	forelimb grip strength (mean of trials), average	3.2352	3.3144	0.71986	0.595	0.335
grip strength	forelimb grip strength (mean of trials), average normalized to bw	0.011220	0.15221	0.26897	0.977	0.942
grip strength	forelimb grip strength by trial, trial1	7.7511	4.4732	1.1610	0.357	0.0910
grip strength	forelimb grip strength by trial, trial2	0.99698	4.7302	0.32055	0.942	0.834
grip strength	forelimb grip strength by trial, trial3	0.95135	4.7983	0.36522	0.937	0.844
heart weight	heart weight, normalized to body weight	-0.0048235	0.20552	-0.46408	0.989	0.981
heart weight	heart weight, weight	-0.69289	4.3223	-0.45058	0.929	0.874
hematology	basophil differential (percent of total WBC)	0.055051	0.039152	0.82839	0.618	0.178
hematology	eosinophil differential (percent of total WBC)	0.14099	0.25041	0.49775	0.863	0.581
hematology	hematocrit (HCT)	-0.37880	0.98251	-0.72246	0.854	0.705
hematology	lymphocyte differential (percent of total WBC)	-0.010539	2.4363	-0.051960	0.997	0.997
hematology	mean corpuscular hemoglobin (CHr)	-0.015657	0.069704	-0.10597	0.914	0.825
hematology	mean platelet volume (MPV)	-0.095455	0.055471	-0.79634	0.270	0.103
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	0.40752	0.22676	0.84162	0.403	0.0901
hematology	mean RBC corpuscular volume (MCV)	-0.36033	0.31471	-0.66679	0.499	0.268
hematology	measured hemoglobin (mHGB)	0.21853	0.31309	0.32638	0.733	0.495
hematology	monocyte differential (percent of total WBC)	0.22777	0.81273	0.95154	0.920	0.783
hematology	neutrophil differential (percent of total WBC)	-1.4689	1.6904	-0.66850	0.616	0.397
hematology	platelet count (PLT; units per volume x 10³)	26.409	45.887	0.40290	0.827	0.572
hematology	RBC corpuscular distribution width (RDW)	-0.067489	0.21537	-0.24007	0.872	0.758
hematology	red blood cell count (RBC; per volume x 10⁶)	0.0074420	0.24619	-0.33018	0.986	0.976
hematology	reticulocyte count (Retic; units per volume x 10⁹)	12.216	14.271	0.62404	0.755	0.404
hematology	reticulocyte differential (percent of total RBC)	-0.030657	0.13118	0.10269	0.930	0.818
hematology	white blood cell count (WBC; units per volume x 10³)	1.3593	0.87991	1.0896	0.317	0.141
holeboard	number of hole pokes by individual hole number, 20 min test, 1	-2.3369	1.4557	-2.2124	0.620	0.115
holeboard	number of hole pokes by individual hole number, 20 min test, 2	-0.62033	0.59214	-0.81781	0.776	0.300
holeboard	number of hole pokes by individual hole number, 20 min test, 3	0.040023	0.42276	0.14824	0.976	0.925
holeboard	number of hole pokes by individual hole number, 20 min test, 4	-1.6807	1.1070	-1.6208	0.611	0.136
holeboard	number of hole pokes by individual hole number, 20 min test, 5	-0.60462	0.53714	-0.88824	0.767	0.266
holeboard	number of hole pokes by individual hole number, 20 min test, 6	0.72514	0.34637	1.5280	0.554	0.0416
holeboard	number of hole pokes by individual hole number, 20 min test, 7	0.21686	0.41419	0.59337	0.949	0.603
holeboard	number of hole pokes by individual hole number, 20 min test, 8	-0.26082	0.62185	-0.32553	0.937	0.677
holeboard	number of hole pokes by individual hole number, 20 min test, 9	-0.10364	0.55315	-0.098125	0.983	0.852
holeboard	number of hole pokes by individual hole number, 20 min test, 10	0.70475	0.45473	1.6013	0.728	0.128
holeboard	number of hole pokes by individual hole number, 20 min test, 11	0.80851	0.36838	1.6462	0.562	0.0330
holeboard	number of hole pokes by individual hole number, 20 min test, 12	0.59719	0.64714	1.0361	0.781	0.361
holeboard	number of hole pokes by individual hole number, 20 min test, 13	-0.28976	1.0253	-0.20727	0.939	0.779
holeboard	number of hole pokes by individual hole number, 20 min test, 14	0.75136	0.49325	1.1794	0.571	0.134
holeboard	number of hole pokes by individual hole number, 20 min test, 15	-0.66815	0.73829	-0.97192	0.790	0.370
holeboard	number of hole pokes by individual hole number, 20 min test, 16	-0.87725	1.6109	-0.73836	0.885	0.589
holeboard	total number of hole pokes, 20 min test	-4.8700	5.7068	-0.60514	0.667	0.398
open field	average speed in center of arena, 20 min test	0.78531	0.28351	1.2219	0.111	0.00800
open field	average speed in periphery of arena, 20 min test	0.32586	0.13070	0.71335	0.0785	0.0162
open field	distance traveled habituation ratio, 20 min test	44.444	10.851	2.5519	0.00857	0.000161
open field	distance traveled in center of arena, 20 min test	590.86	118.00	2.2147	0.000349	0.00000787
open field	distance traveled in periphery of arena, 20 min test	74.722	127.27	-0.14076	0.756	0.560
open field	distance traveled slope, 20 min test	41.777	10.656	2.5519	0.0122	0.000280
open field	distance traveled, 20 min test, 1st 5min	-60.556	58.415	-0.81963	0.548	0.305
open field	distance traveled, 20 min test, 2nd 5min	180.74	56.992	1.3245	0.0288	0.00267
open field	distance traveled, 20 min test, 3rd 5min	237.25	65.176	1.7425	0.0113	0.000677
open field	distance traveled, 20 min test, 4th 5min	314.17	75.633	2.0357	0.00319	0.000137
open field	number of clockwise revolution episodes, 20 min test	0.52196	1.0829	-0.098220	0.861	0.632
open field	number of counter-clockwise revolution episodes, 20 min test	2.1867	1.2534	0.70472	0.326	0.0876
open field	number of rears in 5 min bins, 20 min test, 1st 5min	0.86050	2.7142	0.014777	0.887	0.753
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	8.3995	3.0233	1.6162	0.0768	0.00778
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	7.4415	3.5473	1.3442	0.199	0.0413
open field	number of rears in 5 min bins, 20 min test, 4th 5min	13.978	3.8536	2.2641	0.0205	0.000704
open field	percentage of total time in center of arena, 20 min test	6.5478	2.9900	1.2478	0.234	0.0335
open field	percentage of total time in center of arena, slope, 20 min test	-0.46491	1.6483	-0.14619	0.952	0.779
open field	percentage of total time in center, habituation ratio, 20 min test	-1.0414	1.7329	-0.45045	0.868	0.551
open field	percentage of total time in corners of arena, 20 min test	-8.4922	2.6684	-1.2507	0.0537	0.00259
open field	percentage of total time in corners, habituation ratio, 20 min test	3.9465	1.8641	1.4173	0.416	0.0395
open field	percentage of total time in corners, slope, 20 min test	3.5237	1.8686	1.2929	0.499	0.0654
open field	permanence time in center of arena, 20 min test	78.577	35.879	1.2478	0.234	0.0335
open field	permanence time in corners of arena, 20 min test	-101.91	32.019	-1.2507	0.0536	0.00259
open field	permanence time in periphery of arena, 20 min test	-78.572	35.879	-1.2478	0.234	0.0335
open field	total distance traveled, 20 min test	643.80	187.80	1.2106	0.0142	0.00127
open field	total number of rears, 20 min test	30.192	10.272	1.5685	0.0485	0.00509
open field	whole arena average speed, 20 min test	0.53724	0.15651	1.2191	0.0141	0.00126
open field	whole arena resting time, 20 min test	-38.225	21.007	-0.51533	0.217	0.0750
open field	whole arena time spent mobile, 20 min test	8.7858	3.8928	-0.13670	0.111	0.0286
open field	whole arena time spent vertical, 20 min test	26.880	6.7938	1.7676	0.00933	0.000250
startle / PPI	average baseline movement during background noise	5.0363	1.9676	2.2656	0.390	0.0142
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	0.69144	0.79563	2.3454	0.724	0.390
startle / PPI	average of each corrected percent pre-pulse inhibition value	-0.75800	0.32724	-2.8425	0.229	0.0255
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.15010	11.799	0.065199	0.995	0.990
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-17.701	10.969	-1.7543	0.460	0.114
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-54.969	7.5881	-2.9333	0.00000583	6.52e-9
startle / PPI	average startle response to full pulse (120 dB)	-228.09	38.560	-2.7709	0.0000523	5.71e-7
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-219.19	37.891	-2.7110	0.0000579	8.10e-7
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-158.51	34.004	-2.2842	0.00109	0.0000331
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-112.77	25.691	-2.0995	0.00224	0.0000751
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	5.9627	2.1466	2.3240	0.363	0.00822
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	2.7017	1.2470	1.3797	0.447	0.0360
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	3.2801	2.2441	1.1174	0.591	0.151
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.19847	0.43695	-1.6528	0.927	0.652
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.77739	0.43342	-2.8425	0.374	0.0801
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-1.3529	0.37500	-3.0568	0.0194	0.000815
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	-234.04	38.386	-2.7709	0.0000313	3.15e-7
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	-221.16	38.954	-2.7709	0.0000855	0.00000124
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	-161.37	34.279	-2.3240	0.000964	0.0000286
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	-114.51	26.072	-2.0995	0.00238	0.0000745
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	1.8555	1.1746	3.0570	0.775	0.122
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.37209	0.77949	2.1824	0.839	0.636
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-0.22171	0.53512	-1.7101	0.853	0.681
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	-844.97	141.98	-2.7709	0.0000477	5.07e-7
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	-792.41	142.95	-2.6595	0.000104	0.00000193
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	-573.03	128.08	-2.3454	0.00155	0.0000598
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	-421.33	97.165	-2.0870	0.00234	0.0000888
startle / PPI	maximum baseline movement during background noise	11.493	4.5696	2.1826	0.363	0.0158
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	2.8704	12.635	0.32288	0.979	0.821
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-19.408	11.600	-1.7675	0.431	0.102
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-53.462	8.4506	-2.9333	0.000120	1.35e-7
startle / PPI	maximum startle response to full pulse (120 dB)	-831.76	142.77	-2.7110	0.0000720	7.65e-7
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-774.36	143.39	-2.6142	0.000153	0.00000307
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-568.13	127.61	-2.3240	0.00168	0.0000641
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-414.14	96.675	-2.1124	0.00264	0.000105
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	16.526	5.6443	2.4725	0.291	0.00549
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	5.0614	3.0845	1.1769	0.596	0.108
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	10.458	6.4329	1.3582	0.493	0.112

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

In this plot, data points are the computed genotype effect % vs. C57BL/6NJ controls, for all measured categorical phenotypes in JaxKOMP-EAP

Dimensions Width: × Height: px

Plot Options Group by Procedure

Include Sexes Data Both Females Males

Significance Threshold p-Value Threshold

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Procedure	JaxKOMP-EAP Trait	Sex	Trait Effect	P-value

eye morphology	anterior chamber depth	females	1.0 %	1.0
eye morphology	anterior chamber depth	males	0.0 %	1.0
eye morphology	anterior chamber depth	both	1.0 %	1.0
eye morphology	bulging eye	females	1.0 %	1.0
eye morphology	bulging eye	males	0.0 %	1.0
eye morphology	bulging eye	both	1.0 %	1.00
eye morphology	cornea	females	4.0 %	1.0
eye morphology	cornea	males	2.0 %	1.0
eye morphology	cornea	both	3.0 %	1.00
eye morphology	cornea opacity	females	5.0 %	1.00
eye morphology	cornea opacity	males	1.0 %	1.0
eye morphology	cornea opacity	both	3.0 %	1.0
eye morphology	cornea vascularization	females	3.0 %	1.0
eye morphology	cornea vascularization	males	1.0 %	1.0
eye morphology	cornea vascularization	both	2.0 %	1.0
eye morphology	corneal deposits	females	2.0 %	1.0
eye morphology	corneal deposits	males	1.0 %	1.0
eye morphology	corneal deposits	both	1.0 %	1.00
eye morphology	corneal mineralization	females	2.0 %	1.0
eye morphology	corneal mineralization	males	1.0 %	1.0
eye morphology	corneal mineralization	both	1.0 %	1.0
eye morphology	corneal scleralization	females	3.0 %	1.00
eye morphology	corneal scleralization	males	1.0 %	1.0
eye morphology	corneal scleralization	both	2.0 %	1.0
eye morphology	corneal ulcer	females	1.0 %	1.0
eye morphology	corneal ulcer	males	1.0 %	1.0
eye morphology	corneal ulcer	both	1.0 %	1.0
eye morphology	eye closure	females	1.0 %	1.00
eye morphology	eye closure	males	0.0 %	1.0
eye morphology	eye closure	both	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	females	2.0 %	1.00
eye morphology	eye hemorrhage or blood presence	males	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	both	1.0 %	1.0
eye morphology	eyelid morphology	females	1.0 %	1.0
eye morphology	eyelid morphology	males	0.0 %	1.0
eye morphology	eyelid morphology	both	1.0 %	1.0
eye morphology	eyes (present, absent)	females	1.0 %	1.0
eye morphology	eyes (present, absent)	males	0.0 %	1.0
eye morphology	eyes (present, absent)	both	0.0 %	1.0
eye morphology	fusion between cornea and lens	females	4.0 %	1.00
eye morphology	fusion between cornea and lens	males	2.0 %	1.0
eye morphology	fusion between cornea and lens	both	3.0 %	1.0
eye morphology	iris pigmentation	females	2.0 %	1.0
eye morphology	iris pigmentation	males	1.0 %	1.0
eye morphology	iris pigmentation	both	2.0 %	1.0
eye morphology	iris transillumination	females	2.0 %	1.00
eye morphology	iris transillumination	males	1.0 %	1.00
eye morphology	iris transillumination	both	1.0 %	1.00
eye morphology	irispupil	females	4.0 %	1.00
eye morphology	irispupil	males	13.0 %	0.198
eye morphology	irispupil	both	5.0 %	0.415
eye morphology	lacrimation	females	3.0 %	1.0
eye morphology	lacrimation	males	2.0 %	1.0
eye morphology	lacrimation	both	3.0 %	1.0
eye morphology	lens	females	10.0 %	1.00
eye morphology	lens	males	8.0 %	1.00
eye morphology	lens	both	9.0 %	1.0
eye morphology	lens opacity	females	11.0 %	0.316
eye morphology	lens opacity	males	6.0 %	1.00
eye morphology	lens opacity	both	5.0 %	0.441
eye morphology	narrow eye opening	females	2.0 %	1.0
eye morphology	narrow eye opening	males	1.0 %	1.0
eye morphology	narrow eye opening	both	1.0 %	1.00
eye morphology	optic disc	females	4.0 %	1.00
eye morphology	optic disc	males	2.0 %	1.00
eye morphology	optic disc	both	3.0 %	1.00
eye morphology	persistence of hyaloid vascular system	females	14.0 %	1.0
eye morphology	persistence of hyaloid vascular system	males	5.0 %	1.0
eye morphology	persistence of hyaloid vascular system	both	9.0 %	1.00
eye morphology	pupil dilation	females	2.0 %	1.0
eye morphology	pupil dilation	males	1.0 %	1.00
eye morphology	pupil dilation	both	2.0 %	1.0
eye morphology	pupil light response	females	2.0 %	1.00
eye morphology	pupil light response	males	1.0 %	1.0
eye morphology	pupil light response	both	2.0 %	1.0
eye morphology	pupil position	females	4.0 %	1.00
eye morphology	pupil position	males	13.0 %	0.205
eye morphology	pupil position	both	5.0 %	0.440
eye morphology	pupil shape	females	3.0 %	1.00
eye morphology	pupil shape	males	2.0 %	1.0
eye morphology	pupil shape	both	3.0 %	1.0
eye morphology	retina	females	10.0 %	1.0
eye morphology	retina	males	8.0 %	0.703
eye morphology	retina	both	6.0 %	0.872
eye morphology	retinal blood vessels	females	4.0 %	1.0
eye morphology	retinal blood vessels	males	2.0 %	1.0
eye morphology	retinal blood vessels	both	3.0 %	1.0
eye morphology	retinal blood vessels pattern	females	5.0 %	1.0
eye morphology	retinal blood vessels pattern	males	2.0 %	1.00
eye morphology	retinal blood vessels pattern	both	4.0 %	1.00
eye morphology	retinal blood vessels structure	females	4.0 %	1.00
eye morphology	retinal blood vessels structure	males	2.0 %	1.0
eye morphology	retinal blood vessels structure	both	3.0 %	1.0
eye morphology	retinal pigmentation	females	12.0 %	1.0
eye morphology	retinal pigmentation	males	14.0 %	1.0
eye morphology	retinal pigmentation	both	13.0 %	1.0
eye morphology	retinal structure	females	4.0 %	1.00
eye morphology	retinal structure	males	2.0 %	1.00
eye morphology	retinal structure	both	3.0 %	1.00
eye morphology	synechia	females	4.0 %	1.0
eye morphology	synechia	males	2.0 %	1.00
eye morphology	synechia	both	3.0 %	1.00
eye morphology	vitreous	females	4.0 %	1.00
eye morphology	vitreous	males	2.0 %	1.0
eye morphology	vitreous	both	3.0 %	1.0
SHIRPA	activity body position	males	2.0 %	1.0
SHIRPA	activity body position	both	1.0 %	1.0
SHIRPA	aggression	males	1.0 %	1.0
SHIRPA	aggression	both	1.0 %	1.00
SHIRPA	body length	males	0.0 %	1.0
SHIRPA	body length	both	0.0 %	1.0
SHIRPA	body position	males	1.0 %	1.0
SHIRPA	body position	both	0.0 %	1.0
SHIRPA	body thickness	males	0.0 %	1.0
SHIRPA	body thickness	both	0.0 %	1.0
SHIRPA	coat color abdomen	males	4.0 %	1.00
SHIRPA	coat color abdomen	both	4.0 %	1.0
SHIRPA	coat color back	males	0.0 %	1.0
SHIRPA	coat color back	both	0.0 %	1.0
SHIRPA	coat color head	males	0.0 %	1.0
SHIRPA	coat color head	both	0.0 %	1.0
SHIRPA	coat color pattern abdomen	males	1.0 %	1.0
SHIRPA	coat color pattern abdomen	both	1.0 %	1.0
SHIRPA	coat color pattern back	males	0.0 %	1.0
SHIRPA	coat color pattern back	both	0.0 %	1.0
SHIRPA	coat color pattern head	males	0.0 %	1.00
SHIRPA	coat color pattern head	both	0.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	males	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	both	2.0 %	1.0
SHIRPA	coat hair back texture appearance	males	0.0 %	1.0
SHIRPA	coat hair back texture appearance	both	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	males	1.0 %	1.0
SHIRPA	coat hair distribution abdomen	both	1.0 %	1.0
SHIRPA	coat hair distribution back	males	0.0 %	1.0
SHIRPA	coat hair distribution back	both	0.0 %	1.0
SHIRPA	coat hair distribution head	males	1.0 %	1.0
SHIRPA	coat hair distribution head	both	1.0 %	1.0
SHIRPA	coat hair head texture appearance	males	0.0 %	1.0
SHIRPA	coat hair head texture appearance	both	0.0 %	1.0
SHIRPA	contact righting	males	5.0 %	1.00
SHIRPA	contact righting	both	5.0 %	1.0
SHIRPA	ear morphology	males	29.0 %	0.00000577
SHIRPA	ear morphology	both	29.0 %	0.00000143
SHIRPA	fat distribution	males	0.0 %	1.0
SHIRPA	fat distribution	both	0.0 %	1.0
SHIRPA	forelimb digit number	males	0.0 %	1.0
SHIRPA	forelimb digit number	both	0.0 %	1.0
SHIRPA	forelimb digit position	males	0.0 %	1.0
SHIRPA	forelimb digit position	both	0.0 %	1.0
SHIRPA	forelimb digit shape	males	0.0 %	1.0
SHIRPA	forelimb digit shape	both	0.0 %	1.0
SHIRPA	forelimb digit size	males	0.0 %	1.0
SHIRPA	forelimb digit size	both	0.0 %	1.0
SHIRPA	forelimb footpads	males	0.0 %	1.0
SHIRPA	forelimb footpads	both	0.0 %	1.0
SHIRPA	forelimb nail length	males	0.0 %	1.0
SHIRPA	forelimb nail length	both	0.0 %	1.0
SHIRPA	forelimb nail number	males	0.0 %	1.0
SHIRPA	forelimb nail number	both	0.0 %	1.0
SHIRPA	forelimb nail position	males	0.0 %	1.0
SHIRPA	forelimb nail position	both	0.0 %	1.0
SHIRPA	forelimb nail shape	males	0.0 %	1.0
SHIRPA	forelimb nail shape	both	0.0 %	1.0
SHIRPA	forelimbs position	males	0.0 %	1.0
SHIRPA	forelimbs position	both	0.0 %	1.0
SHIRPA	forelimbs shape	males	0.0 %	1.0
SHIRPA	forelimbs shape	both	0.0 %	1.0
SHIRPA	forelimbs size	males	0.0 %	1.00
SHIRPA	forelimbs size	both	0.0 %	1.0
SHIRPA	forepaw position	males	0.0 %	1.0
SHIRPA	forepaw position	both	0.0 %	1.0
SHIRPA	forepaw shape	males	0.0 %	1.0
SHIRPA	forepaw shape	both	0.0 %	1.0
SHIRPA	forepaw size	males	0.0 %	1.0
SHIRPA	forepaw size	both	0.0 %	1.0
SHIRPA	gait (fluidity)	males	0.0 %	1.0
SHIRPA	gait (fluidity)	both	0.0 %	1.0
SHIRPA	genitalia morphology	males	0.0 %	1.0
SHIRPA	genitalia morphology	both	0.0 %	1.0
SHIRPA	genitalia presence	males	0.0 %	1.0
SHIRPA	genitalia presence	both	0.0 %	1.0
SHIRPA	genitalia size	males	0.0 %	1.00
SHIRPA	genitalia size	both	0.0 %	1.0
SHIRPA	head bobbing	males	29.0 %	0.0000173
SHIRPA	head bobbing	both	29.0 %	0.00000430
SHIRPA	head morphology	males	0.0 %	1.0
SHIRPA	head morphology	both	0.0 %	1.0
SHIRPA	head size	males	0.0 %	1.00
SHIRPA	head size	both	0.0 %	1.0
SHIRPA	hindlimb digit number	males	0.0 %	1.0
SHIRPA	hindlimb digit number	both	0.0 %	1.0
SHIRPA	hindlimb digit position	males	0.0 %	1.0
SHIRPA	hindlimb digit position	both	0.0 %	1.0
SHIRPA	hindlimb digit shape	males	0.0 %	1.0
SHIRPA	hindlimb digit shape	both	0.0 %	1.0
SHIRPA	hindlimb digit size	males	0.0 %	1.00
SHIRPA	hindlimb digit size	both	0.0 %	1.0
SHIRPA	hindlimb nail length	males	0.0 %	1.00
SHIRPA	hindlimb nail length	both	0.0 %	1.0
SHIRPA	hindlimb nail number	males	1.0 %	1.00
SHIRPA	hindlimb nail number	both	0.0 %	1.0
SHIRPA	hindlimb nail position	males	0.0 %	1.0
SHIRPA	hindlimb nail position	both	0.0 %	1.0
SHIRPA	hindlimb nail shape	males	0.0 %	1.0
SHIRPA	hindlimb nail shape	both	0.0 %	1.0
SHIRPA	hindlimbs footpads	males	0.0 %	1.0
SHIRPA	hindlimbs footpads	both	0.0 %	1.0
SHIRPA	hindlimbs position	males	0.0 %	1.0
SHIRPA	hindlimbs position	both	0.0 %	1.0
SHIRPA	hindlimbs shape	males	0.0 %	1.0
SHIRPA	hindlimbs shape	both	0.0 %	1.0
SHIRPA	hindlimbs size	males	0.0 %	1.0
SHIRPA	hindlimbs size	both	0.0 %	1.0
SHIRPA	hindpaw position	males	0.0 %	1.0
SHIRPA	hindpaw position	both	0.0 %	1.0
SHIRPA	hindpaw shape	males	0.0 %	1.0
SHIRPA	hindpaw shape	both	0.0 %	1.0
SHIRPA	hindpaw size	males	0.0 %	1.0
SHIRPA	hindpaw size	both	0.0 %	1.0
SHIRPA	limb grasp	males	6.0 %	1.0
SHIRPA	limb grasp	both	7.0 %	1.00
SHIRPA	lower lip morphology	males	0.0 %	1.0
SHIRPA	lower lip morphology	both	0.0 %	1.0
SHIRPA	lower teeth appearance	males	0.0 %	1.0
SHIRPA	lower teeth appearance	both	0.0 %	1.0
SHIRPA	mouth morphology	males	0.0 %	1.0
SHIRPA	mouth morphology	both	0.0 %	1.0
SHIRPA	salivation	males	0.0 %	1.0
SHIRPA	salivation	both	0.0 %	1.0
SHIRPA	skin color back paws	males	0.0 %	1.0
SHIRPA	skin color back paws	both	0.0 %	1.0
SHIRPA	skin color ear	males	0.0 %	1.0
SHIRPA	skin color ear	both	0.0 %	1.0
SHIRPA	skin color front paws	males	0.0 %	1.0
SHIRPA	skin color front paws	both	0.0 %	1.0
SHIRPA	skin color snout	males	0.0 %	1.0
SHIRPA	skin color snout	both	0.0 %	1.0
SHIRPA	skin color tail	males	0.0 %	1.0
SHIRPA	skin color tail	both	0.0 %	1.0
SHIRPA	skin color whole body	males	0.0 %	1.0
SHIRPA	skin color whole body	both	0.0 %	1.0
SHIRPA	skin texture back paw	males	0.0 %	1.0
SHIRPA	skin texture back paw	both	0.0 %	1.0
SHIRPA	skin texture ear	males	0.0 %	1.0
SHIRPA	skin texture ear	both	0.0 %	1.0
SHIRPA	skin texture front paws	males	0.0 %	1.0
SHIRPA	skin texture front paws	both	0.0 %	1.0
SHIRPA	skin texture snout	males	0.0 %	1.0
SHIRPA	skin texture snout	both	0.0 %	1.0
SHIRPA	skin texture tail	males	0.0 %	1.0
SHIRPA	skin texture tail	both	0.0 %	1.0
SHIRPA	skin texture whole body	males	0.0 %	1.0
SHIRPA	skin texture whole body	both	0.0 %	1.0
SHIRPA	snout size	males	1.0 %	1.0
SHIRPA	snout size	both	0.0 %	1.0
SHIRPA	startle response	males	28.0 %	0.000206
SHIRPA	startle response	both	28.0 %	0.000111
SHIRPA	tail curvature	males	0.0 %	1.0
SHIRPA	tail curvature	both	0.0 %	1.0
SHIRPA	tail elevation	males	2.0 %	1.0
SHIRPA	tail elevation	both	1.0 %	1.0
SHIRPA	tail length	males	0.0 %	1.00
SHIRPA	tail length	both	0.0 %	1.0
SHIRPA	tail morphology	males	0.0 %	1.00
SHIRPA	tail morphology	both	0.0 %	1.0
SHIRPA	tail presence	males	0.0 %	1.0
SHIRPA	tail presence	both	0.0 %	1.0
SHIRPA	tail shape	males	0.0 %	1.0
SHIRPA	tail shape	both	0.0 %	1.0
SHIRPA	tail thickness	males	0.0 %	1.0
SHIRPA	tail thickness	both	0.0 %	1.0
SHIRPA	teeth presence	males	0.0 %	1.0
SHIRPA	teeth presence	both	0.0 %	1.0
SHIRPA	transfer arousal	males	13.0 %	0.113
SHIRPA	transfer arousal	both	14.0 %	0.0942
SHIRPA	tremor	males	0.0 %	1.0
SHIRPA	tremor	both	0.0 %	1.0
SHIRPA	trunk curl	males	0.0 %	1.0
SHIRPA	trunk curl	both	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	males	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	both	0.0 %	1.0
SHIRPA	upper lip morphology	males	0.0 %	1.0
SHIRPA	upper lip morphology	both	0.0 %	1.0
SHIRPA	upper teeth appearance	males	0.0 %	1.00
SHIRPA	upper teeth appearance	both	0.0 %	1.0
SHIRPA	vibrissae appearance	males	1.0 %	1.0
SHIRPA	vibrissae appearance	both	1.0 %	1.0
SHIRPA	vibrissae presence	males	1.0 %	1.0
SHIRPA	vibrissae presence	both	2.0 %	1.0
SHIRPA	vocalization	males	2.0 %	1.0
SHIRPA	vocalization	both	2.0 %	1.0

GENOTYPE CORRELATION PLOT

Correlate Grxcr1^em1(IMPC)J/Mmjax -/- with genotype:

This genotype correlation visualization can include both EAP and LAP measures.