MPD: JaxKOMP-EAP genotype: Fam43a<sup>em1(IMPC)J</sup>/Mmjax -/-

JaxKOMP-EAP effect sizes: Fam43a^em1(IMPC)J/Mmjax -/- Gene Fam43a

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

In this plot, data points are the computed genotype effect size vs. C57BL/6NJ controls, for all measured numeric phenotypes in JaxKOMP-EAP

Dimensions Width: × Height: px

Plot Options Group by Procedure Standard Error Show Effect Sizes RankZ

Significance Threshold p-Value Threshold Adjusted Unadjusted

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Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value

ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	-2.2727	2.5813	-0.88768	0.795	0.397
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	3.4091	5.3638	0.74420	0.859	0.538
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	-4.2045	5.0701	-1.0358	0.758	0.425
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	1.0193	3.1745	0.038714	0.909	0.754
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	-7.3740	5.2450	-1.0711	0.572	0.187
clinical blood chemistry	alanine transaminase (plasma ALT)	-20.884	19.744	-1.5185	0.670	0.302
clinical blood chemistry	albumin (plasma Alb)	-0.15344	0.34520	-0.17339	0.866	0.661
clinical blood chemistry	alkaline phosphatase (plasma ALP)	-5.1378	2.6684	-1.3772	0.232	0.0678
clinical blood chemistry	aspartate transaminase (plasma AST)	0.88413	15.898	0.048223	0.985	0.956
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	0.68699	0.24874	1.6922	0.185	0.0114
clinical blood chemistry	blood urea nitrogen (BUN)	1.2536	1.5294	0.46559	0.679	0.421
clinical blood chemistry	calcium (plasma Ca)	-0.32523	0.064106	-1.8476	0.00221	0.0000504
clinical blood chemistry	creatinine (plasma)	0.014716	0.014371	0.45779	0.562	0.317
clinical blood chemistry	glucose (plasma GLU, no fast)	-23.200	11.446	-0.57339	0.168	0.0550
clinical blood chemistry	HDL cholesterol (plasma HDL)	4.7134	3.1580	0.77063	0.423	0.150
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	-0.0038676	0.0091595	-0.39200	0.889	0.677
clinical blood chemistry	phosphorus (plasma phosphate)	0.13827	0.44054	0.17691	0.888	0.757
clinical blood chemistry	total bilirubin (plasma TBIL)	0.00059567	0.0073578	0.053963	0.982	0.936
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	7.3989	4.0603	0.99232	0.308	0.0820
clinical blood chemistry	total protein (plasma TP)	-0.25870	0.55407	-0.26575	0.815	0.645
clinical blood chemistry	triglyceride (plasma TG, no fast)	57.280	34.683	2.2224	0.367	0.113
ERG v2.0	left eye a-wave amplitude (Photopic)	5.5546	4.0043	1.7317	0.672	0.300
ERG v2.0	left eye a-wave amplitude (Scotopic)	60.908	25.252	1.8098	0.491	0.137
ERG v2.0	left eye a-wave implicit timing (Photopic)	-0.44631	2.3857	-0.074441	0.989	0.869
ERG v2.0	left eye a-wave implicit timing (Scotopic)	0.38323	0.69804	0.35940	0.869	0.638
ERG v2.0	left eye b-wave amplitude (Photopic)	-16.573	12.342	-1.4910	0.736	0.311
ERG v2.0	left eye b-wave amplitude (Scotopic)	-114.84	53.179	-1.4572	0.572	0.163
ERG v2.0	left eye b-wave implicit timing (Photopic)	-7.6367	6.0996	-1.5079	0.676	0.337
ERG v2.0	left eye b-wave implicit timing (Scotopic)	-14.159	20.712	-1.2753	0.835	0.565
ERG v2.0	left eye c-wave amplitude (Scotopic)	-61.199	45.847	-0.95868	0.699	0.314
ERG v2.0	left eye c-wave implicit timing (Scotopic)	-134.19	91.910	-1.3413	0.682	0.282
ERG v2.0	left eye FO-like wave amplitude (Scotopic)	93.542	34.381	1.1293	0.504	0.113
ERG v2.0	left eye FO-like wave implicit timing (Scotopic)	679.95	561.89	2.0583	0.838	0.350
ERG v2.0	right eye a-wave amplitude (Photopic)	0.62017	5.9746	0.27840	0.990	0.927
ERG v2.0	right eye a-wave amplitude (Scotopic)	88.644	40.206	2.2916	0.605	0.158
ERG v2.0	right eye a-wave implicit timing (Photopic)	-0.96455	2.5505	-0.46524	0.941	0.742
ERG v2.0	right eye a-wave implicit timing (Scotopic)	0.94133	1.0462	0.81671	0.813	0.463
ERG v2.0	right eye b-wave amplitude (Photopic)	-20.332	9.0889	-1.7076	0.587	0.155
ERG v2.0	right eye b-wave amplitude (Scotopic)	-159.80	111.83	-2.0154	0.762	0.289
ERG v2.0	right eye b-wave implicit timing (Photopic)	-2.4771	1.2833	-0.38888	0.581	0.193
ERG v2.0	right eye b-wave implicit timing (Scotopic)	-2.6538	5.9823	-0.11569	0.909	0.701
ERG v2.0	right eye c-wave amplitude (Scotopic)	-63.710	73.557	-1.1190	0.839	0.478
ERG v2.0	right eye c-wave implicit timing (Scotopic)	-129.24	57.721	-1.2630	0.731	0.155
ERG v2.0	right eye FO-like wave amplitude (Scotopic)	78.536	91.483	0.95001	0.820	0.481
ERG v2.0	right eye FO-like wave implicit timing (Scotopic)	-280.87	623.32	-0.89943	0.924	0.696
glucose tolerance test	amount glucose injected	1.3139	3.4274	0.74299	0.908	0.704
glucose tolerance test	plasma glucose, 0min	8.0000	5.7545	0.59637	0.372	0.173
glucose tolerance test	plasma glucose, 15min	-17.567	13.082	-0.37367	0.505	0.188
glucose tolerance test	plasma glucose, 30min	-6.0420	14.715	-0.050813	0.867	0.684
glucose tolerance test	plasma glucose, 60min	9.1298	16.227	0.48974	0.828	0.577
glucose tolerance test	plasma glucose, 120min	7.5767	10.601	0.36925	0.742	0.480
grip strength	body weight (at time of grip strength test)	-0.38510	0.35923	-0.15878	0.488	0.294
grip strength	forelimb and hindlimb grip strength (mean of trials), average	-2.0042	5.0151	0.097457	0.834	0.693
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	-0.087781	0.27918	0.077047	0.860	0.756
grip strength	forelimb and hindlimb grip strength by trial, trial1	-7.5601	8.1774	-0.27199	0.660	0.364
grip strength	forelimb and hindlimb grip strength by trial, trial2	-3.3382	7.0769	0.015976	0.827	0.641
grip strength	forelimb and hindlimb grip strength by trial, trial3	5.4272	6.3262	0.56109	0.661	0.399
grip strength	forelimb grip strength (mean of trials), average	0.41374	3.5805	0.33741	0.968	0.909
grip strength	forelimb grip strength (mean of trials), average normalized to bw	-0.010550	0.17124	0.20474	0.981	0.951
grip strength	forelimb grip strength by trial, trial1	8.1078	4.8442	1.1929	0.383	0.106
grip strength	forelimb grip strength by trial, trial2	-4.3957	4.5675	-0.27802	0.669	0.345
grip strength	forelimb grip strength by trial, trial3	-2.8673	4.6873	-0.061033	0.790	0.546
heart weight	heart weight, normalized to body weight	0.016149	0.12036	-0.39443	0.947	0.894
heart weight	heart weight, weight	1.1538	3.8396	-0.21584	0.871	0.766
hematology	basophil differential (percent of total WBC)	-0.089453	0.15903	-1.1891	0.855	0.579
hematology	eosinophil differential (percent of total WBC)	0.26988	0.23648	0.82152	0.647	0.266
hematology	hematocrit (HCT)	1.0114	0.52145	0.80102	0.300	0.0648
hematology	lymphocyte differential (percent of total WBC)	0.23399	1.6718	0.054697	0.952	0.890
hematology	mean corpuscular hemoglobin (CHr)	-0.10703	0.063654	-0.85470	0.294	0.106
hematology	mean platelet volume (MPV)	0.066947	0.038482	0.26583	0.257	0.0953
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	-0.24803	0.098873	-0.51343	0.192	0.0200
hematology	mean RBC corpuscular volume (MCV)	0.023557	0.19677	0.056066	0.958	0.906
hematology	measured hemoglobin (mHGB)	0.17305	0.17006	0.19333	0.619	0.319
hematology	monocyte differential (percent of total WBC)	-0.49297	0.33859	-1.0970	0.518	0.159
hematology	neutrophil differential (percent of total WBC)	-0.022140	1.1214	0.010934	0.994	0.984
hematology	platelet count (PLT; units per volume x 10³)	54.621	57.929	0.76756	0.693	0.356
hematology	RBC corpuscular distribution width (RDW)	-0.30063	0.18216	-1.1181	0.342	0.112
hematology	red blood cell count (RBC; per volume x 10⁶)	0.16570	0.13807	0.40188	0.511	0.242
hematology	reticulocyte count (Retic; units per volume x 10⁹)	62.136	15.943	1.9951	0.0399	0.000726
hematology	reticulocyte differential (percent of total RBC)	0.52324	0.15417	1.7939	0.107	0.00249
hematology	white blood cell count (WBC; units per volume x 10³)	-2.4594	1.1517	-1.3860	0.152	0.0441
holeboard	number of hole pokes by individual hole number, 20 min test, 1	-1.8064	0.94197	-1.6665	0.485	0.0666
holeboard	number of hole pokes by individual hole number, 20 min test, 2	-0.20420	0.69221	-0.17389	0.953	0.771
holeboard	number of hole pokes by individual hole number, 20 min test, 3	-0.73221	0.61219	-1.1557	0.745	0.243
holeboard	number of hole pokes by individual hole number, 20 min test, 4	-0.22341	1.0648	-0.11758	0.953	0.836
holeboard	number of hole pokes by individual hole number, 20 min test, 5	-0.85385	0.80390	-1.2912	0.773	0.298
holeboard	number of hole pokes by individual hole number, 20 min test, 6	-0.22308	0.41972	-0.61734	0.930	0.600
holeboard	number of hole pokes by individual hole number, 20 min test, 7	0.54615	0.36391	1.3553	0.737	0.146
holeboard	number of hole pokes by individual hole number, 20 min test, 8	-0.046154	0.52826	0.056577	0.987	0.931
holeboard	number of hole pokes by individual hole number, 20 min test, 9	-0.65764	0.44678	-1.0295	0.620	0.154
holeboard	number of hole pokes by individual hole number, 20 min test, 10	0.46154	0.38242	1.1446	0.788	0.239
holeboard	number of hole pokes by individual hole number, 20 min test, 11	0.40292	0.43496	0.94960	0.836	0.363
holeboard	number of hole pokes by individual hole number, 20 min test, 12	-0.86154	1.0052	-1.2877	0.801	0.400
holeboard	number of hole pokes by individual hole number, 20 min test, 13	0.59231	0.84256	0.68192	0.815	0.489
holeboard	number of hole pokes by individual hole number, 20 min test, 14	1.1615	0.72986	1.7235	0.563	0.124
holeboard	number of hole pokes by individual hole number, 20 min test, 15	-0.60943	0.61820	-0.87874	0.772	0.334
holeboard	number of hole pokes by individual hole number, 20 min test, 16	0.13775	1.0440	0.14899	0.963	0.896
holeboard	total number of hole pokes, 20 min test	-3.1077	5.0140	-0.32975	0.763	0.541
light / dark	latency to enter dark zone, 20 min test	-33.993	34.570	-0.74851	0.727	0.335
light / dark	number of transitions between light and dark zones, 20 min test	-10.924	4.8052	-1.0070	0.214	0.0315
light / dark	percentage of total time in dark zone, 20 min test	-1.2819	5.7323	-0.10701	0.943	0.825
light / dark	percentage of total time in light zone, 20 min test	1.2819	5.7323	0.10429	0.944	0.825
light / dark	time mobile in dark zone, 20 min test	-1.1913	5.4861	-0.17668	0.933	0.830
light / dark	time mobile in light zone, 20 min test	-2.8070	5.1347	-0.44860	0.801	0.589
light / dark	time spent in dark zone, 20 min test	22.514	64.270	0.54029	0.920	0.729
light / dark	time spent in light zone, 20 min test	-22.514	64.270	-0.54029	0.920	0.729
open field	average speed in center of arena, 20 min test	0.65913	0.32163	1.0183	0.297	0.0478
open field	average speed in periphery of arena, 20 min test	0.16656	0.11080	0.14483	0.331	0.141
open field	distance traveled habituation ratio, 20 min test	-6.4808	6.0661	-0.52610	0.616	0.292
open field	distance traveled in center of arena, 20 min test	75.461	80.130	0.14076	0.609	0.353
open field	distance traveled in periphery of arena, 20 min test	190.76	125.36	0.32164	0.345	0.137
open field	distance traveled slope, 20 min test	-9.8817	5.7597	-0.87146	0.367	0.0948
open field	distance traveled, 20 min test, 1st 5min	91.071	48.016	0.39612	0.227	0.0659
open field	distance traveled, 20 min test, 2nd 5min	141.08	41.158	1.0320	0.0194	0.00154
open field	distance traveled, 20 min test, 3rd 5min	15.203	48.683	-0.24199	0.891	0.757
open field	distance traveled, 20 min test, 4th 5min	25.195	49.117	-0.16113	0.795	0.611
open field	number of clockwise revolution episodes, 20 min test	0.63412	0.96669	-0.033589	0.800	0.516
open field	number of counter-clockwise revolution episodes, 20 min test	2.5352	1.2188	0.91141	0.228	0.0447
open field	number of rears in 5 min bins, 20 min test, 1st 5min	-0.30037	2.2538	-0.28735	0.953	0.895
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	2.4405	3.7636	0.27950	0.751	0.521
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	-0.55521	3.9148	-0.42827	0.948	0.888
open field	number of rears in 5 min bins, 20 min test, 4th 5min	1.6913	3.6015	0.030213	0.820	0.641
open field	percentage of total time in center of arena, 20 min test	-1.2965	2.3074	-0.52455	0.834	0.578
open field	percentage of total time in center of arena, slope, 20 min test	-1.1233	1.7451	-0.49095	0.867	0.524
open field	percentage of total time in center, habituation ratio, 20 min test	-0.91486	1.8914	-0.35005	0.897	0.632
open field	percentage of total time in corners of arena, 20 min test	-1.5487	2.8334	0.014098	0.822	0.588
open field	percentage of total time in corners, habituation ratio, 20 min test	2.8852	2.0518	0.98073	0.649	0.168
open field	percentage of total time in corners, slope, 20 min test	2.9852	1.9705	1.0740	0.629	0.139
open field	permanence time in center of arena, 20 min test	-15.545	27.690	-0.52455	0.834	0.578
open field	permanence time in corners of arena, 20 min test	-18.587	34.002	0.014098	0.823	0.588
open field	permanence time in periphery of arena, 20 min test	15.544	27.690	0.52455	0.834	0.578
open field	total distance traveled, 20 min test	279.37	155.28	0.30894	0.224	0.0804
open field	total number of rears, 20 min test	2.7577	11.863	-0.14212	0.918	0.817
open field	whole arena average speed, 20 min test	0.23437	0.12918	0.31599	0.220	0.0780
open field	whole arena resting time, 20 min test	-78.589	21.818	-1.3781	0.00989	0.000970
open field	whole arena time spent mobile, 20 min test	14.255	3.8234	0.090750	0.00748	0.000661
open field	whole arena time spent vertical, 20 min test	-3.2912	7.0880	-0.38742	0.858	0.645
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	-1.2845	1.5271	-0.35902	0.689	0.408
startle / PPI	average baseline movement during background noise	0.56557	1.6950	0.45442	0.952	0.742
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	-0.056090	0.055823	-0.62134	0.673	0.326
startle / PPI	average of each corrected percent pre-pulse inhibition value	-0.054553	0.059497	-0.63066	0.703	0.370
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	13.884	8.0136	1.6473	0.817	0.0978
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-4.4548	7.3966	-0.47158	0.812	0.553
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-18.925	6.8729	-1.7743	0.120	0.0119
startle / PPI	average startle response to full pulse (120 dB)	289.25	45.656	2.9333	0.000178	0.00000278
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	254.85	44.874	2.6595	0.000500	0.0000123
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	247.37	43.038	2.7709	0.000447	0.0000105
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	228.00	34.493	2.5035	0.000170	0.00000152
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	-0.33634	1.3658	-0.20530	0.973	0.808
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	1.2951	1.5502	0.77140	0.858	0.413
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	0.77934	2.5575	0.20101	0.943	0.764
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.16788	0.096133	1.6638	0.782	0.0954
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.050664	0.086569	-0.50057	0.813	0.565
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-0.27841	0.082647	-2.0510	0.0422	0.00290
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	287.59	46.239	2.9333	0.000203	0.00000360
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	253.43	44.883	2.6595	0.000529	0.0000133
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	245.91	43.620	2.7709	0.000562	0.0000135
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	225.24	35.336	2.5370	0.000199	0.00000255
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.19749	0.12237	1.6866	0.775	0.122
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.074855	0.073708	-0.65005	0.658	0.321
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-0.30130	0.081776	-2.0626	0.0282	0.00138
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	1068.6	165.76	2.9333	0.000160	0.00000218
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	947.18	159.87	2.7709	0.000291	0.00000701
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	926.31	140.65	2.8428	0.000115	0.00000160
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	874.43	117.63	2.7709	0.0000360	2.62e-7
startle / PPI	maximum baseline movement during background noise	1.7077	4.2218	0.57939	0.937	0.690
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	17.284	10.466	1.7811	0.797	0.114
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-6.4463	6.5759	-0.62986	0.686	0.338
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-22.620	7.2975	-1.9118	0.0738	0.00543
startle / PPI	maximum startle response to full pulse (120 dB)	1072.6	164.24	2.9333	0.000145	0.00000181
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	948.95	159.30	2.7709	0.000265	0.00000652
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	927.78	138.41	2.8428	0.0000992	0.00000124
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	879.83	115.34	2.8428	0.0000313	1.75e-7
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	-2.8745	2.8262	-0.79616	0.773	0.321
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	2.9481	3.7294	0.79041	0.827	0.438
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	-0.86612	6.5420	-0.36600	0.977	0.896

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

In this plot, data points are the computed genotype effect % vs. C57BL/6NJ controls, for all measured categorical phenotypes in JaxKOMP-EAP

Dimensions Width: × Height: px

Plot Options Group by Procedure

Include Sexes Data Both Females Males

Significance Threshold p-Value Threshold

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Procedure	JaxKOMP-EAP Trait	Sex	Trait Effect	P-value

eye morphology	anterior chamber depth	females	1.0 %	1.0
eye morphology	anterior chamber depth	males	0.0 %	1.0
eye morphology	anterior chamber depth	both	1.0 %	1.0
eye morphology	bulging eye	females	1.0 %	1.0
eye morphology	bulging eye	males	0.0 %	1.0
eye morphology	bulging eye	both	1.0 %	1.00
eye morphology	cornea	females	4.0 %	1.0
eye morphology	cornea	males	2.0 %	1.0
eye morphology	cornea	both	3.0 %	1.00
eye morphology	cornea opacity	females	5.0 %	1.0
eye morphology	cornea opacity	males	1.0 %	1.0
eye morphology	cornea opacity	both	3.0 %	1.0
eye morphology	cornea vascularization	females	3.0 %	1.0
eye morphology	cornea vascularization	males	1.0 %	1.0
eye morphology	cornea vascularization	both	2.0 %	1.0
eye morphology	corneal deposits	females	2.0 %	1.0
eye morphology	corneal deposits	males	1.0 %	1.0
eye morphology	corneal deposits	both	1.0 %	1.00
eye morphology	corneal mineralization	females	2.0 %	1.0
eye morphology	corneal mineralization	males	1.0 %	1.0
eye morphology	corneal mineralization	both	1.0 %	1.0
eye morphology	corneal scleralization	females	3.0 %	1.0
eye morphology	corneal scleralization	males	1.0 %	1.0
eye morphology	corneal scleralization	both	2.0 %	1.0
eye morphology	corneal ulcer	females	1.0 %	1.0
eye morphology	corneal ulcer	males	1.0 %	1.0
eye morphology	corneal ulcer	both	1.0 %	1.0
eye morphology	eye closure	females	1.0 %	1.0
eye morphology	eye closure	males	0.0 %	1.0
eye morphology	eye closure	both	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	females	2.0 %	1.0
eye morphology	eye hemorrhage or blood presence	males	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	both	1.0 %	1.0
eye morphology	eyelid morphology	females	1.0 %	1.0
eye morphology	eyelid morphology	males	0.0 %	1.0
eye morphology	eyelid morphology	both	1.0 %	1.0
eye morphology	eyes (present, absent)	females	1.0 %	1.0
eye morphology	eyes (present, absent)	males	0.0 %	1.0
eye morphology	eyes (present, absent)	both	0.0 %	1.0
eye morphology	fusion between cornea and lens	females	4.0 %	1.0
eye morphology	fusion between cornea and lens	males	2.0 %	1.0
eye morphology	fusion between cornea and lens	both	3.0 %	1.0
eye morphology	iris pigmentation	females	2.0 %	1.0
eye morphology	iris pigmentation	males	1.0 %	1.0
eye morphology	iris pigmentation	both	2.0 %	1.0
eye morphology	iris transillumination	females	2.0 %	1.0
eye morphology	iris transillumination	males	1.0 %	1.0
eye morphology	iris transillumination	both	1.0 %	1.00
eye morphology	irispupil	females	4.0 %	1.0
eye morphology	irispupil	males	3.0 %	1.0
eye morphology	irispupil	both	3.0 %	1.0
eye morphology	lacrimation	females	3.0 %	1.00
eye morphology	lacrimation	males	2.0 %	1.0
eye morphology	lacrimation	both	3.0 %	1.0
eye morphology	lens	females	10.0 %	1.0
eye morphology	lens	males	8.0 %	1.0
eye morphology	lens	both	9.0 %	1.0
eye morphology	lens opacity	females	9.0 %	1.0
eye morphology	lens opacity	males	6.0 %	1.0
eye morphology	lens opacity	both	7.0 %	1.00
eye morphology	narrow eye opening	females	2.0 %	1.00
eye morphology	narrow eye opening	males	1.0 %	1.0
eye morphology	narrow eye opening	both	1.0 %	1.00
eye morphology	optic disc	females	4.0 %	1.0
eye morphology	optic disc	males	2.0 %	1.0
eye morphology	optic disc	both	3.0 %	1.00
eye morphology	persistence of hyaloid vascular system	females	14.0 %	1.0
eye morphology	persistence of hyaloid vascular system	males	5.0 %	1.0
eye morphology	persistence of hyaloid vascular system	both	9.0 %	1.00
eye morphology	pupil dilation	females	2.0 %	1.0
eye morphology	pupil dilation	males	1.0 %	1.0
eye morphology	pupil dilation	both	2.0 %	1.0
eye morphology	pupil light response	females	2.0 %	1.0
eye morphology	pupil light response	males	1.0 %	1.0
eye morphology	pupil light response	both	2.0 %	1.0
eye morphology	pupil position	females	4.0 %	1.0
eye morphology	pupil position	males	3.0 %	1.0
eye morphology	pupil position	both	4.0 %	1.0
eye morphology	pupil shape	females	3.0 %	1.0
eye morphology	pupil shape	males	2.0 %	1.0
eye morphology	pupil shape	both	3.0 %	1.0
eye morphology	retina	females	10.0 %	1.0
eye morphology	retina	males	20.0 %	0.220
eye morphology	retina	both	9.0 %	0.468
eye morphology	retinal blood vessels	females	4.0 %	1.0
eye morphology	retinal blood vessels	males	2.0 %	1.0
eye morphology	retinal blood vessels	both	3.0 %	1.0
eye morphology	retinal blood vessels pattern	females	5.0 %	1.0
eye morphology	retinal blood vessels pattern	males	2.0 %	1.0
eye morphology	retinal blood vessels pattern	both	4.0 %	1.00
eye morphology	retinal blood vessels structure	females	4.0 %	1.0
eye morphology	retinal blood vessels structure	males	2.0 %	1.0
eye morphology	retinal blood vessels structure	both	3.0 %	1.0
eye morphology	retinal pigmentation	females	12.0 %	1.0
eye morphology	retinal pigmentation	males	14.0 %	1.0
eye morphology	retinal pigmentation	both	13.0 %	1.0
eye morphology	retinal structure	females	4.0 %	1.0
eye morphology	retinal structure	males	2.0 %	1.0
eye morphology	retinal structure	both	3.0 %	1.00
eye morphology	synechia	females	4.0 %	1.0
eye morphology	synechia	males	2.0 %	1.0
eye morphology	synechia	both	3.0 %	1.00
eye morphology	vitreous	females	4.0 %	1.0
eye morphology	vitreous	males	2.0 %	1.0
eye morphology	vitreous	both	3.0 %	1.0
SHIRPA	activity body position	females	1.0 %	1.0
SHIRPA	activity body position	males	2.0 %	1.0
SHIRPA	activity body position	both	1.0 %	1.00
SHIRPA	aggression	females	0.0 %	1.0
SHIRPA	aggression	males	1.0 %	1.0
SHIRPA	aggression	both	1.0 %	1.00
SHIRPA	body length	females	0.0 %	1.0
SHIRPA	body length	males	0.0 %	1.00
SHIRPA	body length	both	0.0 %	1.0
SHIRPA	body position	females	0.0 %	1.0
SHIRPA	body position	males	1.0 %	1.0
SHIRPA	body position	both	0.0 %	1.00
SHIRPA	body thickness	females	1.0 %	1.0
SHIRPA	body thickness	males	0.0 %	1.0
SHIRPA	body thickness	both	0.0 %	1.00
SHIRPA	coat color abdomen	females	3.0 %	1.0
SHIRPA	coat color abdomen	males	4.0 %	1.0
SHIRPA	coat color abdomen	both	4.0 %	1.00
SHIRPA	coat color back	females	0.0 %	1.0
SHIRPA	coat color back	males	0.0 %	1.00
SHIRPA	coat color back	both	0.0 %	1.00
SHIRPA	coat color head	females	0.0 %	1.0
SHIRPA	coat color head	males	0.0 %	1.00
SHIRPA	coat color head	both	0.0 %	1.0
SHIRPA	coat color pattern abdomen	females	1.0 %	1.0
SHIRPA	coat color pattern abdomen	males	1.0 %	1.0
SHIRPA	coat color pattern abdomen	both	1.0 %	1.00
SHIRPA	coat color pattern back	females	0.0 %	1.0
SHIRPA	coat color pattern back	males	0.0 %	1.00
SHIRPA	coat color pattern back	both	0.0 %	1.00
SHIRPA	coat color pattern head	females	0.0 %	1.0
SHIRPA	coat color pattern head	males	0.0 %	1.0
SHIRPA	coat color pattern head	both	0.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	females	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	males	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	both	2.0 %	1.0
SHIRPA	coat hair back texture appearance	females	0.0 %	1.0
SHIRPA	coat hair back texture appearance	males	0.0 %	1.0
SHIRPA	coat hair back texture appearance	both	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	females	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	males	1.0 %	1.00
SHIRPA	coat hair distribution abdomen	both	1.0 %	1.0
SHIRPA	coat hair distribution back	females	0.0 %	1.0
SHIRPA	coat hair distribution back	males	0.0 %	1.0
SHIRPA	coat hair distribution back	both	0.0 %	1.00
SHIRPA	coat hair distribution head	females	1.0 %	1.00
SHIRPA	coat hair distribution head	males	1.0 %	1.0
SHIRPA	coat hair distribution head	both	1.0 %	1.0
SHIRPA	coat hair head texture appearance	females	0.0 %	1.0
SHIRPA	coat hair head texture appearance	males	0.0 %	1.0
SHIRPA	coat hair head texture appearance	both	0.0 %	1.0
SHIRPA	contact righting	females	5.0 %	1.0
SHIRPA	contact righting	males	5.0 %	1.00
SHIRPA	contact righting	both	5.0 %	1.00
SHIRPA	ear morphology	females	0.0 %	1.0
SHIRPA	ear morphology	males	0.0 %	1.0
SHIRPA	ear morphology	both	0.0 %	1.0
SHIRPA	fat distribution	females	0.0 %	1.0
SHIRPA	fat distribution	males	0.0 %	1.0
SHIRPA	fat distribution	both	0.0 %	1.0
SHIRPA	forelimb digit number	females	0.0 %	1.0
SHIRPA	forelimb digit number	males	0.0 %	1.0
SHIRPA	forelimb digit number	both	0.0 %	1.0
SHIRPA	forelimb digit position	females	0.0 %	1.0
SHIRPA	forelimb digit position	males	0.0 %	1.0
SHIRPA	forelimb digit position	both	0.0 %	1.0
SHIRPA	forelimb digit shape	females	0.0 %	1.0
SHIRPA	forelimb digit shape	males	0.0 %	1.0
SHIRPA	forelimb digit shape	both	0.0 %	1.0
SHIRPA	forelimb digit size	females	0.0 %	1.0
SHIRPA	forelimb digit size	males	0.0 %	1.0
SHIRPA	forelimb digit size	both	0.0 %	1.0
SHIRPA	forelimb footpads	females	0.0 %	1.0
SHIRPA	forelimb footpads	males	0.0 %	1.0
SHIRPA	forelimb footpads	both	0.0 %	1.0
SHIRPA	forelimb nail length	females	0.0 %	1.0
SHIRPA	forelimb nail length	males	0.0 %	1.0
SHIRPA	forelimb nail length	both	0.0 %	1.0
SHIRPA	forelimb nail number	females	0.0 %	1.0
SHIRPA	forelimb nail number	males	0.0 %	1.0
SHIRPA	forelimb nail number	both	0.0 %	1.0
SHIRPA	forelimb nail position	females	0.0 %	1.0
SHIRPA	forelimb nail position	males	0.0 %	1.0
SHIRPA	forelimb nail position	both	0.0 %	1.0
SHIRPA	forelimb nail shape	females	0.0 %	1.0
SHIRPA	forelimb nail shape	males	0.0 %	1.0
SHIRPA	forelimb nail shape	both	0.0 %	1.0
SHIRPA	forelimbs position	females	0.0 %	1.0
SHIRPA	forelimbs position	males	0.0 %	1.0
SHIRPA	forelimbs position	both	0.0 %	1.0
SHIRPA	forelimbs shape	females	0.0 %	1.0
SHIRPA	forelimbs shape	males	0.0 %	1.0
SHIRPA	forelimbs shape	both	0.0 %	1.0
SHIRPA	forelimbs size	females	0.0 %	1.0
SHIRPA	forelimbs size	males	0.0 %	1.0
SHIRPA	forelimbs size	both	0.0 %	1.0
SHIRPA	forepaw position	females	0.0 %	1.0
SHIRPA	forepaw position	males	0.0 %	1.0
SHIRPA	forepaw position	both	0.0 %	1.0
SHIRPA	forepaw shape	females	0.0 %	1.0
SHIRPA	forepaw shape	males	0.0 %	1.0
SHIRPA	forepaw shape	both	0.0 %	1.0
SHIRPA	forepaw size	females	0.0 %	1.0
SHIRPA	forepaw size	males	0.0 %	1.0
SHIRPA	forepaw size	both	0.0 %	1.0
SHIRPA	gait (fluidity)	females	0.0 %	1.0
SHIRPA	gait (fluidity)	males	0.0 %	1.00
SHIRPA	gait (fluidity)	both	0.0 %	1.0
SHIRPA	genitalia morphology	females	0.0 %	1.0
SHIRPA	genitalia morphology	males	0.0 %	1.0
SHIRPA	genitalia morphology	both	0.0 %	1.00
SHIRPA	genitalia presence	females	0.0 %	1.0
SHIRPA	genitalia presence	males	0.0 %	1.0
SHIRPA	genitalia presence	both	0.0 %	1.0
SHIRPA	genitalia size	females	0.0 %	1.0
SHIRPA	genitalia size	males	0.0 %	1.0
SHIRPA	genitalia size	both	0.0 %	1.00
SHIRPA	head bobbing	females	0.0 %	1.0
SHIRPA	head bobbing	males	0.0 %	1.0
SHIRPA	head bobbing	both	0.0 %	1.0
SHIRPA	head morphology	females	0.0 %	1.0
SHIRPA	head morphology	males	0.0 %	1.00
SHIRPA	head morphology	both	0.0 %	1.0
SHIRPA	head size	females	0.0 %	1.0
SHIRPA	head size	males	0.0 %	1.0
SHIRPA	head size	both	0.0 %	1.0
SHIRPA	hindlimb digit number	females	1.0 %	1.0
SHIRPA	hindlimb digit number	males	0.0 %	1.0
SHIRPA	hindlimb digit number	both	0.0 %	1.0
SHIRPA	hindlimb digit position	females	0.0 %	1.0
SHIRPA	hindlimb digit position	males	0.0 %	1.0
SHIRPA	hindlimb digit position	both	0.0 %	1.0
SHIRPA	hindlimb digit shape	females	0.0 %	1.0
SHIRPA	hindlimb digit shape	males	0.0 %	1.0
SHIRPA	hindlimb digit shape	both	0.0 %	1.00
SHIRPA	hindlimb digit size	females	0.0 %	1.0
SHIRPA	hindlimb digit size	males	0.0 %	1.0
SHIRPA	hindlimb digit size	both	0.0 %	1.00
SHIRPA	hindlimb nail length	females	0.0 %	1.0
SHIRPA	hindlimb nail length	males	0.0 %	1.0
SHIRPA	hindlimb nail length	both	0.0 %	1.0
SHIRPA	hindlimb nail number	females	0.0 %	1.0
SHIRPA	hindlimb nail number	males	1.0 %	1.0
SHIRPA	hindlimb nail number	both	0.0 %	1.0
SHIRPA	hindlimb nail position	females	0.0 %	1.0
SHIRPA	hindlimb nail position	males	0.0 %	1.0
SHIRPA	hindlimb nail position	both	0.0 %	1.0
SHIRPA	hindlimb nail shape	females	0.0 %	1.0
SHIRPA	hindlimb nail shape	males	0.0 %	1.0
SHIRPA	hindlimb nail shape	both	0.0 %	1.0
SHIRPA	hindlimbs footpads	females	0.0 %	1.0
SHIRPA	hindlimbs footpads	males	0.0 %	1.0
SHIRPA	hindlimbs footpads	both	0.0 %	1.0
SHIRPA	hindlimbs position	females	0.0 %	1.0
SHIRPA	hindlimbs position	males	0.0 %	1.0
SHIRPA	hindlimbs position	both	0.0 %	1.0
SHIRPA	hindlimbs shape	females	0.0 %	1.0
SHIRPA	hindlimbs shape	males	0.0 %	1.0
SHIRPA	hindlimbs shape	both	0.0 %	1.0
SHIRPA	hindlimbs size	females	0.0 %	1.0
SHIRPA	hindlimbs size	males	0.0 %	1.0
SHIRPA	hindlimbs size	both	0.0 %	1.0
SHIRPA	hindpaw position	females	0.0 %	1.0
SHIRPA	hindpaw position	males	0.0 %	1.0
SHIRPA	hindpaw position	both	0.0 %	1.0
SHIRPA	hindpaw shape	females	0.0 %	1.0
SHIRPA	hindpaw shape	males	0.0 %	1.0
SHIRPA	hindpaw shape	both	0.0 %	1.0
SHIRPA	hindpaw size	females	0.0 %	1.0
SHIRPA	hindpaw size	males	0.0 %	1.0
SHIRPA	hindpaw size	both	0.0 %	1.0
SHIRPA	limb grasp	females	9.0 %	1.0
SHIRPA	limb grasp	males	7.0 %	0.375
SHIRPA	limb grasp	both	1.0 %	1.0
SHIRPA	lower lip morphology	females	0.0 %	1.0
SHIRPA	lower lip morphology	males	0.0 %	1.0
SHIRPA	lower lip morphology	both	0.0 %	1.0
SHIRPA	lower teeth appearance	females	0.0 %	1.0
SHIRPA	lower teeth appearance	males	0.0 %	1.00
SHIRPA	lower teeth appearance	both	0.0 %	1.0
SHIRPA	mouth morphology	females	0.0 %	1.0
SHIRPA	mouth morphology	males	0.0 %	1.00
SHIRPA	mouth morphology	both	0.0 %	1.0
SHIRPA	salivation	females	0.0 %	1.0
SHIRPA	salivation	males	0.0 %	1.0
SHIRPA	salivation	both	0.0 %	1.0
SHIRPA	skin color back paws	females	0.0 %	1.0
SHIRPA	skin color back paws	males	0.0 %	1.0
SHIRPA	skin color back paws	both	0.0 %	1.0
SHIRPA	skin color ear	females	0.0 %	1.0
SHIRPA	skin color ear	males	0.0 %	1.0
SHIRPA	skin color ear	both	0.0 %	1.0
SHIRPA	skin color front paws	females	0.0 %	1.0
SHIRPA	skin color front paws	males	0.0 %	1.0
SHIRPA	skin color front paws	both	0.0 %	1.0
SHIRPA	skin color snout	females	0.0 %	1.0
SHIRPA	skin color snout	males	0.0 %	1.0
SHIRPA	skin color snout	both	0.0 %	1.0
SHIRPA	skin color tail	females	0.0 %	1.0
SHIRPA	skin color tail	males	0.0 %	1.0
SHIRPA	skin color tail	both	0.0 %	1.0
SHIRPA	skin color whole body	females	0.0 %	1.0
SHIRPA	skin color whole body	males	0.0 %	1.0
SHIRPA	skin color whole body	both	0.0 %	1.0
SHIRPA	skin texture back paw	females	0.0 %	1.0
SHIRPA	skin texture back paw	males	0.0 %	1.0
SHIRPA	skin texture back paw	both	0.0 %	1.0
SHIRPA	skin texture ear	females	0.0 %	1.0
SHIRPA	skin texture ear	males	0.0 %	1.0
SHIRPA	skin texture ear	both	0.0 %	1.0
SHIRPA	skin texture front paws	females	0.0 %	1.0
SHIRPA	skin texture front paws	males	0.0 %	1.0
SHIRPA	skin texture front paws	both	0.0 %	1.0
SHIRPA	skin texture snout	females	0.0 %	1.0
SHIRPA	skin texture snout	males	0.0 %	1.0
SHIRPA	skin texture snout	both	0.0 %	1.0
SHIRPA	skin texture tail	females	0.0 %	1.0
SHIRPA	skin texture tail	males	0.0 %	1.0
SHIRPA	skin texture tail	both	0.0 %	1.0
SHIRPA	skin texture whole body	females	0.0 %	1.0
SHIRPA	skin texture whole body	males	0.0 %	1.00
SHIRPA	skin texture whole body	both	0.0 %	1.00
SHIRPA	snout size	females	0.0 %	1.0
SHIRPA	snout size	males	1.0 %	1.0
SHIRPA	snout size	both	0.0 %	1.0
SHIRPA	startle response	females	0.0 %	1.0
SHIRPA	startle response	males	0.0 %	1.00
SHIRPA	startle response	both	0.0 %	1.0
SHIRPA	tail curvature	females	0.0 %	1.00
SHIRPA	tail curvature	males	0.0 %	1.0
SHIRPA	tail curvature	both	0.0 %	1.00
SHIRPA	tail elevation	females	1.0 %	1.0
SHIRPA	tail elevation	males	2.0 %	1.0
SHIRPA	tail elevation	both	1.0 %	1.0
SHIRPA	tail length	females	0.0 %	1.0
SHIRPA	tail length	males	0.0 %	1.0
SHIRPA	tail length	both	0.0 %	1.0
SHIRPA	tail morphology	females	0.0 %	1.0
SHIRPA	tail morphology	males	0.0 %	1.0
SHIRPA	tail morphology	both	0.0 %	1.00
SHIRPA	tail presence	females	0.0 %	1.0
SHIRPA	tail presence	males	0.0 %	1.0
SHIRPA	tail presence	both	0.0 %	1.0
SHIRPA	tail shape	females	0.0 %	1.0
SHIRPA	tail shape	males	0.0 %	1.0
SHIRPA	tail shape	both	0.0 %	1.0
SHIRPA	tail thickness	females	0.0 %	1.0
SHIRPA	tail thickness	males	0.0 %	1.0
SHIRPA	tail thickness	both	0.0 %	1.0
SHIRPA	teeth presence	females	0.0 %	1.0
SHIRPA	teeth presence	males	0.0 %	1.00
SHIRPA	teeth presence	both	0.0 %	1.0
SHIRPA	transfer arousal	females	1.0 %	1.0
SHIRPA	transfer arousal	males	2.0 %	1.00
SHIRPA	transfer arousal	both	1.0 %	1.0
SHIRPA	tremor	females	0.0 %	1.0
SHIRPA	tremor	males	0.0 %	1.0
SHIRPA	tremor	both	0.0 %	1.00
SHIRPA	trunk curl	females	0.0 %	1.0
SHIRPA	trunk curl	males	0.0 %	1.0
SHIRPA	trunk curl	both	0.0 %	1.00
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	females	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	males	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	both	0.0 %	1.0
SHIRPA	upper lip morphology	females	0.0 %	1.0
SHIRPA	upper lip morphology	males	0.0 %	1.0
SHIRPA	upper lip morphology	both	0.0 %	1.0
SHIRPA	upper teeth appearance	females	0.0 %	1.0
SHIRPA	upper teeth appearance	males	0.0 %	1.0
SHIRPA	upper teeth appearance	both	0.0 %	1.0
SHIRPA	vibrissae appearance	females	2.0 %	1.0
SHIRPA	vibrissae appearance	males	1.0 %	1.0
SHIRPA	vibrissae appearance	both	1.0 %	1.0
SHIRPA	vibrissae presence	females	2.0 %	1.00
SHIRPA	vibrissae presence	males	1.0 %	1.0
SHIRPA	vibrissae presence	both	2.0 %	1.0
SHIRPA	vocalization	females	2.0 %	1.0
SHIRPA	vocalization	males	2.0 %	1.0
SHIRPA	vocalization	both	2.0 %	1.0

GENOTYPE CORRELATION PLOT

Correlate Fam43a^em1(IMPC)J/Mmjax -/- with genotype:

This genotype correlation visualization can include both EAP and LAP measures.