MPD: JaxKOMP-EAP genotype: U2surp<sup>em1(IMPC)J</sup>/Mmjax -/+

JaxKOMP-EAP effect sizes: U2surp^em1(IMPC)J/Mmjax -/+ Gene U2surp

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	3.1250	2.4888	0.66907	0.661	0.224
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	2.9225	4.0874	0.65900	0.831	0.483
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	12.069	3.8173	1.5986	0.103	0.00540
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	3.1250	2.4587	0.40870	0.609	0.219
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	-0.36868	2.4671	-0.081401	0.964	0.883
body composition	body length	-0.11227	0.11026	-0.97882	0.615	0.318
body composition	body weight (at time of DXA)	-0.43874	0.95341	-0.24743	0.812	0.649
body composition	bone area, whole body scan, head excluded	-0.47106	0.17559	-1.5070	0.0929	0.0130
body composition	bone mineral content of whole body scan, head excluded	-0.054323	0.013773	-2.1779	0.0157	0.000606
body composition	bone mineral content to body weight ratio	-0.0017276	0.00054374	-1.7226	0.0432	0.00393
body composition	bone mineral density of whole body scan, head excluded	-0.0034216	0.00064483	-2.4816	0.00167	0.0000192
body composition	fat tissue mass of whole body scan, head excluded	0.62456	0.46286	0.91429	0.430	0.190
body composition	fat tissue mass to body weight ratio	0.023589	0.020477	1.0257	0.501	0.261
body composition	lean tissue mass of whole body scan, head excluded	-1.3548	0.42841	-2.2241	0.0671	0.00421
body composition	lean tissue mass to body weight ratio	-0.030229	0.019355	-1.5327	0.363	0.131
body composition	percent fat, whole body scan, head excluded	2.5570	1.4716	1.1759	0.279	0.0951
body composition	ratio of soft-tissue attenuation coefficients	-0.0028401	0.0016355	-1.1746	0.278	0.0953
body composition	tissue area	-0.28057	0.22630	-0.75842	0.522	0.227
body composition	total tissue mass, whole body scan, head excluded	-0.68784	0.33043	-1.8895	0.190	0.0482
clinical blood chemistry	alanine transaminase (plasma ALT)	-2.2485	6.1855	-0.24399	0.918	0.718
clinical blood chemistry	albumin (plasma Alb)	0.16246	0.33552	0.28321	0.856	0.630
clinical blood chemistry	alkaline phosphatase (plasma ALP)	8.4523	3.4942	0.89070	0.107	0.0190
clinical blood chemistry	aspartate transaminase (plasma AST)	-5.6507	6.8869	-0.28451	0.718	0.416
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	-0.14585	0.12315	-0.46156	0.638	0.241
clinical blood chemistry	blood urea nitrogen (BUN)	0.49517	1.2852	0.18084	0.854	0.702
clinical blood chemistry	calcium (plasma Ca)	-0.087138	0.073118	-0.27425	0.459	0.238
clinical blood chemistry	creatinine (plasma)	0.017692	0.023053	0.54585	0.678	0.446
clinical blood chemistry	glucose (plasma GLU, no fast)	-24.366	11.900	-0.60568	0.148	0.0455
clinical blood chemistry	HDL cholesterol (plasma HDL)	-0.021569	2.8317	-0.33265	0.998	0.994
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	0.0095191	0.0097185	0.37820	0.655	0.332
clinical blood chemistry	phosphorus (plasma phosphate)	-0.40973	0.33583	-0.70477	0.511	0.228
clinical blood chemistry	total bilirubin (plasma TBIL)	0.0068955	0.0090621	0.47106	0.764	0.450
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	-1.5728	3.9262	-0.51610	0.887	0.690
clinical blood chemistry	total protein (plasma TP)	0.89077	0.52077	0.61302	0.349	0.0929
clinical blood chemistry	triglyceride (plasma TG, no fast)	31.343	29.583	1.6210	0.585	0.294
glucose tolerance test	amount glucose injected	1.2920	2.4303	0.73036	0.864	0.597
glucose tolerance test	plasma glucose, 0min	0.35585	3.8936	-0.19758	0.969	0.928
glucose tolerance test	plasma glucose, 15min	37.836	17.081	1.1457	0.213	0.0308
glucose tolerance test	plasma glucose, 30min	9.4689	12.813	0.39732	0.744	0.463
glucose tolerance test	plasma glucose, 60min	-2.5975	11.260	0.039820	0.929	0.818
glucose tolerance test	plasma glucose, 120min	-1.5961	4.2858	-0.23694	0.892	0.711
grip strength	body weight (at time of grip strength test)	-1.0151	0.48484	-0.71887	0.126	0.0406
grip strength	forelimb and hindlimb grip strength (mean of trials), average	2.5085	3.7594	0.42648	0.697	0.507
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	0.064175	0.17808	0.27500	0.841	0.720
grip strength	forelimb and hindlimb grip strength by trial, trial1	1.9588	5.9355	0.36367	0.893	0.743
grip strength	forelimb and hindlimb grip strength by trial, trial2	5.9338	5.4275	0.62870	0.534	0.279
grip strength	forelimb and hindlimb grip strength by trial, trial3	-0.96008	5.6400	0.13841	0.943	0.865
grip strength	forelimb grip strength (mean of trials), average	4.9967	3.3812	0.95513	0.374	0.145
grip strength	forelimb grip strength (mean of trials), average normalized to bw	0.21523	0.17436	0.80133	0.493	0.222
grip strength	forelimb grip strength by trial, trial1	5.0508	4.8011	0.85871	0.645	0.297
grip strength	forelimb grip strength by trial, trial2	3.3501	4.2631	0.61285	0.747	0.435
grip strength	forelimb grip strength by trial, trial3	4.7749	4.8310	0.76385	0.653	0.327
heart weight	heart weight, normalized to body weight	-0.25238	0.12020	-1.4212	0.159	0.0426
heart weight	heart weight, weight	-5.5250	3.5799	-1.1345	0.315	0.131
hematology	basophil differential (percent of total WBC)	0.16986	0.082243	1.8113	0.386	0.0459
hematology	eosinophil differential (percent of total WBC)	0.070508	0.19066	0.27913	0.906	0.714
hematology	hematocrit (HCT)	2.0195	0.38850	1.6433	0.00116	0.00000763
hematology	lymphocyte differential (percent of total WBC)	1.2581	1.0697	0.45384	0.501	0.247
hematology	mean corpuscular hemoglobin (CHr)	-0.020102	0.066428	-0.14638	0.889	0.764
hematology	mean platelet volume (MPV)	0.16096	0.034097	0.80200	0.000770	0.0000333
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	-0.12321	0.11454	-0.29030	0.654	0.289
hematology	mean RBC corpuscular volume (MCV)	0.093096	0.22415	0.21206	0.837	0.680
hematology	measured hemoglobin (mHGB)	0.56749	0.12494	1.2197	0.00479	0.0000575
hematology	monocyte differential (percent of total WBC)	-0.71630	0.28194	-1.3860	0.196	0.0155
hematology	neutrophil differential (percent of total WBC)	-0.79332	0.77934	-0.36611	0.557	0.315
hematology	platelet count (PLT; units per volume x 10³)	-75.741	49.714	-0.93237	0.504	0.136
hematology	RBC corpuscular distribution width (RDW)	0.15830	0.14449	0.52079	0.549	0.280
hematology	red blood cell count (RBC; per volume x 10⁶)	0.42884	0.10083	1.4809	0.00566	0.000138
hematology	reticulocyte count (Retic; units per volume x 10⁹)	9.7627	15.565	0.52519	0.832	0.534
hematology	reticulocyte differential (percent of total RBC)	-0.039518	0.14066	0.056148	0.912	0.780
hematology	white blood cell count (WBC; units per volume x 10³)	0.97252	0.60441	0.82961	0.278	0.116
holeboard	number of hole pokes by individual hole number, 20 min test, 1	-0.40354	0.70098	-0.32731	0.859	0.567
holeboard	number of hole pokes by individual hole number, 20 min test, 2	-0.82250	0.47724	-1.1723	0.610	0.0900
holeboard	number of hole pokes by individual hole number, 20 min test, 3	-0.36624	0.58831	-0.54289	0.895	0.536
holeboard	number of hole pokes by individual hole number, 20 min test, 4	-0.86283	0.75865	-0.80841	0.715	0.260
holeboard	number of hole pokes by individual hole number, 20 min test, 5	-0.80913	0.42213	-1.2100	0.565	0.0601
holeboard	number of hole pokes by individual hole number, 20 min test, 6	-0.64250	0.32847	-1.8120	0.576	0.0552
holeboard	number of hole pokes by individual hole number, 20 min test, 7	-0.55666	0.27261	-1.5547	0.621	0.0457
holeboard	number of hole pokes by individual hole number, 20 min test, 8	-0.51250	0.48913	-0.75570	0.790	0.299
holeboard	number of hole pokes by individual hole number, 20 min test, 9	-0.86967	0.38119	-1.3904	0.354	0.0262
holeboard	number of hole pokes by individual hole number, 20 min test, 10	-0.42760	0.34568	-1.2521	0.769	0.221
holeboard	number of hole pokes by individual hole number, 20 min test, 11	0.0073085	0.29668	0.028719	0.995	0.980
holeboard	number of hole pokes by individual hole number, 20 min test, 12	-0.13500	0.41388	-0.12515	0.952	0.745
holeboard	number of hole pokes by individual hole number, 20 min test, 13	-0.65471	0.77158	-0.56906	0.755	0.400
holeboard	number of hole pokes by individual hole number, 20 min test, 14	-0.99656	0.40936	-1.5226	0.321	0.0180
holeboard	number of hole pokes by individual hole number, 20 min test, 15	-0.75498	0.52026	-1.1206	0.634	0.152
holeboard	number of hole pokes by individual hole number, 20 min test, 16	0.15628	0.60253	0.16949	0.942	0.796
holeboard	total number of hole pokes, 20 min test	-8.6666	3.9725	-1.1561	0.205	0.0331
light / dark	latency to enter dark zone, 20 min test	143.63	38.425	2.0775	0.0637	0.000426
light / dark	number of transitions between light and dark zones, 20 min test	-4.4094	4.5704	-0.33898	0.647	0.339
light / dark	percentage of total time in dark zone, 20 min test	6.7320	4.2178	1.3812	0.464	0.116
light / dark	percentage of total time in light zone, 20 min test	-6.7314	4.2178	-1.3848	0.463	0.116
light / dark	time mobile in dark zone, 20 min test	-3.7908	4.2069	-0.36487	0.667	0.371
light / dark	time mobile in light zone, 20 min test	-1.4784	4.2202	-0.33611	0.872	0.727
light / dark	time spent in dark zone, 20 min test	-26.679	49.738	-0.20007	0.871	0.594
light / dark	time spent in light zone, 20 min test	26.680	49.738	0.20007	0.871	0.594
open field	average speed in center of arena, 20 min test	-1.0946	0.32882	-2.0688	0.0430	0.00152
open field	average speed in periphery of arena, 20 min test	-0.49975	0.16396	-2.1168	0.0289	0.00347
open field	distance traveled habituation ratio, 20 min test	-5.9954	5.6347	-0.48189	0.616	0.292
open field	distance traveled in center of arena, 20 min test	-215.82	101.97	-1.6843	0.167	0.0387
open field	distance traveled in periphery of arena, 20 min test	-610.26	173.24	-2.5519	0.0124	0.000841
open field	distance traveled slope, 20 min test	-6.8148	5.1297	-0.58883	0.510	0.189
open field	distance traveled, 20 min test, 1st 5min	-174.58	61.154	-1.6415	0.0464	0.00597
open field	distance traveled, 20 min test, 2nd 5min	-182.55	57.991	-2.3198	0.0286	0.00260
open field	distance traveled, 20 min test, 3rd 5min	-217.40	62.090	-2.4324	0.0137	0.000898
open field	distance traveled, 20 min test, 4th 5min	-211.70	63.443	-2.5519	0.0175	0.00148
open field	number of clockwise revolution episodes, 20 min test	-2.2337	1.1004	-1.7242	0.272	0.0470
open field	number of counter-clockwise revolution episodes, 20 min test	-4.0098	1.7785	-2.6738	0.184	0.0279
open field	number of rears in 5 min bins, 20 min test, 1st 5min	-2.6072	2.3699	-0.91921	0.542	0.276
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	-3.2493	3.1498	-1.1618	0.594	0.307
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	-4.3830	3.3661	-1.3117	0.473	0.198
open field	number of rears in 5 min bins, 20 min test, 4th 5min	-4.0705	3.2247	-1.2219	0.481	0.212
open field	percentage of total time in center of arena, 20 min test	7.4560	3.5530	1.3992	0.254	0.0402
open field	percentage of total time in center of arena, slope, 20 min test	-1.5866	1.7346	-0.74842	0.801	0.364
open field	percentage of total time in center, habituation ratio, 20 min test	-1.8745	1.7257	-0.85974	0.758	0.282
open field	percentage of total time in corners of arena, 20 min test	-5.1039	2.2304	-0.65565	0.195	0.0258
open field	percentage of total time in corners, habituation ratio, 20 min test	1.7552	1.4866	0.51994	0.748	0.243
open field	percentage of total time in corners, slope, 20 min test	1.4510	1.4523	0.39031	0.788	0.322
open field	permanence time in center of arena, 20 min test	89.455	42.634	1.4028	0.254	0.0403
open field	permanence time in corners of arena, 20 min test	-61.241	26.764	-0.65565	0.195	0.0258
open field	permanence time in periphery of arena, 20 min test	-89.454	42.634	-1.4064	0.254	0.0403
open field	total distance traveled, 20 min test	-785.69	223.29	-2.3004	0.0102	0.000851
open field	total number of rears, 20 min test	-13.357	10.308	-1.2685	0.440	0.200
open field	whole arena average speed, 20 min test	-0.65573	0.18598	-2.3004	0.0100	0.000832
open field	whole arena resting time, 20 min test	79.096	23.176	2.5186	0.0115	0.00118
open field	whole arena time spent mobile, 20 min test	-15.703	4.4205	-1.1913	0.00856	0.000766
open field	whole arena time spent vertical, 20 min test	-11.911	6.8772	-1.0251	0.340	0.0887
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	-1.2317	1.1612	-0.33243	0.600	0.293
startle / PPI	average baseline movement during background noise	-2.9476	2.0279	-1.9206	0.709	0.158
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	0.027703	0.080499	0.13704	0.890	0.734
startle / PPI	average of each corrected percent pre-pulse inhibition value	0.023741	0.077894	0.15989	0.904	0.763
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-8.2933	9.4592	-0.84923	0.879	0.389
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	3.8612	6.5392	0.32140	0.816	0.560
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	7.8776	8.7432	0.70515	0.677	0.376
startle / PPI	average startle response to full pulse (120 dB)	-12.567	55.284	-0.072221	0.933	0.822
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	18.422	59.902	0.59437	0.882	0.761
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-21.692	52.158	-0.26581	0.814	0.681
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-35.905	47.042	-0.65223	0.649	0.452
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	-1.9284	1.2566	-1.2844	0.677	0.137
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	-0.16397	2.5474	-0.10035	0.991	0.949
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	0.90568	2.3217	0.27307	0.921	0.700
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.094876	0.10042	-0.85124	0.869	0.353
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.049153	0.071685	0.32473	0.765	0.499
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.084605	0.096115	0.47735	0.649	0.387
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	-10.911	55.480	-0.034335	0.940	0.846
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	19.324	59.869	0.61117	0.880	0.750
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	-27.113	51.627	-0.36450	0.763	0.604
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	-37.237	46.686	-0.66266	0.638	0.433
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.10069	0.10000	-0.86746	0.860	0.323
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.060851	0.076265	0.39409	0.728	0.432
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.078345	0.099080	0.40168	0.679	0.437
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	4.2740	204.45	0.21963	0.992	0.983
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	110.56	218.15	0.75267	0.794	0.617
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	-60.109	196.47	-0.14411	0.858	0.762
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	-113.87	176.03	-0.50632	0.707	0.524
startle / PPI	maximum baseline movement during background noise	-9.2048	4.9444	-2.3454	0.539	0.0740
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-9.0763	9.6523	-0.86135	0.890	0.356
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	5.8170	7.1202	0.43894	0.740	0.421
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	7.3496	9.2531	0.55307	0.709	0.435
startle / PPI	maximum startle response to full pulse (120 dB)	-2.8693	204.05	0.18673	0.994	0.989
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	103.81	217.77	0.70515	0.810	0.638
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-52.850	197.34	-0.11021	0.877	0.791
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-110.23	176.87	-0.50791	0.712	0.539
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	-6.6167	2.4250	-1.7226	0.366	0.0113
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	-3.5568	5.9687	-0.99501	0.889	0.557
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	1.4142	5.7450	0.096125	0.933	0.807

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Sex	Trait Effect	P-value
eye morphology	anterior chamber depth	females	1.0 %	1.0
eye morphology	anterior chamber depth	males	0.0 %	1.0
eye morphology	anterior chamber depth	both	1.0 %	1.0
eye morphology	bulging eye	females	1.0 %	1.0
eye morphology	bulging eye	males	0.0 %	1.0
eye morphology	bulging eye	both	1.0 %	1.00
eye morphology	cornea	females	4.0 %	1.0
eye morphology	cornea	males	2.0 %	1.0
eye morphology	cornea	both	3.0 %	1.00
eye morphology	cornea opacity	females	5.0 %	1.00
eye morphology	cornea opacity	males	1.0 %	1.0
eye morphology	cornea opacity	both	3.0 %	1.0
eye morphology	cornea vascularization	females	3.0 %	1.0
eye morphology	cornea vascularization	males	1.0 %	1.0
eye morphology	cornea vascularization	both	2.0 %	1.0
eye morphology	corneal deposits	females	2.0 %	1.0
eye morphology	corneal deposits	males	1.0 %	1.0
eye morphology	corneal deposits	both	1.0 %	1.00
eye morphology	corneal mineralization	females	2.0 %	1.0
eye morphology	corneal mineralization	males	1.0 %	1.0
eye morphology	corneal mineralization	both	1.0 %	1.0
eye morphology	corneal scleralization	females	3.0 %	1.00
eye morphology	corneal scleralization	males	1.0 %	1.0
eye morphology	corneal scleralization	both	2.0 %	1.0
eye morphology	corneal ulcer	females	1.0 %	1.0
eye morphology	corneal ulcer	males	1.0 %	1.0
eye morphology	corneal ulcer	both	1.0 %	1.0
eye morphology	eye closure	females	1.0 %	1.00
eye morphology	eye closure	males	0.0 %	1.0
eye morphology	eye closure	both	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	females	2.0 %	1.00
eye morphology	eye hemorrhage or blood presence	males	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	both	1.0 %	1.0
eye morphology	eyelid morphology	females	1.0 %	1.0
eye morphology	eyelid morphology	males	0.0 %	1.0
eye morphology	eyelid morphology	both	1.0 %	1.0
eye morphology	eyes (present, absent)	females	1.0 %	1.0
eye morphology	eyes (present, absent)	males	0.0 %	1.0
eye morphology	eyes (present, absent)	both	0.0 %	1.0
eye morphology	fusion between cornea and lens	females	4.0 %	1.00
eye morphology	fusion between cornea and lens	males	2.0 %	1.0
eye morphology	fusion between cornea and lens	both	3.0 %	1.0
eye morphology	iris pigmentation	females	2.0 %	1.0
eye morphology	iris pigmentation	males	1.0 %	1.0
eye morphology	iris pigmentation	both	2.0 %	1.0
eye morphology	iris transillumination	females	2.0 %	1.00
eye morphology	iris transillumination	males	1.0 %	1.00
eye morphology	iris transillumination	both	1.0 %	1.00
eye morphology	irispupil	females	4.0 %	1.00
eye morphology	irispupil	males	3.0 %	1.0
eye morphology	irispupil	both	3.0 %	1.0
eye morphology	lacrimation	females	3.0 %	1.0
eye morphology	lacrimation	males	2.0 %	1.0
eye morphology	lacrimation	both	3.0 %	1.0
eye morphology	lens	females	10.0 %	1.00
eye morphology	lens	males	8.0 %	1.00
eye morphology	lens	both	9.0 %	1.0
eye morphology	lens opacity	females	9.0 %	1.0
eye morphology	lens opacity	males	12.0 %	0.331
eye morphology	lens opacity	both	4.0 %	0.679
eye morphology	narrow eye opening	females	2.0 %	1.0
eye morphology	narrow eye opening	males	1.0 %	1.0
eye morphology	narrow eye opening	both	1.0 %	1.00
eye morphology	optic disc	females	4.0 %	1.00
eye morphology	optic disc	males	2.0 %	1.00
eye morphology	optic disc	both	3.0 %	1.00
eye morphology	persistence of hyaloid vascular system	females	14.0 %	1.0
eye morphology	persistence of hyaloid vascular system	males	5.0 %	1.0
eye morphology	persistence of hyaloid vascular system	both	9.0 %	1.00
eye morphology	pupil dilation	females	12.0 %	0.0361
eye morphology	pupil dilation	males	1.0 %	1.00
eye morphology	pupil dilation	both	6.0 %	0.0890
eye morphology	pupil light response	females	2.0 %	1.00
eye morphology	pupil light response	males	1.0 %	1.0
eye morphology	pupil light response	both	2.0 %	1.0
eye morphology	pupil position	females	4.0 %	1.00
eye morphology	pupil position	males	3.0 %	1.0
eye morphology	pupil position	both	4.0 %	1.0
eye morphology	pupil shape	females	3.0 %	1.00
eye morphology	pupil shape	males	2.0 %	1.0
eye morphology	pupil shape	both	3.0 %	1.0
eye morphology	retina	females	10.0 %	1.0
eye morphology	retina	males	12.0 %	0.424
eye morphology	retina	both	6.0 %	0.634
eye morphology	retinal blood vessels	females	4.0 %	1.0
eye morphology	retinal blood vessels	males	2.0 %	1.0
eye morphology	retinal blood vessels	both	3.0 %	1.0
eye morphology	retinal blood vessels pattern	females	5.0 %	1.0
eye morphology	retinal blood vessels pattern	males	2.0 %	1.00
eye morphology	retinal blood vessels pattern	both	4.0 %	1.00
eye morphology	retinal blood vessels structure	females	4.0 %	1.00
eye morphology	retinal blood vessels structure	males	2.0 %	1.0
eye morphology	retinal blood vessels structure	both	3.0 %	1.0
eye morphology	retinal pigmentation	females	12.0 %	1.0
eye morphology	retinal pigmentation	males	14.0 %	1.0
eye morphology	retinal pigmentation	both	13.0 %	1.0
eye morphology	retinal structure	females	4.0 %	1.00
eye morphology	retinal structure	males	2.0 %	1.00
eye morphology	retinal structure	both	3.0 %	1.00
eye morphology	synechia	females	4.0 %	1.0
eye morphology	synechia	males	2.0 %	1.00
eye morphology	synechia	both	3.0 %	1.00
eye morphology	vitreous	females	4.0 %	1.00
eye morphology	vitreous	males	2.0 %	1.0
eye morphology	vitreous	both	3.0 %	1.0
SHIRPA	activity body position	females	1.0 %	1.0
SHIRPA	activity body position	males	2.0 %	1.0
SHIRPA	activity body position	both	1.0 %	1.00
SHIRPA	aggression	females	0.0 %	1.00
SHIRPA	aggression	males	1.0 %	1.0
SHIRPA	aggression	both	1.0 %	1.0
SHIRPA	body length	females	0.0 %	1.0
SHIRPA	body length	males	0.0 %	1.00
SHIRPA	body length	both	0.0 %	1.00
SHIRPA	body position	females	0.0 %	1.0
SHIRPA	body position	males	1.0 %	1.0
SHIRPA	body position	both	0.0 %	1.0
SHIRPA	body thickness	females	1.0 %	1.0
SHIRPA	body thickness	males	0.0 %	1.0
SHIRPA	body thickness	both	0.0 %	1.0
SHIRPA	coat color abdomen	females	3.0 %	1.00
SHIRPA	coat color abdomen	males	4.0 %	1.0
SHIRPA	coat color abdomen	both	4.0 %	1.0
SHIRPA	coat color back	females	0.0 %	1.0
SHIRPA	coat color back	males	0.0 %	1.00
SHIRPA	coat color back	both	0.0 %	1.00
SHIRPA	coat color head	females	0.0 %	1.0
SHIRPA	coat color head	males	0.0 %	1.00
SHIRPA	coat color head	both	0.0 %	1.0
SHIRPA	coat color pattern abdomen	females	1.0 %	1.0
SHIRPA	coat color pattern abdomen	males	1.0 %	1.0
SHIRPA	coat color pattern abdomen	both	1.0 %	1.0
SHIRPA	coat color pattern back	females	0.0 %	1.0
SHIRPA	coat color pattern back	males	0.0 %	1.00
SHIRPA	coat color pattern back	both	0.0 %	1.0
SHIRPA	coat color pattern head	females	0.0 %	1.0
SHIRPA	coat color pattern head	males	0.0 %	1.0
SHIRPA	coat color pattern head	both	0.0 %	1.00
SHIRPA	coat hair abdomen texture appearance	females	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	males	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	both	2.0 %	1.0
SHIRPA	coat hair back texture appearance	females	0.0 %	1.0
SHIRPA	coat hair back texture appearance	males	0.0 %	1.0
SHIRPA	coat hair back texture appearance	both	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	females	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	males	1.0 %	1.00
SHIRPA	coat hair distribution abdomen	both	1.0 %	1.00
SHIRPA	coat hair distribution back	females	0.0 %	1.0
SHIRPA	coat hair distribution back	males	0.0 %	1.0
SHIRPA	coat hair distribution back	both	0.0 %	1.0
SHIRPA	coat hair distribution head	females	1.0 %	1.00
SHIRPA	coat hair distribution head	males	1.0 %	1.0
SHIRPA	coat hair distribution head	both	1.0 %	1.0
SHIRPA	coat hair head texture appearance	females	0.0 %	1.00
SHIRPA	coat hair head texture appearance	males	0.0 %	1.0
SHIRPA	coat hair head texture appearance	both	0.0 %	1.0
SHIRPA	contact righting	females	5.0 %	1.0
SHIRPA	contact righting	males	5.0 %	1.00
SHIRPA	contact righting	both	5.0 %	1.00
SHIRPA	ear morphology	females	0.0 %	1.0
SHIRPA	ear morphology	males	0.0 %	1.0
SHIRPA	ear morphology	both	0.0 %	1.0
SHIRPA	fat distribution	females	0.0 %	1.0
SHIRPA	fat distribution	males	0.0 %	1.0
SHIRPA	fat distribution	both	0.0 %	1.00
SHIRPA	forelimb digit number	females	0.0 %	1.00
SHIRPA	forelimb digit number	males	0.0 %	1.0
SHIRPA	forelimb digit number	both	0.0 %	1.00
SHIRPA	forelimb digit position	females	0.0 %	1.0
SHIRPA	forelimb digit position	males	0.0 %	1.0
SHIRPA	forelimb digit position	both	0.0 %	1.0
SHIRPA	forelimb digit shape	females	0.0 %	1.0
SHIRPA	forelimb digit shape	males	0.0 %	1.0
SHIRPA	forelimb digit shape	both	0.0 %	1.0
SHIRPA	forelimb digit size	females	0.0 %	1.0
SHIRPA	forelimb digit size	males	0.0 %	1.0
SHIRPA	forelimb digit size	both	0.0 %	1.0
SHIRPA	forelimb footpads	females	0.0 %	1.0
SHIRPA	forelimb footpads	males	0.0 %	1.0
SHIRPA	forelimb footpads	both	0.0 %	1.0
SHIRPA	forelimb nail length	females	0.0 %	1.0
SHIRPA	forelimb nail length	males	0.0 %	1.0
SHIRPA	forelimb nail length	both	0.0 %	1.0
SHIRPA	forelimb nail number	females	0.0 %	1.0
SHIRPA	forelimb nail number	males	0.0 %	1.0
SHIRPA	forelimb nail number	both	0.0 %	1.0
SHIRPA	forelimb nail position	females	0.0 %	1.0
SHIRPA	forelimb nail position	males	0.0 %	1.0
SHIRPA	forelimb nail position	both	0.0 %	1.0
SHIRPA	forelimb nail shape	females	0.0 %	1.0
SHIRPA	forelimb nail shape	males	0.0 %	1.0
SHIRPA	forelimb nail shape	both	0.0 %	1.0
SHIRPA	forelimbs position	females	0.0 %	1.0
SHIRPA	forelimbs position	males	0.0 %	1.0
SHIRPA	forelimbs position	both	0.0 %	1.0
SHIRPA	forelimbs shape	females	0.0 %	1.0
SHIRPA	forelimbs shape	males	0.0 %	1.0
SHIRPA	forelimbs shape	both	0.0 %	1.0
SHIRPA	forelimbs size	females	0.0 %	1.0
SHIRPA	forelimbs size	males	0.0 %	1.0
SHIRPA	forelimbs size	both	0.0 %	1.0
SHIRPA	forepaw position	females	0.0 %	1.0
SHIRPA	forepaw position	males	0.0 %	1.0
SHIRPA	forepaw position	both	0.0 %	1.0
SHIRPA	forepaw shape	females	0.0 %	1.0
SHIRPA	forepaw shape	males	0.0 %	1.0
SHIRPA	forepaw shape	both	0.0 %	1.0
SHIRPA	forepaw size	females	0.0 %	1.0
SHIRPA	forepaw size	males	0.0 %	1.0
SHIRPA	forepaw size	both	0.0 %	1.0
SHIRPA	gait (fluidity)	females	0.0 %	1.0
SHIRPA	gait (fluidity)	males	0.0 %	1.00
SHIRPA	gait (fluidity)	both	0.0 %	1.00
SHIRPA	genitalia morphology	females	0.0 %	1.00
SHIRPA	genitalia morphology	males	0.0 %	1.0
SHIRPA	genitalia morphology	both	0.0 %	1.00
SHIRPA	genitalia presence	females	0.0 %	1.0
SHIRPA	genitalia presence	males	0.0 %	1.0
SHIRPA	genitalia presence	both	0.0 %	1.0
SHIRPA	genitalia size	females	0.0 %	1.0
SHIRPA	genitalia size	males	0.0 %	1.0
SHIRPA	genitalia size	both	0.0 %	1.0
SHIRPA	head bobbing	females	0.0 %	1.0
SHIRPA	head bobbing	males	0.0 %	1.0
SHIRPA	head bobbing	both	0.0 %	1.0
SHIRPA	head morphology	females	0.0 %	1.0
SHIRPA	head morphology	males	0.0 %	1.00
SHIRPA	head morphology	both	0.0 %	1.0
SHIRPA	head size	females	0.0 %	1.0
SHIRPA	head size	males	0.0 %	1.0
SHIRPA	head size	both	0.0 %	1.00
SHIRPA	hindlimb digit number	females	1.0 %	1.00
SHIRPA	hindlimb digit number	males	0.0 %	1.0
SHIRPA	hindlimb digit number	both	0.0 %	1.00
SHIRPA	hindlimb digit position	females	0.0 %	1.0
SHIRPA	hindlimb digit position	males	0.0 %	1.0
SHIRPA	hindlimb digit position	both	0.0 %	1.0
SHIRPA	hindlimb digit shape	females	0.0 %	1.0
SHIRPA	hindlimb digit shape	males	0.0 %	1.0
SHIRPA	hindlimb digit shape	both	0.0 %	1.0
SHIRPA	hindlimb digit size	females	0.0 %	1.00
SHIRPA	hindlimb digit size	males	0.0 %	1.0
SHIRPA	hindlimb digit size	both	0.0 %	1.00
SHIRPA	hindlimb nail length	females	0.0 %	1.0
SHIRPA	hindlimb nail length	males	0.0 %	1.0
SHIRPA	hindlimb nail length	both	0.0 %	1.00
SHIRPA	hindlimb nail number	females	0.0 %	1.0
SHIRPA	hindlimb nail number	males	1.0 %	1.0
SHIRPA	hindlimb nail number	both	0.0 %	1.00
SHIRPA	hindlimb nail position	females	0.0 %	1.0
SHIRPA	hindlimb nail position	males	0.0 %	1.0
SHIRPA	hindlimb nail position	both	0.0 %	1.0
SHIRPA	hindlimb nail shape	females	0.0 %	1.0
SHIRPA	hindlimb nail shape	males	0.0 %	1.0
SHIRPA	hindlimb nail shape	both	0.0 %	1.0
SHIRPA	hindlimbs footpads	females	0.0 %	1.0
SHIRPA	hindlimbs footpads	males	0.0 %	1.0
SHIRPA	hindlimbs footpads	both	0.0 %	1.0
SHIRPA	hindlimbs position	females	0.0 %	1.0
SHIRPA	hindlimbs position	males	0.0 %	1.0
SHIRPA	hindlimbs position	both	0.0 %	1.0
SHIRPA	hindlimbs shape	females	0.0 %	1.0
SHIRPA	hindlimbs shape	males	0.0 %	1.0
SHIRPA	hindlimbs shape	both	0.0 %	1.0
SHIRPA	hindlimbs size	females	0.0 %	1.0
SHIRPA	hindlimbs size	males	0.0 %	1.0
SHIRPA	hindlimbs size	both	0.0 %	1.0
SHIRPA	hindpaw position	females	0.0 %	1.0
SHIRPA	hindpaw position	males	0.0 %	1.0
SHIRPA	hindpaw position	both	0.0 %	1.0
SHIRPA	hindpaw shape	females	0.0 %	1.0
SHIRPA	hindpaw shape	males	0.0 %	1.0
SHIRPA	hindpaw shape	both	0.0 %	1.0
SHIRPA	hindpaw size	females	0.0 %	1.0
SHIRPA	hindpaw size	males	0.0 %	1.0
SHIRPA	hindpaw size	both	0.0 %	1.0
SHIRPA	limb grasp	females	9.0 %	1.00
SHIRPA	limb grasp	males	6.0 %	1.0
SHIRPA	limb grasp	both	7.0 %	0.624
SHIRPA	lower lip morphology	females	0.0 %	1.0
SHIRPA	lower lip morphology	males	0.0 %	1.0
SHIRPA	lower lip morphology	both	0.0 %	1.0
SHIRPA	lower teeth appearance	females	0.0 %	1.0
SHIRPA	lower teeth appearance	males	0.0 %	1.00
SHIRPA	lower teeth appearance	both	0.0 %	1.00
SHIRPA	mouth morphology	females	0.0 %	1.0
SHIRPA	mouth morphology	males	0.0 %	1.00
SHIRPA	mouth morphology	both	0.0 %	1.00
SHIRPA	salivation	females	0.0 %	1.0
SHIRPA	salivation	males	0.0 %	1.0
SHIRPA	salivation	both	0.0 %	1.0
SHIRPA	skin color back paws	females	0.0 %	1.0
SHIRPA	skin color back paws	males	0.0 %	1.0
SHIRPA	skin color back paws	both	0.0 %	1.0
SHIRPA	skin color ear	females	0.0 %	1.0
SHIRPA	skin color ear	males	0.0 %	1.0
SHIRPA	skin color ear	both	0.0 %	1.0
SHIRPA	skin color front paws	females	0.0 %	1.0
SHIRPA	skin color front paws	males	0.0 %	1.0
SHIRPA	skin color front paws	both	0.0 %	1.0
SHIRPA	skin color snout	females	0.0 %	1.0
SHIRPA	skin color snout	males	0.0 %	1.0
SHIRPA	skin color snout	both	0.0 %	1.0
SHIRPA	skin color tail	females	0.0 %	1.0
SHIRPA	skin color tail	males	0.0 %	1.0
SHIRPA	skin color tail	both	0.0 %	1.0
SHIRPA	skin color whole body	females	0.0 %	1.0
SHIRPA	skin color whole body	males	0.0 %	1.0
SHIRPA	skin color whole body	both	0.0 %	1.0
SHIRPA	skin texture back paw	females	0.0 %	1.0
SHIRPA	skin texture back paw	males	0.0 %	1.0
SHIRPA	skin texture back paw	both	0.0 %	1.0
SHIRPA	skin texture ear	females	0.0 %	1.0
SHIRPA	skin texture ear	males	0.0 %	1.0
SHIRPA	skin texture ear	both	0.0 %	1.0
SHIRPA	skin texture front paws	females	0.0 %	1.0
SHIRPA	skin texture front paws	males	0.0 %	1.0
SHIRPA	skin texture front paws	both	0.0 %	1.0
SHIRPA	skin texture snout	females	0.0 %	1.0
SHIRPA	skin texture snout	males	0.0 %	1.0
SHIRPA	skin texture snout	both	0.0 %	1.0
SHIRPA	skin texture tail	females	0.0 %	1.0
SHIRPA	skin texture tail	males	0.0 %	1.0
SHIRPA	skin texture tail	both	0.0 %	1.0
SHIRPA	skin texture whole body	females	0.0 %	1.0
SHIRPA	skin texture whole body	males	0.0 %	1.00
SHIRPA	skin texture whole body	both	0.0 %	1.00
SHIRPA	snout size	females	0.0 %	1.0
SHIRPA	snout size	males	1.0 %	1.0
SHIRPA	snout size	both	0.0 %	1.0
SHIRPA	startle response	females	0.0 %	1.00
SHIRPA	startle response	males	0.0 %	1.00
SHIRPA	startle response	both	0.0 %	1.00
SHIRPA	tail curvature	females	0.0 %	1.00
SHIRPA	tail curvature	males	0.0 %	1.0
SHIRPA	tail curvature	both	0.0 %	1.0
SHIRPA	tail elevation	females	1.0 %	1.00
SHIRPA	tail elevation	males	2.0 %	1.0
SHIRPA	tail elevation	both	1.0 %	1.0
SHIRPA	tail length	females	0.0 %	1.0
SHIRPA	tail length	males	0.0 %	1.0
SHIRPA	tail length	both	0.0 %	1.00
SHIRPA	tail morphology	females	0.0 %	1.00
SHIRPA	tail morphology	males	0.0 %	1.0
SHIRPA	tail morphology	both	0.0 %	1.00
SHIRPA	tail presence	females	0.0 %	1.0
SHIRPA	tail presence	males	0.0 %	1.0
SHIRPA	tail presence	both	0.0 %	1.0
SHIRPA	tail shape	females	0.0 %	1.0
SHIRPA	tail shape	males	0.0 %	1.0
SHIRPA	tail shape	both	0.0 %	1.00
SHIRPA	tail thickness	females	0.0 %	1.0
SHIRPA	tail thickness	males	0.0 %	1.0
SHIRPA	tail thickness	both	0.0 %	1.0
SHIRPA	teeth presence	females	0.0 %	1.0
SHIRPA	teeth presence	males	0.0 %	1.00
SHIRPA	teeth presence	both	0.0 %	1.00
SHIRPA	transfer arousal	females	1.0 %	1.0
SHIRPA	transfer arousal	males	2.0 %	1.00
SHIRPA	transfer arousal	both	1.0 %	1.0
SHIRPA	tremor	females	0.0 %	1.0
SHIRPA	tremor	males	0.0 %	1.0
SHIRPA	tremor	both	0.0 %	1.00
SHIRPA	trunk curl	females	0.0 %	1.00
SHIRPA	trunk curl	males	0.0 %	1.0
SHIRPA	trunk curl	both	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	females	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	males	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	both	0.0 %	1.00
SHIRPA	upper lip morphology	females	0.0 %	1.0
SHIRPA	upper lip morphology	males	0.0 %	1.0
SHIRPA	upper lip morphology	both	0.0 %	1.0
SHIRPA	upper teeth appearance	females	0.0 %	1.0
SHIRPA	upper teeth appearance	males	0.0 %	1.0
SHIRPA	upper teeth appearance	both	0.0 %	1.00
SHIRPA	vibrissae appearance	females	2.0 %	1.0
SHIRPA	vibrissae appearance	males	1.0 %	1.0
SHIRPA	vibrissae appearance	both	1.0 %	1.0
SHIRPA	vibrissae presence	females	2.0 %	1.00
SHIRPA	vibrissae presence	males	1.0 %	1.0
SHIRPA	vibrissae presence	both	2.0 %	1.0
SHIRPA	vocalization	females	2.0 %	1.00
SHIRPA	vocalization	males	2.0 %	1.0
SHIRPA	vocalization	both	2.0 %	1.00

GENOTYPE CORRELATION PLOT

Correlate U2surp^em1(IMPC)J/Mmjax -/+ with genotype: