MPD: JaxKOMP-EAP genotype: Znfx1<sup>em1(IMPC)J</sup>/Mmjax -/-

JaxKOMP-EAP effect sizes: Znfx1^em1(IMPC)J/Mmjax -/- Gene Znfx1

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

In this plot, data points are the computed genotype effect size vs. C57BL/6NJ controls, for all measured numeric phenotypes in JaxKOMP-EAP

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Plot Options Group by Procedure Standard Error Show Effect Sizes RankZ

Significance Threshold p-Value Threshold Adjusted Unadjusted

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Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value

ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	-10.283	4.4545	-2.2370	0.308	0.0368
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	3.1736	3.8887	0.69284	0.826	0.428
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	8.9048	5.0155	1.3230	0.443	0.0976
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	1.9111	5.1189	0.18758	0.895	0.714
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	-0.038587	4.3920	-0.039264	0.997	0.993
body composition	body length	-0.0074008	0.049065	0.098363	0.961	0.881
body composition	body weight (at time of DXA)	-0.13186	0.81397	-0.010234	0.948	0.872
body composition	bone area, whole body scan, head excluded	0.37851	0.17981	1.7226	0.199	0.0438
body composition	bone mineral content of whole body scan, head excluded	0.027243	0.014397	1.7048	0.261	0.0685
body composition	bone mineral content to body weight ratio	0.0012043	0.00054821	1.7106	0.167	0.0362
body composition	bone mineral density of whole body scan, head excluded	0.00098745	0.00069584	1.0874	0.449	0.167
body composition	fat tissue mass of whole body scan, head excluded	-0.80478	0.41858	-1.4944	0.240	0.0644
body composition	fat tissue mass to body weight ratio	-0.026420	0.014306	-1.1841	0.232	0.0750
body composition	lean tissue mass of whole body scan, head excluded	0.48074	0.39826	0.81507	0.537	0.237
body composition	lean tissue mass to body weight ratio	0.021709	0.011687	1.0728	0.258	0.0734
body composition	percent fat, whole body scan, head excluded	-2.5545	1.3564	-1.2206	0.233	0.0697
body composition	ratio of soft-tissue attenuation coefficients	0.0028243	0.0015030	1.2079	0.237	0.0703
body composition	tissue area	-0.16706	0.21940	-0.37929	0.739	0.453
body composition	total tissue mass, whole body scan, head excluded	-0.23136	0.39007	-0.76106	0.756	0.558
clinical blood chemistry	alanine transaminase (plasma ALT)	7.1052	4.9819	0.55010	0.539	0.169
clinical blood chemistry	albumin (plasma Alb)	-1.0675	0.51628	-1.3174	0.282	0.0512
clinical blood chemistry	alkaline phosphatase (plasma ALP)	-6.9536	2.8515	-1.6641	0.125	0.0242
clinical blood chemistry	aspartate transaminase (plasma AST)	7.3546	6.8735	0.35767	0.617	0.297
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	-0.12466	0.14619	-0.39160	0.782	0.403
clinical blood chemistry	blood urea nitrogen (BUN)	-3.4245	1.6539	-1.3282	0.214	0.0509
clinical blood chemistry	calcium (plasma Ca)	-0.10238	0.087139	-0.36101	0.481	0.253
clinical blood chemistry	creatinine (plasma)	-0.033465	0.020785	-0.64340	0.333	0.122
clinical blood chemistry	glucose (plasma GLU, no fast)	-28.131	13.923	-0.71402	0.171	0.0563
clinical blood chemistry	HDL cholesterol (plasma HDL)	0.95911	2.7840	-0.095792	0.902	0.734
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	0.015887	0.014141	0.74640	0.611	0.274
clinical blood chemistry	phosphorus (plasma phosphate)	0.24355	0.65663	0.34518	0.863	0.714
clinical blood chemistry	total bilirubin (plasma TBIL)	0.0069625	0.0058440	0.47582	0.592	0.247
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	-0.78611	3.8724	-0.38234	0.941	0.841
clinical blood chemistry	total protein (plasma TP)	-1.2345	0.65961	-1.0301	0.310	0.0753
clinical blood chemistry	triglyceride (plasma TG, no fast)	-47.131	20.083	-1.7317	0.175	0.0293
ERG v2.0	left eye a-wave amplitude (Photopic)	0.16622	1.6907	0.11016	0.961	0.923
ERG v2.0	left eye a-wave amplitude (Scotopic)	-26.924	21.984	-0.95721	0.615	0.242
ERG v2.0	left eye a-wave implicit timing (Photopic)	-2.2790	1.7230	-0.98368	0.752	0.211
ERG v2.0	left eye a-wave implicit timing (Scotopic)	0.56176	0.59766	0.50432	0.773	0.364
ERG v2.0	left eye b-wave amplitude (Photopic)	12.603	6.0868	0.81989	0.372	0.0589
ERG v2.0	left eye b-wave amplitude (Scotopic)	52.607	42.950	0.87345	0.648	0.242
ERG v2.0	left eye b-wave implicit timing (Photopic)	-4.4692	3.8258	-0.80460	0.619	0.264
ERG v2.0	left eye b-wave implicit timing (Scotopic)	1.2736	7.2630	0.18561	0.974	0.864
ERG v2.0	left eye c-wave amplitude (Scotopic)	32.343	36.849	0.84319	0.739	0.396
ERG v2.0	left eye c-wave implicit timing (Scotopic)	54.471	46.519	0.39481	0.668	0.263
ERG v2.0	left eye FO-like wave amplitude (Scotopic)	-91.086	57.759	-1.3147	0.562	0.141
ERG v2.0	left eye FO-like wave implicit timing (Scotopic)	-110.96	87.508	-0.21372	0.750	0.227
ERG v2.0	right eye a-wave amplitude (Photopic)	-2.3382	1.8862	-0.70236	0.710	0.237
ERG v2.0	right eye a-wave amplitude (Scotopic)	-36.982	20.736	-1.4584	0.521	0.0979
ERG v2.0	right eye a-wave implicit timing (Photopic)	-0.32318	1.4717	-0.15208	0.954	0.830
ERG v2.0	right eye a-wave implicit timing (Scotopic)	-0.14067	0.50194	-0.077374	0.932	0.784
ERG v2.0	right eye b-wave amplitude (Photopic)	12.477	5.5841	0.85898	0.348	0.0436
ERG v2.0	right eye b-wave amplitude (Scotopic)	85.287	43.407	1.4745	0.476	0.0712
ERG v2.0	right eye b-wave implicit timing (Photopic)	-5.9565	2.9582	-1.2168	0.366	0.0652
ERG v2.0	right eye b-wave implicit timing (Scotopic)	4.5898	5.9065	0.56779	0.832	0.451
ERG v2.0	right eye c-wave amplitude (Scotopic)	57.793	34.441	1.3413	0.540	0.117
ERG v2.0	right eye c-wave implicit timing (Scotopic)	10.797	47.474	0.20246	0.949	0.824
ERG v2.0	right eye FO-like wave amplitude (Scotopic)	-61.543	48.348	-1.0886	0.616	0.225
ERG v2.0	right eye FO-like wave implicit timing (Scotopic)	-7.1170	219.68	0.18800	0.985	0.975
glucose tolerance test	amount glucose injected	0.34562	5.3802	0.47440	0.982	0.955
glucose tolerance test	plasma glucose, 0min	-2.5501	7.9929	-0.48202	0.889	0.780
glucose tolerance test	plasma glucose, 15min	11.556	82.162	0.45140	0.964	0.901
glucose tolerance test	plasma glucose, 30min	25.077	36.750	0.86374	0.807	0.565
glucose tolerance test	plasma glucose, 60min	-9.5000	20.082	-0.28809	0.883	0.683
glucose tolerance test	plasma glucose, 120min	10.064	16.133	0.57518	0.823	0.596
grip strength	body weight (at time of grip strength test)	0.095065	0.43817	0.29583	0.905	0.829
grip strength	forelimb and hindlimb grip strength (mean of trials), average	-20.882	4.8897	-1.1696	0.00278	0.000121
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	-0.84727	0.22328	-1.0141	0.00782	0.000503
grip strength	forelimb and hindlimb grip strength by trial, trial1	-23.064	7.7922	-1.2902	0.0562	0.00515
grip strength	forelimb and hindlimb grip strength by trial, trial2	-16.042	6.0803	-0.77165	0.0890	0.0119
grip strength	forelimb and hindlimb grip strength by trial, trial3	-22.848	5.3205	-1.2200	0.00522	0.000112
grip strength	forelimb grip strength (mean of trials), average	-20.237	3.3739	-1.9325	0.000150	5.21e-7
grip strength	forelimb grip strength (mean of trials), average normalized to bw	-0.87954	0.14780	-1.7183	0.000209	6.06e-7
grip strength	forelimb grip strength by trial, trial1	-19.123	4.1001	-1.7577	0.00423	0.0000343
grip strength	forelimb grip strength by trial, trial2	-21.658	4.7182	-1.8622	0.00433	0.0000452
grip strength	forelimb grip strength by trial, trial3	-18.586	4.6124	-1.5624	0.0127	0.000243
heart weight	heart weight, normalized to body weight	0.23931	0.12282	0.37987	0.200	0.0622
heart weight	heart weight, weight	5.0123	3.0099	0.27433	0.282	0.108
hematology	basophil differential (percent of total WBC)	0.014881	0.040498	0.26527	0.921	0.717
hematology	calculated hemoglobin (cHGB)	0.35119	0.28962	0.84509	0.522	0.239
hematology	eosinophil differential (percent of total WBC)	0.22158	0.27918	0.70441	0.789	0.436
hematology	hematocrit (HCT)	-0.10510	0.59090	-0.47515	0.933	0.861
hematology	hemoglobin concentration distribution width (HDW)	0.12109	0.023563	2.1457	0.00288	0.0000500
hematology	large unstained cells (percent of total WBC)	-1.1159	0.17289	-2.8659	0.00109	0.00000347
hematology	lymphocyte differential (percent of total WBC)	1.6609	1.6705	0.59833	0.582	0.331
hematology	mean corpuscular hemoglobin (CHr)	-0.13902	0.068945	-1.1101	0.199	0.0574
hematology	mean platelet volume (MPV)	0.38003	0.13508	1.4713	0.0564	0.0104
hematology	mean RBC corpuscular hemoglobin (MCH)	0.092553	0.14112	0.33264	0.797	0.519
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	0.61824	0.31538	1.1685	0.345	0.0634
hematology	mean RBC corpuscular volume (MCV)	-1.0736	0.20696	-1.5325	0.000988	0.0000447
hematology	measured hemoglobin (mHGB)	0.23994	0.27340	0.39351	0.671	0.390
hematology	monocyte differential (percent of total WBC)	-1.4508	0.39457	-2.0615	0.0744	0.00140
hematology	neutrophil differential (percent of total WBC)	-0.33133	1.4017	-0.14539	0.904	0.815
hematology	platelet count (PLT; units per volume x 10³)	-21.214	50.463	-0.24714	0.875	0.679
hematology	RBC corpuscular distribution width (RDW)	1.2332	0.27223	2.1764	0.00743	0.000183
hematology	RBC corpuscular hemoglobin concentration mean (CHCM)	0.64016	0.20695	1.4748	0.0491	0.00573
hematology	red blood cell count (RBC; per volume x 10⁶)	0.20347	0.13645	0.55064	0.407	0.151
hematology	reticulocyte count (Retic; units per volume x 10⁹)	-2.9847	22.703	-0.037780	0.974	0.897
hematology	reticulocyte differential (percent of total RBC)	-0.044974	0.21288	0.026192	0.934	0.835
hematology	white blood cell count (WBC; units per volume x 10³)	-1.2957	0.99174	-0.71362	0.409	0.206
light / dark	latency to enter dark zone, 20 min test	87.934	67.498	1.3673	0.630	0.205
light / dark	number of transitions between light and dark zones, 20 min test	-1.3575	8.1429	-0.0027040	0.948	0.869
light / dark	percentage of total time in dark zone, 20 min test	-5.9720	5.0813	-0.91891	0.615	0.251
light / dark	percentage of total time in light zone, 20 min test	5.9720	5.0813	0.91479	0.616	0.251
light / dark	time mobile in dark zone, 20 min test	-15.708	15.591	-1.0252	0.615	0.323
light / dark	time mobile in light zone, 20 min test	12.199	13.061	0.49698	0.623	0.359
light / dark	time spent in dark zone, 20 min test	-136.94	74.143	-1.6177	0.434	0.0766
light / dark	time spent in light zone, 20 min test	136.94	74.143	1.6177	0.434	0.0766
open field	average speed in center of arena, 20 min test	-0.18498	0.41785	-0.41360	0.868	0.660
open field	average speed in periphery of arena, 20 min test	-0.099897	0.13451	-0.90735	0.687	0.462
open field	distance traveled habituation ratio, 20 min test	-6.7105	6.6480	-0.55249	0.638	0.319
open field	distance traveled in center of arena, 20 min test	93.541	104.98	0.26696	0.629	0.378
open field	distance traveled in periphery of arena, 20 min test	-105.11	151.25	-0.85007	0.714	0.491
open field	distance traveled slope, 20 min test	-5.6303	6.1960	-0.46536	0.684	0.369
open field	distance traveled, 20 min test, 1st 5min	55.875	66.954	0.10019	0.647	0.409
open field	distance traveled, 20 min test, 2nd 5min	-35.736	50.663	-0.91345	0.708	0.485
open field	distance traveled, 20 min test, 3rd 5min	1.6109	58.975	-0.40922	0.997	0.978
open field	distance traveled, 20 min test, 4th 5min	-14.510	55.654	-0.63909	0.909	0.796
open field	number of clockwise revolution episodes, 20 min test	-0.010485	1.1713	-0.41311	0.997	0.993
open field	number of counter-clockwise revolution episodes, 20 min test	0.65519	1.2006	-0.085358	0.787	0.588
open field	number of rears in 5 min bins, 20 min test, 1st 5min	1.8295	1.6495	0.29576	0.542	0.274
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	2.3397	2.3454	0.24891	0.610	0.324
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	2.7262	2.5607	0.34008	0.567	0.293
open field	number of rears in 5 min bins, 20 min test, 4th 5min	0.42735	2.8274	-0.26974	0.943	0.881
open field	percentage of total time in center of arena, 20 min test	1.6681	4.8911	0.18977	0.897	0.735
open field	percentage of total time in center of arena, slope, 20 min test	1.2237	1.7189	0.81963	0.852	0.481
open field	percentage of total time in center, habituation ratio, 20 min test	0.67342	1.9012	0.47887	0.930	0.725
open field	percentage of total time in corners of arena, 20 min test	-4.7414	5.3132	-0.57611	0.673	0.378
open field	percentage of total time in corners, habituation ratio, 20 min test	-0.85411	2.2136	-0.70300	0.946	0.702
open field	percentage of total time in corners, slope, 20 min test	-0.92198	2.1376	-0.74665	0.931	0.669
open field	permanence time in center of arena, 20 min test	20.034	58.693	0.18977	0.898	0.735
open field	permanence time in corners of arena, 20 min test	-56.896	63.757	-0.57611	0.673	0.378
open field	permanence time in periphery of arena, 20 min test	-20.024	58.694	-0.19113	0.898	0.735
open field	total distance traveled, 20 min test	-23.272	199.81	-0.56820	0.954	0.908
open field	total number of rears, 20 min test	7.9785	8.3432	0.20894	0.599	0.345
open field	whole arena average speed, 20 min test	-0.019403	0.16636	-0.56820	0.954	0.908
open field	whole arena resting time, 20 min test	-36.012	35.008	-0.44452	0.516	0.310
open field	whole arena time spent mobile, 20 min test	-2.6335	18.527	-0.65731	0.938	0.888
open field	whole arena time spent vertical, 20 min test	4.7257	6.1324	0.26974	0.731	0.445
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	-1.1271	1.2097	-0.29066	0.655	0.357
startle / PPI	average baseline movement during background noise	2.4569	1.0853	1.3833	0.459	0.0310
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	-0.033143	0.063843	-0.39917	0.825	0.607
startle / PPI	average of each corrected percent pre-pulse inhibition value	-0.042320	0.060423	-0.48789	0.786	0.489
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	1.3947	7.5654	0.22106	0.992	0.855
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-3.3271	6.6331	-0.38857	0.857	0.620
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-6.9149	6.0016	-0.74710	0.557	0.258
startle / PPI	average startle response to full pulse (120 dB)	-64.530	43.550	-0.92827	0.360	0.149
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-56.077	46.500	-0.82733	0.478	0.237
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-31.111	37.604	-0.45132	0.620	0.415
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-11.450	30.322	-0.097533	0.832	0.708
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	-0.10198	2.0843	0.0077063	0.994	0.961
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	-0.74529	1.8986	-0.49837	0.948	0.697
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	-0.35358	2.2358	-0.36151	0.972	0.875
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.0020888	0.085369	0.052567	0.998	0.981
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.050922	0.069191	-0.50375	0.747	0.467
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-0.085822	0.069164	-0.83286	0.484	0.224
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	-66.986	43.632	-0.96556	0.338	0.135
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	-56.789	47.189	-0.83326	0.474	0.238
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	-30.366	37.668	-0.43432	0.627	0.427
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	-11.611	30.325	-0.089090	0.824	0.705
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.00031302	0.095948	0.037139	0.999	0.997
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.037327	0.072686	-0.37147	0.823	0.611
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-0.065789	0.071668	-0.66397	0.628	0.366
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	-230.19	163.56	-0.92827	0.386	0.170
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	-186.40	172.44	-0.76575	0.527	0.288
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	-108.96	143.50	-0.41286	0.651	0.454
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	-40.895	113.89	-0.060987	0.833	0.722
startle / PPI	maximum baseline movement during background noise	7.2776	3.3617	1.6002	0.439	0.0385
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	1.3313	8.6725	0.18530	0.997	0.879
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-2.3546	7.1090	-0.27598	0.902	0.743
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-5.1802	6.4998	-0.62134	0.706	0.432
startle / PPI	maximum startle response to full pulse (120 dB)	-222.91	163.85	-0.89222	0.404	0.184
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-185.57	171.04	-0.76575	0.528	0.287
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-109.20	143.51	-0.42510	0.655	0.453
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-41.708	114.01	-0.073626	0.836	0.717
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	-0.58948	4.1500	-0.062391	0.975	0.888
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	-0.23944	4.0100	-0.060987	0.996	0.953
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	-2.1001	4.7975	-0.60612	0.880	0.665

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

In this plot, data points are the computed genotype effect % vs. C57BL/6NJ controls, for all measured categorical phenotypes in JaxKOMP-EAP

Dimensions Width: × Height: px

Plot Options Group by Procedure

Include Sexes Data Both Females Males

Significance Threshold p-Value Threshold

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Procedure	JaxKOMP-EAP Trait	Sex	Trait Effect	P-value

eye morphology	anterior chamber depth	females	1.0 %	1.0
eye morphology	anterior chamber depth	males	0.0 %	1.0
eye morphology	anterior chamber depth	both	1.0 %	1.0
eye morphology	bulging eye	females	1.0 %	1.0
eye morphology	bulging eye	males	0.0 %	1.0
eye morphology	bulging eye	both	1.0 %	1.00
eye morphology	cornea	females	4.0 %	1.0
eye morphology	cornea	males	2.0 %	1.0
eye morphology	cornea	both	3.0 %	1.00
eye morphology	cornea opacity	females	5.0 %	1.00
eye morphology	cornea opacity	males	1.0 %	1.0
eye morphology	cornea opacity	both	3.0 %	1.0
eye morphology	cornea vascularization	females	3.0 %	1.0
eye morphology	cornea vascularization	males	1.0 %	1.0
eye morphology	cornea vascularization	both	2.0 %	1.0
eye morphology	corneal deposits	females	2.0 %	1.0
eye morphology	corneal deposits	males	1.0 %	1.0
eye morphology	corneal deposits	both	1.0 %	1.00
eye morphology	corneal mineralization	females	2.0 %	1.0
eye morphology	corneal mineralization	males	1.0 %	1.0
eye morphology	corneal mineralization	both	1.0 %	1.0
eye morphology	corneal scleralization	females	3.0 %	1.00
eye morphology	corneal scleralization	males	1.0 %	1.0
eye morphology	corneal scleralization	both	2.0 %	1.0
eye morphology	corneal ulcer	females	1.0 %	1.0
eye morphology	corneal ulcer	males	1.0 %	1.0
eye morphology	corneal ulcer	both	1.0 %	1.0
eye morphology	eye closure	females	1.0 %	1.00
eye morphology	eye closure	males	0.0 %	1.0
eye morphology	eye closure	both	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	females	2.0 %	1.00
eye morphology	eye hemorrhage or blood presence	males	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	both	1.0 %	1.0
eye morphology	eyelid morphology	females	1.0 %	1.0
eye morphology	eyelid morphology	males	0.0 %	1.0
eye morphology	eyelid morphology	both	1.0 %	1.0
eye morphology	eyes (present, absent)	females	1.0 %	1.0
eye morphology	eyes (present, absent)	males	0.0 %	1.0
eye morphology	eyes (present, absent)	both	0.0 %	1.0
eye morphology	fusion between cornea and lens	females	4.0 %	1.00
eye morphology	fusion between cornea and lens	males	2.0 %	1.0
eye morphology	fusion between cornea and lens	both	3.0 %	1.0
eye morphology	iris pigmentation	females	2.0 %	1.0
eye morphology	iris pigmentation	males	1.0 %	1.0
eye morphology	iris pigmentation	both	2.0 %	1.0
eye morphology	iris transillumination	females	2.0 %	1.00
eye morphology	iris transillumination	males	1.0 %	1.00
eye morphology	iris transillumination	both	1.0 %	1.00
eye morphology	irispupil	females	4.0 %	1.00
eye morphology	irispupil	males	3.0 %	1.0
eye morphology	irispupil	both	3.0 %	1.0
eye morphology	lacrimation	females	3.0 %	1.0
eye morphology	lacrimation	males	2.0 %	1.0
eye morphology	lacrimation	both	3.0 %	1.0
eye morphology	lens	females	10.0 %	1.00
eye morphology	lens	males	8.0 %	1.00
eye morphology	lens	both	9.0 %	1.0
eye morphology	lens opacity	females	11.0 %	0.316
eye morphology	lens opacity	males	6.0 %	1.00
eye morphology	lens opacity	both	5.0 %	0.441
eye morphology	narrow eye opening	females	2.0 %	1.0
eye morphology	narrow eye opening	males	1.0 %	1.0
eye morphology	narrow eye opening	both	1.0 %	1.00
eye morphology	optic disc	females	4.0 %	1.00
eye morphology	optic disc	males	2.0 %	1.00
eye morphology	optic disc	both	3.0 %	1.00
eye morphology	persistence of hyaloid vascular system	females	14.0 %	1.0
eye morphology	persistence of hyaloid vascular system	males	5.0 %	1.0
eye morphology	persistence of hyaloid vascular system	both	9.0 %	1.00
eye morphology	pupil dilation	females	2.0 %	1.0
eye morphology	pupil dilation	males	1.0 %	1.00
eye morphology	pupil dilation	both	2.0 %	1.0
eye morphology	pupil light response	females	2.0 %	1.00
eye morphology	pupil light response	males	1.0 %	1.0
eye morphology	pupil light response	both	2.0 %	1.0
eye morphology	pupil position	females	4.0 %	1.00
eye morphology	pupil position	males	3.0 %	1.0
eye morphology	pupil position	both	4.0 %	1.0
eye morphology	pupil shape	females	3.0 %	1.00
eye morphology	pupil shape	males	2.0 %	1.0
eye morphology	pupil shape	both	3.0 %	1.0
eye morphology	retina	females	10.0 %	0.560
eye morphology	retina	males	9.0 %	0.557
eye morphology	retina	both	3.0 %	0.693
eye morphology	retinal blood vessels	females	4.0 %	1.0
eye morphology	retinal blood vessels	males	2.0 %	1.0
eye morphology	retinal blood vessels	both	3.0 %	1.0
eye morphology	retinal blood vessels pattern	females	5.0 %	1.0
eye morphology	retinal blood vessels pattern	males	2.0 %	1.00
eye morphology	retinal blood vessels pattern	both	4.0 %	1.00
eye morphology	retinal blood vessels structure	females	4.0 %	1.00
eye morphology	retinal blood vessels structure	males	2.0 %	1.0
eye morphology	retinal blood vessels structure	both	3.0 %	1.0
eye morphology	retinal pigmentation	females	12.0 %	1.0
eye morphology	retinal pigmentation	males	14.0 %	1.0
eye morphology	retinal pigmentation	both	13.0 %	1.0
eye morphology	retinal structure	females	4.0 %	1.00
eye morphology	retinal structure	males	2.0 %	1.00
eye morphology	retinal structure	both	3.0 %	1.00
eye morphology	synechia	females	4.0 %	1.0
eye morphology	synechia	males	2.0 %	1.00
eye morphology	synechia	both	3.0 %	1.00
eye morphology	vitreous	females	4.0 %	1.00
eye morphology	vitreous	males	2.0 %	1.0
eye morphology	vitreous	both	3.0 %	1.0
SHIRPA	activity body position	females	1.0 %	1.0
SHIRPA	activity body position	males	2.0 %	1.0
SHIRPA	activity body position	both	1.0 %	1.00
SHIRPA	aggression	females	0.0 %	1.00
SHIRPA	aggression	males	1.0 %	1.0
SHIRPA	aggression	both	1.0 %	1.00
SHIRPA	body length	females	0.0 %	1.0
SHIRPA	body length	males	0.0 %	1.0
SHIRPA	body length	both	0.0 %	1.0
SHIRPA	body position	females	0.0 %	1.0
SHIRPA	body position	males	1.0 %	1.0
SHIRPA	body position	both	0.0 %	1.00
SHIRPA	body thickness	females	1.0 %	1.0
SHIRPA	body thickness	males	0.0 %	1.0
SHIRPA	body thickness	both	0.0 %	1.00
SHIRPA	coat color abdomen	females	3.0 %	1.00
SHIRPA	coat color abdomen	males	4.0 %	1.00
SHIRPA	coat color abdomen	both	4.0 %	1.00
SHIRPA	coat color back	females	0.0 %	1.0
SHIRPA	coat color back	males	0.0 %	1.0
SHIRPA	coat color back	both	0.0 %	1.00
SHIRPA	coat color head	females	0.0 %	1.0
SHIRPA	coat color head	males	0.0 %	1.0
SHIRPA	coat color head	both	0.0 %	1.0
SHIRPA	coat color pattern abdomen	females	12.0 %	0.0461
SHIRPA	coat color pattern abdomen	males	1.0 %	1.0
SHIRPA	coat color pattern abdomen	both	6.0 %	0.0902
SHIRPA	coat color pattern back	females	0.0 %	1.0
SHIRPA	coat color pattern back	males	0.0 %	1.0
SHIRPA	coat color pattern back	both	0.0 %	1.00
SHIRPA	coat color pattern head	females	0.0 %	1.0
SHIRPA	coat color pattern head	males	0.0 %	1.00
SHIRPA	coat color pattern head	both	0.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	females	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	males	41.0 %	0.000549
SHIRPA	coat hair abdomen texture appearance	both	18.0 %	0.00334
SHIRPA	coat hair back texture appearance	females	0.0 %	1.0
SHIRPA	coat hair back texture appearance	males	0.0 %	1.0
SHIRPA	coat hair back texture appearance	both	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	females	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	males	42.0 %	0.0000564
SHIRPA	coat hair distribution abdomen	both	19.0 %	0.000136
SHIRPA	coat hair distribution back	females	0.0 %	1.0
SHIRPA	coat hair distribution back	males	0.0 %	1.0
SHIRPA	coat hair distribution back	both	0.0 %	1.00
SHIRPA	coat hair distribution head	females	1.0 %	1.00
SHIRPA	coat hair distribution head	males	1.0 %	1.0
SHIRPA	coat hair distribution head	both	1.0 %	1.0
SHIRPA	coat hair head texture appearance	females	0.0 %	1.00
SHIRPA	coat hair head texture appearance	males	0.0 %	1.0
SHIRPA	coat hair head texture appearance	both	0.0 %	1.0
SHIRPA	contact righting	females	5.0 %	1.0
SHIRPA	contact righting	males	5.0 %	1.00
SHIRPA	contact righting	both	5.0 %	1.00
SHIRPA	ear morphology	females	0.0 %	1.0
SHIRPA	ear morphology	males	0.0 %	1.0
SHIRPA	ear morphology	both	0.0 %	1.0
SHIRPA	fat distribution	females	0.0 %	1.0
SHIRPA	fat distribution	males	0.0 %	1.0
SHIRPA	fat distribution	both	0.0 %	1.0
SHIRPA	forelimb digit number	females	0.0 %	1.00
SHIRPA	forelimb digit number	males	0.0 %	1.0
SHIRPA	forelimb digit number	both	0.0 %	1.0
SHIRPA	forelimb digit position	females	0.0 %	1.0
SHIRPA	forelimb digit position	males	0.0 %	1.0
SHIRPA	forelimb digit position	both	0.0 %	1.0
SHIRPA	forelimb digit shape	females	0.0 %	1.0
SHIRPA	forelimb digit shape	males	0.0 %	1.0
SHIRPA	forelimb digit shape	both	0.0 %	1.0
SHIRPA	forelimb digit size	females	0.0 %	1.0
SHIRPA	forelimb digit size	males	0.0 %	1.0
SHIRPA	forelimb digit size	both	0.0 %	1.0
SHIRPA	forelimb footpads	females	0.0 %	1.0
SHIRPA	forelimb footpads	males	0.0 %	1.0
SHIRPA	forelimb footpads	both	0.0 %	1.0
SHIRPA	forelimb nail length	females	0.0 %	1.0
SHIRPA	forelimb nail length	males	0.0 %	1.0
SHIRPA	forelimb nail length	both	0.0 %	1.0
SHIRPA	forelimb nail number	females	0.0 %	1.0
SHIRPA	forelimb nail number	males	0.0 %	1.0
SHIRPA	forelimb nail number	both	0.0 %	1.0
SHIRPA	forelimb nail position	females	0.0 %	1.0
SHIRPA	forelimb nail position	males	0.0 %	1.0
SHIRPA	forelimb nail position	both	0.0 %	1.0
SHIRPA	forelimb nail shape	females	0.0 %	1.0
SHIRPA	forelimb nail shape	males	0.0 %	1.0
SHIRPA	forelimb nail shape	both	0.0 %	1.0
SHIRPA	forelimbs position	females	0.0 %	1.0
SHIRPA	forelimbs position	males	0.0 %	1.0
SHIRPA	forelimbs position	both	0.0 %	1.0
SHIRPA	forelimbs shape	females	0.0 %	1.0
SHIRPA	forelimbs shape	males	0.0 %	1.0
SHIRPA	forelimbs shape	both	0.0 %	1.0
SHIRPA	forelimbs size	females	0.0 %	1.0
SHIRPA	forelimbs size	males	0.0 %	1.00
SHIRPA	forelimbs size	both	0.0 %	1.0
SHIRPA	forepaw position	females	0.0 %	1.0
SHIRPA	forepaw position	males	0.0 %	1.0
SHIRPA	forepaw position	both	0.0 %	1.0
SHIRPA	forepaw shape	females	0.0 %	1.0
SHIRPA	forepaw shape	males	0.0 %	1.0
SHIRPA	forepaw shape	both	0.0 %	1.0
SHIRPA	forepaw size	females	0.0 %	1.0
SHIRPA	forepaw size	males	0.0 %	1.0
SHIRPA	forepaw size	both	0.0 %	1.0
SHIRPA	gait (fluidity)	females	0.0 %	1.0
SHIRPA	gait (fluidity)	males	0.0 %	1.0
SHIRPA	gait (fluidity)	both	0.0 %	1.0
SHIRPA	genitalia morphology	females	0.0 %	1.00
SHIRPA	genitalia morphology	males	0.0 %	1.0
SHIRPA	genitalia morphology	both	0.0 %	1.00
SHIRPA	genitalia presence	females	0.0 %	1.0
SHIRPA	genitalia presence	males	0.0 %	1.0
SHIRPA	genitalia presence	both	0.0 %	1.0
SHIRPA	genitalia size	females	0.0 %	1.0
SHIRPA	genitalia size	males	0.0 %	1.00
SHIRPA	genitalia size	both	0.0 %	1.00
SHIRPA	head bobbing	females	0.0 %	1.0
SHIRPA	head bobbing	males	0.0 %	1.0
SHIRPA	head bobbing	both	0.0 %	1.0
SHIRPA	head morphology	females	0.0 %	1.0
SHIRPA	head morphology	males	0.0 %	1.0
SHIRPA	head morphology	both	0.0 %	1.0
SHIRPA	head size	females	0.0 %	1.0
SHIRPA	head size	males	0.0 %	1.00
SHIRPA	head size	both	0.0 %	1.0
SHIRPA	hindlimb digit number	females	1.0 %	1.00
SHIRPA	hindlimb digit number	males	0.0 %	1.0
SHIRPA	hindlimb digit number	both	0.0 %	1.0
SHIRPA	hindlimb digit position	females	0.0 %	1.0
SHIRPA	hindlimb digit position	males	0.0 %	1.0
SHIRPA	hindlimb digit position	both	0.0 %	1.0
SHIRPA	hindlimb digit shape	females	0.0 %	1.0
SHIRPA	hindlimb digit shape	males	0.0 %	1.0
SHIRPA	hindlimb digit shape	both	0.0 %	1.00
SHIRPA	hindlimb digit size	females	0.0 %	1.00
SHIRPA	hindlimb digit size	males	0.0 %	1.00
SHIRPA	hindlimb digit size	both	0.0 %	1.00
SHIRPA	hindlimb nail length	females	0.0 %	1.0
SHIRPA	hindlimb nail length	males	0.0 %	1.00
SHIRPA	hindlimb nail length	both	0.0 %	1.0
SHIRPA	hindlimb nail number	females	0.0 %	1.0
SHIRPA	hindlimb nail number	males	1.0 %	1.00
SHIRPA	hindlimb nail number	both	0.0 %	1.0
SHIRPA	hindlimb nail position	females	0.0 %	1.0
SHIRPA	hindlimb nail position	males	0.0 %	1.0
SHIRPA	hindlimb nail position	both	0.0 %	1.0
SHIRPA	hindlimb nail shape	females	0.0 %	1.0
SHIRPA	hindlimb nail shape	males	0.0 %	1.0
SHIRPA	hindlimb nail shape	both	0.0 %	1.0
SHIRPA	hindlimbs footpads	females	0.0 %	1.0
SHIRPA	hindlimbs footpads	males	0.0 %	1.0
SHIRPA	hindlimbs footpads	both	0.0 %	1.0
SHIRPA	hindlimbs position	females	0.0 %	1.0
SHIRPA	hindlimbs position	males	0.0 %	1.0
SHIRPA	hindlimbs position	both	0.0 %	1.0
SHIRPA	hindlimbs shape	females	0.0 %	1.0
SHIRPA	hindlimbs shape	males	0.0 %	1.0
SHIRPA	hindlimbs shape	both	0.0 %	1.0
SHIRPA	hindlimbs size	females	0.0 %	1.0
SHIRPA	hindlimbs size	males	0.0 %	1.0
SHIRPA	hindlimbs size	both	0.0 %	1.0
SHIRPA	hindpaw position	females	0.0 %	1.0
SHIRPA	hindpaw position	males	0.0 %	1.0
SHIRPA	hindpaw position	both	0.0 %	1.0
SHIRPA	hindpaw shape	females	0.0 %	1.0
SHIRPA	hindpaw shape	males	0.0 %	1.0
SHIRPA	hindpaw shape	both	0.0 %	1.0
SHIRPA	hindpaw size	females	0.0 %	1.0
SHIRPA	hindpaw size	males	0.0 %	1.0
SHIRPA	hindpaw size	both	0.0 %	1.0
SHIRPA	limb grasp	females	9.0 %	1.00
SHIRPA	limb grasp	males	6.0 %	1.0
SHIRPA	limb grasp	both	7.0 %	0.620
SHIRPA	lower lip morphology	females	0.0 %	1.0
SHIRPA	lower lip morphology	males	0.0 %	1.0
SHIRPA	lower lip morphology	both	0.0 %	1.0
SHIRPA	lower teeth appearance	females	0.0 %	1.0
SHIRPA	lower teeth appearance	males	0.0 %	1.0
SHIRPA	lower teeth appearance	both	0.0 %	1.0
SHIRPA	mouth morphology	females	0.0 %	1.0
SHIRPA	mouth morphology	males	0.0 %	1.0
SHIRPA	mouth morphology	both	0.0 %	1.0
SHIRPA	salivation	females	0.0 %	1.0
SHIRPA	salivation	males	0.0 %	1.0
SHIRPA	salivation	both	0.0 %	1.0
SHIRPA	skin color back paws	females	0.0 %	1.0
SHIRPA	skin color back paws	males	0.0 %	1.0
SHIRPA	skin color back paws	both	0.0 %	1.0
SHIRPA	skin color ear	females	0.0 %	1.0
SHIRPA	skin color ear	males	0.0 %	1.0
SHIRPA	skin color ear	both	0.0 %	1.0
SHIRPA	skin color front paws	females	0.0 %	1.0
SHIRPA	skin color front paws	males	0.0 %	1.0
SHIRPA	skin color front paws	both	0.0 %	1.0
SHIRPA	skin color snout	females	0.0 %	1.0
SHIRPA	skin color snout	males	0.0 %	1.0
SHIRPA	skin color snout	both	0.0 %	1.0
SHIRPA	skin color tail	females	0.0 %	1.0
SHIRPA	skin color tail	males	0.0 %	1.0
SHIRPA	skin color tail	both	0.0 %	1.0
SHIRPA	skin color whole body	females	0.0 %	1.0
SHIRPA	skin color whole body	males	0.0 %	1.0
SHIRPA	skin color whole body	both	0.0 %	1.0
SHIRPA	skin texture back paw	females	0.0 %	1.0
SHIRPA	skin texture back paw	males	0.0 %	1.0
SHIRPA	skin texture back paw	both	0.0 %	1.0
SHIRPA	skin texture ear	females	0.0 %	1.0
SHIRPA	skin texture ear	males	0.0 %	1.0
SHIRPA	skin texture ear	both	0.0 %	1.0
SHIRPA	skin texture front paws	females	0.0 %	1.0
SHIRPA	skin texture front paws	males	0.0 %	1.0
SHIRPA	skin texture front paws	both	0.0 %	1.0
SHIRPA	skin texture snout	females	0.0 %	1.0
SHIRPA	skin texture snout	males	0.0 %	1.0
SHIRPA	skin texture snout	both	0.0 %	1.0
SHIRPA	skin texture tail	females	0.0 %	1.0
SHIRPA	skin texture tail	males	0.0 %	1.0
SHIRPA	skin texture tail	both	0.0 %	1.0
SHIRPA	skin texture whole body	females	0.0 %	1.0
SHIRPA	skin texture whole body	males	0.0 %	1.0
SHIRPA	skin texture whole body	both	0.0 %	1.00
SHIRPA	snout size	females	0.0 %	1.0
SHIRPA	snout size	males	1.0 %	1.0
SHIRPA	snout size	both	0.0 %	1.0
SHIRPA	startle response	females	0.0 %	1.00
SHIRPA	startle response	males	0.0 %	1.00
SHIRPA	startle response	both	0.0 %	1.0
SHIRPA	tail curvature	females	0.0 %	1.00
SHIRPA	tail curvature	males	0.0 %	1.0
SHIRPA	tail curvature	both	0.0 %	1.00
SHIRPA	tail elevation	females	1.0 %	1.00
SHIRPA	tail elevation	males	2.0 %	1.0
SHIRPA	tail elevation	both	1.0 %	1.0
SHIRPA	tail length	females	0.0 %	1.0
SHIRPA	tail length	males	0.0 %	1.00
SHIRPA	tail length	both	0.0 %	1.0
SHIRPA	tail morphology	females	0.0 %	1.00
SHIRPA	tail morphology	males	0.0 %	1.00
SHIRPA	tail morphology	both	0.0 %	1.00
SHIRPA	tail presence	females	0.0 %	1.0
SHIRPA	tail presence	males	0.0 %	1.0
SHIRPA	tail presence	both	0.0 %	1.0
SHIRPA	tail shape	females	0.0 %	1.0
SHIRPA	tail shape	males	0.0 %	1.0
SHIRPA	tail shape	both	0.0 %	1.0
SHIRPA	tail thickness	females	0.0 %	1.0
SHIRPA	tail thickness	males	0.0 %	1.0
SHIRPA	tail thickness	both	0.0 %	1.0
SHIRPA	teeth presence	females	0.0 %	1.0
SHIRPA	teeth presence	males	0.0 %	1.0
SHIRPA	teeth presence	both	0.0 %	1.0
SHIRPA	transfer arousal	females	1.0 %	1.0
SHIRPA	transfer arousal	males	2.0 %	1.0
SHIRPA	transfer arousal	both	1.0 %	1.0
SHIRPA	tremor	females	0.0 %	1.0
SHIRPA	tremor	males	0.0 %	1.0
SHIRPA	tremor	both	0.0 %	1.00
SHIRPA	trunk curl	females	0.0 %	1.00
SHIRPA	trunk curl	males	0.0 %	1.0
SHIRPA	trunk curl	both	0.0 %	1.00
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	females	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	males	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	both	0.0 %	1.0
SHIRPA	upper lip morphology	females	0.0 %	1.0
SHIRPA	upper lip morphology	males	0.0 %	1.0
SHIRPA	upper lip morphology	both	0.0 %	1.0
SHIRPA	upper teeth appearance	females	0.0 %	1.0
SHIRPA	upper teeth appearance	males	0.0 %	1.00
SHIRPA	upper teeth appearance	both	0.0 %	1.0
SHIRPA	vibrissae appearance	females	2.0 %	1.0
SHIRPA	vibrissae appearance	males	1.0 %	1.0
SHIRPA	vibrissae appearance	both	1.0 %	1.0
SHIRPA	vibrissae presence	females	2.0 %	1.00
SHIRPA	vibrissae presence	males	1.0 %	1.0
SHIRPA	vibrissae presence	both	2.0 %	1.0
SHIRPA	vocalization	females	2.0 %	1.00
SHIRPA	vocalization	males	2.0 %	1.0
SHIRPA	vocalization	both	2.0 %	1.0

GENOTYPE CORRELATION PLOT

Correlate Znfx1^em1(IMPC)J/Mmjax -/- with genotype:

This genotype correlation visualization can include both EAP and LAP measures.