MPD: JaxKOMP-EAP genotype: Fam168a<sup>em1(IMPC)J</sup>/Mmjax -/-

JaxKOMP-EAP effect sizes: Fam168a^em1(IMPC)J/Mmjax -/- Gene Fam168a

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

In this plot, data points are the computed genotype effect size vs. C57BL/6NJ controls, for all measured numeric phenotypes in JaxKOMP-EAP

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Significance Threshold p-Value Threshold Adjusted Unadjusted

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Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value

body composition	body length	0.16616	0.065243	1.8869	0.133	0.0192
body composition	body weight (at time of DXA)	-1.6307	0.79485	-1.0284	0.176	0.0529
body composition	bone area, whole body scan, head excluded	0.58024	0.24685	2.4264	0.158	0.0291
body composition	bone mineral content of whole body scan, head excluded	0.031248	0.017832	1.8977	0.313	0.0950
body composition	bone mineral content to body weight ratio	0.0010157	0.00074323	1.4738	0.440	0.187
body composition	bone mineral density of whole body scan, head excluded	0.00036000	0.00074190	0.41083	0.821	0.633
body composition	fat tissue mass of whole body scan, head excluded	-0.64608	0.47723	-1.2036	0.431	0.191
body composition	fat tissue mass to body weight ratio	-0.029131	0.016907	-1.2897	0.281	0.100
body composition	lean tissue mass of whole body scan, head excluded	0.99734	0.50187	1.6030	0.280	0.0608
body composition	lean tissue mass to body weight ratio	0.036316	0.012637	1.7284	0.0886	0.00939
body composition	percent fat, whole body scan, head excluded	-2.9231	1.4986	-1.3866	0.226	0.0653
body composition	ratio of soft-tissue attenuation coefficients	0.0032952	0.0016882	1.4108	0.228	0.0651
body composition	tissue area	-0.030707	0.35432	0.079355	0.983	0.932
body composition	total tissue mass, whole body scan, head excluded	0.44483	0.46758	0.71446	0.605	0.353
clinical blood chemistry	alanine transaminase (plasma ALT)	23.924	7.8969	1.3108	0.438	0.0939
clinical blood chemistry	albumin (plasma Alb)	-2.4935	0.85036	-2.5677	0.389	0.0993
clinical blood chemistry	alkaline phosphatase (plasma ALP)	-3.2405	4.2170	-1.0897	0.737	0.523
clinical blood chemistry	aspartate transaminase (plasma AST)	18.473	15.221	0.72152	0.667	0.349
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	-0.20047	0.17967	-0.64188	0.765	0.381
clinical blood chemistry	blood urea nitrogen (BUN)	-4.6952	1.4972	-1.6474	0.293	0.0884
clinical blood chemistry	calcium (plasma Ca)	-0.045091	0.15556	0.020618	0.894	0.799
clinical blood chemistry	creatinine (plasma)	-0.013228	0.017034	-0.22560	0.728	0.519
clinical blood chemistry	glucose (plasma GLU, no fast)	-17.341	18.105	-0.37802	0.642	0.439
clinical blood chemistry	HDL cholesterol (plasma HDL)	-5.6632	2.7862	-1.4382	0.465	0.179
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	0.041213	0.043601	1.8711	0.739	0.444
clinical blood chemistry	phosphorus (plasma phosphate)	3.4725	0.50861	2.7054	0.140	0.0208
clinical blood chemistry	total bilirubin (plasma TBIL)	-0.0011113	0.020139	-0.080993	0.989	0.961
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	-12.451	4.2521	-1.9416	0.349	0.0995
clinical blood chemistry	total protein (plasma TP)	-4.4250	1.2035	-2.2233	0.288	0.0667
clinical blood chemistry	triglyceride (plasma TG, no fast)	-55.801	11.822	-1.9389	0.213	0.0421
ERG v2.0	left eye a-wave amplitude (Photopic)	3.5872	2.0369	1.1829	0.626	0.220
ERG v2.0	left eye a-wave amplitude (Scotopic)	51.755	23.545	1.5792	0.543	0.159
ERG v2.0	left eye a-wave implicit timing (Photopic)	-0.93480	1.9828	-0.32226	0.965	0.684
ERG v2.0	left eye a-wave implicit timing (Scotopic)	1.9079	2.1999	1.5431	0.837	0.477
ERG v2.0	left eye b-wave amplitude (Photopic)	-1.5750	8.9072	-0.33604	0.944	0.876
ERG v2.0	left eye b-wave amplitude (Scotopic)	-137.82	53.695	-1.8098	0.517	0.124
ERG v2.0	left eye b-wave implicit timing (Photopic)	8.4060	13.403	1.6406	0.828	0.595
ERG v2.0	left eye b-wave implicit timing (Scotopic)	-10.139	6.2394	-0.98368	0.714	0.246
ERG v2.0	left eye c-wave amplitude (Scotopic)	-76.668	52.272	-1.3279	0.698	0.280
ERG v2.0	left eye c-wave implicit timing (Scotopic)	-99.001	102.21	-0.95868	0.779	0.435
ERG v2.0	left eye FO-like wave amplitude (Scotopic)	89.167	106.07	1.0593	0.775	0.489
ERG v2.0	left eye FO-like wave implicit timing (Scotopic)	-348.62	157.91	-1.0774	0.666	0.158
ERG v2.0	right eye a-wave amplitude (Photopic)	3.1142	1.9419	1.0593	0.731	0.250
ERG v2.0	right eye a-wave amplitude (Scotopic)	52.980	15.733	1.5998	0.473	0.0780
ERG v2.0	right eye a-wave implicit timing (Photopic)	2.5417	1.3051	1.2753	0.751	0.191
ERG v2.0	right eye a-wave implicit timing (Scotopic)	1.6830	1.7677	1.3389	0.804	0.442
ERG v2.0	right eye b-wave amplitude (Photopic)	-8.6308	7.8534	-0.89123	0.737	0.386
ERG v2.0	right eye b-wave amplitude (Scotopic)	-141.34	37.232	-1.8108	0.476	0.0629
ERG v2.0	right eye b-wave implicit timing (Photopic)	6.5277	12.389	1.6844	0.851	0.651
ERG v2.0	right eye b-wave implicit timing (Scotopic)	-7.7292	5.8508	-0.70941	0.792	0.317
ERG v2.0	right eye c-wave amplitude (Scotopic)	-80.875	37.676	-1.4272	0.562	0.165
ERG v2.0	right eye c-wave implicit timing (Scotopic)	-137.29	55.695	-1.3135	0.710	0.133
ERG v2.0	right eye FO-like wave amplitude (Scotopic)	127.68	48.792	1.6199	0.496	0.120
ERG v2.0	right eye FO-like wave implicit timing (Scotopic)	-146.37	404.44	-0.34769	0.938	0.752
glucose tolerance test	amount glucose injected	-3.4310	1.6171	-0.61815	0.297	0.0425
glucose tolerance test	plasma glucose, 0min	10.178	4.0044	0.80730	0.0792	0.0164
glucose tolerance test	plasma glucose, 15min	-10.631	20.683	-0.19338	0.855	0.611
glucose tolerance test	plasma glucose, 30min	-2.0132	15.502	0.079703	0.964	0.898
glucose tolerance test	plasma glucose, 60min	34.507	24.839	1.4091	0.489	0.175
glucose tolerance test	plasma glucose, 120min	8.2621	8.3134	0.41971	0.623	0.329
grip strength	body weight (at time of grip strength test)	-1.0532	0.47534	-0.74925	0.121	0.0379
grip strength	forelimb and hindlimb grip strength (mean of trials), average	-8.9977	9.4884	-0.40432	0.566	0.354
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	-0.058745	0.35234	0.12230	0.929	0.869
grip strength	forelimb and hindlimb grip strength by trial, trial1	4.0236	10.764	0.52907	0.881	0.712
grip strength	forelimb and hindlimb grip strength by trial, trial2	-2.7166	10.855	0.061033	0.898	0.805
grip strength	forelimb and hindlimb grip strength by trial, trial3	-20.591	12.119	-1.0690	0.328	0.104
grip strength	forelimb grip strength (mean of trials), average	-9.6083	3.9810	-0.88634	0.137	0.0250
grip strength	forelimb grip strength (mean of trials), average normalized to bw	-0.37339	0.21518	-0.71048	0.308	0.0981
grip strength	forelimb grip strength by trial, trial1	-11.838	5.9779	-1.0563	0.309	0.0609
grip strength	forelimb grip strength by trial, trial2	-7.9206	6.7236	-0.64292	0.575	0.252
grip strength	forelimb grip strength by trial, trial3	-14.363	8.1343	-1.2108	0.351	0.0920
heart weight	heart weight, normalized to body weight	0.26736	0.18299	0.47464	0.349	0.155
heart weight	heart weight, weight	-1.1400	4.7670	-0.52053	0.901	0.813
hematology	basophil differential (percent of total WBC)	0.24792	0.17766	2.2556	0.718	0.298
hematology	calculated hemoglobin (cHGB)	-0.42197	0.26845	-1.3024	0.539	0.257
hematology	eosinophil differential (percent of total WBC)	0.22292	0.19257	0.70968	0.749	0.367
hematology	hematocrit (HCT)	-0.13120	1.2287	-0.49669	0.964	0.925
hematology	hemoglobin concentration distribution width (HDW)	-0.024347	0.066950	-0.69537	0.891	0.751
hematology	large unstained cells (percent of total WBC)	0.14273	0.34436	0.90156	0.887	0.719
hematology	lymphocyte differential (percent of total WBC)	-0.70000	0.74471	-0.34572	0.674	0.446
hematology	mean corpuscular hemoglobin (CHr)	-0.015687	0.040418	-0.10736	0.874	0.735
hematology	mean platelet volume (MPV)	-0.42163	0.34993	-1.9124	0.582	0.351
hematology	mean RBC corpuscular hemoglobin (MCH)	-0.13333	0.20321	-0.51185	0.820	0.579
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	-0.69635	0.47474	-1.0686	0.644	0.280
hematology	mean RBC corpuscular volume (MCV)	0.65691	0.55540	1.1147	0.589	0.358
hematology	measured hemoglobin (mHGB)	-0.53392	0.30953	-1.2520	0.545	0.227
hematology	monocyte differential (percent of total WBC)	0.11667	0.12635	0.60981	0.751	0.453
hematology	neutrophil differential (percent of total WBC)	0.15000	0.61675	0.086212	0.914	0.831
hematology	platelet count (PLT; units per volume x 10³)	-29.463	114.32	-0.35444	0.940	0.821
hematology	RBC corpuscular distribution width (RDW)	0.24583	0.13443	0.85498	0.471	0.209
hematology	RBC corpuscular hemoglobin concentration mean (CHCM)	-0.57715	0.35131	-1.4445	0.500	0.242
hematology	red blood cell count (RBC; per volume x 10⁶)	-0.23278	0.20957	-1.2251	0.646	0.382
hematology	reticulocyte count (Retic; units per volume x 10⁹)	-39.722	18.511	-1.4352	0.552	0.165
hematology	reticulocyte differential (percent of total RBC)	-0.28862	0.15765	-0.99938	0.578	0.209
hematology	white blood cell count (WBC; units per volume x 10³)	-2.6251	2.4141	-1.4455	0.592	0.390
light / dark	latency to enter dark zone, 20 min test	-129.95	49.416	-2.3811	0.228	0.0130
light / dark	number of transitions between light and dark zones, 20 min test	-9.3882	5.4142	-0.84703	0.367	0.0925
light / dark	percentage of total time in dark zone, 20 min test	5.2619	3.2696	1.1038	0.467	0.117
light / dark	percentage of total time in light zone, 20 min test	-5.2619	3.2696	-1.1088	0.466	0.117
light / dark	time mobile in dark zone, 20 min test	45.459	10.703	1.8623	0.00520	0.000174
light / dark	time mobile in light zone, 20 min test	-9.7112	10.235	-0.92719	0.615	0.350
light / dark	time spent in dark zone, 20 min test	114.90	53.073	1.8623	0.319	0.0382
light / dark	time spent in light zone, 20 min test	-114.90	53.073	-1.8623	0.319	0.0382
open field	average speed in center of arena, 20 min test	0.87871	0.47080	1.3542	0.355	0.0760
open field	average speed in periphery of arena, 20 min test	0.49537	0.24026	1.2333	0.168	0.0518
open field	distance traveled habituation ratio, 20 min test	-18.907	9.3320	-1.5241	0.284	0.0557
open field	distance traveled in center of arena, 20 min test	434.30	149.52	1.8888	0.0664	0.00847
open field	distance traveled in periphery of arena, 20 min test	307.14	211.77	0.75020	0.373	0.162
open field	distance traveled slope, 20 min test	-15.572	8.5799	-1.3475	0.356	0.0838
open field	distance traveled, 20 min test, 1st 5min	243.25	89.699	1.4173	0.0788	0.0134
open field	distance traveled, 20 min test, 2nd 5min	173.61	96.416	1.2868	0.267	0.0869
open field	distance traveled, 20 min test, 3rd 5min	188.69	102.24	1.4706	0.253	0.0791
open field	distance traveled, 20 min test, 4th 5min	118.67	84.676	0.81401	0.394	0.176
open field	number of clockwise revolution episodes, 20 min test	4.1114	1.5543	1.5682	0.138	0.0155
open field	number of counter-clockwise revolution episodes, 20 min test	2.2699	1.8003	0.75020	0.508	0.221
open field	number of rears in 5 min bins, 20 min test, 1st 5min	-3.2301	2.8651	-1.0785	0.542	0.272
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	-4.4277	3.0895	-1.4173	0.448	0.167
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	-5.7072	3.1750	-1.5824	0.295	0.0866
open field	number of rears in 5 min bins, 20 min test, 4th 5min	-5.1482	3.7205	-1.4706	0.451	0.181
open field	percentage of total time in center of arena, 20 min test	5.6160	5.0251	1.0161	0.594	0.276
open field	percentage of total time in center of arena, slope, 20 min test	-2.5079	2.9594	-1.1724	0.818	0.407
open field	percentage of total time in center, habituation ratio, 20 min test	-1.4478	3.0204	-0.68082	0.897	0.637
open field	percentage of total time in corners of arena, 20 min test	-1.3165	6.2824	0.051713	0.939	0.836
open field	percentage of total time in corners, habituation ratio, 20 min test	6.5501	2.6111	2.2819	0.336	0.0204
open field	percentage of total time in corners, slope, 20 min test	6.1633	2.5715	2.2641	0.358	0.0259
open field	permanence time in center of arena, 20 min test	67.401	60.308	1.0161	0.595	0.276
open field	permanence time in corners of arena, 20 min test	-15.785	75.386	0.051713	0.939	0.836
open field	permanence time in periphery of arena, 20 min test	-67.410	60.293	-1.0161	0.594	0.276
open field	total distance traveled, 20 min test	741.44	323.91	1.4284	0.126	0.0325
open field	total number of rears, 20 min test	-18.513	11.277	-1.5459	0.323	0.116
open field	whole arena average speed, 20 min test	0.61870	0.26943	1.4321	0.125	0.0320
open field	whole arena resting time, 20 min test	-91.964	31.151	-1.6519	0.0443	0.00761
open field	whole arena time spent mobile, 20 min test	91.973	31.099	1.8006	0.0461	0.00752
open field	whole arena time spent vertical, 20 min test	-21.048	9.5658	-1.6262	0.232	0.0391
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	1.5245	1.9191	0.83158	0.708	0.436
startle / PPI	average baseline movement during background noise	3.8007	1.9226	1.8947	0.546	0.0607
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	-0.019016	0.15726	-0.26726	0.958	0.905
startle / PPI	average of each corrected percent pre-pulse inhibition value	-0.0025791	0.16940	-0.096233	0.996	0.988
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-1.8996	15.210	-0.15120	0.994	0.902
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	3.0122	14.608	0.24843	0.950	0.839
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-10.318	16.050	-1.0815	0.790	0.527
startle / PPI	average startle response to full pulse (120 dB)	-95.179	48.896	-1.3547	0.211	0.0645
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-89.919	57.495	-1.2781	0.334	0.132
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-97.602	49.048	-1.5022	0.198	0.0592
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-76.377	48.313	-1.3906	0.320	0.128
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	3.7515	2.3415	1.8020	0.661	0.123
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	2.4878	1.7038	1.2686	0.656	0.158
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	2.0453	1.6208	0.71778	0.666	0.221
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.028738	0.18937	-0.20244	0.982	0.881
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.015709	0.17696	0.069490	0.980	0.930
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.0052921	0.18088	-0.13499	0.990	0.977
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	-99.708	48.923	-1.4207	0.186	0.0537
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	-94.292	57.789	-1.3071	0.313	0.117
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	-100.14	49.173	-1.5333	0.184	0.0539
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	-78.363	48.433	-1.4093	0.300	0.120
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.053351	0.17445	-0.45132	0.955	0.763
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.012283	0.18325	-0.19326	0.978	0.947
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-0.098038	0.17475	-0.89601	0.784	0.581
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	-359.02	178.30	-1.4246	0.193	0.0564
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	-283.92	223.12	-1.1226	0.451	0.216
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	-337.22	179.16	-1.4363	0.222	0.0731
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	-288.93	175.30	-1.4207	0.290	0.114
startle / PPI	maximum baseline movement during background noise	9.1288	4.2135	1.8620	0.462	0.0414
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-5.0839	15.372	-0.47001	0.965	0.744
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.069973	16.160	-0.082058	0.999	0.997
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-9.4495	15.714	-0.95225	0.791	0.554
startle / PPI	maximum startle response to full pulse (120 dB)	-349.27	178.02	-1.4018	0.207	0.0625
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-274.78	222.45	-1.1148	0.473	0.230
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-332.50	179.28	-1.4093	0.229	0.0771
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-287.21	175.74	-1.4285	0.297	0.116
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	6.8975	6.3044	1.5852	0.746	0.286
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	3.8960	3.0875	0.94346	0.715	0.220
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	0.16143	3.3994	-0.12573	0.994	0.963

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

In this plot, data points are the computed genotype effect % vs. C57BL/6NJ controls, for all measured categorical phenotypes in JaxKOMP-EAP

Dimensions Width: × Height: px

Plot Options Group by Procedure

Include Sexes Data Both Females Males

Significance Threshold p-Value Threshold

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Procedure	JaxKOMP-EAP Trait	Sex	Trait Effect	P-value

eye morphology	anterior chamber depth	females	1.0 %	1.0
eye morphology	anterior chamber depth	males	0.0 %	1.0
eye morphology	anterior chamber depth	both	1.0 %	1.0
eye morphology	bulging eye	females	1.0 %	1.0
eye morphology	bulging eye	males	0.0 %	1.0
eye morphology	bulging eye	both	1.0 %	1.00
eye morphology	cornea	females	12.0 %	0.175
eye morphology	cornea	males	2.0 %	1.0
eye morphology	cornea	both	6.0 %	0.248
eye morphology	cornea opacity	females	5.0 %	1.00
eye morphology	cornea opacity	males	1.0 %	1.0
eye morphology	cornea opacity	both	3.0 %	1.00
eye morphology	cornea vascularization	females	3.0 %	1.0
eye morphology	cornea vascularization	males	1.0 %	1.0
eye morphology	cornea vascularization	both	2.0 %	1.00
eye morphology	corneal deposits	females	2.0 %	1.0
eye morphology	corneal deposits	males	1.0 %	1.0
eye morphology	corneal deposits	both	1.0 %	1.00
eye morphology	corneal mineralization	females	2.0 %	1.0
eye morphology	corneal mineralization	males	1.0 %	1.0
eye morphology	corneal mineralization	both	1.0 %	1.00
eye morphology	corneal scleralization	females	3.0 %	1.00
eye morphology	corneal scleralization	males	1.0 %	1.0
eye morphology	corneal scleralization	both	2.0 %	1.00
eye morphology	corneal ulcer	females	1.0 %	1.0
eye morphology	corneal ulcer	males	1.0 %	1.0
eye morphology	corneal ulcer	both	1.0 %	1.00
eye morphology	eye closure	females	1.0 %	1.00
eye morphology	eye closure	males	0.0 %	1.0
eye morphology	eye closure	both	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	females	2.0 %	1.00
eye morphology	eye hemorrhage or blood presence	males	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	both	1.0 %	1.00
eye morphology	eyelid morphology	females	1.0 %	1.0
eye morphology	eyelid morphology	males	0.0 %	1.0
eye morphology	eyelid morphology	both	1.0 %	1.0
eye morphology	eyes (present, absent)	females	1.0 %	1.0
eye morphology	eyes (present, absent)	males	0.0 %	1.0
eye morphology	eyes (present, absent)	both	0.0 %	1.0
eye morphology	fusion between cornea and lens	females	4.0 %	1.00
eye morphology	fusion between cornea and lens	males	2.0 %	1.0
eye morphology	fusion between cornea and lens	both	3.0 %	1.00
eye morphology	iris pigmentation	females	2.0 %	1.0
eye morphology	iris pigmentation	males	1.0 %	1.0
eye morphology	iris pigmentation	both	2.0 %	1.00
eye morphology	iris transillumination	females	2.0 %	1.00
eye morphology	iris transillumination	males	1.0 %	1.0
eye morphology	iris transillumination	both	1.0 %	1.00
eye morphology	irispupil	females	4.0 %	1.00
eye morphology	irispupil	males	12.0 %	0.127
eye morphology	irispupil	both	5.0 %	0.301
eye morphology	lacrimation	females	3.0 %	1.0
eye morphology	lacrimation	males	2.0 %	1.0
eye morphology	lacrimation	both	3.0 %	1.0
eye morphology	lens	females	10.0 %	1.00
eye morphology	lens	males	8.0 %	1.0
eye morphology	lens	both	9.0 %	1.0
eye morphology	lens opacity	females	9.0 %	1.0
eye morphology	lens opacity	males	6.0 %	1.0
eye morphology	lens opacity	both	7.0 %	1.00
eye morphology	narrow eye opening	females	2.0 %	1.0
eye morphology	narrow eye opening	males	1.0 %	1.0
eye morphology	narrow eye opening	both	1.0 %	1.0
eye morphology	optic disc	females	4.0 %	1.00
eye morphology	optic disc	males	2.0 %	1.0
eye morphology	optic disc	both	3.0 %	1.00
eye morphology	persistence of hyaloid vascular system	females	14.0 %	1.0
eye morphology	persistence of hyaloid vascular system	males	5.0 %	1.0
eye morphology	persistence of hyaloid vascular system	both	9.0 %	1.00
eye morphology	pupil dilation	females	2.0 %	1.0
eye morphology	pupil dilation	males	1.0 %	1.0
eye morphology	pupil dilation	both	2.0 %	1.0
eye morphology	pupil light response	females	2.0 %	1.00
eye morphology	pupil light response	males	1.0 %	1.0
eye morphology	pupil light response	both	2.0 %	1.00
eye morphology	pupil position	females	4.0 %	1.00
eye morphology	pupil position	males	12.0 %	0.128
eye morphology	pupil position	both	5.0 %	0.321
eye morphology	pupil shape	females	3.0 %	1.00
eye morphology	pupil shape	males	2.0 %	1.0
eye morphology	pupil shape	both	3.0 %	1.00
eye morphology	retina	females	10.0 %	1.0
eye morphology	retina	males	16.0 %	1.0
eye morphology	retina	both	13.0 %	1.0
eye morphology	retinal blood vessels	females	4.0 %	1.0
eye morphology	retinal blood vessels	males	2.0 %	1.0
eye morphology	retinal blood vessels	both	3.0 %	1.0
eye morphology	retinal blood vessels pattern	females	5.0 %	1.0
eye morphology	retinal blood vessels pattern	males	2.0 %	1.0
eye morphology	retinal blood vessels pattern	both	4.0 %	1.00
eye morphology	retinal blood vessels structure	females	4.0 %	1.00
eye morphology	retinal blood vessels structure	males	2.0 %	1.0
eye morphology	retinal blood vessels structure	both	3.0 %	1.00
eye morphology	retinal pigmentation	females	96.0 %	2.79e-9
eye morphology	retinal pigmentation	males	70.0 %	0.0000478
eye morphology	retinal pigmentation	both	83.0 %	1.65e-13
eye morphology	retinal structure	females	4.0 %	1.00
eye morphology	retinal structure	males	2.0 %	1.0
eye morphology	retinal structure	both	3.0 %	1.00
eye morphology	synechia	females	4.0 %	1.0
eye morphology	synechia	males	2.0 %	1.0
eye morphology	synechia	both	3.0 %	1.00
eye morphology	vitreous	females	4.0 %	1.00
eye morphology	vitreous	males	2.0 %	1.0
eye morphology	vitreous	both	3.0 %	1.00
SHIRPA	activity body position	females	12.0 %	0.0797
SHIRPA	activity body position	males	2.0 %	1.0
SHIRPA	activity body position	both	6.0 %	0.193
SHIRPA	aggression	females	0.0 %	1.00
SHIRPA	aggression	males	1.0 %	1.0
SHIRPA	aggression	both	1.0 %	1.0
SHIRPA	body length	females	0.0 %	1.0
SHIRPA	body length	males	0.0 %	1.00
SHIRPA	body length	both	0.0 %	1.00
SHIRPA	body position	females	0.0 %	1.0
SHIRPA	body position	males	1.0 %	1.0
SHIRPA	body position	both	0.0 %	1.0
SHIRPA	body thickness	females	1.0 %	1.0
SHIRPA	body thickness	males	0.0 %	1.0
SHIRPA	body thickness	both	0.0 %	1.0
SHIRPA	coat color abdomen	females	3.0 %	1.00
SHIRPA	coat color abdomen	males	4.0 %	1.0
SHIRPA	coat color abdomen	both	4.0 %	1.0
SHIRPA	coat color back	females	0.0 %	1.0
SHIRPA	coat color back	males	0.0 %	1.00
SHIRPA	coat color back	both	0.0 %	1.00
SHIRPA	coat color head	females	0.0 %	1.0
SHIRPA	coat color head	males	0.0 %	1.00
SHIRPA	coat color head	both	0.0 %	1.0
SHIRPA	coat color pattern abdomen	females	1.0 %	1.0
SHIRPA	coat color pattern abdomen	males	1.0 %	1.0
SHIRPA	coat color pattern abdomen	both	1.0 %	1.0
SHIRPA	coat color pattern back	females	0.0 %	1.0
SHIRPA	coat color pattern back	males	0.0 %	1.00
SHIRPA	coat color pattern back	both	0.0 %	1.0
SHIRPA	coat color pattern head	females	0.0 %	1.0
SHIRPA	coat color pattern head	males	0.0 %	1.0
SHIRPA	coat color pattern head	both	0.0 %	1.00
SHIRPA	coat hair abdomen texture appearance	females	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	males	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	both	2.0 %	1.0
SHIRPA	coat hair back texture appearance	females	0.0 %	1.0
SHIRPA	coat hair back texture appearance	males	0.0 %	1.0
SHIRPA	coat hair back texture appearance	both	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	females	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	males	1.0 %	1.00
SHIRPA	coat hair distribution abdomen	both	1.0 %	1.00
SHIRPA	coat hair distribution back	females	0.0 %	1.0
SHIRPA	coat hair distribution back	males	0.0 %	1.0
SHIRPA	coat hair distribution back	both	0.0 %	1.0
SHIRPA	coat hair distribution head	females	1.0 %	1.00
SHIRPA	coat hair distribution head	males	1.0 %	1.0
SHIRPA	coat hair distribution head	both	1.0 %	1.0
SHIRPA	coat hair head texture appearance	females	0.0 %	1.00
SHIRPA	coat hair head texture appearance	males	0.0 %	1.0
SHIRPA	coat hair head texture appearance	both	0.0 %	1.0
SHIRPA	contact righting	females	5.0 %	1.0
SHIRPA	contact righting	males	5.0 %	1.00
SHIRPA	contact righting	both	5.0 %	1.00
SHIRPA	ear morphology	females	0.0 %	1.0
SHIRPA	ear morphology	males	0.0 %	1.0
SHIRPA	ear morphology	both	0.0 %	1.0
SHIRPA	fat distribution	females	0.0 %	1.0
SHIRPA	fat distribution	males	0.0 %	1.0
SHIRPA	fat distribution	both	0.0 %	1.00
SHIRPA	forelimb digit number	females	0.0 %	1.00
SHIRPA	forelimb digit number	males	0.0 %	1.0
SHIRPA	forelimb digit number	both	0.0 %	1.00
SHIRPA	forelimb digit position	females	0.0 %	1.0
SHIRPA	forelimb digit position	males	0.0 %	1.0
SHIRPA	forelimb digit position	both	0.0 %	1.0
SHIRPA	forelimb digit shape	females	0.0 %	1.0
SHIRPA	forelimb digit shape	males	0.0 %	1.0
SHIRPA	forelimb digit shape	both	0.0 %	1.0
SHIRPA	forelimb digit size	females	0.0 %	1.0
SHIRPA	forelimb digit size	males	0.0 %	1.0
SHIRPA	forelimb digit size	both	0.0 %	1.0
SHIRPA	forelimb footpads	females	0.0 %	1.0
SHIRPA	forelimb footpads	males	0.0 %	1.0
SHIRPA	forelimb footpads	both	0.0 %	1.0
SHIRPA	forelimb nail length	females	0.0 %	1.0
SHIRPA	forelimb nail length	males	0.0 %	1.0
SHIRPA	forelimb nail length	both	0.0 %	1.0
SHIRPA	forelimb nail number	females	0.0 %	1.0
SHIRPA	forelimb nail number	males	0.0 %	1.0
SHIRPA	forelimb nail number	both	0.0 %	1.0
SHIRPA	forelimb nail position	females	0.0 %	1.0
SHIRPA	forelimb nail position	males	0.0 %	1.0
SHIRPA	forelimb nail position	both	0.0 %	1.0
SHIRPA	forelimb nail shape	females	0.0 %	1.0
SHIRPA	forelimb nail shape	males	0.0 %	1.0
SHIRPA	forelimb nail shape	both	0.0 %	1.0
SHIRPA	forelimbs position	females	0.0 %	1.0
SHIRPA	forelimbs position	males	0.0 %	1.0
SHIRPA	forelimbs position	both	0.0 %	1.0
SHIRPA	forelimbs shape	females	0.0 %	1.0
SHIRPA	forelimbs shape	males	0.0 %	1.0
SHIRPA	forelimbs shape	both	0.0 %	1.0
SHIRPA	forelimbs size	females	0.0 %	1.0
SHIRPA	forelimbs size	males	0.0 %	1.0
SHIRPA	forelimbs size	both	0.0 %	1.0
SHIRPA	forepaw position	females	0.0 %	1.0
SHIRPA	forepaw position	males	0.0 %	1.0
SHIRPA	forepaw position	both	0.0 %	1.0
SHIRPA	forepaw shape	females	0.0 %	1.0
SHIRPA	forepaw shape	males	0.0 %	1.0
SHIRPA	forepaw shape	both	0.0 %	1.0
SHIRPA	forepaw size	females	0.0 %	1.0
SHIRPA	forepaw size	males	0.0 %	1.0
SHIRPA	forepaw size	both	0.0 %	1.0
SHIRPA	gait (fluidity)	females	0.0 %	1.0
SHIRPA	gait (fluidity)	males	0.0 %	1.00
SHIRPA	gait (fluidity)	both	0.0 %	1.00
SHIRPA	genitalia morphology	females	0.0 %	1.00
SHIRPA	genitalia morphology	males	0.0 %	1.0
SHIRPA	genitalia morphology	both	0.0 %	1.00
SHIRPA	genitalia presence	females	0.0 %	1.0
SHIRPA	genitalia presence	males	0.0 %	1.0
SHIRPA	genitalia presence	both	0.0 %	1.0
SHIRPA	genitalia size	females	0.0 %	1.0
SHIRPA	genitalia size	males	0.0 %	1.0
SHIRPA	genitalia size	both	0.0 %	1.0
SHIRPA	head bobbing	females	0.0 %	1.0
SHIRPA	head bobbing	males	0.0 %	1.0
SHIRPA	head bobbing	both	0.0 %	1.0
SHIRPA	head morphology	females	0.0 %	1.0
SHIRPA	head morphology	males	0.0 %	1.00
SHIRPA	head morphology	both	0.0 %	1.0
SHIRPA	head size	females	0.0 %	1.0
SHIRPA	head size	males	0.0 %	1.0
SHIRPA	head size	both	0.0 %	1.00
SHIRPA	hindlimb digit number	females	1.0 %	1.00
SHIRPA	hindlimb digit number	males	0.0 %	1.0
SHIRPA	hindlimb digit number	both	0.0 %	1.00
SHIRPA	hindlimb digit position	females	0.0 %	1.0
SHIRPA	hindlimb digit position	males	0.0 %	1.0
SHIRPA	hindlimb digit position	both	0.0 %	1.0
SHIRPA	hindlimb digit shape	females	0.0 %	1.0
SHIRPA	hindlimb digit shape	males	0.0 %	1.0
SHIRPA	hindlimb digit shape	both	0.0 %	1.0
SHIRPA	hindlimb digit size	females	0.0 %	1.00
SHIRPA	hindlimb digit size	males	0.0 %	1.0
SHIRPA	hindlimb digit size	both	0.0 %	1.00
SHIRPA	hindlimb nail length	females	0.0 %	1.0
SHIRPA	hindlimb nail length	males	0.0 %	1.0
SHIRPA	hindlimb nail length	both	0.0 %	1.00
SHIRPA	hindlimb nail number	females	0.0 %	1.0
SHIRPA	hindlimb nail number	males	1.0 %	1.0
SHIRPA	hindlimb nail number	both	0.0 %	1.00
SHIRPA	hindlimb nail position	females	0.0 %	1.0
SHIRPA	hindlimb nail position	males	0.0 %	1.0
SHIRPA	hindlimb nail position	both	0.0 %	1.0
SHIRPA	hindlimb nail shape	females	0.0 %	1.0
SHIRPA	hindlimb nail shape	males	0.0 %	1.0
SHIRPA	hindlimb nail shape	both	0.0 %	1.0
SHIRPA	hindlimbs footpads	females	0.0 %	1.0
SHIRPA	hindlimbs footpads	males	0.0 %	1.0
SHIRPA	hindlimbs footpads	both	0.0 %	1.0
SHIRPA	hindlimbs position	females	0.0 %	1.0
SHIRPA	hindlimbs position	males	0.0 %	1.0
SHIRPA	hindlimbs position	both	0.0 %	1.0
SHIRPA	hindlimbs shape	females	0.0 %	1.0
SHIRPA	hindlimbs shape	males	0.0 %	1.0
SHIRPA	hindlimbs shape	both	0.0 %	1.0
SHIRPA	hindlimbs size	females	0.0 %	1.0
SHIRPA	hindlimbs size	males	0.0 %	1.0
SHIRPA	hindlimbs size	both	0.0 %	1.0
SHIRPA	hindpaw position	females	0.0 %	1.0
SHIRPA	hindpaw position	males	0.0 %	1.0
SHIRPA	hindpaw position	both	0.0 %	1.0
SHIRPA	hindpaw shape	females	0.0 %	1.0
SHIRPA	hindpaw shape	males	0.0 %	1.0
SHIRPA	hindpaw shape	both	0.0 %	1.0
SHIRPA	hindpaw size	females	0.0 %	1.0
SHIRPA	hindpaw size	males	0.0 %	1.0
SHIRPA	hindpaw size	both	0.0 %	1.0
SHIRPA	limb grasp	females	16.0 %	0.154
SHIRPA	limb grasp	males	7.0 %	0.375
SHIRPA	limb grasp	both	11.0 %	0.106
SHIRPA	lower lip morphology	females	0.0 %	1.0
SHIRPA	lower lip morphology	males	0.0 %	1.0
SHIRPA	lower lip morphology	both	0.0 %	1.0
SHIRPA	lower teeth appearance	females	0.0 %	1.0
SHIRPA	lower teeth appearance	males	0.0 %	1.00
SHIRPA	lower teeth appearance	both	0.0 %	1.00
SHIRPA	mouth morphology	females	0.0 %	1.0
SHIRPA	mouth morphology	males	0.0 %	1.00
SHIRPA	mouth morphology	both	0.0 %	1.00
SHIRPA	salivation	females	0.0 %	1.0
SHIRPA	salivation	males	0.0 %	1.0
SHIRPA	salivation	both	0.0 %	1.0
SHIRPA	skin color back paws	females	0.0 %	1.0
SHIRPA	skin color back paws	males	0.0 %	1.0
SHIRPA	skin color back paws	both	0.0 %	1.0
SHIRPA	skin color ear	females	0.0 %	1.0
SHIRPA	skin color ear	males	0.0 %	1.0
SHIRPA	skin color ear	both	0.0 %	1.0
SHIRPA	skin color front paws	females	0.0 %	1.0
SHIRPA	skin color front paws	males	0.0 %	1.0
SHIRPA	skin color front paws	both	0.0 %	1.0
SHIRPA	skin color snout	females	0.0 %	1.0
SHIRPA	skin color snout	males	0.0 %	1.0
SHIRPA	skin color snout	both	0.0 %	1.0
SHIRPA	skin color tail	females	0.0 %	1.0
SHIRPA	skin color tail	males	0.0 %	1.0
SHIRPA	skin color tail	both	0.0 %	1.0
SHIRPA	skin color whole body	females	0.0 %	1.0
SHIRPA	skin color whole body	males	0.0 %	1.0
SHIRPA	skin color whole body	both	0.0 %	1.0
SHIRPA	skin texture back paw	females	0.0 %	1.0
SHIRPA	skin texture back paw	males	0.0 %	1.0
SHIRPA	skin texture back paw	both	0.0 %	1.0
SHIRPA	skin texture ear	females	0.0 %	1.0
SHIRPA	skin texture ear	males	0.0 %	1.0
SHIRPA	skin texture ear	both	0.0 %	1.0
SHIRPA	skin texture front paws	females	0.0 %	1.0
SHIRPA	skin texture front paws	males	0.0 %	1.0
SHIRPA	skin texture front paws	both	0.0 %	1.0
SHIRPA	skin texture snout	females	0.0 %	1.0
SHIRPA	skin texture snout	males	0.0 %	1.0
SHIRPA	skin texture snout	both	0.0 %	1.0
SHIRPA	skin texture tail	females	0.0 %	1.0
SHIRPA	skin texture tail	males	0.0 %	1.0
SHIRPA	skin texture tail	both	0.0 %	1.0
SHIRPA	skin texture whole body	females	0.0 %	1.0
SHIRPA	skin texture whole body	males	0.0 %	1.00
SHIRPA	skin texture whole body	both	0.0 %	1.00
SHIRPA	snout size	females	0.0 %	1.0
SHIRPA	snout size	males	1.0 %	1.0
SHIRPA	snout size	both	0.0 %	1.0
SHIRPA	startle response	females	0.0 %	1.00
SHIRPA	startle response	males	0.0 %	1.00
SHIRPA	startle response	both	0.0 %	1.00
SHIRPA	tail curvature	females	0.0 %	1.00
SHIRPA	tail curvature	males	0.0 %	1.0
SHIRPA	tail curvature	both	0.0 %	1.0
SHIRPA	tail elevation	females	1.0 %	1.00
SHIRPA	tail elevation	males	2.0 %	1.0
SHIRPA	tail elevation	both	1.0 %	1.0
SHIRPA	tail length	females	0.0 %	1.0
SHIRPA	tail length	males	0.0 %	1.0
SHIRPA	tail length	both	0.0 %	1.00
SHIRPA	tail morphology	females	0.0 %	1.00
SHIRPA	tail morphology	males	0.0 %	1.0
SHIRPA	tail morphology	both	0.0 %	1.00
SHIRPA	tail presence	females	0.0 %	1.0
SHIRPA	tail presence	males	0.0 %	1.0
SHIRPA	tail presence	both	0.0 %	1.0
SHIRPA	tail shape	females	0.0 %	1.0
SHIRPA	tail shape	males	0.0 %	1.0
SHIRPA	tail shape	both	0.0 %	1.00
SHIRPA	tail thickness	females	0.0 %	1.0
SHIRPA	tail thickness	males	0.0 %	1.0
SHIRPA	tail thickness	both	0.0 %	1.0
SHIRPA	teeth presence	females	0.0 %	1.0
SHIRPA	teeth presence	males	0.0 %	1.00
SHIRPA	teeth presence	both	0.0 %	1.00
SHIRPA	transfer arousal	females	12.0 %	0.0876
SHIRPA	transfer arousal	males	2.0 %	1.00
SHIRPA	transfer arousal	both	6.0 %	0.202
SHIRPA	tremor	females	0.0 %	1.0
SHIRPA	tremor	males	0.0 %	1.0
SHIRPA	tremor	both	0.0 %	1.00
SHIRPA	trunk curl	females	0.0 %	1.00
SHIRPA	trunk curl	males	0.0 %	1.0
SHIRPA	trunk curl	both	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	females	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	males	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	both	0.0 %	1.00
SHIRPA	upper lip morphology	females	0.0 %	1.0
SHIRPA	upper lip morphology	males	0.0 %	1.0
SHIRPA	upper lip morphology	both	0.0 %	1.0
SHIRPA	upper teeth appearance	females	0.0 %	1.0
SHIRPA	upper teeth appearance	males	0.0 %	1.0
SHIRPA	upper teeth appearance	both	0.0 %	1.00
SHIRPA	vibrissae appearance	females	2.0 %	1.0
SHIRPA	vibrissae appearance	males	1.0 %	1.0
SHIRPA	vibrissae appearance	both	1.0 %	1.0
SHIRPA	vibrissae presence	females	2.0 %	1.00
SHIRPA	vibrissae presence	males	1.0 %	1.0
SHIRPA	vibrissae presence	both	2.0 %	1.0
SHIRPA	vocalization	males	2.0 %	1.0
SHIRPA	vocalization	both	2.0 %	1.0

GENOTYPE CORRELATION PLOT

Correlate Fam168a^em1(IMPC)J/Mmjax -/- with genotype:

This genotype correlation visualization can include both EAP and LAP measures.