MPD: JaxKOMP-EAP genotype: Rufy1<sup>em1(IMPC)J</sup>/Mmjax -/-

JaxKOMP-EAP effect sizes: Rufy1^em1(IMPC)J/Mmjax -/- Gene Rufy1

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

In this plot, data points are the computed genotype effect size vs. C57BL/6NJ controls, for all measured numeric phenotypes in JaxKOMP-EAP

Dimensions Width: × Height: px

Plot Options Group by Procedure Standard Error Show Effect Sizes RankZ

Significance Threshold p-Value Threshold Adjusted Unadjusted

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Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value

ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	5.5193	5.9833	1.2186	0.798	0.408
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	0.99418	7.8725	0.21780	0.970	0.906
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	4.6094	4.0387	0.73689	0.678	0.317
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	4.2188	3.9585	0.56571	0.708	0.347
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	4.5312	3.8499	0.68332	0.667	0.304
body composition	body length	-0.081505	0.050972	-0.73120	0.375	0.120
body composition	body weight (at time of DXA)	0.81237	0.72902	0.76146	0.492	0.273
body composition	bone area, whole body scan, head excluded	-0.23917	0.13043	-0.77021	0.278	0.0760
body composition	bone mineral content of whole body scan, head excluded	-0.012784	0.010815	-0.56686	0.535	0.246
body composition	bone mineral content to body weight ratio	-0.00018179	0.00053924	-0.064212	0.874	0.738
body composition	bone mineral density of whole body scan, head excluded	-0.000040000	0.00060662	-0.019808	0.985	0.948
body composition	fat tissue mass of whole body scan, head excluded	0.33208	0.53968	0.54456	0.759	0.543
body composition	fat tissue mass to body weight ratio	0.0094186	0.016340	0.48993	0.769	0.568
body composition	lean tissue mass of whole body scan, head excluded	-0.75118	0.48396	-1.5028	0.417	0.131
body composition	lean tissue mass to body weight ratio	-0.014490	0.013064	-0.83386	0.533	0.276
body composition	percent fat, whole body scan, head excluded	0.98233	1.5439	0.54298	0.739	0.529
body composition	ratio of soft-tissue attenuation coefficients	-0.0010892	0.0017159	-0.54746	0.737	0.530
body composition	tissue area	-0.046818	0.35197	0.025971	0.967	0.895
body composition	total tissue mass, whole body scan, head excluded	-0.41501	0.64355	-1.2469	0.731	0.524
clinical blood chemistry	alanine transaminase (plasma ALT)	5.3958	7.5550	0.41935	0.836	0.549
clinical blood chemistry	albumin (plasma Alb)	-0.16204	0.47966	-0.18498	0.919	0.768
clinical blood chemistry	alkaline phosphatase (plasma ALP)	5.1764	6.1476	0.43955	0.711	0.488
clinical blood chemistry	aspartate transaminase (plasma AST)	6.9310	12.423	0.33659	0.858	0.633
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	-0.050550	0.44355	-0.14959	0.980	0.920
clinical blood chemistry	blood urea nitrogen (BUN)	3.4120	1.7276	1.3044	0.438	0.187
clinical blood chemistry	calcium (plasma Ca)	-0.047660	0.14228	0.0035545	0.876	0.770
clinical blood chemistry	creatinine (plasma)	0.017894	0.024205	0.55298	0.744	0.537
clinical blood chemistry	glucose (plasma GLU, no fast)	33.917	13.264	1.5907	0.299	0.125
clinical blood chemistry	HDL cholesterol (plasma HDL)	-0.59772	3.1292	-0.47733	0.956	0.866
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	-0.0026005	0.024942	-0.30724	0.981	0.926
clinical blood chemistry	phosphorus (plasma phosphate)	-0.20152	0.99523	-0.38939	0.942	0.858
clinical blood chemistry	total bilirubin (plasma TBIL)	-0.0036913	0.014789	-0.28780	0.940	0.826
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	0.90904	4.7860	-0.077566	0.951	0.867
clinical blood chemistry	total protein (plasma TP)	0.70999	0.87250	0.47715	0.728	0.501
clinical blood chemistry	triglyceride (plasma TG, no fast)	33.741	13.629	1.6709	0.400	0.132
glucose tolerance test	amount glucose injected	-3.5936	12.286	-0.67578	0.942	0.819
glucose tolerance test	plasma glucose, 0min	3.3606	4.6462	0.12110	0.782	0.601
glucose tolerance test	plasma glucose, 15min	66.160	26.883	1.7638	0.577	0.246
glucose tolerance test	plasma glucose, 30min	45.662	17.714	1.4355	0.575	0.236
glucose tolerance test	plasma glucose, 60min	0.72500	16.840	0.15714	0.987	0.973
glucose tolerance test	plasma glucose, 120min	-15.219	8.2825	-1.1808	0.617	0.317
grip strength	body weight (at time of grip strength test)	0.026875	0.45294	0.23720	0.973	0.953
grip strength	forelimb and hindlimb grip strength (mean of trials), average	-20.294	5.0134	-1.1220	0.00530	0.000320
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	-0.81025	0.18194	-0.96202	0.00320	0.0000965
grip strength	forelimb and hindlimb grip strength by trial, trial1	-21.562	6.5820	-1.1753	0.0374	0.00254
grip strength	forelimb and hindlimb grip strength by trial, trial2	-18.664	5.7208	-0.92798	0.0379	0.00269
grip strength	forelimb and hindlimb grip strength by trial, trial3	-19.739	7.9058	-1.0214	0.117	0.0181
grip strength	forelimb grip strength (mean of trials), average	-5.7458	3.2658	-0.46013	0.288	0.0881
grip strength	forelimb grip strength (mean of trials), average normalized to bw	-0.22418	0.14928	-0.34049	0.392	0.143
grip strength	forelimb grip strength by trial, trial1	-7.3750	4.6122	-0.60063	0.406	0.120
grip strength	forelimb grip strength by trial, trial2	-4.0250	5.1880	-0.23599	0.752	0.444
grip strength	forelimb grip strength by trial, trial3	-5.8375	4.8360	-0.39959	0.558	0.236
heart weight	heart weight, normalized to body weight	-0.78334	0.22028	-2.6266	0.0207	0.00198
heart weight	heart weight, weight	1.4142	4.4710	-0.18551	0.864	0.755
hematology	basophil differential (percent of total WBC)	-0.011343	0.038877	-0.15714	0.948	0.798
hematology	eosinophil differential (percent of total WBC)	-0.24668	0.40325	-0.60772	0.872	0.603
hematology	hematocrit (HCT)	1.0970	0.70210	0.91147	0.561	0.259
hematology	lymphocyte differential (percent of total WBC)	1.5994	2.3064	0.55954	0.756	0.560
hematology	mean corpuscular hemoglobin (CHr)	0.034007	0.066673	0.30829	0.833	0.661
hematology	mean platelet volume (MPV)	-0.21771	0.19058	-1.3027	0.598	0.372
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	0.50000	0.59798	0.98063	0.795	0.491
hematology	mean RBC corpuscular volume (MCV)	-0.36945	0.52945	-0.67879	0.755	0.558
hematology	measured hemoglobin (mHGB)	0.73359	0.44152	1.5924	0.556	0.239
hematology	monocyte differential (percent of total WBC)	0.0036237	1.5871	0.22326	0.998	0.998
hematology	neutrophil differential (percent of total WBC)	-1.6333	1.1911	-0.72601	0.548	0.304
hematology	platelet count (PLT; units per volume x 10³)	-5.9458	44.328	-0.030073	0.970	0.906
hematology	RBC corpuscular distribution width (RDW)	-0.18643	4.2198	-0.68702	0.986	0.969
hematology	red blood cell count (RBC; per volume x 10⁶)	0.39699	0.24455	1.3677	0.516	0.246
hematology	reticulocyte count (Retic; units per volume x 10⁹)	-63.295	18.443	-2.2058	0.412	0.0754
hematology	reticulocyte differential (percent of total RBC)	-0.74650	0.21785	-2.2787	0.396	0.0756
hematology	white blood cell count (WBC; units per volume x 10³)	-1.2356	1.2329	-0.67707	0.614	0.422
open field	average speed in center of arena, 20 min test	-0.52274	0.62572	-1.0836	0.736	0.412
open field	average speed in periphery of arena, 20 min test	0.33158	0.29791	0.74134	0.503	0.278
open field	distance traveled habituation ratio, 20 min test	15.153	11.718	1.2391	0.529	0.209
open field	distance traveled in center of arena, 20 min test	426.65	170.01	1.8654	0.116	0.0204
open field	distance traveled in periphery of arena, 20 min test	-54.358	282.75	-0.65066	0.933	0.849
open field	distance traveled slope, 20 min test	10.453	10.335	0.92781	0.645	0.323
open field	distance traveled, 20 min test, 1st 5min	-44.406	135.73	-0.71508	0.885	0.747
open field	distance traveled, 20 min test, 2nd 5min	199.18	117.19	1.4785	0.293	0.103
open field	distance traveled, 20 min test, 3rd 5min	97.626	110.70	0.62761	0.639	0.387
open field	distance traveled, 20 min test, 4th 5min	114.23	93.388	0.75376	0.472	0.234
open field	number of clockwise revolution episodes, 20 min test	3.6680	1.7496	1.4318	0.276	0.0483
open field	number of counter-clockwise revolution episodes, 20 min test	2.6813	2.3311	0.97639	0.549	0.262
open field	number of rears in 5 min bins, 20 min test, 1st 5min	3.4427	3.3766	0.75336	0.583	0.319
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	7.1524	3.7863	1.4064	0.286	0.0721
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	3.6837	4.7000	0.56347	0.701	0.442
open field	number of rears in 5 min bins, 20 min test, 4th 5min	5.2149	4.7433	0.80284	0.559	0.283
open field	percentage of total time in center of arena, 20 min test	17.422	6.2457	2.7848	0.139	0.0107
open field	percentage of total time in center of arena, slope, 20 min test	2.2283	1.2710	1.3575	0.541	0.0942
open field	percentage of total time in center, habituation ratio, 20 min test	2.3364	1.3416	1.3850	0.539	0.0956
open field	percentage of total time in corners of arena, 20 min test	-10.630	6.0812	-1.6162	0.375	0.0944
open field	percentage of total time in corners, habituation ratio, 20 min test	0.14337	2.4257	-0.22131	0.995	0.953
open field	percentage of total time in corners, slope, 20 min test	0.67075	2.3813	0.044992	0.950	0.781
open field	permanence time in center of arena, 20 min test	209.08	74.953	2.7848	0.139	0.0107
open field	permanence time in corners of arena, 20 min test	-127.55	72.973	-1.6162	0.375	0.0944
open field	permanence time in periphery of arena, 20 min test	-209.13	74.957	-2.7848	0.139	0.0107
open field	total distance traveled, 20 min test	344.15	405.90	0.49702	0.621	0.406
open field	total number of rears, 20 min test	18.042	15.045	0.88727	0.489	0.243
open field	whole arena average speed, 20 min test	0.28615	0.33831	0.49702	0.623	0.407
open field	whole arena resting time, 20 min test	-20.944	35.894	-0.061126	0.733	0.565
open field	whole arena time spent mobile, 20 min test	17.006	29.086	0.18977	0.735	0.565
open field	whole arena time spent vertical, 20 min test	3.5612	9.5069	0.16930	0.889	0.712
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	0.83750	1.0016	0.53849	0.689	0.409
startle / PPI	average baseline movement during background noise	1.2542	1.6354	0.81947	0.874	0.449
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	0.018049	0.081480	0.053970	0.933	0.826
startle / PPI	average of each corrected percent pre-pulse inhibition value	-0.0076244	0.078692	-0.14286	0.963	0.923
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-3.4212	8.0403	-0.32140	0.952	0.673
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.55221	7.9799	0.014712	0.982	0.945
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.77513	8.2782	-0.016114	0.972	0.926
startle / PPI	average startle response to full pulse (120 dB)	-9.1042	42.765	-0.010509	0.937	0.833
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-9.2333	43.985	-0.0063051	0.927	0.835
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-11.402	39.101	-0.048358	0.867	0.772
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-4.7792	36.931	0.060987	0.954	0.898
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	-0.32068	1.6190	-0.19529	0.973	0.844
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	0.63634	1.2190	0.44203	0.918	0.605
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	2.9333	1.6808	1.0349	0.501	0.0905
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.060973	0.098194	-0.54168	0.921	0.539
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.0048877	0.090070	-0.14144	0.993	0.957
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.020190	0.098200	0.0042058	0.936	0.838
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	-10.358	43.359	-0.024522	0.924	0.813
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	-8.6187	44.516	0.0091075	0.931	0.848
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	-11.758	39.139	-0.049761	0.865	0.766
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	-7.7125	37.638	-0.0021017	0.919	0.839
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.00047657	0.092266	0.030129	0.999	0.996
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.013976	0.094050	0.0070096	0.956	0.883
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.041014	0.10063	0.12510	0.855	0.686
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	-28.869	156.91	0.013311	0.942	0.855
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	-66.623	160.94	-0.19958	0.840	0.682
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	-58.477	144.88	-0.13704	0.815	0.689
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	-31.265	140.49	-0.0035028	0.900	0.825
startle / PPI	maximum baseline movement during background noise	3.8604	3.7661	1.0865	0.775	0.313
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.49577	8.1898	0.10176	1.00	0.952
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	2.0756	8.5475	0.10739	0.931	0.810
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	3.0828	8.8711	0.14128	0.890	0.731
startle / PPI	maximum startle response to full pulse (120 dB)	-25.008	155.60	0.035737	0.951	0.873
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-67.929	159.72	-0.20959	0.833	0.673
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-56.829	144.67	-0.13280	0.819	0.697
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-24.588	138.86	0.030129	0.924	0.861
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	-0.46167	3.9697	-0.014712	0.978	0.908
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	2.4410	2.5685	0.67845	0.797	0.349
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	6.6771	3.7893	0.92827	0.455	0.0876

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

In this plot, data points are the computed genotype effect % vs. C57BL/6NJ controls, for all measured categorical phenotypes in JaxKOMP-EAP

Dimensions Width: × Height: px

Plot Options Group by Procedure

Include Sexes Data Both Females Males

Significance Threshold p-Value Threshold

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Procedure	JaxKOMP-EAP Trait	Sex	Trait Effect	P-value

eye morphology	anterior chamber depth	females	1.0 %	1.0
eye morphology	anterior chamber depth	males	0.0 %	1.0
eye morphology	anterior chamber depth	both	1.0 %	1.0
eye morphology	bulging eye	females	1.0 %	1.0
eye morphology	bulging eye	males	0.0 %	1.0
eye morphology	bulging eye	both	1.0 %	1.00
eye morphology	cornea	females	4.0 %	1.0
eye morphology	cornea	males	2.0 %	1.0
eye morphology	cornea	both	3.0 %	1.00
eye morphology	cornea opacity	females	5.0 %	1.00
eye morphology	cornea opacity	males	1.0 %	1.0
eye morphology	cornea opacity	both	3.0 %	1.00
eye morphology	cornea vascularization	females	3.0 %	1.0
eye morphology	cornea vascularization	males	1.0 %	1.0
eye morphology	cornea vascularization	both	2.0 %	1.00
eye morphology	corneal deposits	females	2.0 %	1.0
eye morphology	corneal deposits	males	1.0 %	1.0
eye morphology	corneal deposits	both	1.0 %	1.00
eye morphology	corneal mineralization	females	2.0 %	1.0
eye morphology	corneal mineralization	males	1.0 %	1.0
eye morphology	corneal mineralization	both	1.0 %	1.00
eye morphology	corneal scleralization	females	3.0 %	1.00
eye morphology	corneal scleralization	males	1.0 %	1.0
eye morphology	corneal scleralization	both	2.0 %	1.00
eye morphology	corneal ulcer	females	1.0 %	1.0
eye morphology	corneal ulcer	males	1.0 %	1.0
eye morphology	corneal ulcer	both	1.0 %	1.00
eye morphology	eye closure	females	1.0 %	1.00
eye morphology	eye closure	males	0.0 %	1.0
eye morphology	eye closure	both	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	females	2.0 %	1.00
eye morphology	eye hemorrhage or blood presence	males	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	both	1.0 %	1.00
eye morphology	eyelid morphology	females	1.0 %	1.0
eye morphology	eyelid morphology	males	0.0 %	1.0
eye morphology	eyelid morphology	both	1.0 %	1.0
eye morphology	eyes (present, absent)	females	1.0 %	1.0
eye morphology	eyes (present, absent)	males	0.0 %	1.0
eye morphology	eyes (present, absent)	both	0.0 %	1.0
eye morphology	fusion between cornea and lens	females	4.0 %	1.00
eye morphology	fusion between cornea and lens	males	2.0 %	1.0
eye morphology	fusion between cornea and lens	both	3.0 %	1.00
eye morphology	iris pigmentation	females	2.0 %	1.0
eye morphology	iris pigmentation	males	1.0 %	1.0
eye morphology	iris pigmentation	both	2.0 %	1.00
eye morphology	iris transillumination	females	2.0 %	1.00
eye morphology	iris transillumination	males	1.0 %	1.0
eye morphology	iris transillumination	both	1.0 %	1.00
eye morphology	irispupil	females	4.0 %	1.00
eye morphology	irispupil	males	3.0 %	1.0
eye morphology	irispupil	both	3.0 %	1.00
eye morphology	lacrimation	females	3.0 %	1.0
eye morphology	lacrimation	males	2.0 %	1.0
eye morphology	lacrimation	both	3.0 %	1.0
eye morphology	lens	females	10.0 %	1.00
eye morphology	lens	males	8.0 %	1.0
eye morphology	lens	both	9.0 %	1.0
eye morphology	lens opacity	females	9.0 %	1.0
eye morphology	lens opacity	males	6.0 %	1.0
eye morphology	lens opacity	both	7.0 %	1.00
eye morphology	narrow eye opening	females	2.0 %	1.0
eye morphology	narrow eye opening	males	1.0 %	1.0
eye morphology	narrow eye opening	both	1.0 %	1.0
eye morphology	optic disc	females	4.0 %	1.00
eye morphology	optic disc	males	2.0 %	1.0
eye morphology	optic disc	both	3.0 %	1.00
eye morphology	persistence of hyaloid vascular system	females	14.0 %	1.0
eye morphology	persistence of hyaloid vascular system	males	5.0 %	1.0
eye morphology	persistence of hyaloid vascular system	both	9.0 %	1.00
eye morphology	pupil dilation	females	2.0 %	1.0
eye morphology	pupil dilation	males	1.0 %	1.0
eye morphology	pupil dilation	both	2.0 %	1.0
eye morphology	pupil light response	females	2.0 %	1.00
eye morphology	pupil light response	males	1.0 %	1.0
eye morphology	pupil light response	both	2.0 %	1.00
eye morphology	pupil position	females	4.0 %	1.00
eye morphology	pupil position	males	3.0 %	1.0
eye morphology	pupil position	both	4.0 %	1.00
eye morphology	pupil shape	females	3.0 %	1.00
eye morphology	pupil shape	males	2.0 %	1.0
eye morphology	pupil shape	both	3.0 %	1.00
eye morphology	retina	females	10.0 %	1.0
eye morphology	retina	males	16.0 %	1.0
eye morphology	retina	both	13.0 %	1.0
eye morphology	retinal blood vessels	females	4.0 %	1.0
eye morphology	retinal blood vessels	males	2.0 %	1.0
eye morphology	retinal blood vessels	both	3.0 %	1.0
eye morphology	retinal blood vessels pattern	females	5.0 %	1.0
eye morphology	retinal blood vessels pattern	males	2.0 %	1.0
eye morphology	retinal blood vessels pattern	both	4.0 %	1.00
eye morphology	retinal blood vessels structure	females	4.0 %	1.00
eye morphology	retinal blood vessels structure	males	2.0 %	1.0
eye morphology	retinal blood vessels structure	both	3.0 %	1.00
eye morphology	retinal pigmentation	females	12.0 %	1.0
eye morphology	retinal pigmentation	males	14.0 %	1.0
eye morphology	retinal pigmentation	both	13.0 %	1.0
eye morphology	retinal structure	females	4.0 %	1.00
eye morphology	retinal structure	males	2.0 %	1.0
eye morphology	retinal structure	both	3.0 %	1.00
eye morphology	synechia	females	4.0 %	1.0
eye morphology	synechia	males	2.0 %	1.0
eye morphology	synechia	both	3.0 %	1.00
eye morphology	vitreous	females	4.0 %	1.00
eye morphology	vitreous	males	2.0 %	1.0
eye morphology	vitreous	both	3.0 %	1.00
SHIRPA	activity body position	females	1.0 %	1.0
SHIRPA	activity body position	males	2.0 %	1.0
SHIRPA	activity body position	both	1.0 %	1.00
SHIRPA	aggression	females	0.0 %	1.00
SHIRPA	aggression	males	1.0 %	1.0
SHIRPA	aggression	both	1.0 %	1.0
SHIRPA	body length	females	0.0 %	1.0
SHIRPA	body length	males	0.0 %	1.00
SHIRPA	body length	both	0.0 %	1.00
SHIRPA	body position	females	0.0 %	1.0
SHIRPA	body position	males	1.0 %	1.0
SHIRPA	body position	both	0.0 %	1.0
SHIRPA	body thickness	females	1.0 %	1.0
SHIRPA	body thickness	males	0.0 %	1.0
SHIRPA	body thickness	both	0.0 %	1.0
SHIRPA	coat color abdomen	females	3.0 %	1.00
SHIRPA	coat color abdomen	males	4.0 %	1.0
SHIRPA	coat color abdomen	both	4.0 %	1.0
SHIRPA	coat color back	females	0.0 %	1.0
SHIRPA	coat color back	males	0.0 %	1.00
SHIRPA	coat color back	both	0.0 %	1.00
SHIRPA	coat color head	females	0.0 %	1.0
SHIRPA	coat color head	males	0.0 %	1.00
SHIRPA	coat color head	both	0.0 %	1.0
SHIRPA	coat color pattern abdomen	females	1.0 %	1.0
SHIRPA	coat color pattern abdomen	males	1.0 %	1.0
SHIRPA	coat color pattern abdomen	both	1.0 %	1.0
SHIRPA	coat color pattern back	females	0.0 %	1.0
SHIRPA	coat color pattern back	males	0.0 %	1.00
SHIRPA	coat color pattern back	both	0.0 %	1.0
SHIRPA	coat color pattern head	females	0.0 %	1.0
SHIRPA	coat color pattern head	males	0.0 %	1.0
SHIRPA	coat color pattern head	both	0.0 %	1.00
SHIRPA	coat hair abdomen texture appearance	females	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	males	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	both	2.0 %	1.0
SHIRPA	coat hair back texture appearance	females	0.0 %	1.0
SHIRPA	coat hair back texture appearance	males	0.0 %	1.0
SHIRPA	coat hair back texture appearance	both	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	females	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	males	1.0 %	1.00
SHIRPA	coat hair distribution abdomen	both	1.0 %	1.00
SHIRPA	coat hair distribution back	females	0.0 %	1.0
SHIRPA	coat hair distribution back	males	0.0 %	1.0
SHIRPA	coat hair distribution back	both	0.0 %	1.0
SHIRPA	coat hair distribution head	females	12.0 %	0.0629
SHIRPA	coat hair distribution head	males	1.0 %	1.0
SHIRPA	coat hair distribution head	both	6.0 %	0.104
SHIRPA	coat hair head texture appearance	females	0.0 %	1.00
SHIRPA	coat hair head texture appearance	males	0.0 %	1.0
SHIRPA	coat hair head texture appearance	both	0.0 %	1.0
SHIRPA	contact righting	females	5.0 %	1.0
SHIRPA	contact righting	males	5.0 %	1.00
SHIRPA	contact righting	both	5.0 %	1.00
SHIRPA	ear morphology	females	0.0 %	1.0
SHIRPA	ear morphology	males	0.0 %	1.0
SHIRPA	ear morphology	both	0.0 %	1.0
SHIRPA	fat distribution	females	0.0 %	1.0
SHIRPA	fat distribution	males	0.0 %	1.0
SHIRPA	fat distribution	both	0.0 %	1.00
SHIRPA	forelimb digit number	females	0.0 %	1.00
SHIRPA	forelimb digit number	males	0.0 %	1.0
SHIRPA	forelimb digit number	both	0.0 %	1.00
SHIRPA	forelimb digit position	females	0.0 %	1.0
SHIRPA	forelimb digit position	males	0.0 %	1.0
SHIRPA	forelimb digit position	both	0.0 %	1.0
SHIRPA	forelimb digit shape	females	0.0 %	1.0
SHIRPA	forelimb digit shape	males	0.0 %	1.0
SHIRPA	forelimb digit shape	both	0.0 %	1.0
SHIRPA	forelimb digit size	females	0.0 %	1.0
SHIRPA	forelimb digit size	males	0.0 %	1.0
SHIRPA	forelimb digit size	both	0.0 %	1.0
SHIRPA	forelimb footpads	females	0.0 %	1.0
SHIRPA	forelimb footpads	males	0.0 %	1.0
SHIRPA	forelimb footpads	both	0.0 %	1.0
SHIRPA	forelimb nail length	females	0.0 %	1.0
SHIRPA	forelimb nail length	males	0.0 %	1.0
SHIRPA	forelimb nail length	both	0.0 %	1.0
SHIRPA	forelimb nail number	females	0.0 %	1.0
SHIRPA	forelimb nail number	males	0.0 %	1.0
SHIRPA	forelimb nail number	both	0.0 %	1.0
SHIRPA	forelimb nail position	females	0.0 %	1.0
SHIRPA	forelimb nail position	males	0.0 %	1.0
SHIRPA	forelimb nail position	both	0.0 %	1.0
SHIRPA	forelimb nail shape	females	0.0 %	1.0
SHIRPA	forelimb nail shape	males	0.0 %	1.0
SHIRPA	forelimb nail shape	both	0.0 %	1.0
SHIRPA	forelimbs position	females	0.0 %	1.0
SHIRPA	forelimbs position	males	0.0 %	1.0
SHIRPA	forelimbs position	both	0.0 %	1.0
SHIRPA	forelimbs shape	females	0.0 %	1.0
SHIRPA	forelimbs shape	males	0.0 %	1.0
SHIRPA	forelimbs shape	both	0.0 %	1.0
SHIRPA	forelimbs size	females	0.0 %	1.0
SHIRPA	forelimbs size	males	0.0 %	1.0
SHIRPA	forelimbs size	both	0.0 %	1.0
SHIRPA	forepaw position	females	0.0 %	1.0
SHIRPA	forepaw position	males	0.0 %	1.0
SHIRPA	forepaw position	both	0.0 %	1.0
SHIRPA	forepaw shape	females	0.0 %	1.0
SHIRPA	forepaw shape	males	0.0 %	1.0
SHIRPA	forepaw shape	both	0.0 %	1.0
SHIRPA	forepaw size	females	0.0 %	1.0
SHIRPA	forepaw size	males	0.0 %	1.0
SHIRPA	forepaw size	both	0.0 %	1.0
SHIRPA	gait (fluidity)	females	0.0 %	1.0
SHIRPA	gait (fluidity)	males	0.0 %	1.00
SHIRPA	gait (fluidity)	both	0.0 %	1.00
SHIRPA	genitalia morphology	females	0.0 %	1.00
SHIRPA	genitalia morphology	males	0.0 %	1.0
SHIRPA	genitalia morphology	both	0.0 %	1.00
SHIRPA	genitalia presence	females	0.0 %	1.0
SHIRPA	genitalia presence	males	0.0 %	1.0
SHIRPA	genitalia presence	both	0.0 %	1.0
SHIRPA	genitalia size	females	0.0 %	1.0
SHIRPA	genitalia size	males	0.0 %	1.0
SHIRPA	genitalia size	both	0.0 %	1.0
SHIRPA	head bobbing	females	0.0 %	1.0
SHIRPA	head bobbing	males	0.0 %	1.0
SHIRPA	head bobbing	both	0.0 %	1.0
SHIRPA	head morphology	females	0.0 %	1.0
SHIRPA	head morphology	males	0.0 %	1.00
SHIRPA	head morphology	both	0.0 %	1.0
SHIRPA	head size	females	0.0 %	1.0
SHIRPA	head size	males	0.0 %	1.0
SHIRPA	head size	both	0.0 %	1.00
SHIRPA	hindlimb digit number	females	1.0 %	1.00
SHIRPA	hindlimb digit number	males	0.0 %	1.0
SHIRPA	hindlimb digit number	both	0.0 %	1.00
SHIRPA	hindlimb digit position	females	0.0 %	1.0
SHIRPA	hindlimb digit position	males	0.0 %	1.0
SHIRPA	hindlimb digit position	both	0.0 %	1.0
SHIRPA	hindlimb digit shape	females	0.0 %	1.0
SHIRPA	hindlimb digit shape	males	12.0 %	0.0206
SHIRPA	hindlimb digit shape	both	6.0 %	0.0349
SHIRPA	hindlimb digit size	females	0.0 %	1.00
SHIRPA	hindlimb digit size	males	0.0 %	1.0
SHIRPA	hindlimb digit size	both	0.0 %	1.00
SHIRPA	hindlimb nail length	females	0.0 %	1.0
SHIRPA	hindlimb nail length	males	0.0 %	1.0
SHIRPA	hindlimb nail length	both	0.0 %	1.00
SHIRPA	hindlimb nail number	females	0.0 %	1.0
SHIRPA	hindlimb nail number	males	1.0 %	1.0
SHIRPA	hindlimb nail number	both	0.0 %	1.00
SHIRPA	hindlimb nail position	females	0.0 %	1.0
SHIRPA	hindlimb nail position	males	0.0 %	1.0
SHIRPA	hindlimb nail position	both	0.0 %	1.0
SHIRPA	hindlimb nail shape	females	0.0 %	1.0
SHIRPA	hindlimb nail shape	males	0.0 %	1.0
SHIRPA	hindlimb nail shape	both	0.0 %	1.0
SHIRPA	hindlimbs footpads	females	0.0 %	1.0
SHIRPA	hindlimbs footpads	males	0.0 %	1.0
SHIRPA	hindlimbs footpads	both	0.0 %	1.0
SHIRPA	hindlimbs position	females	0.0 %	1.0
SHIRPA	hindlimbs position	males	0.0 %	1.0
SHIRPA	hindlimbs position	both	0.0 %	1.0
SHIRPA	hindlimbs shape	females	0.0 %	1.0
SHIRPA	hindlimbs shape	males	0.0 %	1.0
SHIRPA	hindlimbs shape	both	0.0 %	1.0
SHIRPA	hindlimbs size	females	0.0 %	1.0
SHIRPA	hindlimbs size	males	0.0 %	1.0
SHIRPA	hindlimbs size	both	0.0 %	1.0
SHIRPA	hindpaw position	females	0.0 %	1.0
SHIRPA	hindpaw position	males	0.0 %	1.0
SHIRPA	hindpaw position	both	0.0 %	1.0
SHIRPA	hindpaw shape	females	0.0 %	1.0
SHIRPA	hindpaw shape	males	0.0 %	1.0
SHIRPA	hindpaw shape	both	0.0 %	1.0
SHIRPA	hindpaw size	females	0.0 %	1.0
SHIRPA	hindpaw size	males	0.0 %	1.0
SHIRPA	hindpaw size	both	0.0 %	1.0
SHIRPA	limb grasp	females	9.0 %	1.00
SHIRPA	limb grasp	males	6.0 %	1.0
SHIRPA	limb grasp	both	7.0 %	0.624
SHIRPA	lower lip morphology	females	0.0 %	1.0
SHIRPA	lower lip morphology	males	0.0 %	1.0
SHIRPA	lower lip morphology	both	0.0 %	1.0
SHIRPA	lower teeth appearance	females	0.0 %	1.0
SHIRPA	lower teeth appearance	males	0.0 %	1.00
SHIRPA	lower teeth appearance	both	0.0 %	1.00
SHIRPA	mouth morphology	females	0.0 %	1.0
SHIRPA	mouth morphology	males	0.0 %	1.00
SHIRPA	mouth morphology	both	0.0 %	1.00
SHIRPA	salivation	females	0.0 %	1.0
SHIRPA	salivation	males	0.0 %	1.0
SHIRPA	salivation	both	0.0 %	1.0
SHIRPA	skin color back paws	females	0.0 %	1.0
SHIRPA	skin color back paws	males	0.0 %	1.0
SHIRPA	skin color back paws	both	0.0 %	1.0
SHIRPA	skin color ear	females	0.0 %	1.0
SHIRPA	skin color ear	males	0.0 %	1.0
SHIRPA	skin color ear	both	0.0 %	1.0
SHIRPA	skin color front paws	females	0.0 %	1.0
SHIRPA	skin color front paws	males	0.0 %	1.0
SHIRPA	skin color front paws	both	0.0 %	1.0
SHIRPA	skin color snout	females	0.0 %	1.0
SHIRPA	skin color snout	males	0.0 %	1.0
SHIRPA	skin color snout	both	0.0 %	1.0
SHIRPA	skin color tail	females	0.0 %	1.0
SHIRPA	skin color tail	males	0.0 %	1.0
SHIRPA	skin color tail	both	0.0 %	1.0
SHIRPA	skin color whole body	females	0.0 %	1.0
SHIRPA	skin color whole body	males	0.0 %	1.0
SHIRPA	skin color whole body	both	0.0 %	1.0
SHIRPA	skin texture back paw	females	0.0 %	1.0
SHIRPA	skin texture back paw	males	0.0 %	1.0
SHIRPA	skin texture back paw	both	0.0 %	1.0
SHIRPA	skin texture ear	females	0.0 %	1.0
SHIRPA	skin texture ear	males	0.0 %	1.0
SHIRPA	skin texture ear	both	0.0 %	1.0
SHIRPA	skin texture front paws	females	0.0 %	1.0
SHIRPA	skin texture front paws	males	0.0 %	1.0
SHIRPA	skin texture front paws	both	0.0 %	1.0
SHIRPA	skin texture snout	females	0.0 %	1.0
SHIRPA	skin texture snout	males	0.0 %	1.0
SHIRPA	skin texture snout	both	0.0 %	1.0
SHIRPA	skin texture tail	females	0.0 %	1.0
SHIRPA	skin texture tail	males	0.0 %	1.0
SHIRPA	skin texture tail	both	0.0 %	1.0
SHIRPA	skin texture whole body	females	0.0 %	1.0
SHIRPA	skin texture whole body	males	0.0 %	1.00
SHIRPA	skin texture whole body	both	0.0 %	1.00
SHIRPA	snout size	females	0.0 %	1.0
SHIRPA	snout size	males	1.0 %	1.0
SHIRPA	snout size	both	0.0 %	1.0
SHIRPA	startle response	females	0.0 %	1.00
SHIRPA	startle response	males	0.0 %	1.00
SHIRPA	startle response	both	0.0 %	1.00
SHIRPA	tail curvature	females	0.0 %	1.00
SHIRPA	tail curvature	males	0.0 %	1.0
SHIRPA	tail curvature	both	0.0 %	1.0
SHIRPA	tail elevation	females	1.0 %	1.00
SHIRPA	tail elevation	males	2.0 %	1.0
SHIRPA	tail elevation	both	1.0 %	1.0
SHIRPA	tail length	females	0.0 %	1.0
SHIRPA	tail length	males	0.0 %	1.0
SHIRPA	tail length	both	0.0 %	1.00
SHIRPA	tail morphology	females	0.0 %	1.00
SHIRPA	tail morphology	males	0.0 %	1.0
SHIRPA	tail morphology	both	0.0 %	1.00
SHIRPA	tail presence	females	0.0 %	1.0
SHIRPA	tail presence	males	0.0 %	1.0
SHIRPA	tail presence	both	0.0 %	1.0
SHIRPA	tail shape	females	0.0 %	1.0
SHIRPA	tail shape	males	0.0 %	1.0
SHIRPA	tail shape	both	0.0 %	1.00
SHIRPA	tail thickness	females	0.0 %	1.0
SHIRPA	tail thickness	males	0.0 %	1.0
SHIRPA	tail thickness	both	0.0 %	1.0
SHIRPA	teeth presence	females	0.0 %	1.0
SHIRPA	teeth presence	males	0.0 %	1.00
SHIRPA	teeth presence	both	0.0 %	1.00
SHIRPA	transfer arousal	females	1.0 %	1.0
SHIRPA	transfer arousal	males	2.0 %	1.00
SHIRPA	transfer arousal	both	1.0 %	1.0
SHIRPA	tremor	females	0.0 %	1.0
SHIRPA	tremor	males	0.0 %	1.0
SHIRPA	tremor	both	0.0 %	1.00
SHIRPA	trunk curl	females	0.0 %	1.00
SHIRPA	trunk curl	males	0.0 %	1.0
SHIRPA	trunk curl	both	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	females	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	males	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	both	0.0 %	1.00
SHIRPA	upper lip morphology	females	0.0 %	1.0
SHIRPA	upper lip morphology	males	0.0 %	1.0
SHIRPA	upper lip morphology	both	0.0 %	1.0
SHIRPA	upper teeth appearance	females	0.0 %	1.0
SHIRPA	upper teeth appearance	males	0.0 %	1.0
SHIRPA	upper teeth appearance	both	0.0 %	1.00
SHIRPA	vibrissae appearance	females	11.0 %	0.141
SHIRPA	vibrissae appearance	males	1.0 %	1.0
SHIRPA	vibrissae appearance	both	5.0 %	0.176
SHIRPA	vibrissae presence	females	2.0 %	1.00
SHIRPA	vibrissae presence	males	1.0 %	1.0
SHIRPA	vibrissae presence	both	2.0 %	1.0
SHIRPA	vocalization	females	2.0 %	1.00
SHIRPA	vocalization	males	2.0 %	1.00
SHIRPA	vocalization	both	2.0 %	1.0

GENOTYPE CORRELATION PLOT

Correlate Rufy1^em1(IMPC)J/Mmjax -/- with genotype: