MPD: JaxKOMP-EAP genotype: Cstf1<sup>em1(IMPC)J</sup>/Mmjax -/+

JaxKOMP-EAP effect sizes: Cstf1^em1(IMPC)J/Mmjax -/+ Gene Cstf1

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

In this plot, data points are the computed genotype effect size vs. C57BL/6NJ controls, for all measured numeric phenotypes in JaxKOMP-EAP

Dimensions Width: × Height: px

Plot Options Group by Procedure Standard Error Show Effect Sizes RankZ

Significance Threshold p-Value Threshold Adjusted Unadjusted

Download Plot

Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value

ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	5.6286	3.1288	1.2526	0.567	0.146
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	11.865	3.6200	1.7759	0.358	0.0306
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	2.5240	4.8929	0.35150	0.871	0.633
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	8.8702	5.6085	1.2413	0.578	0.189
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	2.6442	6.2104	0.38049	0.882	0.692
body composition	body length	0.033088	0.043886	0.66976	0.731	0.457
body composition	body weight (at time of DXA)	-1.4386	0.74726	-0.91881	0.197	0.0637
body composition	bone area, whole body scan, head excluded	0.13073	0.11776	0.74474	0.539	0.276
body composition	bone mineral content of whole body scan, head excluded	0.018336	0.0097581	1.1786	0.265	0.0703
body composition	bone mineral content to body weight ratio	0.00094318	0.00038243	1.3759	0.116	0.0198
body composition	bone mineral density of whole body scan, head excluded	0.0012970	0.00068243	1.3651	0.277	0.0673
body composition	fat tissue mass of whole body scan, head excluded	-0.73797	0.37270	-1.3866	0.224	0.0573
body composition	fat tissue mass to body weight ratio	-0.029734	0.012530	-1.3152	0.120	0.0243
body composition	lean tissue mass of whole body scan, head excluded	0.40912	0.45119	0.69868	0.671	0.372
body composition	lean tissue mass to body weight ratio	0.031897	0.011529	1.5598	0.0896	0.00960
body composition	percent fat, whole body scan, head excluded	-2.9246	1.1667	-1.3901	0.106	0.0178
body composition	ratio of soft-tissue attenuation coefficients	0.0034071	0.0013197	1.4488	0.0938	0.0150
body composition	tissue area	-0.48155	0.25683	-1.3113	0.293	0.0709
body composition	total tissue mass, whole body scan, head excluded	-0.47270	0.47103	-1.4046	0.576	0.324
clinical blood chemistry	alanine transaminase (plasma ALT)	1.6017	4.2301	0.15435	0.917	0.708
clinical blood chemistry	albumin (plasma Alb)	0.25751	0.55347	0.40273	0.859	0.645
clinical blood chemistry	alkaline phosphatase (plasma ALP)	-3.1736	4.4726	-1.0769	0.709	0.484
clinical blood chemistry	aspartate transaminase (plasma AST)	3.8884	7.5476	0.19692	0.844	0.610
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	0.041306	0.10639	0.14959	0.911	0.701
clinical blood chemistry	blood urea nitrogen (BUN)	-0.74717	1.4108	-0.32600	0.800	0.601
clinical blood chemistry	calcium (plasma Ca)	-0.25212	0.082344	-1.4404	0.0414	0.00494
clinical blood chemistry	creatinine (plasma)	0.0068843	0.016613	0.26560	0.825	0.682
clinical blood chemistry	glucose (plasma GLU, no fast)	13.418	17.150	0.81147	0.643	0.441
clinical blood chemistry	HDL cholesterol (plasma HDL)	-3.7860	3.5745	-1.1078	0.604	0.299
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	-0.030921	0.016406	-1.7807	0.344	0.0703
clinical blood chemistry	phosphorus (plasma phosphate)	-1.6214	0.41198	-2.0108	0.0171	0.000525
clinical blood chemistry	total bilirubin (plasma TBIL)	0.019831	0.0078506	1.1948	0.161	0.0175
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	-0.62101	4.9076	-0.34135	0.964	0.900
clinical blood chemistry	total protein (plasma TP)	-0.20002	0.58499	-0.21578	0.879	0.735
clinical blood chemistry	triglyceride (plasma TG, no fast)	8.0362	14.514	0.66019	0.798	0.584
ERG v2.0	left eye a-wave amplitude (Photopic)	2.2315	1.4850	0.73798	0.556	0.155
ERG v2.0	left eye a-wave amplitude (Scotopic)	-0.57869	22.076	-0.18001	0.986	0.979
ERG v2.0	left eye a-wave implicit timing (Photopic)	-3.5485	1.7944	-1.4733	0.533	0.0680
ERG v2.0	left eye a-wave implicit timing (Scotopic)	-0.19164	0.47671	-0.14341	0.885	0.694
ERG v2.0	left eye b-wave amplitude (Photopic)	-18.652	10.032	-1.6199	0.454	0.0858
ERG v2.0	left eye b-wave amplitude (Scotopic)	-6.5701	59.695	0.019283	0.996	0.914
ERG v2.0	left eye b-wave implicit timing (Photopic)	1.4131	1.8026	0.47951	0.729	0.447
ERG v2.0	left eye b-wave implicit timing (Scotopic)	-19.512	12.098	-1.7065	0.577	0.131
ERG v2.0	left eye c-wave amplitude (Scotopic)	186.86	79.765	2.6208	0.369	0.0357
ERG v2.0	left eye c-wave implicit timing (Scotopic)	-77.204	72.061	-0.81222	0.694	0.303
ERG v2.0	left eye FO-like wave amplitude (Scotopic)	-339.15	103.20	-2.3751	0.128	0.00590
ERG v2.0	left eye FO-like wave implicit timing (Scotopic)	-154.94	181.88	-0.44082	0.844	0.410
ERG v2.0	right eye a-wave amplitude (Photopic)	3.6519	1.5152	1.2168	0.344	0.0303
ERG v2.0	right eye a-wave amplitude (Scotopic)	-7.7643	28.071	-0.56135	0.952	0.786
ERG v2.0	right eye a-wave implicit timing (Photopic)	0.17757	1.9693	0.063397	0.996	0.930
ERG v2.0	right eye a-wave implicit timing (Scotopic)	-2.2642	1.2189	-1.8686	0.472	0.0860
ERG v2.0	right eye b-wave amplitude (Photopic)	-15.759	7.3867	-1.4584	0.363	0.0511
ERG v2.0	right eye b-wave amplitude (Scotopic)	-83.736	49.209	-1.1611	0.587	0.111
ERG v2.0	right eye b-wave implicit timing (Photopic)	2.4217	2.3343	0.76717	0.686	0.318
ERG v2.0	right eye b-wave implicit timing (Scotopic)	5.7396	9.8529	0.68836	0.874	0.570
ERG v2.0	right eye c-wave amplitude (Scotopic)	112.74	65.130	2.0592	0.540	0.107
ERG v2.0	right eye c-wave implicit timing (Scotopic)	46.902	52.740	0.52756	0.785	0.389
ERG v2.0	right eye FO-like wave amplitude (Scotopic)	-187.35	81.669	-2.3751	0.393	0.0391
ERG v2.0	right eye FO-like wave implicit timing (Scotopic)	511.44	184.51	1.7832	0.359	0.0150
glucose tolerance test	amount glucose injected	-2.1726	4.5827	-0.28930	0.889	0.668
glucose tolerance test	plasma glucose, 0min	-2.2197	17.763	-0.45293	0.958	0.908
glucose tolerance test	plasma glucose, 15min	-38.342	71.252	-0.92728	0.861	0.628
glucose tolerance test	plasma glucose, 30min	-36.988	71.121	-1.0061	0.843	0.639
glucose tolerance test	plasma glucose, 60min	-17.669	34.672	-0.62281	0.865	0.645
glucose tolerance test	plasma glucose, 120min	7.0724	18.042	0.33420	0.898	0.721
grip strength	body weight (at time of grip strength test)	-0.77886	0.48320	-0.50190	0.266	0.117
grip strength	forelimb and hindlimb grip strength (mean of trials), average	-14.634	6.2271	-0.75996	0.102	0.0258
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	-0.60518	0.28870	-0.70303	0.157	0.0449
grip strength	forelimb and hindlimb grip strength by trial, trial1	-13.510	7.1822	-0.65187	0.271	0.0701
grip strength	forelimb and hindlimb grip strength by trial, trial2	-12.467	8.5724	-0.55092	0.390	0.157
grip strength	forelimb and hindlimb grip strength by trial, trial3	-15.962	8.7955	-0.83584	0.282	0.0796
grip strength	forelimb grip strength (mean of trials), average	-6.2469	5.4710	-0.52740	0.528	0.263
grip strength	forelimb grip strength (mean of trials), average normalized to bw	-0.23195	0.24611	-0.36212	0.629	0.354
grip strength	forelimb grip strength by trial, trial1	-7.2245	6.1264	-0.57988	0.606	0.248
grip strength	forelimb grip strength by trial, trial2	-2.6742	6.0774	-0.078503	0.878	0.663
grip strength	forelimb grip strength by trial, trial3	-7.3741	6.6306	-0.56619	0.593	0.275
heart weight	heart weight, normalized to body weight	0.074720	0.12334	-0.17452	0.729	0.548
heart weight	heart weight, weight	7.7657	4.0041	0.64052	0.205	0.0594
hematology	basophil differential (percent of total WBC)	-0.048938	0.064111	-0.70145	0.802	0.450
hematology	eosinophil differential (percent of total WBC)	-0.16552	0.20942	-0.39646	0.789	0.434
hematology	hematocrit (HCT)	0.83954	0.46075	0.59507	0.321	0.0768
hematology	lymphocyte differential (percent of total WBC)	4.5584	2.8984	1.4897	0.364	0.125
hematology	mean corpuscular hemoglobin (CHr)	0.19349	0.070379	1.3551	0.0532	0.00928
hematology	mean platelet volume (MPV)	0.021338	0.040807	-0.026757	0.789	0.604
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	0.059789	0.12907	0.16373	0.866	0.646
hematology	mean RBC corpuscular volume (MCV)	0.52648	0.20689	0.90116	0.0796	0.0154
hematology	measured hemoglobin (mHGB)	0.26689	0.15590	0.46855	0.353	0.0955
hematology	monocyte differential (percent of total WBC)	-0.77804	0.59828	-1.4455	0.561	0.202
hematology	neutrophil differential (percent of total WBC)	-3.0737	2.3301	-1.1889	0.445	0.196
hematology	platelet count (PLT; units per volume x 10³)	-37.542	48.524	-0.45232	0.753	0.444
hematology	RBC corpuscular distribution width (RDW)	0.22104	0.15090	0.79714	0.398	0.152
hematology	red blood cell count (RBC; per volume x 10⁶)	0.067306	0.10972	-0.047907	0.755	0.543
hematology	reticulocyte count (Retic; units per volume x 10⁹)	30.761	17.670	1.2831	0.433	0.0903
hematology	reticulocyte differential (percent of total RBC)	0.28971	0.17257	1.2936	0.441	0.102
hematology	white blood cell count (WBC; units per volume x 10³)	-0.19974	0.63595	0.039646	0.866	0.755
holeboard	number of hole pokes by individual hole number, 20 min test, 1	0.050000	0.80319	0.092124	0.980	0.951
holeboard	number of hole pokes by individual hole number, 20 min test, 2	-0.38750	0.52933	-0.49652	0.860	0.468
holeboard	number of hole pokes by individual hole number, 20 min test, 3	-0.43823	0.60433	-0.67079	0.864	0.472
holeboard	number of hole pokes by individual hole number, 20 min test, 4	-0.83215	0.88563	-0.76697	0.774	0.352
holeboard	number of hole pokes by individual hole number, 20 min test, 5	-0.75000	0.58166	-1.1266	0.700	0.203
holeboard	number of hole pokes by individual hole number, 20 min test, 6	-0.45000	0.25585	-1.2800	0.645	0.0847
holeboard	number of hole pokes by individual hole number, 20 min test, 7	0.25127	0.37691	0.66550	0.919	0.508
holeboard	number of hole pokes by individual hole number, 20 min test, 8	0.33980	0.46345	0.71151	0.867	0.467
holeboard	number of hole pokes by individual hole number, 20 min test, 9	-0.82067	0.48513	-1.3026	0.531	0.0969
holeboard	number of hole pokes by individual hole number, 20 min test, 10	0.14443	0.37280	0.44375	0.951	0.700
holeboard	number of hole pokes by individual hole number, 20 min test, 11	-0.40000	0.38446	-1.0676	0.807	0.303
holeboard	number of hole pokes by individual hole number, 20 min test, 12	-0.26299	0.48905	-0.36559	0.898	0.593
holeboard	number of hole pokes by individual hole number, 20 min test, 13	0.31780	0.85563	0.40008	0.922	0.712
holeboard	number of hole pokes by individual hole number, 20 min test, 14	0.39450	0.58932	0.68405	0.845	0.506
holeboard	number of hole pokes by individual hole number, 20 min test, 15	0.38747	0.46284	0.67979	0.815	0.406
holeboard	number of hole pokes by individual hole number, 20 min test, 16	-0.63808	0.60718	-0.50668	0.704	0.298
holeboard	total number of hole pokes, 20 min test	-3.7050	5.1165	-0.42764	0.715	0.472
light / dark	latency to enter dark zone, 20 min test	2.8805	28.166	-0.063587	0.974	0.919
light / dark	number of transitions between light and dark zones, 20 min test	-2.9143	3.7916	-0.17942	0.721	0.446
light / dark	percentage of total time in dark zone, 20 min test	-2.3131	4.3377	-0.29067	0.849	0.596
light / dark	percentage of total time in light zone, 20 min test	2.3131	4.3377	0.28644	0.848	0.596
light / dark	time mobile in dark zone, 20 min test	0.043526	3.4894	-0.10293	0.997	0.990
light / dark	time mobile in light zone, 20 min test	4.8153	3.9473	0.079853	0.486	0.228
light / dark	time spent in dark zone, 20 min test	-29.106	49.897	-0.23052	0.855	0.562
light / dark	time spent in light zone, 20 min test	29.107	49.897	0.23052	0.855	0.562
open field	average speed in center of arena, 20 min test	0.11789	0.34754	0.11775	0.906	0.736
open field	average speed in periphery of arena, 20 min test	0.40722	0.13072	0.99164	0.0292	0.00354
open field	distance traveled habituation ratio, 20 min test	-6.1465	8.0942	-0.48944	0.736	0.453
open field	distance traveled in center of arena, 20 min test	176.91	109.93	0.75555	0.330	0.116
open field	distance traveled in periphery of arena, 20 min test	240.51	144.89	0.48793	0.295	0.105
open field	distance traveled slope, 20 min test	-3.8572	7.7395	-0.28929	0.844	0.621
open field	distance traveled, 20 min test, 1st 5min	206.03	64.948	1.1913	0.0294	0.00309
open field	distance traveled, 20 min test, 2nd 5min	49.688	57.751	0.053057	0.638	0.395
open field	distance traveled, 20 min test, 3rd 5min	93.923	55.581	0.59203	0.286	0.0995
open field	distance traveled, 20 min test, 4th 5min	145.55	66.738	1.0788	0.162	0.0356
open field	number of clockwise revolution episodes, 20 min test	1.8046	1.1304	0.65189	0.447	0.119
open field	number of counter-clockwise revolution episodes, 20 min test	4.3595	1.5587	1.6733	0.0959	0.00823
open field	number of rears in 5 min bins, 20 min test, 1st 5min	9.6585	2.7050	2.0920	0.0232	0.00101
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	3.6890	4.0788	0.59844	0.650	0.372
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	2.9790	4.2116	0.39902	0.728	0.484
open field	number of rears in 5 min bins, 20 min test, 4th 5min	4.6076	3.8596	0.67913	0.513	0.240
open field	percentage of total time in center of arena, 20 min test	5.4978	3.1792	0.98726	0.375	0.0921
open field	percentage of total time in center of arena, slope, 20 min test	0.45125	1.8970	0.37443	0.957	0.813
open field	percentage of total time in center, habituation ratio, 20 min test	0.35577	1.9756	0.30472	0.967	0.858
open field	percentage of total time in corners of arena, 20 min test	-8.5344	2.9199	-1.2655	0.0845	0.00589
open field	percentage of total time in corners, habituation ratio, 20 min test	-1.7720	2.0233	-1.1007	0.843	0.387
open field	percentage of total time in corners, slope, 20 min test	-1.3998	2.0116	-0.95711	0.881	0.491
open field	permanence time in center of arena, 20 min test	65.962	38.154	0.98726	0.375	0.0922
open field	permanence time in corners of arena, 20 min test	-102.42	35.041	-1.2655	0.0845	0.00589
open field	permanence time in periphery of arena, 20 min test	-65.968	38.154	-0.98945	0.375	0.0921
open field	total distance traveled, 20 min test	410.31	202.67	0.66734	0.168	0.0502
open field	total number of rears, 20 min test	20.374	12.729	1.0622	0.326	0.118
open field	whole arena average speed, 20 min test	0.34095	0.16878	0.66065	0.169	0.0507
open field	whole arena resting time, 20 min test	-9.4266	27.344	0.28090	0.841	0.732
open field	whole arena time spent mobile, 20 min test	3.2735	5.0549	-0.39031	0.705	0.521
open field	whole arena time spent vertical, 20 min test	-1.4737	7.4250	-0.22681	0.936	0.844
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	-1.8780	1.4156	-0.59736	0.517	0.195
startle / PPI	average baseline movement during background noise	-1.0793	1.3087	-0.75267	0.867	0.414
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	0.0085955	0.068803	-0.027326	0.957	0.901
startle / PPI	average of each corrected percent pre-pulse inhibition value	-0.013936	0.065091	-0.20840	0.929	0.831
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-4.5420	7.3326	-0.44203	0.910	0.539
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-4.5702	7.4514	-0.48257	0.807	0.543
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	3.9361	5.5900	0.31551	0.758	0.485
startle / PPI	average startle response to full pulse (120 dB)	5.4061	32.809	0.33175	0.954	0.870
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	13.697	33.255	0.48730	0.841	0.682
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	4.2996	29.500	0.27453	0.934	0.885
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-28.128	23.317	-0.49204	0.455	0.234
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	-0.17760	1.0709	-0.055373	0.978	0.869
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	2.5854	1.3373	1.3339	0.537	0.0595
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	1.1014	1.9466	0.34213	0.870	0.574
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.034360	0.092596	-0.26436	0.941	0.712
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.0078558	0.074432	-0.020341	0.976	0.916
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.030648	0.070734	0.081401	0.852	0.667
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	5.5454	32.768	0.33027	0.947	0.866
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	13.623	33.246	0.49362	0.846	0.684
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	1.7249	29.374	0.21533	0.975	0.953
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	-20.760	24.123	-0.30522	0.601	0.394
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.0097580	0.10050	-0.062391	0.994	0.923
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.0055056	0.084052	-0.12792	0.978	0.948
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.050817	0.068968	0.20041	0.702	0.465
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	45.223	115.17	0.46220	0.863	0.696
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	55.115	121.38	0.48414	0.821	0.652
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	54.634	110.53	0.49837	0.769	0.624
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	-72.158	86.391	-0.26436	0.612	0.408
startle / PPI	maximum baseline movement during background noise	-2.5887	3.2525	-0.71055	0.836	0.430
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-3.1677	7.6021	-0.26436	0.950	0.679
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-2.1732	7.8157	-0.26291	0.915	0.782
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	6.2044	5.8637	0.44203	0.584	0.296
startle / PPI	maximum startle response to full pulse (120 dB)	44.944	114.92	0.46065	0.865	0.698
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	56.050	121.21	0.48888	0.815	0.646
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	59.235	110.74	0.52553	0.759	0.595
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-72.409	86.057	-0.27453	0.610	0.405
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	0.31082	2.6136	0.21963	0.978	0.906
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	5.5905	3.0131	1.2717	0.555	0.0701
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	-0.73638	5.4300	-0.32288	0.976	0.893

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

In this plot, data points are the computed genotype effect % vs. C57BL/6NJ controls, for all measured categorical phenotypes in JaxKOMP-EAP

Dimensions Width: × Height: px

Plot Options Group by Procedure

Significance Threshold p-Value Threshold

Download Plot

Procedure	JaxKOMP-EAP Trait	Trait Effect	P-value

eye morphology	anterior chamber depth	1.0 %	1.0
eye morphology	bulging eye	1.0 %	1.00
eye morphology	cornea	3.0 %	1.00
eye morphology	cornea opacity	3.0 %	1.00
eye morphology	cornea vascularization	2.0 %	1.00
eye morphology	corneal deposits	1.0 %	1.00
eye morphology	corneal mineralization	1.0 %	1.00
eye morphology	corneal scleralization	2.0 %	1.00
eye morphology	corneal ulcer	1.0 %	1.00
eye morphology	eye closure	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	1.0 %	1.00
eye morphology	eyelid morphology	1.0 %	1.0
eye morphology	eyes (present, absent)	0.0 %	1.0
eye morphology	fusion between cornea and lens	3.0 %	1.00
eye morphology	iris pigmentation	2.0 %	1.00
eye morphology	iris transillumination	1.0 %	1.00
eye morphology	irispupil	3.0 %	1.00
eye morphology	lacrimation	6.0 %	0.106
eye morphology	lens	9.0 %	1.0
eye morphology	lens opacity	3.0 %	0.703
eye morphology	narrow eye opening	1.0 %	1.0
eye morphology	optic disc	3.0 %	1.00
eye morphology	persistence of hyaloid vascular system	9.0 %	1.00
eye morphology	pupil dilation	2.0 %	1.0
eye morphology	pupil light response	2.0 %	1.00
eye morphology	pupil position	4.0 %	1.00
eye morphology	pupil shape	3.0 %	1.00
eye morphology	retina	7.0 %	0.801
eye morphology	retinal blood vessels	3.0 %	1.0
eye morphology	retinal blood vessels pattern	4.0 %	1.00
eye morphology	retinal blood vessels structure	3.0 %	1.00
eye morphology	retinal pigmentation	13.0 %	1.0
eye morphology	retinal structure	3.0 %	1.00
eye morphology	synechia	3.0 %	1.00
eye morphology	vitreous	3.0 %	1.00
SHIRPA	activity body position	1.0 %	1.00
SHIRPA	aggression	1.0 %	1.0
SHIRPA	body length	0.0 %	1.00
SHIRPA	body position	0.0 %	1.0
SHIRPA	body thickness	0.0 %	1.0
SHIRPA	coat color abdomen	4.0 %	1.0
SHIRPA	coat color back	0.0 %	1.00
SHIRPA	coat color head	0.0 %	1.0
SHIRPA	coat color pattern abdomen	1.0 %	1.0
SHIRPA	coat color pattern back	0.0 %	1.0
SHIRPA	coat color pattern head	0.0 %	1.00
SHIRPA	coat hair abdomen texture appearance	2.0 %	1.0
SHIRPA	coat hair back texture appearance	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	1.0 %	1.00
SHIRPA	coat hair distribution back	0.0 %	1.0
SHIRPA	coat hair distribution head	1.0 %	1.0
SHIRPA	coat hair head texture appearance	0.0 %	1.0
SHIRPA	contact righting	5.0 %	1.00
SHIRPA	ear morphology	0.0 %	1.0
SHIRPA	fat distribution	0.0 %	1.00
SHIRPA	forelimb digit number	0.0 %	1.00
SHIRPA	forelimb digit position	0.0 %	1.0
SHIRPA	forelimb digit shape	0.0 %	1.0
SHIRPA	forelimb digit size	0.0 %	1.0
SHIRPA	forelimb footpads	0.0 %	1.0
SHIRPA	forelimb nail length	0.0 %	1.0
SHIRPA	forelimb nail number	0.0 %	1.0
SHIRPA	forelimb nail position	0.0 %	1.0
SHIRPA	forelimb nail shape	0.0 %	1.0
SHIRPA	forelimbs position	0.0 %	1.0
SHIRPA	forelimbs shape	0.0 %	1.0
SHIRPA	forelimbs size	0.0 %	1.0
SHIRPA	forepaw position	0.0 %	1.0
SHIRPA	forepaw shape	0.0 %	1.0
SHIRPA	forepaw size	0.0 %	1.0
SHIRPA	gait (fluidity)	0.0 %	1.00
SHIRPA	genitalia morphology	0.0 %	1.00
SHIRPA	genitalia presence	0.0 %	1.0
SHIRPA	genitalia size	6.0 %	0.0118
SHIRPA	head bobbing	0.0 %	1.0
SHIRPA	head morphology	0.0 %	1.0
SHIRPA	head size	0.0 %	1.00
SHIRPA	hindlimb digit number	0.0 %	1.00
SHIRPA	hindlimb digit position	0.0 %	1.0
SHIRPA	hindlimb digit shape	0.0 %	1.0
SHIRPA	hindlimb digit size	0.0 %	1.00
SHIRPA	hindlimb nail length	0.0 %	1.00
SHIRPA	hindlimb nail number	0.0 %	1.00
SHIRPA	hindlimb nail position	0.0 %	1.0
SHIRPA	hindlimb nail shape	0.0 %	1.0
SHIRPA	hindlimbs footpads	0.0 %	1.0
SHIRPA	hindlimbs position	0.0 %	1.0
SHIRPA	hindlimbs shape	0.0 %	1.0
SHIRPA	hindlimbs size	0.0 %	1.0
SHIRPA	hindpaw position	0.0 %	1.0
SHIRPA	hindpaw shape	0.0 %	1.0
SHIRPA	hindpaw size	0.0 %	1.0
SHIRPA	limb grasp	7.0 %	0.624
SHIRPA	lower lip morphology	0.0 %	1.0
SHIRPA	lower teeth appearance	0.0 %	1.00
SHIRPA	mouth morphology	0.0 %	1.00
SHIRPA	salivation	0.0 %	1.0
SHIRPA	skin color back paws	0.0 %	1.0
SHIRPA	skin color ear	0.0 %	1.0
SHIRPA	skin color front paws	0.0 %	1.0
SHIRPA	skin color snout	0.0 %	1.0
SHIRPA	skin color tail	0.0 %	1.0
SHIRPA	skin color whole body	0.0 %	1.0
SHIRPA	skin texture back paw	0.0 %	1.0
SHIRPA	skin texture ear	0.0 %	1.0
SHIRPA	skin texture front paws	0.0 %	1.0
SHIRPA	skin texture snout	0.0 %	1.0
SHIRPA	skin texture tail	0.0 %	1.0
SHIRPA	skin texture whole body	0.0 %	1.00
SHIRPA	snout size	0.0 %	1.0
SHIRPA	startle response	0.0 %	1.00
SHIRPA	tail curvature	0.0 %	1.0
SHIRPA	tail elevation	1.0 %	1.0
SHIRPA	tail length	0.0 %	1.00
SHIRPA	tail morphology	0.0 %	1.00
SHIRPA	tail presence	0.0 %	1.0
SHIRPA	tail shape	0.0 %	1.00
SHIRPA	tail thickness	0.0 %	1.0
SHIRPA	teeth presence	0.0 %	1.00
SHIRPA	transfer arousal	6.0 %	0.109
SHIRPA	tremor	0.0 %	1.00
SHIRPA	trunk curl	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	0.0 %	1.00
SHIRPA	upper lip morphology	0.0 %	1.0
SHIRPA	upper teeth appearance	0.0 %	1.00
SHIRPA	vibrissae appearance	1.0 %	1.0
SHIRPA	vibrissae presence	2.0 %	1.0
SHIRPA	vocalization	2.0 %	1.00

GENOTYPE CORRELATION PLOT

Correlate Cstf1^em1(IMPC)J/Mmjax -/+ with genotype:

This genotype correlation visualization can include both EAP and LAP measures.