MPD: JaxKOMP-EAP genotype: Ankrd24<sup>em1(IMPC)J</sup>/Mmjax -/-

JaxKOMP-EAP effect sizes: Ankrd24^em1(IMPC)J/Mmjax -/- Gene Ankrd24

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

In this plot, data points are the computed genotype effect size vs. C57BL/6NJ controls, for all measured numeric phenotypes in JaxKOMP-EAP

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Plot Options Group by Procedure Standard Error Show Effect Sizes RankZ

Significance Threshold p-Value Threshold Adjusted Unadjusted

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Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value

ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	6.5065	4.3817	1.3981	0.586	0.160
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	30.932	5.7832	2.5698	0.0140	0.000103
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	44.792	5.9432	2.6550	0.000349	0.00000178
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	14.792	2.2204	1.9276	0.00193	0.00000759
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	12.478	4.9788	1.7877	0.235	0.0242
body composition	body length	-0.19201	0.081780	-1.5168	0.171	0.0305
body composition	body weight (at time of DXA)	-2.1458	0.76562	-1.2963	0.0622	0.0114
body composition	bone area, whole body scan, head excluded	0.042379	0.17718	0.36277	0.922	0.814
body composition	bone mineral content of whole body scan, head excluded	-0.013612	0.012600	-0.60742	0.582	0.294
body composition	bone mineral content to body weight ratio	0.000098371	0.00052056	0.29645	0.940	0.852
body composition	bone mineral density of whole body scan, head excluded	-0.0017281	0.00068818	-1.5785	0.146	0.0218
body composition	fat tissue mass of whole body scan, head excluded	0.38851	0.45051	0.62890	0.657	0.400
body composition	fat tissue mass to body weight ratio	0.0067040	0.013272	0.37886	0.798	0.619
body composition	lean tissue mass of whole body scan, head excluded	-0.68862	0.48011	-1.4307	0.470	0.169
body composition	lean tissue mass to body weight ratio	-0.011820	0.011240	-0.70525	0.567	0.307
body composition	percent fat, whole body scan, head excluded	0.74208	1.2157	0.43673	0.750	0.549
body composition	ratio of soft-tissue attenuation coefficients	-0.00076980	0.0013916	-0.40485	0.778	0.587
body composition	tissue area	0.21016	0.34476	0.83929	0.813	0.550
body composition	total tissue mass, whole body scan, head excluded	-0.22938	0.61419	-0.75560	0.849	0.713
clinical blood chemistry	alanine transaminase (plasma ALT)	-1.6968	20.483	-0.18742	0.985	0.942
clinical blood chemistry	albumin (plasma Alb)	0.88024	0.40431	1.3006	0.480	0.161
clinical blood chemistry	alkaline phosphatase (plasma ALP)	0.33644	4.5135	-0.47257	0.971	0.947
clinical blood chemistry	aspartate transaminase (plasma AST)	21.715	54.743	0.83477	0.910	0.730
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	0.58056	0.44974	1.5267	0.727	0.326
clinical blood chemistry	blood urea nitrogen (BUN)	-0.96061	2.9769	-0.42758	0.897	0.778
clinical blood chemistry	calcium (plasma Ca)	0.24896	0.16491	1.8799	0.500	0.270
clinical blood chemistry	creatinine (plasma)	-0.0060687	0.051855	-0.013279	0.956	0.918
clinical blood chemistry	glucose (plasma GLU, no fast)	49.520	16.991	1.9686	0.255	0.100
clinical blood chemistry	HDL cholesterol (plasma HDL)	6.1017	4.4796	1.0520	0.611	0.306
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	-0.022068	0.057949	-1.3183	0.917	0.740
clinical blood chemistry	phosphorus (plasma phosphate)	-1.8552	0.71307	-2.2778	0.361	0.121
clinical blood chemistry	total bilirubin (plasma TBIL)	-0.0054699	0.0075356	-0.43021	0.804	0.543
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	11.586	5.9211	1.5123	0.487	0.190
clinical blood chemistry	total protein (plasma TP)	2.2513	0.73488	1.4840	0.348	0.0921
clinical blood chemistry	triglyceride (plasma TG, no fast)	28.253	16.236	1.5411	0.516	0.224
ERG v2.0	left eye a-wave amplitude (Photopic)	1.3150	1.1215	0.43677	0.692	0.362
ERG v2.0	left eye a-wave amplitude (Scotopic)	79.441	19.582	2.3743	0.365	0.0557
ERG v2.0	left eye a-wave implicit timing (Photopic)	-1.0378	1.8810	-0.36316	0.951	0.637
ERG v2.0	left eye a-wave implicit timing (Scotopic)	3.6592	0.87270	2.2916	0.403	0.0524
ERG v2.0	left eye b-wave amplitude (Photopic)	-33.515	19.291	-2.2916	0.645	0.224
ERG v2.0	left eye b-wave amplitude (Scotopic)	-219.22	34.274	-2.4787	0.278	0.0236
ERG v2.0	left eye b-wave implicit timing (Photopic)	-10.863	8.3764	-2.1073	0.658	0.324
ERG v2.0	left eye b-wave implicit timing (Scotopic)	-14.475	10.424	-1.3006	0.714	0.299
ERG v2.0	left eye c-wave amplitude (Scotopic)	-146.79	29.838	-2.4795	0.379	0.0389
ERG v2.0	left eye c-wave implicit timing (Scotopic)	-130.40	58.329	-1.2766	0.577	0.155
ERG v2.0	left eye FO-like wave amplitude (Scotopic)	121.72	61.811	1.4426	0.588	0.188
ERG v2.0	left eye FO-like wave implicit timing (Scotopic)	407.74	183.16	1.5241	0.666	0.156
ERG v2.0	right eye a-wave amplitude (Photopic)	5.0425	2.7976	1.5998	0.705	0.213
ERG v2.0	right eye a-wave amplitude (Scotopic)	51.492	31.671	1.5614	0.686	0.246
ERG v2.0	right eye a-wave implicit timing (Photopic)	-1.0370	2.5693	-0.50240	0.941	0.726
ERG v2.0	right eye a-wave implicit timing (Scotopic)	0.83725	1.6200	0.68492	0.902	0.657
ERG v2.0	right eye b-wave amplitude (Photopic)	-15.598	10.798	-1.4426	0.673	0.285
ERG v2.0	right eye b-wave amplitude (Scotopic)	-135.63	66.221	-1.7317	0.671	0.177
ERG v2.0	right eye b-wave implicit timing (Photopic)	-0.94444	4.9071	-0.049493	0.955	0.865
ERG v2.0	right eye b-wave implicit timing (Scotopic)	-10.963	8.5314	-1.0787	0.792	0.328
ERG v2.0	right eye c-wave amplitude (Scotopic)	-122.77	65.421	-2.2215	0.595	0.201
ERG v2.0	right eye c-wave implicit timing (Scotopic)	-64.678	104.38	-0.59201	0.858	0.599
ERG v2.0	right eye FO-like wave amplitude (Scotopic)	165.34	94.606	2.0592	0.616	0.223
ERG v2.0	right eye FO-like wave implicit timing (Scotopic)	-212.67	567.57	-0.62026	0.938	0.744
glucose tolerance test	amount glucose injected	2.9312	2.2990	1.1634	0.698	0.330
glucose tolerance test	plasma glucose, 0min	20.495	13.531	1.6359	0.487	0.269
glucose tolerance test	plasma glucose, 15min	126.44	36.807	2.7178	0.324	0.0753
glucose tolerance test	plasma glucose, 30min	91.940	35.498	2.2060	0.439	0.122
glucose tolerance test	plasma glucose, 60min	52.426	50.515	1.9207	0.726	0.408
glucose tolerance test	plasma glucose, 120min	13.813	31.865	0.81301	0.892	0.707
grip strength	body weight (at time of grip strength test)	-1.5688	0.58804	-1.1364	0.0631	0.0152
grip strength	forelimb and hindlimb grip strength (mean of trials), average	-5.2428	8.7563	-0.14427	0.735	0.557
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	-0.17802	0.41038	-0.066854	0.812	0.670
grip strength	forelimb and hindlimb grip strength by trial, trial1	-5.4518	7.7361	-0.13254	0.750	0.490
grip strength	forelimb and hindlimb grip strength by trial, trial2	0.70352	10.549	0.27500	0.980	0.948
grip strength	forelimb and hindlimb grip strength by trial, trial3	-5.0870	14.940	-0.13841	0.888	0.737
grip strength	forelimb grip strength (mean of trials), average	-13.839	4.9729	-1.3862	0.0838	0.0119
grip strength	forelimb grip strength (mean of trials), average normalized to bw	-0.18108	0.26624	-0.23002	0.754	0.505
grip strength	forelimb grip strength by trial, trial1	-7.8378	7.3717	-0.65008	0.648	0.302
grip strength	forelimb grip strength by trial, trial2	-5.1600	7.9518	-0.34974	0.806	0.525
grip strength	forelimb grip strength by trial, trial3	-5.9732	7.8633	-0.41063	0.746	0.457
heart weight	heart weight, normalized to body weight	0.033823	0.16288	-0.32665	0.918	0.838
heart weight	heart weight, weight	-4.6756	4.7852	-0.99845	0.556	0.341
hematology	basophil differential (percent of total WBC)	0.086076	0.031684	1.1808	0.534	0.113
hematology	calculated hemoglobin (cHGB)	-0.016326	0.47825	-0.33652	0.990	0.976
hematology	eosinophil differential (percent of total WBC)	0.47468	0.22526	1.3373	0.563	0.170
hematology	hematocrit (HCT)	0.42077	0.35165	0.084840	0.626	0.354
hematology	hemoglobin concentration distribution width (HDW)	-0.0067323	0.073651	-0.17119	0.966	0.935
hematology	large unstained cells (percent of total WBC)	-0.042025	0.14271	-0.26988	0.908	0.796
hematology	lymphocyte differential (percent of total WBC)	-0.88650	0.62894	-0.41926	0.551	0.294
hematology	mean corpuscular hemoglobin (CHr)	0.064770	0.33076	0.53060	0.932	0.863
hematology	mean platelet volume (MPV)	0.87430	0.35090	2.2558	0.312	0.130
hematology	mean RBC corpuscular hemoglobin (MCH)	0.15956	0.15990	0.59303	0.756	0.423
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	0.19656	0.63910	0.45035	0.933	0.787
hematology	mean RBC corpuscular volume (MCV)	-0.061751	0.53588	-0.11093	0.964	0.919
hematology	measured hemoglobin (mHGB)	0.10219	0.43769	0.011624	0.931	0.837
hematology	monocyte differential (percent of total WBC)	-0.016456	0.12135	0.15506	0.963	0.905
hematology	neutrophil differential (percent of total WBC)	0.69114	1.2726	0.36611	0.809	0.642
hematology	platelet count (PLT; units per volume x 10³)	48.962	93.463	0.70834	0.866	0.653
hematology	RBC corpuscular distribution width (RDW)	-0.058228	0.23601	-0.19795	0.914	0.828
hematology	RBC corpuscular hemoglobin concentration mean (CHCM)	-0.21287	0.77140	-0.61239	0.921	0.808
hematology	red blood cell count (RBC; per volume x 10⁶)	0.10397	0.16418	0.11243	0.785	0.591
hematology	reticulocyte count (Retic; units per volume x 10⁹)	-38.018	18.374	-1.3869	0.566	0.174
hematology	reticulocyte differential (percent of total RBC)	-0.41549	0.19731	-1.4172	0.521	0.170
hematology	white blood cell count (WBC; units per volume x 10³)	3.1439	1.8705	2.0615	0.442	0.235
light / dark	latency to enter dark zone, 20 min test	-46.230	76.497	-0.95882	0.856	0.550
light / dark	number of transitions between light and dark zones, 20 min test	-6.8896	8.5629	-0.59107	0.710	0.426
light / dark	percentage of total time in dark zone, 20 min test	0.81203	6.1657	0.29208	0.966	0.896
light / dark	percentage of total time in light zone, 20 min test	-0.81203	6.1657	-0.29773	0.966	0.896
light / dark	time mobile in dark zone, 20 min test	4.8977	13.201	0.23468	0.884	0.713
light / dark	time mobile in light zone, 20 min test	-11.480	13.527	-1.0390	0.661	0.402
light / dark	time spent in dark zone, 20 min test	99.092	76.108	1.6433	0.633	0.202
light / dark	time spent in light zone, 20 min test	-99.092	76.108	-1.6433	0.633	0.202
open field	average speed in center of arena, 20 min test	-0.57052	0.41156	-1.1724	0.510	0.174
open field	average speed in periphery of arena, 20 min test	0.079979	0.18615	-0.18430	0.819	0.670
open field	distance traveled habituation ratio, 20 min test	-3.7501	6.4652	-0.27253	0.800	0.565
open field	distance traveled in center of arena, 20 min test	58.828	105.30	0.015440	0.765	0.580
open field	distance traveled in periphery of arena, 20 min test	3.4677	193.36	-0.42239	0.995	0.986
open field	distance traveled slope, 20 min test	-5.3887	6.3073	-0.44156	0.696	0.399
open field	distance traveled, 20 min test, 1st 5min	47.167	78.848	0.051713	0.771	0.553
open field	distance traveled, 20 min test, 2nd 5min	61.149	66.999	0.17748	0.608	0.367
open field	distance traveled, 20 min test, 3rd 5min	-2.8354	62.510	-0.47436	0.991	0.964
open field	distance traveled, 20 min test, 4th 5min	2.5812	66.655	-0.43860	0.987	0.969
open field	number of clockwise revolution episodes, 20 min test	3.7516	1.8719	1.4624	0.291	0.0526
open field	number of counter-clockwise revolution episodes, 20 min test	-1.7961	1.2054	-1.4028	0.409	0.145
open field	number of rears in 5 min bins, 20 min test, 1st 5min	0.16272	1.7979	-0.17280	0.965	0.928
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	1.4240	2.3609	-0.0033565	0.771	0.550
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	0.59504	2.7452	-0.18567	0.921	0.830
open field	number of rears in 5 min bins, 20 min test, 4th 5min	-1.5795	2.9323	-0.67913	0.794	0.593
open field	percentage of total time in center of arena, 20 min test	4.7024	3.5379	0.85393	0.504	0.192
open field	percentage of total time in center of arena, slope, 20 min test	1.4589	1.1616	0.93610	0.682	0.217
open field	percentage of total time in center, habituation ratio, 20 min test	1.5335	1.2112	0.94027	0.693	0.214
open field	percentage of total time in corners of arena, 20 min test	-7.1527	4.4066	-1.0435	0.413	0.113
open field	percentage of total time in corners, habituation ratio, 20 min test	0.27740	1.7037	-0.15434	0.980	0.872
open field	percentage of total time in corners, slope, 20 min test	-0.21838	1.7006	-0.36150	0.969	0.899
open field	permanence time in center of arena, 20 min test	56.415	42.455	0.85393	0.504	0.192
open field	permanence time in corners of arena, 20 min test	-85.814	52.880	-1.0435	0.412	0.113
open field	permanence time in periphery of arena, 20 min test	-56.398	42.452	-0.85393	0.503	0.192
open field	total distance traveled, 20 min test	97.382	251.23	-0.20757	0.842	0.701
open field	total number of rears, 20 min test	0.090311	8.1788	-0.33297	0.997	0.991
open field	whole arena average speed, 20 min test	0.082469	0.20943	-0.20346	0.839	0.696
open field	whole arena resting time, 20 min test	-33.578	24.160	-0.37011	0.354	0.173
open field	whole arena time spent mobile, 20 min test	33.590	24.158	0.62597	0.358	0.173
open field	whole arena time spent vertical, 20 min test	-4.8681	7.0611	-0.51994	0.764	0.495
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	-0.30379	2.1294	0.042011	0.972	0.888
startle / PPI	average baseline movement during background noise	0.61732	1.1321	0.48100	0.915	0.589
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	0.20225	0.059989	1.6473	0.0799	0.00188
startle / PPI	average of each corrected percent pre-pulse inhibition value	0.22292	0.059017	2.0394	0.0402	0.000630
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.49872	9.0989	0.11867	0.995	0.957
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	17.202	7.0595	1.7543	0.251	0.0204
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	18.720	5.1137	1.8091	0.0297	0.000846
startle / PPI	average startle response to full pulse (120 dB)	-235.10	35.358	-2.8428	0.0000160	1.25e-7
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-220.32	30.140	-2.9333	0.00000464	1.81e-8
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-190.22	29.213	-2.8428	0.0000306	1.88e-7
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-154.13	25.527	-2.6142	0.000106	7.69e-7
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	2.9836	1.4719	1.5611	0.523	0.0506
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	0.86665	1.3077	0.57112	0.891	0.512
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	0.14055	2.2025	-0.10598	0.989	0.949
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.00061083	0.10475	0.037139	0.998	0.995
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.25189	0.072039	1.9201	0.0674	0.00133
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.36430	0.060627	2.2475	0.000335	8.39e-7
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	-235.05	34.837	-2.8428	0.0000120	9.38e-8
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	-223.31	29.828	-2.8428	0.00000279	1.09e-8
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	-191.09	28.935	-2.8428	0.0000233	1.43e-7
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	-154.03	25.751	-2.5737	0.000110	9.10e-7
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.012965	0.11218	0.14411	0.990	0.909
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.25401	0.076660	1.8089	0.0855	0.00220
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.37549	0.063841	2.0396	0.000461	0.00000123
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	-848.93	124.56	-2.8428	0.0000125	7.67e-8
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	-830.16	106.28	-2.9333	0.00000155	4.32e-9
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	-706.79	106.04	-2.7709	0.0000213	1.19e-7
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	-574.63	95.996	-2.6142	0.0000945	8.98e-7
startle / PPI	maximum baseline movement during background noise	1.6446	2.9562	0.56948	0.887	0.582
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	3.3998	10.083	0.36001	0.961	0.738
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	18.354	7.3316	1.6528	0.217	0.0173
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	21.556	5.9101	1.8620	0.0280	0.000878
startle / PPI	maximum startle response to full pulse (120 dB)	-849.17	125.80	-2.9333	0.0000139	9.30e-8
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-822.96	107.00	-2.9333	0.00000217	6.07e-9
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-706.16	106.41	-2.7110	0.0000241	1.30e-7
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-574.94	95.221	-2.6142	0.0000917	7.69e-7
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	6.7792	4.0670	1.5755	0.582	0.105
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	0.63568	2.6216	0.20959	0.972	0.810
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	0.23682	5.3534	-0.11444	0.994	0.965

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

In this plot, data points are the computed genotype effect % vs. C57BL/6NJ controls, for all measured categorical phenotypes in JaxKOMP-EAP

Dimensions Width: × Height: px

Plot Options Group by Procedure

Include Sexes Data Both Females Males

Significance Threshold p-Value Threshold

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Procedure	JaxKOMP-EAP Trait	Sex	Trait Effect	P-value

eye morphology	anterior chamber depth	females	1.0 %	1.0
eye morphology	anterior chamber depth	males	0.0 %	1.0
eye morphology	anterior chamber depth	both	1.0 %	1.0
eye morphology	bulging eye	females	1.0 %	1.0
eye morphology	bulging eye	males	0.0 %	1.0
eye morphology	bulging eye	both	1.0 %	1.00
eye morphology	cornea	females	13.0 %	0.155
eye morphology	cornea	males	2.0 %	1.0
eye morphology	cornea	both	6.0 %	0.234
eye morphology	cornea opacity	females	26.0 %	0.0701
eye morphology	cornea opacity	males	12.0 %	0.111
eye morphology	cornea opacity	both	18.0 %	0.0296
eye morphology	cornea vascularization	females	28.0 %	0.0106
eye morphology	cornea vascularization	males	1.0 %	1.0
eye morphology	cornea vascularization	both	13.0 %	0.0223
eye morphology	corneal deposits	females	2.0 %	1.0
eye morphology	corneal deposits	males	1.0 %	1.0
eye morphology	corneal deposits	both	1.0 %	1.00
eye morphology	corneal mineralization	females	2.0 %	1.0
eye morphology	corneal mineralization	males	1.0 %	1.0
eye morphology	corneal mineralization	both	1.0 %	1.0
eye morphology	corneal scleralization	females	27.0 %	0.0167
eye morphology	corneal scleralization	males	1.0 %	1.0
eye morphology	corneal scleralization	both	13.0 %	0.0317
eye morphology	corneal ulcer	females	1.0 %	1.0
eye morphology	corneal ulcer	males	1.0 %	1.0
eye morphology	corneal ulcer	both	1.0 %	1.0
eye morphology	eye closure	females	1.0 %	1.0
eye morphology	eye closure	males	0.0 %	1.0
eye morphology	eye closure	both	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	females	14.0 %	0.0611
eye morphology	eye hemorrhage or blood presence	males	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	both	7.0 %	0.0830
eye morphology	eyelid morphology	females	1.0 %	1.0
eye morphology	eyelid morphology	males	0.0 %	1.0
eye morphology	eyelid morphology	both	1.0 %	1.0
eye morphology	eyes (present, absent)	females	1.0 %	1.0
eye morphology	eyes (present, absent)	males	0.0 %	1.0
eye morphology	eyes (present, absent)	both	0.0 %	1.0
eye morphology	fusion between cornea and lens	females	4.0 %	1.0
eye morphology	fusion between cornea and lens	males	2.0 %	1.0
eye morphology	fusion between cornea and lens	both	3.0 %	1.0
eye morphology	iris pigmentation	females	2.0 %	1.0
eye morphology	iris pigmentation	males	1.0 %	1.0
eye morphology	iris pigmentation	both	2.0 %	1.0
eye morphology	iris transillumination	females	2.0 %	1.0
eye morphology	iris transillumination	males	1.0 %	1.0
eye morphology	iris transillumination	both	1.0 %	1.00
eye morphology	irispupil	females	4.0 %	1.0
eye morphology	irispupil	males	3.0 %	1.0
eye morphology	irispupil	both	3.0 %	1.0
eye morphology	lacrimation	females	3.0 %	1.00
eye morphology	lacrimation	males	2.0 %	1.0
eye morphology	lacrimation	both	3.0 %	1.0
eye morphology	lens	females	10.0 %	1.0
eye morphology	lens	males	8.0 %	1.0
eye morphology	lens	both	9.0 %	1.0
eye morphology	lens opacity	females	9.0 %	1.0
eye morphology	lens opacity	males	10.0 %	0.368
eye morphology	lens opacity	both	4.0 %	0.679
eye morphology	narrow eye opening	females	2.0 %	1.00
eye morphology	narrow eye opening	males	1.0 %	1.0
eye morphology	narrow eye opening	both	1.0 %	1.00
eye morphology	optic disc	females	4.0 %	1.0
eye morphology	optic disc	males	2.0 %	1.0
eye morphology	optic disc	both	3.0 %	1.00
eye morphology	persistence of hyaloid vascular system	females	14.0 %	1.0
eye morphology	persistence of hyaloid vascular system	males	11.0 %	0.333
eye morphology	persistence of hyaloid vascular system	both	3.0 %	0.769
eye morphology	pupil dilation	females	2.0 %	1.0
eye morphology	pupil dilation	males	1.0 %	1.0
eye morphology	pupil dilation	both	2.0 %	1.0
eye morphology	pupil light response	females	2.0 %	1.0
eye morphology	pupil light response	males	1.0 %	1.0
eye morphology	pupil light response	both	2.0 %	1.0
eye morphology	pupil position	females	4.0 %	1.0
eye morphology	pupil position	males	3.0 %	1.0
eye morphology	pupil position	both	4.0 %	1.0
eye morphology	pupil shape	females	3.0 %	1.0
eye morphology	pupil shape	males	2.0 %	1.0
eye morphology	pupil shape	both	3.0 %	1.0
eye morphology	retina	females	10.0 %	1.0
eye morphology	retina	males	7.0 %	0.750
eye morphology	retina	both	6.0 %	0.872
eye morphology	retinal blood vessels	females	4.0 %	1.0
eye morphology	retinal blood vessels	males	2.0 %	1.0
eye morphology	retinal blood vessels	both	3.0 %	1.0
eye morphology	retinal blood vessels pattern	females	14.0 %	0.120
eye morphology	retinal blood vessels pattern	males	2.0 %	1.0
eye morphology	retinal blood vessels pattern	both	6.0 %	0.193
eye morphology	retinal blood vessels structure	females	4.0 %	1.0
eye morphology	retinal blood vessels structure	males	2.0 %	1.0
eye morphology	retinal blood vessels structure	both	3.0 %	1.0
eye morphology	retinal pigmentation	females	12.0 %	1.0
eye morphology	retinal pigmentation	males	14.0 %	1.0
eye morphology	retinal pigmentation	both	13.0 %	1.0
eye morphology	retinal structure	females	4.0 %	1.0
eye morphology	retinal structure	males	2.0 %	1.0
eye morphology	retinal structure	both	3.0 %	1.00
eye morphology	synechia	females	4.0 %	1.0
eye morphology	synechia	males	2.0 %	1.0
eye morphology	synechia	both	3.0 %	1.00
eye morphology	vitreous	females	4.0 %	1.0
eye morphology	vitreous	males	2.0 %	1.0
eye morphology	vitreous	both	3.0 %	1.0
SHIRPA	activity body position	females	14.0 %	0.0701
SHIRPA	activity body position	males	12.0 %	0.126
SHIRPA	activity body position	both	13.0 %	0.0100
SHIRPA	aggression	females	14.0 %	0.0355
SHIRPA	aggression	males	12.0 %	0.0522
SHIRPA	aggression	both	13.0 %	0.00338
SHIRPA	body length	females	0.0 %	1.0
SHIRPA	body length	males	0.0 %	1.00
SHIRPA	body length	both	0.0 %	1.0
SHIRPA	body position	females	0.0 %	1.0
SHIRPA	body position	males	1.0 %	1.0
SHIRPA	body position	both	0.0 %	1.00
SHIRPA	body thickness	females	1.0 %	1.0
SHIRPA	body thickness	males	0.0 %	1.0
SHIRPA	body thickness	both	0.0 %	1.00
SHIRPA	coat color abdomen	females	3.0 %	1.0
SHIRPA	coat color abdomen	males	4.0 %	1.0
SHIRPA	coat color abdomen	both	4.0 %	1.00
SHIRPA	coat color back	females	0.0 %	1.0
SHIRPA	coat color back	males	0.0 %	1.00
SHIRPA	coat color back	both	0.0 %	1.00
SHIRPA	coat color head	females	0.0 %	1.0
SHIRPA	coat color head	males	0.0 %	1.00
SHIRPA	coat color head	both	0.0 %	1.0
SHIRPA	coat color pattern abdomen	females	1.0 %	1.0
SHIRPA	coat color pattern abdomen	males	1.0 %	1.0
SHIRPA	coat color pattern abdomen	both	1.0 %	1.00
SHIRPA	coat color pattern back	females	0.0 %	1.0
SHIRPA	coat color pattern back	males	0.0 %	1.00
SHIRPA	coat color pattern back	both	0.0 %	1.00
SHIRPA	coat color pattern head	females	0.0 %	1.0
SHIRPA	coat color pattern head	males	0.0 %	1.0
SHIRPA	coat color pattern head	both	0.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	females	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	males	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	both	2.0 %	1.0
SHIRPA	coat hair back texture appearance	females	0.0 %	1.0
SHIRPA	coat hair back texture appearance	males	0.0 %	1.0
SHIRPA	coat hair back texture appearance	both	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	females	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	males	1.0 %	1.00
SHIRPA	coat hair distribution abdomen	both	1.0 %	1.0
SHIRPA	coat hair distribution back	females	0.0 %	1.0
SHIRPA	coat hair distribution back	males	0.0 %	1.0
SHIRPA	coat hair distribution back	both	0.0 %	1.00
SHIRPA	coat hair distribution head	females	1.0 %	1.00
SHIRPA	coat hair distribution head	males	1.0 %	1.0
SHIRPA	coat hair distribution head	both	1.0 %	1.0
SHIRPA	coat hair head texture appearance	females	0.0 %	1.0
SHIRPA	coat hair head texture appearance	males	0.0 %	1.0
SHIRPA	coat hair head texture appearance	both	0.0 %	1.0
SHIRPA	contact righting	females	5.0 %	1.0
SHIRPA	contact righting	males	5.0 %	1.00
SHIRPA	contact righting	both	5.0 %	1.00
SHIRPA	ear morphology	females	0.0 %	1.0
SHIRPA	ear morphology	males	0.0 %	1.0
SHIRPA	ear morphology	both	0.0 %	1.0
SHIRPA	fat distribution	females	0.0 %	1.0
SHIRPA	fat distribution	males	0.0 %	1.0
SHIRPA	fat distribution	both	0.0 %	1.0
SHIRPA	forelimb digit number	females	0.0 %	1.0
SHIRPA	forelimb digit number	males	0.0 %	1.0
SHIRPA	forelimb digit number	both	0.0 %	1.0
SHIRPA	forelimb digit position	females	0.0 %	1.0
SHIRPA	forelimb digit position	males	0.0 %	1.0
SHIRPA	forelimb digit position	both	0.0 %	1.0
SHIRPA	forelimb digit shape	females	0.0 %	1.0
SHIRPA	forelimb digit shape	males	0.0 %	1.0
SHIRPA	forelimb digit shape	both	0.0 %	1.0
SHIRPA	forelimb digit size	females	0.0 %	1.0
SHIRPA	forelimb digit size	males	0.0 %	1.0
SHIRPA	forelimb digit size	both	0.0 %	1.0
SHIRPA	forelimb footpads	females	0.0 %	1.0
SHIRPA	forelimb footpads	males	0.0 %	1.0
SHIRPA	forelimb footpads	both	0.0 %	1.0
SHIRPA	forelimb nail length	females	0.0 %	1.0
SHIRPA	forelimb nail length	males	0.0 %	1.0
SHIRPA	forelimb nail length	both	0.0 %	1.0
SHIRPA	forelimb nail number	females	0.0 %	1.0
SHIRPA	forelimb nail number	males	0.0 %	1.0
SHIRPA	forelimb nail number	both	0.0 %	1.0
SHIRPA	forelimb nail position	females	0.0 %	1.0
SHIRPA	forelimb nail position	males	0.0 %	1.0
SHIRPA	forelimb nail position	both	0.0 %	1.0
SHIRPA	forelimb nail shape	females	0.0 %	1.0
SHIRPA	forelimb nail shape	males	0.0 %	1.0
SHIRPA	forelimb nail shape	both	0.0 %	1.0
SHIRPA	forelimbs position	females	0.0 %	1.0
SHIRPA	forelimbs position	males	0.0 %	1.0
SHIRPA	forelimbs position	both	0.0 %	1.0
SHIRPA	forelimbs shape	females	0.0 %	1.0
SHIRPA	forelimbs shape	males	0.0 %	1.0
SHIRPA	forelimbs shape	both	0.0 %	1.0
SHIRPA	forelimbs size	females	0.0 %	1.0
SHIRPA	forelimbs size	males	0.0 %	1.0
SHIRPA	forelimbs size	both	0.0 %	1.0
SHIRPA	forepaw position	females	0.0 %	1.0
SHIRPA	forepaw position	males	0.0 %	1.0
SHIRPA	forepaw position	both	0.0 %	1.0
SHIRPA	forepaw shape	females	0.0 %	1.0
SHIRPA	forepaw shape	males	0.0 %	1.0
SHIRPA	forepaw shape	both	0.0 %	1.0
SHIRPA	forepaw size	females	0.0 %	1.0
SHIRPA	forepaw size	males	0.0 %	1.0
SHIRPA	forepaw size	both	0.0 %	1.0
SHIRPA	gait (fluidity)	females	0.0 %	1.0
SHIRPA	gait (fluidity)	males	0.0 %	1.00
SHIRPA	gait (fluidity)	both	0.0 %	1.0
SHIRPA	genitalia morphology	females	0.0 %	1.0
SHIRPA	genitalia morphology	males	0.0 %	1.0
SHIRPA	genitalia morphology	both	0.0 %	1.00
SHIRPA	genitalia presence	females	0.0 %	1.0
SHIRPA	genitalia presence	males	0.0 %	1.0
SHIRPA	genitalia presence	both	0.0 %	1.0
SHIRPA	genitalia size	females	0.0 %	1.0
SHIRPA	genitalia size	males	0.0 %	1.0
SHIRPA	genitalia size	both	0.0 %	1.00
SHIRPA	head bobbing	females	0.0 %	1.0
SHIRPA	head bobbing	males	0.0 %	1.0
SHIRPA	head bobbing	both	0.0 %	1.0
SHIRPA	head morphology	females	0.0 %	1.0
SHIRPA	head morphology	males	0.0 %	1.00
SHIRPA	head morphology	both	0.0 %	1.0
SHIRPA	head size	females	0.0 %	1.0
SHIRPA	head size	males	0.0 %	1.0
SHIRPA	head size	both	0.0 %	1.0
SHIRPA	hindlimb digit number	females	1.0 %	1.0
SHIRPA	hindlimb digit number	males	0.0 %	1.0
SHIRPA	hindlimb digit number	both	0.0 %	1.0
SHIRPA	hindlimb digit position	females	0.0 %	1.0
SHIRPA	hindlimb digit position	males	0.0 %	1.0
SHIRPA	hindlimb digit position	both	0.0 %	1.0
SHIRPA	hindlimb digit shape	females	0.0 %	1.0
SHIRPA	hindlimb digit shape	males	0.0 %	1.0
SHIRPA	hindlimb digit shape	both	0.0 %	1.00
SHIRPA	hindlimb digit size	females	0.0 %	1.0
SHIRPA	hindlimb digit size	males	0.0 %	1.0
SHIRPA	hindlimb digit size	both	0.0 %	1.00
SHIRPA	hindlimb nail length	females	0.0 %	1.0
SHIRPA	hindlimb nail length	males	0.0 %	1.0
SHIRPA	hindlimb nail length	both	0.0 %	1.0
SHIRPA	hindlimb nail number	females	0.0 %	1.0
SHIRPA	hindlimb nail number	males	1.0 %	1.0
SHIRPA	hindlimb nail number	both	0.0 %	1.0
SHIRPA	hindlimb nail position	females	0.0 %	1.0
SHIRPA	hindlimb nail position	males	0.0 %	1.0
SHIRPA	hindlimb nail position	both	0.0 %	1.0
SHIRPA	hindlimb nail shape	females	0.0 %	1.0
SHIRPA	hindlimb nail shape	males	0.0 %	1.0
SHIRPA	hindlimb nail shape	both	0.0 %	1.0
SHIRPA	hindlimbs footpads	females	0.0 %	1.0
SHIRPA	hindlimbs footpads	males	0.0 %	1.0
SHIRPA	hindlimbs footpads	both	0.0 %	1.0
SHIRPA	hindlimbs position	females	0.0 %	1.0
SHIRPA	hindlimbs position	males	0.0 %	1.0
SHIRPA	hindlimbs position	both	0.0 %	1.0
SHIRPA	hindlimbs shape	females	0.0 %	1.0
SHIRPA	hindlimbs shape	males	0.0 %	1.0
SHIRPA	hindlimbs shape	both	0.0 %	1.0
SHIRPA	hindlimbs size	females	0.0 %	1.0
SHIRPA	hindlimbs size	males	0.0 %	1.0
SHIRPA	hindlimbs size	both	0.0 %	1.0
SHIRPA	hindpaw position	females	0.0 %	1.0
SHIRPA	hindpaw position	males	0.0 %	1.0
SHIRPA	hindpaw position	both	0.0 %	1.0
SHIRPA	hindpaw shape	females	0.0 %	1.0
SHIRPA	hindpaw shape	males	0.0 %	1.0
SHIRPA	hindpaw shape	both	0.0 %	1.0
SHIRPA	hindpaw size	females	0.0 %	1.0
SHIRPA	hindpaw size	males	0.0 %	1.0
SHIRPA	hindpaw size	both	0.0 %	1.0
SHIRPA	limb grasp	females	5.0 %	0.478
SHIRPA	limb grasp	males	32.0 %	0.00854
SHIRPA	limb grasp	both	19.0 %	0.0202
SHIRPA	lower lip morphology	females	0.0 %	1.0
SHIRPA	lower lip morphology	males	0.0 %	1.0
SHIRPA	lower lip morphology	both	0.0 %	1.0
SHIRPA	lower teeth appearance	females	0.0 %	1.0
SHIRPA	lower teeth appearance	males	0.0 %	1.00
SHIRPA	lower teeth appearance	both	0.0 %	1.0
SHIRPA	mouth morphology	females	0.0 %	1.0
SHIRPA	mouth morphology	males	0.0 %	1.00
SHIRPA	mouth morphology	both	0.0 %	1.0
SHIRPA	salivation	females	0.0 %	1.0
SHIRPA	salivation	males	0.0 %	1.0
SHIRPA	salivation	both	0.0 %	1.0
SHIRPA	skin color back paws	females	0.0 %	1.0
SHIRPA	skin color back paws	males	0.0 %	1.0
SHIRPA	skin color back paws	both	0.0 %	1.0
SHIRPA	skin color ear	females	0.0 %	1.0
SHIRPA	skin color ear	males	0.0 %	1.0
SHIRPA	skin color ear	both	0.0 %	1.0
SHIRPA	skin color front paws	females	0.0 %	1.0
SHIRPA	skin color front paws	males	0.0 %	1.0
SHIRPA	skin color front paws	both	0.0 %	1.0
SHIRPA	skin color snout	females	0.0 %	1.0
SHIRPA	skin color snout	males	0.0 %	1.0
SHIRPA	skin color snout	both	0.0 %	1.0
SHIRPA	skin color tail	females	0.0 %	1.0
SHIRPA	skin color tail	males	0.0 %	1.0
SHIRPA	skin color tail	both	0.0 %	1.0
SHIRPA	skin color whole body	females	0.0 %	1.0
SHIRPA	skin color whole body	males	0.0 %	1.0
SHIRPA	skin color whole body	both	0.0 %	1.0
SHIRPA	skin texture back paw	females	0.0 %	1.0
SHIRPA	skin texture back paw	males	0.0 %	1.0
SHIRPA	skin texture back paw	both	0.0 %	1.0
SHIRPA	skin texture ear	females	0.0 %	1.0
SHIRPA	skin texture ear	males	0.0 %	1.0
SHIRPA	skin texture ear	both	0.0 %	1.0
SHIRPA	skin texture front paws	females	0.0 %	1.0
SHIRPA	skin texture front paws	males	0.0 %	1.0
SHIRPA	skin texture front paws	both	0.0 %	1.0
SHIRPA	skin texture snout	females	0.0 %	1.0
SHIRPA	skin texture snout	males	0.0 %	1.0
SHIRPA	skin texture snout	both	0.0 %	1.0
SHIRPA	skin texture tail	females	0.0 %	1.0
SHIRPA	skin texture tail	males	0.0 %	1.0
SHIRPA	skin texture tail	both	0.0 %	1.0
SHIRPA	skin texture whole body	females	0.0 %	1.0
SHIRPA	skin texture whole body	males	0.0 %	1.00
SHIRPA	skin texture whole body	both	0.0 %	1.00
SHIRPA	snout size	females	0.0 %	1.0
SHIRPA	snout size	males	1.0 %	1.0
SHIRPA	snout size	both	0.0 %	1.0
SHIRPA	startle response	females	0.0 %	1.0
SHIRPA	startle response	males	0.0 %	1.00
SHIRPA	startle response	both	0.0 %	1.0
SHIRPA	tail curvature	females	0.0 %	1.00
SHIRPA	tail curvature	males	0.0 %	1.0
SHIRPA	tail curvature	both	0.0 %	1.00
SHIRPA	tail elevation	females	1.0 %	1.0
SHIRPA	tail elevation	males	2.0 %	1.0
SHIRPA	tail elevation	both	1.0 %	1.0
SHIRPA	tail length	females	0.0 %	1.0
SHIRPA	tail length	males	0.0 %	1.0
SHIRPA	tail length	both	0.0 %	1.0
SHIRPA	tail morphology	females	0.0 %	1.0
SHIRPA	tail morphology	males	0.0 %	1.0
SHIRPA	tail morphology	both	0.0 %	1.00
SHIRPA	tail presence	females	0.0 %	1.0
SHIRPA	tail presence	males	0.0 %	1.0
SHIRPA	tail presence	both	0.0 %	1.0
SHIRPA	tail shape	females	0.0 %	1.0
SHIRPA	tail shape	males	0.0 %	1.0
SHIRPA	tail shape	both	0.0 %	1.0
SHIRPA	tail thickness	females	0.0 %	1.0
SHIRPA	tail thickness	males	0.0 %	1.0
SHIRPA	tail thickness	both	0.0 %	1.0
SHIRPA	teeth presence	females	0.0 %	1.0
SHIRPA	teeth presence	males	0.0 %	1.00
SHIRPA	teeth presence	both	0.0 %	1.0
SHIRPA	transfer arousal	females	14.0 %	0.0771
SHIRPA	transfer arousal	males	12.0 %	0.128
SHIRPA	transfer arousal	both	13.0 %	0.00973
SHIRPA	tremor	females	0.0 %	1.0
SHIRPA	tremor	males	0.0 %	1.0
SHIRPA	tremor	both	0.0 %	1.00
SHIRPA	trunk curl	females	0.0 %	1.0
SHIRPA	trunk curl	males	0.0 %	1.0
SHIRPA	trunk curl	both	0.0 %	1.00
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	females	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	males	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	both	0.0 %	1.0
SHIRPA	upper lip morphology	females	0.0 %	1.0
SHIRPA	upper lip morphology	males	0.0 %	1.0
SHIRPA	upper lip morphology	both	0.0 %	1.0
SHIRPA	upper teeth appearance	females	0.0 %	1.0
SHIRPA	upper teeth appearance	males	0.0 %	1.0
SHIRPA	upper teeth appearance	both	0.0 %	1.0
SHIRPA	vibrissae appearance	females	2.0 %	1.0
SHIRPA	vibrissae appearance	males	1.0 %	1.0
SHIRPA	vibrissae appearance	both	1.0 %	1.0
SHIRPA	vibrissae presence	females	2.0 %	1.00
SHIRPA	vibrissae presence	males	1.0 %	1.0
SHIRPA	vibrissae presence	both	2.0 %	1.0
SHIRPA	vocalization	females	2.0 %	1.00
SHIRPA	vocalization	males	2.0 %	1.0
SHIRPA	vocalization	both	2.0 %	1.0

GENOTYPE CORRELATION PLOT

Correlate Ankrd24^em1(IMPC)J/Mmjax -/- with genotype:

This genotype correlation visualization can include both EAP and LAP measures.