MPD: JaxKOMP-EAP genotype: Kansl3<sup>em1(IMPC)J</sup>/Mmjax -/+

JaxKOMP-EAP effect sizes: Kansl3^em1(IMPC)J/Mmjax -/+ Gene Kansl3

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	1.25	2.7951	0.10826	0.902	0.665
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	-1.7222	4.1291	-0.35973	0.908	0.688
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	6.5005	5.6389	0.97920	0.636	0.282
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	7.3289	6.2335	1.0563	0.655	0.274
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	4.5816	3.5416	0.69220	0.628	0.232
body composition	body length	0.018166	0.068583	0.45243	0.913	0.794
body composition	body weight (at time of DXA)	0.30293	0.88658	0.34441	0.864	0.736
body composition	bone area, whole body scan, head excluded	0.080610	0.22418	0.53351	0.877	0.723
body composition	bone mineral content of whole body scan, head excluded	0.012211	0.018614	0.85178	0.753	0.519
body composition	bone mineral content to body weight ratio	0.00044168	0.00052495	0.78128	0.661	0.410
body composition	bone mineral density of whole body scan, head excluded	0.00060276	0.0010314	0.69826	0.783	0.565
body composition	fat tissue mass of whole body scan, head excluded	-0.060725	0.44877	-0.10395	0.958	0.894
body composition	fat tissue mass to body weight ratio	-0.0049463	0.016084	-0.16319	0.886	0.762
body composition	lean tissue mass of whole body scan, head excluded	0.16151	0.61956	0.18259	0.919	0.797
body composition	lean tissue mass to body weight ratio	0.0030266	0.014971	0.10332	0.922	0.842
body composition	percent fat, whole body scan, head excluded	-0.49018	1.5468	-0.17565	0.887	0.755
body composition	ratio of soft-tissue attenuation coefficients	0.00052072	0.0017182	0.16771	0.896	0.765
body composition	tissue area	0.049969	0.31288	0.36027	0.961	0.875
body composition	total tissue mass, whole body scan, head excluded	0.10079	0.44219	0.0081917	0.915	0.822
clinical blood chemistry	alanine transaminase (plasma ALT)	-3.4795	5.8093	-0.33864	0.839	0.556
clinical blood chemistry	albumin (plasma Alb)	0.19928	0.40131	0.33104	0.855	0.625
clinical blood chemistry	alkaline phosphatase (plasma ALP)	11.511	3.1407	1.3008	0.0225	0.00165
clinical blood chemistry	aspartate transaminase (plasma AST)	-1.3467	6.0207	-0.059582	0.947	0.825
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	0.10649	0.12968	0.37632	0.793	0.421
clinical blood chemistry	blood urea nitrogen (BUN)	-1.5171	1.3885	-0.65350	0.556	0.288
clinical blood chemistry	calcium (plasma Ca)	-0.082073	0.077817	-0.24045	0.540	0.305
clinical blood chemistry	creatinine (plasma)	-0.067105	0.017619	-1.2755	0.0232	0.00129
clinical blood chemistry	glucose (plasma GLU, no fast)	-2.0699	15.178	0.22689	0.938	0.893
clinical blood chemistry	HDL cholesterol (plasma HDL)	10.185	2.6573	1.8570	0.0257	0.00104
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	-0.018245	0.011037	-1.1024	0.422	0.115
clinical blood chemistry	phosphorus (plasma phosphate)	-1.7742	0.66532	-2.2074	0.115	0.0148
clinical blood chemistry	total bilirubin (plasma TBIL)	0.00071160	0.0058654	0.062493	0.971	0.905
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	15.046	3.9419	1.9705	0.0268	0.00108
clinical blood chemistry	total protein (plasma TP)	0.65291	0.50386	0.43595	0.493	0.210
clinical blood chemistry	triglyceride (plasma TG, no fast)	-1.1307	10.340	0.15948	0.963	0.914
glucose tolerance test	amount glucose injected	-0.44191	1.8075	0.22956	0.938	0.810
glucose tolerance test	plasma glucose, 0min	-4.1011	6.1452	-0.62949	0.720	0.514
glucose tolerance test	plasma glucose, 15min	31.680	24.127	1.0039	0.533	0.208
glucose tolerance test	plasma glucose, 30min	3.7010	23.612	0.24542	0.957	0.877
glucose tolerance test	plasma glucose, 60min	-12.974	16.852	-0.42872	0.750	0.452
glucose tolerance test	plasma glucose, 120min	-11.574	12.498	-0.91053	0.653	0.367
heart weight	heart weight, normalized to body weight	0.13173	0.13337	0.031760	0.552	0.335
heart weight	heart weight, weight	2.0524	3.5326	-0.11579	0.737	0.568
hematology	basophil differential (percent of total WBC)	0.010912	0.031581	0.20458	0.928	0.733
hematology	calculated hemoglobin (cHGB)	0.80623	0.28882	1.9151	0.102	0.0104
hematology	eosinophil differential (percent of total WBC)	-0.14843	0.31406	-0.33360	0.885	0.641
hematology	hematocrit (HCT)	2.1009	0.84411	1.7101	0.153	0.0205
hematology	hemoglobin concentration distribution width (HDW)	0.014853	0.017835	0.40355	0.705	0.414
hematology	large unstained cells (percent of total WBC)	-0.066452	0.063029	-0.44795	0.641	0.303
hematology	lymphocyte differential (percent of total WBC)	-0.29484	1.3820	-0.17030	0.926	0.833
hematology	mean corpuscular hemoglobin (CHr)	-0.11821	0.047056	-0.94162	0.0924	0.0198
hematology	mean platelet volume (MPV)	-0.15864	0.12626	-1.0676	0.439	0.222
hematology	mean RBC corpuscular hemoglobin (MCH)	-0.17147	0.13704	-0.65224	0.575	0.223
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	0.20352	0.41185	0.47168	0.854	0.626
hematology	mean RBC corpuscular volume (MCV)	-0.92061	0.29042	-1.3968	0.0310	0.00427
hematology	measured hemoglobin (mHGB)	0.69429	0.28999	1.4977	0.195	0.0252
hematology	monocyte differential (percent of total WBC)	0.32762	0.20999	1.2029	0.487	0.132
hematology	neutrophil differential (percent of total WBC)	0.28450	1.0816	0.16337	0.892	0.795
hematology	platelet count (PLT; units per volume x 10³)	16.784	65.073	0.26409	0.926	0.799
hematology	RBC corpuscular distribution width (RDW)	0.17037	0.089155	0.58304	0.265	0.0691
hematology	RBC corpuscular hemoglobin concentration mean (CHCM)	0.39715	0.22990	0.97579	0.293	0.0981
hematology	red blood cell count (RBC; per volume x 10⁶)	0.65158	0.21681	2.0966	0.0746	0.00631
hematology	reticulocyte count (Retic; units per volume x 10⁹)	3.8550	16.931	0.27468	0.946	0.822
hematology	reticulocyte differential (percent of total RBC)	-0.23715	0.12126	-0.80383	0.366	0.0628
hematology	white blood cell count (WBC; units per volume x 10³)	-0.14831	0.75356	0.075242	0.916	0.846
light / dark	latency to enter dark zone, 20 min test	-47.304	34.787	-0.98484	0.615	0.184
light / dark	number of transitions between light and dark zones, 20 min test	-9.0014	10.913	-0.81457	0.706	0.416
light / dark	percentage of total time in dark zone, 20 min test	3.2734	3.7018	0.70623	0.705	0.384
light / dark	percentage of total time in light zone, 20 min test	-3.2734	3.7018	-0.70797	0.704	0.384
light / dark	time mobile in dark zone, 20 min test	18.441	13.509	0.90457	0.474	0.182
light / dark	time mobile in light zone, 20 min test	-5.8080	13.526	-0.68215	0.836	0.671
light / dark	time spent in dark zone, 20 min test	71.371	49.552	1.2983	0.588	0.160
light / dark	time spent in light zone, 20 min test	-71.371	49.552	-1.2983	0.588	0.160
open field	average speed in center of arena, 20 min test	-0.12102	0.32432	-0.32306	0.895	0.712
open field	average speed in periphery of arena, 20 min test	-0.015472	0.14802	-0.58405	0.953	0.917
open field	distance traveled habituation ratio, 20 min test	5.4492	8.6575	0.47286	0.779	0.534
open field	distance traveled in center of arena, 20 min test	-57.741	120.94	-0.74665	0.796	0.637
open field	distance traveled in periphery of arena, 20 min test	59.749	125.59	-0.18840	0.806	0.638
open field	distance traveled slope, 20 min test	3.3778	8.4613	0.36436	0.885	0.692
open field	distance traveled, 20 min test, 1st 5min	-33.478	69.583	-0.64239	0.831	0.634
open field	distance traveled, 20 min test, 2nd 5min	47.801	43.071	0.034243	0.513	0.276
open field	distance traveled, 20 min test, 3rd 5min	-9.4963	50.668	-0.55249	0.940	0.853
open field	distance traveled, 20 min test, 4th 5min	-3.0543	71.478	-0.49854	0.985	0.966
open field	number of clockwise revolution episodes, 20 min test	-0.99275	1.1592	-1.0362	0.739	0.399
open field	number of counter-clockwise revolution episodes, 20 min test	-0.032203	1.2411	-0.45641	0.991	0.979
open field	number of rears in 5 min bins, 20 min test, 1st 5min	-4.6779	2.1715	-1.4664	0.191	0.0391
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	1.2324	3.1928	-0.057091	0.855	0.702
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	1.1859	3.0946	-0.038273	0.853	0.704
open field	number of rears in 5 min bins, 20 min test, 4th 5min	3.4823	3.3092	0.42533	0.577	0.301
open field	percentage of total time in center of arena, 20 min test	-3.0690	3.3697	-0.95711	0.682	0.370
open field	percentage of total time in center of arena, slope, 20 min test	1.0099	1.2465	0.70472	0.830	0.424
open field	percentage of total time in center, habituation ratio, 20 min test	1.0773	1.1569	0.70472	0.800	0.359
open field	percentage of total time in corners of arena, 20 min test	-2.4606	4.7732	-0.13805	0.836	0.610
open field	percentage of total time in corners, habituation ratio, 20 min test	-3.2442	1.9913	-1.7871	0.590	0.114
open field	percentage of total time in corners, slope, 20 min test	-3.0266	1.9503	-1.7364	0.629	0.131
open field	permanence time in center of arena, 20 min test	-36.817	40.432	-0.95711	0.682	0.370
open field	permanence time in corners of arena, 20 min test	-29.533	57.281	-0.13805	0.836	0.610
open field	permanence time in periphery of arena, 20 min test	36.863	40.438	0.95711	0.682	0.369
open field	total distance traveled, 20 min test	6.3814	188.45	-0.48944	0.987	0.973
open field	total number of rears, 20 min test	1.4235	9.8129	-0.23095	0.947	0.886
open field	whole arena average speed, 20 min test	0.0048778	0.15700	-0.49398	0.986	0.975
open field	whole arena resting time, 20 min test	-5.0418	19.879	0.43712	0.884	0.802
open field	whole arena time spent mobile, 20 min test	5.0826	19.877	-0.31317	0.888	0.800
open field	whole arena time spent vertical, 20 min test	-6.8077	8.5794	-0.67407	0.722	0.434
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	0.39877	1.9835	0.37321	0.957	0.843
startle / PPI	average baseline movement during background noise	-1.0238	1.8843	-0.71597	0.915	0.591
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	0.042577	0.051011	0.29935	0.740	0.410
startle / PPI	average of each corrected percent pre-pulse inhibition value	0.040965	0.046338	0.32769	0.715	0.383
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	5.1944	6.9499	0.61456	0.887	0.460
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.61575	6.1539	-0.10739	0.977	0.921
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	2.1390	5.0730	0.12714	0.878	0.676
startle / PPI	average startle response to full pulse (120 dB)	-73.557	43.491	-1.0690	0.284	0.101
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-87.000	38.459	-1.2170	0.129	0.0308
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-61.283	34.881	-0.95225	0.253	0.0888
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-48.157	32.170	-0.88598	0.341	0.145
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	1.6989	1.7682	1.0159	0.813	0.344
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	1.8345	1.6102	0.97679	0.779	0.263
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	2.5445	2.0314	0.91116	0.664	0.220
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.064909	0.069968	0.64359	0.870	0.361
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.0050801	0.061036	-0.044199	0.981	0.934
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.052905	0.055512	0.26088	0.610	0.348
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	-73.049	43.723	-1.0715	0.288	0.105
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	-88.698	38.925	-1.2319	0.125	0.0297
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	-63.117	34.628	-0.99271	0.233	0.0780
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	-50.702	32.358	-0.92182	0.308	0.127
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.063709	0.078435	0.58603	0.887	0.423
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.00089992	0.064809	-0.085621	0.993	0.989
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.063122	0.061762	0.28708	0.580	0.315
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	-258.82	160.93	-1.0445	0.309	0.118
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	-293.66	141.96	-1.1575	0.165	0.0470
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	-202.50	128.48	-0.86338	0.316	0.125
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	-188.86	120.49	-0.93042	0.308	0.127
startle / PPI	maximum baseline movement during background noise	-3.1612	6.6748	-0.86542	0.919	0.639
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	4.9994	7.8419	0.53036	0.923	0.528
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.92157	6.6792	-0.16965	0.964	0.891
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	3.7227	5.8079	0.19958	0.780	0.526
startle / PPI	maximum startle response to full pulse (120 dB)	-261.24	160.13	-1.0518	0.301	0.113
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-288.46	141.07	-1.1359	0.172	0.0494
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-197.63	129.34	-0.83923	0.331	0.137
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-181.57	119.97	-0.90904	0.336	0.140
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	5.1963	4.2599	1.3104	0.727	0.232
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	4.8714	3.9721	1.1520	0.722	0.229
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	7.2889	4.8777	0.98586	0.516	0.145

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Sex	Trait Effect	P-value
eye morphology	anterior chamber depth	females	12.0 %	0.0556
eye morphology	anterior chamber depth	males	0.0 %	1.0
eye morphology	anterior chamber depth	both	6.0 %	0.0573
eye morphology	bulging eye	females	12.0 %	0.0359
eye morphology	bulging eye	males	0.0 %	1.0
eye morphology	bulging eye	both	7.0 %	0.0383
eye morphology	cornea	females	12.0 %	0.0773
eye morphology	cornea	males	2.0 %	1.0
eye morphology	cornea	both	6.0 %	0.101
eye morphology	cornea opacity	females	12.0 %	0.0333
eye morphology	cornea opacity	males	1.0 %	1.0
eye morphology	cornea opacity	both	7.0 %	0.0449
eye morphology	cornea vascularization	females	12.0 %	0.0161
eye morphology	cornea vascularization	males	1.0 %	1.0
eye morphology	cornea vascularization	both	7.0 %	0.0243
eye morphology	corneal deposits	females	12.0 %	0.0944
eye morphology	corneal deposits	males	1.0 %	1.0
eye morphology	corneal deposits	both	6.0 %	0.0988
eye morphology	corneal mineralization	females	12.0 %	0.103
eye morphology	corneal mineralization	males	1.0 %	1.0
eye morphology	corneal mineralization	both	6.0 %	0.0568
eye morphology	corneal scleralization	females	12.0 %	0.0300
eye morphology	corneal scleralization	males	1.0 %	1.0
eye morphology	corneal scleralization	both	7.0 %	0.0290
eye morphology	corneal ulcer	females	12.0 %	0.0595
eye morphology	corneal ulcer	males	1.0 %	1.0
eye morphology	corneal ulcer	both	7.0 %	0.0692
eye morphology	eye closure	females	12.0 %	0.0358
eye morphology	eye closure	males	0.0 %	1.0
eye morphology	eye closure	both	7.0 %	0.0381
eye morphology	eye hemorrhage or blood presence	females	12.0 %	0.0696
eye morphology	eye hemorrhage or blood presence	males	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	both	6.0 %	0.0830
eye morphology	eyelid morphology	females	12.0 %	0.0443
eye morphology	eyelid morphology	males	0.0 %	1.0
eye morphology	eyelid morphology	both	7.0 %	0.0462
eye morphology	eyes (present, absent)	females	12.0 %	0.0433
eye morphology	eyes (present, absent)	males	0.0 %	1.0
eye morphology	eyes (present, absent)	both	6.0 %	0.0463
eye morphology	fusion between cornea and lens	females	11.0 %	0.144
eye morphology	fusion between cornea and lens	males	2.0 %	1.0
eye morphology	fusion between cornea and lens	both	6.0 %	0.167
eye morphology	iris pigmentation	females	12.0 %	0.166
eye morphology	iris pigmentation	males	1.0 %	1.0
eye morphology	iris pigmentation	both	6.0 %	0.134
eye morphology	iris transillumination	females	12.0 %	0.146
eye morphology	iris transillumination	males	1.0 %	1.00
eye morphology	iris transillumination	both	6.0 %	0.109
eye morphology	irispupil	females	12.0 %	0.193
eye morphology	irispupil	males	3.0 %	1.0
eye morphology	irispupil	both	6.0 %	0.158
eye morphology	lacrimation	females	11.0 %	0.244
eye morphology	lacrimation	males	2.0 %	1.0
eye morphology	lacrimation	both	6.0 %	0.234
eye morphology	lens	females	11.0 %	0.276
eye morphology	lens	males	8.0 %	1.00
eye morphology	lens	both	6.0 %	0.339
eye morphology	lens opacity	females	11.0 %	0.251
eye morphology	lens opacity	males	12.0 %	0.331
eye morphology	lens opacity	both	6.0 %	0.195
eye morphology	narrow eye opening	females	12.0 %	0.0210
eye morphology	narrow eye opening	males	1.0 %	1.0
eye morphology	narrow eye opening	both	7.0 %	0.0203
eye morphology	optic disc	females	11.0 %	0.180
eye morphology	optic disc	males	2.0 %	1.00
eye morphology	optic disc	both	6.0 %	0.227
eye morphology	persistence of hyaloid vascular system	females	11.0 %	0.196
eye morphology	persistence of hyaloid vascular system	males	5.0 %	1.0
eye morphology	persistence of hyaloid vascular system	both	6.0 %	0.285
eye morphology	pupil dilation	females	12.0 %	0.171
eye morphology	pupil dilation	males	1.0 %	1.00
eye morphology	pupil dilation	both	6.0 %	0.153
eye morphology	pupil light response	females	11.0 %	0.179
eye morphology	pupil light response	males	1.0 %	1.0
eye morphology	pupil light response	both	6.0 %	0.223
eye morphology	pupil position	females	12.0 %	0.213
eye morphology	pupil position	males	3.0 %	1.0
eye morphology	pupil position	both	6.0 %	0.172
eye morphology	pupil shape	females	12.0 %	0.176
eye morphology	pupil shape	males	2.0 %	1.0
eye morphology	pupil shape	both	6.0 %	0.174
eye morphology	retina	females	11.0 %	0.288
eye morphology	retina	males	8.0 %	0.703
eye morphology	retina	both	6.0 %	0.298
eye morphology	retinal blood vessels	females	11.0 %	0.154
eye morphology	retinal blood vessels	males	2.0 %	1.0
eye morphology	retinal blood vessels	both	6.0 %	0.184
eye morphology	retinal blood vessels pattern	females	11.0 %	0.216
eye morphology	retinal blood vessels pattern	males	2.0 %	1.00
eye morphology	retinal blood vessels pattern	both	6.0 %	0.263
eye morphology	retinal blood vessels structure	females	11.0 %	0.165
eye morphology	retinal blood vessels structure	males	2.0 %	1.0
eye morphology	retinal blood vessels structure	both	6.0 %	0.202
eye morphology	retinal pigmentation	females	11.0 %	0.317
eye morphology	retinal pigmentation	males	14.0 %	1.0
eye morphology	retinal pigmentation	both	6.0 %	0.401
eye morphology	retinal structure	females	11.0 %	0.167
eye morphology	retinal structure	males	2.0 %	1.00
eye morphology	retinal structure	both	6.0 %	0.209
eye morphology	synechia	females	11.0 %	0.161
eye morphology	synechia	males	2.0 %	1.00
eye morphology	synechia	both	6.0 %	0.188
eye morphology	vitreous	females	11.0 %	0.152
eye morphology	vitreous	males	2.0 %	1.0
eye morphology	vitreous	both	6.0 %	0.177
SHIRPA	activity body position	females	24.0 %	0.00297
SHIRPA	activity body position	males	2.0 %	1.0
SHIRPA	activity body position	both	12.0 %	0.0169
SHIRPA	aggression	females	12.0 %	0.0404
SHIRPA	aggression	males	1.0 %	1.0
SHIRPA	aggression	both	6.0 %	0.0825
SHIRPA	body length	females	0.0 %	1.0
SHIRPA	body length	males	0.0 %	1.0
SHIRPA	body length	both	0.0 %	1.0
SHIRPA	body position	females	12.0 %	0.0175
SHIRPA	body position	males	1.0 %	1.0
SHIRPA	body position	both	6.0 %	0.0592
SHIRPA	body thickness	females	1.0 %	1.0
SHIRPA	body thickness	males	0.0 %	1.0
SHIRPA	body thickness	both	0.0 %	1.00
SHIRPA	coat color abdomen	females	3.0 %	1.00
SHIRPA	coat color abdomen	males	4.0 %	1.00
SHIRPA	coat color abdomen	both	4.0 %	1.00
SHIRPA	coat color back	females	0.0 %	1.0
SHIRPA	coat color back	males	0.0 %	1.0
SHIRPA	coat color back	both	0.0 %	1.00
SHIRPA	coat color head	females	0.0 %	1.0
SHIRPA	coat color head	males	0.0 %	1.0
SHIRPA	coat color head	both	0.0 %	1.0
SHIRPA	coat color pattern abdomen	females	1.0 %	1.0
SHIRPA	coat color pattern abdomen	males	1.0 %	1.0
SHIRPA	coat color pattern abdomen	both	1.0 %	1.00
SHIRPA	coat color pattern back	females	0.0 %	1.0
SHIRPA	coat color pattern back	males	0.0 %	1.0
SHIRPA	coat color pattern back	both	0.0 %	1.00
SHIRPA	coat color pattern head	females	0.0 %	1.0
SHIRPA	coat color pattern head	males	0.0 %	1.00
SHIRPA	coat color pattern head	both	0.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	females	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	males	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	both	2.0 %	1.0
SHIRPA	coat hair back texture appearance	females	0.0 %	1.0
SHIRPA	coat hair back texture appearance	males	0.0 %	1.0
SHIRPA	coat hair back texture appearance	both	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	females	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	males	1.0 %	1.0
SHIRPA	coat hair distribution abdomen	both	1.0 %	1.0
SHIRPA	coat hair distribution back	females	0.0 %	1.0
SHIRPA	coat hair distribution back	males	0.0 %	1.0
SHIRPA	coat hair distribution back	both	0.0 %	1.00
SHIRPA	coat hair distribution head	females	1.0 %	1.00
SHIRPA	coat hair distribution head	males	1.0 %	1.0
SHIRPA	coat hair distribution head	both	1.0 %	1.0
SHIRPA	coat hair head texture appearance	females	0.0 %	1.00
SHIRPA	coat hair head texture appearance	males	0.0 %	1.0
SHIRPA	coat hair head texture appearance	both	0.0 %	1.0
SHIRPA	contact righting	females	5.0 %	1.0
SHIRPA	contact righting	males	5.0 %	1.00
SHIRPA	contact righting	both	5.0 %	1.00
SHIRPA	ear morphology	females	0.0 %	1.0
SHIRPA	ear morphology	males	0.0 %	1.0
SHIRPA	ear morphology	both	0.0 %	1.0
SHIRPA	fat distribution	females	0.0 %	1.0
SHIRPA	fat distribution	males	0.0 %	1.0
SHIRPA	fat distribution	both	0.0 %	1.0
SHIRPA	forelimb digit number	females	0.0 %	1.00
SHIRPA	forelimb digit number	males	0.0 %	1.0
SHIRPA	forelimb digit number	both	0.0 %	1.0
SHIRPA	forelimb digit position	females	0.0 %	1.0
SHIRPA	forelimb digit position	males	0.0 %	1.0
SHIRPA	forelimb digit position	both	0.0 %	1.0
SHIRPA	forelimb digit shape	females	0.0 %	1.0
SHIRPA	forelimb digit shape	males	0.0 %	1.0
SHIRPA	forelimb digit shape	both	0.0 %	1.0
SHIRPA	forelimb digit size	females	0.0 %	1.0
SHIRPA	forelimb digit size	males	0.0 %	1.0
SHIRPA	forelimb digit size	both	0.0 %	1.0
SHIRPA	forelimb footpads	females	0.0 %	1.0
SHIRPA	forelimb footpads	males	0.0 %	1.0
SHIRPA	forelimb footpads	both	0.0 %	1.0
SHIRPA	forelimb nail length	females	0.0 %	1.0
SHIRPA	forelimb nail length	males	0.0 %	1.0
SHIRPA	forelimb nail length	both	0.0 %	1.0
SHIRPA	forelimb nail number	females	0.0 %	1.0
SHIRPA	forelimb nail number	males	0.0 %	1.0
SHIRPA	forelimb nail number	both	0.0 %	1.0
SHIRPA	forelimb nail position	females	0.0 %	1.0
SHIRPA	forelimb nail position	males	0.0 %	1.0
SHIRPA	forelimb nail position	both	0.0 %	1.0
SHIRPA	forelimb nail shape	females	0.0 %	1.0
SHIRPA	forelimb nail shape	males	0.0 %	1.0
SHIRPA	forelimb nail shape	both	0.0 %	1.0
SHIRPA	forelimbs position	females	0.0 %	1.0
SHIRPA	forelimbs position	males	0.0 %	1.0
SHIRPA	forelimbs position	both	0.0 %	1.0
SHIRPA	forelimbs shape	females	0.0 %	1.0
SHIRPA	forelimbs shape	males	0.0 %	1.0
SHIRPA	forelimbs shape	both	0.0 %	1.0
SHIRPA	forelimbs size	females	0.0 %	1.0
SHIRPA	forelimbs size	males	0.0 %	1.00
SHIRPA	forelimbs size	both	0.0 %	1.0
SHIRPA	forepaw position	females	0.0 %	1.0
SHIRPA	forepaw position	males	0.0 %	1.0
SHIRPA	forepaw position	both	0.0 %	1.0
SHIRPA	forepaw shape	females	0.0 %	1.0
SHIRPA	forepaw shape	males	0.0 %	1.0
SHIRPA	forepaw shape	both	0.0 %	1.0
SHIRPA	forepaw size	females	0.0 %	1.0
SHIRPA	forepaw size	males	0.0 %	1.0
SHIRPA	forepaw size	both	0.0 %	1.0
SHIRPA	gait (fluidity)	females	0.0 %	1.0
SHIRPA	gait (fluidity)	males	0.0 %	1.0
SHIRPA	gait (fluidity)	both	0.0 %	1.0
SHIRPA	genitalia morphology	females	0.0 %	1.00
SHIRPA	genitalia morphology	males	0.0 %	1.0
SHIRPA	genitalia morphology	both	0.0 %	1.00
SHIRPA	genitalia presence	females	0.0 %	1.0
SHIRPA	genitalia presence	males	0.0 %	1.0
SHIRPA	genitalia presence	both	0.0 %	1.0
SHIRPA	genitalia size	females	0.0 %	1.0
SHIRPA	genitalia size	males	0.0 %	1.00
SHIRPA	genitalia size	both	0.0 %	1.00
SHIRPA	head bobbing	females	0.0 %	1.0
SHIRPA	head bobbing	males	0.0 %	1.0
SHIRPA	head bobbing	both	0.0 %	1.0
SHIRPA	head morphology	females	0.0 %	1.0
SHIRPA	head morphology	males	0.0 %	1.0
SHIRPA	head morphology	both	0.0 %	1.0
SHIRPA	head size	females	0.0 %	1.0
SHIRPA	head size	males	0.0 %	1.00
SHIRPA	head size	both	0.0 %	1.0
SHIRPA	hindlimb digit number	females	1.0 %	1.00
SHIRPA	hindlimb digit number	males	0.0 %	1.0
SHIRPA	hindlimb digit number	both	0.0 %	1.0
SHIRPA	hindlimb digit position	females	0.0 %	1.0
SHIRPA	hindlimb digit position	males	0.0 %	1.0
SHIRPA	hindlimb digit position	both	0.0 %	1.0
SHIRPA	hindlimb digit shape	females	0.0 %	1.0
SHIRPA	hindlimb digit shape	males	0.0 %	1.0
SHIRPA	hindlimb digit shape	both	0.0 %	1.00
SHIRPA	hindlimb digit size	females	0.0 %	1.00
SHIRPA	hindlimb digit size	males	0.0 %	1.00
SHIRPA	hindlimb digit size	both	0.0 %	1.00
SHIRPA	hindlimb nail length	females	0.0 %	1.0
SHIRPA	hindlimb nail length	males	0.0 %	1.00
SHIRPA	hindlimb nail length	both	0.0 %	1.0
SHIRPA	hindlimb nail number	females	0.0 %	1.0
SHIRPA	hindlimb nail number	males	1.0 %	1.00
SHIRPA	hindlimb nail number	both	0.0 %	1.0
SHIRPA	hindlimb nail position	females	0.0 %	1.0
SHIRPA	hindlimb nail position	males	0.0 %	1.0
SHIRPA	hindlimb nail position	both	0.0 %	1.0
SHIRPA	hindlimb nail shape	females	0.0 %	1.0
SHIRPA	hindlimb nail shape	males	0.0 %	1.0
SHIRPA	hindlimb nail shape	both	0.0 %	1.0
SHIRPA	hindlimbs footpads	females	0.0 %	1.0
SHIRPA	hindlimbs footpads	males	0.0 %	1.0
SHIRPA	hindlimbs footpads	both	0.0 %	1.0
SHIRPA	hindlimbs position	females	0.0 %	1.0
SHIRPA	hindlimbs position	males	0.0 %	1.0
SHIRPA	hindlimbs position	both	0.0 %	1.0
SHIRPA	hindlimbs shape	females	0.0 %	1.0
SHIRPA	hindlimbs shape	males	0.0 %	1.0
SHIRPA	hindlimbs shape	both	0.0 %	1.0
SHIRPA	hindlimbs size	females	0.0 %	1.0
SHIRPA	hindlimbs size	males	0.0 %	1.0
SHIRPA	hindlimbs size	both	0.0 %	1.0
SHIRPA	hindpaw position	females	0.0 %	1.0
SHIRPA	hindpaw position	males	0.0 %	1.0
SHIRPA	hindpaw position	both	0.0 %	1.0
SHIRPA	hindpaw shape	females	0.0 %	1.0
SHIRPA	hindpaw shape	males	0.0 %	1.0
SHIRPA	hindpaw shape	both	0.0 %	1.0
SHIRPA	hindpaw size	females	0.0 %	1.0
SHIRPA	hindpaw size	males	0.0 %	1.0
SHIRPA	hindpaw size	both	0.0 %	1.0
SHIRPA	limb grasp	females	4.0 %	0.524
SHIRPA	limb grasp	males	6.0 %	1.0
SHIRPA	limb grasp	both	1.0 %	1.0
SHIRPA	lower lip morphology	females	0.0 %	1.0
SHIRPA	lower lip morphology	males	0.0 %	1.0
SHIRPA	lower lip morphology	both	0.0 %	1.0
SHIRPA	lower teeth appearance	females	0.0 %	1.0
SHIRPA	lower teeth appearance	males	0.0 %	1.0
SHIRPA	lower teeth appearance	both	0.0 %	1.0
SHIRPA	mouth morphology	females	0.0 %	1.0
SHIRPA	mouth morphology	males	0.0 %	1.0
SHIRPA	mouth morphology	both	0.0 %	1.0
SHIRPA	salivation	females	0.0 %	1.0
SHIRPA	salivation	males	0.0 %	1.0
SHIRPA	salivation	both	0.0 %	1.0
SHIRPA	skin color back paws	females	0.0 %	1.0
SHIRPA	skin color back paws	males	0.0 %	1.0
SHIRPA	skin color back paws	both	0.0 %	1.0
SHIRPA	skin color ear	females	0.0 %	1.0
SHIRPA	skin color ear	males	0.0 %	1.0
SHIRPA	skin color ear	both	0.0 %	1.0
SHIRPA	skin color front paws	females	0.0 %	1.0
SHIRPA	skin color front paws	males	0.0 %	1.0
SHIRPA	skin color front paws	both	0.0 %	1.0
SHIRPA	skin color snout	females	0.0 %	1.0
SHIRPA	skin color snout	males	0.0 %	1.0
SHIRPA	skin color snout	both	0.0 %	1.0
SHIRPA	skin color tail	females	0.0 %	1.0
SHIRPA	skin color tail	males	0.0 %	1.0
SHIRPA	skin color tail	both	0.0 %	1.0
SHIRPA	skin color whole body	females	0.0 %	1.0
SHIRPA	skin color whole body	males	0.0 %	1.0
SHIRPA	skin color whole body	both	0.0 %	1.0
SHIRPA	skin texture back paw	females	0.0 %	1.0
SHIRPA	skin texture back paw	males	0.0 %	1.0
SHIRPA	skin texture back paw	both	0.0 %	1.0
SHIRPA	skin texture ear	females	0.0 %	1.0
SHIRPA	skin texture ear	males	0.0 %	1.0
SHIRPA	skin texture ear	both	0.0 %	1.0
SHIRPA	skin texture front paws	females	0.0 %	1.0
SHIRPA	skin texture front paws	males	0.0 %	1.0
SHIRPA	skin texture front paws	both	0.0 %	1.0
SHIRPA	skin texture snout	females	0.0 %	1.0
SHIRPA	skin texture snout	males	0.0 %	1.0
SHIRPA	skin texture snout	both	0.0 %	1.0
SHIRPA	skin texture tail	females	0.0 %	1.0
SHIRPA	skin texture tail	males	0.0 %	1.0
SHIRPA	skin texture tail	both	0.0 %	1.0
SHIRPA	skin texture whole body	females	0.0 %	1.0
SHIRPA	skin texture whole body	males	0.0 %	1.0
SHIRPA	skin texture whole body	both	0.0 %	1.00
SHIRPA	snout size	females	0.0 %	1.0
SHIRPA	snout size	males	1.0 %	1.0
SHIRPA	snout size	both	0.0 %	1.0
SHIRPA	startle response	females	0.0 %	1.00
SHIRPA	startle response	males	0.0 %	1.00
SHIRPA	startle response	both	0.0 %	1.0
SHIRPA	tail curvature	females	0.0 %	1.00
SHIRPA	tail curvature	males	0.0 %	1.0
SHIRPA	tail curvature	both	0.0 %	1.00
SHIRPA	tail elevation	females	1.0 %	1.00
SHIRPA	tail elevation	males	2.0 %	1.0
SHIRPA	tail elevation	both	1.0 %	1.0
SHIRPA	tail length	females	0.0 %	1.0
SHIRPA	tail length	males	0.0 %	1.00
SHIRPA	tail length	both	0.0 %	1.0
SHIRPA	tail morphology	females	0.0 %	1.00
SHIRPA	tail morphology	males	0.0 %	1.00
SHIRPA	tail morphology	both	0.0 %	1.00
SHIRPA	tail presence	females	0.0 %	1.0
SHIRPA	tail presence	males	0.0 %	1.0
SHIRPA	tail presence	both	0.0 %	1.0
SHIRPA	tail shape	females	0.0 %	1.0
SHIRPA	tail shape	males	0.0 %	1.0
SHIRPA	tail shape	both	0.0 %	1.0
SHIRPA	tail thickness	females	0.0 %	1.0
SHIRPA	tail thickness	males	0.0 %	1.0
SHIRPA	tail thickness	both	0.0 %	1.0
SHIRPA	teeth presence	females	0.0 %	1.0
SHIRPA	teeth presence	males	0.0 %	1.0
SHIRPA	teeth presence	both	0.0 %	1.0
SHIRPA	transfer arousal	females	24.0 %	0.00359
SHIRPA	transfer arousal	males	2.0 %	1.0
SHIRPA	transfer arousal	both	12.0 %	0.0185
SHIRPA	tremor	females	0.0 %	1.0
SHIRPA	tremor	males	0.0 %	1.0
SHIRPA	tremor	both	0.0 %	1.00
SHIRPA	trunk curl	females	0.0 %	1.00
SHIRPA	trunk curl	males	0.0 %	1.0
SHIRPA	trunk curl	both	0.0 %	1.00
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	females	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	males	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	both	0.0 %	1.0
SHIRPA	upper lip morphology	females	0.0 %	1.0
SHIRPA	upper lip morphology	males	0.0 %	1.0
SHIRPA	upper lip morphology	both	0.0 %	1.0
SHIRPA	upper teeth appearance	females	0.0 %	1.0
SHIRPA	upper teeth appearance	males	0.0 %	1.00
SHIRPA	upper teeth appearance	both	0.0 %	1.0
SHIRPA	vibrissae appearance	females	2.0 %	1.0
SHIRPA	vibrissae appearance	males	1.0 %	1.0
SHIRPA	vibrissae appearance	both	1.0 %	1.0
SHIRPA	vibrissae presence	females	2.0 %	1.00
SHIRPA	vibrissae presence	males	1.0 %	1.0
SHIRPA	vibrissae presence	both	2.0 %	1.0
SHIRPA	vocalization	females	2.0 %	1.00
SHIRPA	vocalization	males	2.0 %	1.00
SHIRPA	vocalization	both	2.0 %	1.0

GENOTYPE CORRELATION PLOT

Correlate Kansl3^em1(IMPC)J/Mmjax -/+ with genotype: