MPD: JaxKOMP-EAP genotype: Dync1li2<sup>em1(IMPC)J</sup>/Mmjax -/+

JaxKOMP-EAP effect sizes: Dync1li2^em1(IMPC)J/Mmjax -/+ Gene Dync1li2

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

In this plot, data points are the computed genotype effect size vs. C57BL/6NJ controls, for all measured numeric phenotypes in JaxKOMP-EAP

Dimensions Width: × Height: px

Plot Options Group by Procedure Standard Error Show Effect Sizes RankZ

Significance Threshold p-Value Threshold Adjusted Unadjusted

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Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value

ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	0.17433	2.2368	-0.23405	0.984	0.939
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	-2.5000	3.4344	-0.53696	0.831	0.478
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	-0.59199	2.3840	-0.29909	0.939	0.807
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	-2.0833	4.7668	-0.45817	0.878	0.668
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	-8.9583	5.3088	-1.2345	0.472	0.112
body composition	body length	0.11086	0.050937	1.5389	0.197	0.0384
body composition	body weight (at time of DXA)	-0.35486	0.57440	-0.19291	0.738	0.542
body composition	bone area, whole body scan, head excluded	0.31315	0.13270	1.4944	0.146	0.0258
body composition	bone mineral content of whole body scan, head excluded	0.021804	0.011489	1.3724	0.261	0.0685
body composition	bone mineral content to body weight ratio	0.0010047	0.00042668	1.4500	0.137	0.0258
body composition	bone mineral density of whole body scan, head excluded	0.00047458	0.00070395	0.55203	0.753	0.506
body composition	fat tissue mass of whole body scan, head excluded	-0.62885	0.31232	-1.1677	0.217	0.0541
body composition	fat tissue mass to body weight ratio	-0.025650	0.010353	-1.1517	0.106	0.0198
body composition	lean tissue mass of whole body scan, head excluded	0.62152	0.27102	1.0374	0.189	0.0298
body composition	lean tissue mass to body weight ratio	0.029508	0.0086652	1.4536	0.0365	0.00208
body composition	percent fat, whole body scan, head excluded	-2.5256	0.98343	-1.2036	0.0974	0.0161
body composition	ratio of soft-tissue attenuation coefficients	0.0028339	0.0010918	1.2165	0.0940	0.0151
body composition	tissue area	-0.46424	0.11284	-1.2674	0.0117	0.000327
body composition	total tissue mass, whole body scan, head excluded	-0.11073	0.17514	-0.48532	0.738	0.533
clinical blood chemistry	alanine transaminase (plasma ALT)	3.0386	5.2675	0.26742	0.869	0.604
clinical blood chemistry	albumin (plasma Alb)	-0.92344	1.0494	-1.1636	0.735	0.444
clinical blood chemistry	alkaline phosphatase (plasma ALP)	-1.8452	4.3030	-0.85135	0.846	0.697
clinical blood chemistry	aspartate transaminase (plasma AST)	10.635	11.535	0.46574	0.723	0.425
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	0.021801	0.36168	0.098094	0.988	0.956
clinical blood chemistry	blood urea nitrogen (BUN)	-0.37226	1.2647	-0.18230	0.901	0.788
clinical blood chemistry	calcium (plasma Ca)	0.14098	0.23384	1.2858	0.771	0.589
clinical blood chemistry	creatinine (plasma)	0.074006	0.15903	1.7707	0.824	0.673
clinical blood chemistry	glucose (plasma GLU, no fast)	-11.535	16.231	-0.15704	0.715	0.529
clinical blood chemistry	HDL cholesterol (plasma HDL)	-1.3424	7.2526	-0.64848	0.955	0.865
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	-0.011149	0.0092555	-0.75963	0.642	0.315
clinical blood chemistry	phosphorus (plasma phosphate)	2.7990	3.5556	2.4975	0.744	0.489
clinical blood chemistry	total bilirubin (plasma TBIL)	-0.010730	0.0067676	-0.79831	0.556	0.211
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	-0.25996	11.239	-0.28312	0.995	0.983
clinical blood chemistry	total protein (plasma TP)	-1.6998	1.1548	-1.2900	0.517	0.237
clinical blood chemistry	triglyceride (plasma TG, no fast)	13.468	14.380	0.91180	0.689	0.418
EKG	duration of PQ interval	-0.53236	0.92979	-0.43441	0.924	0.572
EKG	duration of PR interval	-0.67303	0.91791	-0.59079	0.901	0.470
EKG	duration of QRS interval	-0.33647	0.31807	-1.0214	0.885	0.300
EKG	duration of QT interval	0.61997	1.0034	0.75783	0.898	0.542
EKG	duration of QTC interval, calculated by dividing QT interval by square root of preceding RR interval	0.63919	1.0615	0.75783	0.925	0.552
EKG	duration of RR interval	0.20591	0.82154	0.34098	0.932	0.804
EKG	duration of ST interval	0.94907	1.0193	1.1965	0.792	0.360
EKG	heart rate coefficient of variation (signal intensity)	-0.99758	0.99789	-0.74713	0.867	0.326
EKG	heart rate variability, mean of differences between sequential beats; beats per min	-7.7084	7.5848	-0.84392	0.853	0.319
EKG	heart rate, beats per min	-3.2474	7.6605	-0.44924	0.876	0.675
EKG	mean R amplitude, mean amplitude of signal measured from isoelectric line to peak of QRS	0.010453	0.089211	-0.045389	0.972	0.908
EKG	mean SR amplitude, mean amplitude of signal measured from signal minimum line to peak of QRS	0.0099495	0.14970	-0.019159	0.981	0.948
EKG	number of signals	7.1036	8.8063	1.2697	0.854	0.427
EKG	proportion of number pairs of successive beat-to-beat intervals that exceed 50 ms	-3.1093	5.9056	-0.50027	0.903	0.603
EKG	QT dispersion, measured as inter-lead variability of QT intervals	0.34024	2.8667	0.13948	0.989	0.906
EKG	QTc dispersion, calculated as rate-corrected QT dispersion	0.49736	3.2010	0.14152	0.986	0.878
EKG	root mean square of successive differences of neighboring RR intervals	-1.9571	1.6033	-1.0180	0.843	0.233
glucose tolerance test	amount glucose injected	-4.4302	2.1469	-0.90112	0.321	0.0488
glucose tolerance test	plasma glucose, 0min	10.103	4.8389	0.79971	0.155	0.0460
glucose tolerance test	plasma glucose, 15min	40.279	20.382	1.2003	0.283	0.0584
glucose tolerance test	plasma glucose, 30min	-14.073	18.045	-0.31539	0.732	0.442
glucose tolerance test	plasma glucose, 60min	3.1297	16.397	0.27239	0.935	0.850
glucose tolerance test	plasma glucose, 120min	9.6936	7.4133	0.54149	0.510	0.202
grip strength	body weight (at time of grip strength test)	-0.26404	0.52541	-0.036273	0.769	0.618
grip strength	forelimb and hindlimb grip strength (mean of trials), average	-17.219	5.2084	-0.92575	0.0196	0.00215
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	-0.63768	0.23299	-0.74454	0.0573	0.00957
grip strength	forelimb and hindlimb grip strength by trial, trial1	-15.536	7.9395	-0.77949	0.247	0.0582
grip strength	forelimb and hindlimb grip strength by trial, trial2	-19.760	7.4426	-1.0020	0.0890	0.0117
grip strength	forelimb and hindlimb grip strength by trial, trial3	-14.570	6.2982	-0.73690	0.149	0.0265
grip strength	forelimb grip strength (mean of trials), average	-9.4480	3.1368	-0.86926	0.0484	0.00466
grip strength	forelimb grip strength (mean of trials), average normalized to bw	-0.35148	0.14273	-0.65547	0.114	0.0187
grip strength	forelimb grip strength by trial, trial1	-9.0730	4.1975	-0.78343	0.256	0.0374
grip strength	forelimb grip strength by trial, trial2	-5.9214	5.0625	-0.42013	0.572	0.250
grip strength	forelimb grip strength by trial, trial3	-12.105	4.5551	-1.0312	0.121	0.0116
heart weight	heart weight, normalized to body weight	0.43110	0.19432	0.92755	0.167	0.0466
heart weight	heart weight, weight	8.2054	6.4649	0.69456	0.441	0.231
hematology	basophil differential (percent of total WBC)	0.060178	0.12039	0.88995	0.892	0.652
hematology	calculated hemoglobin (cHGB)	-0.022797	0.33661	-0.36239	0.983	0.950
hematology	eosinophil differential (percent of total WBC)	0.22795	0.53042	0.71850	0.903	0.696
hematology	hematocrit (HCT)	0.049114	0.62293	-0.32260	0.973	0.942
hematology	hemoglobin concentration distribution width (HDW)	0.034432	0.076096	0.90631	0.855	0.682
hematology	large unstained cells (percent of total WBC)	-0.10506	0.28179	-0.71821	0.890	0.734
hematology	lymphocyte differential (percent of total WBC)	-1.3615	2.0173	-0.62802	0.747	0.548
hematology	mean corpuscular hemoglobin (CHr)	-0.084055	0.10143	-0.69415	0.700	0.468
hematology	mean platelet volume (MPV)	0.012934	0.25941	-0.10101	0.982	0.963
hematology	mean RBC corpuscular hemoglobin (MCH)	-0.27867	0.16451	-0.86367	0.533	0.189
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	-0.39715	0.42513	-0.75678	0.747	0.419
hematology	mean RBC corpuscular volume (MCV)	-0.17596	0.86820	-0.32692	0.939	0.852
hematology	measured hemoglobin (mHGB)	-0.16234	0.32079	-0.63593	0.830	0.648
hematology	monocyte differential (percent of total WBC)	0.095719	0.20305	0.54363	0.879	0.670
hematology	neutrophil differential (percent of total WBC)	1.0674	2.0646	0.55316	0.809	0.641
hematology	platelet count (PLT; units per volume x 10³)	56.707	71.278	0.79914	0.775	0.484
hematology	RBC corpuscular distribution width (RDW)	0.085889	0.39334	0.30982	0.926	0.841
hematology	RBC corpuscular hemoglobin concentration mean (CHCM)	-0.051276	0.64210	-0.17143	0.974	0.941
hematology	red blood cell count (RBC; per volume x 10⁶)	0.044669	0.21604	-0.14693	0.929	0.849
hematology	reticulocyte count (Retic; units per volume x 10⁹)	-6.7699	19.770	-0.20961	0.927	0.755
hematology	reticulocyte differential (percent of total RBC)	-0.095036	0.14711	-0.18893	0.824	0.564
hematology	white blood cell count (WBC; units per volume x 10³)	1.3067	1.4289	1.0437	0.621	0.428
holeboard	number of hole pokes by individual hole number, 20 min test, 1	0.25570	0.57217	0.32019	0.899	0.657
holeboard	number of hole pokes by individual hole number, 20 min test, 2	-0.28539	0.58693	-0.32731	0.904	0.629
holeboard	number of hole pokes by individual hole number, 20 min test, 3	0.37500	0.51062	0.70500	0.864	0.466
holeboard	number of hole pokes by individual hole number, 20 min test, 4	0.92500	0.70394	0.98235	0.667	0.195
holeboard	number of hole pokes by individual hole number, 20 min test, 5	0.46250	0.50723	0.82017	0.806	0.366
holeboard	number of hole pokes by individual hole number, 20 min test, 6	-0.12500	0.32496	-0.32975	0.953	0.702
holeboard	number of hole pokes by individual hole number, 20 min test, 7	0.12500	0.26930	0.34207	0.958	0.645
holeboard	number of hole pokes by individual hole number, 20 min test, 8	0.50000	0.40421	0.96877	0.752	0.222
holeboard	number of hole pokes by individual hole number, 20 min test, 9	0.28750	0.44374	0.61420	0.893	0.520
holeboard	number of hole pokes by individual hole number, 20 min test, 10	-0.049339	0.24105	-0.052457	0.964	0.839
holeboard	number of hole pokes by individual hole number, 20 min test, 11	-0.21364	0.31070	-0.57191	0.884	0.495
holeboard	number of hole pokes by individual hole number, 20 min test, 12	0.31829	0.28255	0.61938	0.715	0.265
holeboard	number of hole pokes by individual hole number, 20 min test, 13	-0.33771	0.57365	-0.24882	0.854	0.559
holeboard	number of hole pokes by individual hole number, 20 min test, 14	0.82500	0.56792	1.2800	0.581	0.153
holeboard	number of hole pokes by individual hole number, 20 min test, 15	0.66250	0.41291	1.1081	0.582	0.115
holeboard	number of hole pokes by individual hole number, 20 min test, 16	0.84986	0.77129	0.75845	0.686	0.276
holeboard	total number of hole pokes, 20 min test	4.3750	3.6418	0.69690	0.528	0.235
light / dark	latency to enter dark zone, 20 min test	10.340	38.393	0.10429	0.948	0.789
light / dark	number of transitions between light and dark zones, 20 min test	9.6027	8.3773	0.98484	0.584	0.258
light / dark	percentage of total time in dark zone, 20 min test	-6.5289	3.0768	-1.0229	0.312	0.0394
light / dark	percentage of total time in light zone, 20 min test	6.5289	3.0768	1.0183	0.308	0.0394
light / dark	time mobile in dark zone, 20 min test	4.4878	10.416	0.21389	0.856	0.669
light / dark	time mobile in light zone, 20 min test	33.070	11.251	1.4135	0.0529	0.00522
light / dark	time spent in dark zone, 20 min test	-82.230	43.510	-0.97175	0.417	0.0652
light / dark	time spent in light zone, 20 min test	82.230	43.510	0.97175	0.417	0.0652
open field	average speed in center of arena, 20 min test	0.93261	0.30743	1.4511	0.0885	0.00517
open field	average speed in periphery of arena, 20 min test	0.53328	0.16448	1.3475	0.0257	0.00298
open field	distance traveled habituation ratio, 20 min test	-4.7225	6.5864	-0.36436	0.750	0.479
open field	distance traveled in center of arena, 20 min test	-26.371	137.93	-0.55249	0.919	0.850
open field	distance traveled in periphery of arena, 20 min test	464.54	173.38	1.2746	0.0793	0.0120
open field	distance traveled slope, 20 min test	-4.3846	7.0558	-0.34292	0.797	0.539
open field	distance traveled, 20 min test, 1st 5min	106.51	61.963	0.50311	0.284	0.0963
open field	distance traveled, 20 min test, 2nd 5min	108.43	45.685	0.68082	0.122	0.0245
open field	distance traveled, 20 min test, 3rd 5min	268.63	76.643	1.8654	0.0197	0.00150
open field	distance traveled, 20 min test, 4th 5min	116.85	62.211	0.78080	0.240	0.0704
open field	number of clockwise revolution episodes, 20 min test	2.6814	1.7509	1.0454	0.475	0.137
open field	number of counter-clockwise revolution episodes, 20 min test	0.83559	1.2372	0.026184	0.737	0.505
open field	number of rears in 5 min bins, 20 min test, 1st 5min	3.0626	2.5027	0.63209	0.496	0.231
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	1.2960	3.7663	-0.036930	0.877	0.733
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	-0.086440	3.5458	-0.31882	0.988	0.981
open field	number of rears in 5 min bins, 20 min test, 4th 5min	0.59463	4.1102	-0.23095	0.944	0.886
open field	percentage of total time in center of arena, 20 min test	-6.2275	4.5055	-1.7304	0.489	0.178
open field	percentage of total time in center of arena, slope, 20 min test	-0.56410	1.5085	-0.19798	0.941	0.711
open field	percentage of total time in center, habituation ratio, 20 min test	-0.57545	1.3908	-0.18157	0.907	0.682
open field	percentage of total time in corners of arena, 20 min test	5.4797	4.4694	1.2898	0.544	0.230
open field	percentage of total time in corners, habituation ratio, 20 min test	0.46110	2.2458	-0.066508	0.969	0.839
open field	percentage of total time in corners, slope, 20 min test	0.45654	2.3106	-0.058436	0.967	0.845
open field	permanence time in center of arena, 20 min test	-74.747	54.063	-1.7304	0.490	0.178
open field	permanence time in corners of arena, 20 min test	65.768	53.630	1.2898	0.544	0.230
open field	permanence time in periphery of arena, 20 min test	74.720	54.068	1.7244	0.489	0.178
open field	total distance traveled, 20 min test	611.51	218.00	1.1461	0.0504	0.00889
open field	total number of rears, 20 min test	5.3792	12.884	0.035586	0.840	0.679
open field	whole arena average speed, 20 min test	0.50624	0.18198	1.1358	0.0524	0.00940
open field	whole arena resting time, 20 min test	-66.292	23.044	-1.1487	0.0439	0.00746
open field	whole arena time spent mobile, 20 min test	66.501	23.017	1.3409	0.0450	0.00724
open field	whole arena time spent vertical, 20 min test	2.4369	12.561	0.081317	0.936	0.848
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	2.3814	1.2430	1.1724	0.287	0.0611
startle / PPI	average baseline movement during background noise	-2.4426	1.4787	-1.5852	0.628	0.106
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	0.043700	0.053297	0.30962	0.745	0.417
startle / PPI	average of each corrected percent pre-pulse inhibition value	0.040569	0.052734	0.32030	0.766	0.446
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-8.1187	6.2204	-0.83326	0.853	0.198
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	5.5645	5.7790	0.50155	0.682	0.341
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	7.0316	5.0461	0.64531	0.457	0.170
startle / PPI	average startle response to full pulse (120 dB)	-79.844	40.033	-1.1602	0.186	0.0522
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-52.421	41.063	-0.77518	0.438	0.208
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-70.970	37.565	-1.1148	0.211	0.0653
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-59.604	32.855	-1.1226	0.239	0.0763
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	-1.2419	1.3484	-0.84122	0.819	0.362
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	0.050189	1.5499	0.069412	0.996	0.974
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	-0.32426	2.1395	-0.34213	0.972	0.880
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.085341	0.065568	-0.76952	0.850	0.200
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.080689	0.065435	0.59512	0.570	0.224
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.12145	0.067404	0.76534	0.260	0.0783
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	-77.465	39.998	-1.1044	0.197	0.0591
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	-51.179	41.378	-0.75081	0.453	0.223
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	-71.020	38.191	-1.1174	0.219	0.0695
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	-59.435	33.615	-1.0865	0.246	0.0838
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.073877	0.064171	-0.64186	0.849	0.256
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.074110	0.066706	0.49629	0.622	0.273
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.12592	0.068748	0.72828	0.254	0.0736
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	-306.78	147.53	-1.2500	0.167	0.0433
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	-196.21	152.58	-0.81555	0.438	0.205
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	-270.16	140.55	-1.1769	0.199	0.0609
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	-241.81	124.09	-1.1910	0.194	0.0576
startle / PPI	maximum baseline movement during background noise	-4.8358	2.9901	-1.2876	0.596	0.113
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-7.9605	6.2097	-0.74895	0.884	0.206
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	5.9286	6.0871	0.45753	0.684	0.335
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	8.3843	5.6890	0.66092	0.415	0.148
startle / PPI	maximum startle response to full pulse (120 dB)	-311.46	147.68	-1.2655	0.161	0.0405
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-197.81	151.91	-0.83525	0.429	0.199
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-270.68	139.03	-1.1825	0.192	0.0578
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-242.13	122.68	-1.1967	0.190	0.0546
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	-1.5960	3.2510	-0.41133	0.912	0.626
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	-0.51420	3.7908	-0.13421	0.988	0.893
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	-0.32349	4.9394	-0.23833	0.991	0.948

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

In this plot, data points are the computed genotype effect % vs. C57BL/6NJ controls, for all measured categorical phenotypes in JaxKOMP-EAP

Dimensions Width: × Height: px

Plot Options Group by Procedure

Include Sexes Data Both Females Males

Significance Threshold p-Value Threshold

Download Plot

Procedure	JaxKOMP-EAP Trait	Sex	Trait Effect	P-value

eye morphology	anterior chamber depth	females	1.0 %	1.0
eye morphology	anterior chamber depth	males	0.0 %	1.0
eye morphology	anterior chamber depth	both	1.0 %	1.0
eye morphology	bulging eye	females	1.0 %	1.0
eye morphology	bulging eye	males	0.0 %	1.0
eye morphology	bulging eye	both	1.0 %	1.00
eye morphology	cornea	females	4.0 %	1.0
eye morphology	cornea	males	12.0 %	0.119
eye morphology	cornea	both	6.0 %	0.248
eye morphology	cornea opacity	females	9.0 %	0.359
eye morphology	cornea opacity	males	1.0 %	1.0
eye morphology	cornea opacity	both	4.0 %	0.428
eye morphology	cornea vascularization	females	3.0 %	1.0
eye morphology	cornea vascularization	males	1.0 %	1.0
eye morphology	cornea vascularization	both	2.0 %	1.00
eye morphology	corneal deposits	females	2.0 %	1.0
eye morphology	corneal deposits	males	1.0 %	1.0
eye morphology	corneal deposits	both	1.0 %	1.00
eye morphology	corneal mineralization	females	2.0 %	1.0
eye morphology	corneal mineralization	males	1.0 %	1.0
eye morphology	corneal mineralization	both	1.0 %	1.00
eye morphology	corneal scleralization	females	3.0 %	1.00
eye morphology	corneal scleralization	males	1.0 %	1.0
eye morphology	corneal scleralization	both	2.0 %	1.00
eye morphology	corneal ulcer	females	1.0 %	1.0
eye morphology	corneal ulcer	males	1.0 %	1.0
eye morphology	corneal ulcer	both	1.0 %	1.00
eye morphology	eye closure	females	1.0 %	1.00
eye morphology	eye closure	males	0.0 %	1.0
eye morphology	eye closure	both	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	females	2.0 %	1.00
eye morphology	eye hemorrhage or blood presence	males	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	both	1.0 %	1.00
eye morphology	eyelid morphology	females	1.0 %	1.0
eye morphology	eyelid morphology	males	0.0 %	1.0
eye morphology	eyelid morphology	both	1.0 %	1.0
eye morphology	eyes (present, absent)	females	1.0 %	1.0
eye morphology	eyes (present, absent)	males	0.0 %	1.0
eye morphology	eyes (present, absent)	both	0.0 %	1.0
eye morphology	fusion between cornea and lens	females	4.0 %	1.00
eye morphology	fusion between cornea and lens	males	2.0 %	1.0
eye morphology	fusion between cornea and lens	both	3.0 %	1.00
eye morphology	iris pigmentation	females	2.0 %	1.0
eye morphology	iris pigmentation	males	1.0 %	1.0
eye morphology	iris pigmentation	both	2.0 %	1.00
eye morphology	iris transillumination	females	2.0 %	1.00
eye morphology	iris transillumination	males	1.0 %	1.0
eye morphology	iris transillumination	both	1.0 %	1.00
eye morphology	irispupil	females	12.0 %	0.0969
eye morphology	irispupil	males	3.0 %	1.0
eye morphology	irispupil	both	5.0 %	0.301
eye morphology	lacrimation	females	3.0 %	1.0
eye morphology	lacrimation	males	2.0 %	1.0
eye morphology	lacrimation	both	3.0 %	1.0
eye morphology	lens	females	10.0 %	1.00
eye morphology	lens	males	8.0 %	1.0
eye morphology	lens	both	9.0 %	1.0
eye morphology	lens opacity	females	9.0 %	1.0
eye morphology	lens opacity	males	6.0 %	1.0
eye morphology	lens opacity	both	7.0 %	1.00
eye morphology	narrow eye opening	females	2.0 %	1.0
eye morphology	narrow eye opening	males	1.0 %	1.0
eye morphology	narrow eye opening	both	1.0 %	1.0
eye morphology	optic disc	females	4.0 %	1.00
eye morphology	optic disc	males	2.0 %	1.0
eye morphology	optic disc	both	3.0 %	1.00
eye morphology	persistence of hyaloid vascular system	females	31.0 %	0.145
eye morphology	persistence of hyaloid vascular system	males	5.0 %	1.0
eye morphology	persistence of hyaloid vascular system	both	14.0 %	0.232
eye morphology	pupil dilation	females	2.0 %	1.0
eye morphology	pupil dilation	males	1.0 %	1.0
eye morphology	pupil dilation	both	2.0 %	1.0
eye morphology	pupil light response	females	2.0 %	1.00
eye morphology	pupil light response	males	1.0 %	1.0
eye morphology	pupil light response	both	2.0 %	1.00
eye morphology	pupil position	females	12.0 %	0.213
eye morphology	pupil position	males	3.0 %	1.0
eye morphology	pupil position	both	5.0 %	0.321
eye morphology	pupil shape	females	3.0 %	1.00
eye morphology	pupil shape	males	2.0 %	1.0
eye morphology	pupil shape	both	3.0 %	1.00
eye morphology	retina	females	22.0 %	0.134
eye morphology	retina	males	16.0 %	1.0
eye morphology	retina	both	8.0 %	0.589
eye morphology	retinal blood vessels	females	4.0 %	1.0
eye morphology	retinal blood vessels	males	2.0 %	1.0
eye morphology	retinal blood vessels	both	3.0 %	1.0
eye morphology	retinal blood vessels pattern	females	5.0 %	1.0
eye morphology	retinal blood vessels pattern	males	2.0 %	1.0
eye morphology	retinal blood vessels pattern	both	4.0 %	1.00
eye morphology	retinal blood vessels structure	females	4.0 %	1.00
eye morphology	retinal blood vessels structure	males	2.0 %	1.0
eye morphology	retinal blood vessels structure	both	3.0 %	1.00
eye morphology	retinal pigmentation	females	12.0 %	1.0
eye morphology	retinal pigmentation	males	14.0 %	1.0
eye morphology	retinal pigmentation	both	13.0 %	1.0
eye morphology	retinal structure	females	4.0 %	1.00
eye morphology	retinal structure	males	2.0 %	1.0
eye morphology	retinal structure	both	3.0 %	1.00
eye morphology	synechia	females	4.0 %	1.0
eye morphology	synechia	males	2.0 %	1.0
eye morphology	synechia	both	3.0 %	1.00
eye morphology	vitreous	females	4.0 %	1.00
eye morphology	vitreous	males	2.0 %	1.0
eye morphology	vitreous	both	3.0 %	1.00
SHIRPA	activity body position	females	1.0 %	1.0
SHIRPA	activity body position	males	2.0 %	1.0
SHIRPA	activity body position	both	1.0 %	1.00
SHIRPA	aggression	females	0.0 %	1.00
SHIRPA	aggression	males	1.0 %	1.0
SHIRPA	aggression	both	1.0 %	1.0
SHIRPA	body length	females	0.0 %	1.0
SHIRPA	body length	males	0.0 %	1.00
SHIRPA	body length	both	0.0 %	1.00
SHIRPA	body position	females	0.0 %	1.0
SHIRPA	body position	males	1.0 %	1.0
SHIRPA	body position	both	0.0 %	1.0
SHIRPA	body thickness	females	1.0 %	1.0
SHIRPA	body thickness	males	0.0 %	1.0
SHIRPA	body thickness	both	0.0 %	1.0
SHIRPA	coat color abdomen	females	47.0 %	0.000103
SHIRPA	coat color abdomen	males	96.0 %	4.02e-12
SHIRPA	coat color abdomen	both	71.0 %	9.31e-15
SHIRPA	coat color back	females	0.0 %	1.0
SHIRPA	coat color back	males	0.0 %	1.00
SHIRPA	coat color back	both	0.0 %	1.00
SHIRPA	coat color head	females	0.0 %	1.0
SHIRPA	coat color head	males	0.0 %	1.00
SHIRPA	coat color head	both	0.0 %	1.0
SHIRPA	coat color pattern abdomen	females	1.0 %	1.0
SHIRPA	coat color pattern abdomen	males	1.0 %	1.0
SHIRPA	coat color pattern abdomen	both	1.0 %	1.0
SHIRPA	coat color pattern back	females	0.0 %	1.0
SHIRPA	coat color pattern back	males	0.0 %	1.00
SHIRPA	coat color pattern back	both	0.0 %	1.0
SHIRPA	coat color pattern head	females	0.0 %	1.0
SHIRPA	coat color pattern head	males	0.0 %	1.0
SHIRPA	coat color pattern head	both	0.0 %	1.00
SHIRPA	coat hair abdomen texture appearance	females	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	males	35.0 %	0.000848
SHIRPA	coat hair abdomen texture appearance	both	17.0 %	0.00403
SHIRPA	coat hair back texture appearance	females	0.0 %	1.0
SHIRPA	coat hair back texture appearance	males	0.0 %	1.0
SHIRPA	coat hair back texture appearance	both	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	females	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	males	36.0 %	0.0000894
SHIRPA	coat hair distribution abdomen	both	18.0 %	0.000167
SHIRPA	coat hair distribution back	females	0.0 %	1.0
SHIRPA	coat hair distribution back	males	12.0 %	0.0206
SHIRPA	coat hair distribution back	both	6.0 %	0.0349
SHIRPA	coat hair distribution head	females	1.0 %	1.00
SHIRPA	coat hair distribution head	males	1.0 %	1.0
SHIRPA	coat hair distribution head	both	1.0 %	1.0
SHIRPA	coat hair head texture appearance	females	0.0 %	1.00
SHIRPA	coat hair head texture appearance	males	0.0 %	1.0
SHIRPA	coat hair head texture appearance	both	0.0 %	1.0
SHIRPA	contact righting	females	5.0 %	1.0
SHIRPA	contact righting	males	5.0 %	1.00
SHIRPA	contact righting	both	5.0 %	1.00
SHIRPA	ear morphology	females	0.0 %	1.0
SHIRPA	ear morphology	males	0.0 %	1.0
SHIRPA	ear morphology	both	0.0 %	1.0
SHIRPA	fat distribution	females	0.0 %	1.0
SHIRPA	fat distribution	males	0.0 %	1.0
SHIRPA	fat distribution	both	0.0 %	1.00
SHIRPA	forelimb digit number	females	0.0 %	1.00
SHIRPA	forelimb digit number	males	0.0 %	1.0
SHIRPA	forelimb digit number	both	0.0 %	1.00
SHIRPA	forelimb digit position	females	0.0 %	1.0
SHIRPA	forelimb digit position	males	0.0 %	1.0
SHIRPA	forelimb digit position	both	0.0 %	1.0
SHIRPA	forelimb digit shape	females	0.0 %	1.0
SHIRPA	forelimb digit shape	males	0.0 %	1.0
SHIRPA	forelimb digit shape	both	0.0 %	1.0
SHIRPA	forelimb digit size	females	0.0 %	1.0
SHIRPA	forelimb digit size	males	0.0 %	1.0
SHIRPA	forelimb digit size	both	0.0 %	1.0
SHIRPA	forelimb footpads	females	0.0 %	1.0
SHIRPA	forelimb footpads	males	0.0 %	1.0
SHIRPA	forelimb footpads	both	0.0 %	1.0
SHIRPA	forelimb nail length	females	0.0 %	1.0
SHIRPA	forelimb nail length	males	0.0 %	1.0
SHIRPA	forelimb nail length	both	0.0 %	1.0
SHIRPA	forelimb nail number	females	0.0 %	1.0
SHIRPA	forelimb nail number	males	0.0 %	1.0
SHIRPA	forelimb nail number	both	0.0 %	1.0
SHIRPA	forelimb nail position	females	0.0 %	1.0
SHIRPA	forelimb nail position	males	0.0 %	1.0
SHIRPA	forelimb nail position	both	0.0 %	1.0
SHIRPA	forelimb nail shape	females	0.0 %	1.0
SHIRPA	forelimb nail shape	males	0.0 %	1.0
SHIRPA	forelimb nail shape	both	0.0 %	1.0
SHIRPA	forelimbs position	females	0.0 %	1.0
SHIRPA	forelimbs position	males	0.0 %	1.0
SHIRPA	forelimbs position	both	0.0 %	1.0
SHIRPA	forelimbs shape	females	0.0 %	1.0
SHIRPA	forelimbs shape	males	0.0 %	1.0
SHIRPA	forelimbs shape	both	0.0 %	1.0
SHIRPA	forelimbs size	females	0.0 %	1.0
SHIRPA	forelimbs size	males	0.0 %	1.0
SHIRPA	forelimbs size	both	0.0 %	1.0
SHIRPA	forepaw position	females	0.0 %	1.0
SHIRPA	forepaw position	males	0.0 %	1.0
SHIRPA	forepaw position	both	0.0 %	1.0
SHIRPA	forepaw shape	females	0.0 %	1.0
SHIRPA	forepaw shape	males	0.0 %	1.0
SHIRPA	forepaw shape	both	0.0 %	1.0
SHIRPA	forepaw size	females	0.0 %	1.0
SHIRPA	forepaw size	males	0.0 %	1.0
SHIRPA	forepaw size	both	0.0 %	1.0
SHIRPA	gait (fluidity)	females	0.0 %	1.0
SHIRPA	gait (fluidity)	males	0.0 %	1.00
SHIRPA	gait (fluidity)	both	0.0 %	1.00
SHIRPA	genitalia morphology	females	0.0 %	1.00
SHIRPA	genitalia morphology	males	0.0 %	1.0
SHIRPA	genitalia morphology	both	0.0 %	1.00
SHIRPA	genitalia presence	females	0.0 %	1.0
SHIRPA	genitalia presence	males	0.0 %	1.0
SHIRPA	genitalia presence	both	0.0 %	1.0
SHIRPA	genitalia size	females	0.0 %	1.0
SHIRPA	genitalia size	males	0.0 %	1.0
SHIRPA	genitalia size	both	0.0 %	1.0
SHIRPA	head bobbing	females	12.0 %	0.00294
SHIRPA	head bobbing	males	0.0 %	1.0
SHIRPA	head bobbing	both	6.0 %	0.00589
SHIRPA	head morphology	females	12.0 %	0.00879
SHIRPA	head morphology	males	0.0 %	1.00
SHIRPA	head morphology	both	6.0 %	0.0320
SHIRPA	head size	females	0.0 %	1.0
SHIRPA	head size	males	0.0 %	1.0
SHIRPA	head size	both	0.0 %	1.00
SHIRPA	hindlimb digit number	females	1.0 %	1.00
SHIRPA	hindlimb digit number	males	0.0 %	1.0
SHIRPA	hindlimb digit number	both	0.0 %	1.00
SHIRPA	hindlimb digit position	females	0.0 %	1.0
SHIRPA	hindlimb digit position	males	0.0 %	1.0
SHIRPA	hindlimb digit position	both	0.0 %	1.0
SHIRPA	hindlimb digit shape	females	0.0 %	1.0
SHIRPA	hindlimb digit shape	males	0.0 %	1.0
SHIRPA	hindlimb digit shape	both	0.0 %	1.0
SHIRPA	hindlimb digit size	females	0.0 %	1.00
SHIRPA	hindlimb digit size	males	0.0 %	1.0
SHIRPA	hindlimb digit size	both	0.0 %	1.00
SHIRPA	hindlimb nail length	females	0.0 %	1.0
SHIRPA	hindlimb nail length	males	0.0 %	1.0
SHIRPA	hindlimb nail length	both	0.0 %	1.00
SHIRPA	hindlimb nail number	females	0.0 %	1.0
SHIRPA	hindlimb nail number	males	1.0 %	1.0
SHIRPA	hindlimb nail number	both	0.0 %	1.00
SHIRPA	hindlimb nail position	females	0.0 %	1.0
SHIRPA	hindlimb nail position	males	0.0 %	1.0
SHIRPA	hindlimb nail position	both	0.0 %	1.0
SHIRPA	hindlimb nail shape	females	0.0 %	1.0
SHIRPA	hindlimb nail shape	males	0.0 %	1.0
SHIRPA	hindlimb nail shape	both	0.0 %	1.0
SHIRPA	hindlimbs footpads	females	0.0 %	1.0
SHIRPA	hindlimbs footpads	males	0.0 %	1.0
SHIRPA	hindlimbs footpads	both	0.0 %	1.0
SHIRPA	hindlimbs position	females	0.0 %	1.0
SHIRPA	hindlimbs position	males	0.0 %	1.0
SHIRPA	hindlimbs position	both	0.0 %	1.0
SHIRPA	hindlimbs shape	females	0.0 %	1.0
SHIRPA	hindlimbs shape	males	0.0 %	1.0
SHIRPA	hindlimbs shape	both	0.0 %	1.0
SHIRPA	hindlimbs size	females	0.0 %	1.0
SHIRPA	hindlimbs size	males	0.0 %	1.0
SHIRPA	hindlimbs size	both	0.0 %	1.0
SHIRPA	hindpaw position	females	0.0 %	1.0
SHIRPA	hindpaw position	males	0.0 %	1.0
SHIRPA	hindpaw position	both	0.0 %	1.0
SHIRPA	hindpaw shape	females	0.0 %	1.0
SHIRPA	hindpaw shape	males	0.0 %	1.0
SHIRPA	hindpaw shape	both	0.0 %	1.0
SHIRPA	hindpaw size	females	0.0 %	1.0
SHIRPA	hindpaw size	males	0.0 %	1.0
SHIRPA	hindpaw size	both	0.0 %	1.0
SHIRPA	limb grasp	females	9.0 %	1.00
SHIRPA	limb grasp	males	6.0 %	1.0
SHIRPA	limb grasp	both	7.0 %	0.624
SHIRPA	lower lip morphology	females	0.0 %	1.0
SHIRPA	lower lip morphology	males	0.0 %	1.0
SHIRPA	lower lip morphology	both	0.0 %	1.0
SHIRPA	lower teeth appearance	females	0.0 %	1.0
SHIRPA	lower teeth appearance	males	0.0 %	1.00
SHIRPA	lower teeth appearance	both	0.0 %	1.00
SHIRPA	mouth morphology	females	0.0 %	1.0
SHIRPA	mouth morphology	males	0.0 %	1.00
SHIRPA	mouth morphology	both	0.0 %	1.00
SHIRPA	salivation	females	0.0 %	1.0
SHIRPA	salivation	males	0.0 %	1.0
SHIRPA	salivation	both	0.0 %	1.0
SHIRPA	skin color back paws	females	0.0 %	1.0
SHIRPA	skin color back paws	males	0.0 %	1.0
SHIRPA	skin color back paws	both	0.0 %	1.0
SHIRPA	skin color ear	females	0.0 %	1.0
SHIRPA	skin color ear	males	0.0 %	1.0
SHIRPA	skin color ear	both	0.0 %	1.0
SHIRPA	skin color front paws	females	0.0 %	1.0
SHIRPA	skin color front paws	males	0.0 %	1.0
SHIRPA	skin color front paws	both	0.0 %	1.0
SHIRPA	skin color snout	females	0.0 %	1.0
SHIRPA	skin color snout	males	0.0 %	1.0
SHIRPA	skin color snout	both	0.0 %	1.0
SHIRPA	skin color tail	females	0.0 %	1.0
SHIRPA	skin color tail	males	0.0 %	1.0
SHIRPA	skin color tail	both	0.0 %	1.0
SHIRPA	skin color whole body	females	0.0 %	1.0
SHIRPA	skin color whole body	males	0.0 %	1.0
SHIRPA	skin color whole body	both	0.0 %	1.0
SHIRPA	skin texture back paw	females	0.0 %	1.0
SHIRPA	skin texture back paw	males	0.0 %	1.0
SHIRPA	skin texture back paw	both	0.0 %	1.0
SHIRPA	skin texture ear	females	0.0 %	1.0
SHIRPA	skin texture ear	males	0.0 %	1.0
SHIRPA	skin texture ear	both	0.0 %	1.0
SHIRPA	skin texture front paws	females	0.0 %	1.0
SHIRPA	skin texture front paws	males	0.0 %	1.0
SHIRPA	skin texture front paws	both	0.0 %	1.0
SHIRPA	skin texture snout	females	0.0 %	1.0
SHIRPA	skin texture snout	males	0.0 %	1.0
SHIRPA	skin texture snout	both	0.0 %	1.0
SHIRPA	skin texture tail	females	0.0 %	1.0
SHIRPA	skin texture tail	males	0.0 %	1.0
SHIRPA	skin texture tail	both	0.0 %	1.0
SHIRPA	skin texture whole body	females	0.0 %	1.0
SHIRPA	skin texture whole body	males	0.0 %	1.00
SHIRPA	skin texture whole body	both	0.0 %	1.00
SHIRPA	snout size	females	0.0 %	1.0
SHIRPA	snout size	males	1.0 %	1.0
SHIRPA	snout size	both	0.0 %	1.0
SHIRPA	startle response	females	0.0 %	1.00
SHIRPA	startle response	males	0.0 %	1.00
SHIRPA	startle response	both	0.0 %	1.00
SHIRPA	tail curvature	females	0.0 %	1.00
SHIRPA	tail curvature	males	0.0 %	1.0
SHIRPA	tail curvature	both	0.0 %	1.0
SHIRPA	tail elevation	females	1.0 %	1.00
SHIRPA	tail elevation	males	2.0 %	1.0
SHIRPA	tail elevation	both	1.0 %	1.0
SHIRPA	tail length	females	0.0 %	1.0
SHIRPA	tail length	males	0.0 %	1.0
SHIRPA	tail length	both	0.0 %	1.00
SHIRPA	tail morphology	females	0.0 %	1.00
SHIRPA	tail morphology	males	0.0 %	1.0
SHIRPA	tail morphology	both	0.0 %	1.00
SHIRPA	tail presence	females	0.0 %	1.0
SHIRPA	tail presence	males	0.0 %	1.0
SHIRPA	tail presence	both	0.0 %	1.0
SHIRPA	tail shape	females	0.0 %	1.0
SHIRPA	tail shape	males	0.0 %	1.0
SHIRPA	tail shape	both	0.0 %	1.00
SHIRPA	tail thickness	females	0.0 %	1.0
SHIRPA	tail thickness	males	0.0 %	1.0
SHIRPA	tail thickness	both	0.0 %	1.0
SHIRPA	teeth presence	females	0.0 %	1.0
SHIRPA	teeth presence	males	0.0 %	1.00
SHIRPA	teeth presence	both	0.0 %	1.00
SHIRPA	transfer arousal	females	1.0 %	1.0
SHIRPA	transfer arousal	males	2.0 %	1.00
SHIRPA	transfer arousal	both	1.0 %	1.0
SHIRPA	tremor	females	0.0 %	1.0
SHIRPA	tremor	males	0.0 %	1.0
SHIRPA	tremor	both	0.0 %	1.00
SHIRPA	trunk curl	females	0.0 %	1.00
SHIRPA	trunk curl	males	0.0 %	1.0
SHIRPA	trunk curl	both	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	females	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	males	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	both	0.0 %	1.00
SHIRPA	upper lip morphology	females	0.0 %	1.0
SHIRPA	upper lip morphology	males	0.0 %	1.0
SHIRPA	upper lip morphology	both	0.0 %	1.0
SHIRPA	upper teeth appearance	females	0.0 %	1.0
SHIRPA	upper teeth appearance	males	0.0 %	1.0
SHIRPA	upper teeth appearance	both	0.0 %	1.00
SHIRPA	vibrissae appearance	females	2.0 %	1.0
SHIRPA	vibrissae appearance	males	1.0 %	1.0
SHIRPA	vibrissae appearance	both	1.0 %	1.0
SHIRPA	vibrissae presence	females	2.0 %	1.00
SHIRPA	vibrissae presence	males	1.0 %	1.0
SHIRPA	vibrissae presence	both	2.0 %	1.0
SHIRPA	vocalization	females	2.0 %	1.00
SHIRPA	vocalization	males	98.0 %	0.00000802
SHIRPA	vocalization	both	31.0 %	0.000572

GENOTYPE CORRELATION PLOT

Correlate Dync1li2^em1(IMPC)J/Mmjax -/+ with genotype: