MPD: JaxKOMP-EAP genotype: 2610507B11Rik<sup>em1(IMPC)J</sup>/Mmjax -/+

JaxKOMP-EAP effect sizes: 2610507B11Rik^em1(IMPC)J/Mmjax -/+ Gene 2610507B11Rik

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value
body composition	body length	0.13083	0.056974	1.7078	0.182	0.0339
body composition	body weight (at time of DXA)	-0.058138	0.91726	0.040264	0.981	0.950
body composition	bone area, whole body scan, head excluded	0.24831	0.23932	1.2711	0.577	0.313
body composition	bone mineral content of whole body scan, head excluded	0.0080017	0.014506	0.59271	0.803	0.588
body composition	bone mineral content to body weight ratio	-0.00051644	0.00044746	-0.48378	0.540	0.264
body composition	bone mineral density of whole body scan, head excluded	-0.0011827	0.00074227	-1.2261	0.388	0.128
body composition	fat tissue mass of whole body scan, head excluded	0.29497	0.47494	0.48685	0.759	0.542
body composition	fat tissue mass to body weight ratio	0.0060052	0.015586	0.33809	0.857	0.705
body composition	lean tissue mass of whole body scan, head excluded	1.1803	0.59204	1.8895	0.283	0.0616
body composition	lean tissue mass to body weight ratio	0.013628	0.014686	0.68784	0.617	0.366
body composition	percent fat, whole body scan, head excluded	0.24819	1.4828	0.21043	0.940	0.869
body composition	ratio of soft-tissue attenuation coefficients	-0.00027585	0.0016482	-0.21649	0.946	0.869
body composition	tissue area	0.96977	0.30558	2.4260	0.0648	0.00526
body composition	total tissue mass, whole body scan, head excluded	1.2305	0.38664	2.0506	0.0453	0.00516
clinical blood chemistry	alanine transaminase (plasma ALT)	-0.51231	2.0949	-0.060258	0.944	0.809
clinical blood chemistry	albumin (plasma Alb)	-0.17735	0.35238	-0.21699	0.853	0.621
clinical blood chemistry	alkaline phosphatase (plasma ALP)	14.600	5.1207	1.5946	0.0717	0.0102
clinical blood chemistry	aspartate transaminase (plasma AST)	-7.5481	2.6778	-0.37891	0.130	0.0110
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	-0.24963	0.14685	-0.78279	0.480	0.105
clinical blood chemistry	blood urea nitrogen (BUN)	0.086834	1.8404	-0.012182	0.981	0.963
clinical blood chemistry	calcium (plasma Ca)	0.015179	0.067489	0.45057	0.907	0.824
clinical blood chemistry	creatinine (plasma)	-0.0070881	0.017907	-0.060302	0.833	0.696
clinical blood chemistry	glucose (plasma GLU, no fast)	-3.3642	13.971	0.16283	0.898	0.812
clinical blood chemistry	HDL cholesterol (plasma HDL)	5.4982	3.4924	0.94467	0.397	0.131
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	0.024343	0.013631	1.1646	0.379	0.0901
clinical blood chemistry	phosphorus (plasma phosphate)	-0.44948	0.33635	-0.76641	0.475	0.196
clinical blood chemistry	total bilirubin (plasma TBIL)	-0.0070574	0.0086780	-0.54372	0.756	0.426
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	5.8393	4.3954	0.75291	0.501	0.199
clinical blood chemistry	total protein (plasma TP)	0.53219	0.87508	0.32089	0.762	0.550
clinical blood chemistry	triglyceride (plasma TG, no fast)	7.9621	9.6859	0.65486	0.690	0.421
EKG	duration of PQ interval	-1.4476	1.0822	-1.2880	0.829	0.313
EKG	duration of PR interval	-1.2273	1.0533	-1.0524	0.877	0.364
EKG	duration of QRS interval	0.18926	0.65449	0.36457	0.979	0.800
EKG	duration of QT interval	-0.018569	0.71723	0.13745	0.998	0.982
EKG	duration of QTC interval, calculated by dividing QT interval by square root of preceding RR interval	0.23618	0.70989	0.31758	0.979	0.771
EKG	duration of RR interval	-0.91272	1.1961	-0.21318	0.833	0.525
EKG	duration of ST interval	-0.30021	0.68941	-0.088775	0.947	0.706
EKG	heart rate coefficient of variation (signal intensity)	2.0820	2.0109	1.6952	0.867	0.409
EKG	heart rate variability, mean of differences between sequential beats; beats per min	16.261	14.747	1.7869	0.867	0.385
EKG	heart rate, beats per min	9.7939	10.335	0.34020	0.782	0.443
EKG	mean R amplitude, mean amplitude of signal measured from isoelectric line to peak of QRS	-0.024228	0.15145	-0.31678	0.972	0.888
EKG	mean SR amplitude, mean amplitude of signal measured from signal minimum line to peak of QRS	0.00038777	0.27466	-0.073672	0.999	0.999
EKG	number of signals	-14.627	21.796	-2.0860	0.883	0.571
EKG	proportion of number pairs of successive beat-to-beat intervals that exceed 50 ms	4.7630	9.2911	0.95558	0.927	0.659
EKG	QT dispersion, measured as inter-lead variability of QT intervals	3.5691	4.7111	1.0079	0.955	0.528
EKG	QTc dispersion, calculated as rate-corrected QT dispersion	4.6263	5.0721	1.1484	0.929	0.458
EKG	root mean square of successive differences of neighboring RR intervals	2.3028	1.6167	1.2258	0.843	0.290
glucose tolerance test	amount glucose injected	4.8429	4.4188	1.5338	0.741	0.387
glucose tolerance test	plasma glucose, 0min	-4.9743	13.856	-0.70849	0.876	0.754
glucose tolerance test	plasma glucose, 15min	-11.683	63.680	-0.22425	0.954	0.871
glucose tolerance test	plasma glucose, 30min	-27.735	63.990	-0.74062	0.883	0.707
glucose tolerance test	plasma glucose, 60min	-31.132	62.942	-1.1808	0.880	0.670
glucose tolerance test	plasma glucose, 120min	-3.8782	29.324	-0.41073	0.961	0.907
grip strength	body weight (at time of grip strength test)	0.55751	0.55713	0.74351	0.516	0.325
grip strength	forelimb and hindlimb grip strength (mean of trials), average	-9.1170	6.2180	-0.41379	0.334	0.153
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	-0.40127	0.28201	-0.38079	0.350	0.165
grip strength	forelimb and hindlimb grip strength by trial, trial1	-7.6049	8.5196	-0.27953	0.672	0.379
grip strength	forelimb and hindlimb grip strength by trial, trial2	-10.345	6.6453	-0.41063	0.351	0.130
grip strength	forelimb and hindlimb grip strength by trial, trial3	-7.5223	7.2013	-0.28255	0.572	0.305
grip strength	forelimb grip strength (mean of trials), average	-4.6322	2.9954	-0.32514	0.359	0.132
grip strength	forelimb grip strength (mean of trials), average normalized to bw	-0.27931	0.14521	-0.47146	0.246	0.0639
grip strength	forelimb grip strength by trial, trial1	-2.8322	4.0223	-0.055215	0.789	0.487
grip strength	forelimb grip strength by trial, trial2	-6.5751	4.4021	-0.50253	0.449	0.145
grip strength	forelimb grip strength by trial, trial3	-4.8000	4.9428	-0.28860	0.667	0.339
heart weight	heart weight, normalized to body weight	0.47328	0.14173	1.0324	0.0312	0.00365
heart weight	heart weight, weight	11.496	4.5107	1.1041	0.106	0.0208
hematology	basophil differential (percent of total WBC)	0.094643	0.046621	1.2408	0.413	0.0559
hematology	calculated hemoglobin (cHGB)	0.066071	0.39175	-0.092261	0.948	0.868
hematology	eosinophil differential (percent of total WBC)	0.075984	0.33497	0.29767	0.946	0.823
hematology	hematocrit (HCT)	0.80888	1.1476	0.55476	0.719	0.489
hematology	hemoglobin concentration distribution width (HDW)	0.0074100	0.076775	0.21013	0.960	0.924
hematology	large unstained cells (percent of total WBC)	0.042857	0.095799	0.29520	0.861	0.659
hematology	lymphocyte differential (percent of total WBC)	3.1424	2.7436	1.0461	0.522	0.266
hematology	mean corpuscular hemoglobin (CHr)	0.071477	0.11089	0.59871	0.744	0.527
hematology	mean platelet volume (MPV)	0.11837	0.090784	0.58050	0.421	0.207
hematology	mean RBC corpuscular hemoglobin (MCH)	-0.092857	0.23750	-0.37904	0.871	0.700
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	-0.044643	0.64372	-0.096029	0.979	0.945
hematology	mean RBC corpuscular volume (MCV)	-0.47427	1.1900	-0.85691	0.847	0.695
hematology	measured hemoglobin (mHGB)	-0.065129	0.40670	-0.40387	0.947	0.874
hematology	monocyte differential (percent of total WBC)	-0.15714	0.22795	-0.31110	0.785	0.499
hematology	neutrophil differential (percent of total WBC)	-2.9089	2.4971	-1.1405	0.509	0.258
hematology	platelet count (PLT; units per volume x 10³)	44.919	45.839	0.65150	0.683	0.339
hematology	RBC corpuscular distribution width (RDW)	1.1643	1.0761	2.1085	0.560	0.292
hematology	RBC corpuscular hemoglobin concentration mean (CHCM)	0.0064521	0.28260	-0.0034814	0.990	0.982
hematology	red blood cell count (RBC; per volume x 10⁶)	-0.12500	0.35506	-0.83269	0.876	0.728
hematology	reticulocyte count (Retic; units per volume x 10⁹)	-166.50	223.88	-3.0629	0.794	0.466
hematology	reticulocyte differential (percent of total RBC)	-2.2372	3.3924	-3.0372	0.793	0.518
hematology	white blood cell count (WBC; units per volume x 10³)	-0.0076574	1.0062	0.18696	0.997	0.994
holeboard	number of hole pokes by individual hole number, 20 min test, 1	-0.22740	0.76320	-0.17389	0.942	0.768
holeboard	number of hole pokes by individual hole number, 20 min test, 2	0.37500	0.73797	0.72462	0.901	0.615
holeboard	number of hole pokes by individual hole number, 20 min test, 3	-0.012500	0.56875	0.076878	0.993	0.983
holeboard	number of hole pokes by individual hole number, 20 min test, 4	0.25596	0.68270	0.32731	0.914	0.710
holeboard	number of hole pokes by individual hole number, 20 min test, 5	0.075000	0.51715	0.22902	0.970	0.886
holeboard	number of hole pokes by individual hole number, 20 min test, 6	1.0285	0.60326	1.9853	0.681	0.0979
holeboard	number of hole pokes by individual hole number, 20 min test, 7	0.15496	0.39892	0.42949	0.971	0.700
holeboard	number of hole pokes by individual hole number, 20 min test, 8	0.21250	0.43969	0.48130	0.924	0.632
holeboard	number of hole pokes by individual hole number, 20 min test, 9	-0.54273	0.47697	-0.87284	0.743	0.264
holeboard	number of hole pokes by individual hole number, 20 min test, 10	0.26747	0.43509	0.74076	0.910	0.543
holeboard	number of hole pokes by individual hole number, 20 min test, 11	0.21190	0.35288	0.55016	0.899	0.553
holeboard	number of hole pokes by individual hole number, 20 min test, 12	0.53750	0.58884	0.95582	0.786	0.368
holeboard	number of hole pokes by individual hole number, 20 min test, 13	-0.68750	0.78243	-0.58500	0.750	0.386
holeboard	number of hole pokes by individual hole number, 20 min test, 14	0.89983	0.61032	1.3955	0.581	0.150
holeboard	number of hole pokes by individual hole number, 20 min test, 15	0.19298	0.42156	0.36199	0.902	0.650
holeboard	number of hole pokes by individual hole number, 20 min test, 16	0.025000	0.82387	0.043872	0.990	0.976
holeboard	total number of hole pokes, 20 min test	2.0875	4.6491	0.38550	0.831	0.656
light / dark	latency to enter dark zone, 20 min test	44.341	56.606	0.67364	0.805	0.440
light / dark	number of transitions between light and dark zones, 20 min test	-29.765	10.447	-2.3587	0.105	0.00813
light / dark	percentage of total time in dark zone, 20 min test	3.4661	5.4631	0.72897	0.802	0.531
light / dark	percentage of total time in light zone, 20 min test	-3.4661	5.4631	-0.73074	0.800	0.531
light / dark	time mobile in dark zone, 20 min test	-42.364	13.329	-2.1534	0.0479	0.00360
light / dark	time mobile in light zone, 20 min test	-29.839	18.613	-2.0775	0.341	0.120
light / dark	time spent in dark zone, 20 min test	9.5286	75.253	0.36054	0.965	0.900
light / dark	time spent in light zone, 20 min test	-9.5286	75.253	-0.36054	0.965	0.900
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	-3.7020	1.4061	-1.3375	0.129	0.0133
startle / PPI	average baseline movement during background noise	1.0833	1.9021	0.75267	0.911	0.573
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	0.19691	0.054566	1.5852	0.0637	0.00111
startle / PPI	average of each corrected percent pre-pulse inhibition value	0.19889	0.058184	1.7874	0.0655	0.00183
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	7.3430	7.5053	0.85326	0.879	0.335
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	20.499	5.6805	2.0870	0.0911	0.00111
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	21.181	4.6227	2.0870	0.00718	0.0000756
startle / PPI	average startle response to full pulse (120 dB)	-112.16	38.674	-1.5706	0.0498	0.00680
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-115.95	36.829	-1.5803	0.0304	0.00362
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-127.27	39.471	-1.9206	0.0259	0.00297
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-111.09	32.376	-2.0628	0.0200	0.00172
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	0.56250	1.8474	0.44977	0.964	0.763
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	2.2416	1.6122	1.1548	0.692	0.174
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	4.5958	1.6057	1.4936	0.186	0.00747
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.050103	0.087468	0.52071	0.922	0.571
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.23423	0.063900	1.8459	0.0637	0.000949
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.27925	0.058046	1.8539	0.00275	0.0000369
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	-113.62	38.762	-1.5706	0.0471	0.00629
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	-117.51	37.165	-1.6002	0.0291	0.00349
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	-129.46	39.624	-1.9206	0.0235	0.00266
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	-115.11	32.709	-2.1256	0.0168	0.00136
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.078546	0.087655	0.71778	0.860	0.377
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.22311	0.060470	1.6692	0.0600	0.000889
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.27746	0.057410	1.6922	0.00269	0.0000346
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	-456.42	143.37	-1.7043	0.0295	0.00330
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	-470.95	132.20	-1.8020	0.0139	0.00121
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	-498.85	136.66	-2.0628	0.0119	0.000955
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	-444.85	118.93	-2.1980	0.0117	0.000748
startle / PPI	maximum baseline movement during background noise	1.9000	4.4669	0.61794	0.934	0.674
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	9.3525	7.7575	0.95445	0.884	0.237
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	21.241	5.3347	1.9118	0.0502	0.000402
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	22.329	4.7984	1.9387	0.00531	0.0000619
startle / PPI	maximum startle response to full pulse (120 dB)	-453.95	142.82	-1.7104	0.0299	0.00335
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-466.55	131.68	-1.7811	0.0145	0.00128
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-494.48	136.23	-2.0288	0.0123	0.00101
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-433.60	118.28	-2.1677	0.0136	0.000916
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	1.7917	4.5737	0.61456	0.937	0.698
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	4.5510	3.3445	1.0941	0.696	0.183
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	12.518	4.5036	1.5706	0.173	0.00917

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Sex	Trait Effect	P-value
eye morphology	anterior chamber depth	females	1.0 %	1.0
eye morphology	anterior chamber depth	males	0.0 %	1.0
eye morphology	anterior chamber depth	both	1.0 %	1.0
eye morphology	bulging eye	females	1.0 %	1.0
eye morphology	bulging eye	males	0.0 %	1.0
eye morphology	bulging eye	both	1.0 %	1.00
eye morphology	cornea	females	12.0 %	0.175
eye morphology	cornea	males	36.0 %	0.0000462
eye morphology	cornea	both	22.0 %	0.000159
eye morphology	cornea opacity	females	9.0 %	0.359
eye morphology	cornea opacity	males	1.0 %	1.0
eye morphology	cornea opacity	both	4.0 %	0.428
eye morphology	cornea vascularization	females	12.0 %	0.189
eye morphology	cornea vascularization	males	1.0 %	1.0
eye morphology	cornea vascularization	both	6.0 %	0.234
eye morphology	corneal deposits	females	2.0 %	1.0
eye morphology	corneal deposits	males	1.0 %	1.0
eye morphology	corneal deposits	both	1.0 %	1.00
eye morphology	corneal mineralization	females	2.0 %	1.0
eye morphology	corneal mineralization	males	1.0 %	1.0
eye morphology	corneal mineralization	both	1.0 %	1.00
eye morphology	corneal scleralization	females	11.0 %	0.220
eye morphology	corneal scleralization	males	1.0 %	1.0
eye morphology	corneal scleralization	both	5.0 %	0.292
eye morphology	corneal ulcer	females	1.0 %	1.0
eye morphology	corneal ulcer	males	1.0 %	1.0
eye morphology	corneal ulcer	both	1.0 %	1.00
eye morphology	eye closure	females	1.0 %	1.00
eye morphology	eye closure	males	0.0 %	1.0
eye morphology	eye closure	both	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	females	2.0 %	1.00
eye morphology	eye hemorrhage or blood presence	males	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	both	1.0 %	1.00
eye morphology	eyelid morphology	females	1.0 %	1.0
eye morphology	eyelid morphology	males	0.0 %	1.0
eye morphology	eyelid morphology	both	1.0 %	1.0
eye morphology	eyes (present, absent)	females	1.0 %	1.0
eye morphology	eyes (present, absent)	males	0.0 %	1.0
eye morphology	eyes (present, absent)	both	0.0 %	1.0
eye morphology	fusion between cornea and lens	females	4.0 %	1.00
eye morphology	fusion between cornea and lens	males	2.0 %	1.0
eye morphology	fusion between cornea and lens	both	3.0 %	1.00
eye morphology	iris pigmentation	females	2.0 %	1.0
eye morphology	iris pigmentation	males	1.0 %	1.0
eye morphology	iris pigmentation	both	2.0 %	1.00
eye morphology	iris transillumination	females	2.0 %	1.00
eye morphology	iris transillumination	males	1.0 %	1.0
eye morphology	iris transillumination	both	1.0 %	1.00
eye morphology	irispupil	females	4.0 %	1.00
eye morphology	irispupil	males	3.0 %	1.0
eye morphology	irispupil	both	3.0 %	1.00
eye morphology	lacrimation	females	3.0 %	1.0
eye morphology	lacrimation	males	2.0 %	1.0
eye morphology	lacrimation	both	3.0 %	1.0
eye morphology	lens	females	10.0 %	1.00
eye morphology	lens	males	8.0 %	1.0
eye morphology	lens	both	9.0 %	1.0
eye morphology	lens opacity	females	9.0 %	1.0
eye morphology	lens opacity	males	6.0 %	1.0
eye morphology	lens opacity	both	7.0 %	1.00
eye morphology	narrow eye opening	females	2.0 %	1.0
eye morphology	narrow eye opening	males	1.0 %	1.0
eye morphology	narrow eye opening	both	1.0 %	1.0
eye morphology	optic disc	females	4.0 %	1.00
eye morphology	optic disc	males	2.0 %	1.0
eye morphology	optic disc	both	3.0 %	1.00
eye morphology	persistence of hyaloid vascular system	females	6.0 %	0.690
eye morphology	persistence of hyaloid vascular system	males	5.0 %	1.0
eye morphology	persistence of hyaloid vascular system	both	3.0 %	0.790
eye morphology	pupil dilation	females	2.0 %	1.0
eye morphology	pupil dilation	males	1.0 %	1.0
eye morphology	pupil dilation	both	2.0 %	1.0
eye morphology	pupil light response	females	2.0 %	1.00
eye morphology	pupil light response	males	1.0 %	1.0
eye morphology	pupil light response	both	2.0 %	1.00
eye morphology	pupil position	females	4.0 %	1.00
eye morphology	pupil position	males	3.0 %	1.0
eye morphology	pupil position	both	4.0 %	1.00
eye morphology	pupil shape	females	3.0 %	1.00
eye morphology	pupil shape	males	2.0 %	1.0
eye morphology	pupil shape	both	3.0 %	1.00
eye morphology	retina	females	10.0 %	0.457
eye morphology	retina	males	16.0 %	1.0
eye morphology	retina	both	7.0 %	0.801
eye morphology	retinal blood vessels	females	4.0 %	1.0
eye morphology	retinal blood vessels	males	2.0 %	1.0
eye morphology	retinal blood vessels	both	3.0 %	1.0
eye morphology	retinal blood vessels pattern	females	5.0 %	1.0
eye morphology	retinal blood vessels pattern	males	2.0 %	1.0
eye morphology	retinal blood vessels pattern	both	4.0 %	1.00
eye morphology	retinal blood vessels structure	females	4.0 %	1.00
eye morphology	retinal blood vessels structure	males	2.0 %	1.0
eye morphology	retinal blood vessels structure	both	3.0 %	1.00
eye morphology	retinal pigmentation	females	12.0 %	1.0
eye morphology	retinal pigmentation	males	14.0 %	1.0
eye morphology	retinal pigmentation	both	13.0 %	1.0
eye morphology	retinal structure	females	4.0 %	1.00
eye morphology	retinal structure	males	2.0 %	1.0
eye morphology	retinal structure	both	3.0 %	1.00
eye morphology	synechia	females	4.0 %	1.0
eye morphology	synechia	males	2.0 %	1.0
eye morphology	synechia	both	3.0 %	1.00
eye morphology	vitreous	females	4.0 %	1.00
eye morphology	vitreous	males	2.0 %	1.0
eye morphology	vitreous	both	3.0 %	1.00
SHIRPA	activity body position	females	87.0 %	2.02e-15
SHIRPA	activity body position	males	37.0 %	0.0000335
SHIRPA	activity body position	both	62.0 %	1.15e-17
SHIRPA	aggression	females	0.0 %	1.00
SHIRPA	aggression	males	1.0 %	1.0
SHIRPA	aggression	both	1.0 %	1.0
SHIRPA	body length	females	0.0 %	1.0
SHIRPA	body length	males	0.0 %	1.00
SHIRPA	body length	both	0.0 %	1.00
SHIRPA	body position	females	87.0 %	2.89e-17
SHIRPA	body position	males	37.0 %	0.0000161
SHIRPA	body position	both	62.0 %	5.73e-20
SHIRPA	body thickness	females	12.0 %	0.0517
SHIRPA	body thickness	males	0.0 %	1.0
SHIRPA	body thickness	both	6.0 %	0.0796
SHIRPA	coat color abdomen	females	97.0 %	3.20e-12
SHIRPA	coat color abdomen	males	96.0 %	4.02e-12
SHIRPA	coat color abdomen	both	96.0 %	1.24e-23
SHIRPA	coat color back	females	0.0 %	1.0
SHIRPA	coat color back	males	0.0 %	1.00
SHIRPA	coat color back	both	0.0 %	1.00
SHIRPA	coat color head	females	0.0 %	1.0
SHIRPA	coat color head	males	0.0 %	1.00
SHIRPA	coat color head	both	0.0 %	1.0
SHIRPA	coat color pattern abdomen	females	1.0 %	1.0
SHIRPA	coat color pattern abdomen	males	1.0 %	1.0
SHIRPA	coat color pattern abdomen	both	1.0 %	1.0
SHIRPA	coat color pattern back	females	0.0 %	1.0
SHIRPA	coat color pattern back	males	0.0 %	1.00
SHIRPA	coat color pattern back	both	0.0 %	1.0
SHIRPA	coat color pattern head	females	0.0 %	1.0
SHIRPA	coat color pattern head	males	0.0 %	1.0
SHIRPA	coat color pattern head	both	0.0 %	1.00
SHIRPA	coat hair abdomen texture appearance	females	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	males	23.0 %	0.0279
SHIRPA	coat hair abdomen texture appearance	both	11.0 %	0.0618
SHIRPA	coat hair back texture appearance	females	0.0 %	1.0
SHIRPA	coat hair back texture appearance	males	12.0 %	0.0322
SHIRPA	coat hair back texture appearance	both	6.0 %	0.0575
SHIRPA	coat hair distribution abdomen	females	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	males	24.0 %	0.00365
SHIRPA	coat hair distribution abdomen	both	12.0 %	0.00512
SHIRPA	coat hair distribution back	females	0.0 %	1.0
SHIRPA	coat hair distribution back	males	12.0 %	0.0206
SHIRPA	coat hair distribution back	both	6.0 %	0.0349
SHIRPA	coat hair distribution head	females	1.0 %	1.00
SHIRPA	coat hair distribution head	males	1.0 %	1.0
SHIRPA	coat hair distribution head	both	1.0 %	1.0
SHIRPA	coat hair head texture appearance	females	0.0 %	1.00
SHIRPA	coat hair head texture appearance	males	0.0 %	1.0
SHIRPA	coat hair head texture appearance	both	0.0 %	1.0
SHIRPA	contact righting	females	5.0 %	1.0
SHIRPA	contact righting	males	5.0 %	1.00
SHIRPA	contact righting	both	5.0 %	1.00
SHIRPA	ear morphology	females	0.0 %	1.0
SHIRPA	ear morphology	males	0.0 %	1.0
SHIRPA	ear morphology	both	0.0 %	1.0
SHIRPA	fat distribution	females	0.0 %	1.0
SHIRPA	fat distribution	males	0.0 %	1.0
SHIRPA	fat distribution	both	0.0 %	1.00
SHIRPA	forelimb digit number	females	0.0 %	1.00
SHIRPA	forelimb digit number	males	0.0 %	1.0
SHIRPA	forelimb digit number	both	0.0 %	1.00
SHIRPA	forelimb digit position	females	0.0 %	1.0
SHIRPA	forelimb digit position	males	0.0 %	1.0
SHIRPA	forelimb digit position	both	0.0 %	1.0
SHIRPA	forelimb digit shape	females	0.0 %	1.0
SHIRPA	forelimb digit shape	males	0.0 %	1.0
SHIRPA	forelimb digit shape	both	0.0 %	1.0
SHIRPA	forelimb digit size	females	0.0 %	1.0
SHIRPA	forelimb digit size	males	0.0 %	1.0
SHIRPA	forelimb digit size	both	0.0 %	1.0
SHIRPA	forelimb footpads	females	0.0 %	1.0
SHIRPA	forelimb footpads	males	0.0 %	1.0
SHIRPA	forelimb footpads	both	0.0 %	1.0
SHIRPA	forelimb nail length	females	0.0 %	1.0
SHIRPA	forelimb nail length	males	0.0 %	1.0
SHIRPA	forelimb nail length	both	0.0 %	1.0
SHIRPA	forelimb nail number	females	0.0 %	1.0
SHIRPA	forelimb nail number	males	0.0 %	1.0
SHIRPA	forelimb nail number	both	0.0 %	1.0
SHIRPA	forelimb nail position	females	0.0 %	1.0
SHIRPA	forelimb nail position	males	0.0 %	1.0
SHIRPA	forelimb nail position	both	0.0 %	1.0
SHIRPA	forelimb nail shape	females	0.0 %	1.0
SHIRPA	forelimb nail shape	males	0.0 %	1.0
SHIRPA	forelimb nail shape	both	0.0 %	1.0
SHIRPA	forelimbs position	females	0.0 %	1.0
SHIRPA	forelimbs position	males	0.0 %	1.0
SHIRPA	forelimbs position	both	0.0 %	1.0
SHIRPA	forelimbs shape	females	0.0 %	1.0
SHIRPA	forelimbs shape	males	0.0 %	1.0
SHIRPA	forelimbs shape	both	0.0 %	1.0
SHIRPA	forelimbs size	females	0.0 %	1.0
SHIRPA	forelimbs size	males	0.0 %	1.0
SHIRPA	forelimbs size	both	0.0 %	1.0
SHIRPA	forepaw position	females	0.0 %	1.0
SHIRPA	forepaw position	males	0.0 %	1.0
SHIRPA	forepaw position	both	0.0 %	1.0
SHIRPA	forepaw shape	females	0.0 %	1.0
SHIRPA	forepaw shape	males	0.0 %	1.0
SHIRPA	forepaw shape	both	0.0 %	1.0
SHIRPA	forepaw size	females	0.0 %	1.0
SHIRPA	forepaw size	males	0.0 %	1.0
SHIRPA	forepaw size	both	0.0 %	1.0
SHIRPA	gait (fluidity)	females	0.0 %	1.0
SHIRPA	gait (fluidity)	males	0.0 %	1.00
SHIRPA	gait (fluidity)	both	0.0 %	1.00
SHIRPA	genitalia morphology	females	0.0 %	1.00
SHIRPA	genitalia morphology	males	0.0 %	1.0
SHIRPA	genitalia morphology	both	0.0 %	1.00
SHIRPA	genitalia presence	females	0.0 %	1.0
SHIRPA	genitalia presence	males	0.0 %	1.0
SHIRPA	genitalia presence	both	0.0 %	1.0
SHIRPA	genitalia size	females	0.0 %	1.0
SHIRPA	genitalia size	males	0.0 %	1.0
SHIRPA	genitalia size	both	0.0 %	1.0
SHIRPA	head bobbing	females	0.0 %	1.0
SHIRPA	head bobbing	males	12.0 %	0.00592
SHIRPA	head bobbing	both	6.0 %	0.00589
SHIRPA	head morphology	females	0.0 %	1.0
SHIRPA	head morphology	males	0.0 %	1.00
SHIRPA	head morphology	both	0.0 %	1.0
SHIRPA	head size	females	0.0 %	1.0
SHIRPA	head size	males	0.0 %	1.0
SHIRPA	head size	both	0.0 %	1.00
SHIRPA	hindlimb digit number	females	1.0 %	1.00
SHIRPA	hindlimb digit number	males	0.0 %	1.0
SHIRPA	hindlimb digit number	both	0.0 %	1.00
SHIRPA	hindlimb digit position	females	0.0 %	1.0
SHIRPA	hindlimb digit position	males	0.0 %	1.0
SHIRPA	hindlimb digit position	both	0.0 %	1.0
SHIRPA	hindlimb digit shape	females	0.0 %	1.0
SHIRPA	hindlimb digit shape	males	0.0 %	1.0
SHIRPA	hindlimb digit shape	both	0.0 %	1.0
SHIRPA	hindlimb digit size	females	0.0 %	1.00
SHIRPA	hindlimb digit size	males	0.0 %	1.0
SHIRPA	hindlimb digit size	both	0.0 %	1.00
SHIRPA	hindlimb nail length	females	0.0 %	1.0
SHIRPA	hindlimb nail length	males	0.0 %	1.0
SHIRPA	hindlimb nail length	both	0.0 %	1.00
SHIRPA	hindlimb nail number	females	0.0 %	1.0
SHIRPA	hindlimb nail number	males	1.0 %	1.0
SHIRPA	hindlimb nail number	both	0.0 %	1.00
SHIRPA	hindlimb nail position	females	0.0 %	1.0
SHIRPA	hindlimb nail position	males	0.0 %	1.0
SHIRPA	hindlimb nail position	both	0.0 %	1.0
SHIRPA	hindlimb nail shape	females	0.0 %	1.0
SHIRPA	hindlimb nail shape	males	0.0 %	1.0
SHIRPA	hindlimb nail shape	both	0.0 %	1.0
SHIRPA	hindlimbs footpads	females	0.0 %	1.0
SHIRPA	hindlimbs footpads	males	0.0 %	1.0
SHIRPA	hindlimbs footpads	both	0.0 %	1.0
SHIRPA	hindlimbs position	females	0.0 %	1.0
SHIRPA	hindlimbs position	males	0.0 %	1.0
SHIRPA	hindlimbs position	both	0.0 %	1.0
SHIRPA	hindlimbs shape	females	0.0 %	1.0
SHIRPA	hindlimbs shape	males	0.0 %	1.0
SHIRPA	hindlimbs shape	both	0.0 %	1.0
SHIRPA	hindlimbs size	females	0.0 %	1.0
SHIRPA	hindlimbs size	males	0.0 %	1.0
SHIRPA	hindlimbs size	both	0.0 %	1.0
SHIRPA	hindpaw position	females	0.0 %	1.0
SHIRPA	hindpaw position	males	0.0 %	1.0
SHIRPA	hindpaw position	both	0.0 %	1.0
SHIRPA	hindpaw shape	females	0.0 %	1.0
SHIRPA	hindpaw shape	males	12.0 %	0.00296
SHIRPA	hindpaw shape	both	6.0 %	0.00589
SHIRPA	hindpaw size	females	0.0 %	1.0
SHIRPA	hindpaw size	males	0.0 %	1.0
SHIRPA	hindpaw size	both	0.0 %	1.0
SHIRPA	limb grasp	females	9.0 %	1.00
SHIRPA	limb grasp	males	7.0 %	0.375
SHIRPA	limb grasp	both	1.0 %	1.0
SHIRPA	lower lip morphology	females	0.0 %	1.0
SHIRPA	lower lip morphology	males	0.0 %	1.0
SHIRPA	lower lip morphology	both	0.0 %	1.0
SHIRPA	lower teeth appearance	females	0.0 %	1.0
SHIRPA	lower teeth appearance	males	0.0 %	1.00
SHIRPA	lower teeth appearance	both	0.0 %	1.00
SHIRPA	mouth morphology	females	0.0 %	1.0
SHIRPA	mouth morphology	males	0.0 %	1.00
SHIRPA	mouth morphology	both	0.0 %	1.00
SHIRPA	salivation	females	0.0 %	1.0
SHIRPA	salivation	males	0.0 %	1.0
SHIRPA	salivation	both	0.0 %	1.0
SHIRPA	skin color back paws	females	0.0 %	1.0
SHIRPA	skin color back paws	males	0.0 %	1.0
SHIRPA	skin color back paws	both	0.0 %	1.0
SHIRPA	skin color ear	females	0.0 %	1.0
SHIRPA	skin color ear	males	0.0 %	1.0
SHIRPA	skin color ear	both	0.0 %	1.0
SHIRPA	skin color front paws	females	0.0 %	1.0
SHIRPA	skin color front paws	males	0.0 %	1.0
SHIRPA	skin color front paws	both	0.0 %	1.0
SHIRPA	skin color snout	females	0.0 %	1.0
SHIRPA	skin color snout	males	0.0 %	1.0
SHIRPA	skin color snout	both	0.0 %	1.0
SHIRPA	skin color tail	females	0.0 %	1.0
SHIRPA	skin color tail	males	0.0 %	1.0
SHIRPA	skin color tail	both	0.0 %	1.0
SHIRPA	skin color whole body	females	0.0 %	1.0
SHIRPA	skin color whole body	males	0.0 %	1.0
SHIRPA	skin color whole body	both	0.0 %	1.0
SHIRPA	skin texture back paw	females	0.0 %	1.0
SHIRPA	skin texture back paw	males	0.0 %	1.0
SHIRPA	skin texture back paw	both	0.0 %	1.0
SHIRPA	skin texture ear	females	0.0 %	1.0
SHIRPA	skin texture ear	males	0.0 %	1.0
SHIRPA	skin texture ear	both	0.0 %	1.0
SHIRPA	skin texture front paws	females	0.0 %	1.0
SHIRPA	skin texture front paws	males	0.0 %	1.0
SHIRPA	skin texture front paws	both	0.0 %	1.0
SHIRPA	skin texture snout	females	0.0 %	1.0
SHIRPA	skin texture snout	males	0.0 %	1.0
SHIRPA	skin texture snout	both	0.0 %	1.0
SHIRPA	skin texture tail	females	0.0 %	1.0
SHIRPA	skin texture tail	males	0.0 %	1.0
SHIRPA	skin texture tail	both	0.0 %	1.0
SHIRPA	skin texture whole body	females	0.0 %	1.0
SHIRPA	skin texture whole body	males	0.0 %	1.00
SHIRPA	skin texture whole body	both	0.0 %	1.00
SHIRPA	snout size	females	0.0 %	1.0
SHIRPA	snout size	males	1.0 %	1.0
SHIRPA	snout size	both	0.0 %	1.0
SHIRPA	startle response	females	0.0 %	1.00
SHIRPA	startle response	males	0.0 %	1.00
SHIRPA	startle response	both	0.0 %	1.00
SHIRPA	tail curvature	females	0.0 %	1.00
SHIRPA	tail curvature	males	0.0 %	1.0
SHIRPA	tail curvature	both	0.0 %	1.0
SHIRPA	tail elevation	females	1.0 %	1.00
SHIRPA	tail elevation	males	2.0 %	1.0
SHIRPA	tail elevation	both	1.0 %	1.0
SHIRPA	tail length	females	0.0 %	1.0
SHIRPA	tail length	males	0.0 %	1.0
SHIRPA	tail length	both	0.0 %	1.00
SHIRPA	tail morphology	females	0.0 %	1.00
SHIRPA	tail morphology	males	0.0 %	1.0
SHIRPA	tail morphology	both	0.0 %	1.00
SHIRPA	tail presence	females	0.0 %	1.0
SHIRPA	tail presence	males	0.0 %	1.0
SHIRPA	tail presence	both	0.0 %	1.0
SHIRPA	tail shape	females	0.0 %	1.0
SHIRPA	tail shape	males	0.0 %	1.0
SHIRPA	tail shape	both	0.0 %	1.00
SHIRPA	tail thickness	females	0.0 %	1.0
SHIRPA	tail thickness	males	0.0 %	1.0
SHIRPA	tail thickness	both	0.0 %	1.0
SHIRPA	teeth presence	females	12.0 %	0.00879
SHIRPA	teeth presence	males	0.0 %	1.00
SHIRPA	teeth presence	both	6.0 %	0.0147
SHIRPA	transfer arousal	females	86.0 %	7.10e-16
SHIRPA	transfer arousal	males	37.0 %	0.0000691
SHIRPA	transfer arousal	both	61.0 %	4.08e-19
SHIRPA	tremor	females	0.0 %	1.0
SHIRPA	tremor	males	0.0 %	1.0
SHIRPA	tremor	both	0.0 %	1.00
SHIRPA	trunk curl	females	0.0 %	1.00
SHIRPA	trunk curl	males	0.0 %	1.0
SHIRPA	trunk curl	both	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	females	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	males	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	both	0.0 %	1.00
SHIRPA	upper lip morphology	females	0.0 %	1.0
SHIRPA	upper lip morphology	males	0.0 %	1.0
SHIRPA	upper lip morphology	both	0.0 %	1.0
SHIRPA	upper teeth appearance	females	0.0 %	1.0
SHIRPA	upper teeth appearance	males	0.0 %	1.0
SHIRPA	upper teeth appearance	both	0.0 %	1.00
SHIRPA	vibrissae appearance	females	2.0 %	1.0
SHIRPA	vibrissae appearance	males	1.0 %	1.0
SHIRPA	vibrissae appearance	both	1.0 %	1.0
SHIRPA	vibrissae presence	females	35.0 %	0.000730
SHIRPA	vibrissae presence	males	1.0 %	1.0
SHIRPA	vibrissae presence	both	17.0 %	0.00192
SHIRPA	vocalization	females	2.0 %	1.00
SHIRPA	vocalization	males	2.0 %	1.0
SHIRPA	vocalization	both	2.0 %	1.0

GENOTYPE CORRELATION PLOT

Correlate 2610507B11Rik^em1(IMPC)J/Mmjax -/+ with genotype: