MPD: JaxKOMP-EAP genotype: Tesk1<sup>em1(IMPC)J</sup>/Mmjax -/-

JaxKOMP-EAP effect sizes: Tesk1^em1(IMPC)J/Mmjax -/- Gene Tesk1

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

In this plot, data points are the computed genotype effect size vs. C57BL/6NJ controls, for all measured numeric phenotypes in JaxKOMP-EAP

Dimensions Width: × Height: px

Plot Options Group by Procedure Standard Error Show Effect Sizes RankZ

Significance Threshold p-Value Threshold Adjusted Unadjusted

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Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value

ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	-3.3761	1.4973	-1.1687	0.308	0.0368
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	-1.6726	3.1296	-0.35067	0.885	0.600
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	-0.13903	2.2901	-0.20958	0.988	0.952
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	16.576	2.9927	2.0977	0.00363	0.0000294
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	9.3445	3.0011	1.4128	0.110	0.00600
body composition	body length	-0.045093	0.036218	-0.32207	0.523	0.224
body composition	body weight (at time of DXA)	-0.16521	0.66909	-0.034802	0.909	0.807
body composition	bone area, whole body scan, head excluded	-0.24974	0.14713	-0.80559	0.324	0.101
body composition	bone mineral content of whole body scan, head excluded	-0.016037	0.011802	-0.73041	0.461	0.185
body composition	bone mineral content to body weight ratio	-0.00068353	0.00047442	-0.70742	0.412	0.161
body composition	bone mineral density of whole body scan, head excluded	-0.00035376	0.00053860	-0.36225	0.761	0.517
body composition	fat tissue mass of whole body scan, head excluded	0.62223	0.29762	0.90808	0.200	0.0461
body composition	fat tissue mass to body weight ratio	0.020888	0.010408	0.92052	0.198	0.0549
body composition	lean tissue mass of whole body scan, head excluded	-0.55742	0.24507	-1.2235	0.191	0.0311
body composition	lean tissue mass to body weight ratio	-0.024119	0.0087939	-1.2925	0.0925	0.0107
body composition	percent fat, whole body scan, head excluded	2.1200	0.99969	0.99392	0.171	0.0433
body composition	ratio of soft-tissue attenuation coefficients	-0.0023556	0.0011116	-1.0037	0.174	0.0434
body composition	tissue area	0.33246	0.14734	1.1752	0.189	0.0324
body composition	total tissue mass, whole body scan, head excluded	0.051888	0.17075	-0.10257	0.877	0.764
clinical blood chemistry	alanine transaminase (plasma ALT)	26.780	27.572	1.3995	0.700	0.347
clinical blood chemistry	albumin (plasma Alb)	-0.11271	0.41043	-0.11001	0.925	0.788
clinical blood chemistry	alkaline phosphatase (plasma ALP)	6.6610	5.9340	0.65198	0.536	0.279
clinical blood chemistry	aspartate transaminase (plasma AST)	-21.531	20.585	-0.99418	0.633	0.313
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	-1.0129	0.30076	-2.1775	0.121	0.00423
clinical blood chemistry	blood urea nitrogen (BUN)	1.7203	2.5127	0.66597	0.733	0.504
clinical blood chemistry	calcium (plasma Ca)	0.050847	0.085007	0.70288	0.747	0.559
clinical blood chemistry	creatinine (plasma)	-0.033400	0.017403	-0.64089	0.255	0.0756
clinical blood chemistry	glucose (plasma GLU, no fast)	11.898	15.307	0.75138	0.651	0.449
clinical blood chemistry	HDL cholesterol (plasma HDL)	2.9294	2.9365	0.38555	0.634	0.335
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	-0.037729	0.0095099	-2.0222	0.0356	0.00124
clinical blood chemistry	phosphorus (plasma phosphate)	0.072590	0.71346	0.066312	0.973	0.920
clinical blood chemistry	total bilirubin (plasma TBIL)	-0.0048754	0.0063068	-0.38547	0.764	0.452
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	6.7997	3.3603	0.89044	0.270	0.0625
clinical blood chemistry	total protein (plasma TP)	-0.36165	0.42150	-0.35262	0.653	0.404
clinical blood chemistry	triglyceride (plasma TG, no fast)	49.386	9.5700	2.0662	0.0202	0.000145
EKG	duration of PQ interval	0.80716	0.71906	1.0079	0.805	0.270
EKG	duration of PR interval	0.82972	0.70423	0.98146	0.807	0.247
EKG	duration of QRS interval	-0.036140	0.21347	-0.23798	0.988	0.867
EKG	duration of QT interval	-1.3032	1.0082	-1.0351	0.694	0.205
EKG	duration of QTC interval, calculated by dividing QT interval by square root of preceding RR interval	-1.3066	0.93799	-1.3114	0.739	0.173
EKG	duration of RR interval	-0.63728	1.0630	-0.050396	0.840	0.553
EKG	duration of ST interval	-1.2125	1.0353	-0.94935	0.744	0.250
EKG	heart rate coefficient of variation (signal intensity)	-0.59875	0.68987	-0.39053	0.867	0.392
EKG	heart rate variability, mean of differences between sequential beats; beats per min	-4.3909	4.9452	-0.44107	0.866	0.381
EKG	heart rate, beats per min	5.0801	9.7027	0.031262	0.845	0.604
EKG	mean R amplitude, mean amplitude of signal measured from isoelectric line to peak of QRS	-0.085160	0.067984	-0.82620	0.598	0.219
EKG	mean SR amplitude, mean amplitude of signal measured from signal minimum line to peak of QRS	-0.15079	0.11924	-0.93311	0.585	0.215
EKG	number of signals	-16.108	7.9747	-2.2304	0.516	0.0518
EKG	proportion of number pairs of successive beat-to-beat intervals that exceed 50 ms	-0.61803	4.9135	-0.067192	0.990	0.901
EKG	QT dispersion, measured as inter-lead variability of QT intervals	-1.6498	1.4705	-0.45667	0.881	0.270
EKG	QTc dispersion, calculated as rate-corrected QT dispersion	-1.6337	1.6551	-0.42557	0.892	0.331
EKG	root mean square of successive differences of neighboring RR intervals	-0.66049	0.50802	-0.21936	0.843	0.203
glucose tolerance test	amount glucose injected	-3.3415	2.3099	-0.59665	0.536	0.170
glucose tolerance test	plasma glucose, 0min	6.5478	5.7502	0.43324	0.490	0.273
glucose tolerance test	plasma glucose, 15min	44.953	28.157	1.3186	0.427	0.133
glucose tolerance test	plasma glucose, 30min	2.9131	23.055	0.22425	0.965	0.901
glucose tolerance test	plasma glucose, 60min	3.8263	15.593	0.29669	0.926	0.809
glucose tolerance test	plasma glucose, 120min	-11.461	10.337	-0.90019	0.595	0.285
grip strength	body weight (at time of grip strength test)	0.80181	0.62815	0.94451	0.407	0.226
grip strength	forelimb and hindlimb grip strength (mean of trials), average	-26.590	6.4142	-1.5723	0.0162	0.00163
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	-1.6245	0.39550	-1.9615	0.0161	0.00145
grip strength	forelimb and hindlimb grip strength by trial, trial1	-20.478	13.248	-1.1084	0.407	0.148
grip strength	forelimb and hindlimb grip strength by trial, trial2	-26.623	17.721	-1.4373	0.396	0.161
grip strength	forelimb and hindlimb grip strength by trial, trial3	-34.882	11.962	-1.8622	0.0961	0.0129
grip strength	forelimb grip strength (mean of trials), average	-21.464	3.9641	-2.0600	0.00727	0.000212
grip strength	forelimb grip strength (mean of trials), average normalized to bw	-1.1059	0.16464	-1.9817	0.00217	0.0000214
grip strength	forelimb grip strength by trial, trial1	-24.908	7.3259	-2.3106	0.0927	0.00593
grip strength	forelimb grip strength by trial, trial2	-20.122	6.4302	-1.7119	0.104	0.00959
grip strength	forelimb grip strength by trial, trial3	-24.180	6.3374	-2.0723	0.0610	0.00287
heart weight	heart weight, normalized to body weight	0.014123	0.16619	-0.40175	0.965	0.933
heart weight	heart weight, weight	-5.4911	4.0314	-1.1268	0.385	0.183
hematology	basophil differential (percent of total WBC)	0.081342	0.075827	1.1352	0.718	0.298
hematology	calculated hemoglobin (cHGB)	0.015379	0.27426	-0.23687	0.984	0.956
hematology	eosinophil differential (percent of total WBC)	0.62103	0.59739	1.6274	0.702	0.313
hematology	hematocrit (HCT)	0.16852	0.82246	-0.20089	0.924	0.840
hematology	hemoglobin concentration distribution width (HDW)	-0.072134	0.022600	-1.7811	0.0747	0.00534
hematology	large unstained cells (percent of total WBC)	0.23682	0.12742	1.4357	0.381	0.0805
hematology	lymphocyte differential (percent of total WBC)	5.6795	2.4630	1.7281	0.174	0.0340
hematology	mean corpuscular hemoglobin (CHr)	-0.015843	0.058433	-0.10875	0.900	0.790
hematology	mean platelet volume (MPV)	-0.26111	0.24246	-1.4358	0.525	0.297
hematology	mean RBC corpuscular hemoglobin (MCH)	0.26913	0.12155	0.98661	0.260	0.0408
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	0.47275	0.25069	0.94150	0.370	0.0765
hematology	mean RBC corpuscular volume (MCV)	-0.15142	0.24181	-0.27827	0.742	0.540
hematology	measured hemoglobin (mHGB)	0.28232	0.25365	0.51329	0.589	0.282
hematology	monocyte differential (percent of total WBC)	-0.055839	0.17443	0.031441	0.910	0.753
hematology	neutrophil differential (percent of total WBC)	-5.8729	2.3441	-1.9140	0.144	0.0227
hematology	platelet count (PLT; units per volume x 10³)	107.52	119.66	1.3683	0.711	0.381
hematology	RBC corpuscular distribution width (RDW)	-0.40094	0.11789	-1.4099	0.0467	0.00340
hematology	RBC corpuscular hemoglobin concentration mean (CHCM)	-0.036968	0.18573	-0.12742	0.936	0.845
hematology	red blood cell count (RBC; per volume x 10⁶)	-0.0087728	0.20409	-0.38267	0.980	0.966
hematology	reticulocyte count (Retic; units per volume x 10⁹)	23.272	24.562	1.0288	0.727	0.357
hematology	reticulocyte differential (percent of total RBC)	0.24792	0.20259	1.1810	0.608	0.238
hematology	white blood cell count (WBC; units per volume x 10³)	1.6526	1.0224	1.2704	0.291	0.126
holeboard	number of hole pokes by individual hole number, 20 min test, 1	-0.86317	1.0702	-0.79213	0.799	0.424
holeboard	number of hole pokes by individual hole number, 20 min test, 2	-0.63161	0.90019	-0.84162	0.870	0.487
holeboard	number of hole pokes by individual hole number, 20 min test, 3	-0.16339	0.61800	-0.19277	0.949	0.793
holeboard	number of hole pokes by individual hole number, 20 min test, 4	-0.41158	0.63201	-0.33444	0.858	0.518
holeboard	number of hole pokes by individual hole number, 20 min test, 5	0.083790	0.57488	0.24464	0.970	0.885
holeboard	number of hole pokes by individual hole number, 20 min test, 6	0.54971	0.44500	1.2877	0.834	0.223
holeboard	number of hole pokes by individual hole number, 20 min test, 7	-0.39965	0.41018	-1.1225	0.852	0.335
holeboard	number of hole pokes by individual hole number, 20 min test, 8	0.22368	0.51438	0.51185	0.935	0.666
holeboard	number of hole pokes by individual hole number, 20 min test, 9	0.34989	0.38050	0.73512	0.816	0.363
holeboard	number of hole pokes by individual hole number, 20 min test, 10	-0.072717	0.29212	-0.12549	0.961	0.805
holeboard	number of hole pokes by individual hole number, 20 min test, 11	-0.14852	0.31724	-0.37334	0.921	0.642
holeboard	number of hole pokes by individual hole number, 20 min test, 12	-0.031053	0.42964	0.050626	0.983	0.943
holeboard	number of hole pokes by individual hole number, 20 min test, 13	-0.86380	0.61037	-0.76747	0.575	0.164
holeboard	number of hole pokes by individual hole number, 20 min test, 14	-1.0231	0.46541	-1.5729	0.368	0.0334
holeboard	number of hole pokes by individual hole number, 20 min test, 15	0.15300	0.60434	0.30315	0.924	0.801
holeboard	number of hole pokes by individual hole number, 20 min test, 16	-1.3217	0.66540	-1.1561	0.408	0.0532
holeboard	total number of hole pokes, 20 min test	-4.5011	4.6459	-0.56312	0.624	0.338
light / dark	latency to enter dark zone, 20 min test	125.88	71.630	1.8398	0.519	0.0863
light / dark	number of transitions between light and dark zones, 20 min test	-4.9716	10.058	-0.39539	0.841	0.624
light / dark	percentage of total time in dark zone, 20 min test	-9.6285	4.9714	-1.5696	0.359	0.0595
light / dark	percentage of total time in light zone, 20 min test	9.6285	4.9714	1.5696	0.357	0.0595
light / dark	time mobile in dark zone, 20 min test	-23.903	15.731	-1.3990	0.421	0.136
light / dark	time mobile in light zone, 20 min test	12.605	10.359	0.51697	0.488	0.231
light / dark	time spent in dark zone, 20 min test	-131.61	64.928	-1.5980	0.366	0.0490
light / dark	time spent in light zone, 20 min test	131.61	64.928	1.5980	0.366	0.0490
open field	average speed in center of arena, 20 min test	-0.074590	0.37529	-0.23785	0.952	0.843
open field	average speed in periphery of arena, 20 min test	0.18006	0.16878	0.20209	0.518	0.292
open field	distance traveled habituation ratio, 20 min test	-0.57705	7.5651	-0.0033565	0.972	0.940
open field	distance traveled in center of arena, 20 min test	144.16	121.88	0.55406	0.498	0.243
open field	distance traveled in periphery of arena, 20 min test	128.49	171.04	0.093446	0.687	0.456
open field	distance traveled slope, 20 min test	-0.89808	6.7777	-0.038273	0.976	0.895
open field	distance traveled, 20 min test, 1st 5min	49.347	74.576	0.061126	0.738	0.511
open field	distance traveled, 20 min test, 2nd 5min	92.124	52.284	0.54002	0.264	0.0847
open field	distance traveled, 20 min test, 3rd 5min	80.726	67.289	0.44897	0.477	0.236
open field	distance traveled, 20 min test, 4th 5min	44.346	63.493	0.039617	0.718	0.488
open field	number of clockwise revolution episodes, 20 min test	1.1109	1.1820	0.23591	0.703	0.352
open field	number of counter-clockwise revolution episodes, 20 min test	1.5475	1.3656	0.40630	0.549	0.263
open field	number of rears in 5 min bins, 20 min test, 1st 5min	-0.040503	2.0414	-0.22487	0.998	0.984
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	-0.13990	2.7532	-0.39612	0.986	0.960
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	-0.66682	2.8202	-0.46088	0.915	0.814
open field	number of rears in 5 min bins, 20 min test, 4th 5min	-2.6987	3.6902	-0.91141	0.713	0.468
open field	percentage of total time in center of arena, 20 min test	1.8627	3.7138	0.22819	0.852	0.618
open field	percentage of total time in center of arena, slope, 20 min test	1.7700	1.6409	1.1007	0.747	0.286
open field	percentage of total time in center, habituation ratio, 20 min test	2.0991	1.6001	1.2596	0.671	0.196
open field	percentage of total time in corners of arena, 20 min test	-6.4818	4.2219	-0.91753	0.436	0.132
open field	percentage of total time in corners, habituation ratio, 20 min test	1.1558	2.1617	0.23923	0.912	0.595
open field	percentage of total time in corners, slope, 20 min test	0.83600	2.0051	0.11099	0.931	0.679
open field	permanence time in center of arena, 20 min test	22.365	44.567	0.22819	0.853	0.618
open field	permanence time in corners of arena, 20 min test	-77.787	50.660	-0.91753	0.436	0.132
open field	permanence time in periphery of arena, 20 min test	-22.374	44.570	-0.22819	0.852	0.618
open field	total distance traveled, 20 min test	266.49	220.77	0.27253	0.445	0.234
open field	total number of rears, 20 min test	-3.4785	10.146	-0.58087	0.868	0.733
open field	whole arena average speed, 20 min test	0.22158	0.18417	0.27113	0.447	0.235
open field	whole arena resting time, 20 min test	-35.106	22.180	-0.40776	0.283	0.120
open field	whole arena time spent mobile, 20 min test	35.115	22.165	0.66065	0.286	0.120
open field	whole arena time spent vertical, 20 min test	-16.827	9.4879	-1.4064	0.333	0.0828
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	-3.0112	1.0643	-1.0913	0.0944	0.00700
startle / PPI	average baseline movement during background noise	1.7933	1.4976	1.0992	0.747	0.236
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	0.083949	0.056924	0.68198	0.485	0.146
startle / PPI	average of each corrected percent pre-pulse inhibition value	0.076861	0.055710	0.68288	0.519	0.173
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-1.9031	6.1892	-0.15261	0.967	0.760
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	8.9410	6.1358	0.86135	0.510	0.151
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	12.098	5.6792	1.1096	0.212	0.0378
startle / PPI	average startle response to full pulse (120 dB)	-48.542	35.588	-0.67317	0.404	0.178
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-42.179	37.160	-0.60107	0.498	0.261
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-56.751	32.322	-0.87977	0.246	0.0849
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-57.261	25.915	-1.0765	0.136	0.0315
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	1.3435	1.4934	0.86135	0.819	0.372
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	0.57081	1.7720	0.40981	0.956	0.749
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	4.3947	2.0027	1.4285	0.314	0.0325
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.029663	0.068729	-0.21819	0.927	0.668
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.096173	0.068537	0.73887	0.511	0.166
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.15250	0.064862	0.97641	0.134	0.0225
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	-50.432	35.719	-0.69977	0.381	0.164
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	-43.417	37.642	-0.61625	0.491	0.254
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	-57.057	32.452	-0.88598	0.242	0.0845
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	-61.417	26.410	-1.1200	0.113	0.0239
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.035207	0.070981	-0.27890	0.930	0.622
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.10832	0.071129	0.75225	0.461	0.134
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.16527	0.064543	0.98094	0.101	0.0133
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	-198.53	132.82	-0.78087	0.346	0.141
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	-161.34	136.72	-0.65050	0.481	0.243
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	-231.07	123.46	-0.98586	0.211	0.0668
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	-235.92	98.672	-1.1658	0.0996	0.0204
startle / PPI	maximum baseline movement during background noise	4.1367	3.7957	1.1305	0.752	0.281
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-2.5522	6.5280	-0.21819	0.951	0.697
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	10.214	6.6027	0.86135	0.464	0.128
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	13.786	5.8663	1.1253	0.155	0.0225
startle / PPI	maximum startle response to full pulse (120 dB)	-194.32	132.85	-0.75267	0.359	0.149
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-158.27	135.65	-0.63499	0.488	0.248
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-228.91	123.02	-0.97679	0.214	0.0683
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-225.62	97.450	-1.1174	0.114	0.0245
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	3.2028	3.6795	0.91968	0.791	0.388
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	2.5584	4.2747	0.70336	0.886	0.552
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	10.534	4.6884	1.3689	0.277	0.0288

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

In this plot, data points are the computed genotype effect % vs. C57BL/6NJ controls, for all measured categorical phenotypes in JaxKOMP-EAP

Dimensions Width: × Height: px

Plot Options Group by Procedure

Include Sexes Data Both Females Males

Significance Threshold p-Value Threshold

Download Plot

Procedure	JaxKOMP-EAP Trait	Sex	Trait Effect	P-value

eye morphology	anterior chamber depth	females	1.0 %	1.0
eye morphology	anterior chamber depth	males	0.0 %	1.0
eye morphology	anterior chamber depth	both	1.0 %	1.0
eye morphology	bulging eye	females	1.0 %	1.00
eye morphology	bulging eye	males	0.0 %	1.0
eye morphology	bulging eye	both	1.0 %	1.00
eye morphology	cornea	females	4.0 %	1.0
eye morphology	cornea	males	2.0 %	1.0
eye morphology	cornea	both	3.0 %	1.00
eye morphology	cornea opacity	females	5.0 %	1.0
eye morphology	cornea opacity	males	1.0 %	1.0
eye morphology	cornea opacity	both	3.0 %	1.0
eye morphology	cornea vascularization	females	3.0 %	1.0
eye morphology	cornea vascularization	males	1.0 %	1.0
eye morphology	cornea vascularization	both	2.0 %	1.0
eye morphology	corneal deposits	females	2.0 %	1.0
eye morphology	corneal deposits	males	1.0 %	1.0
eye morphology	corneal deposits	both	1.0 %	1.00
eye morphology	corneal mineralization	females	2.0 %	1.0
eye morphology	corneal mineralization	males	1.0 %	1.0
eye morphology	corneal mineralization	both	1.0 %	1.0
eye morphology	corneal scleralization	females	3.0 %	1.0
eye morphology	corneal scleralization	males	1.0 %	1.0
eye morphology	corneal scleralization	both	2.0 %	1.0
eye morphology	corneal ulcer	females	1.0 %	1.0
eye morphology	corneal ulcer	males	1.0 %	1.0
eye morphology	corneal ulcer	both	1.0 %	1.0
eye morphology	eye closure	females	1.0 %	1.0
eye morphology	eye closure	males	0.0 %	1.0
eye morphology	eye closure	both	1.0 %	1.00
eye morphology	eye hemorrhage or blood presence	females	2.0 %	1.0
eye morphology	eye hemorrhage or blood presence	males	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	both	1.0 %	1.0
eye morphology	eyelid morphology	females	1.0 %	1.0
eye morphology	eyelid morphology	males	0.0 %	1.0
eye morphology	eyelid morphology	both	1.0 %	1.00
eye morphology	eyes (present, absent)	females	1.0 %	1.0
eye morphology	eyes (present, absent)	males	0.0 %	1.0
eye morphology	eyes (present, absent)	both	0.0 %	1.00
eye morphology	fusion between cornea and lens	females	4.0 %	1.0
eye morphology	fusion between cornea and lens	males	2.0 %	1.0
eye morphology	fusion between cornea and lens	both	3.0 %	1.0
eye morphology	iris pigmentation	females	2.0 %	1.0
eye morphology	iris pigmentation	males	1.0 %	1.0
eye morphology	iris pigmentation	both	2.0 %	1.0
eye morphology	iris transillumination	females	2.0 %	1.0
eye morphology	iris transillumination	males	1.0 %	1.00
eye morphology	iris transillumination	both	1.0 %	1.00
eye morphology	irispupil	females	4.0 %	1.0
eye morphology	irispupil	males	13.0 %	0.198
eye morphology	irispupil	both	8.0 %	0.325
eye morphology	lacrimation	females	3.0 %	1.0
eye morphology	lacrimation	males	2.0 %	1.0
eye morphology	lacrimation	both	3.0 %	1.00
eye morphology	lens	females	10.0 %	1.0
eye morphology	lens	males	8.0 %	1.00
eye morphology	lens	both	9.0 %	1.00
eye morphology	lens opacity	females	9.0 %	1.0
eye morphology	lens opacity	males	6.0 %	1.00
eye morphology	lens opacity	both	7.0 %	1.00
eye morphology	narrow eye opening	females	2.0 %	1.0
eye morphology	narrow eye opening	males	1.0 %	1.0
eye morphology	narrow eye opening	both	1.0 %	1.00
eye morphology	optic disc	females	4.0 %	1.0
eye morphology	optic disc	males	2.0 %	1.00
eye morphology	optic disc	both	3.0 %	1.00
eye morphology	persistence of hyaloid vascular system	females	14.0 %	1.0
eye morphology	persistence of hyaloid vascular system	males	5.0 %	1.0
eye morphology	persistence of hyaloid vascular system	both	9.0 %	1.00
eye morphology	pupil dilation	females	2.0 %	1.0
eye morphology	pupil dilation	males	1.0 %	1.00
eye morphology	pupil dilation	both	2.0 %	1.00
eye morphology	pupil light response	females	2.0 %	1.0
eye morphology	pupil light response	males	1.0 %	1.0
eye morphology	pupil light response	both	2.0 %	1.0
eye morphology	pupil position	females	4.0 %	1.0
eye morphology	pupil position	males	3.0 %	1.0
eye morphology	pupil position	both	4.0 %	1.0
eye morphology	pupil shape	females	3.0 %	1.0
eye morphology	pupil shape	males	2.0 %	1.0
eye morphology	pupil shape	both	3.0 %	1.0
eye morphology	retina	females	10.0 %	1.0
eye morphology	retina	males	27.0 %	0.107
eye morphology	retina	both	14.0 %	0.197
eye morphology	retinal blood vessels	females	4.0 %	1.0
eye morphology	retinal blood vessels	males	2.0 %	1.0
eye morphology	retinal blood vessels	both	3.0 %	1.00
eye morphology	retinal blood vessels pattern	females	5.0 %	1.0
eye morphology	retinal blood vessels pattern	males	2.0 %	1.00
eye morphology	retinal blood vessels pattern	both	4.0 %	1.00
eye morphology	retinal blood vessels structure	females	4.0 %	1.0
eye morphology	retinal blood vessels structure	males	2.0 %	1.0
eye morphology	retinal blood vessels structure	both	3.0 %	1.0
eye morphology	retinal pigmentation	females	12.0 %	1.0
eye morphology	retinal pigmentation	males	14.0 %	1.0
eye morphology	retinal pigmentation	both	13.0 %	1.00
eye morphology	retinal structure	females	4.0 %	1.0
eye morphology	retinal structure	males	2.0 %	1.00
eye morphology	retinal structure	both	3.0 %	1.00
eye morphology	synechia	females	4.0 %	1.0
eye morphology	synechia	males	2.0 %	1.00
eye morphology	synechia	both	3.0 %	1.00
eye morphology	vitreous	females	4.0 %	1.0
eye morphology	vitreous	males	2.0 %	1.0
eye morphology	vitreous	both	3.0 %	1.0
SHIRPA	activity body position	females	1.0 %	1.0
SHIRPA	activity body position	males	2.0 %	1.0
SHIRPA	activity body position	both	1.0 %	1.00
SHIRPA	aggression	females	0.0 %	1.0
SHIRPA	aggression	males	1.0 %	1.0
SHIRPA	aggression	both	1.0 %	1.00
SHIRPA	body length	females	0.0 %	1.0
SHIRPA	body length	males	0.0 %	1.00
SHIRPA	body length	both	0.0 %	1.0
SHIRPA	body position	females	0.0 %	1.0
SHIRPA	body position	males	1.0 %	1.0
SHIRPA	body position	both	0.0 %	1.00
SHIRPA	body thickness	females	1.0 %	1.0
SHIRPA	body thickness	males	0.0 %	1.0
SHIRPA	body thickness	both	0.0 %	1.00
SHIRPA	coat color abdomen	females	39.0 %	0.00143
SHIRPA	coat color abdomen	males	21.0 %	0.0323
SHIRPA	coat color abdomen	both	30.0 %	0.000134
SHIRPA	coat color back	females	0.0 %	1.0
SHIRPA	coat color back	males	0.0 %	1.00
SHIRPA	coat color back	both	0.0 %	1.00
SHIRPA	coat color head	females	0.0 %	1.0
SHIRPA	coat color head	males	0.0 %	1.00
SHIRPA	coat color head	both	0.0 %	1.0
SHIRPA	coat color pattern abdomen	females	1.0 %	1.0
SHIRPA	coat color pattern abdomen	males	1.0 %	1.0
SHIRPA	coat color pattern abdomen	both	1.0 %	1.00
SHIRPA	coat color pattern back	females	0.0 %	1.0
SHIRPA	coat color pattern back	males	0.0 %	1.00
SHIRPA	coat color pattern back	both	0.0 %	1.00
SHIRPA	coat color pattern head	females	0.0 %	1.0
SHIRPA	coat color pattern head	males	0.0 %	1.0
SHIRPA	coat color pattern head	both	0.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	females	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	males	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	both	2.0 %	1.0
SHIRPA	coat hair back texture appearance	females	0.0 %	1.0
SHIRPA	coat hair back texture appearance	males	0.0 %	1.0
SHIRPA	coat hair back texture appearance	both	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	females	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	males	1.0 %	1.00
SHIRPA	coat hair distribution abdomen	both	1.0 %	1.0
SHIRPA	coat hair distribution back	females	0.0 %	1.0
SHIRPA	coat hair distribution back	males	0.0 %	1.0
SHIRPA	coat hair distribution back	both	0.0 %	1.00
SHIRPA	coat hair distribution head	females	28.0 %	0.00140
SHIRPA	coat hair distribution head	males	1.0 %	1.0
SHIRPA	coat hair distribution head	both	13.0 %	0.00474
SHIRPA	coat hair head texture appearance	females	0.0 %	1.0
SHIRPA	coat hair head texture appearance	males	0.0 %	1.0
SHIRPA	coat hair head texture appearance	both	0.0 %	1.0
SHIRPA	contact righting	females	5.0 %	1.0
SHIRPA	contact righting	males	5.0 %	1.00
SHIRPA	contact righting	both	5.0 %	1.00
SHIRPA	ear morphology	females	0.0 %	1.0
SHIRPA	ear morphology	males	0.0 %	1.0
SHIRPA	ear morphology	both	0.0 %	1.0
SHIRPA	fat distribution	females	0.0 %	1.0
SHIRPA	fat distribution	males	0.0 %	1.0
SHIRPA	fat distribution	both	0.0 %	1.0
SHIRPA	forelimb digit number	females	0.0 %	1.0
SHIRPA	forelimb digit number	males	0.0 %	1.0
SHIRPA	forelimb digit number	both	0.0 %	1.0
SHIRPA	forelimb digit position	females	0.0 %	1.0
SHIRPA	forelimb digit position	males	0.0 %	1.0
SHIRPA	forelimb digit position	both	0.0 %	1.0
SHIRPA	forelimb digit shape	females	0.0 %	1.0
SHIRPA	forelimb digit shape	males	0.0 %	1.0
SHIRPA	forelimb digit shape	both	0.0 %	1.0
SHIRPA	forelimb digit size	females	0.0 %	1.0
SHIRPA	forelimb digit size	males	0.0 %	1.0
SHIRPA	forelimb digit size	both	0.0 %	1.0
SHIRPA	forelimb footpads	females	0.0 %	1.0
SHIRPA	forelimb footpads	males	0.0 %	1.0
SHIRPA	forelimb footpads	both	0.0 %	1.0
SHIRPA	forelimb nail length	females	0.0 %	1.0
SHIRPA	forelimb nail length	males	0.0 %	1.0
SHIRPA	forelimb nail length	both	0.0 %	1.0
SHIRPA	forelimb nail number	females	0.0 %	1.0
SHIRPA	forelimb nail number	males	0.0 %	1.0
SHIRPA	forelimb nail number	both	0.0 %	1.0
SHIRPA	forelimb nail position	females	0.0 %	1.0
SHIRPA	forelimb nail position	males	0.0 %	1.0
SHIRPA	forelimb nail position	both	0.0 %	1.0
SHIRPA	forelimb nail shape	females	0.0 %	1.0
SHIRPA	forelimb nail shape	males	0.0 %	1.0
SHIRPA	forelimb nail shape	both	0.0 %	1.0
SHIRPA	forelimbs position	females	0.0 %	1.0
SHIRPA	forelimbs position	males	0.0 %	1.0
SHIRPA	forelimbs position	both	0.0 %	1.0
SHIRPA	forelimbs shape	females	0.0 %	1.0
SHIRPA	forelimbs shape	males	0.0 %	1.0
SHIRPA	forelimbs shape	both	0.0 %	1.0
SHIRPA	forelimbs size	females	0.0 %	1.0
SHIRPA	forelimbs size	males	0.0 %	1.0
SHIRPA	forelimbs size	both	0.0 %	1.0
SHIRPA	forepaw position	females	0.0 %	1.0
SHIRPA	forepaw position	males	0.0 %	1.0
SHIRPA	forepaw position	both	0.0 %	1.0
SHIRPA	forepaw shape	females	0.0 %	1.0
SHIRPA	forepaw shape	males	0.0 %	1.0
SHIRPA	forepaw shape	both	0.0 %	1.0
SHIRPA	forepaw size	females	0.0 %	1.0
SHIRPA	forepaw size	males	0.0 %	1.0
SHIRPA	forepaw size	both	0.0 %	1.0
SHIRPA	gait (fluidity)	females	0.0 %	1.0
SHIRPA	gait (fluidity)	males	0.0 %	1.00
SHIRPA	gait (fluidity)	both	0.0 %	1.0
SHIRPA	genitalia morphology	females	0.0 %	1.0
SHIRPA	genitalia morphology	males	0.0 %	1.0
SHIRPA	genitalia morphology	both	0.0 %	1.00
SHIRPA	genitalia presence	females	0.0 %	1.0
SHIRPA	genitalia presence	males	0.0 %	1.0
SHIRPA	genitalia presence	both	0.0 %	1.0
SHIRPA	genitalia size	females	0.0 %	1.0
SHIRPA	genitalia size	males	0.0 %	1.0
SHIRPA	genitalia size	both	0.0 %	1.00
SHIRPA	head bobbing	females	0.0 %	1.0
SHIRPA	head bobbing	males	0.0 %	1.0
SHIRPA	head bobbing	both	0.0 %	1.0
SHIRPA	head morphology	females	14.0 %	0.00770
SHIRPA	head morphology	males	0.0 %	1.00
SHIRPA	head morphology	both	6.0 %	0.0300
SHIRPA	head size	females	0.0 %	1.0
SHIRPA	head size	males	0.0 %	1.0
SHIRPA	head size	both	0.0 %	1.0
SHIRPA	hindlimb digit number	females	1.0 %	1.0
SHIRPA	hindlimb digit number	males	0.0 %	1.0
SHIRPA	hindlimb digit number	both	0.0 %	1.0
SHIRPA	hindlimb digit position	females	0.0 %	1.0
SHIRPA	hindlimb digit position	males	0.0 %	1.0
SHIRPA	hindlimb digit position	both	0.0 %	1.0
SHIRPA	hindlimb digit shape	females	0.0 %	1.0
SHIRPA	hindlimb digit shape	males	0.0 %	1.0
SHIRPA	hindlimb digit shape	both	0.0 %	1.00
SHIRPA	hindlimb digit size	females	0.0 %	1.0
SHIRPA	hindlimb digit size	males	0.0 %	1.0
SHIRPA	hindlimb digit size	both	0.0 %	1.00
SHIRPA	hindlimb nail length	females	0.0 %	1.0
SHIRPA	hindlimb nail length	males	0.0 %	1.0
SHIRPA	hindlimb nail length	both	0.0 %	1.0
SHIRPA	hindlimb nail number	females	0.0 %	1.0
SHIRPA	hindlimb nail number	males	1.0 %	1.0
SHIRPA	hindlimb nail number	both	0.0 %	1.0
SHIRPA	hindlimb nail position	females	0.0 %	1.0
SHIRPA	hindlimb nail position	males	0.0 %	1.0
SHIRPA	hindlimb nail position	both	0.0 %	1.0
SHIRPA	hindlimb nail shape	females	0.0 %	1.0
SHIRPA	hindlimb nail shape	males	0.0 %	1.0
SHIRPA	hindlimb nail shape	both	0.0 %	1.0
SHIRPA	hindlimbs footpads	females	0.0 %	1.0
SHIRPA	hindlimbs footpads	males	0.0 %	1.0
SHIRPA	hindlimbs footpads	both	0.0 %	1.0
SHIRPA	hindlimbs position	females	0.0 %	1.0
SHIRPA	hindlimbs position	males	0.0 %	1.0
SHIRPA	hindlimbs position	both	0.0 %	1.0
SHIRPA	hindlimbs shape	females	0.0 %	1.0
SHIRPA	hindlimbs shape	males	0.0 %	1.0
SHIRPA	hindlimbs shape	both	0.0 %	1.0
SHIRPA	hindlimbs size	females	0.0 %	1.0
SHIRPA	hindlimbs size	males	0.0 %	1.0
SHIRPA	hindlimbs size	both	0.0 %	1.0
SHIRPA	hindpaw position	females	0.0 %	1.0
SHIRPA	hindpaw position	males	0.0 %	1.0
SHIRPA	hindpaw position	both	0.0 %	1.0
SHIRPA	hindpaw shape	females	0.0 %	1.0
SHIRPA	hindpaw shape	males	0.0 %	1.0
SHIRPA	hindpaw shape	both	0.0 %	1.0
SHIRPA	hindpaw size	females	0.0 %	1.0
SHIRPA	hindpaw size	males	0.0 %	1.0
SHIRPA	hindpaw size	both	0.0 %	1.0
SHIRPA	limb grasp	females	34.0 %	0.0188
SHIRPA	limb grasp	males	7.0 %	0.375
SHIRPA	limb grasp	both	19.0 %	0.0202
SHIRPA	lower lip morphology	females	0.0 %	1.0
SHIRPA	lower lip morphology	males	0.0 %	1.0
SHIRPA	lower lip morphology	both	0.0 %	1.0
SHIRPA	lower teeth appearance	females	0.0 %	1.0
SHIRPA	lower teeth appearance	males	0.0 %	1.00
SHIRPA	lower teeth appearance	both	0.0 %	1.0
SHIRPA	mouth morphology	females	0.0 %	1.0
SHIRPA	mouth morphology	males	0.0 %	1.00
SHIRPA	mouth morphology	both	0.0 %	1.0
SHIRPA	salivation	females	0.0 %	1.0
SHIRPA	salivation	males	0.0 %	1.0
SHIRPA	salivation	both	0.0 %	1.0
SHIRPA	skin color back paws	females	0.0 %	1.0
SHIRPA	skin color back paws	males	0.0 %	1.0
SHIRPA	skin color back paws	both	0.0 %	1.0
SHIRPA	skin color ear	females	0.0 %	1.0
SHIRPA	skin color ear	males	0.0 %	1.0
SHIRPA	skin color ear	both	0.0 %	1.0
SHIRPA	skin color front paws	females	0.0 %	1.0
SHIRPA	skin color front paws	males	0.0 %	1.0
SHIRPA	skin color front paws	both	0.0 %	1.0
SHIRPA	skin color snout	females	0.0 %	1.0
SHIRPA	skin color snout	males	0.0 %	1.0
SHIRPA	skin color snout	both	0.0 %	1.0
SHIRPA	skin color tail	females	0.0 %	1.0
SHIRPA	skin color tail	males	0.0 %	1.0
SHIRPA	skin color tail	both	0.0 %	1.0
SHIRPA	skin color whole body	females	0.0 %	1.0
SHIRPA	skin color whole body	males	0.0 %	1.0
SHIRPA	skin color whole body	both	0.0 %	1.0
SHIRPA	skin texture back paw	females	0.0 %	1.0
SHIRPA	skin texture back paw	males	0.0 %	1.0
SHIRPA	skin texture back paw	both	0.0 %	1.0
SHIRPA	skin texture ear	females	0.0 %	1.0
SHIRPA	skin texture ear	males	0.0 %	1.0
SHIRPA	skin texture ear	both	0.0 %	1.0
SHIRPA	skin texture front paws	females	0.0 %	1.0
SHIRPA	skin texture front paws	males	0.0 %	1.0
SHIRPA	skin texture front paws	both	0.0 %	1.0
SHIRPA	skin texture snout	females	0.0 %	1.0
SHIRPA	skin texture snout	males	0.0 %	1.0
SHIRPA	skin texture snout	both	0.0 %	1.0
SHIRPA	skin texture tail	females	0.0 %	1.0
SHIRPA	skin texture tail	males	0.0 %	1.0
SHIRPA	skin texture tail	both	0.0 %	1.0
SHIRPA	skin texture whole body	females	0.0 %	1.0
SHIRPA	skin texture whole body	males	0.0 %	1.00
SHIRPA	skin texture whole body	both	0.0 %	1.00
SHIRPA	snout size	females	0.0 %	1.0
SHIRPA	snout size	males	1.0 %	1.0
SHIRPA	snout size	both	0.0 %	1.0
SHIRPA	startle response	females	0.0 %	1.0
SHIRPA	startle response	males	0.0 %	1.00
SHIRPA	startle response	both	0.0 %	1.0
SHIRPA	tail curvature	females	0.0 %	1.00
SHIRPA	tail curvature	males	0.0 %	1.0
SHIRPA	tail curvature	both	0.0 %	1.00
SHIRPA	tail elevation	females	1.0 %	1.0
SHIRPA	tail elevation	males	2.0 %	1.0
SHIRPA	tail elevation	both	1.0 %	1.0
SHIRPA	tail length	females	0.0 %	1.0
SHIRPA	tail length	males	0.0 %	1.0
SHIRPA	tail length	both	0.0 %	1.0
SHIRPA	tail morphology	females	0.0 %	1.0
SHIRPA	tail morphology	males	0.0 %	1.0
SHIRPA	tail morphology	both	0.0 %	1.00
SHIRPA	tail presence	females	0.0 %	1.0
SHIRPA	tail presence	males	0.0 %	1.0
SHIRPA	tail presence	both	0.0 %	1.0
SHIRPA	tail shape	females	0.0 %	1.0
SHIRPA	tail shape	males	0.0 %	1.0
SHIRPA	tail shape	both	0.0 %	1.0
SHIRPA	tail thickness	females	0.0 %	1.0
SHIRPA	tail thickness	males	0.0 %	1.0
SHIRPA	tail thickness	both	0.0 %	1.0
SHIRPA	teeth presence	females	0.0 %	1.0
SHIRPA	teeth presence	males	0.0 %	1.00
SHIRPA	teeth presence	both	0.0 %	1.0
SHIRPA	transfer arousal	females	1.0 %	1.0
SHIRPA	transfer arousal	males	12.0 %	0.00656
SHIRPA	transfer arousal	both	7.0 %	0.00379
SHIRPA	tremor	females	0.0 %	1.0
SHIRPA	tremor	males	0.0 %	1.0
SHIRPA	tremor	both	0.0 %	1.00
SHIRPA	trunk curl	females	0.0 %	1.0
SHIRPA	trunk curl	males	0.0 %	1.0
SHIRPA	trunk curl	both	0.0 %	1.00
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	females	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	males	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	both	0.0 %	1.0
SHIRPA	upper lip morphology	females	0.0 %	1.0
SHIRPA	upper lip morphology	males	0.0 %	1.0
SHIRPA	upper lip morphology	both	0.0 %	1.0
SHIRPA	upper teeth appearance	females	0.0 %	1.0
SHIRPA	upper teeth appearance	males	0.0 %	1.0
SHIRPA	upper teeth appearance	both	0.0 %	1.0
SHIRPA	vibrissae appearance	females	2.0 %	1.0
SHIRPA	vibrissae appearance	males	1.0 %	1.0
SHIRPA	vibrissae appearance	both	1.0 %	1.0
SHIRPA	vibrissae presence	females	12.0 %	0.156
SHIRPA	vibrissae presence	males	1.0 %	1.0
SHIRPA	vibrissae presence	both	5.0 %	0.211
SHIRPA	vocalization	females	2.0 %	1.00
SHIRPA	vocalization	males	2.0 %	1.0
SHIRPA	vocalization	both	2.0 %	1.0

GENOTYPE CORRELATION PLOT

Correlate Tesk1^em1(IMPC)J/Mmjax -/- with genotype: