MPD: JaxKOMP-EAP genotype: Rab28<sup>em1(IMPC)J</sup>/Mmjax -/-

JaxKOMP-EAP effect sizes: Rab28^em1(IMPC)J/Mmjax -/- Gene Rab28

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

In this plot, data points are the computed genotype effect size vs. C57BL/6NJ controls, for all measured numeric phenotypes in JaxKOMP-EAP

Dimensions Width: × Height: px

Plot Options Group by Procedure Standard Error Show Effect Sizes RankZ

Significance Threshold p-Value Threshold Adjusted Unadjusted

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Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value

ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	1.4481	2.7571	0.17228	0.875	0.607
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	-8.3333	2.1768	-1.4878	0.0710	0.00165
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	-1.0417	2.5957	-0.41881	0.896	0.694
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	7.5669	4.6480	1.0837	0.476	0.124
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	0.20058	4.4469	-0.0056077	0.988	0.965
body composition	body length	-0.55511	0.054360	-2.5105	3.23e-9	3.54e-12
body composition	body weight (at time of DXA)	0.95876	0.76949	0.87996	0.436	0.221
body composition	bone area, whole body scan, head excluded	-1.4039	0.18862	-3.0647	0.00000449	7.34e-9
body composition	bone mineral content of whole body scan, head excluded	-0.091295	0.014977	-3.0647	0.000158	5.18e-7
body composition	bone mineral content to body weight ratio	-0.0038201	0.00064741	-2.9413	0.000157	9.43e-7
body composition	bone mineral density of whole body scan, head excluded	-0.0026817	0.00081278	-2.1493	0.0385	0.00219
body composition	fat tissue mass of whole body scan, head excluded	2.5332	0.45197	2.6231	0.000478	0.00000235
body composition	fat tissue mass to body weight ratio	0.098619	0.015415	2.7794	0.0000968	2.05e-7
body composition	lean tissue mass of whole body scan, head excluded	-2.2367	0.37465	-3.0647	0.000280	7.62e-7
body composition	lean tissue mass to body weight ratio	-0.077542	0.014806	-2.7792	0.00133	0.00000727
body composition	percent fat, whole body scan, head excluded	9.5537	1.4747	3.0647	0.0000834	1.60e-7
body composition	ratio of soft-tissue attenuation coefficients	-0.011328	0.0014197	-3.0641	0.00000109	1.78e-9
body composition	tissue area	0.33265	0.20088	1.1779	0.361	0.106
body composition	total tissue mass, whole body scan, head excluded	0.71318	0.25804	1.1813	0.0644	0.00895
clinical blood chemistry	alanine transaminase (plasma ALT)	-9.1587	18.074	-0.78212	0.875	0.619
clinical blood chemistry	albumin (plasma Alb)	-1.0383	0.45847	-1.2777	0.229	0.0354
clinical blood chemistry	alkaline phosphatase (plasma ALP)	-7.9003	4.1498	-1.7759	0.249	0.0751
clinical blood chemistry	aspartate transaminase (plasma AST)	-10.701	15.007	-0.52668	0.773	0.485
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	-0.32011	0.18461	-0.98188	0.479	0.101
clinical blood chemistry	blood urea nitrogen (BUN)	0.19634	1.6087	0.037988	0.949	0.904
clinical blood chemistry	calcium (plasma Ca)	-0.14099	0.10000	-0.67762	0.403	0.177
clinical blood chemistry	creatinine (plasma)	0.0067901	0.022903	0.25926	0.875	0.770
clinical blood chemistry	glucose (plasma GLU, no fast)	20.789	17.724	1.1108	0.462	0.257
clinical blood chemistry	HDL cholesterol (plasma HDL)	2.3820	3.5823	0.23816	0.772	0.516
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	0.00047773	0.011453	-0.13348	0.995	0.967
clinical blood chemistry	phosphorus (plasma phosphate)	0.89342	0.56101	1.2684	0.374	0.130
clinical blood chemistry	total bilirubin (plasma TBIL)	0.010321	0.0093173	0.65062	0.633	0.283
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	3.2960	4.5621	0.35192	0.767	0.480
clinical blood chemistry	total protein (plasma TP)	-2.5963	0.69780	-1.7935	0.0368	0.00170
clinical blood chemistry	triglyceride (plasma TG, no fast)	41.169	14.702	1.8688	0.110	0.0128
EKG	duration of PQ interval	0.49871	1.0532	0.67449	0.931	0.639
EKG	duration of PR interval	0.55398	1.0452	0.64940	0.932	0.599
EKG	duration of QRS interval	-0.11515	0.15128	-0.45667	0.911	0.451
EKG	duration of QT interval	-1.3926	0.64183	-1.1103	0.482	0.0367
EKG	duration of QTC interval, calculated by dividing QT interval by square root of preceding RR interval	-1.2983	0.66758	-1.2926	0.641	0.0596
EKG	duration of RR interval	-1.6046	1.1996	-0.59079	0.605	0.189
EKG	duration of ST interval	-1.2862	0.65061	-1.0248	0.513	0.0558
EKG	heart rate coefficient of variation (signal intensity)	0.10651	0.92728	0.17826	0.982	0.909
EKG	heart rate variability, mean of differences between sequential beats; beats per min	1.8371	6.6862	0.29225	0.965	0.785
EKG	heart rate, beats per min	14.309	10.463	0.60459	0.573	0.180
EKG	mean R amplitude, mean amplitude of signal measured from isoelectric line to peak of QRS	-0.063939	0.052855	-0.64876	0.607	0.234
EKG	mean SR amplitude, mean amplitude of signal measured from signal minimum line to peak of QRS	-0.086097	0.093150	-0.59734	0.696	0.361
EKG	number of signals	5.5558	9.2655	1.0180	0.883	0.553
EKG	proportion of number pairs of successive beat-to-beat intervals that exceed 50 ms	1.3756	5.2754	0.34012	0.973	0.796
EKG	QT dispersion, measured as inter-lead variability of QT intervals	0.94314	1.5727	0.30700	0.964	0.552
EKG	QTc dispersion, calculated as rate-corrected QT dispersion	2.2655	1.8295	0.57170	0.863	0.224
EKG	root mean square of successive differences of neighboring RR intervals	0.98954	0.75610	0.65689	0.843	0.199
glucose tolerance test	amount glucose injected	-6913.2	9333.6	-2.9391	0.784	0.463
glucose tolerance test	plasma glucose, 0min	10.957	4.4908	0.88385	0.0854	0.0184
glucose tolerance test	plasma glucose, 15min	58.553	15.512	1.6103	0.0216	0.000441
glucose tolerance test	plasma glucose, 30min	30.999	13.606	1.0339	0.183	0.0273
glucose tolerance test	plasma glucose, 60min	37.558	11.750	1.5128	0.0582	0.00249
glucose tolerance test	plasma glucose, 120min	49.016	8.4105	2.3531	0.000179	4.90e-7
grip strength	body weight (at time of grip strength test)	-2.6359	0.66862	-1.7515	0.00557	0.000490
grip strength	forelimb and hindlimb grip strength (mean of trials), average	-30.008	8.9480	-1.7785	0.0211	0.00237
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	-1.6153	0.49134	-1.9419	0.0250	0.00281
grip strength	forelimb and hindlimb grip strength by trial, trial1	-35.799	14.712	-1.9232	0.139	0.0219
grip strength	forelimb and hindlimb grip strength by trial, trial2	-22.542	12.961	-1.1782	0.288	0.0934
grip strength	forelimb and hindlimb grip strength by trial, trial3	-23.279	9.7039	-1.2323	0.137	0.0236
grip strength	forelimb grip strength (mean of trials), average	-7.4158	5.3856	-0.68088	0.424	0.180
grip strength	forelimb grip strength (mean of trials), average normalized to bw	-0.40090	0.29792	-0.78739	0.449	0.190
grip strength	forelimb grip strength by trial, trial1	-13.112	4.8891	-1.1841	0.137	0.0121
grip strength	forelimb grip strength by trial, trial2	5.6267	6.1096	0.86082	0.687	0.365
grip strength	forelimb grip strength by trial, trial3	-18.404	6.1655	-1.5478	0.0870	0.00583
heart weight	heart weight, normalized to body weight	-0.52241	0.10668	-2.1270	0.00216	0.0000676
heart weight	heart weight, weight	-14.966	3.4457	-2.2794	0.00582	0.000261
hematology	basophil differential (percent of total WBC)	0.19454	0.071542	1.9854	0.227	0.0141
hematology	calculated hemoglobin (cHGB)	0.29524	0.21561	0.63890	0.466	0.188
hematology	eosinophil differential (percent of total WBC)	-0.0083333	0.21977	0.059521	0.989	0.970
hematology	hematocrit (HCT)	1.0476	0.58384	0.85297	0.346	0.0896
hematology	hemoglobin concentration distribution width (HDW)	-0.018416	0.030321	-0.50772	0.775	0.551
hematology	large unstained cells (percent of total WBC)	0.32890	0.10786	1.8075	0.126	0.00690
hematology	lymphocyte differential (percent of total WBC)	1.7488	1.8066	0.63637	0.597	0.346
hematology	mean corpuscular hemoglobin (CHr)	0.11069	0.074553	0.86470	0.368	0.155
hematology	mean platelet volume (MPV)	0.0034910	0.067672	-0.17304	0.980	0.959
hematology	mean RBC corpuscular hemoglobin (MCH)	0.11667	0.17768	0.42246	0.797	0.520
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	-0.075000	0.36017	-0.16789	0.946	0.837
hematology	mean RBC corpuscular volume (MCV)	0.47141	0.33253	0.81618	0.371	0.173
hematology	measured hemoglobin (mHGB)	0.30595	0.17415	0.57676	0.353	0.0960
hematology	monocyte differential (percent of total WBC)	0.19724	0.12913	0.84709	0.506	0.145
hematology	neutrophil differential (percent of total WBC)	-2.0869	1.6453	-0.87280	0.471	0.221
hematology	platelet count (PLT; units per volume x 10³)	-78.496	40.464	-0.96234	0.376	0.0682
hematology	RBC corpuscular distribution width (RDW)	-0.13968	0.20094	-0.50983	0.721	0.496
hematology	RBC corpuscular hemoglobin concentration mean (CHCM)	-0.077381	0.21888	-0.25335	0.872	0.728
hematology	red blood cell count (RBC; per volume x 10⁶)	0.12833	0.15947	0.24883	0.680	0.431
hematology	reticulocyte count (Retic; units per volume x 10⁹)	13.795	19.326	0.66804	0.803	0.484
hematology	reticulocyte differential (percent of total RBC)	0.089881	0.20342	0.60246	0.868	0.664
hematology	white blood cell count (WBC; units per volume x 10³)	0.69797	0.87110	0.64644	0.626	0.433
holeboard	number of hole pokes by individual hole number, 20 min test, 1	0.86406	0.70557	0.87085	0.705	0.226
holeboard	number of hole pokes by individual hole number, 20 min test, 2	0.16144	0.46235	0.40494	0.945	0.728
holeboard	number of hole pokes by individual hole number, 20 min test, 3	0.27935	0.43445	0.55466	0.891	0.523
holeboard	number of hole pokes by individual hole number, 20 min test, 4	0.25817	0.98354	0.33087	0.937	0.794
holeboard	number of hole pokes by individual hole number, 20 min test, 5	0.76005	0.41734	1.2350	0.570	0.0737
holeboard	number of hole pokes by individual hole number, 20 min test, 6	0.38028	0.33055	0.99379	0.834	0.255
holeboard	number of hole pokes by individual hole number, 20 min test, 7	0.48053	0.25029	1.2128	0.689	0.0598
holeboard	number of hole pokes by individual hole number, 20 min test, 8	0.63882	0.55455	1.1491	0.759	0.254
holeboard	number of hole pokes by individual hole number, 20 min test, 9	0.72090	0.43112	1.2641	0.531	0.0999
holeboard	number of hole pokes by individual hole number, 20 min test, 10	0.49116	0.24752	1.1880	0.653	0.0520
holeboard	number of hole pokes by individual hole number, 20 min test, 11	0.37073	0.32674	0.88527	0.807	0.261
holeboard	number of hole pokes by individual hole number, 20 min test, 12	0.99560	0.58993	1.5280	0.532	0.0968
holeboard	number of hole pokes by individual hole number, 20 min test, 13	0.87918	0.65020	0.93733	0.597	0.182
holeboard	number of hole pokes by individual hole number, 20 min test, 14	1.7919	0.49923	2.3486	0.169	0.000683
holeboard	number of hole pokes by individual hole number, 20 min test, 15	0.66269	0.43176	1.1112	0.614	0.130
holeboard	number of hole pokes by individual hole number, 20 min test, 16	1.2917	0.81181	1.1398	0.548	0.117
holeboard	total number of hole pokes, 20 min test	10.144	4.8061	1.3356	0.224	0.0391
light / dark	latency to enter dark zone, 20 min test	-42.035	63.838	-0.89242	0.840	0.513
light / dark	number of transitions between light and dark zones, 20 min test	-21.154	7.9075	-1.8938	0.116	0.00996
light / dark	percentage of total time in dark zone, 20 min test	11.156	4.1764	2.0436	0.178	0.0101
light / dark	percentage of total time in light zone, 20 min test	-11.156	4.1764	-2.0436	0.178	0.0101
light / dark	time mobile in dark zone, 20 min test	1.3476	15.015	0.010816	0.974	0.929
light / dark	time mobile in light zone, 20 min test	-19.968	9.9239	-1.5837	0.211	0.0494
light / dark	time spent in dark zone, 20 min test	107.60	56.162	1.7517	0.408	0.0610
light / dark	time spent in light zone, 20 min test	-107.60	56.162	-1.7517	0.408	0.0610
open field	average speed in center of arena, 20 min test	-0.58140	0.28382	-1.2134	0.290	0.0450
open field	average speed in periphery of arena, 20 min test	0.13171	0.17481	0.020812	0.682	0.454
open field	distance traveled habituation ratio, 20 min test	1.9987	6.6062	0.20757	0.901	0.763
open field	distance traveled in center of arena, 20 min test	-9.6556	89.978	-0.43860	0.956	0.915
open field	distance traveled in periphery of arena, 20 min test	94.074	172.15	-0.049024	0.772	0.587
open field	distance traveled slope, 20 min test	1.4786	6.4243	0.21993	0.941	0.819
open field	distance traveled, 20 min test, 1st 5min	-32.328	57.854	-0.62597	0.790	0.578
open field	distance traveled, 20 min test, 2nd 5min	5.4915	52.586	-0.43564	0.959	0.917
open field	distance traveled, 20 min test, 3rd 5min	-1.3247	50.262	-0.45939	0.997	0.979
open field	distance traveled, 20 min test, 4th 5min	29.479	64.097	-0.10694	0.814	0.647
open field	number of clockwise revolution episodes, 20 min test	-0.076781	0.93044	-0.45146	0.979	0.935
open field	number of counter-clockwise revolution episodes, 20 min test	-1.1294	1.4058	-1.0458	0.693	0.425
open field	number of rears in 5 min bins, 20 min test, 1st 5min	-1.3362	1.4987	-0.57091	0.632	0.376
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	-0.022193	2.2644	-0.36150	0.996	0.992
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	-3.2176	1.9096	-1.0528	0.321	0.0974
open field	number of rears in 5 min bins, 20 min test, 4th 5min	-3.2075	2.3355	-1.0297	0.443	0.175
open field	percentage of total time in center of arena, 20 min test	2.9097	3.0306	0.43712	0.657	0.341
open field	percentage of total time in center of arena, slope, 20 min test	-3.8292	1.4230	-1.7612	0.262	0.00929
open field	percentage of total time in center, habituation ratio, 20 min test	-4.1211	1.4687	-1.7740	0.227	0.00682
open field	percentage of total time in corners of arena, 20 min test	-0.39769	3.9917	0.24061	0.968	0.921
open field	percentage of total time in corners, habituation ratio, 20 min test	-0.59172	2.0606	-0.56347	0.959	0.775
open field	percentage of total time in corners, slope, 20 min test	-0.56712	1.9952	-0.54002	0.950	0.777
open field	permanence time in center of arena, 20 min test	34.912	36.368	0.43860	0.657	0.341
open field	permanence time in corners of arena, 20 min test	-4.7643	47.901	0.24061	0.968	0.921
open field	permanence time in periphery of arena, 20 min test	-34.896	36.363	-0.43712	0.658	0.341
open field	total distance traveled, 20 min test	63.427	216.90	-0.30613	0.884	0.771
open field	total number of rears, 20 min test	-7.4360	6.8028	-0.86169	0.534	0.279
open field	whole arena average speed, 20 min test	0.052729	0.18094	-0.30191	0.885	0.772
open field	whole arena resting time, 20 min test	-10.314	19.144	0.24891	0.754	0.592
open field	whole arena time spent mobile, 20 min test	10.174	19.152	-0.058436	0.761	0.597
open field	whole arena time spent vertical, 20 min test	-13.488	6.4726	-1.1487	0.242	0.0416
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	1.9512	1.6901	1.0218	0.577	0.258
startle / PPI	average baseline movement during background noise	0.67206	1.2000	0.51270	0.913	0.578
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	0.10139	0.079863	0.82536	0.577	0.210
startle / PPI	average of each corrected percent pre-pulse inhibition value	0.11119	0.075469	0.98057	0.486	0.147
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	8.9156	8.4437	1.0183	0.877	0.296
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	11.060	8.1080	1.0715	0.542	0.179
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	9.2897	6.2739	0.83923	0.420	0.145
startle / PPI	average startle response to full pulse (120 dB)	-67.746	29.755	-0.99501	0.128	0.0272
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-37.487	34.888	-0.52231	0.528	0.288
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-29.396	33.859	-0.42817	0.599	0.390
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-55.907	27.346	-1.0421	0.173	0.0463
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	-2.6250	1.0345	-1.6984	0.418	0.0144
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	-0.017769	1.4503	0.016114	0.998	0.990
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	-1.9304	1.8140	-1.1658	0.708	0.292
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.092982	0.093009	0.91328	0.869	0.322
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.13416	0.092532	1.0246	0.493	0.153
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.12101	0.082272	0.76158	0.381	0.148
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	-66.725	29.667	-0.96110	0.131	0.0290
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	-34.952	34.708	-0.49520	0.556	0.319
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	-29.080	33.961	-0.41286	0.603	0.396
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	-54.289	27.513	-0.98358	0.188	0.0541
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.11266	0.10166	0.99042	0.853	0.273
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.10547	0.097783	0.73561	0.631	0.286
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.10447	0.083508	0.59391	0.477	0.217
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	-250.24	116.89	-0.99962	0.151	0.0373
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	-147.93	135.75	-0.58603	0.520	0.281
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	-96.420	130.47	-0.35404	0.657	0.463
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	-188.85	107.47	-0.92827	0.245	0.0851
startle / PPI	maximum baseline movement during background noise	-1.0507	2.5439	-0.23689	0.936	0.681
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	10.620	9.5762	1.0992	0.884	0.273
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	8.7019	8.9385	0.72142	0.684	0.335
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	7.8765	6.9252	0.60443	0.554	0.261
startle / PPI	maximum startle response to full pulse (120 dB)	-253.80	117.16	-1.0136	0.149	0.0352
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-155.12	136.00	-0.62304	0.500	0.260
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-98.210	130.08	-0.36600	0.656	0.454
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-192.64	107.18	-0.96333	0.238	0.0784
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	-6.7542	2.0842	-1.7543	0.290	0.00215
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	-1.2343	3.3875	-0.32140	0.943	0.717
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	-4.4644	4.1422	-1.1253	0.671	0.286

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

In this plot, data points are the computed genotype effect % vs. C57BL/6NJ controls, for all measured categorical phenotypes in JaxKOMP-EAP

Dimensions Width: × Height: px

Plot Options Group by Procedure

Include Sexes Data Both Females Males

Significance Threshold p-Value Threshold

Download Plot

Procedure	JaxKOMP-EAP Trait	Sex	Trait Effect	P-value

eye morphology	anterior chamber depth	females	1.0 %	1.0
eye morphology	anterior chamber depth	males	0.0 %	1.0
eye morphology	anterior chamber depth	both	1.0 %	1.0
eye morphology	bulging eye	females	1.0 %	1.0
eye morphology	bulging eye	males	0.0 %	1.0
eye morphology	bulging eye	both	1.0 %	1.00
eye morphology	cornea	females	4.0 %	1.0
eye morphology	cornea	males	2.0 %	1.0
eye morphology	cornea	both	3.0 %	1.00
eye morphology	cornea opacity	females	5.0 %	1.00
eye morphology	cornea opacity	males	1.0 %	1.0
eye morphology	cornea opacity	both	3.0 %	1.00
eye morphology	cornea vascularization	females	3.0 %	1.0
eye morphology	cornea vascularization	males	1.0 %	1.0
eye morphology	cornea vascularization	both	2.0 %	1.00
eye morphology	corneal deposits	females	2.0 %	1.0
eye morphology	corneal deposits	males	1.0 %	1.0
eye morphology	corneal deposits	both	1.0 %	1.00
eye morphology	corneal mineralization	females	2.0 %	1.0
eye morphology	corneal mineralization	males	1.0 %	1.0
eye morphology	corneal mineralization	both	1.0 %	1.00
eye morphology	corneal scleralization	females	3.0 %	1.00
eye morphology	corneal scleralization	males	1.0 %	1.0
eye morphology	corneal scleralization	both	2.0 %	1.00
eye morphology	corneal ulcer	females	1.0 %	1.0
eye morphology	corneal ulcer	males	1.0 %	1.0
eye morphology	corneal ulcer	both	1.0 %	1.00
eye morphology	eye closure	females	1.0 %	1.00
eye morphology	eye closure	males	0.0 %	1.0
eye morphology	eye closure	both	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	females	2.0 %	1.00
eye morphology	eye hemorrhage or blood presence	males	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	both	1.0 %	1.00
eye morphology	eyelid morphology	females	1.0 %	1.0
eye morphology	eyelid morphology	males	0.0 %	1.0
eye morphology	eyelid morphology	both	1.0 %	1.0
eye morphology	eyes (present, absent)	females	1.0 %	1.0
eye morphology	eyes (present, absent)	males	0.0 %	1.0
eye morphology	eyes (present, absent)	both	0.0 %	1.0
eye morphology	fusion between cornea and lens	females	4.0 %	1.00
eye morphology	fusion between cornea and lens	males	2.0 %	1.0
eye morphology	fusion between cornea and lens	both	3.0 %	1.00
eye morphology	iris pigmentation	females	2.0 %	1.0
eye morphology	iris pigmentation	males	1.0 %	1.0
eye morphology	iris pigmentation	both	2.0 %	1.00
eye morphology	iris transillumination	females	2.0 %	1.00
eye morphology	iris transillumination	males	1.0 %	1.0
eye morphology	iris transillumination	both	1.0 %	1.00
eye morphology	irispupil	females	4.0 %	1.00
eye morphology	irispupil	males	3.0 %	1.0
eye morphology	irispupil	both	3.0 %	1.00
eye morphology	lacrimation	females	3.0 %	1.0
eye morphology	lacrimation	males	2.0 %	1.0
eye morphology	lacrimation	both	3.0 %	1.0
eye morphology	lens	females	10.0 %	1.00
eye morphology	lens	males	8.0 %	1.0
eye morphology	lens	both	9.0 %	1.0
eye morphology	lens opacity	females	9.0 %	1.0
eye morphology	lens opacity	males	6.0 %	1.0
eye morphology	lens opacity	both	7.0 %	1.00
eye morphology	narrow eye opening	females	2.0 %	1.0
eye morphology	narrow eye opening	males	1.0 %	1.0
eye morphology	narrow eye opening	both	1.0 %	1.0
eye morphology	optic disc	females	4.0 %	1.00
eye morphology	optic disc	males	2.0 %	1.0
eye morphology	optic disc	both	3.0 %	1.00
eye morphology	persistence of hyaloid vascular system	females	14.0 %	1.0
eye morphology	persistence of hyaloid vascular system	males	5.0 %	1.0
eye morphology	persistence of hyaloid vascular system	both	9.0 %	1.00
eye morphology	pupil dilation	females	2.0 %	1.0
eye morphology	pupil dilation	males	1.0 %	1.0
eye morphology	pupil dilation	both	2.0 %	1.0
eye morphology	pupil light response	females	2.0 %	1.00
eye morphology	pupil light response	males	1.0 %	1.0
eye morphology	pupil light response	both	2.0 %	1.00
eye morphology	pupil position	females	4.0 %	1.00
eye morphology	pupil position	males	3.0 %	1.0
eye morphology	pupil position	both	4.0 %	1.00
eye morphology	pupil shape	females	3.0 %	1.00
eye morphology	pupil shape	males	2.0 %	1.0
eye morphology	pupil shape	both	3.0 %	1.00
eye morphology	retina	females	10.0 %	1.0
eye morphology	retina	males	16.0 %	1.0
eye morphology	retina	both	13.0 %	1.0
eye morphology	retinal blood vessels	females	4.0 %	1.0
eye morphology	retinal blood vessels	males	2.0 %	1.0
eye morphology	retinal blood vessels	both	3.0 %	1.0
eye morphology	retinal blood vessels pattern	females	5.0 %	1.0
eye morphology	retinal blood vessels pattern	males	2.0 %	1.0
eye morphology	retinal blood vessels pattern	both	4.0 %	1.00
eye morphology	retinal blood vessels structure	females	4.0 %	1.00
eye morphology	retinal blood vessels structure	males	2.0 %	1.0
eye morphology	retinal blood vessels structure	both	3.0 %	1.00
eye morphology	retinal pigmentation	females	12.0 %	1.0
eye morphology	retinal pigmentation	males	14.0 %	1.0
eye morphology	retinal pigmentation	both	13.0 %	1.0
eye morphology	retinal structure	females	4.0 %	1.00
eye morphology	retinal structure	males	2.0 %	1.0
eye morphology	retinal structure	both	3.0 %	1.00
eye morphology	synechia	females	4.0 %	1.0
eye morphology	synechia	males	2.0 %	1.0
eye morphology	synechia	both	3.0 %	1.00
eye morphology	vitreous	females	4.0 %	1.00
eye morphology	vitreous	males	2.0 %	1.0
eye morphology	vitreous	both	3.0 %	1.00
SHIRPA	activity body position	females	1.0 %	1.0
SHIRPA	activity body position	males	16.0 %	0.0470
SHIRPA	activity body position	both	7.0 %	0.0907
SHIRPA	aggression	females	0.0 %	1.00
SHIRPA	aggression	males	1.0 %	1.0
SHIRPA	aggression	both	1.0 %	1.0
SHIRPA	body length	females	12.0 %	0.0175
SHIRPA	body length	males	0.0 %	1.0
SHIRPA	body length	both	7.0 %	0.0205
SHIRPA	body position	females	0.0 %	1.0
SHIRPA	body position	males	17.0 %	0.00271
SHIRPA	body position	both	7.0 %	0.00384
SHIRPA	body thickness	females	1.0 %	1.0
SHIRPA	body thickness	males	0.0 %	1.0
SHIRPA	body thickness	both	0.0 %	1.0
SHIRPA	coat color abdomen	females	97.0 %	3.20e-12
SHIRPA	coat color abdomen	males	96.0 %	2.68e-9
SHIRPA	coat color abdomen	both	96.0 %	8.48e-21
SHIRPA	coat color back	females	0.0 %	1.0
SHIRPA	coat color back	males	0.0 %	1.00
SHIRPA	coat color back	both	0.0 %	1.0
SHIRPA	coat color head	females	0.0 %	1.0
SHIRPA	coat color head	males	0.0 %	1.00
SHIRPA	coat color head	both	0.0 %	1.0
SHIRPA	coat color pattern abdomen	females	1.0 %	1.0
SHIRPA	coat color pattern abdomen	males	1.0 %	1.0
SHIRPA	coat color pattern abdomen	both	1.0 %	1.0
SHIRPA	coat color pattern back	females	0.0 %	1.0
SHIRPA	coat color pattern back	males	0.0 %	1.00
SHIRPA	coat color pattern back	both	0.0 %	1.0
SHIRPA	coat color pattern head	females	0.0 %	1.0
SHIRPA	coat color pattern head	males	0.0 %	1.0
SHIRPA	coat color pattern head	both	0.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	females	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	males	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	both	2.0 %	1.0
SHIRPA	coat hair back texture appearance	females	0.0 %	1.0
SHIRPA	coat hair back texture appearance	males	0.0 %	1.0
SHIRPA	coat hair back texture appearance	both	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	females	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	males	1.0 %	1.0
SHIRPA	coat hair distribution abdomen	both	1.0 %	1.0
SHIRPA	coat hair distribution back	females	0.0 %	1.0
SHIRPA	coat hair distribution back	males	0.0 %	1.0
SHIRPA	coat hair distribution back	both	0.0 %	1.0
SHIRPA	coat hair distribution head	females	1.0 %	1.00
SHIRPA	coat hair distribution head	males	1.0 %	1.0
SHIRPA	coat hair distribution head	both	1.0 %	1.0
SHIRPA	coat hair head texture appearance	females	0.0 %	1.00
SHIRPA	coat hair head texture appearance	males	0.0 %	1.0
SHIRPA	coat hair head texture appearance	both	0.0 %	1.0
SHIRPA	contact righting	females	5.0 %	1.0
SHIRPA	contact righting	males	5.0 %	1.0
SHIRPA	contact righting	both	5.0 %	1.0
SHIRPA	ear morphology	females	0.0 %	1.0
SHIRPA	ear morphology	males	0.0 %	1.0
SHIRPA	ear morphology	both	0.0 %	1.0
SHIRPA	fat distribution	females	0.0 %	1.0
SHIRPA	fat distribution	males	0.0 %	1.0
SHIRPA	fat distribution	both	0.0 %	1.0
SHIRPA	forelimb digit number	females	0.0 %	1.00
SHIRPA	forelimb digit number	males	0.0 %	1.0
SHIRPA	forelimb digit number	both	0.0 %	1.00
SHIRPA	forelimb digit position	females	0.0 %	1.0
SHIRPA	forelimb digit position	males	0.0 %	1.0
SHIRPA	forelimb digit position	both	0.0 %	1.0
SHIRPA	forelimb digit shape	females	0.0 %	1.0
SHIRPA	forelimb digit shape	males	0.0 %	1.0
SHIRPA	forelimb digit shape	both	0.0 %	1.0
SHIRPA	forelimb digit size	females	0.0 %	1.0
SHIRPA	forelimb digit size	males	0.0 %	1.0
SHIRPA	forelimb digit size	both	0.0 %	1.0
SHIRPA	forelimb footpads	females	0.0 %	1.0
SHIRPA	forelimb footpads	males	0.0 %	1.0
SHIRPA	forelimb footpads	both	0.0 %	1.0
SHIRPA	forelimb nail length	females	0.0 %	1.0
SHIRPA	forelimb nail length	males	0.0 %	1.0
SHIRPA	forelimb nail length	both	0.0 %	1.0
SHIRPA	forelimb nail number	females	0.0 %	1.0
SHIRPA	forelimb nail number	males	0.0 %	1.0
SHIRPA	forelimb nail number	both	0.0 %	1.0
SHIRPA	forelimb nail position	females	0.0 %	1.0
SHIRPA	forelimb nail position	males	0.0 %	1.0
SHIRPA	forelimb nail position	both	0.0 %	1.0
SHIRPA	forelimb nail shape	females	0.0 %	1.0
SHIRPA	forelimb nail shape	males	0.0 %	1.0
SHIRPA	forelimb nail shape	both	0.0 %	1.0
SHIRPA	forelimbs position	females	0.0 %	1.0
SHIRPA	forelimbs position	males	0.0 %	1.0
SHIRPA	forelimbs position	both	0.0 %	1.0
SHIRPA	forelimbs shape	females	0.0 %	1.0
SHIRPA	forelimbs shape	males	0.0 %	1.0
SHIRPA	forelimbs shape	both	0.0 %	1.0
SHIRPA	forelimbs size	females	0.0 %	1.0
SHIRPA	forelimbs size	males	0.0 %	1.0
SHIRPA	forelimbs size	both	0.0 %	1.00
SHIRPA	forepaw position	females	0.0 %	1.0
SHIRPA	forepaw position	males	0.0 %	1.0
SHIRPA	forepaw position	both	0.0 %	1.0
SHIRPA	forepaw shape	females	0.0 %	1.0
SHIRPA	forepaw shape	males	0.0 %	1.0
SHIRPA	forepaw shape	both	0.0 %	1.0
SHIRPA	forepaw size	females	0.0 %	1.0
SHIRPA	forepaw size	males	0.0 %	1.0
SHIRPA	forepaw size	both	0.0 %	1.0
SHIRPA	gait (fluidity)	females	0.0 %	1.0
SHIRPA	gait (fluidity)	males	0.0 %	1.0
SHIRPA	gait (fluidity)	both	0.0 %	1.0
SHIRPA	genitalia morphology	females	0.0 %	1.00
SHIRPA	genitalia morphology	males	0.0 %	1.0
SHIRPA	genitalia morphology	both	0.0 %	1.0
SHIRPA	genitalia presence	females	0.0 %	1.0
SHIRPA	genitalia presence	males	0.0 %	1.0
SHIRPA	genitalia presence	both	0.0 %	1.0
SHIRPA	genitalia size	females	0.0 %	1.0
SHIRPA	genitalia size	males	0.0 %	1.0
SHIRPA	genitalia size	both	0.0 %	1.0
SHIRPA	head bobbing	females	0.0 %	1.0
SHIRPA	head bobbing	males	0.0 %	1.0
SHIRPA	head bobbing	both	0.0 %	1.0
SHIRPA	head morphology	females	0.0 %	1.0
SHIRPA	head morphology	males	0.0 %	1.0
SHIRPA	head morphology	both	0.0 %	1.00
SHIRPA	head size	females	0.0 %	1.0
SHIRPA	head size	males	0.0 %	1.0
SHIRPA	head size	both	0.0 %	1.00
SHIRPA	hindlimb digit number	females	1.0 %	1.00
SHIRPA	hindlimb digit number	males	0.0 %	1.0
SHIRPA	hindlimb digit number	both	0.0 %	1.00
SHIRPA	hindlimb digit position	females	0.0 %	1.0
SHIRPA	hindlimb digit position	males	0.0 %	1.0
SHIRPA	hindlimb digit position	both	0.0 %	1.0
SHIRPA	hindlimb digit shape	females	0.0 %	1.0
SHIRPA	hindlimb digit shape	males	0.0 %	1.0
SHIRPA	hindlimb digit shape	both	0.0 %	1.0
SHIRPA	hindlimb digit size	females	0.0 %	1.00
SHIRPA	hindlimb digit size	males	0.0 %	1.0
SHIRPA	hindlimb digit size	both	0.0 %	1.0
SHIRPA	hindlimb nail length	females	0.0 %	1.0
SHIRPA	hindlimb nail length	males	0.0 %	1.0
SHIRPA	hindlimb nail length	both	0.0 %	1.00
SHIRPA	hindlimb nail number	females	0.0 %	1.0
SHIRPA	hindlimb nail number	males	1.0 %	1.0
SHIRPA	hindlimb nail number	both	0.0 %	1.00
SHIRPA	hindlimb nail position	females	0.0 %	1.0
SHIRPA	hindlimb nail position	males	0.0 %	1.0
SHIRPA	hindlimb nail position	both	0.0 %	1.0
SHIRPA	hindlimb nail shape	females	0.0 %	1.0
SHIRPA	hindlimb nail shape	males	0.0 %	1.0
SHIRPA	hindlimb nail shape	both	0.0 %	1.0
SHIRPA	hindlimbs footpads	females	0.0 %	1.0
SHIRPA	hindlimbs footpads	males	0.0 %	1.0
SHIRPA	hindlimbs footpads	both	0.0 %	1.0
SHIRPA	hindlimbs position	females	0.0 %	1.0
SHIRPA	hindlimbs position	males	0.0 %	1.0
SHIRPA	hindlimbs position	both	0.0 %	1.0
SHIRPA	hindlimbs shape	females	0.0 %	1.0
SHIRPA	hindlimbs shape	males	0.0 %	1.0
SHIRPA	hindlimbs shape	both	0.0 %	1.0
SHIRPA	hindlimbs size	females	0.0 %	1.0
SHIRPA	hindlimbs size	males	0.0 %	1.0
SHIRPA	hindlimbs size	both	0.0 %	1.0
SHIRPA	hindpaw position	females	0.0 %	1.0
SHIRPA	hindpaw position	males	0.0 %	1.0
SHIRPA	hindpaw position	both	0.0 %	1.0
SHIRPA	hindpaw shape	females	0.0 %	1.0
SHIRPA	hindpaw shape	males	0.0 %	1.0
SHIRPA	hindpaw shape	both	0.0 %	1.0
SHIRPA	hindpaw size	females	0.0 %	1.0
SHIRPA	hindpaw size	males	0.0 %	1.0
SHIRPA	hindpaw size	both	0.0 %	1.0
SHIRPA	limb grasp	females	9.0 %	1.00
SHIRPA	limb grasp	males	6.0 %	1.0
SHIRPA	limb grasp	both	7.0 %	0.618
SHIRPA	lower lip morphology	females	0.0 %	1.0
SHIRPA	lower lip morphology	males	0.0 %	1.0
SHIRPA	lower lip morphology	both	0.0 %	1.0
SHIRPA	lower teeth appearance	females	0.0 %	1.0
SHIRPA	lower teeth appearance	males	0.0 %	1.00
SHIRPA	lower teeth appearance	both	0.0 %	1.0
SHIRPA	mouth morphology	females	0.0 %	1.0
SHIRPA	mouth morphology	males	0.0 %	1.0
SHIRPA	mouth morphology	both	0.0 %	1.0
SHIRPA	salivation	females	0.0 %	1.0
SHIRPA	salivation	males	0.0 %	1.0
SHIRPA	salivation	both	0.0 %	1.0
SHIRPA	skin color back paws	females	0.0 %	1.0
SHIRPA	skin color back paws	males	0.0 %	1.0
SHIRPA	skin color back paws	both	0.0 %	1.0
SHIRPA	skin color ear	females	0.0 %	1.0
SHIRPA	skin color ear	males	0.0 %	1.0
SHIRPA	skin color ear	both	0.0 %	1.0
SHIRPA	skin color front paws	females	0.0 %	1.0
SHIRPA	skin color front paws	males	0.0 %	1.0
SHIRPA	skin color front paws	both	0.0 %	1.0
SHIRPA	skin color snout	females	0.0 %	1.0
SHIRPA	skin color snout	males	0.0 %	1.0
SHIRPA	skin color snout	both	0.0 %	1.0
SHIRPA	skin color tail	females	0.0 %	1.0
SHIRPA	skin color tail	males	0.0 %	1.0
SHIRPA	skin color tail	both	0.0 %	1.0
SHIRPA	skin color whole body	females	0.0 %	1.0
SHIRPA	skin color whole body	males	0.0 %	1.0
SHIRPA	skin color whole body	both	0.0 %	1.0
SHIRPA	skin texture back paw	females	0.0 %	1.0
SHIRPA	skin texture back paw	males	0.0 %	1.0
SHIRPA	skin texture back paw	both	0.0 %	1.0
SHIRPA	skin texture ear	females	0.0 %	1.0
SHIRPA	skin texture ear	males	0.0 %	1.0
SHIRPA	skin texture ear	both	0.0 %	1.0
SHIRPA	skin texture front paws	females	0.0 %	1.0
SHIRPA	skin texture front paws	males	0.0 %	1.0
SHIRPA	skin texture front paws	both	0.0 %	1.0
SHIRPA	skin texture snout	females	0.0 %	1.0
SHIRPA	skin texture snout	males	0.0 %	1.0
SHIRPA	skin texture snout	both	0.0 %	1.0
SHIRPA	skin texture tail	females	0.0 %	1.0
SHIRPA	skin texture tail	males	0.0 %	1.0
SHIRPA	skin texture tail	both	0.0 %	1.0
SHIRPA	skin texture whole body	females	0.0 %	1.0
SHIRPA	skin texture whole body	males	0.0 %	1.0
SHIRPA	skin texture whole body	both	0.0 %	1.0
SHIRPA	snout size	females	0.0 %	1.0
SHIRPA	snout size	males	1.0 %	1.00
SHIRPA	snout size	both	0.0 %	1.0
SHIRPA	startle response	females	0.0 %	1.00
SHIRPA	startle response	males	0.0 %	1.00
SHIRPA	startle response	both	0.0 %	1.0
SHIRPA	tail curvature	females	0.0 %	1.00
SHIRPA	tail curvature	males	0.0 %	1.0
SHIRPA	tail curvature	both	0.0 %	1.00
SHIRPA	tail elevation	females	1.0 %	1.00
SHIRPA	tail elevation	males	2.0 %	1.0
SHIRPA	tail elevation	both	1.0 %	1.0
SHIRPA	tail length	females	0.0 %	1.0
SHIRPA	tail length	males	0.0 %	1.0
SHIRPA	tail length	both	0.0 %	1.0
SHIRPA	tail morphology	females	0.0 %	1.00
SHIRPA	tail morphology	males	0.0 %	1.0
SHIRPA	tail morphology	both	0.0 %	1.0
SHIRPA	tail presence	females	0.0 %	1.0
SHIRPA	tail presence	males	0.0 %	1.0
SHIRPA	tail presence	both	0.0 %	1.0
SHIRPA	tail shape	females	0.0 %	1.0
SHIRPA	tail shape	males	0.0 %	1.0
SHIRPA	tail shape	both	0.0 %	1.0
SHIRPA	tail thickness	females	0.0 %	1.0
SHIRPA	tail thickness	males	0.0 %	1.0
SHIRPA	tail thickness	both	0.0 %	1.0
SHIRPA	teeth presence	females	0.0 %	1.0
SHIRPA	teeth presence	males	0.0 %	1.0
SHIRPA	teeth presence	both	0.0 %	1.0
SHIRPA	transfer arousal	females	1.0 %	1.0
SHIRPA	transfer arousal	males	16.0 %	0.0490
SHIRPA	transfer arousal	both	6.0 %	0.0954
SHIRPA	tremor	females	0.0 %	1.0
SHIRPA	tremor	males	0.0 %	1.00
SHIRPA	tremor	both	0.0 %	1.0
SHIRPA	trunk curl	females	0.0 %	1.00
SHIRPA	trunk curl	males	0.0 %	1.0
SHIRPA	trunk curl	both	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	females	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	males	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	both	0.0 %	1.00
SHIRPA	upper lip morphology	females	0.0 %	1.0
SHIRPA	upper lip morphology	males	0.0 %	1.0
SHIRPA	upper lip morphology	both	0.0 %	1.0
SHIRPA	upper teeth appearance	females	0.0 %	1.0
SHIRPA	upper teeth appearance	males	0.0 %	1.0
SHIRPA	upper teeth appearance	both	0.0 %	1.0
SHIRPA	vibrissae appearance	females	2.0 %	1.0
SHIRPA	vibrissae appearance	males	1.0 %	1.0
SHIRPA	vibrissae appearance	both	1.0 %	1.0
SHIRPA	vibrissae presence	females	2.0 %	1.00
SHIRPA	vibrissae presence	males	1.0 %	1.0
SHIRPA	vibrissae presence	both	2.0 %	1.0
SHIRPA	vocalization	females	58.0 %	0.0000757
SHIRPA	vocalization	males	98.0 %	1.67e-7
SHIRPA	vocalization	both	76.0 %	4.33e-11

GENOTYPE CORRELATION PLOT

Correlate Rab28^em1(IMPC)J/Mmjax -/- with genotype: