MPD: JaxKOMP-EAP genotype: Stt3b<sup>em1(IMPC)J</sup>/Mmjax -/+

JaxKOMP-EAP effect sizes: Stt3b^em1(IMPC)J/Mmjax -/+ Gene Stt3b

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

In this plot, data points are the computed genotype effect size vs. C57BL/6NJ controls, for all measured numeric phenotypes in JaxKOMP-EAP

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Plot Options Group by Procedure Standard Error Show Effect Sizes RankZ

Significance Threshold p-Value Threshold Adjusted Unadjusted

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Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value

ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	0.37879	3.3514	-0.17082	0.977	0.920
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	-0.22727	4.8313	-0.029052	0.989	0.967
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	-2.9545	3.6533	-0.80181	0.806	0.504
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	2.9379	4.2443	0.36621	0.826	0.560
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	1.5436	2.5584	0.21473	0.847	0.608
body composition	body length	-0.044425	0.088550	-0.31629	0.819	0.621
body composition	body weight (at time of DXA)	-1.1376	0.77316	-0.72371	0.350	0.155
body composition	bone area, whole body scan, head excluded	-0.49239	0.19445	-1.5647	0.118	0.0186
body composition	bone mineral content of whole body scan, head excluded	-0.034709	0.015385	-1.5286	0.175	0.0339
body composition	bone mineral content to body weight ratio	-0.0014974	0.00061706	-1.5884	0.130	0.0239
body composition	bone mineral density of whole body scan, head excluded	-0.00015288	0.00088640	-0.13220	0.951	0.865
body composition	fat tissue mass of whole body scan, head excluded	1.1229	0.51548	1.5156	0.187	0.0404
body composition	fat tissue mass to body weight ratio	0.034535	0.017025	1.3830	0.198	0.0548
body composition	lean tissue mass of whole body scan, head excluded	-0.061349	0.53531	-0.27938	0.968	0.910
body composition	lean tissue mass to body weight ratio	-0.031115	0.016778	-1.5461	0.266	0.0771
body composition	percent fat, whole body scan, head excluded	3.4038	1.6780	1.4820	0.201	0.0548
body composition	ratio of soft-tissue attenuation coefficients	-0.0037831	0.0018648	-1.4850	0.204	0.0548
body composition	tissue area	0.59663	0.29884	1.6927	0.263	0.0584
body composition	total tissue mass, whole body scan, head excluded	1.0615	0.22472	1.8209	0.00350	0.000103
clinical blood chemistry	alanine transaminase (plasma ALT)	34.112	14.716	1.5997	0.309	0.0340
clinical blood chemistry	albumin (plasma Alb)	-1.2996	0.56390	-1.6069	0.229	0.0359
clinical blood chemistry	alkaline phosphatase (plasma ALP)	6.6250	3.9657	0.64673	0.319	0.114
clinical blood chemistry	aspartate transaminase (plasma AST)	39.762	12.685	1.3172	0.101	0.00682
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	-0.37854	0.20794	-1.1306	0.456	0.0874
clinical blood chemistry	blood urea nitrogen (BUN)	-0.28629	1.4120	-0.14888	0.930	0.842
clinical blood chemistry	calcium (plasma Ca)	-0.061512	0.066203	-0.094691	0.608	0.367
clinical blood chemistry	creatinine (plasma)	0.065160	0.026187	1.5730	0.138	0.0251
clinical blood chemistry	glucose (plasma GLU, no fast)	7.3333	17.144	0.57676	0.815	0.675
clinical blood chemistry	HDL cholesterol (plasma HDL)	7.9375	3.4289	1.4835	0.203	0.0342
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	-0.0097500	0.014027	-0.68031	0.780	0.497
clinical blood chemistry	phosphorus (plasma phosphate)	0.65000	0.39853	0.91888	0.362	0.122
clinical blood chemistry	total bilirubin (plasma TBIL)	0.058080	0.059083	2.4122	0.689	0.340
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	11.625	4.6657	1.5213	0.154	0.0241
clinical blood chemistry	total protein (plasma TP)	-0.37500	0.79694	-0.36175	0.815	0.644
clinical blood chemistry	triglyceride (plasma TG, no fast)	20.167	11.196	1.1930	0.322	0.0906
glucose tolerance test	amount glucose injected	11.314	1.8288	2.2914	0.433	0.102
glucose tolerance test	plasma glucose, 0min	4.4351	7.6389	0.21300	0.821	0.665
glucose tolerance test	plasma glucose, 15min	44.577	18.868	1.3121	0.588	0.255
glucose tolerance test	plasma glucose, 30min	-1.6125	17.999	0.093482	0.979	0.943
glucose tolerance test	plasma glucose, 60min	-12.438	13.234	-0.40774	0.792	0.520
glucose tolerance test	plasma glucose, 120min	-4.7875	13.358	-0.47432	0.920	0.781
grip strength	body weight (at time of grip strength test)	-1.6530	0.56831	-1.2146	0.0386	0.00791
grip strength	forelimb and hindlimb grip strength (mean of trials), average	-9.9540	8.2566	-0.45852	0.447	0.241
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	-0.52808	0.39764	-0.59368	0.392	0.198
grip strength	forelimb and hindlimb grip strength by trial, trial1	-2.6718	10.392	0.031956	0.927	0.799
grip strength	forelimb and hindlimb grip strength by trial, trial2	-12.371	8.6643	-0.54248	0.403	0.167
grip strength	forelimb and hindlimb grip strength by trial, trial3	-14.820	9.6746	-0.75996	0.382	0.140
grip strength	forelimb grip strength (mean of trials), average	-15.437	3.7138	-1.5196	0.0110	0.000381
grip strength	forelimb grip strength (mean of trials), average normalized to bw	-0.60117	0.18957	-1.2018	0.0496	0.00442
grip strength	forelimb grip strength by trial, trial1	-15.712	4.7025	-1.4132	0.0596	0.00283
grip strength	forelimb grip strength by trial, trial2	-3.5458	5.5521	-0.18550	0.807	0.530
grip strength	forelimb grip strength by trial, trial3	-21.512	4.7586	-1.8962	0.0110	0.000154
heart weight	heart weight, normalized to body weight	-0.075833	0.14475	-0.74892	0.774	0.606
heart weight	heart weight, weight	-9.7400	4.4205	-1.6180	0.163	0.0389
hematology	basophil differential (percent of total WBC)	0.088636	0.051959	1.2003	0.529	0.110
hematology	calculated hemoglobin (cHGB)	-0.0072052	0.29922	-0.30177	0.991	0.981
hematology	eosinophil differential (percent of total WBC)	0.094205	0.26739	0.35828	0.911	0.730
hematology	hematocrit (HCT)	0.93171	0.92585	0.68915	0.613	0.333
hematology	hemoglobin concentration distribution width (HDW)	0.0045455	0.030615	0.10973	0.949	0.884
hematology	large unstained cells (percent of total WBC)	0.19318	0.096887	1.2404	0.344	0.0660
hematology	lymphocyte differential (percent of total WBC)	3.1886	2.1464	1.0556	0.412	0.160
hematology	mean corpuscular hemoglobin (CHr)	-0.44804	0.097153	-2.2192	0.00609	0.000403
hematology	mean platelet volume (MPV)	0.037491	0.088353	0.080348	0.835	0.678
hematology	mean RBC corpuscular hemoglobin (MCH)	-0.55655	0.20579	-1.2129	0.172	0.0171
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	-0.66818	0.40703	-1.0423	0.453	0.123
hematology	mean RBC corpuscular volume (MCV)	-0.75892	0.27923	-1.2171	0.0873	0.0176
hematology	measured hemoglobin (mHGB)	0.098555	0.21877	-0.00068375	0.832	0.659
hematology	monocyte differential (percent of total WBC)	0.0057874	0.18940	0.23167	0.992	0.976
hematology	neutrophil differential (percent of total WBC)	-3.5182	1.9921	-1.3343	0.304	0.0992
hematology	platelet count (PLT; units per volume x 10³)	-112.24	63.320	-1.2922	0.443	0.0997
hematology	RBC corpuscular distribution width (RDW)	-0.27623	0.18591	-1.0420	0.410	0.159
hematology	RBC corpuscular hemoglobin concentration mean (CHCM)	-0.62000	0.18620	-1.5285	0.0476	0.00543
hematology	red blood cell count (RBC; per volume x 10⁶)	0.38689	0.24671	1.3404	0.392	0.141
hematology	reticulocyte count (Retic; units per volume x 10⁹)	-13.900	16.008	-0.51418	0.753	0.400
hematology	reticulocyte differential (percent of total RBC)	-0.28795	0.17606	-0.99446	0.466	0.124
hematology	white blood cell count (WBC; units per volume x 10³)	1.5606	0.79455	1.2200	0.203	0.0697
holeboard	number of hole pokes by individual hole number, 20 min test, 1	-1.3198	0.97580	-1.2607	0.685	0.190
holeboard	number of hole pokes by individual hole number, 20 min test, 2	-0.46250	0.69427	-0.61271	0.877	0.512
holeboard	number of hole pokes by individual hole number, 20 min test, 3	0.21103	0.54498	0.42703	0.937	0.702
holeboard	number of hole pokes by individual hole number, 20 min test, 4	-0.46250	0.67360	-0.38850	0.853	0.499
holeboard	number of hole pokes by individual hole number, 20 min test, 5	0.26250	0.66287	0.53898	0.938	0.696
holeboard	number of hole pokes by individual hole number, 20 min test, 6	0.15714	0.46871	0.46680	0.963	0.741
holeboard	number of hole pokes by individual hole number, 20 min test, 7	-0.3	0.33362	-0.81919	0.875	0.378
holeboard	number of hole pokes by individual hole number, 20 min test, 8	0.062500	0.44945	0.23595	0.986	0.891
holeboard	number of hole pokes by individual hole number, 20 min test, 9	-1.05	0.69540	-1.6268	0.603	0.145
holeboard	number of hole pokes by individual hole number, 20 min test, 10	0.225	0.37297	0.63571	0.917	0.552
holeboard	number of hole pokes by individual hole number, 20 min test, 11	-0.70000	0.37213	-1.8291	0.653	0.0727
holeboard	number of hole pokes by individual hole number, 20 min test, 12	-0.89449	0.52237	-1.3356	0.536	0.101
holeboard	number of hole pokes by individual hole number, 20 min test, 13	0.61250	0.93947	0.69905	0.834	0.521
holeboard	number of hole pokes by individual hole number, 20 min test, 14	0.81250	0.53017	1.2537	0.574	0.139
holeboard	number of hole pokes by individual hole number, 20 min test, 15	-0.26250	0.61701	-0.33867	0.903	0.674
holeboard	number of hole pokes by individual hole number, 20 min test, 16	-1.1950	0.86056	-1.0105	0.595	0.179
holeboard	total number of hole pokes, 20 min test	-4.1125	5.0377	-0.50093	0.680	0.423
light / dark	latency to enter dark zone, 20 min test	160.72	99.804	2.2443	0.563	0.121
light / dark	number of transitions between light and dark zones, 20 min test	-26.713	14.511	-2.2279	0.346	0.0792
light / dark	percentage of total time in dark zone, 20 min test	0.70882	5.4276	0.26958	0.966	0.897
light / dark	percentage of total time in light zone, 20 min test	-0.70882	5.4276	-0.27519	0.966	0.897
light / dark	time mobile in dark zone, 20 min test	-55.357	20.886	-2.6264	0.115	0.0143
light / dark	time mobile in light zone, 20 min test	-5.0690	21.338	-0.61539	0.911	0.814
light / dark	time spent in dark zone, 20 min test	-195.89	88.702	-2.1818	0.318	0.0379
light / dark	time spent in light zone, 20 min test	195.89	88.702	2.1818	0.318	0.0379
open field	average speed in center of arena, 20 min test	-0.42938	0.50773	-0.86754	0.734	0.406
open field	average speed in periphery of arena, 20 min test	-0.15707	0.26238	-1.1231	0.752	0.555
open field	distance traveled habituation ratio, 20 min test	1.8559	11.608	0.18430	0.951	0.874
open field	distance traveled in center of arena, 20 min test	-117.11	159.07	-1.1206	0.696	0.469
open field	distance traveled in periphery of arena, 20 min test	-128.03	276.98	-0.94236	0.810	0.648
open field	distance traveled slope, 20 min test	0.18656	11.307	0.073237	0.997	0.987
open field	distance traveled, 20 min test, 1st 5min	-100.81	118.66	-1.1181	0.644	0.404
open field	distance traveled, 20 min test, 2nd 5min	-7.8375	100.14	-0.58724	0.968	0.938
open field	distance traveled, 20 min test, 3rd 5min	-28.250	80.928	-0.75913	0.877	0.730
open field	distance traveled, 20 min test, 4th 5min	-108.3	90.200	-1.6843	0.477	0.242
open field	number of clockwise revolution episodes, 20 min test	0.32500	2.5117	-0.21799	0.968	0.898
open field	number of counter-clockwise revolution episodes, 20 min test	-1.1875	1.8450	-1.0788	0.753	0.526
open field	number of rears in 5 min bins, 20 min test, 1st 5min	0.012500	2.9989	-0.20425	1.00	0.997
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	5.2250	3.3369	1.0071	0.392	0.131
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	1.0250	3.5926	-0.079970	0.893	0.778
open field	number of rears in 5 min bins, 20 min test, 4th 5min	2.175	4.3820	0.15298	0.814	0.624
open field	percentage of total time in center of arena, 20 min test	-0.23137	4.2238	-0.25862	0.986	0.957
open field	percentage of total time in center of arena, slope, 20 min test	-2.9955	1.6156	-1.3885	0.498	0.0766
open field	percentage of total time in center, habituation ratio, 20 min test	-2.994	1.7753	-1.3542	0.545	0.105
open field	percentage of total time in corners of arena, 20 min test	2.8063	7.0127	0.81401	0.878	0.693
open field	percentage of total time in corners, habituation ratio, 20 min test	2.8186	2.3643	0.95287	0.748	0.246
open field	percentage of total time in corners, slope, 20 min test	3.0502	2.2722	1.0885	0.674	0.193
open field	permanence time in center of arena, 20 min test	-2.7662	50.688	-0.25584	0.985	0.957
open field	permanence time in corners of arena, 20 min test	33.679	84.151	0.81775	0.879	0.693
open field	permanence time in periphery of arena, 20 min test	2.8125	50.673	0.25584	0.986	0.956
open field	total distance traveled, 20 min test	-245.14	349.37	-1.1644	0.693	0.490
open field	total number of rears, 20 min test	8.4375	13.017	0.24753	0.732	0.523
open field	whole arena average speed, 20 min test	-0.20550	0.29103	-1.1671	0.692	0.487
open field	whole arena resting time, 20 min test	38.434	36.400	1.6162	0.509	0.302
open field	whole arena time spent mobile, 20 min test	-38.672	36.362	-1.8809	0.512	0.299
open field	whole arena time spent vertical, 20 min test	4.9838	10.783	0.29629	0.858	0.648
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	-0.63538	1.7226	-0.093712	0.896	0.716
startle / PPI	average baseline movement during background noise	4.8146	2.1522	2.1826	0.478	0.0357
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	-0.11214	0.087860	-1.1200	0.580	0.215
startle / PPI	average of each corrected percent pre-pulse inhibition value	-0.14216	0.084493	-1.4556	0.422	0.107
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-15.486	11.435	-1.5564	0.850	0.189
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-5.2230	10.671	-0.54818	0.860	0.629
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-7.9128	9.0518	-0.84722	0.690	0.391
startle / PPI	average startle response to full pulse (120 dB)	-40.556	37.048	-0.56454	0.530	0.285
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	23.016	49.010	0.66966	0.816	0.643
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-58.363	41.268	-0.91328	0.378	0.171
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-28.342	36.501	-0.49520	0.644	0.445
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	-0.82500	1.5541	-0.54168	0.913	0.601
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	1.3646	1.7174	0.80776	0.864	0.435
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	5.0021	3.2783	1.6103	0.574	0.141
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.18686	0.12219	-1.5611	0.809	0.140
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.037896	0.11205	-0.42253	0.909	0.738
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-0.067538	0.10420	-0.69934	0.753	0.524
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	-43.681	36.393	-0.59772	0.479	0.242
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	24.328	49.764	0.68198	0.805	0.630
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	-59.727	40.677	-0.92827	0.358	0.156
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	-33.344	36.570	-0.58271	0.583	0.371
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.14156	0.11921	-1.1466	0.841	0.247
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.027515	0.11470	-0.30319	0.922	0.813
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-0.056347	0.10830	-0.59057	0.807	0.608
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	-170.51	129.78	-0.65223	0.428	0.202
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	47.567	170.99	0.44203	0.897	0.783
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	-245.72	143.98	-1.0518	0.275	0.101
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	-140.99	137.36	-0.69085	0.530	0.315
startle / PPI	maximum baseline movement during background noise	9.6063	5.6277	1.9032	0.572	0.102
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-12.487	11.549	-1.1602	0.888	0.291
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-3.6414	11.076	-0.39462	0.904	0.745
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-6.6093	9.7782	-0.71597	0.770	0.506
startle / PPI	maximum startle response to full pulse (120 dB)	-165.35	131.37	-0.62815	0.454	0.221
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	44.832	169.33	0.42356	0.901	0.794
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-242.22	145.44	-1.0301	0.291	0.109
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-129.15	137.29	-0.62474	0.571	0.357
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	-2.0167	3.3844	-0.55144	0.880	0.557
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	3.5	3.5251	0.87360	0.782	0.331
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	11.848	8.2589	1.5066	0.535	0.165

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

In this plot, data points are the computed genotype effect % vs. C57BL/6NJ controls, for all measured categorical phenotypes in JaxKOMP-EAP

Dimensions Width: × Height: px

Plot Options Group by Procedure

Include Sexes Data Both Females Males

Significance Threshold p-Value Threshold

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Procedure	JaxKOMP-EAP Trait	Sex	Trait Effect	P-value

eye morphology	anterior chamber depth	females	1.0 %	1.0
eye morphology	anterior chamber depth	males	0.0 %	1.0
eye morphology	anterior chamber depth	both	1.0 %	1.0
eye morphology	bulging eye	females	1.0 %	1.0
eye morphology	bulging eye	males	0.0 %	1.0
eye morphology	bulging eye	both	1.0 %	1.00
eye morphology	cornea	females	4.0 %	1.0
eye morphology	cornea	males	2.0 %	1.0
eye morphology	cornea	both	3.0 %	1.00
eye morphology	cornea opacity	females	9.0 %	0.359
eye morphology	cornea opacity	males	1.0 %	1.0
eye morphology	cornea opacity	both	4.0 %	0.428
eye morphology	cornea vascularization	females	3.0 %	1.0
eye morphology	cornea vascularization	males	1.0 %	1.0
eye morphology	cornea vascularization	both	2.0 %	1.00
eye morphology	corneal deposits	females	2.0 %	1.0
eye morphology	corneal deposits	males	1.0 %	1.0
eye morphology	corneal deposits	both	1.0 %	1.00
eye morphology	corneal mineralization	females	2.0 %	1.0
eye morphology	corneal mineralization	males	1.0 %	1.0
eye morphology	corneal mineralization	both	1.0 %	1.00
eye morphology	corneal scleralization	females	3.0 %	1.00
eye morphology	corneal scleralization	males	1.0 %	1.0
eye morphology	corneal scleralization	both	2.0 %	1.00
eye morphology	corneal ulcer	females	1.0 %	1.0
eye morphology	corneal ulcer	males	1.0 %	1.0
eye morphology	corneal ulcer	both	1.0 %	1.00
eye morphology	eye closure	females	1.0 %	1.00
eye morphology	eye closure	males	0.0 %	1.0
eye morphology	eye closure	both	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	females	2.0 %	1.00
eye morphology	eye hemorrhage or blood presence	males	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	both	1.0 %	1.00
eye morphology	eyelid morphology	females	1.0 %	1.0
eye morphology	eyelid morphology	males	0.0 %	1.0
eye morphology	eyelid morphology	both	1.0 %	1.0
eye morphology	eyes (present, absent)	females	1.0 %	1.0
eye morphology	eyes (present, absent)	males	0.0 %	1.0
eye morphology	eyes (present, absent)	both	0.0 %	1.0
eye morphology	fusion between cornea and lens	females	4.0 %	1.00
eye morphology	fusion between cornea and lens	males	2.0 %	1.0
eye morphology	fusion between cornea and lens	both	3.0 %	1.00
eye morphology	iris pigmentation	females	2.0 %	1.0
eye morphology	iris pigmentation	males	1.0 %	1.0
eye morphology	iris pigmentation	both	2.0 %	1.00
eye morphology	iris transillumination	females	2.0 %	1.00
eye morphology	iris transillumination	males	1.0 %	1.0
eye morphology	iris transillumination	both	1.0 %	1.00
eye morphology	irispupil	females	4.0 %	1.00
eye morphology	irispupil	males	3.0 %	1.0
eye morphology	irispupil	both	3.0 %	1.00
eye morphology	lacrimation	females	3.0 %	1.0
eye morphology	lacrimation	males	2.0 %	1.0
eye morphology	lacrimation	both	3.0 %	1.0
eye morphology	lens	females	10.0 %	1.00
eye morphology	lens	males	8.0 %	1.0
eye morphology	lens	both	9.0 %	1.0
eye morphology	lens opacity	females	9.0 %	0.531
eye morphology	lens opacity	males	6.0 %	1.0
eye morphology	lens opacity	both	3.0 %	0.703
eye morphology	narrow eye opening	females	2.0 %	1.0
eye morphology	narrow eye opening	males	1.0 %	1.0
eye morphology	narrow eye opening	both	1.0 %	1.0
eye morphology	optic disc	females	4.0 %	1.00
eye morphology	optic disc	males	2.0 %	1.0
eye morphology	optic disc	both	3.0 %	1.00
eye morphology	persistence of hyaloid vascular system	females	12.0 %	0.218
eye morphology	persistence of hyaloid vascular system	males	5.0 %	1.0
eye morphology	persistence of hyaloid vascular system	both	6.0 %	0.332
eye morphology	pupil dilation	females	2.0 %	1.0
eye morphology	pupil dilation	males	1.0 %	1.0
eye morphology	pupil dilation	both	2.0 %	1.0
eye morphology	pupil light response	females	2.0 %	1.00
eye morphology	pupil light response	males	1.0 %	1.0
eye morphology	pupil light response	both	2.0 %	1.00
eye morphology	pupil position	females	4.0 %	1.00
eye morphology	pupil position	males	3.0 %	1.0
eye morphology	pupil position	both	4.0 %	1.00
eye morphology	pupil shape	females	3.0 %	1.00
eye morphology	pupil shape	males	2.0 %	1.0
eye morphology	pupil shape	both	3.0 %	1.00
eye morphology	retina	females	10.0 %	1.0
eye morphology	retina	males	16.0 %	1.0
eye morphology	retina	both	13.0 %	1.0
eye morphology	retinal blood vessels	females	4.0 %	1.0
eye morphology	retinal blood vessels	males	2.0 %	1.0
eye morphology	retinal blood vessels	both	3.0 %	1.0
eye morphology	retinal blood vessels pattern	females	5.0 %	1.0
eye morphology	retinal blood vessels pattern	males	2.0 %	1.0
eye morphology	retinal blood vessels pattern	both	4.0 %	1.00
eye morphology	retinal blood vessels structure	females	4.0 %	1.00
eye morphology	retinal blood vessels structure	males	2.0 %	1.0
eye morphology	retinal blood vessels structure	both	3.0 %	1.00
eye morphology	retinal pigmentation	females	12.0 %	1.0
eye morphology	retinal pigmentation	males	14.0 %	1.0
eye morphology	retinal pigmentation	both	13.0 %	1.0
eye morphology	retinal structure	females	4.0 %	1.00
eye morphology	retinal structure	males	2.0 %	1.0
eye morphology	retinal structure	both	3.0 %	1.00
eye morphology	synechia	females	4.0 %	1.0
eye morphology	synechia	males	2.0 %	1.0
eye morphology	synechia	both	3.0 %	1.00
eye morphology	vitreous	females	4.0 %	1.00
eye morphology	vitreous	males	2.0 %	1.0
eye morphology	vitreous	both	3.0 %	1.00
SHIRPA	activity body position	females	12.0 %	0.0440
SHIRPA	activity body position	males	24.0 %	0.00385
SHIRPA	activity body position	both	17.0 %	0.00128
SHIRPA	aggression	females	0.0 %	1.00
SHIRPA	aggression	males	24.0 %	0.00128
SHIRPA	aggression	both	12.0 %	0.00384
SHIRPA	body length	females	12.0 %	0.0175
SHIRPA	body length	males	0.0 %	1.00
SHIRPA	body length	both	6.0 %	0.0234
SHIRPA	body position	females	12.0 %	0.00301
SHIRPA	body position	males	1.0 %	1.0
SHIRPA	body position	both	6.0 %	0.00460
SHIRPA	body thickness	females	12.0 %	0.0517
SHIRPA	body thickness	males	0.0 %	1.0
SHIRPA	body thickness	both	6.0 %	0.0796
SHIRPA	coat color abdomen	females	97.0 %	3.20e-12
SHIRPA	coat color abdomen	males	96.0 %	4.02e-12
SHIRPA	coat color abdomen	both	96.0 %	1.24e-23
SHIRPA	coat color back	females	0.0 %	1.0
SHIRPA	coat color back	males	0.0 %	1.00
SHIRPA	coat color back	both	0.0 %	1.00
SHIRPA	coat color head	females	0.0 %	1.0
SHIRPA	coat color head	males	0.0 %	1.00
SHIRPA	coat color head	both	0.0 %	1.0
SHIRPA	coat color pattern abdomen	females	1.0 %	1.0
SHIRPA	coat color pattern abdomen	males	1.0 %	1.0
SHIRPA	coat color pattern abdomen	both	1.0 %	1.0
SHIRPA	coat color pattern back	females	0.0 %	1.0
SHIRPA	coat color pattern back	males	0.0 %	1.00
SHIRPA	coat color pattern back	both	0.0 %	1.0
SHIRPA	coat color pattern head	females	0.0 %	1.0
SHIRPA	coat color pattern head	males	0.0 %	1.0
SHIRPA	coat color pattern head	both	0.0 %	1.00
SHIRPA	coat hair abdomen texture appearance	females	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	males	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	both	2.0 %	1.0
SHIRPA	coat hair back texture appearance	females	0.0 %	1.0
SHIRPA	coat hair back texture appearance	males	0.0 %	1.0
SHIRPA	coat hair back texture appearance	both	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	females	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	males	1.0 %	1.00
SHIRPA	coat hair distribution abdomen	both	1.0 %	1.00
SHIRPA	coat hair distribution back	females	0.0 %	1.0
SHIRPA	coat hair distribution back	males	0.0 %	1.0
SHIRPA	coat hair distribution back	both	0.0 %	1.0
SHIRPA	coat hair distribution head	females	1.0 %	1.00
SHIRPA	coat hair distribution head	males	1.0 %	1.0
SHIRPA	coat hair distribution head	both	1.0 %	1.0
SHIRPA	coat hair head texture appearance	females	0.0 %	1.00
SHIRPA	coat hair head texture appearance	males	0.0 %	1.0
SHIRPA	coat hair head texture appearance	both	0.0 %	1.0
SHIRPA	contact righting	females	5.0 %	1.0
SHIRPA	contact righting	males	5.0 %	1.00
SHIRPA	contact righting	both	5.0 %	1.00
SHIRPA	ear morphology	females	0.0 %	1.0
SHIRPA	ear morphology	males	0.0 %	1.0
SHIRPA	ear morphology	both	0.0 %	1.0
SHIRPA	fat distribution	females	0.0 %	1.0
SHIRPA	fat distribution	males	0.0 %	1.0
SHIRPA	fat distribution	both	0.0 %	1.00
SHIRPA	forelimb digit number	females	0.0 %	1.00
SHIRPA	forelimb digit number	males	0.0 %	1.0
SHIRPA	forelimb digit number	both	0.0 %	1.00
SHIRPA	forelimb digit position	females	0.0 %	1.0
SHIRPA	forelimb digit position	males	0.0 %	1.0
SHIRPA	forelimb digit position	both	0.0 %	1.0
SHIRPA	forelimb digit shape	females	0.0 %	1.0
SHIRPA	forelimb digit shape	males	0.0 %	1.0
SHIRPA	forelimb digit shape	both	0.0 %	1.0
SHIRPA	forelimb digit size	females	0.0 %	1.0
SHIRPA	forelimb digit size	males	0.0 %	1.0
SHIRPA	forelimb digit size	both	0.0 %	1.0
SHIRPA	forelimb footpads	females	0.0 %	1.0
SHIRPA	forelimb footpads	males	0.0 %	1.0
SHIRPA	forelimb footpads	both	0.0 %	1.0
SHIRPA	forelimb nail length	females	0.0 %	1.0
SHIRPA	forelimb nail length	males	0.0 %	1.0
SHIRPA	forelimb nail length	both	0.0 %	1.0
SHIRPA	forelimb nail number	females	0.0 %	1.0
SHIRPA	forelimb nail number	males	0.0 %	1.0
SHIRPA	forelimb nail number	both	0.0 %	1.0
SHIRPA	forelimb nail position	females	0.0 %	1.0
SHIRPA	forelimb nail position	males	0.0 %	1.0
SHIRPA	forelimb nail position	both	0.0 %	1.0
SHIRPA	forelimb nail shape	females	0.0 %	1.0
SHIRPA	forelimb nail shape	males	0.0 %	1.0
SHIRPA	forelimb nail shape	both	0.0 %	1.0
SHIRPA	forelimbs position	females	0.0 %	1.0
SHIRPA	forelimbs position	males	0.0 %	1.0
SHIRPA	forelimbs position	both	0.0 %	1.0
SHIRPA	forelimbs shape	females	0.0 %	1.0
SHIRPA	forelimbs shape	males	0.0 %	1.0
SHIRPA	forelimbs shape	both	0.0 %	1.0
SHIRPA	forelimbs size	females	0.0 %	1.0
SHIRPA	forelimbs size	males	0.0 %	1.0
SHIRPA	forelimbs size	both	0.0 %	1.0
SHIRPA	forepaw position	females	0.0 %	1.0
SHIRPA	forepaw position	males	0.0 %	1.0
SHIRPA	forepaw position	both	0.0 %	1.0
SHIRPA	forepaw shape	females	0.0 %	1.0
SHIRPA	forepaw shape	males	0.0 %	1.0
SHIRPA	forepaw shape	both	0.0 %	1.0
SHIRPA	forepaw size	females	0.0 %	1.0
SHIRPA	forepaw size	males	0.0 %	1.0
SHIRPA	forepaw size	both	0.0 %	1.0
SHIRPA	gait (fluidity)	females	0.0 %	1.0
SHIRPA	gait (fluidity)	males	0.0 %	1.00
SHIRPA	gait (fluidity)	both	0.0 %	1.00
SHIRPA	genitalia morphology	females	0.0 %	1.00
SHIRPA	genitalia morphology	males	0.0 %	1.0
SHIRPA	genitalia morphology	both	0.0 %	1.00
SHIRPA	genitalia presence	females	0.0 %	1.0
SHIRPA	genitalia presence	males	0.0 %	1.0
SHIRPA	genitalia presence	both	0.0 %	1.0
SHIRPA	genitalia size	females	0.0 %	1.0
SHIRPA	genitalia size	males	0.0 %	1.0
SHIRPA	genitalia size	both	0.0 %	1.0
SHIRPA	head bobbing	females	0.0 %	1.0
SHIRPA	head bobbing	males	0.0 %	1.0
SHIRPA	head bobbing	both	0.0 %	1.0
SHIRPA	head morphology	females	0.0 %	1.0
SHIRPA	head morphology	males	0.0 %	1.00
SHIRPA	head morphology	both	0.0 %	1.0
SHIRPA	head size	females	0.0 %	1.0
SHIRPA	head size	males	0.0 %	1.0
SHIRPA	head size	both	0.0 %	1.00
SHIRPA	hindlimb digit number	females	1.0 %	1.00
SHIRPA	hindlimb digit number	males	0.0 %	1.0
SHIRPA	hindlimb digit number	both	0.0 %	1.00
SHIRPA	hindlimb digit position	females	0.0 %	1.0
SHIRPA	hindlimb digit position	males	0.0 %	1.0
SHIRPA	hindlimb digit position	both	0.0 %	1.0
SHIRPA	hindlimb digit shape	females	0.0 %	1.0
SHIRPA	hindlimb digit shape	males	0.0 %	1.0
SHIRPA	hindlimb digit shape	both	0.0 %	1.0
SHIRPA	hindlimb digit size	females	0.0 %	1.00
SHIRPA	hindlimb digit size	males	0.0 %	1.0
SHIRPA	hindlimb digit size	both	0.0 %	1.00
SHIRPA	hindlimb nail length	females	0.0 %	1.0
SHIRPA	hindlimb nail length	males	0.0 %	1.0
SHIRPA	hindlimb nail length	both	0.0 %	1.00
SHIRPA	hindlimb nail number	females	0.0 %	1.0
SHIRPA	hindlimb nail number	males	1.0 %	1.0
SHIRPA	hindlimb nail number	both	0.0 %	1.00
SHIRPA	hindlimb nail position	females	0.0 %	1.0
SHIRPA	hindlimb nail position	males	0.0 %	1.0
SHIRPA	hindlimb nail position	both	0.0 %	1.0
SHIRPA	hindlimb nail shape	females	0.0 %	1.0
SHIRPA	hindlimb nail shape	males	0.0 %	1.0
SHIRPA	hindlimb nail shape	both	0.0 %	1.0
SHIRPA	hindlimbs footpads	females	0.0 %	1.0
SHIRPA	hindlimbs footpads	males	0.0 %	1.0
SHIRPA	hindlimbs footpads	both	0.0 %	1.0
SHIRPA	hindlimbs position	females	0.0 %	1.0
SHIRPA	hindlimbs position	males	0.0 %	1.0
SHIRPA	hindlimbs position	both	0.0 %	1.0
SHIRPA	hindlimbs shape	females	0.0 %	1.0
SHIRPA	hindlimbs shape	males	0.0 %	1.0
SHIRPA	hindlimbs shape	both	0.0 %	1.0
SHIRPA	hindlimbs size	females	0.0 %	1.0
SHIRPA	hindlimbs size	males	0.0 %	1.0
SHIRPA	hindlimbs size	both	0.0 %	1.0
SHIRPA	hindpaw position	females	0.0 %	1.0
SHIRPA	hindpaw position	males	0.0 %	1.0
SHIRPA	hindpaw position	both	0.0 %	1.0
SHIRPA	hindpaw shape	females	0.0 %	1.0
SHIRPA	hindpaw shape	males	0.0 %	1.0
SHIRPA	hindpaw shape	both	0.0 %	1.0
SHIRPA	hindpaw size	females	0.0 %	1.0
SHIRPA	hindpaw size	males	0.0 %	1.0
SHIRPA	hindpaw size	both	0.0 %	1.0
SHIRPA	limb grasp	females	16.0 %	0.154
SHIRPA	limb grasp	males	19.0 %	0.0730
SHIRPA	limb grasp	both	18.0 %	0.0254
SHIRPA	lower lip morphology	females	0.0 %	1.0
SHIRPA	lower lip morphology	males	0.0 %	1.0
SHIRPA	lower lip morphology	both	0.0 %	1.0
SHIRPA	lower teeth appearance	females	0.0 %	1.0
SHIRPA	lower teeth appearance	males	0.0 %	1.00
SHIRPA	lower teeth appearance	both	0.0 %	1.00
SHIRPA	mouth morphology	females	0.0 %	1.0
SHIRPA	mouth morphology	males	0.0 %	1.00
SHIRPA	mouth morphology	both	0.0 %	1.00
SHIRPA	salivation	females	0.0 %	1.0
SHIRPA	salivation	males	0.0 %	1.0
SHIRPA	salivation	both	0.0 %	1.0
SHIRPA	skin color back paws	females	0.0 %	1.0
SHIRPA	skin color back paws	males	0.0 %	1.0
SHIRPA	skin color back paws	both	0.0 %	1.0
SHIRPA	skin color ear	females	0.0 %	1.0
SHIRPA	skin color ear	males	0.0 %	1.0
SHIRPA	skin color ear	both	0.0 %	1.0
SHIRPA	skin color front paws	females	0.0 %	1.0
SHIRPA	skin color front paws	males	0.0 %	1.0
SHIRPA	skin color front paws	both	0.0 %	1.0
SHIRPA	skin color snout	females	0.0 %	1.0
SHIRPA	skin color snout	males	0.0 %	1.0
SHIRPA	skin color snout	both	0.0 %	1.0
SHIRPA	skin color tail	females	0.0 %	1.0
SHIRPA	skin color tail	males	0.0 %	1.0
SHIRPA	skin color tail	both	0.0 %	1.0
SHIRPA	skin color whole body	females	0.0 %	1.0
SHIRPA	skin color whole body	males	0.0 %	1.0
SHIRPA	skin color whole body	both	0.0 %	1.0
SHIRPA	skin texture back paw	females	0.0 %	1.0
SHIRPA	skin texture back paw	males	0.0 %	1.0
SHIRPA	skin texture back paw	both	0.0 %	1.0
SHIRPA	skin texture ear	females	0.0 %	1.0
SHIRPA	skin texture ear	males	0.0 %	1.0
SHIRPA	skin texture ear	both	0.0 %	1.0
SHIRPA	skin texture front paws	females	0.0 %	1.0
SHIRPA	skin texture front paws	males	0.0 %	1.0
SHIRPA	skin texture front paws	both	0.0 %	1.0
SHIRPA	skin texture snout	females	0.0 %	1.0
SHIRPA	skin texture snout	males	0.0 %	1.0
SHIRPA	skin texture snout	both	0.0 %	1.0
SHIRPA	skin texture tail	females	0.0 %	1.0
SHIRPA	skin texture tail	males	0.0 %	1.0
SHIRPA	skin texture tail	both	0.0 %	1.0
SHIRPA	skin texture whole body	females	0.0 %	1.0
SHIRPA	skin texture whole body	males	0.0 %	1.00
SHIRPA	skin texture whole body	both	0.0 %	1.00
SHIRPA	snout size	females	0.0 %	1.0
SHIRPA	snout size	males	1.0 %	1.0
SHIRPA	snout size	both	0.0 %	1.0
SHIRPA	startle response	females	0.0 %	1.00
SHIRPA	startle response	males	0.0 %	1.00
SHIRPA	startle response	both	0.0 %	1.00
SHIRPA	tail curvature	females	0.0 %	1.00
SHIRPA	tail curvature	males	0.0 %	1.0
SHIRPA	tail curvature	both	0.0 %	1.0
SHIRPA	tail elevation	females	1.0 %	1.00
SHIRPA	tail elevation	males	2.0 %	1.0
SHIRPA	tail elevation	both	1.0 %	1.0
SHIRPA	tail length	females	0.0 %	1.0
SHIRPA	tail length	males	0.0 %	1.0
SHIRPA	tail length	both	0.0 %	1.00
SHIRPA	tail morphology	females	0.0 %	1.00
SHIRPA	tail morphology	males	0.0 %	1.0
SHIRPA	tail morphology	both	0.0 %	1.00
SHIRPA	tail presence	females	0.0 %	1.0
SHIRPA	tail presence	males	0.0 %	1.0
SHIRPA	tail presence	both	0.0 %	1.0
SHIRPA	tail shape	females	0.0 %	1.0
SHIRPA	tail shape	males	0.0 %	1.0
SHIRPA	tail shape	both	0.0 %	1.00
SHIRPA	tail thickness	females	0.0 %	1.0
SHIRPA	tail thickness	males	0.0 %	1.0
SHIRPA	tail thickness	both	0.0 %	1.0
SHIRPA	teeth presence	females	0.0 %	1.0
SHIRPA	teeth presence	males	0.0 %	1.00
SHIRPA	teeth presence	both	0.0 %	1.00
SHIRPA	transfer arousal	females	12.0 %	0.00608
SHIRPA	transfer arousal	males	25.0 %	0.0000195
SHIRPA	transfer arousal	both	17.0 %	1.33e-7
SHIRPA	tremor	females	0.0 %	1.0
SHIRPA	tremor	males	0.0 %	1.0
SHIRPA	tremor	both	0.0 %	1.00
SHIRPA	trunk curl	females	0.0 %	1.00
SHIRPA	trunk curl	males	0.0 %	1.0
SHIRPA	trunk curl	both	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	females	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	males	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	both	0.0 %	1.00
SHIRPA	upper lip morphology	females	0.0 %	1.0
SHIRPA	upper lip morphology	males	0.0 %	1.0
SHIRPA	upper lip morphology	both	0.0 %	1.0
SHIRPA	upper teeth appearance	females	0.0 %	1.0
SHIRPA	upper teeth appearance	males	0.0 %	1.0
SHIRPA	upper teeth appearance	both	0.0 %	1.00
SHIRPA	vibrissae appearance	females	2.0 %	1.0
SHIRPA	vibrissae appearance	males	1.0 %	1.0
SHIRPA	vibrissae appearance	both	1.0 %	1.0
SHIRPA	vibrissae presence	females	2.0 %	1.00
SHIRPA	vibrissae presence	males	1.0 %	1.0
SHIRPA	vibrissae presence	both	2.0 %	1.0

GENOTYPE CORRELATION PLOT

Correlate Stt3b^em1(IMPC)J/Mmjax -/+ with genotype: