MPD: JaxKOMP-EAP genotype: Ccdc170<sup>em1(IMPC)J</sup>/Mmjax -/-

JaxKOMP-EAP effect sizes: Ccdc170^em1(IMPC)J/Mmjax -/- Gene Ccdc170

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

In this plot, data points are the computed genotype effect size vs. C57BL/6NJ controls, for all measured numeric phenotypes in JaxKOMP-EAP

Dimensions Width: × Height: px

Plot Options Group by Procedure Standard Error Show Effect Sizes RankZ

Significance Threshold p-Value Threshold Adjusted Unadjusted

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Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value

ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	4.9439	3.5141	1.0871	0.610	0.181
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	9.4516	3.3922	1.6048	0.261	0.0146
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	7.3214	5.4073	1.0857	0.557	0.197
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	4.2692	4.8824	0.57565	0.742	0.398
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	13.750	6.0003	1.9204	0.294	0.0380
body composition	body length	0.10003	0.070576	1.4237	0.458	0.173
body composition	body weight (at time of DXA)	-0.45592	0.92379	-0.26153	0.796	0.627
body composition	bone area, whole body scan, head excluded	0.25665	0.21024	1.2991	0.508	0.237
body composition	bone mineral content of whole body scan, head excluded	0.015962	0.013913	1.0468	0.551	0.266
body composition	bone mineral content to body weight ratio	0.00043207	0.00052163	0.76837	0.668	0.418
body composition	bone mineral density of whole body scan, head excluded	0.00077608	0.00057525	0.89540	0.486	0.193
body composition	fat tissue mass of whole body scan, head excluded	-0.43700	0.44122	-0.80182	0.594	0.334
body composition	fat tissue mass to body weight ratio	-0.029479	0.016709	-1.3055	0.267	0.0930
body composition	lean tissue mass of whole body scan, head excluded	-0.17757	0.32305	-0.54456	0.816	0.589
body composition	lean tissue mass to body weight ratio	-0.010856	0.0094306	-0.65194	0.525	0.264
body composition	percent fat, whole body scan, head excluded	-2.5668	1.5987	-1.2293	0.324	0.124
body composition	ratio of soft-tissue attenuation coefficients	0.0028525	0.0017775	1.2310	0.324	0.124
body composition	tissue area	-0.30782	0.19384	-0.84905	0.397	0.129
body composition	total tissue mass, whole body scan, head excluded	-0.26308	0.26985	-0.86560	0.595	0.342
clinical blood chemistry	alanine transaminase (plasma ALT)	-3.9139	5.1096	-0.37945	0.776	0.453
clinical blood chemistry	albumin (plasma Alb)	0.33740	0.46148	0.50390	0.760	0.474
clinical blood chemistry	alkaline phosphatase (plasma ALP)	-0.47447	3.8498	-0.60877	0.957	0.903
clinical blood chemistry	aspartate transaminase (plasma AST)	-5.1057	5.8518	-0.25364	0.699	0.394
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	0.016220	0.12330	0.072452	0.970	0.897
clinical blood chemistry	blood urea nitrogen (BUN)	1.5976	1.5241	0.61841	0.578	0.307
clinical blood chemistry	calcium (plasma Ca)	-0.037681	0.078984	0.073288	0.796	0.639
clinical blood chemistry	creatinine (plasma)	0.025781	0.014755	0.76380	0.292	0.0959
clinical blood chemistry	glucose (plasma GLU, no fast)	-3.6220	18.277	0.15415	0.915	0.845
clinical blood chemistry	HDL cholesterol (plasma HDL)	4.9521	3.5326	0.83317	0.462	0.177
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	0.030437	0.012223	1.4479	0.184	0.0217
clinical blood chemistry	phosphorus (plasma phosphate)	-0.45097	0.46738	-0.77024	0.637	0.346
clinical blood chemistry	total bilirubin (plasma TBIL)	-0.017471	0.0088855	-1.2065	0.305	0.0640
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	-0.059454	3.5329	-0.25658	0.995	0.987
clinical blood chemistry	total protein (plasma TP)	1.1905	0.55601	0.88345	0.230	0.0448
clinical blood chemistry	triglyceride (plasma TG, no fast)	-8.9096	14.229	-0.28718	0.772	0.539
EKG	duration of PQ interval	-0.27764	0.83638	-0.14966	0.939	0.741
EKG	duration of PR interval	-0.26478	0.82114	-0.17416	0.938	0.749
EKG	duration of QRS interval	-0.041686	0.23442	-0.26084	0.988	0.860
EKG	duration of QT interval	-0.26661	0.61723	-0.090798	0.922	0.668
EKG	duration of QTC interval, calculated by dividing QT interval by square root of preceding RR interval	-0.22937	0.60715	-0.19261	0.956	0.707
EKG	duration of RR interval	-0.29951	1.3845	0.088775	0.938	0.830
EKG	duration of ST interval	-0.21864	0.53276	-0.022167	0.931	0.683
EKG	heart rate coefficient of variation (signal intensity)	-0.29430	0.99899	-0.13948	0.968	0.770
EKG	heart rate variability, mean of differences between sequential beats; beats per min	-1.7240	7.0867	-0.094846	0.969	0.809
EKG	heart rate, beats per min	2.6961	11.346	-0.10201	0.936	0.813
EKG	mean R amplitude, mean amplitude of signal measured from isoelectric line to peak of QRS	-0.025927	0.057432	-0.32953	0.891	0.654
EKG	mean SR amplitude, mean amplitude of signal measured from signal minimum line to peak of QRS	-0.026041	0.095580	-0.22678	0.922	0.786
EKG	number of signals	0.48567	6.9311	0.066543	0.993	0.944
EKG	proportion of number pairs of successive beat-to-beat intervals that exceed 50 ms	-3.0818	4.5754	-0.49337	0.866	0.504
EKG	QT dispersion, measured as inter-lead variability of QT intervals	2.9380	2.0652	0.86423	0.865	0.161
EKG	QTc dispersion, calculated as rate-corrected QT dispersion	2.9265	2.3705	0.77676	0.863	0.223
EKG	root mean square of successive differences of neighboring RR intervals	0.80781	1.3044	0.55517	0.902	0.539
glucose tolerance test	amount glucose injected	-1.9505	2.3060	-0.21828	0.742	0.405
glucose tolerance test	plasma glucose, 0min	-0.32681	4.7103	-0.27239	0.976	0.945
glucose tolerance test	plasma glucose, 15min	-1.9239	19.549	0.052188	0.971	0.922
glucose tolerance test	plasma glucose, 30min	-10.530	12.793	-0.19198	0.725	0.417
glucose tolerance test	plasma glucose, 60min	-21.903	12.056	-0.81301	0.334	0.0796
glucose tolerance test	plasma glucose, 120min	-5.4955	8.9775	-0.52409	0.788	0.545
grip strength	body weight (at time of grip strength test)	-0.11587	0.41883	0.098801	0.877	0.783
grip strength	forelimb and hindlimb grip strength (mean of trials), average	-6.2272	5.3159	-0.22108	0.454	0.247
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	-0.40494	0.25610	-0.39331	0.291	0.120
grip strength	forelimb and hindlimb grip strength by trial, trial1	1.8042	6.2280	0.34974	0.910	0.773
grip strength	forelimb and hindlimb grip strength by trial, trial2	-7.5818	7.5349	-0.24197	0.576	0.319
grip strength	forelimb and hindlimb grip strength by trial, trial3	-13.559	6.3763	-0.67358	0.188	0.0385
grip strength	forelimb grip strength (mean of trials), average	-0.53932	3.2867	0.19289	0.951	0.870
grip strength	forelimb grip strength (mean of trials), average normalized to bw	-0.089912	0.16674	0.0072614	0.802	0.592
grip strength	forelimb grip strength by trial, trial1	4.9053	3.3725	0.83997	0.473	0.152
grip strength	forelimb grip strength by trial, trial2	-1.5350	4.1860	0.049397	0.896	0.715
grip strength	forelimb grip strength by trial, trial3	-4.7084	4.2860	-0.27048	0.596	0.277
heart weight	heart weight, normalized to body weight	0.28613	0.29051	0.53919	0.552	0.334
heart weight	heart weight, weight	0.60934	6.2753	-0.29121	0.958	0.923
hematology	basophil differential (percent of total WBC)	0.015672	0.030416	0.27096	0.875	0.610
hematology	calculated hemoglobin (cHGB)	0.060317	0.18157	-0.10449	0.878	0.742
hematology	eosinophil differential (percent of total WBC)	-0.27332	0.21286	-0.65615	0.602	0.210
hematology	hematocrit (HCT)	0.072228	0.61772	-0.30250	0.958	0.908
hematology	hemoglobin concentration distribution width (HDW)	0.024826	0.023766	0.67340	0.606	0.305
hematology	large unstained cells (percent of total WBC)	-0.022541	0.081500	-0.13153	0.908	0.784
hematology	lymphocyte differential (percent of total WBC)	0.81958	0.47927	0.30823	0.324	0.0983
hematology	mean corpuscular hemoglobin (CHr)	-0.13897	0.055235	-1.1075	0.0858	0.0177
hematology	mean platelet volume (MPV)	0.16636	0.21245	0.82300	0.665	0.440
hematology	mean RBC corpuscular hemoglobin (MCH)	-0.14602	0.056037	-0.56624	0.161	0.0143
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	0.055473	0.18026	0.15125	0.921	0.760
hematology	mean RBC corpuscular volume (MCV)	-0.48632	0.26944	-0.87081	0.227	0.0815
hematology	measured hemoglobin (mHGB)	0.036428	0.18808	-0.14616	0.934	0.848
hematology	monocyte differential (percent of total WBC)	-0.048259	0.12792	0.060174	0.895	0.709
hematology	neutrophil differential (percent of total WBC)	-0.39397	0.40726	-0.18835	0.578	0.342
hematology	platelet count (PLT; units per volume x 10³)	74.769	67.215	1.0158	0.643	0.275
hematology	RBC corpuscular distribution width (RDW)	-0.12292	0.12169	-0.42872	0.579	0.321
hematology	RBC corpuscular hemoglobin concentration mean (CHCM)	0.13010	0.20325	0.32597	0.753	0.527
hematology	red blood cell count (RBC; per volume x 10⁶)	0.11894	0.13497	0.18578	0.647	0.385
hematology	reticulocyte count (Retic; units per volume x 10⁹)	-11.979	11.148	-0.43123	0.679	0.291
hematology	reticulocyte differential (percent of total RBC)	-0.13777	0.10684	-0.39541	0.578	0.207
hematology	white blood cell count (WBC; units per volume x 10³)	0.067038	0.95037	0.23588	0.973	0.944
holeboard	number of hole pokes by individual hole number, 20 min test, 1	-0.42500	0.67276	-0.35235	0.841	0.530
holeboard	number of hole pokes by individual hole number, 20 min test, 2	-0.35000	0.37749	-0.44001	0.807	0.358
holeboard	number of hole pokes by individual hole number, 20 min test, 3	-0.61361	0.34582	-0.95536	0.602	0.0821
holeboard	number of hole pokes by individual hole number, 20 min test, 4	-0.070584	0.56403	0.019413	0.975	0.901
holeboard	number of hole pokes by individual hole number, 20 min test, 5	0.029862	0.60471	0.16362	0.985	0.961
holeboard	number of hole pokes by individual hole number, 20 min test, 6	-0.49828	0.23743	-1.4000	0.554	0.0410
holeboard	number of hole pokes by individual hole number, 20 min test, 7	-0.027280	0.27173	-0.095644	0.998	0.920
holeboard	number of hole pokes by individual hole number, 20 min test, 8	-0.65000	0.40572	-0.95536	0.651	0.115
holeboard	number of hole pokes by individual hole number, 20 min test, 9	-0.20000	0.31409	-0.29297	0.895	0.527
holeboard	number of hole pokes by individual hole number, 20 min test, 10	-0.28750	0.26827	-0.74522	0.834	0.289
holeboard	number of hole pokes by individual hole number, 20 min test, 11	0.15664	0.28427	0.42456	0.910	0.584
holeboard	number of hole pokes by individual hole number, 20 min test, 12	-0.31728	0.46842	-0.45180	0.865	0.501
holeboard	number of hole pokes by individual hole number, 20 min test, 13	0.073126	0.63355	0.15923	0.982	0.909
holeboard	number of hole pokes by individual hole number, 20 min test, 14	-0.38928	0.39753	-0.55327	0.742	0.332
holeboard	number of hole pokes by individual hole number, 20 min test, 15	-0.77500	0.54067	-1.1495	0.634	0.158
holeboard	number of hole pokes by individual hole number, 20 min test, 16	0.51250	0.93513	0.48949	0.885	0.586
holeboard	total number of hole pokes, 20 min test	-3.7044	3.5823	-0.42580	0.594	0.306
light / dark	fecal boli count, 20 min test	-0.59515	0.62073	-0.62687	0.738	0.344
light / dark	latency to enter dark zone, 20 min test	-7.1225	33.012	-0.24721	0.965	0.830
light / dark	number of transitions between light and dark zones, 20 min test	-9.7127	6.4750	-0.88640	0.438	0.140
light / dark	percentage of total time in dark zone, 20 min test	5.8290	2.8930	1.2235	0.341	0.0494
light / dark	percentage of total time in light zone, 20 min test	-5.8290	2.8930	-1.2264	0.338	0.0494
light / dark	time mobile in dark zone, 20 min test	17.309	8.2452	0.85870	0.210	0.0409
light / dark	time mobile in light zone, 20 min test	-13.314	9.7727	-1.1899	0.431	0.179
light / dark	time spent in dark zone, 20 min test	73.032	40.259	1.3239	0.434	0.0758
light / dark	time spent in light zone, 20 min test	-73.032	40.259	-1.3239	0.434	0.0758
open field	average speed in center of arena, 20 min test	0.43749	0.35145	0.68082	0.561	0.219
open field	average speed in periphery of arena, 20 min test	0.33137	0.15249	0.73781	0.131	0.0346
open field	distance traveled habituation ratio, 20 min test	-9.5185	7.6002	-0.78993	0.538	0.216
open field	distance traveled in center of arena, 20 min test	89.802	98.492	0.23233	0.621	0.366
open field	distance traveled in periphery of arena, 20 min test	411.39	157.84	1.1032	0.0793	0.0120
open field	distance traveled slope, 20 min test	-9.9207	7.2171	-0.87539	0.497	0.175
open field	distance traveled, 20 min test, 1st 5min	166.58	69.775	0.93610	0.108	0.0208
open field	distance traveled, 20 min test, 2nd 5min	134.39	59.415	0.97423	0.135	0.0282
open field	distance traveled, 20 min test, 3rd 5min	96.734	57.018	0.61620	0.282	0.0961
open field	distance traveled, 20 min test, 4th 5min	81.908	51.404	0.44600	0.316	0.117
open field	number of clockwise revolution episodes, 20 min test	1.6942	1.4893	0.56775	0.619	0.261
open field	number of counter-clockwise revolution episodes, 20 min test	1.3862	1.3939	0.30894	0.608	0.325
open field	number of fecal boli, 20 min test	0.93495	0.98850	0.94908	0.659	0.351
open field	number of rears in 5 min bins, 20 min test, 1st 5min	2.4586	1.7110	0.46488	0.407	0.157
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	3.7500	2.4460	0.63088	0.393	0.132
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	1.7625	2.8081	0.11369	0.755	0.533
open field	number of rears in 5 min bins, 20 min test, 4th 5min	3.2875	2.6121	0.39031	0.484	0.214
open field	percentage of total time in center of arena, 20 min test	-3.4613	4.0093	-1.0836	0.696	0.392
open field	percentage of total time in center of arena, slope, 20 min test	1.2967	1.5682	0.85200	0.820	0.412
open field	percentage of total time in center, habituation ratio, 20 min test	1.4991	1.6260	0.92574	0.803	0.361
open field	percentage of total time in corners of arena, 20 min test	-0.71613	3.8299	0.17612	0.946	0.852
open field	percentage of total time in corners, habituation ratio, 20 min test	0.65946	1.6862	0.027527	0.945	0.697
open field	percentage of total time in corners, slope, 20 min test	1.0952	1.6727	0.22544	0.889	0.516
open field	permanence time in center of arena, 20 min test	-41.532	48.109	-1.0836	0.696	0.392
open field	permanence time in corners of arena, 20 min test	-8.5976	45.958	0.17612	0.946	0.852
open field	permanence time in periphery of arena, 20 min test	41.556	48.114	1.0812	0.696	0.392
open field	total distance traveled, 20 min test	472.30	199.79	0.81963	0.0956	0.0221
open field	total number of rears, 20 min test	11.150	8.0494	0.41507	0.407	0.172
open field	whole arena average speed, 20 min test	0.39238	0.16653	0.81588	0.0969	0.0225
open field	whole arena resting time, 20 min test	-55.101	19.135	-0.91345	0.0370	0.00589
open field	whole arena time spent mobile, 20 min test	55.143	19.121	1.1206	0.0384	0.00582
open field	whole arena time spent vertical, 20 min test	13.483	7.3558	0.94866	0.311	0.0728
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	2.4737	0.83240	1.2114	0.0809	0.00454
startle / PPI	average baseline movement during background noise	-1.7041	1.2523	-1.1253	0.720	0.181
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	0.079227	0.11660	0.63157	0.779	0.500
startle / PPI	average of each corrected percent pre-pulse inhibition value	0.082386	0.14802	0.73887	0.833	0.581
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.72441	8.5614	-0.027326	0.995	0.933
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	3.7615	8.7438	0.30815	0.883	0.669
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	4.8808	6.9866	0.42356	0.758	0.488
startle / PPI	average startle response to full pulse (120 dB)	7.8251	38.925	0.40068	0.941	0.842
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.20140	40.994	0.18388	0.997	0.996
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.33255	35.702	0.17961	0.997	0.993
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	6.6153	30.947	0.37050	0.912	0.832
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	0.016813	1.0979	0.098941	0.998	0.988
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	0.051727	1.4050	0.070816	0.996	0.971
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	1.5661	1.9284	0.54168	0.791	0.421
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.031883	0.13108	0.34957	0.970	0.809
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.14117	0.19513	1.0783	0.750	0.473
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.11071	0.15091	0.67801	0.714	0.467
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	9.4800	39.245	0.43586	0.923	0.810
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	0.38638	41.002	0.18103	0.997	0.993
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	0.17394	35.977	0.18245	0.996	0.996
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	4.7404	31.655	0.32140	0.939	0.882
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.0075390	0.11479	0.10035	0.994	0.948
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.12342	0.15430	0.88559	0.728	0.428
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.13710	0.13075	0.80735	0.569	0.300
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	56.273	135.47	0.52071	0.851	0.680
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	1.5935	140.16	0.18816	0.997	0.991
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	13.996	125.06	0.24699	0.948	0.911
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	26.190	114.08	0.36001	0.897	0.819
startle / PPI	maximum baseline movement during background noise	-4.1494	3.0691	-1.1332	0.687	0.183
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.28184	9.3543	0.070816	1.00	0.976
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	5.1472	10.055	0.38555	0.837	0.611
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	7.5998	7.8112	0.58271	0.627	0.336
startle / PPI	maximum startle response to full pulse (120 dB)	52.360	134.60	0.49996	0.865	0.699
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.33962	140.02	0.18245	0.999	0.998
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	12.508	124.53	0.24265	0.955	0.920
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	30.470	112.29	0.38706	0.884	0.787
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	-0.90625	2.7418	-0.18530	0.950	0.743
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	-1.7518	3.4228	-0.46376	0.914	0.611
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	3.6115	4.6100	0.47315	0.789	0.438

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

In this plot, data points are the computed genotype effect % vs. C57BL/6NJ controls, for all measured categorical phenotypes in JaxKOMP-EAP

Dimensions Width: × Height: px

Plot Options Group by Procedure

Include Sexes Data Both Females Males

Significance Threshold p-Value Threshold

Download Plot

Procedure	JaxKOMP-EAP Trait	Sex	Trait Effect	P-value

eye morphology	anterior chamber depth	females	1.0 %	1.0
eye morphology	anterior chamber depth	males	0.0 %	1.0
eye morphology	anterior chamber depth	both	1.0 %	1.0
eye morphology	bulging eye	females	1.0 %	1.0
eye morphology	bulging eye	males	0.0 %	1.0
eye morphology	bulging eye	both	1.0 %	1.00
eye morphology	cornea	females	4.0 %	1.0
eye morphology	cornea	males	12.0 %	0.119
eye morphology	cornea	both	6.0 %	0.248
eye morphology	cornea opacity	females	5.0 %	1.00
eye morphology	cornea opacity	males	12.0 %	0.111
eye morphology	cornea opacity	both	4.0 %	0.428
eye morphology	cornea vascularization	females	3.0 %	1.0
eye morphology	cornea vascularization	males	1.0 %	1.0
eye morphology	cornea vascularization	both	2.0 %	1.00
eye morphology	corneal deposits	females	2.0 %	1.0
eye morphology	corneal deposits	males	1.0 %	1.0
eye morphology	corneal deposits	both	1.0 %	1.00
eye morphology	corneal mineralization	females	2.0 %	1.0
eye morphology	corneal mineralization	males	1.0 %	1.0
eye morphology	corneal mineralization	both	1.0 %	1.00
eye morphology	corneal scleralization	females	3.0 %	1.00
eye morphology	corneal scleralization	males	1.0 %	1.0
eye morphology	corneal scleralization	both	2.0 %	1.00
eye morphology	corneal ulcer	females	1.0 %	1.0
eye morphology	corneal ulcer	males	1.0 %	1.0
eye morphology	corneal ulcer	both	1.0 %	1.00
eye morphology	eye closure	females	1.0 %	1.00
eye morphology	eye closure	males	0.0 %	1.0
eye morphology	eye closure	both	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	females	2.0 %	1.00
eye morphology	eye hemorrhage or blood presence	males	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	both	1.0 %	1.00
eye morphology	eyelid morphology	females	1.0 %	1.0
eye morphology	eyelid morphology	males	0.0 %	1.0
eye morphology	eyelid morphology	both	1.0 %	1.0
eye morphology	eyes (present, absent)	females	1.0 %	1.0
eye morphology	eyes (present, absent)	males	0.0 %	1.0
eye morphology	eyes (present, absent)	both	0.0 %	1.0
eye morphology	fusion between cornea and lens	females	4.0 %	1.00
eye morphology	fusion between cornea and lens	males	2.0 %	1.0
eye morphology	fusion between cornea and lens	both	3.0 %	1.00
eye morphology	iris pigmentation	females	2.0 %	1.0
eye morphology	iris pigmentation	males	1.0 %	1.0
eye morphology	iris pigmentation	both	2.0 %	1.00
eye morphology	iris transillumination	females	2.0 %	1.00
eye morphology	iris transillumination	males	1.0 %	1.0
eye morphology	iris transillumination	both	1.0 %	1.00
eye morphology	irispupil	females	4.0 %	1.00
eye morphology	irispupil	males	3.0 %	1.0
eye morphology	irispupil	both	3.0 %	1.00
eye morphology	lacrimation	females	3.0 %	1.0
eye morphology	lacrimation	males	2.0 %	1.0
eye morphology	lacrimation	both	3.0 %	1.0
eye morphology	lens	females	10.0 %	1.00
eye morphology	lens	males	8.0 %	1.0
eye morphology	lens	both	9.0 %	1.0
eye morphology	lens opacity	females	11.0 %	0.316
eye morphology	lens opacity	males	10.0 %	0.368
eye morphology	lens opacity	both	5.0 %	0.287
eye morphology	narrow eye opening	females	2.0 %	1.0
eye morphology	narrow eye opening	males	1.0 %	1.0
eye morphology	narrow eye opening	both	1.0 %	1.0
eye morphology	optic disc	females	4.0 %	1.00
eye morphology	optic disc	males	2.0 %	1.0
eye morphology	optic disc	both	3.0 %	1.00
eye morphology	persistence of hyaloid vascular system	females	6.0 %	0.690
eye morphology	persistence of hyaloid vascular system	males	5.0 %	1.0
eye morphology	persistence of hyaloid vascular system	both	3.0 %	0.790
eye morphology	pupil dilation	females	2.0 %	1.0
eye morphology	pupil dilation	males	1.0 %	1.0
eye morphology	pupil dilation	both	2.0 %	1.0
eye morphology	pupil light response	females	2.0 %	1.00
eye morphology	pupil light response	males	1.0 %	1.0
eye morphology	pupil light response	both	2.0 %	1.00
eye morphology	pupil position	females	4.0 %	1.00
eye morphology	pupil position	males	3.0 %	1.0
eye morphology	pupil position	both	4.0 %	1.00
eye morphology	pupil shape	females	3.0 %	1.00
eye morphology	pupil shape	males	2.0 %	1.0
eye morphology	pupil shape	both	3.0 %	1.00
eye morphology	retina	females	10.0 %	1.0
eye morphology	retina	males	22.0 %	0.129
eye morphology	retina	both	9.0 %	0.407
eye morphology	retinal blood vessels	females	4.0 %	1.0
eye morphology	retinal blood vessels	males	2.0 %	1.0
eye morphology	retinal blood vessels	both	3.0 %	1.0
eye morphology	retinal blood vessels pattern	females	5.0 %	1.0
eye morphology	retinal blood vessels pattern	males	2.0 %	1.0
eye morphology	retinal blood vessels pattern	both	4.0 %	1.00
eye morphology	retinal blood vessels structure	females	4.0 %	1.00
eye morphology	retinal blood vessels structure	males	2.0 %	1.0
eye morphology	retinal blood vessels structure	both	3.0 %	1.00
eye morphology	retinal pigmentation	females	12.0 %	1.0
eye morphology	retinal pigmentation	males	14.0 %	1.0
eye morphology	retinal pigmentation	both	13.0 %	1.0
eye morphology	retinal structure	females	4.0 %	1.00
eye morphology	retinal structure	males	2.0 %	1.0
eye morphology	retinal structure	both	3.0 %	1.00
eye morphology	synechia	females	4.0 %	1.0
eye morphology	synechia	males	2.0 %	1.0
eye morphology	synechia	both	3.0 %	1.00
eye morphology	vitreous	females	4.0 %	1.00
eye morphology	vitreous	males	2.0 %	1.0
eye morphology	vitreous	both	3.0 %	1.00
SHIRPA	activity body position	females	1.0 %	1.0
SHIRPA	activity body position	males	2.0 %	1.0
SHIRPA	activity body position	both	1.0 %	1.00
SHIRPA	aggression	females	0.0 %	1.00
SHIRPA	aggression	males	1.0 %	1.0
SHIRPA	aggression	both	1.0 %	1.0
SHIRPA	body length	females	0.0 %	1.0
SHIRPA	body length	males	0.0 %	1.00
SHIRPA	body length	both	0.0 %	1.00
SHIRPA	body position	females	0.0 %	1.0
SHIRPA	body position	males	1.0 %	1.0
SHIRPA	body position	both	0.0 %	1.0
SHIRPA	body thickness	females	1.0 %	1.0
SHIRPA	body thickness	males	0.0 %	1.0
SHIRPA	body thickness	both	0.0 %	1.0
SHIRPA	coat color abdomen	females	3.0 %	1.00
SHIRPA	coat color abdomen	males	4.0 %	1.0
SHIRPA	coat color abdomen	both	4.0 %	1.0
SHIRPA	coat color back	females	0.0 %	1.0
SHIRPA	coat color back	males	0.0 %	1.00
SHIRPA	coat color back	both	0.0 %	1.00
SHIRPA	coat color head	females	0.0 %	1.0
SHIRPA	coat color head	males	0.0 %	1.00
SHIRPA	coat color head	both	0.0 %	1.0
SHIRPA	coat color pattern abdomen	females	1.0 %	1.0
SHIRPA	coat color pattern abdomen	males	1.0 %	1.0
SHIRPA	coat color pattern abdomen	both	1.0 %	1.0
SHIRPA	coat color pattern back	females	0.0 %	1.0
SHIRPA	coat color pattern back	males	0.0 %	1.00
SHIRPA	coat color pattern back	both	0.0 %	1.0
SHIRPA	coat color pattern head	females	0.0 %	1.0
SHIRPA	coat color pattern head	males	0.0 %	1.0
SHIRPA	coat color pattern head	both	0.0 %	1.00
SHIRPA	coat hair abdomen texture appearance	females	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	males	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	both	2.0 %	1.0
SHIRPA	coat hair back texture appearance	females	0.0 %	1.0
SHIRPA	coat hair back texture appearance	males	0.0 %	1.0
SHIRPA	coat hair back texture appearance	both	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	females	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	males	1.0 %	1.00
SHIRPA	coat hair distribution abdomen	both	1.0 %	1.00
SHIRPA	coat hair distribution back	females	0.0 %	1.0
SHIRPA	coat hair distribution back	males	0.0 %	1.0
SHIRPA	coat hair distribution back	both	0.0 %	1.0
SHIRPA	coat hair distribution head	females	1.0 %	1.00
SHIRPA	coat hair distribution head	males	1.0 %	1.0
SHIRPA	coat hair distribution head	both	1.0 %	1.0
SHIRPA	coat hair head texture appearance	females	0.0 %	1.00
SHIRPA	coat hair head texture appearance	males	0.0 %	1.0
SHIRPA	coat hair head texture appearance	both	0.0 %	1.0
SHIRPA	contact righting	females	5.0 %	1.0
SHIRPA	contact righting	males	5.0 %	1.00
SHIRPA	contact righting	both	5.0 %	1.00
SHIRPA	ear morphology	females	0.0 %	1.0
SHIRPA	ear morphology	males	0.0 %	1.0
SHIRPA	ear morphology	both	0.0 %	1.0
SHIRPA	fat distribution	females	0.0 %	1.0
SHIRPA	fat distribution	males	0.0 %	1.0
SHIRPA	fat distribution	both	0.0 %	1.00
SHIRPA	forelimb digit number	females	0.0 %	1.00
SHIRPA	forelimb digit number	males	0.0 %	1.0
SHIRPA	forelimb digit number	both	0.0 %	1.00
SHIRPA	forelimb digit position	females	0.0 %	1.0
SHIRPA	forelimb digit position	males	0.0 %	1.0
SHIRPA	forelimb digit position	both	0.0 %	1.0
SHIRPA	forelimb digit shape	females	0.0 %	1.0
SHIRPA	forelimb digit shape	males	0.0 %	1.0
SHIRPA	forelimb digit shape	both	0.0 %	1.0
SHIRPA	forelimb digit size	females	0.0 %	1.0
SHIRPA	forelimb digit size	males	0.0 %	1.0
SHIRPA	forelimb digit size	both	0.0 %	1.0
SHIRPA	forelimb footpads	females	0.0 %	1.0
SHIRPA	forelimb footpads	males	0.0 %	1.0
SHIRPA	forelimb footpads	both	0.0 %	1.0
SHIRPA	forelimb nail length	females	0.0 %	1.0
SHIRPA	forelimb nail length	males	0.0 %	1.0
SHIRPA	forelimb nail length	both	0.0 %	1.0
SHIRPA	forelimb nail number	females	0.0 %	1.0
SHIRPA	forelimb nail number	males	0.0 %	1.0
SHIRPA	forelimb nail number	both	0.0 %	1.0
SHIRPA	forelimb nail position	females	0.0 %	1.0
SHIRPA	forelimb nail position	males	0.0 %	1.0
SHIRPA	forelimb nail position	both	0.0 %	1.0
SHIRPA	forelimb nail shape	females	0.0 %	1.0
SHIRPA	forelimb nail shape	males	0.0 %	1.0
SHIRPA	forelimb nail shape	both	0.0 %	1.0
SHIRPA	forelimbs position	females	0.0 %	1.0
SHIRPA	forelimbs position	males	0.0 %	1.0
SHIRPA	forelimbs position	both	0.0 %	1.0
SHIRPA	forelimbs shape	females	0.0 %	1.0
SHIRPA	forelimbs shape	males	0.0 %	1.0
SHIRPA	forelimbs shape	both	0.0 %	1.0
SHIRPA	forelimbs size	females	0.0 %	1.0
SHIRPA	forelimbs size	males	0.0 %	1.0
SHIRPA	forelimbs size	both	0.0 %	1.0
SHIRPA	forepaw position	females	0.0 %	1.0
SHIRPA	forepaw position	males	0.0 %	1.0
SHIRPA	forepaw position	both	0.0 %	1.0
SHIRPA	forepaw shape	females	0.0 %	1.0
SHIRPA	forepaw shape	males	0.0 %	1.0
SHIRPA	forepaw shape	both	0.0 %	1.0
SHIRPA	forepaw size	females	0.0 %	1.0
SHIRPA	forepaw size	males	0.0 %	1.0
SHIRPA	forepaw size	both	0.0 %	1.0
SHIRPA	gait (fluidity)	females	0.0 %	1.0
SHIRPA	gait (fluidity)	males	0.0 %	1.00
SHIRPA	gait (fluidity)	both	0.0 %	1.00
SHIRPA	genitalia morphology	females	0.0 %	1.00
SHIRPA	genitalia morphology	males	0.0 %	1.0
SHIRPA	genitalia morphology	both	0.0 %	1.00
SHIRPA	genitalia presence	females	0.0 %	1.0
SHIRPA	genitalia presence	males	0.0 %	1.0
SHIRPA	genitalia presence	both	0.0 %	1.0
SHIRPA	genitalia size	females	0.0 %	1.0
SHIRPA	genitalia size	males	0.0 %	1.0
SHIRPA	genitalia size	both	0.0 %	1.0
SHIRPA	head bobbing	females	0.0 %	1.0
SHIRPA	head bobbing	males	0.0 %	1.0
SHIRPA	head bobbing	both	0.0 %	1.0
SHIRPA	head morphology	females	0.0 %	1.0
SHIRPA	head morphology	males	0.0 %	1.00
SHIRPA	head morphology	both	0.0 %	1.0
SHIRPA	head size	females	0.0 %	1.0
SHIRPA	head size	males	0.0 %	1.0
SHIRPA	head size	both	0.0 %	1.00
SHIRPA	hindlimb digit number	females	1.0 %	1.00
SHIRPA	hindlimb digit number	males	0.0 %	1.0
SHIRPA	hindlimb digit number	both	0.0 %	1.00
SHIRPA	hindlimb digit position	females	0.0 %	1.0
SHIRPA	hindlimb digit position	males	0.0 %	1.0
SHIRPA	hindlimb digit position	both	0.0 %	1.0
SHIRPA	hindlimb digit shape	females	0.0 %	1.0
SHIRPA	hindlimb digit shape	males	0.0 %	1.0
SHIRPA	hindlimb digit shape	both	0.0 %	1.0
SHIRPA	hindlimb digit size	females	0.0 %	1.00
SHIRPA	hindlimb digit size	males	0.0 %	1.0
SHIRPA	hindlimb digit size	both	0.0 %	1.00
SHIRPA	hindlimb nail length	females	0.0 %	1.0
SHIRPA	hindlimb nail length	males	0.0 %	1.0
SHIRPA	hindlimb nail length	both	0.0 %	1.00
SHIRPA	hindlimb nail number	females	0.0 %	1.0
SHIRPA	hindlimb nail number	males	1.0 %	1.0
SHIRPA	hindlimb nail number	both	0.0 %	1.00
SHIRPA	hindlimb nail position	females	0.0 %	1.0
SHIRPA	hindlimb nail position	males	0.0 %	1.0
SHIRPA	hindlimb nail position	both	0.0 %	1.0
SHIRPA	hindlimb nail shape	females	0.0 %	1.0
SHIRPA	hindlimb nail shape	males	0.0 %	1.0
SHIRPA	hindlimb nail shape	both	0.0 %	1.0
SHIRPA	hindlimbs footpads	females	0.0 %	1.0
SHIRPA	hindlimbs footpads	males	0.0 %	1.0
SHIRPA	hindlimbs footpads	both	0.0 %	1.0
SHIRPA	hindlimbs position	females	0.0 %	1.0
SHIRPA	hindlimbs position	males	0.0 %	1.0
SHIRPA	hindlimbs position	both	0.0 %	1.0
SHIRPA	hindlimbs shape	females	0.0 %	1.0
SHIRPA	hindlimbs shape	males	0.0 %	1.0
SHIRPA	hindlimbs shape	both	0.0 %	1.0
SHIRPA	hindlimbs size	females	0.0 %	1.0
SHIRPA	hindlimbs size	males	0.0 %	1.0
SHIRPA	hindlimbs size	both	0.0 %	1.0
SHIRPA	hindpaw position	females	0.0 %	1.0
SHIRPA	hindpaw position	males	0.0 %	1.0
SHIRPA	hindpaw position	both	0.0 %	1.0
SHIRPA	hindpaw shape	females	0.0 %	1.0
SHIRPA	hindpaw shape	males	0.0 %	1.0
SHIRPA	hindpaw shape	both	0.0 %	1.0
SHIRPA	hindpaw size	females	0.0 %	1.0
SHIRPA	hindpaw size	males	0.0 %	1.0
SHIRPA	hindpaw size	both	0.0 %	1.0
SHIRPA	limb grasp	females	9.0 %	1.00
SHIRPA	limb grasp	males	6.0 %	1.0
SHIRPA	limb grasp	both	7.0 %	0.624
SHIRPA	lower lip morphology	females	0.0 %	1.0
SHIRPA	lower lip morphology	males	0.0 %	1.0
SHIRPA	lower lip morphology	both	0.0 %	1.0
SHIRPA	lower teeth appearance	females	0.0 %	1.0
SHIRPA	lower teeth appearance	males	0.0 %	1.00
SHIRPA	lower teeth appearance	both	0.0 %	1.00
SHIRPA	mouth morphology	females	0.0 %	1.0
SHIRPA	mouth morphology	males	0.0 %	1.00
SHIRPA	mouth morphology	both	0.0 %	1.00
SHIRPA	salivation	females	0.0 %	1.0
SHIRPA	salivation	males	0.0 %	1.0
SHIRPA	salivation	both	0.0 %	1.0
SHIRPA	skin color back paws	females	0.0 %	1.0
SHIRPA	skin color back paws	males	0.0 %	1.0
SHIRPA	skin color back paws	both	0.0 %	1.0
SHIRPA	skin color ear	females	0.0 %	1.0
SHIRPA	skin color ear	males	0.0 %	1.0
SHIRPA	skin color ear	both	0.0 %	1.0
SHIRPA	skin color front paws	females	0.0 %	1.0
SHIRPA	skin color front paws	males	0.0 %	1.0
SHIRPA	skin color front paws	both	0.0 %	1.0
SHIRPA	skin color snout	females	0.0 %	1.0
SHIRPA	skin color snout	males	0.0 %	1.0
SHIRPA	skin color snout	both	0.0 %	1.0
SHIRPA	skin color tail	females	0.0 %	1.0
SHIRPA	skin color tail	males	0.0 %	1.0
SHIRPA	skin color tail	both	0.0 %	1.0
SHIRPA	skin color whole body	females	0.0 %	1.0
SHIRPA	skin color whole body	males	0.0 %	1.0
SHIRPA	skin color whole body	both	0.0 %	1.0
SHIRPA	skin texture back paw	females	0.0 %	1.0
SHIRPA	skin texture back paw	males	0.0 %	1.0
SHIRPA	skin texture back paw	both	0.0 %	1.0
SHIRPA	skin texture ear	females	0.0 %	1.0
SHIRPA	skin texture ear	males	0.0 %	1.0
SHIRPA	skin texture ear	both	0.0 %	1.0
SHIRPA	skin texture front paws	females	0.0 %	1.0
SHIRPA	skin texture front paws	males	0.0 %	1.0
SHIRPA	skin texture front paws	both	0.0 %	1.0
SHIRPA	skin texture snout	females	0.0 %	1.0
SHIRPA	skin texture snout	males	0.0 %	1.0
SHIRPA	skin texture snout	both	0.0 %	1.0
SHIRPA	skin texture tail	females	0.0 %	1.0
SHIRPA	skin texture tail	males	0.0 %	1.0
SHIRPA	skin texture tail	both	0.0 %	1.0
SHIRPA	skin texture whole body	females	0.0 %	1.0
SHIRPA	skin texture whole body	males	0.0 %	1.00
SHIRPA	skin texture whole body	both	0.0 %	1.00
SHIRPA	snout size	females	0.0 %	1.0
SHIRPA	snout size	males	1.0 %	1.0
SHIRPA	snout size	both	0.0 %	1.0
SHIRPA	startle response	females	0.0 %	1.00
SHIRPA	startle response	males	0.0 %	1.00
SHIRPA	startle response	both	0.0 %	1.00
SHIRPA	tail curvature	females	0.0 %	1.00
SHIRPA	tail curvature	males	0.0 %	1.0
SHIRPA	tail curvature	both	0.0 %	1.0
SHIRPA	tail elevation	females	1.0 %	1.00
SHIRPA	tail elevation	males	2.0 %	1.0
SHIRPA	tail elevation	both	1.0 %	1.0
SHIRPA	tail length	females	0.0 %	1.0
SHIRPA	tail length	males	0.0 %	1.0
SHIRPA	tail length	both	0.0 %	1.00
SHIRPA	tail morphology	females	0.0 %	1.00
SHIRPA	tail morphology	males	0.0 %	1.0
SHIRPA	tail morphology	both	0.0 %	1.00
SHIRPA	tail presence	females	0.0 %	1.0
SHIRPA	tail presence	males	0.0 %	1.0
SHIRPA	tail presence	both	0.0 %	1.0
SHIRPA	tail shape	females	0.0 %	1.0
SHIRPA	tail shape	males	0.0 %	1.0
SHIRPA	tail shape	both	0.0 %	1.00
SHIRPA	tail thickness	females	0.0 %	1.0
SHIRPA	tail thickness	males	0.0 %	1.0
SHIRPA	tail thickness	both	0.0 %	1.0
SHIRPA	teeth presence	females	0.0 %	1.0
SHIRPA	teeth presence	males	0.0 %	1.00
SHIRPA	teeth presence	both	0.0 %	1.00
SHIRPA	transfer arousal	females	1.0 %	1.0
SHIRPA	transfer arousal	males	2.0 %	1.00
SHIRPA	transfer arousal	both	1.0 %	1.0
SHIRPA	tremor	females	0.0 %	1.0
SHIRPA	tremor	males	0.0 %	1.0
SHIRPA	tremor	both	0.0 %	1.00
SHIRPA	trunk curl	females	0.0 %	1.00
SHIRPA	trunk curl	males	0.0 %	1.0
SHIRPA	trunk curl	both	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	females	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	males	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	both	0.0 %	1.00
SHIRPA	upper lip morphology	females	0.0 %	1.0
SHIRPA	upper lip morphology	males	0.0 %	1.0
SHIRPA	upper lip morphology	both	0.0 %	1.0
SHIRPA	upper teeth appearance	females	0.0 %	1.0
SHIRPA	upper teeth appearance	males	0.0 %	1.0
SHIRPA	upper teeth appearance	both	0.0 %	1.00
SHIRPA	vibrissae appearance	females	2.0 %	1.0
SHIRPA	vibrissae appearance	males	1.0 %	1.0
SHIRPA	vibrissae appearance	both	1.0 %	1.0
SHIRPA	vibrissae presence	females	2.0 %	1.00
SHIRPA	vibrissae presence	males	1.0 %	1.0
SHIRPA	vibrissae presence	both	2.0 %	1.0
SHIRPA	vocalization	females	98.0 %	3.38e-9
SHIRPA	vocalization	males	98.0 %	0.00000802
SHIRPA	vocalization	both	98.0 %	2.58e-14

GENOTYPE CORRELATION PLOT

Correlate Ccdc170^em1(IMPC)J/Mmjax -/- with genotype: