MPD: JaxKOMP-EAP genotype: Brms1l<sup>em1(IMPC)J</sup>/Mmjax -/+

JaxKOMP-EAP effect sizes: Brms1l^em1(IMPC)J/Mmjax -/+ Gene Brms1l

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	-1.9084	2.6779	-0.80722	0.823	0.484
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	-4.6019	3.1140	-0.95356	0.642	0.154
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	-4.4111	3.1168	-1.0831	0.530	0.172
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	1.3810	5.5128	0.10363	0.930	0.805
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	-6.4444	4.2093	-0.96742	0.518	0.140
body composition	body length	-0.14486	0.050416	-1.2926	0.106	0.0140
body composition	body weight (at time of DXA)	-1.7303	1.4050	-1.0808	0.457	0.240
body composition	bone area, whole body scan, head excluded	-0.83703	0.23942	-2.3338	0.0455	0.00394
body composition	bone mineral content of whole body scan, head excluded	-0.071090	0.019897	-2.4818	0.0431	0.00340
body composition	bone mineral content to body weight ratio	-0.0020580	0.00067402	-2.0288	0.0789	0.0100
body composition	bone mineral density of whole body scan, head excluded	-0.0019064	0.00083518	-1.7223	0.207	0.0415
body composition	fat tissue mass of whole body scan, head excluded	1.2699	0.43071	1.6707	0.0971	0.0122
body composition	fat tissue mass to body weight ratio	0.042485	0.014846	1.6544	0.0861	0.0143
body composition	lean tissue mass of whole body scan, head excluded	-0.90520	0.44496	-1.7472	0.290	0.0646
body composition	lean tissue mass to body weight ratio	-0.031483	0.013242	-1.5552	0.171	0.0349
body composition	percent fat, whole body scan, head excluded	4.1468	1.4642	1.7472	0.0947	0.0151
body composition	ratio of soft-tissue attenuation coefficients	-0.0045796	0.0016124	-1.7337	0.0937	0.0149
body composition	tissue area	0.064785	0.30891	0.41926	0.948	0.837
body composition	total tissue mass, whole body scan, head excluded	0.47216	0.20009	0.78128	0.163	0.0361
clinical blood chemistry	alanine transaminase (plasma ALT)	7.1497	4.1844	0.55175	0.455	0.103
clinical blood chemistry	albumin (plasma Alb)	0.20290	0.52047	0.33255	0.887	0.701
clinical blood chemistry	alkaline phosphatase (plasma ALP)	2.7912	3.3946	-0.050324	0.663	0.421
clinical blood chemistry	aspartate transaminase (plasma AST)	11.885	6.6984	0.51531	0.383	0.0920
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	0.016364	0.095905	0.073875	0.963	0.866
clinical blood chemistry	blood urea nitrogen (BUN)	0.29670	1.4422	0.078188	0.928	0.839
clinical blood chemistry	calcium (plasma Ca)	0.18289	0.077756	1.5213	0.142	0.0296
clinical blood chemistry	creatinine (plasma)	0.034809	0.051633	0.93688	0.726	0.508
clinical blood chemistry	glucose (plasma GLU, no fast)	-13.120	15.024	-0.22542	0.602	0.393
clinical blood chemistry	HDL cholesterol (plasma HDL)	-1.1670	2.6435	-0.61560	0.869	0.664
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	0.0038758	0.0064185	0.081938	0.813	0.553
clinical blood chemistry	phosphorus (plasma phosphate)	-1.0239	0.44687	-1.4935	0.180	0.0329
clinical blood chemistry	total bilirubin (plasma TBIL)	0.00060585	0.0060797	0.055384	0.979	0.922
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	-2.7402	3.6254	-0.71935	0.748	0.459
clinical blood chemistry	total protein (plasma TP)	0.085216	0.67518	0.0057099	0.956	0.901
clinical blood chemistry	triglyceride (plasma TG, no fast)	7.3625	11.751	0.61807	0.772	0.538
glucose tolerance test	amount glucose injected	-0.14187	1.9283	0.35447	0.977	0.942
glucose tolerance test	plasma glucose, 0min	3.0751	5.0308	0.089347	0.738	0.546
glucose tolerance test	plasma glucose, 15min	40.774	20.459	1.2060	0.278	0.0558
glucose tolerance test	plasma glucose, 30min	14.196	22.212	0.53673	0.785	0.528
glucose tolerance test	plasma glucose, 60min	-20.737	13.086	-0.76983	0.413	0.124
glucose tolerance test	plasma glucose, 120min	9.0552	9.5327	0.48356	0.641	0.350
grip strength	body weight (at time of grip strength test)	-0.33054	0.39292	-0.10609	0.600	0.405
grip strength	forelimb and hindlimb grip strength (mean of trials), average	15.540	7.2565	1.3492	0.133	0.0384
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	0.74288	0.36969	1.2543	0.173	0.0514
grip strength	forelimb and hindlimb grip strength by trial, trial1	22.145	9.8298	1.6031	0.172	0.0298
grip strength	forelimb and hindlimb grip strength by trial, trial2	5.5474	8.2756	0.58505	0.734	0.506
grip strength	forelimb and hindlimb grip strength by trial, trial3	17.644	8.2499	1.2969	0.188	0.0386
grip strength	forelimb grip strength (mean of trials), average	12.503	4.1929	1.8150	0.0491	0.00486
grip strength	forelimb grip strength (mean of trials), average normalized to bw	0.71796	0.22579	1.8705	0.0395	0.00289
grip strength	forelimb grip strength by trial, trial1	8.4625	6.9061	1.2323	0.586	0.228
grip strength	forelimb grip strength by trial, trial2	13.663	6.1739	1.6522	0.219	0.0327
grip strength	forelimb grip strength by trial, trial3	14.201	5.4933	1.6579	0.134	0.0135
heart weight	heart weight, normalized to body weight	-0.046091	0.087538	-0.64551	0.774	0.607
heart weight	heart weight, weight	-1.7594	2.5365	-0.59473	0.691	0.499
hematology	basophil differential (percent of total WBC)	-0.078048	0.046909	-1.0745	0.534	0.113
hematology	calculated hemoglobin (cHGB)	0.25405	0.16287	0.51564	0.391	0.134
hematology	eosinophil differential (percent of total WBC)	-0.47225	0.30060	-1.2083	0.526	0.133
hematology	hematocrit (HCT)	0.35030	0.44368	0.0013668	0.691	0.440
hematology	hemoglobin concentration distribution width (HDW)	0.015604	0.019951	0.41868	0.719	0.443
hematology	large unstained cells (percent of total WBC)	-0.039601	0.057952	-0.26089	0.791	0.502
hematology	lymphocyte differential (percent of total WBC)	0.093382	0.54500	-0.0054670	0.940	0.866
hematology	mean corpuscular hemoglobin (CHr)	-0.036710	0.058726	-0.28806	0.749	0.539
hematology	mean platelet volume (MPV)	-0.22532	0.10585	-1.3321	0.160	0.0459
hematology	mean RBC corpuscular hemoglobin (MCH)	-0.10270	0.069105	-0.40727	0.497	0.153
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	0.16979	0.20315	0.40234	0.746	0.413
hematology	mean RBC corpuscular volume (MCV)	-0.58702	0.27220	-1.0181	0.159	0.0434
hematology	measured hemoglobin (mHGB)	0.26216	0.14828	0.45638	0.350	0.0923
hematology	monocyte differential (percent of total WBC)	0.15459	0.080584	0.71715	0.367	0.0702
hematology	neutrophil differential (percent of total WBC)	0.77909	0.38242	0.42524	0.224	0.0558
hematology	platelet count (PLT; units per volume x 10³)	-10.727	24.200	-0.091701	0.871	0.663
hematology	RBC corpuscular distribution width (RDW)	-0.18378	0.10531	-0.67837	0.316	0.0963
hematology	RBC corpuscular hemoglobin concentration mean (CHCM)	0.38133	0.21505	0.94270	0.281	0.0914
hematology	red blood cell count (RBC; per volume x 10⁶)	0.24838	0.10486	0.72875	0.171	0.0280
hematology	reticulocyte count (Retic; units per volume x 10⁹)	-22.229	13.875	-0.87135	0.498	0.125
hematology	reticulocyte differential (percent of total RBC)	-0.27067	0.12822	-0.93026	0.337	0.0476
hematology	white blood cell count (WBC; units per volume x 10³)	1.1614	0.86590	0.94085	0.397	0.195
holeboard	number of hole pokes by individual hole number, 20 min test, 1	-1.4250	0.77415	-1.3603	0.494	0.0716
holeboard	number of hole pokes by individual hole number, 20 min test, 2	-0.076669	0.43349	0.021101	0.980	0.860
holeboard	number of hole pokes by individual hole number, 20 min test, 3	-0.63750	0.40135	-0.99335	0.661	0.119
holeboard	number of hole pokes by individual hole number, 20 min test, 4	-0.46685	0.63813	-0.39762	0.832	0.468
holeboard	number of hole pokes by individual hole number, 20 min test, 5	-0.41654	0.53323	-0.58845	0.846	0.438
holeboard	number of hole pokes by individual hole number, 20 min test, 6	-0.11199	0.26202	-0.30315	0.946	0.671
holeboard	number of hole pokes by individual hole number, 20 min test, 7	-0.28750	0.26283	-0.78883	0.835	0.279
holeboard	number of hole pokes by individual hole number, 20 min test, 8	-0.87584	0.61832	-1.3393	0.703	0.163
holeboard	number of hole pokes by individual hole number, 20 min test, 9	0.058511	0.41116	0.21619	0.986	0.887
holeboard	number of hole pokes by individual hole number, 20 min test, 10	-0.23750	0.25582	-0.57078	0.861	0.358
holeboard	number of hole pokes by individual hole number, 20 min test, 11	0.15000	0.38766	0.41349	0.936	0.700
holeboard	number of hole pokes by individual hole number, 20 min test, 12	-0.96250	0.75609	-1.4091	0.651	0.209
holeboard	number of hole pokes by individual hole number, 20 min test, 13	-0.59063	0.64776	-0.49520	0.750	0.366
holeboard	number of hole pokes by individual hole number, 20 min test, 14	-0.70925	0.58654	-1.0566	0.680	0.232
holeboard	number of hole pokes by individual hole number, 20 min test, 15	0.28750	0.44811	0.50476	0.860	0.524
holeboard	number of hole pokes by individual hole number, 20 min test, 16	0.11385	0.76934	0.12345	0.961	0.883
holeboard	total number of hole pokes, 20 min test	-6.6623	4.0007	-0.86150	0.353	0.102
light / dark	fecal boli count, 20 min test	0.50000	0.47185	0.60237	0.701	0.294
light / dark	latency to enter dark zone, 20 min test	49.807	28.928	0.76834	0.523	0.0913
light / dark	number of transitions between light and dark zones, 20 min test	-10.937	7.8815	-1.0115	0.488	0.171
light / dark	percentage of total time in dark zone, 20 min test	1.0910	2.8787	0.33898	0.897	0.706
light / dark	percentage of total time in light zone, 20 min test	-1.0910	2.8787	-0.34471	0.898	0.706
light / dark	time mobile in dark zone, 20 min test	-22.566	8.7076	-1.3337	0.105	0.0126
light / dark	time mobile in light zone, 20 min test	-2.9037	12.068	-0.45009	0.910	0.811
light / dark	time spent in dark zone, 20 min test	-17.044	44.237	-0.051399	0.908	0.702
light / dark	time spent in light zone, 20 min test	17.044	44.237	0.051399	0.908	0.702
open field	average speed in center of arena, 20 min test	-0.29991	0.28087	-0.63744	0.636	0.291
open field	average speed in periphery of arena, 20 min test	0.026625	0.12030	-0.42239	0.909	0.826
open field	distance traveled habituation ratio, 20 min test	-20.106	6.2099	-1.6162	0.0442	0.00214
open field	distance traveled in center of arena, 20 min test	183.99	88.700	0.78810	0.177	0.0432
open field	distance traveled in periphery of arena, 20 min test	-163.92	125.57	-1.0909	0.425	0.198
open field	distance traveled slope, 20 min test	-20.131	5.9782	-1.7012	0.0326	0.00147
open field	distance traveled, 20 min test, 1st 5min	143.45	59.009	0.76631	0.101	0.0187
open field	distance traveled, 20 min test, 2nd 5min	-13.506	40.467	-0.66734	0.868	0.740
open field	distance traveled, 20 min test, 3rd 5min	-75.637	43.873	-1.2776	0.274	0.0909
open field	distance traveled, 20 min test, 4th 5min	-35.300	46.672	-0.85780	0.687	0.453
open field	number of clockwise revolution episodes, 20 min test	-0.20000	0.96033	-0.52872	0.947	0.836
open field	number of counter-clockwise revolution episodes, 20 min test	2.1125	1.2316	0.67744	0.338	0.0925
open field	number of fecal boli, 20 min test	-0.020478	0.78007	0.25842	0.995	0.979
open field	number of rears in 5 min bins, 20 min test, 1st 5min	1.2561	2.2665	0.13609	0.792	0.582
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	0.036676	2.5426	-0.34720	0.996	0.989
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	-2.3286	2.6132	-0.82528	0.646	0.377
open field	number of rears in 5 min bins, 20 min test, 4th 5min	-0.53750	2.6933	-0.45641	0.921	0.843
open field	percentage of total time in center of arena, 20 min test	10.088	3.0035	1.8578	0.0419	0.00150
open field	percentage of total time in center of arena, slope, 20 min test	0.14179	1.5830	0.19387	0.978	0.929
open field	percentage of total time in center, habituation ratio, 20 min test	-0.21259	1.6349	0.011412	0.973	0.897
open field	percentage of total time in corners of arena, 20 min test	-12.165	3.4355	-1.8284	0.0296	0.000874
open field	percentage of total time in corners, habituation ratio, 20 min test	1.7093	1.7647	0.48793	0.805	0.337
open field	percentage of total time in corners, slope, 20 min test	1.0901	1.7426	0.21993	0.895	0.534
open field	permanence time in center of arena, 20 min test	121.09	36.041	1.8578	0.0418	0.00150
open field	permanence time in corners of arena, 20 min test	-145.96	41.225	-1.8284	0.0297	0.000875
open field	permanence time in periphery of arena, 20 min test	-121.11	36.038	-1.8578	0.0417	0.00150
open field	total distance traveled, 20 min test	22.705	153.35	-0.43269	0.938	0.883
open field	total number of rears, 20 min test	-1.4079	8.6363	-0.43860	0.944	0.871
open field	whole arena average speed, 20 min test	0.019375	0.12783	-0.43122	0.937	0.880
open field	whole arena resting time, 20 min test	-7.6937	14.902	0.34435	0.765	0.608
open field	whole arena time spent mobile, 20 min test	7.7050	14.899	-0.19387	0.766	0.607
open field	whole arena time spent vertical, 20 min test	-3.7340	7.6601	-0.42975	0.847	0.628
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	-0.15554	1.0932	0.11742	0.972	0.888
startle / PPI	average baseline movement during background noise	0.42993	1.4269	0.37350	0.958	0.764
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	-0.0091933	0.063149	-0.17107	0.951	0.885
startle / PPI	average of each corrected percent pre-pulse inhibition value	-0.0063108	0.060308	-0.13012	0.963	0.917
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	5.2766	6.1540	0.62304	0.879	0.395
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-2.3619	7.1409	-0.30082	0.915	0.742
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-3.4284	5.8342	-0.45442	0.815	0.559
startle / PPI	average startle response to full pulse (120 dB)	-11.488	34.987	-0.049761	0.895	0.744
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-20.526	34.955	-0.23257	0.756	0.560
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.12649	32.376	0.16823	0.998	0.997
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-4.6553	24.948	0.063795	0.923	0.853
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	-0.17708	1.5112	-0.053970	0.982	0.907
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	-0.53437	1.3749	-0.35553	0.948	0.699
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	0.48027	1.6415	0.059583	0.943	0.771
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.048190	0.069578	0.49837	0.903	0.492
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.023266	0.077426	-0.30263	0.927	0.765
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-0.019773	0.066758	-0.34754	0.899	0.768
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	-11.281	35.292	-0.039943	0.894	0.751
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	-20.195	35.394	-0.21676	0.763	0.571
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	0.89281	32.653	0.19958	0.990	0.978
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	-4.3396	25.099	0.090496	0.929	0.863
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.057711	0.073950	0.52553	0.897	0.439
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.046681	0.082260	-0.43227	0.801	0.573
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-0.011641	0.067371	-0.29293	0.951	0.864
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	-70.235	131.16	-0.20387	0.802	0.595
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	-91.877	124.80	-0.33471	0.679	0.465
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	10.080	115.50	0.22969	0.956	0.931
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	-5.1891	93.283	0.17107	0.974	0.956
startle / PPI	maximum baseline movement during background noise	-0.28750	3.6803	0.046955	0.985	0.938
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	5.5662	6.7209	0.58936	0.895	0.412
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-5.1382	7.7498	-0.52392	0.785	0.510
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-2.9614	6.0921	-0.41133	0.829	0.629
startle / PPI	maximum startle response to full pulse (120 dB)	-70.523	130.33	-0.20387	0.800	0.591
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-91.922	123.90	-0.34065	0.674	0.462
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	8.4235	114.88	0.21389	0.966	0.942
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-6.2424	93.336	0.15261	0.970	0.947
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	-0.10625	3.4761	0.079247	0.997	0.976
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	-1.2625	2.8872	-0.33175	0.931	0.664
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	0.52282	3.8262	-0.058180	0.976	0.892

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Sex	Trait Effect	P-value
eye morphology	anterior chamber depth	females	62.0 %	1.17e-8
eye morphology	anterior chamber depth	males	37.0 %	0.0000107
eye morphology	anterior chamber depth	both	49.0 %	1.15e-12
eye morphology	bulging eye	females	62.0 %	9.09e-9
eye morphology	bulging eye	males	37.0 %	0.00000795
eye morphology	bulging eye	both	49.0 %	2.24e-13
eye morphology	cornea	females	62.0 %	8.91e-8
eye morphology	cornea	males	48.0 %	0.00000184
eye morphology	cornea	both	54.0 %	5.81e-13
eye morphology	cornea opacity	females	62.0 %	1.46e-7
eye morphology	cornea opacity	males	37.0 %	0.0000395
eye morphology	cornea opacity	both	49.0 %	1.58e-11
eye morphology	cornea vascularization	females	62.0 %	6.01e-8
eye morphology	cornea vascularization	males	37.0 %	0.0000264
eye morphology	cornea vascularization	both	49.0 %	8.05e-12
eye morphology	corneal deposits	females	62.0 %	8.18e-8
eye morphology	corneal deposits	males	37.0 %	0.0000432
eye morphology	corneal deposits	both	49.0 %	6.38e-12
eye morphology	corneal mineralization	females	62.0 %	7.44e-8
eye morphology	corneal mineralization	males	37.0 %	0.0000274
eye morphology	corneal mineralization	both	49.0 %	9.20e-12
eye morphology	corneal scleralization	females	62.0 %	1.21e-7
eye morphology	corneal scleralization	males	37.0 %	0.0000460
eye morphology	corneal scleralization	both	49.0 %	1.18e-11
eye morphology	corneal ulcer	females	62.0 %	5.12e-8
eye morphology	corneal ulcer	males	37.0 %	0.0000169
eye morphology	corneal ulcer	both	49.0 %	5.98e-12
eye morphology	eye closure	females	62.0 %	8.97e-9
eye morphology	eye closure	males	37.0 %	0.00000787
eye morphology	eye closure	both	49.0 %	3.48e-13
eye morphology	eye hemorrhage or blood presence	females	62.0 %	6.95e-8
eye morphology	eye hemorrhage or blood presence	males	37.0 %	0.0000196
eye morphology	eye hemorrhage or blood presence	both	49.0 %	4.89e-12
eye morphology	eyelid morphology	females	62.0 %	1.77e-8
eye morphology	eyelid morphology	males	37.0 %	0.00000787
eye morphology	eyelid morphology	both	49.0 %	7.72e-13
eye morphology	eyes (present, absent)	females	1.0 %	1.0
eye morphology	eyes (present, absent)	males	0.0 %	1.0
eye morphology	eyes (present, absent)	both	0.0 %	1.0
eye morphology	fusion between cornea and lens	females	61.0 %	0.00000272
eye morphology	fusion between cornea and lens	males	36.0 %	0.000468
eye morphology	fusion between cornea and lens	both	48.0 %	3.96e-9
eye morphology	iris pigmentation	females	62.0 %	7.50e-8
eye morphology	iris pigmentation	males	37.0 %	0.0000420
eye morphology	iris pigmentation	both	49.0 %	1.13e-11
eye morphology	iris transillumination	females	62.0 %	2.34e-8
eye morphology	iris transillumination	males	37.0 %	0.0000228
eye morphology	iris transillumination	both	49.0 %	1.06e-12
eye morphology	irispupil	females	62.0 %	1.69e-7
eye morphology	irispupil	males	37.0 %	0.0000680
eye morphology	irispupil	both	49.0 %	1.88e-11
eye morphology	lacrimation	females	61.0 %	4.78e-7
eye morphology	lacrimation	males	37.0 %	0.000370
eye morphology	lacrimation	both	49.0 %	3.32e-10
eye morphology	lens	females	61.0 %	0.00000410
eye morphology	lens	males	37.0 %	0.00128
eye morphology	lens	both	49.0 %	5.99e-9
eye morphology	lens opacity	females	61.0 %	0.0000139
eye morphology	lens opacity	males	36.0 %	0.00270
eye morphology	lens opacity	both	48.0 %	5.03e-8
eye morphology	narrow eye opening	females	62.0 %	6.33e-8
eye morphology	narrow eye opening	males	37.0 %	0.0000167
eye morphology	narrow eye opening	both	49.0 %	4.45e-12
eye morphology	optic disc	females	61.0 %	0.00000532
eye morphology	optic disc	males	36.0 %	0.00171
eye morphology	optic disc	both	48.0 %	2.02e-8
eye morphology	persistence of hyaloid vascular system	females	61.0 %	0.0000318
eye morphology	persistence of hyaloid vascular system	males	36.0 %	0.00295
eye morphology	persistence of hyaloid vascular system	both	48.0 %	1.58e-7
eye morphology	pupil dilation	females	62.0 %	4.67e-8
eye morphology	pupil dilation	males	37.0 %	0.0000747
eye morphology	pupil dilation	both	49.0 %	8.98e-12
eye morphology	pupil light response	females	62.0 %	7.48e-8
eye morphology	pupil light response	males	37.0 %	0.0000557
eye morphology	pupil light response	both	49.0 %	7.02e-12
eye morphology	pupil position	females	62.0 %	2.64e-7
eye morphology	pupil position	males	37.0 %	0.0000727
eye morphology	pupil position	both	49.0 %	3.17e-11
eye morphology	pupil shape	females	62.0 %	1.55e-7
eye morphology	pupil shape	males	37.0 %	0.0000595
eye morphology	pupil shape	both	49.0 %	1.77e-11
eye morphology	retina	females	61.0 %	0.0000226
eye morphology	retina	males	59.0 %	0.0000794
eye morphology	retina	both	56.0 %	2.50e-9
eye morphology	retinal blood vessels	females	61.0 %	0.00000174
eye morphology	retinal blood vessels	males	36.0 %	0.000679
eye morphology	retinal blood vessels	both	48.0 %	6.91e-9
eye morphology	retinal blood vessels pattern	females	61.0 %	0.00000727
eye morphology	retinal blood vessels pattern	males	36.0 %	0.00175
eye morphology	retinal blood vessels pattern	both	48.0 %	2.72e-8
eye morphology	retinal blood vessels structure	females	61.0 %	0.00000481
eye morphology	retinal blood vessels structure	males	36.0 %	0.00107
eye morphology	retinal blood vessels structure	both	48.0 %	1.42e-8
eye morphology	retinal pigmentation	females	61.0 %	0.0000228
eye morphology	retinal pigmentation	males	36.0 %	0.00432
eye morphology	retinal pigmentation	both	48.0 %	1.05e-7
eye morphology	retinal structure	females	61.0 %	0.00000522
eye morphology	retinal structure	males	36.0 %	0.00130
eye morphology	retinal structure	both	48.0 %	1.83e-8
eye morphology	synechia	females	61.0 %	0.00000109
eye morphology	synechia	males	36.0 %	0.000635
eye morphology	synechia	both	48.0 %	2.50e-9
eye morphology	vitreous	females	61.0 %	0.00000199
eye morphology	vitreous	males	36.0 %	0.000531
eye morphology	vitreous	both	48.0 %	3.44e-9
SHIRPA	activity body position	females	12.0 %	0.0797
SHIRPA	activity body position	males	2.0 %	1.0
SHIRPA	activity body position	both	6.0 %	0.193
SHIRPA	aggression	females	0.0 %	1.00
SHIRPA	aggression	males	37.0 %	0.0000190
SHIRPA	aggression	both	18.0 %	0.000109
SHIRPA	body length	females	0.0 %	1.0
SHIRPA	body length	males	0.0 %	1.00
SHIRPA	body length	both	0.0 %	1.00
SHIRPA	body position	females	0.0 %	1.0
SHIRPA	body position	males	1.0 %	1.0
SHIRPA	body position	both	0.0 %	1.0
SHIRPA	body thickness	females	1.0 %	1.0
SHIRPA	body thickness	males	0.0 %	1.0
SHIRPA	body thickness	both	0.0 %	1.0
SHIRPA	coat color abdomen	females	3.0 %	1.00
SHIRPA	coat color abdomen	males	4.0 %	1.0
SHIRPA	coat color abdomen	both	4.0 %	1.0
SHIRPA	coat color back	females	0.0 %	1.0
SHIRPA	coat color back	males	0.0 %	1.00
SHIRPA	coat color back	both	0.0 %	1.00
SHIRPA	coat color head	females	0.0 %	1.0
SHIRPA	coat color head	males	0.0 %	1.00
SHIRPA	coat color head	both	0.0 %	1.0
SHIRPA	coat color pattern abdomen	females	1.0 %	1.0
SHIRPA	coat color pattern abdomen	males	1.0 %	1.0
SHIRPA	coat color pattern abdomen	both	1.0 %	1.0
SHIRPA	coat color pattern back	females	0.0 %	1.0
SHIRPA	coat color pattern back	males	0.0 %	1.00
SHIRPA	coat color pattern back	both	0.0 %	1.0
SHIRPA	coat color pattern head	females	0.0 %	1.0
SHIRPA	coat color pattern head	males	0.0 %	1.0
SHIRPA	coat color pattern head	both	0.0 %	1.00
SHIRPA	coat hair abdomen texture appearance	females	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	males	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	both	2.0 %	1.0
SHIRPA	coat hair back texture appearance	females	0.0 %	1.0
SHIRPA	coat hair back texture appearance	males	0.0 %	1.0
SHIRPA	coat hair back texture appearance	both	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	females	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	males	1.0 %	1.00
SHIRPA	coat hair distribution abdomen	both	1.0 %	1.00
SHIRPA	coat hair distribution back	females	0.0 %	1.0
SHIRPA	coat hair distribution back	males	0.0 %	1.0
SHIRPA	coat hair distribution back	both	0.0 %	1.0
SHIRPA	coat hair distribution head	females	1.0 %	1.00
SHIRPA	coat hair distribution head	males	1.0 %	1.0
SHIRPA	coat hair distribution head	both	1.0 %	1.0
SHIRPA	coat hair head texture appearance	females	0.0 %	1.00
SHIRPA	coat hair head texture appearance	males	0.0 %	1.0
SHIRPA	coat hair head texture appearance	both	0.0 %	1.0
SHIRPA	contact righting	females	5.0 %	1.0
SHIRPA	contact righting	males	5.0 %	1.00
SHIRPA	contact righting	both	5.0 %	1.00
SHIRPA	ear morphology	females	0.0 %	1.0
SHIRPA	ear morphology	males	0.0 %	1.0
SHIRPA	ear morphology	both	0.0 %	1.0
SHIRPA	fat distribution	females	0.0 %	1.0
SHIRPA	fat distribution	males	0.0 %	1.0
SHIRPA	fat distribution	both	0.0 %	1.00
SHIRPA	forelimb digit number	females	0.0 %	1.00
SHIRPA	forelimb digit number	males	0.0 %	1.0
SHIRPA	forelimb digit number	both	0.0 %	1.00
SHIRPA	forelimb digit position	females	0.0 %	1.0
SHIRPA	forelimb digit position	males	0.0 %	1.0
SHIRPA	forelimb digit position	both	0.0 %	1.0
SHIRPA	forelimb digit shape	females	0.0 %	1.0
SHIRPA	forelimb digit shape	males	0.0 %	1.0
SHIRPA	forelimb digit shape	both	0.0 %	1.0
SHIRPA	forelimb digit size	females	0.0 %	1.0
SHIRPA	forelimb digit size	males	0.0 %	1.0
SHIRPA	forelimb digit size	both	0.0 %	1.0
SHIRPA	forelimb footpads	females	0.0 %	1.0
SHIRPA	forelimb footpads	males	0.0 %	1.0
SHIRPA	forelimb footpads	both	0.0 %	1.0
SHIRPA	forelimb nail length	females	0.0 %	1.0
SHIRPA	forelimb nail length	males	0.0 %	1.0
SHIRPA	forelimb nail length	both	0.0 %	1.0
SHIRPA	forelimb nail number	females	0.0 %	1.0
SHIRPA	forelimb nail number	males	0.0 %	1.0
SHIRPA	forelimb nail number	both	0.0 %	1.0
SHIRPA	forelimb nail position	females	0.0 %	1.0
SHIRPA	forelimb nail position	males	0.0 %	1.0
SHIRPA	forelimb nail position	both	0.0 %	1.0
SHIRPA	forelimb nail shape	females	0.0 %	1.0
SHIRPA	forelimb nail shape	males	0.0 %	1.0
SHIRPA	forelimb nail shape	both	0.0 %	1.0
SHIRPA	forelimbs position	females	0.0 %	1.0
SHIRPA	forelimbs position	males	0.0 %	1.0
SHIRPA	forelimbs position	both	0.0 %	1.0
SHIRPA	forelimbs shape	females	0.0 %	1.0
SHIRPA	forelimbs shape	males	0.0 %	1.0
SHIRPA	forelimbs shape	both	0.0 %	1.0
SHIRPA	forelimbs size	females	0.0 %	1.0
SHIRPA	forelimbs size	males	0.0 %	1.0
SHIRPA	forelimbs size	both	0.0 %	1.0
SHIRPA	forepaw position	females	0.0 %	1.0
SHIRPA	forepaw position	males	0.0 %	1.0
SHIRPA	forepaw position	both	0.0 %	1.0
SHIRPA	forepaw shape	females	0.0 %	1.0
SHIRPA	forepaw shape	males	0.0 %	1.0
SHIRPA	forepaw shape	both	0.0 %	1.0
SHIRPA	forepaw size	females	0.0 %	1.0
SHIRPA	forepaw size	males	0.0 %	1.0
SHIRPA	forepaw size	both	0.0 %	1.0
SHIRPA	gait (fluidity)	females	0.0 %	1.0
SHIRPA	gait (fluidity)	males	0.0 %	1.00
SHIRPA	gait (fluidity)	both	0.0 %	1.00
SHIRPA	genitalia morphology	females	0.0 %	1.00
SHIRPA	genitalia morphology	males	0.0 %	1.0
SHIRPA	genitalia morphology	both	0.0 %	1.00
SHIRPA	genitalia presence	females	0.0 %	1.0
SHIRPA	genitalia presence	males	0.0 %	1.0
SHIRPA	genitalia presence	both	0.0 %	1.0
SHIRPA	genitalia size	females	0.0 %	1.0
SHIRPA	genitalia size	males	0.0 %	1.0
SHIRPA	genitalia size	both	0.0 %	1.0
SHIRPA	head bobbing	females	0.0 %	1.0
SHIRPA	head bobbing	males	0.0 %	1.0
SHIRPA	head bobbing	both	0.0 %	1.0
SHIRPA	head morphology	females	0.0 %	1.0
SHIRPA	head morphology	males	0.0 %	1.00
SHIRPA	head morphology	both	0.0 %	1.0
SHIRPA	head size	females	0.0 %	1.0
SHIRPA	head size	males	0.0 %	1.0
SHIRPA	head size	both	0.0 %	1.00
SHIRPA	hindlimb digit number	females	1.0 %	1.00
SHIRPA	hindlimb digit number	males	0.0 %	1.0
SHIRPA	hindlimb digit number	both	0.0 %	1.00
SHIRPA	hindlimb digit position	females	0.0 %	1.0
SHIRPA	hindlimb digit position	males	0.0 %	1.0
SHIRPA	hindlimb digit position	both	0.0 %	1.0
SHIRPA	hindlimb digit shape	females	0.0 %	1.0
SHIRPA	hindlimb digit shape	males	0.0 %	1.0
SHIRPA	hindlimb digit shape	both	0.0 %	1.0
SHIRPA	hindlimb digit size	females	0.0 %	1.00
SHIRPA	hindlimb digit size	males	0.0 %	1.0
SHIRPA	hindlimb digit size	both	0.0 %	1.00
SHIRPA	hindlimb nail length	females	0.0 %	1.0
SHIRPA	hindlimb nail length	males	12.0 %	0.00642
SHIRPA	hindlimb nail length	both	6.0 %	0.00651
SHIRPA	hindlimb nail number	females	0.0 %	1.0
SHIRPA	hindlimb nail number	males	1.0 %	1.0
SHIRPA	hindlimb nail number	both	0.0 %	1.00
SHIRPA	hindlimb nail position	females	0.0 %	1.0
SHIRPA	hindlimb nail position	males	0.0 %	1.0
SHIRPA	hindlimb nail position	both	0.0 %	1.0
SHIRPA	hindlimb nail shape	females	0.0 %	1.0
SHIRPA	hindlimb nail shape	males	0.0 %	1.0
SHIRPA	hindlimb nail shape	both	0.0 %	1.0
SHIRPA	hindlimbs footpads	females	0.0 %	1.0
SHIRPA	hindlimbs footpads	males	0.0 %	1.0
SHIRPA	hindlimbs footpads	both	0.0 %	1.0
SHIRPA	hindlimbs position	females	0.0 %	1.0
SHIRPA	hindlimbs position	males	0.0 %	1.0
SHIRPA	hindlimbs position	both	0.0 %	1.0
SHIRPA	hindlimbs shape	females	0.0 %	1.0
SHIRPA	hindlimbs shape	males	0.0 %	1.0
SHIRPA	hindlimbs shape	both	0.0 %	1.0
SHIRPA	hindlimbs size	females	0.0 %	1.0
SHIRPA	hindlimbs size	males	0.0 %	1.0
SHIRPA	hindlimbs size	both	0.0 %	1.0
SHIRPA	hindpaw position	females	0.0 %	1.0
SHIRPA	hindpaw position	males	0.0 %	1.0
SHIRPA	hindpaw position	both	0.0 %	1.0
SHIRPA	hindpaw shape	females	0.0 %	1.0
SHIRPA	hindpaw shape	males	0.0 %	1.0
SHIRPA	hindpaw shape	both	0.0 %	1.0
SHIRPA	hindpaw size	females	0.0 %	1.0
SHIRPA	hindpaw size	males	0.0 %	1.0
SHIRPA	hindpaw size	both	0.0 %	1.0
SHIRPA	limb grasp	females	4.0 %	0.524
SHIRPA	limb grasp	males	19.0 %	0.0730
SHIRPA	limb grasp	both	11.0 %	0.106
SHIRPA	lower lip morphology	females	0.0 %	1.0
SHIRPA	lower lip morphology	males	0.0 %	1.0
SHIRPA	lower lip morphology	both	0.0 %	1.0
SHIRPA	lower teeth appearance	females	0.0 %	1.0
SHIRPA	lower teeth appearance	males	0.0 %	1.00
SHIRPA	lower teeth appearance	both	0.0 %	1.00
SHIRPA	mouth morphology	females	0.0 %	1.0
SHIRPA	mouth morphology	males	0.0 %	1.00
SHIRPA	mouth morphology	both	0.0 %	1.00
SHIRPA	salivation	females	0.0 %	1.0
SHIRPA	salivation	males	0.0 %	1.0
SHIRPA	salivation	both	0.0 %	1.0
SHIRPA	skin color back paws	females	0.0 %	1.0
SHIRPA	skin color back paws	males	0.0 %	1.0
SHIRPA	skin color back paws	both	0.0 %	1.0
SHIRPA	skin color ear	females	0.0 %	1.0
SHIRPA	skin color ear	males	0.0 %	1.0
SHIRPA	skin color ear	both	0.0 %	1.0
SHIRPA	skin color front paws	females	0.0 %	1.0
SHIRPA	skin color front paws	males	0.0 %	1.0
SHIRPA	skin color front paws	both	0.0 %	1.0
SHIRPA	skin color snout	females	0.0 %	1.0
SHIRPA	skin color snout	males	0.0 %	1.0
SHIRPA	skin color snout	both	0.0 %	1.0
SHIRPA	skin color tail	females	0.0 %	1.0
SHIRPA	skin color tail	males	0.0 %	1.0
SHIRPA	skin color tail	both	0.0 %	1.0
SHIRPA	skin color whole body	females	0.0 %	1.0
SHIRPA	skin color whole body	males	0.0 %	1.0
SHIRPA	skin color whole body	both	0.0 %	1.0
SHIRPA	skin texture back paw	females	0.0 %	1.0
SHIRPA	skin texture back paw	males	0.0 %	1.0
SHIRPA	skin texture back paw	both	0.0 %	1.0
SHIRPA	skin texture ear	females	0.0 %	1.0
SHIRPA	skin texture ear	males	0.0 %	1.0
SHIRPA	skin texture ear	both	0.0 %	1.0
SHIRPA	skin texture front paws	females	0.0 %	1.0
SHIRPA	skin texture front paws	males	0.0 %	1.0
SHIRPA	skin texture front paws	both	0.0 %	1.0
SHIRPA	skin texture snout	females	0.0 %	1.0
SHIRPA	skin texture snout	males	0.0 %	1.0
SHIRPA	skin texture snout	both	0.0 %	1.0
SHIRPA	skin texture tail	females	0.0 %	1.0
SHIRPA	skin texture tail	males	0.0 %	1.0
SHIRPA	skin texture tail	both	0.0 %	1.0
SHIRPA	skin texture whole body	females	0.0 %	1.0
SHIRPA	skin texture whole body	males	0.0 %	1.00
SHIRPA	skin texture whole body	both	0.0 %	1.00
SHIRPA	snout size	females	0.0 %	1.0
SHIRPA	snout size	males	1.0 %	1.0
SHIRPA	snout size	both	0.0 %	1.0
SHIRPA	startle response	females	0.0 %	1.00
SHIRPA	startle response	males	0.0 %	1.00
SHIRPA	startle response	both	0.0 %	1.00
SHIRPA	tail curvature	females	0.0 %	1.00
SHIRPA	tail curvature	males	0.0 %	1.0
SHIRPA	tail curvature	both	0.0 %	1.0
SHIRPA	tail elevation	females	1.0 %	1.00
SHIRPA	tail elevation	males	2.0 %	1.0
SHIRPA	tail elevation	both	1.0 %	1.0
SHIRPA	tail length	females	0.0 %	1.0
SHIRPA	tail length	males	0.0 %	1.0
SHIRPA	tail length	both	0.0 %	1.00
SHIRPA	tail morphology	females	0.0 %	1.00
SHIRPA	tail morphology	males	0.0 %	1.0
SHIRPA	tail morphology	both	0.0 %	1.00
SHIRPA	tail presence	females	0.0 %	1.0
SHIRPA	tail presence	males	0.0 %	1.0
SHIRPA	tail presence	both	0.0 %	1.0
SHIRPA	tail shape	females	0.0 %	1.0
SHIRPA	tail shape	males	0.0 %	1.0
SHIRPA	tail shape	both	0.0 %	1.00
SHIRPA	tail thickness	females	0.0 %	1.0
SHIRPA	tail thickness	males	0.0 %	1.0
SHIRPA	tail thickness	both	0.0 %	1.0
SHIRPA	teeth presence	females	0.0 %	1.0
SHIRPA	teeth presence	males	0.0 %	1.00
SHIRPA	teeth presence	both	0.0 %	1.00
SHIRPA	transfer arousal	females	1.0 %	1.0
SHIRPA	transfer arousal	males	12.0 %	0.0653
SHIRPA	transfer arousal	both	6.0 %	0.109
SHIRPA	tremor	females	0.0 %	1.0
SHIRPA	tremor	males	0.0 %	1.0
SHIRPA	tremor	both	0.0 %	1.00
SHIRPA	trunk curl	females	0.0 %	1.00
SHIRPA	trunk curl	males	0.0 %	1.0
SHIRPA	trunk curl	both	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	females	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	males	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	both	0.0 %	1.00
SHIRPA	upper lip morphology	females	0.0 %	1.0
SHIRPA	upper lip morphology	males	0.0 %	1.0
SHIRPA	upper lip morphology	both	0.0 %	1.0
SHIRPA	upper teeth appearance	females	0.0 %	1.0
SHIRPA	upper teeth appearance	males	0.0 %	1.0
SHIRPA	upper teeth appearance	both	0.0 %	1.00
SHIRPA	vibrissae appearance	females	2.0 %	1.0
SHIRPA	vibrissae appearance	males	1.0 %	1.0
SHIRPA	vibrissae appearance	both	1.0 %	1.0
SHIRPA	vibrissae presence	females	2.0 %	1.00
SHIRPA	vibrissae presence	males	1.0 %	1.0
SHIRPA	vibrissae presence	both	2.0 %	1.0
SHIRPA	vocalization	females	2.0 %	1.00
SHIRPA	vocalization	males	2.0 %	1.0
SHIRPA	vocalization	both	2.0 %	1.00

GENOTYPE CORRELATION PLOT

Correlate Brms1l^em1(IMPC)J/Mmjax -/+ with genotype: