MPD: JaxKOMP-EAP genotype: Gramd1b<sup>em1(IMPC)J</sup>/Mmjax -/+

JaxKOMP-EAP effect sizes: Gramd1b^em1(IMPC)J/Mmjax -/+ Gene Gramd1b

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	2.7597	1.6720	0.57807	0.531	0.123
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	7.2727	2.4994	1.3556	0.234	0.0122
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	4.3482	2.5702	0.67851	0.466	0.116
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	9.6212	3.3814	1.3522	0.160	0.0138
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	-1.6025	3.8947	-0.28854	0.879	0.687
body composition	body length	-0.026883	0.036738	-0.11632	0.742	0.473
body composition	body weight (at time of DXA)	0.14393	1.1759	0.21241	0.962	0.904
body composition	bone area, whole body scan, head excluded	-0.20799	0.14027	-0.67620	0.415	0.154
body composition	bone mineral content of whole body scan, head excluded	-0.0072095	0.0085275	-0.27512	0.673	0.408
body composition	bone mineral content to body weight ratio	-0.00011700	0.00044235	0.0027305	0.912	0.794
body composition	bone mineral density of whole body scan, head excluded	0.00027463	0.00063401	0.31882	0.841	0.670
body composition	fat tissue mass of whole body scan, head excluded	0.33665	0.46422	0.54932	0.708	0.477
body composition	fat tissue mass to body weight ratio	0.0078974	0.013179	0.41728	0.761	0.556
body composition	lean tissue mass of whole body scan, head excluded	-0.096026	0.44284	-0.35840	0.931	0.831
body composition	lean tissue mass to body weight ratio	-0.0069701	0.013134	-0.43023	0.804	0.602
body composition	percent fat, whole body scan, head excluded	0.80510	1.2784	0.46089	0.741	0.536
body composition	ratio of soft-tissue attenuation coefficients	-0.00088887	0.0014190	-0.46045	0.746	0.539
body composition	tissue area	-0.015217	0.38402	0.13848	0.995	0.969
body composition	total tissue mass, whole body scan, head excluded	0.091433	0.60559	-0.013653	0.945	0.882
clinical blood chemistry	alanine transaminase (plasma ALT)	10.508	5.9545	0.76492	0.437	0.0909
clinical blood chemistry	albumin (plasma Alb)	0.56736	0.48388	0.83271	0.572	0.253
clinical blood chemistry	alkaline phosphatase (plasma ALP)	6.3125	2.2638	0.60196	0.0717	0.0104
clinical blood chemistry	aspartate transaminase (plasma AST)	3.4337	3.9240	0.17672	0.697	0.391
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	-0.15024	0.12380	-0.48219	0.635	0.238
clinical blood chemistry	blood urea nitrogen (BUN)	4.0625	1.6101	1.5309	0.121	0.0190
clinical blood chemistry	calcium (plasma Ca)	0.016434	0.049860	0.46004	0.867	0.745
clinical blood chemistry	creatinine (plasma)	0.038750	0.019765	1.0759	0.228	0.0622
clinical blood chemistry	glucose (plasma GLU, no fast)	-8.4471	9.6316	-0.033571	0.598	0.390
clinical blood chemistry	HDL cholesterol (plasma HDL)	0.49522	3.1025	-0.21200	0.960	0.875
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	-0.0095540	0.0080050	-0.67137	0.582	0.245
clinical blood chemistry	phosphorus (plasma phosphate)	0.56289	0.19165	0.79932	0.0792	0.00740
clinical blood chemistry	total bilirubin (plasma TBIL)	0.013750	0.0085257	0.88111	0.408	0.120
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	1.3877	3.8424	0.012086	0.898	0.721
clinical blood chemistry	total protein (plasma TP)	0.66862	0.56656	0.44539	0.524	0.250
clinical blood chemistry	triglyceride (plasma TG, no fast)	6.4341	9.1671	0.56691	0.737	0.490
EKG	duration of PQ interval	-0.59576	1.0338	-0.50187	0.924	0.569
EKG	duration of PR interval	-0.23845	1.0797	-0.13338	0.959	0.827
EKG	duration of QRS interval	0.67931	0.33380	1.6952	0.885	0.0511
EKG	duration of QT interval	-0.47585	0.85716	-0.28805	0.898	0.583
EKG	duration of QTC interval, calculated by dividing QT interval by square root of preceding RR interval	-0.36543	0.97582	-0.32394	0.956	0.711
EKG	duration of RR interval	0.82576	1.4290	0.69744	0.840	0.568
EKG	duration of ST interval	-1.1304	0.85760	-0.85839	0.700	0.198
EKG	heart rate coefficient of variation (signal intensity)	1.5244	0.89390	1.3067	0.806	0.0988
EKG	heart rate variability, mean of differences between sequential beats; beats per min	11.567	6.3400	1.3657	0.773	0.0784
EKG	heart rate, beats per min	-6.9914	12.530	-0.72014	0.833	0.581
EKG	mean R amplitude, mean amplitude of signal measured from isoelectric line to peak of QRS	-0.22131	0.10030	-1.7209	0.281	0.0354
EKG	mean SR amplitude, mean amplitude of signal measured from signal minimum line to peak of QRS	-0.22024	0.11853	-1.3352	0.363	0.0733
EKG	number of signals	10.305	4.6467	1.5940	0.452	0.0346
EKG	proportion of number pairs of successive beat-to-beat intervals that exceed 50 ms	-0.67192	2.1490	-0.077392	0.970	0.757
EKG	QT dispersion, measured as inter-lead variability of QT intervals	4.1152	3.7338	1.1484	0.881	0.279
EKG	QTc dispersion, calculated as rate-corrected QT dispersion	4.3363	4.0092	1.1103	0.883	0.288
EKG	root mean square of successive differences of neighboring RR intervals	2.7911	1.9500	1.4188	0.843	0.163
glucose tolerance test	amount glucose injected	-1.7459	5.1154	-0.16785	0.915	0.737
glucose tolerance test	plasma glucose, 0min	-3.5522	7.4348	-0.58167	0.804	0.638
glucose tolerance test	plasma glucose, 15min	0.39465	21.020	0.11280	0.992	0.985
glucose tolerance test	plasma glucose, 30min	19.618	18.005	0.70849	0.626	0.290
glucose tolerance test	plasma glucose, 60min	3.7577	10.856	0.29526	0.901	0.733
glucose tolerance test	plasma glucose, 120min	19.468	8.4381	1.1457	0.232	0.0325
heart weight	heart weight, normalized to body weight	0.21877	0.10144	0.31669	0.154	0.0405
heart weight	heart weight, weight	5.7892	2.8758	0.38423	0.197	0.0546
hematology	basophil differential (percent of total WBC)	0.010576	0.056178	0.19618	0.965	0.852
hematology	calculated hemoglobin (cHGB)	-0.13180	0.15031	-0.67996	0.660	0.390
hematology	eosinophil differential (percent of total WBC)	-0.027083	0.25277	0.0034188	0.970	0.916
hematology	hematocrit (HCT)	-0.11010	0.39437	-0.48282	0.892	0.783
hematology	hemoglobin concentration distribution width (HDW)	-0.018278	0.017017	-0.50377	0.596	0.294
hematology	large unstained cells (percent of total WBC)	-0.10580	0.047365	-0.72723	0.260	0.0355
hematology	lymphocyte differential (percent of total WBC)	5.1283	3.5992	1.6380	0.419	0.168
hematology	mean corpuscular hemoglobin (CHr)	0.031213	0.059466	0.29094	0.801	0.605
hematology	mean platelet volume (MPV)	0.10155	0.037594	0.49487	0.0671	0.0130
hematology	mean RBC corpuscular hemoglobin (MCH)	0.072893	0.092263	0.25083	0.764	0.438
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	-0.15746	0.22619	-0.35671	0.797	0.493
hematology	mean RBC corpuscular volume (MCV)	0.40187	0.21406	0.72069	0.216	0.0732
hematology	measured hemoglobin (mHGB)	-0.056250	0.16591	-0.37584	0.878	0.738
hematology	monocyte differential (percent of total WBC)	-0.097533	0.39761	-0.12332	0.930	0.808
hematology	neutrophil differential (percent of total WBC)	-4.6829	3.4445	-1.6486	0.431	0.188
hematology	platelet count (PLT; units per volume x 10³)	-14.495	39.768	-0.14124	0.896	0.719
hematology	RBC corpuscular distribution width (RDW)	-0.084271	0.22201	-0.30551	0.851	0.708
hematology	RBC corpuscular hemoglobin concentration mean (CHCM)	-0.24978	0.16192	-0.69429	0.354	0.137
hematology	red blood cell count (RBC; per volume x 10⁶)	-0.088125	0.10242	-0.70223	0.657	0.398
hematology	reticulocyte count (Retic; units per volume x 10⁹)	4.9083	14.107	0.31774	0.918	0.731
hematology	reticulocyte differential (percent of total RBC)	0.074891	0.14432	0.53732	0.840	0.609
hematology	white blood cell count (WBC; units per volume x 10³)	-1.6130	0.73016	-0.91147	0.136	0.0374
holeboard	number of hole pokes by individual hole number, 20 min test, 1	-0.42370	0.90666	-0.34696	0.893	0.643
holeboard	number of hole pokes by individual hole number, 20 min test, 2	-0.41935	0.37615	-0.54094	0.775	0.272
holeboard	number of hole pokes by individual hole number, 20 min test, 3	-0.88479	0.59399	-1.3952	0.661	0.144
holeboard	number of hole pokes by individual hole number, 20 min test, 4	-1.5760	1.0049	-1.5277	0.600	0.125
holeboard	number of hole pokes by individual hole number, 20 min test, 5	-0.069124	0.47708	-0.0042199	0.970	0.886
holeboard	number of hole pokes by individual hole number, 20 min test, 6	0.19155	0.33409	0.55327	0.930	0.570
holeboard	number of hole pokes by individual hole number, 20 min test, 7	-0.23502	0.34857	-0.66550	0.919	0.504
holeboard	number of hole pokes by individual hole number, 20 min test, 8	-0.33460	0.49052	-0.43258	0.874	0.499
holeboard	number of hole pokes by individual hole number, 20 min test, 9	0.76136	0.51938	1.3145	0.617	0.151
holeboard	number of hole pokes by individual hole number, 20 min test, 10	0.36160	0.23726	0.95134	0.728	0.136
holeboard	number of hole pokes by individual hole number, 20 min test, 11	-0.077618	0.31421	-0.18001	0.970	0.806
holeboard	number of hole pokes by individual hole number, 20 min test, 12	-0.47125	0.42508	-0.71420	0.715	0.275
holeboard	number of hole pokes by individual hole number, 20 min test, 13	-0.40553	0.81443	-0.30845	0.883	0.621
holeboard	number of hole pokes by individual hole number, 20 min test, 14	-0.95853	0.90567	-1.4417	0.718	0.296
holeboard	number of hole pokes by individual hole number, 20 min test, 15	0.62881	0.50485	1.0566	0.671	0.220
holeboard	number of hole pokes by individual hole number, 20 min test, 16	-0.81567	1.1865	-0.68832	0.818	0.496
holeboard	total number of hole pokes, 20 min test	-4.7327	5.6774	-0.58100	0.674	0.410
light / dark	fecal boli count, 20 min test	-0.052054	0.53735	-0.034483	0.966	0.923
light / dark	latency to enter dark zone, 20 min test	-11.033	30.567	-0.31047	0.924	0.720
light / dark	number of transitions between light and dark zones, 20 min test	-6.2676	8.2644	-0.52316	0.727	0.453
light / dark	percentage of total time in dark zone, 20 min test	0.60378	3.0607	0.23607	0.951	0.845
light / dark	percentage of total time in light zone, 20 min test	-0.60378	3.0607	-0.24164	0.952	0.845
light / dark	time mobile in dark zone, 20 min test	20.145	11.865	0.96742	0.343	0.0973
light / dark	time mobile in light zone, 20 min test	15.432	13.181	0.64841	0.512	0.249
light / dark	time spent in dark zone, 20 min test	6.4751	34.576	0.30622	0.958	0.852
light / dark	time spent in light zone, 20 min test	-6.4751	34.576	-0.30622	0.958	0.852
open field	average speed in center of arena, 20 min test	0.085142	0.40786	0.062471	0.947	0.836
open field	average speed in periphery of arena, 20 min test	0.50326	0.15165	1.2449	0.0186	0.00197
open field	distance traveled habituation ratio, 20 min test	-14.144	6.8975	-1.1698	0.266	0.0469
open field	distance traveled in center of arena, 20 min test	67.680	75.286	0.085358	0.628	0.374
open field	distance traveled in periphery of arena, 20 min test	508.84	160.59	1.4028	0.0292	0.00298
open field	distance traveled slope, 20 min test	-11.107	6.6239	-0.96137	0.376	0.101
open field	distance traveled, 20 min test, 1st 5min	228.17	69.260	1.3409	0.0236	0.00207
open field	distance traveled, 20 min test, 2nd 5min	108.80	56.808	0.68252	0.222	0.0626
open field	distance traveled, 20 min test, 3rd 5min	147.71	52.595	1.0983	0.0556	0.00766
open field	distance traveled, 20 min test, 4th 5min	95.724	48.615	0.57136	0.212	0.0559
open field	number of clockwise revolution episodes, 20 min test	2.5945	1.1189	1.0068	0.189	0.0256
open field	number of counter-clockwise revolution episodes, 20 min test	3.6562	1.2463	1.4136	0.0738	0.00552
open field	number of fecal boli, 20 min test	0.072601	0.82778	0.33752	0.979	0.931
open field	number of rears in 5 min bins, 20 min test, 1st 5min	6.8639	1.6055	1.6412	0.00496	0.000115
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	3.7761	2.5404	0.63909	0.419	0.145
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	6.2241	1.8888	1.0764	0.0338	0.00207
open field	number of rears in 5 min bins, 20 min test, 4th 5min	2.7227	2.4772	0.26835	0.556	0.278
open field	percentage of total time in center of arena, 20 min test	-1.4372	2.1857	-0.55719	0.786	0.515
open field	percentage of total time in center of arena, slope, 20 min test	-0.92549	0.97505	-0.39321	0.792	0.348
open field	percentage of total time in center, habituation ratio, 20 min test	-0.39618	1.0597	-0.094795	0.922	0.711
open field	percentage of total time in corners of arena, 20 min test	0.18198	3.6117	0.34720	0.983	0.960
open field	percentage of total time in corners, habituation ratio, 20 min test	1.8781	1.8027	0.59363	0.787	0.304
open field	percentage of total time in corners, slope, 20 min test	3.3720	1.7808	1.2333	0.499	0.0655
open field	permanence time in center of arena, 20 min test	-17.237	26.230	-0.55719	0.787	0.515
open field	permanence time in corners of arena, 20 min test	2.1975	43.338	0.34720	0.983	0.960
open field	permanence time in periphery of arena, 20 min test	17.242	26.228	0.55719	0.787	0.515
open field	total distance traveled, 20 min test	614.16	194.53	1.1566	0.0245	0.00303
open field	total number of rears, 20 min test	18.434	7.0889	0.92781	0.0875	0.0130
open field	whole arena average speed, 20 min test	0.51135	0.16192	1.1566	0.0244	0.00302
open field	whole arena resting time, 20 min test	-63.989	19.716	-1.1007	0.0191	0.00237
open field	whole arena time spent mobile, 20 min test	63.919	19.715	1.2991	0.0201	0.00239
open field	whole arena time spent vertical, 20 min test	17.486	6.7977	1.2626	0.127	0.0139
startle / PPI	average baseline movement during background noise	0.17294	1.9106	0.22394	0.995	0.929
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	-0.17706	0.066720	-1.6259	0.174	0.0136
startle / PPI	average of each corrected percent pre-pulse inhibition value	-0.15010	0.061004	-1.5282	0.218	0.0211
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-12.282	7.6199	-1.2562	0.843	0.120
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-10.739	6.1274	-1.0890	0.425	0.0919
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-19.782	8.4456	-1.8387	0.178	0.0274
startle / PPI	average startle response to full pulse (120 dB)	-28.693	77.436	-0.36300	0.876	0.714
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	3.9679	82.494	0.28327	0.982	0.962
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	5.2530	72.751	0.29496	0.968	0.943
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	29.448	68.481	0.89431	0.809	0.671
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	-2.0731	1.7769	-1.3870	0.773	0.254
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	1.5538	2.8350	0.88184	0.913	0.588
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	-4.1484	3.0069	-2.0179	0.626	0.180
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.14919	0.083877	-1.2973	0.782	0.0875
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.065712	0.080878	-0.61873	0.717	0.424
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-0.22355	0.094778	-1.8539	0.146	0.0265
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	-29.078	77.267	-0.36750	0.871	0.710
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	6.0410	82.679	0.32879	0.973	0.942
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	1.8965	73.342	0.21963	0.990	0.980
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	31.420	68.618	0.93259	0.793	0.651
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.19746	0.091131	-1.5022	0.700	0.0400
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.091953	0.077927	-0.80348	0.600	0.249
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-0.24293	0.096771	-1.8539	0.123	0.0189
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	-99.292	263.65	-0.34065	0.871	0.710
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	51.879	283.45	0.46689	0.928	0.856
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	-8.9257	252.09	0.14270	0.981	0.972
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	140.51	233.33	1.0518	0.727	0.552
startle / PPI	maximum baseline movement during background noise	0.72272	4.1616	0.32583	0.969	0.864
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-16.910	8.4600	-1.5333	0.778	0.0566
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-10.242	6.9258	-0.98586	0.501	0.152
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-21.904	8.9136	-1.8464	0.154	0.0213
startle / PPI	maximum startle response to full pulse (120 dB)	-100.04	264.20	-0.34213	0.870	0.708
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	46.971	283.38	0.43278	0.939	0.870
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-8.2590	250.86	0.13704	0.984	0.974
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	133.42	232.59	1.0183	0.733	0.571
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	-4.9090	3.9513	-1.3171	0.726	0.226
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	0.66667	6.8601	0.21676	0.994	0.923
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	-11.172	6.9486	-2.2140	0.496	0.120

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Sex	Trait Effect	P-value
eye morphology	anterior chamber depth	females	1.0 %	1.0
eye morphology	anterior chamber depth	males	0.0 %	1.0
eye morphology	anterior chamber depth	both	1.0 %	1.0
eye morphology	bulging eye	females	1.0 %	1.0
eye morphology	bulging eye	males	0.0 %	1.0
eye morphology	bulging eye	both	1.0 %	1.00
eye morphology	cornea	females	21.0 %	0.0142
eye morphology	cornea	males	2.0 %	1.0
eye morphology	cornea	both	10.0 %	0.0269
eye morphology	cornea opacity	females	5.0 %	1.00
eye morphology	cornea opacity	males	1.0 %	1.0
eye morphology	cornea opacity	both	3.0 %	1.00
eye morphology	cornea vascularization	females	3.0 %	1.0
eye morphology	cornea vascularization	males	1.0 %	1.0
eye morphology	cornea vascularization	both	2.0 %	1.00
eye morphology	corneal deposits	females	2.0 %	1.0
eye morphology	corneal deposits	males	1.0 %	1.0
eye morphology	corneal deposits	both	1.0 %	1.00
eye morphology	corneal mineralization	females	2.0 %	1.0
eye morphology	corneal mineralization	males	1.0 %	1.0
eye morphology	corneal mineralization	both	1.0 %	1.00
eye morphology	corneal scleralization	females	3.0 %	1.00
eye morphology	corneal scleralization	males	1.0 %	1.0
eye morphology	corneal scleralization	both	2.0 %	1.00
eye morphology	corneal ulcer	females	1.0 %	1.0
eye morphology	corneal ulcer	males	1.0 %	1.0
eye morphology	corneal ulcer	both	1.0 %	1.00
eye morphology	eye closure	females	1.0 %	1.00
eye morphology	eye closure	males	0.0 %	1.0
eye morphology	eye closure	both	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	females	2.0 %	1.00
eye morphology	eye hemorrhage or blood presence	males	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	both	1.0 %	1.00
eye morphology	eyelid morphology	females	1.0 %	1.0
eye morphology	eyelid morphology	males	0.0 %	1.0
eye morphology	eyelid morphology	both	1.0 %	1.0
eye morphology	eyes (present, absent)	females	1.0 %	1.0
eye morphology	eyes (present, absent)	males	0.0 %	1.0
eye morphology	eyes (present, absent)	both	0.0 %	1.0
eye morphology	fusion between cornea and lens	females	4.0 %	1.00
eye morphology	fusion between cornea and lens	males	2.0 %	1.0
eye morphology	fusion between cornea and lens	both	3.0 %	1.00
eye morphology	iris pigmentation	females	2.0 %	1.0
eye morphology	iris pigmentation	males	1.0 %	1.0
eye morphology	iris pigmentation	both	2.0 %	1.00
eye morphology	iris transillumination	females	2.0 %	1.00
eye morphology	iris transillumination	males	1.0 %	1.0
eye morphology	iris transillumination	both	1.0 %	1.00
eye morphology	irispupil	females	4.0 %	1.00
eye morphology	irispupil	males	3.0 %	1.0
eye morphology	irispupil	both	3.0 %	1.00
eye morphology	lacrimation	females	3.0 %	1.0
eye morphology	lacrimation	males	2.0 %	1.0
eye morphology	lacrimation	both	3.0 %	1.0
eye morphology	lens	females	10.0 %	1.00
eye morphology	lens	males	8.0 %	1.0
eye morphology	lens	both	9.0 %	1.0
eye morphology	lens opacity	females	9.0 %	1.0
eye morphology	lens opacity	males	10.0 %	0.368
eye morphology	lens opacity	both	3.0 %	0.703
eye morphology	narrow eye opening	females	2.0 %	1.0
eye morphology	narrow eye opening	males	1.0 %	1.0
eye morphology	narrow eye opening	both	1.0 %	1.0
eye morphology	optic disc	females	4.0 %	1.00
eye morphology	optic disc	males	2.0 %	1.0
eye morphology	optic disc	both	3.0 %	1.00
eye morphology	persistence of hyaloid vascular system	females	12.0 %	0.218
eye morphology	persistence of hyaloid vascular system	males	11.0 %	0.333
eye morphology	persistence of hyaloid vascular system	both	6.0 %	0.247
eye morphology	pupil dilation	females	2.0 %	1.0
eye morphology	pupil dilation	males	1.0 %	1.0
eye morphology	pupil dilation	both	2.0 %	1.0
eye morphology	pupil light response	females	2.0 %	1.00
eye morphology	pupil light response	males	1.0 %	1.0
eye morphology	pupil light response	both	2.0 %	1.00
eye morphology	pupil position	females	4.0 %	1.00
eye morphology	pupil position	males	3.0 %	1.0
eye morphology	pupil position	both	4.0 %	1.00
eye morphology	pupil shape	females	3.0 %	1.00
eye morphology	pupil shape	males	2.0 %	1.0
eye morphology	pupil shape	both	3.0 %	1.00
eye morphology	retina	females	10.0 %	1.0
eye morphology	retina	males	16.0 %	1.0
eye morphology	retina	both	13.0 %	1.0
eye morphology	retinal blood vessels	females	4.0 %	1.0
eye morphology	retinal blood vessels	males	2.0 %	1.0
eye morphology	retinal blood vessels	both	3.0 %	1.0
eye morphology	retinal blood vessels pattern	females	5.0 %	1.0
eye morphology	retinal blood vessels pattern	males	2.0 %	1.0
eye morphology	retinal blood vessels pattern	both	4.0 %	1.00
eye morphology	retinal blood vessels structure	females	4.0 %	1.00
eye morphology	retinal blood vessels structure	males	2.0 %	1.0
eye morphology	retinal blood vessels structure	both	3.0 %	1.00
eye morphology	retinal pigmentation	females	12.0 %	1.0
eye morphology	retinal pigmentation	males	10.0 %	0.432
eye morphology	retinal pigmentation	both	7.0 %	0.738
eye morphology	retinal structure	females	4.0 %	1.00
eye morphology	retinal structure	males	2.0 %	1.0
eye morphology	retinal structure	both	3.0 %	1.00
eye morphology	synechia	females	4.0 %	1.0
eye morphology	synechia	males	2.0 %	1.0
eye morphology	synechia	both	3.0 %	1.00
eye morphology	vitreous	females	4.0 %	1.00
eye morphology	vitreous	males	2.0 %	1.0
eye morphology	vitreous	both	3.0 %	1.00
SHIRPA	activity body position	females	1.0 %	1.0
SHIRPA	activity body position	males	2.0 %	1.0
SHIRPA	activity body position	both	1.0 %	1.00
SHIRPA	aggression	females	0.0 %	1.00
SHIRPA	aggression	males	1.0 %	1.0
SHIRPA	aggression	both	1.0 %	1.0
SHIRPA	body length	females	0.0 %	1.0
SHIRPA	body length	males	0.0 %	1.00
SHIRPA	body length	both	0.0 %	1.00
SHIRPA	body position	females	0.0 %	1.0
SHIRPA	body position	males	1.0 %	1.0
SHIRPA	body position	both	0.0 %	1.0
SHIRPA	body thickness	females	1.0 %	1.0
SHIRPA	body thickness	males	0.0 %	1.0
SHIRPA	body thickness	both	0.0 %	1.0
SHIRPA	coat color abdomen	females	3.0 %	1.00
SHIRPA	coat color abdomen	males	21.0 %	0.0323
SHIRPA	coat color abdomen	both	9.0 %	0.110
SHIRPA	coat color back	females	0.0 %	1.0
SHIRPA	coat color back	males	0.0 %	1.00
SHIRPA	coat color back	both	0.0 %	1.00
SHIRPA	coat color head	females	0.0 %	1.0
SHIRPA	coat color head	males	0.0 %	1.00
SHIRPA	coat color head	both	0.0 %	1.0
SHIRPA	coat color pattern abdomen	females	1.0 %	1.0
SHIRPA	coat color pattern abdomen	males	24.0 %	0.00142
SHIRPA	coat color pattern abdomen	both	12.0 %	0.00459
SHIRPA	coat color pattern back	females	0.0 %	1.0
SHIRPA	coat color pattern back	males	0.0 %	1.00
SHIRPA	coat color pattern back	both	0.0 %	1.0
SHIRPA	coat color pattern head	females	0.0 %	1.0
SHIRPA	coat color pattern head	males	0.0 %	1.0
SHIRPA	coat color pattern head	both	0.0 %	1.00
SHIRPA	coat hair abdomen texture appearance	females	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	males	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	both	2.0 %	1.0
SHIRPA	coat hair back texture appearance	females	0.0 %	1.0
SHIRPA	coat hair back texture appearance	males	0.0 %	1.0
SHIRPA	coat hair back texture appearance	both	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	females	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	males	1.0 %	1.00
SHIRPA	coat hair distribution abdomen	both	1.0 %	1.00
SHIRPA	coat hair distribution back	females	0.0 %	1.0
SHIRPA	coat hair distribution back	males	0.0 %	1.0
SHIRPA	coat hair distribution back	both	0.0 %	1.0
SHIRPA	coat hair distribution head	females	1.0 %	1.00
SHIRPA	coat hair distribution head	males	1.0 %	1.0
SHIRPA	coat hair distribution head	both	1.0 %	1.0
SHIRPA	coat hair head texture appearance	females	0.0 %	1.00
SHIRPA	coat hair head texture appearance	males	0.0 %	1.0
SHIRPA	coat hair head texture appearance	both	0.0 %	1.0
SHIRPA	contact righting	females	5.0 %	1.0
SHIRPA	contact righting	males	5.0 %	1.00
SHIRPA	contact righting	both	5.0 %	1.00
SHIRPA	ear morphology	females	0.0 %	1.0
SHIRPA	ear morphology	males	0.0 %	1.0
SHIRPA	ear morphology	both	0.0 %	1.0
SHIRPA	fat distribution	females	0.0 %	1.0
SHIRPA	fat distribution	males	0.0 %	1.0
SHIRPA	fat distribution	both	0.0 %	1.00
SHIRPA	forelimb digit number	females	0.0 %	1.00
SHIRPA	forelimb digit number	males	0.0 %	1.0
SHIRPA	forelimb digit number	both	0.0 %	1.00
SHIRPA	forelimb digit position	females	0.0 %	1.0
SHIRPA	forelimb digit position	males	0.0 %	1.0
SHIRPA	forelimb digit position	both	0.0 %	1.0
SHIRPA	forelimb digit shape	females	0.0 %	1.0
SHIRPA	forelimb digit shape	males	0.0 %	1.0
SHIRPA	forelimb digit shape	both	0.0 %	1.0
SHIRPA	forelimb digit size	females	0.0 %	1.0
SHIRPA	forelimb digit size	males	0.0 %	1.0
SHIRPA	forelimb digit size	both	0.0 %	1.0
SHIRPA	forelimb footpads	females	0.0 %	1.0
SHIRPA	forelimb footpads	males	0.0 %	1.0
SHIRPA	forelimb footpads	both	0.0 %	1.0
SHIRPA	forelimb nail length	females	0.0 %	1.0
SHIRPA	forelimb nail length	males	0.0 %	1.0
SHIRPA	forelimb nail length	both	0.0 %	1.0
SHIRPA	forelimb nail number	females	0.0 %	1.0
SHIRPA	forelimb nail number	males	0.0 %	1.0
SHIRPA	forelimb nail number	both	0.0 %	1.0
SHIRPA	forelimb nail position	females	0.0 %	1.0
SHIRPA	forelimb nail position	males	0.0 %	1.0
SHIRPA	forelimb nail position	both	0.0 %	1.0
SHIRPA	forelimb nail shape	females	0.0 %	1.0
SHIRPA	forelimb nail shape	males	0.0 %	1.0
SHIRPA	forelimb nail shape	both	0.0 %	1.0
SHIRPA	forelimbs position	females	0.0 %	1.0
SHIRPA	forelimbs position	males	0.0 %	1.0
SHIRPA	forelimbs position	both	0.0 %	1.0
SHIRPA	forelimbs shape	females	0.0 %	1.0
SHIRPA	forelimbs shape	males	0.0 %	1.0
SHIRPA	forelimbs shape	both	0.0 %	1.0
SHIRPA	forelimbs size	females	0.0 %	1.0
SHIRPA	forelimbs size	males	0.0 %	1.0
SHIRPA	forelimbs size	both	0.0 %	1.0
SHIRPA	forepaw position	females	0.0 %	1.0
SHIRPA	forepaw position	males	0.0 %	1.0
SHIRPA	forepaw position	both	0.0 %	1.0
SHIRPA	forepaw shape	females	0.0 %	1.0
SHIRPA	forepaw shape	males	0.0 %	1.0
SHIRPA	forepaw shape	both	0.0 %	1.0
SHIRPA	forepaw size	females	0.0 %	1.0
SHIRPA	forepaw size	males	0.0 %	1.0
SHIRPA	forepaw size	both	0.0 %	1.0
SHIRPA	gait (fluidity)	females	0.0 %	1.0
SHIRPA	gait (fluidity)	males	0.0 %	1.00
SHIRPA	gait (fluidity)	both	0.0 %	1.00
SHIRPA	genitalia morphology	females	0.0 %	1.00
SHIRPA	genitalia morphology	males	0.0 %	1.0
SHIRPA	genitalia morphology	both	0.0 %	1.00
SHIRPA	genitalia presence	females	0.0 %	1.0
SHIRPA	genitalia presence	males	0.0 %	1.0
SHIRPA	genitalia presence	both	0.0 %	1.0
SHIRPA	genitalia size	females	0.0 %	1.0
SHIRPA	genitalia size	males	0.0 %	1.0
SHIRPA	genitalia size	both	0.0 %	1.0
SHIRPA	head bobbing	females	0.0 %	1.0
SHIRPA	head bobbing	males	0.0 %	1.0
SHIRPA	head bobbing	both	0.0 %	1.0
SHIRPA	head morphology	females	0.0 %	1.0
SHIRPA	head morphology	males	0.0 %	1.00
SHIRPA	head morphology	both	0.0 %	1.0
SHIRPA	head size	females	0.0 %	1.0
SHIRPA	head size	males	0.0 %	1.0
SHIRPA	head size	both	0.0 %	1.00
SHIRPA	hindlimb digit number	females	1.0 %	1.00
SHIRPA	hindlimb digit number	males	0.0 %	1.0
SHIRPA	hindlimb digit number	both	0.0 %	1.00
SHIRPA	hindlimb digit position	females	0.0 %	1.0
SHIRPA	hindlimb digit position	males	0.0 %	1.0
SHIRPA	hindlimb digit position	both	0.0 %	1.0
SHIRPA	hindlimb digit shape	females	12.0 %	0.0175
SHIRPA	hindlimb digit shape	males	0.0 %	1.0
SHIRPA	hindlimb digit shape	both	6.0 %	0.0349
SHIRPA	hindlimb digit size	females	0.0 %	1.00
SHIRPA	hindlimb digit size	males	0.0 %	1.0
SHIRPA	hindlimb digit size	both	0.0 %	1.00
SHIRPA	hindlimb nail length	females	0.0 %	1.0
SHIRPA	hindlimb nail length	males	0.0 %	1.0
SHIRPA	hindlimb nail length	both	0.0 %	1.00
SHIRPA	hindlimb nail number	females	0.0 %	1.0
SHIRPA	hindlimb nail number	males	1.0 %	1.0
SHIRPA	hindlimb nail number	both	0.0 %	1.00
SHIRPA	hindlimb nail position	females	0.0 %	1.0
SHIRPA	hindlimb nail position	males	0.0 %	1.0
SHIRPA	hindlimb nail position	both	0.0 %	1.0
SHIRPA	hindlimb nail shape	females	0.0 %	1.0
SHIRPA	hindlimb nail shape	males	0.0 %	1.0
SHIRPA	hindlimb nail shape	both	0.0 %	1.0
SHIRPA	hindlimbs footpads	females	0.0 %	1.0
SHIRPA	hindlimbs footpads	males	0.0 %	1.0
SHIRPA	hindlimbs footpads	both	0.0 %	1.0
SHIRPA	hindlimbs position	females	0.0 %	1.0
SHIRPA	hindlimbs position	males	0.0 %	1.0
SHIRPA	hindlimbs position	both	0.0 %	1.0
SHIRPA	hindlimbs shape	females	0.0 %	1.0
SHIRPA	hindlimbs shape	males	0.0 %	1.0
SHIRPA	hindlimbs shape	both	0.0 %	1.0
SHIRPA	hindlimbs size	females	0.0 %	1.0
SHIRPA	hindlimbs size	males	0.0 %	1.0
SHIRPA	hindlimbs size	both	0.0 %	1.0
SHIRPA	hindpaw position	females	0.0 %	1.0
SHIRPA	hindpaw position	males	0.0 %	1.0
SHIRPA	hindpaw position	both	0.0 %	1.0
SHIRPA	hindpaw shape	females	0.0 %	1.0
SHIRPA	hindpaw shape	males	0.0 %	1.0
SHIRPA	hindpaw shape	both	0.0 %	1.0
SHIRPA	hindpaw size	females	0.0 %	1.0
SHIRPA	hindpaw size	males	0.0 %	1.0
SHIRPA	hindpaw size	both	0.0 %	1.0
SHIRPA	limb grasp	females	9.0 %	1.00
SHIRPA	limb grasp	males	6.0 %	1.0
SHIRPA	limb grasp	both	7.0 %	0.624
SHIRPA	lower lip morphology	females	0.0 %	1.0
SHIRPA	lower lip morphology	males	0.0 %	1.0
SHIRPA	lower lip morphology	both	0.0 %	1.0
SHIRPA	lower teeth appearance	females	0.0 %	1.0
SHIRPA	lower teeth appearance	males	0.0 %	1.00
SHIRPA	lower teeth appearance	both	0.0 %	1.00
SHIRPA	mouth morphology	females	0.0 %	1.0
SHIRPA	mouth morphology	males	0.0 %	1.00
SHIRPA	mouth morphology	both	0.0 %	1.00
SHIRPA	salivation	females	0.0 %	1.0
SHIRPA	salivation	males	0.0 %	1.0
SHIRPA	salivation	both	0.0 %	1.0
SHIRPA	skin color back paws	females	0.0 %	1.0
SHIRPA	skin color back paws	males	0.0 %	1.0
SHIRPA	skin color back paws	both	0.0 %	1.0
SHIRPA	skin color ear	females	0.0 %	1.0
SHIRPA	skin color ear	males	0.0 %	1.0
SHIRPA	skin color ear	both	0.0 %	1.0
SHIRPA	skin color front paws	females	0.0 %	1.0
SHIRPA	skin color front paws	males	0.0 %	1.0
SHIRPA	skin color front paws	both	0.0 %	1.0
SHIRPA	skin color snout	females	0.0 %	1.0
SHIRPA	skin color snout	males	0.0 %	1.0
SHIRPA	skin color snout	both	0.0 %	1.0
SHIRPA	skin color tail	females	0.0 %	1.0
SHIRPA	skin color tail	males	0.0 %	1.0
SHIRPA	skin color tail	both	0.0 %	1.0
SHIRPA	skin color whole body	females	0.0 %	1.0
SHIRPA	skin color whole body	males	0.0 %	1.0
SHIRPA	skin color whole body	both	0.0 %	1.0
SHIRPA	skin texture back paw	females	0.0 %	1.0
SHIRPA	skin texture back paw	males	0.0 %	1.0
SHIRPA	skin texture back paw	both	0.0 %	1.0
SHIRPA	skin texture ear	females	0.0 %	1.0
SHIRPA	skin texture ear	males	0.0 %	1.0
SHIRPA	skin texture ear	both	0.0 %	1.0
SHIRPA	skin texture front paws	females	0.0 %	1.0
SHIRPA	skin texture front paws	males	0.0 %	1.0
SHIRPA	skin texture front paws	both	0.0 %	1.0
SHIRPA	skin texture snout	females	0.0 %	1.0
SHIRPA	skin texture snout	males	0.0 %	1.0
SHIRPA	skin texture snout	both	0.0 %	1.0
SHIRPA	skin texture tail	females	0.0 %	1.0
SHIRPA	skin texture tail	males	0.0 %	1.0
SHIRPA	skin texture tail	both	0.0 %	1.0
SHIRPA	skin texture whole body	females	0.0 %	1.0
SHIRPA	skin texture whole body	males	0.0 %	1.00
SHIRPA	skin texture whole body	both	0.0 %	1.00
SHIRPA	snout size	females	0.0 %	1.0
SHIRPA	snout size	males	1.0 %	1.0
SHIRPA	snout size	both	0.0 %	1.0
SHIRPA	startle response	females	0.0 %	1.00
SHIRPA	startle response	males	0.0 %	1.00
SHIRPA	startle response	both	0.0 %	1.00
SHIRPA	tail curvature	females	0.0 %	1.00
SHIRPA	tail curvature	males	0.0 %	1.0
SHIRPA	tail curvature	both	0.0 %	1.0
SHIRPA	tail elevation	females	1.0 %	1.00
SHIRPA	tail elevation	males	2.0 %	1.0
SHIRPA	tail elevation	both	1.0 %	1.0
SHIRPA	tail length	females	0.0 %	1.0
SHIRPA	tail length	males	0.0 %	1.0
SHIRPA	tail length	both	0.0 %	1.00
SHIRPA	tail morphology	females	0.0 %	1.00
SHIRPA	tail morphology	males	0.0 %	1.0
SHIRPA	tail morphology	both	0.0 %	1.00
SHIRPA	tail presence	females	0.0 %	1.0
SHIRPA	tail presence	males	0.0 %	1.0
SHIRPA	tail presence	both	0.0 %	1.0
SHIRPA	tail shape	females	0.0 %	1.0
SHIRPA	tail shape	males	0.0 %	1.0
SHIRPA	tail shape	both	0.0 %	1.00
SHIRPA	tail thickness	females	0.0 %	1.0
SHIRPA	tail thickness	males	0.0 %	1.0
SHIRPA	tail thickness	both	0.0 %	1.0
SHIRPA	teeth presence	females	0.0 %	1.0
SHIRPA	teeth presence	males	0.0 %	1.00
SHIRPA	teeth presence	both	0.0 %	1.00
SHIRPA	transfer arousal	females	1.0 %	1.0
SHIRPA	transfer arousal	males	2.0 %	1.00
SHIRPA	transfer arousal	both	1.0 %	1.0
SHIRPA	tremor	females	0.0 %	1.0
SHIRPA	tremor	males	0.0 %	1.0
SHIRPA	tremor	both	0.0 %	1.00
SHIRPA	trunk curl	females	0.0 %	1.00
SHIRPA	trunk curl	males	0.0 %	1.0
SHIRPA	trunk curl	both	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	females	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	males	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	both	0.0 %	1.00
SHIRPA	upper lip morphology	females	0.0 %	1.0
SHIRPA	upper lip morphology	males	0.0 %	1.0
SHIRPA	upper lip morphology	both	0.0 %	1.0
SHIRPA	upper teeth appearance	females	0.0 %	1.0
SHIRPA	upper teeth appearance	males	0.0 %	1.0
SHIRPA	upper teeth appearance	both	0.0 %	1.00
SHIRPA	vibrissae appearance	females	2.0 %	1.0
SHIRPA	vibrissae appearance	males	1.0 %	1.0
SHIRPA	vibrissae appearance	both	1.0 %	1.0
SHIRPA	vibrissae presence	females	2.0 %	1.00
SHIRPA	vibrissae presence	males	1.0 %	1.0
SHIRPA	vibrissae presence	both	2.0 %	1.0
SHIRPA	vocalization	females	2.0 %	1.00
SHIRPA	vocalization	males	2.0 %	1.0
SHIRPA	vocalization	both	2.0 %	1.00

GENOTYPE CORRELATION PLOT

Correlate Gramd1b^em1(IMPC)J/Mmjax -/+ with genotype: