MPD: JaxKOMP-EAP genotype: C530008M17Rik<sup>em1(IMPC)J</sup>/Mmjax -/-

JaxKOMP-EAP effect sizes: C530008M17Rik^em1(IMPC)J/Mmjax -/- Gene C530008M17Rik

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

In this plot, data points are the computed genotype effect size vs. C57BL/6NJ controls, for all measured numeric phenotypes in JaxKOMP-EAP

Dimensions Width: × Height: px

Plot Options Group by Procedure Standard Error Show Effect Sizes RankZ

Significance Threshold p-Value Threshold Adjusted Unadjusted

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Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value

ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	2.9167	1.6351	0.61247	0.490	0.102
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	-2.4850	1.8353	-0.71105	0.558	0.203
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	1.6667	3.8370	0.15046	0.878	0.672
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	4.6200	3.3440	0.70292	0.579	0.195
body composition	body length	0.069977	0.043226	1.1245	0.371	0.118
body composition	body weight (at time of DXA)	-2.4356	0.74736	-1.4197	0.0241	0.00302
body composition	bone area, whole body scan, head excluded	0.38394	0.19252	1.7472	0.232	0.0567
body composition	bone mineral content of whole body scan, head excluded	0.031017	0.014175	1.8579	0.187	0.0378
body composition	bone mineral content to body weight ratio	0.0015820	0.00056912	2.1100	0.0789	0.00998
body composition	bone mineral density of whole body scan, head excluded	0.0012731	0.00071091	1.3446	0.308	0.0850
body composition	fat tissue mass of whole body scan, head excluded	-0.85424	0.53249	-1.5647	0.334	0.121
body composition	fat tissue mass to body weight ratio	-0.038153	0.015029	-1.7286	0.0982	0.0172
body composition	lean tissue mass of whole body scan, head excluded	0.29902	0.38424	0.47918	0.728	0.443
body composition	lean tissue mass to body weight ratio	0.038587	0.012653	1.7859	0.0572	0.00509
body composition	percent fat, whole body scan, head excluded	-3.8127	1.4497	-1.8503	0.0906	0.0139
body composition	ratio of soft-tissue attenuation coefficients	0.0043849	0.0015811	1.9051	0.0746	0.00994
body composition	tissue area	-0.40770	0.28113	-1.1249	0.434	0.159
body composition	total tissue mass, whole body scan, head excluded	-0.45479	0.51646	-1.3449	0.636	0.387
clinical blood chemistry	alanine transaminase (plasma ALT)	12.562	3.8757	0.87397	0.121	0.00453
clinical blood chemistry	albumin (plasma Alb)	-1.9439	0.33249	-2.1757	0.00339	0.0000155
clinical blood chemistry	alkaline phosphatase (plasma ALP)	-9.5837	5.1775	-1.9820	0.256	0.0798
clinical blood chemistry	aspartate transaminase (plasma AST)	5.1797	5.8270	0.25218	0.694	0.386
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	-0.50036	0.22205	-1.4294	0.323	0.0369
clinical blood chemistry	blood urea nitrogen (BUN)	7.3075	1.5751	2.4645	0.00665	0.000179
clinical blood chemistry	creatinine (plasma)	0.066073	0.018042	1.5944	0.0277	0.00178
clinical blood chemistry	glucose (plasma GLU, no fast)	20.575	12.848	1.1002	0.299	0.126
clinical blood chemistry	HDL cholesterol (plasma HDL)	-3.7392	4.9582	-1.0974	0.739	0.461
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	-0.018100	0.0079307	-1.0972	0.238	0.0342
clinical blood chemistry	phosphorus (plasma phosphate)	2.3638	0.25093	2.2591	0.00000600	1.37e-8
clinical blood chemistry	total bilirubin (plasma TBIL)	-0.0070000	0.010911	-0.53715	0.796	0.529
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	-3.5733	6.8301	-0.83475	0.839	0.607
clinical blood chemistry	total protein (plasma TP)	-2.3842	0.66267	-1.6778	0.0390	0.00206
clinical blood chemistry	triglyceride (plasma TG, no fast)	60.039	13.847	2.3376	0.0211	0.000398
EKG	duration of PQ interval	-0.17983	0.82498	-0.026198	0.954	0.829
EKG	duration of PR interval	0.10700	0.91816	0.18850	0.982	0.908
EKG	duration of QRS interval	0.45082	0.37524	1.1721	0.885	0.241
EKG	duration of QT interval	0.15014	1.1454	0.30911	0.985	0.897
EKG	duration of QTC interval, calculated by dividing QT interval by square root of preceding RR interval	0.60001	1.1810	0.72861	0.938	0.616
EKG	duration of RR interval	-1.0392	1.4756	-0.29015	0.814	0.488
EKG	duration of ST interval	-0.53836	1.1809	-0.31970	0.915	0.653
EKG	heart rate coefficient of variation (signal intensity)	1.2381	1.2670	1.0955	0.867	0.339
EKG	heart rate variability, mean of differences between sequential beats; beats per min	8.0404	9.1637	0.99459	0.867	0.389
EKG	heart rate, beats per min	9.9757	12.935	0.34876	0.785	0.448
EKG	mean R amplitude, mean amplitude of signal measured from isoelectric line to peak of QRS	-0.13586	0.10355	-1.2043	0.580	0.202
EKG	mean SR amplitude, mean amplitude of signal measured from signal minimum line to peak of QRS	-0.16893	0.11513	-1.0449	0.516	0.155
EKG	number of signals	-9.6997	4.5713	-1.6464	0.480	0.0444
EKG	proportion of number pairs of successive beat-to-beat intervals that exceed 50 ms	1.8463	1.5623	0.41663	0.814	0.249
EKG	QT dispersion, measured as inter-lead variability of QT intervals	1.3378	5.5050	0.40799	0.977	0.810
EKG	QTc dispersion, calculated as rate-corrected QT dispersion	2.1008	6.1859	0.52949	0.966	0.737
EKG	root mean square of successive differences of neighboring RR intervals	0.95378	3.0085	0.63948	0.947	0.754
glucose tolerance test	amount glucose injected	-2.5713	3.0041	-0.39133	0.741	0.400
glucose tolerance test	plasma glucose, 0min	5.3863	4.6177	0.31539	0.466	0.253
glucose tolerance test	plasma glucose, 15min	-11.403	19.807	-0.21862	0.829	0.569
glucose tolerance test	plasma glucose, 30min	-9.7100	21.789	-0.17105	0.855	0.659
glucose tolerance test	plasma glucose, 60min	13.577	15.031	0.65650	0.700	0.374
glucose tolerance test	plasma glucose, 120min	7.1504	8.8739	0.34293	0.695	0.427
grip strength	body weight (at time of grip strength test)	0.17205	0.48281	0.36788	0.838	0.724
grip strength	forelimb and hindlimb grip strength (mean of trials), average	19.764	7.3495	1.6354	0.0594	0.0110
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	0.98680	0.35669	1.5673	0.0561	0.00921
grip strength	forelimb and hindlimb grip strength by trial, trial1	2.4312	10.007	0.39802	0.930	0.810
grip strength	forelimb and hindlimb grip strength by trial, trial2	36.393	10.939	2.2518	0.0332	0.00212
grip strength	forelimb and hindlimb grip strength by trial, trial3	20.466	10.251	1.4793	0.231	0.0539
grip strength	forelimb grip strength (mean of trials), average	5.0661	4.1129	0.95972	0.487	0.226
grip strength	forelimb grip strength (mean of trials), average normalized to bw	0.30040	0.20500	1.0238	0.400	0.152
grip strength	forelimb grip strength by trial, trial1	-0.16274	6.1330	0.27048	0.990	0.979
grip strength	forelimb grip strength by trial, trial2	9.6668	6.1613	1.2511	0.424	0.126
grip strength	forelimb grip strength by trial, trial3	5.6942	6.3114	0.84204	0.697	0.373
heart weight	heart weight, normalized to body weight	-0.26611	0.29982	-1.4633	0.601	0.388
heart weight	heart weight, weight	-3.8606	6.8118	-0.89683	0.747	0.579
hematology	basophil differential (percent of total WBC)	0.0055556	0.042583	0.11557	0.982	0.898
hematology	calculated hemoglobin (cHGB)	-0.51250	0.18150	-1.4755	0.126	0.0144
hematology	eosinophil differential (percent of total WBC)	-0.13056	0.46612	-0.28768	0.932	0.784
hematology	hematocrit (HCT)	0.41822	0.70685	0.080726	0.765	0.564
hematology	hemoglobin concentration distribution width (HDW)	-0.080022	0.029092	-1.9488	0.158	0.0176
hematology	large unstained cells (percent of total WBC)	-0.020181	0.054459	-0.11053	0.887	0.717
hematology	lymphocyte differential (percent of total WBC)	-0.14704	1.9170	-0.10544	0.968	0.940
hematology	mean corpuscular hemoglobin (CHr)	0.0055556	0.077889	0.064335	0.971	0.944
hematology	mean platelet volume (MPV)	0.010278	0.074042	-0.12172	0.950	0.892
hematology	mean RBC corpuscular hemoglobin (MCH)	0.29306	0.17882	1.0571	0.456	0.125
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	-0.74664	0.38708	-1.0907	0.370	0.0759
hematology	mean RBC corpuscular volume (MCV)	1.8908	0.43522	2.3771	0.00900	0.000795
hematology	measured hemoglobin (mHGB)	-0.20625	0.22450	-0.72916	0.660	0.375
hematology	monocyte differential (percent of total WBC)	0.11764	0.19928	0.61311	0.824	0.565
hematology	neutrophil differential (percent of total WBC)	0.16919	1.7870	0.097192	0.966	0.926
hematology	platelet count (PLT; units per volume x 10³)	-53.396	68.864	-0.64813	0.757	0.452
hematology	RBC corpuscular distribution width (RDW)	0.46319	0.22312	1.3917	0.235	0.0583
hematology	RBC corpuscular hemoglobin concentration mean (CHCM)	-1.3641	0.31451	-2.6995	0.0130	0.000806
hematology	red blood cell count (RBC; per volume x 10⁶)	-0.33653	0.15577	-1.5231	0.235	0.0500
hematology	reticulocyte count (Retic; units per volume x 10⁹)	12.015	31.579	0.62070	0.908	0.710
hematology	reticulocyte differential (percent of total RBC)	0.22000	0.31363	1.0870	0.781	0.495
hematology	white blood cell count (WBC; units per volume x 10³)	0.83806	0.85176	0.73673	0.553	0.343
holeboard	number of hole pokes by individual hole number, 20 min test, 1	-0.067468	0.56405	-0.0025320	0.974	0.905
holeboard	number of hole pokes by individual hole number, 20 min test, 2	-1.1046	0.45058	-1.5962	0.362	0.0173
holeboard	number of hole pokes by individual hole number, 20 min test, 3	0.71168	0.37641	1.1329	0.596	0.0637
holeboard	number of hole pokes by individual hole number, 20 min test, 4	-0.49183	0.84078	-0.43443	0.866	0.561
holeboard	number of hole pokes by individual hole number, 20 min test, 5	0.076633	0.46225	0.23075	0.970	0.869
holeboard	number of hole pokes by individual hole number, 20 min test, 6	0.13266	0.28459	0.40008	0.939	0.643
holeboard	number of hole pokes by individual hole number, 20 min test, 7	-0.21310	0.27093	-0.61161	0.902	0.435
holeboard	number of hole pokes by individual hole number, 20 min test, 8	0.22299	0.48471	0.50801	0.930	0.647
holeboard	number of hole pokes by individual hole number, 20 min test, 9	0.41910	0.43200	0.84596	0.797	0.336
holeboard	number of hole pokes by individual hole number, 20 min test, 10	-0.12877	0.24946	-0.28985	0.935	0.608
holeboard	number of hole pokes by individual hole number, 20 min test, 11	0.19917	0.23203	0.51898	0.839	0.394
holeboard	number of hole pokes by individual hole number, 20 min test, 12	0.10368	0.43411	0.28905	0.960	0.812
holeboard	number of hole pokes by individual hole number, 20 min test, 13	0.25061	0.59572	0.32975	0.908	0.676
holeboard	number of hole pokes by individual hole number, 20 min test, 14	-0.44786	0.38167	-0.63581	0.682	0.245
holeboard	number of hole pokes by individual hole number, 20 min test, 15	-0.31962	0.38272	-0.42211	0.815	0.407
holeboard	number of hole pokes by individual hole number, 20 min test, 16	0.18246	0.78922	0.19006	0.948	0.818
holeboard	total number of hole pokes, 20 min test	-0.26252	3.7552	0.052316	0.972	0.945
light / dark	fecal boli count, 20 min test	-0.86396	0.69830	-0.93239	0.626	0.223
light / dark	latency to enter dark zone, 20 min test	2.2587	32.043	-0.070363	0.981	0.944
light / dark	number of transitions between light and dark zones, 20 min test	1.4045	6.3681	0.24721	0.929	0.826
light / dark	percentage of total time in dark zone, 20 min test	3.0678	2.8593	0.66687	0.649	0.288
light / dark	percentage of total time in light zone, 20 min test	-3.0678	2.8593	-0.66856	0.648	0.288
light / dark	time mobile in dark zone, 20 min test	43.060	12.044	1.7455	0.0154	0.000713
light / dark	time mobile in light zone, 20 min test	8.6223	10.531	0.31757	0.673	0.416
light / dark	time spent in dark zone, 20 min test	30.414	42.257	0.67704	0.812	0.475
light / dark	time spent in light zone, 20 min test	-30.414	42.257	-0.67704	0.812	0.475
open field	average speed in center of arena, 20 min test	0.51078	0.33223	0.79914	0.445	0.130
open field	average speed in periphery of arena, 20 min test	0.70342	0.15556	1.7185	0.000809	0.0000308
open field	distance traveled habituation ratio, 20 min test	-12.516	9.2544	-1.0481	0.498	0.181
open field	distance traveled in center of arena, 20 min test	187.49	94.467	0.81588	0.199	0.0519
open field	distance traveled in periphery of arena, 20 min test	676.09	159.03	1.7185	0.00206	0.0000782
open field	distance traveled slope, 20 min test	-12.263	8.7746	-1.0693	0.486	0.168
open field	distance traveled, 20 min test, 1st 5min	299.76	85.817	1.7127	0.0142	0.000921
open field	distance traveled, 20 min test, 2nd 5min	208.54	57.984	1.5504	0.00988	0.000667
open field	distance traveled, 20 min test, 3rd 5min	178.60	46.799	1.3815	0.00679	0.000331
open field	distance traveled, 20 min test, 4th 5min	187.10	53.205	1.3992	0.0117	0.000856
open field	number of clockwise revolution episodes, 20 min test	2.9671	1.0786	1.1828	0.0971	0.00791
open field	number of counter-clockwise revolution episodes, 20 min test	3.8690	1.7019	1.4826	0.181	0.0267
open field	number of fecal boli, 20 min test	-0.30000	1.4183	0.038856	0.928	0.834
open field	number of rears in 5 min bins, 20 min test, 1st 5min	0.29696	2.2899	-0.14016	0.954	0.897
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	2.2977	2.5702	0.24199	0.652	0.375
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	4.2499	2.6806	0.68252	0.362	0.118
open field	number of rears in 5 min bins, 20 min test, 4th 5min	0.098721	2.9019	-0.34292	0.989	0.973
open field	percentage of total time in center of arena, 20 min test	1.5794	2.3411	0.16113	0.776	0.503
open field	percentage of total time in center of arena, slope, 20 min test	0.41876	0.94637	0.35148	0.922	0.660
open field	percentage of total time in center, habituation ratio, 20 min test	0.36635	0.93675	0.31035	0.913	0.697
open field	percentage of total time in corners of arena, 20 min test	-5.5869	4.0623	-0.74488	0.483	0.174
open field	percentage of total time in corners, habituation ratio, 20 min test	-0.45439	1.4855	-0.49247	0.957	0.761
open field	percentage of total time in corners, slope, 20 min test	0.045509	1.5052	-0.24753	0.996	0.976
open field	permanence time in center of arena, 20 min test	18.965	28.091	0.16250	0.777	0.502
open field	permanence time in corners of arena, 20 min test	-67.051	48.746	-0.74488	0.484	0.174
open field	permanence time in periphery of arena, 20 min test	-18.957	28.096	-0.16250	0.777	0.503
open field	total distance traveled, 20 min test	874.19	197.44	1.6625	0.00101	0.0000427
open field	total number of rears, 20 min test	6.8319	9.0912	0.13805	0.692	0.455
open field	whole arena average speed, 20 min test	0.72957	0.16437	1.6679	0.000971	0.0000411
open field	whole arena resting time, 20 min test	-86.050	18.023	-1.5549	0.000337	0.0000126
open field	whole arena time spent mobile, 20 min test	86.149	18.016	1.7364	0.000343	0.0000123
open field	whole arena time spent vertical, 20 min test	-0.50872	8.1053	-0.15298	0.982	0.950
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	-1.5811	2.1649	-0.46658	0.737	0.471

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

In this plot, data points are the computed genotype effect % vs. C57BL/6NJ controls, for all measured categorical phenotypes in JaxKOMP-EAP

Dimensions Width: × Height: px

Plot Options Group by Procedure

Include Sexes Data Both Females Males

Significance Threshold p-Value Threshold

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Procedure	JaxKOMP-EAP Trait	Sex	Trait Effect	P-value

eye morphology	anterior chamber depth	females	1.0 %	1.0
eye morphology	anterior chamber depth	males	14.0 %	0.0372
eye morphology	anterior chamber depth	both	6.0 %	0.133
eye morphology	bulging eye	females	1.0 %	1.0
eye morphology	bulging eye	males	14.0 %	0.0337
eye morphology	bulging eye	both	6.0 %	0.109
eye morphology	cornea	females	4.0 %	1.0
eye morphology	cornea	males	14.0 %	0.0693
eye morphology	cornea	both	6.0 %	0.157
eye morphology	cornea opacity	females	5.0 %	1.00
eye morphology	cornea opacity	males	27.0 %	0.000630
eye morphology	cornea opacity	both	10.0 %	0.0300
eye morphology	cornea vascularization	females	3.0 %	1.0
eye morphology	cornea vascularization	males	14.0 %	0.0513
eye morphology	cornea vascularization	both	6.0 %	0.221
eye morphology	corneal deposits	females	2.0 %	1.0
eye morphology	corneal deposits	males	14.0 %	0.0687
eye morphology	corneal deposits	both	6.0 %	0.197
eye morphology	corneal mineralization	females	2.0 %	1.0
eye morphology	corneal mineralization	males	14.0 %	0.0518
eye morphology	corneal mineralization	both	6.0 %	0.189
eye morphology	corneal scleralization	females	3.0 %	1.00
eye morphology	corneal scleralization	males	14.0 %	0.0834
eye morphology	corneal scleralization	both	6.0 %	0.190
eye morphology	corneal ulcer	females	1.0 %	1.0
eye morphology	corneal ulcer	males	14.0 %	0.0438
eye morphology	corneal ulcer	both	6.0 %	0.144
eye morphology	eye closure	females	1.0 %	1.00
eye morphology	eye closure	males	14.0 %	0.0336
eye morphology	eye closure	both	6.0 %	0.108
eye morphology	eye hemorrhage or blood presence	females	2.0 %	1.00
eye morphology	eye hemorrhage or blood presence	males	14.0 %	0.0462
eye morphology	eye hemorrhage or blood presence	both	6.0 %	0.152
eye morphology	eyelid morphology	females	1.0 %	1.0
eye morphology	eyelid morphology	males	14.0 %	0.0336
eye morphology	eyelid morphology	both	6.0 %	0.116
eye morphology	eyes (present, absent)	females	1.0 %	1.0
eye morphology	eyes (present, absent)	males	0.0 %	1.0
eye morphology	eyes (present, absent)	both	0.0 %	1.0
eye morphology	fusion between cornea and lens	females	4.0 %	1.00
eye morphology	fusion between cornea and lens	males	13.0 %	0.124
eye morphology	fusion between cornea and lens	both	5.0 %	0.347
eye morphology	iris pigmentation	females	2.0 %	1.0
eye morphology	iris pigmentation	males	14.0 %	0.0563
eye morphology	iris pigmentation	both	6.0 %	0.206
eye morphology	iris transillumination	females	2.0 %	1.00
eye morphology	iris transillumination	males	14.0 %	0.0488
eye morphology	iris transillumination	both	6.0 %	0.181
eye morphology	irispupil	females	4.0 %	1.00
eye morphology	irispupil	males	14.0 %	0.0550
eye morphology	irispupil	both	6.0 %	0.212
eye morphology	lacrimation	females	3.0 %	1.0
eye morphology	lacrimation	males	13.0 %	0.124
eye morphology	lacrimation	both	6.0 %	0.331
eye morphology	lens	females	10.0 %	1.00
eye morphology	lens	males	13.0 %	0.188
eye morphology	lens	both	6.0 %	0.449
eye morphology	lens opacity	females	9.0 %	1.0
eye morphology	lens opacity	males	23.0 %	0.0293
eye morphology	lens opacity	both	6.0 %	0.214
eye morphology	narrow eye opening	females	2.0 %	1.0
eye morphology	narrow eye opening	males	14.0 %	0.0437
eye morphology	narrow eye opening	both	6.0 %	0.199
eye morphology	optic disc	females	4.0 %	1.00
eye morphology	optic disc	males	13.0 %	0.152
eye morphology	optic disc	both	5.0 %	0.394
eye morphology	persistence of hyaloid vascular system	females	14.0 %	1.0
eye morphology	persistence of hyaloid vascular system	males	38.0 %	0.00480
eye morphology	persistence of hyaloid vascular system	both	11.0 %	0.199
eye morphology	pupil dilation	females	2.0 %	1.0
eye morphology	pupil dilation	males	14.0 %	0.0711
eye morphology	pupil dilation	both	6.0 %	0.223
eye morphology	pupil light response	females	2.0 %	1.00
eye morphology	pupil light response	males	14.0 %	0.0637
eye morphology	pupil light response	both	6.0 %	0.223
eye morphology	pupil position	females	4.0 %	1.00
eye morphology	pupil position	males	14.0 %	0.0560
eye morphology	pupil position	both	6.0 %	0.224
eye morphology	pupil shape	females	3.0 %	1.00
eye morphology	pupil shape	males	14.0 %	0.0771
eye morphology	pupil shape	both	6.0 %	0.236
eye morphology	retina	females	10.0 %	1.0
eye morphology	retina	males	13.0 %	0.300
eye morphology	retina	both	6.0 %	0.594
eye morphology	retinal blood vessels	females	4.0 %	1.0
eye morphology	retinal blood vessels	males	13.0 %	0.131
eye morphology	retinal blood vessels	both	5.0 %	0.360
eye morphology	retinal blood vessels pattern	females	5.0 %	1.0
eye morphology	retinal blood vessels pattern	males	13.0 %	0.156
eye morphology	retinal blood vessels pattern	both	5.0 %	0.423
eye morphology	retinal blood vessels structure	females	4.0 %	1.00
eye morphology	retinal blood vessels structure	males	13.0 %	0.140
eye morphology	retinal blood vessels structure	both	5.0 %	0.375
eye morphology	retinal pigmentation	females	12.0 %	1.0
eye morphology	retinal pigmentation	males	13.0 %	0.297
eye morphology	retinal pigmentation	both	6.0 %	0.567
eye morphology	retinal structure	females	4.0 %	1.00
eye morphology	retinal structure	males	13.0 %	0.145
eye morphology	retinal structure	both	5.0 %	0.380
eye morphology	synechia	females	4.0 %	1.0
eye morphology	synechia	males	13.0 %	0.126
eye morphology	synechia	both	5.0 %	0.353
eye morphology	vitreous	females	4.0 %	1.00
eye morphology	vitreous	males	13.0 %	0.126
eye morphology	vitreous	both	5.0 %	0.355
SHIRPA	activity body position	females	1.0 %	1.0
SHIRPA	activity body position	males	2.0 %	1.0
SHIRPA	activity body position	both	1.0 %	1.00
SHIRPA	aggression	females	0.0 %	1.00
SHIRPA	aggression	males	1.0 %	1.0
SHIRPA	aggression	both	1.0 %	1.00
SHIRPA	body length	females	0.0 %	1.00
SHIRPA	body length	males	0.0 %	1.00
SHIRPA	body length	both	0.0 %	1.0
SHIRPA	body position	females	0.0 %	1.00
SHIRPA	body position	males	1.0 %	1.0
SHIRPA	body position	both	0.0 %	1.0
SHIRPA	body thickness	females	1.0 %	1.0
SHIRPA	body thickness	males	0.0 %	1.00
SHIRPA	body thickness	both	0.0 %	1.0
SHIRPA	coat color abdomen	females	3.0 %	1.00
SHIRPA	coat color abdomen	males	4.0 %	1.0
SHIRPA	coat color abdomen	both	4.0 %	1.0
SHIRPA	coat color back	females	0.0 %	1.0
SHIRPA	coat color back	males	0.0 %	1.0
SHIRPA	coat color back	both	0.0 %	1.00
SHIRPA	coat color head	females	0.0 %	1.0
SHIRPA	coat color head	males	0.0 %	1.0
SHIRPA	coat color head	both	0.0 %	1.00
SHIRPA	coat color pattern abdomen	females	1.0 %	1.0
SHIRPA	coat color pattern abdomen	males	1.0 %	1.00
SHIRPA	coat color pattern abdomen	both	1.0 %	1.00
SHIRPA	coat color pattern back	females	0.0 %	1.00
SHIRPA	coat color pattern back	males	0.0 %	1.0
SHIRPA	coat color pattern back	both	0.0 %	1.00
SHIRPA	coat color pattern head	females	0.0 %	1.0
SHIRPA	coat color pattern head	males	0.0 %	1.0
SHIRPA	coat color pattern head	both	0.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	females	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	males	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	both	2.0 %	1.0
SHIRPA	coat hair back texture appearance	females	0.0 %	1.0
SHIRPA	coat hair back texture appearance	males	0.0 %	1.0
SHIRPA	coat hair back texture appearance	both	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	females	0.0 %	1.00
SHIRPA	coat hair distribution abdomen	males	1.0 %	1.0
SHIRPA	coat hair distribution abdomen	both	1.0 %	1.00
SHIRPA	coat hair distribution back	females	0.0 %	1.00
SHIRPA	coat hair distribution back	males	66.0 %	0.0000231
SHIRPA	coat hair distribution back	both	25.0 %	0.000148
SHIRPA	coat hair distribution head	females	1.0 %	1.00
SHIRPA	coat hair distribution head	males	1.0 %	1.0
SHIRPA	coat hair distribution head	both	1.0 %	1.0
SHIRPA	coat hair head texture appearance	females	0.0 %	1.0
SHIRPA	coat hair head texture appearance	males	0.0 %	1.0
SHIRPA	coat hair head texture appearance	both	0.0 %	1.0
SHIRPA	contact righting	females	5.0 %	1.0
SHIRPA	contact righting	males	5.0 %	1.00
SHIRPA	contact righting	both	5.0 %	1.00
SHIRPA	ear morphology	females	0.0 %	1.0
SHIRPA	ear morphology	males	0.0 %	1.0
SHIRPA	ear morphology	both	0.0 %	1.0
SHIRPA	fat distribution	females	0.0 %	1.0
SHIRPA	fat distribution	males	0.0 %	1.0
SHIRPA	fat distribution	both	0.0 %	1.0
SHIRPA	forelimb digit number	females	0.0 %	1.0
SHIRPA	forelimb digit number	males	0.0 %	1.0
SHIRPA	forelimb digit number	both	0.0 %	1.00
SHIRPA	forelimb digit position	females	0.0 %	1.0
SHIRPA	forelimb digit position	males	0.0 %	1.0
SHIRPA	forelimb digit position	both	0.0 %	1.0
SHIRPA	forelimb digit shape	females	0.0 %	1.0
SHIRPA	forelimb digit shape	males	0.0 %	1.0
SHIRPA	forelimb digit shape	both	0.0 %	1.0
SHIRPA	forelimb digit size	females	0.0 %	1.0
SHIRPA	forelimb digit size	males	0.0 %	1.0
SHIRPA	forelimb digit size	both	0.0 %	1.0
SHIRPA	forelimb footpads	females	0.0 %	1.0
SHIRPA	forelimb footpads	males	0.0 %	1.0
SHIRPA	forelimb footpads	both	0.0 %	1.0
SHIRPA	forelimb nail length	females	0.0 %	1.0
SHIRPA	forelimb nail length	males	0.0 %	1.0
SHIRPA	forelimb nail length	both	0.0 %	1.0
SHIRPA	forelimb nail number	females	0.0 %	1.0
SHIRPA	forelimb nail number	males	0.0 %	1.0
SHIRPA	forelimb nail number	both	0.0 %	1.0
SHIRPA	forelimb nail position	females	0.0 %	1.0
SHIRPA	forelimb nail position	males	0.0 %	1.0
SHIRPA	forelimb nail position	both	0.0 %	1.0
SHIRPA	forelimb nail shape	females	0.0 %	1.0
SHIRPA	forelimb nail shape	males	0.0 %	1.0
SHIRPA	forelimb nail shape	both	0.0 %	1.0
SHIRPA	forelimbs position	females	0.0 %	1.0
SHIRPA	forelimbs position	males	0.0 %	1.0
SHIRPA	forelimbs position	both	0.0 %	1.0
SHIRPA	forelimbs shape	females	0.0 %	1.0
SHIRPA	forelimbs shape	males	0.0 %	1.0
SHIRPA	forelimbs shape	both	0.0 %	1.0
SHIRPA	forelimbs size	females	0.0 %	1.00
SHIRPA	forelimbs size	males	0.0 %	1.0
SHIRPA	forelimbs size	both	0.0 %	1.0
SHIRPA	forepaw position	females	0.0 %	1.0
SHIRPA	forepaw position	males	0.0 %	1.0
SHIRPA	forepaw position	both	0.0 %	1.0
SHIRPA	forepaw shape	females	0.0 %	1.0
SHIRPA	forepaw shape	males	0.0 %	1.0
SHIRPA	forepaw shape	both	0.0 %	1.0
SHIRPA	forepaw size	females	0.0 %	1.0
SHIRPA	forepaw size	males	0.0 %	1.0
SHIRPA	forepaw size	both	0.0 %	1.0
SHIRPA	gait (fluidity)	females	0.0 %	1.0
SHIRPA	gait (fluidity)	males	0.0 %	1.00
SHIRPA	gait (fluidity)	both	0.0 %	1.0
SHIRPA	genitalia morphology	females	0.0 %	1.0
SHIRPA	genitalia morphology	males	0.0 %	1.0
SHIRPA	genitalia morphology	both	0.0 %	1.00
SHIRPA	genitalia presence	females	0.0 %	1.0
SHIRPA	genitalia presence	males	0.0 %	1.0
SHIRPA	genitalia presence	both	0.0 %	1.0
SHIRPA	genitalia size	females	0.0 %	1.0
SHIRPA	genitalia size	males	0.0 %	1.0
SHIRPA	genitalia size	both	0.0 %	1.00
SHIRPA	head bobbing	females	0.0 %	1.0
SHIRPA	head bobbing	males	0.0 %	1.0
SHIRPA	head bobbing	both	0.0 %	1.0
SHIRPA	head morphology	females	0.0 %	1.0
SHIRPA	head morphology	males	0.0 %	1.0
SHIRPA	head morphology	both	0.0 %	1.0
SHIRPA	head size	females	0.0 %	1.0
SHIRPA	head size	males	0.0 %	1.00
SHIRPA	head size	both	0.0 %	1.00
SHIRPA	hindlimb digit number	females	1.0 %	1.0
SHIRPA	hindlimb digit number	males	0.0 %	1.0
SHIRPA	hindlimb digit number	both	0.0 %	1.00
SHIRPA	hindlimb digit position	females	0.0 %	1.0
SHIRPA	hindlimb digit position	males	0.0 %	1.0
SHIRPA	hindlimb digit position	both	0.0 %	1.0
SHIRPA	hindlimb digit shape	females	0.0 %	1.00
SHIRPA	hindlimb digit shape	males	0.0 %	1.0
SHIRPA	hindlimb digit shape	both	0.0 %	1.00
SHIRPA	hindlimb digit size	females	0.0 %	1.0
SHIRPA	hindlimb digit size	males	0.0 %	1.00
SHIRPA	hindlimb digit size	both	0.0 %	1.00
SHIRPA	hindlimb nail length	females	0.0 %	1.0
SHIRPA	hindlimb nail length	males	0.0 %	1.00
SHIRPA	hindlimb nail length	both	0.0 %	1.00
SHIRPA	hindlimb nail number	females	0.0 %	1.0
SHIRPA	hindlimb nail number	males	1.0 %	1.00
SHIRPA	hindlimb nail number	both	0.0 %	1.00
SHIRPA	hindlimb nail position	females	0.0 %	1.0
SHIRPA	hindlimb nail position	males	0.0 %	1.0
SHIRPA	hindlimb nail position	both	0.0 %	1.0
SHIRPA	hindlimb nail shape	females	0.0 %	1.0
SHIRPA	hindlimb nail shape	males	0.0 %	1.0
SHIRPA	hindlimb nail shape	both	0.0 %	1.0
SHIRPA	hindlimbs footpads	females	0.0 %	1.0
SHIRPA	hindlimbs footpads	males	0.0 %	1.0
SHIRPA	hindlimbs footpads	both	0.0 %	1.0
SHIRPA	hindlimbs position	females	0.0 %	1.0
SHIRPA	hindlimbs position	males	0.0 %	1.0
SHIRPA	hindlimbs position	both	0.0 %	1.0
SHIRPA	hindlimbs shape	females	0.0 %	1.0
SHIRPA	hindlimbs shape	males	0.0 %	1.0
SHIRPA	hindlimbs shape	both	0.0 %	1.0
SHIRPA	hindlimbs size	females	0.0 %	1.0
SHIRPA	hindlimbs size	males	0.0 %	1.0
SHIRPA	hindlimbs size	both	0.0 %	1.0
SHIRPA	hindpaw position	females	0.0 %	1.0
SHIRPA	hindpaw position	males	0.0 %	1.0
SHIRPA	hindpaw position	both	0.0 %	1.0
SHIRPA	hindpaw shape	females	0.0 %	1.0
SHIRPA	hindpaw shape	males	0.0 %	1.0
SHIRPA	hindpaw shape	both	0.0 %	1.0
SHIRPA	hindpaw size	females	0.0 %	1.0
SHIRPA	hindpaw size	males	0.0 %	1.0
SHIRPA	hindpaw size	both	0.0 %	1.0
SHIRPA	limb grasp	females	11.0 %	0.371
SHIRPA	limb grasp	males	28.0 %	0.162
SHIRPA	limb grasp	both	18.0 %	0.111
SHIRPA	lower lip morphology	females	0.0 %	1.0
SHIRPA	lower lip morphology	males	0.0 %	1.0
SHIRPA	lower lip morphology	both	0.0 %	1.0
SHIRPA	lower teeth appearance	females	0.0 %	1.0
SHIRPA	lower teeth appearance	males	0.0 %	1.0
SHIRPA	lower teeth appearance	both	0.0 %	1.0
SHIRPA	mouth morphology	females	0.0 %	1.0
SHIRPA	mouth morphology	males	0.0 %	1.00
SHIRPA	mouth morphology	both	0.0 %	1.0
SHIRPA	salivation	females	0.0 %	1.0
SHIRPA	salivation	males	0.0 %	1.0
SHIRPA	salivation	both	0.0 %	1.0
SHIRPA	skin color back paws	females	0.0 %	1.0
SHIRPA	skin color back paws	males	0.0 %	1.0
SHIRPA	skin color back paws	both	0.0 %	1.0
SHIRPA	skin color ear	females	0.0 %	1.0
SHIRPA	skin color ear	males	0.0 %	1.0
SHIRPA	skin color ear	both	0.0 %	1.0
SHIRPA	skin color front paws	females	0.0 %	1.0
SHIRPA	skin color front paws	males	0.0 %	1.0
SHIRPA	skin color front paws	both	0.0 %	1.0
SHIRPA	skin color snout	females	0.0 %	1.0
SHIRPA	skin color snout	males	0.0 %	1.0
SHIRPA	skin color snout	both	0.0 %	1.0
SHIRPA	skin color tail	females	0.0 %	1.0
SHIRPA	skin color tail	males	0.0 %	1.0
SHIRPA	skin color tail	both	0.0 %	1.0
SHIRPA	skin color whole body	females	0.0 %	1.0
SHIRPA	skin color whole body	males	0.0 %	1.0
SHIRPA	skin color whole body	both	0.0 %	1.0
SHIRPA	skin texture back paw	females	0.0 %	1.0
SHIRPA	skin texture back paw	males	0.0 %	1.0
SHIRPA	skin texture back paw	both	0.0 %	1.0
SHIRPA	skin texture ear	females	0.0 %	1.0
SHIRPA	skin texture ear	males	0.0 %	1.0
SHIRPA	skin texture ear	both	0.0 %	1.0
SHIRPA	skin texture front paws	females	0.0 %	1.0
SHIRPA	skin texture front paws	males	0.0 %	1.0
SHIRPA	skin texture front paws	both	0.0 %	1.0
SHIRPA	skin texture snout	females	0.0 %	1.0
SHIRPA	skin texture snout	males	0.0 %	1.0
SHIRPA	skin texture snout	both	0.0 %	1.0
SHIRPA	skin texture tail	females	0.0 %	1.0
SHIRPA	skin texture tail	males	0.0 %	1.0
SHIRPA	skin texture tail	both	0.0 %	1.0
SHIRPA	skin texture whole body	females	0.0 %	1.0
SHIRPA	skin texture whole body	males	0.0 %	1.0
SHIRPA	skin texture whole body	both	0.0 %	1.00
SHIRPA	snout size	females	0.0 %	1.00
SHIRPA	snout size	males	1.0 %	1.0
SHIRPA	snout size	both	0.0 %	1.0
SHIRPA	startle response	females	0.0 %	1.00
SHIRPA	startle response	males	0.0 %	1.00
SHIRPA	startle response	both	0.0 %	1.00
SHIRPA	tail curvature	females	0.0 %	1.0
SHIRPA	tail curvature	males	0.0 %	1.0
SHIRPA	tail curvature	both	0.0 %	1.0
SHIRPA	tail elevation	females	1.0 %	1.0
SHIRPA	tail elevation	males	2.0 %	1.0
SHIRPA	tail elevation	both	1.0 %	1.0
SHIRPA	tail length	females	0.0 %	1.0
SHIRPA	tail length	males	0.0 %	1.0
SHIRPA	tail length	both	0.0 %	1.0
SHIRPA	tail morphology	females	0.0 %	1.00
SHIRPA	tail morphology	males	0.0 %	1.0
SHIRPA	tail morphology	both	0.0 %	1.00
SHIRPA	tail presence	females	0.0 %	1.0
SHIRPA	tail presence	males	0.0 %	1.0
SHIRPA	tail presence	both	0.0 %	1.0
SHIRPA	tail shape	females	0.0 %	1.0
SHIRPA	tail shape	males	0.0 %	1.0
SHIRPA	tail shape	both	0.0 %	1.0
SHIRPA	tail thickness	females	0.0 %	1.0
SHIRPA	tail thickness	males	0.0 %	1.0
SHIRPA	tail thickness	both	0.0 %	1.0
SHIRPA	teeth presence	females	0.0 %	1.0
SHIRPA	teeth presence	males	0.0 %	1.00
SHIRPA	teeth presence	both	0.0 %	1.0
SHIRPA	transfer arousal	females	1.0 %	1.0
SHIRPA	transfer arousal	males	2.0 %	1.0
SHIRPA	transfer arousal	both	1.0 %	1.0
SHIRPA	tremor	females	0.0 %	1.00
SHIRPA	tremor	males	0.0 %	1.00
SHIRPA	tremor	both	0.0 %	1.0
SHIRPA	trunk curl	females	0.0 %	1.00
SHIRPA	trunk curl	males	0.0 %	1.0
SHIRPA	trunk curl	both	0.0 %	1.00
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	females	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	males	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	both	0.0 %	1.00
SHIRPA	upper lip morphology	females	0.0 %	1.0
SHIRPA	upper lip morphology	males	0.0 %	1.0
SHIRPA	upper lip morphology	both	0.0 %	1.0
SHIRPA	upper teeth appearance	females	0.0 %	1.0
SHIRPA	upper teeth appearance	males	0.0 %	1.0
SHIRPA	upper teeth appearance	both	0.0 %	1.0
SHIRPA	vibrissae appearance	females	2.0 %	1.0
SHIRPA	vibrissae appearance	males	1.0 %	1.0
SHIRPA	vibrissae appearance	both	1.0 %	1.0
SHIRPA	vibrissae presence	females	2.0 %	1.0
SHIRPA	vibrissae presence	males	1.0 %	1.0
SHIRPA	vibrissae presence	both	2.0 %	1.0
SHIRPA	vocalization	females	2.0 %	1.0
SHIRPA	vocalization	males	2.0 %	1.0
SHIRPA	vocalization	both	2.0 %	1.0

GENOTYPE CORRELATION PLOT

Correlate C530008M17Rik^em1(IMPC)J/Mmjax -/- with genotype: