MPD: JaxKOMP-EAP genotype: Thap1<sup>em1(IMPC)J</sup>/Mmjax -/+

JaxKOMP-EAP effect sizes: Thap1^em1(IMPC)J/Mmjax -/+ Gene Thap1

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	0.34171	2.1547	-0.18839	0.966	0.876
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	1.7054	3.1822	0.40855	0.885	0.600
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	-1.4753	2.1739	-0.50898	0.806	0.507
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	-1.8730	2.5604	-0.41023	0.780	0.476
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	-8.3122	2.6178	-1.1710	0.110	0.00588
body composition	body length	-0.030041	0.063371	-0.16070	0.831	0.640
body composition	body weight (at time of DXA)	0.97550	0.94004	0.89616	0.532	0.311
body composition	bone area, whole body scan, head excluded	-0.25328	0.18581	-0.81317	0.451	0.187
body composition	bone mineral content of whole body scan, head excluded	-0.016613	0.017578	-0.76471	0.640	0.355
body composition	bone mineral content to body weight ratio	-0.00069431	0.00054499	-0.71975	0.477	0.217
body composition	bone mineral density of whole body scan, head excluded	-0.00096875	0.0010423	-0.99580	0.659	0.363
body composition	fat tissue mass of whole body scan, head excluded	0.56382	0.46892	0.84201	0.485	0.243
body composition	fat tissue mass to body weight ratio	0.017692	0.016607	0.81888	0.542	0.299
body composition	lean tissue mass of whole body scan, head excluded	-0.10318	0.60734	-0.37739	0.947	0.867
body composition	lean tissue mass to body weight ratio	0.0018721	0.015849	0.040308	0.953	0.907
body composition	percent fat, whole body scan, head excluded	1.4066	1.6257	0.72863	0.639	0.397
body composition	ratio of soft-tissue attenuation coefficients	-0.0015627	0.0018073	-0.73949	0.638	0.397
body composition	tissue area	-0.032326	0.24629	0.073872	0.967	0.897
body composition	total tissue mass, whole body scan, head excluded	0.46064	0.41429	0.75197	0.529	0.279
clinical blood chemistry	alanine transaminase (plasma ALT)	-7.6667	3.2765	-0.66961	0.296	0.0279
clinical blood chemistry	albumin (plasma Alb)	0.17022	0.57919	0.29808	0.921	0.771
clinical blood chemistry	alkaline phosphatase (plasma ALP)	-5.4872	4.7173	-1.4225	0.507	0.256
clinical blood chemistry	aspartate transaminase (plasma AST)	-47.384	8.9795	-1.7554	0.00198	0.0000235
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	-1.0799	0.32145	-2.2606	0.0991	0.00271
clinical blood chemistry	blood urea nitrogen (BUN)	2.1667	0.92248	0.84735	0.147	0.0274
clinical blood chemistry	calcium (plasma Ca)	0.29387	0.11895	2.0687	0.112	0.0210
clinical blood chemistry	creatinine (plasma)	-0.10144	0.038539	-1.7237	0.0993	0.0149
clinical blood chemistry	glucose (plasma GLU, no fast)	-14.639	17.517	-0.28445	0.618	0.412
clinical blood chemistry	HDL cholesterol (plasma HDL)	2.9987	1.8702	0.39932	0.386	0.122
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	0.029466	0.0095721	1.4123	0.0859	0.00515
clinical blood chemistry	phosphorus (plasma phosphate)	-0.29687	0.24931	-0.52882	0.535	0.246
clinical blood chemistry	total bilirubin (plasma TBIL)	-0.0079776	0.0082298	-0.61079	0.689	0.342
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	0.96682	2.8284	-0.061888	0.902	0.736
clinical blood chemistry	total protein (plasma TP)	-0.59003	0.54868	-0.51427	0.571	0.293
clinical blood chemistry	triglyceride (plasma TG, no fast)	20.234	10.811	1.2018	0.286	0.0740
EKG	duration of PQ interval	-0.54791	0.68816	-0.44997	0.886	0.436
EKG	duration of PR interval	-1.2070	0.80643	-1.0420	0.711	0.152
EKG	duration of QRS interval	-0.48747	0.43332	-1.5069	0.885	0.275
EKG	duration of QT interval	-1.6122	1.0312	-1.2697	0.644	0.135
EKG	duration of QTC interval, calculated by dividing QT interval by square root of preceding RR interval	-1.2497	1.0110	-1.2388	0.790	0.233
EKG	duration of RR interval	-3.6624	2.0709	-1.5659	0.479	0.0949
EKG	duration of ST interval	-1.4133	0.86853	-1.1484	0.632	0.122
EKG	heart rate coefficient of variation (signal intensity)	-1.2571	1.2110	-0.97496	0.863	0.313
EKG	heart rate variability, mean of differences between sequential beats; beats per min	-7.9027	8.2640	-0.87305	0.853	0.352
EKG	heart rate, beats per min	29.401	16.581	1.4581	0.460	0.0941
EKG	mean R amplitude, mean amplitude of signal measured from isoelectric line to peak of QRS	0.23433	0.10774	1.6539	0.299	0.0432
EKG	mean SR amplitude, mean amplitude of signal measured from signal minimum line to peak of QRS	0.39218	0.13138	2.0194	0.162	0.00794
EKG	number of signals	-1.2819	3.3888	-0.30700	0.941	0.710
EKG	proportion of number pairs of successive beat-to-beat intervals that exceed 50 ms	-6.4523	6.6212	-1.1623	0.846	0.343
EKG	QT dispersion, measured as inter-lead variability of QT intervals	-2.4150	4.6267	-0.70517	0.964	0.608
EKG	QTc dispersion, calculated as rate-corrected QT dispersion	-3.0987	4.8207	-0.83532	0.931	0.528
EKG	root mean square of successive differences of neighboring RR intervals	-0.79976	1.8739	-0.29435	0.939	0.675
glucose tolerance test	amount glucose injected	3.7385	3.3930	1.3343	0.655	0.283
glucose tolerance test	plasma glucose, 0min	-8.2359	5.2980	-0.97035	0.311	0.134
glucose tolerance test	plasma glucose, 15min	-32.575	23.075	-0.77538	0.482	0.172
glucose tolerance test	plasma glucose, 30min	-15.313	22.754	-0.35460	0.774	0.508
glucose tolerance test	plasma glucose, 60min	13.062	24.188	0.63957	0.830	0.595
glucose tolerance test	plasma glucose, 120min	10.425	8.2389	0.60294	0.528	0.219
grip strength	body weight (at time of grip strength test)	0.081852	0.53580	0.28675	0.937	0.880
grip strength	forelimb and hindlimb grip strength (mean of trials), average	26.836	8.3539	2.0600	0.0273	0.00349
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	1.2236	0.34570	1.8150	0.0164	0.00153
grip strength	forelimb and hindlimb grip strength by trial, trial1	11.897	10.995	1.0462	0.592	0.289
grip strength	forelimb and hindlimb grip strength by trial, trial2	31.522	12.443	2.0480	0.112	0.0179
grip strength	forelimb and hindlimb grip strength by trial, trial3	36.110	10.808	2.3547	0.0355	0.00253
grip strength	forelimb grip strength (mean of trials), average	19.541	6.5532	2.4597	0.0567	0.00615
grip strength	forelimb grip strength (mean of trials), average normalized to bw	0.88486	0.29027	2.1534	0.0555	0.00523
grip strength	forelimb grip strength by trial, trial1	26.391	6.7796	2.8314	0.0305	0.000618
grip strength	forelimb grip strength by trial, trial2	12.458	7.5565	1.5430	0.397	0.111
grip strength	forelimb grip strength by trial, trial3	17.345	9.4506	1.9050	0.329	0.0779
heart weight	heart weight, normalized to body weight	-0.21873	0.14104	-1.2893	0.320	0.137
heart weight	heart weight, weight	-6.1074	4.7975	-1.2210	0.425	0.218
hematology	basophil differential (percent of total WBC)	-0.033333	0.053787	-0.49439	0.843	0.541
hematology	calculated hemoglobin (cHGB)	0.050830	0.10925	-0.11848	0.834	0.646
hematology	eosinophil differential (percent of total WBC)	0.17917	0.21171	0.58485	0.774	0.406
hematology	hematocrit (HCT)	-0.32500	0.33133	-0.67021	0.614	0.336
hematology	hemoglobin concentration distribution width (HDW)	-0.057264	0.020192	-1.4755	0.108	0.00936
hematology	large unstained cells (percent of total WBC)	0.11667	0.044876	0.76859	0.190	0.0157
hematology	lymphocyte differential (percent of total WBC)	1.6167	0.74887	0.56916	0.199	0.0411
hematology	mean corpuscular hemoglobin (CHr)	0.083333	0.046830	0.69767	0.262	0.0878
hematology	mean platelet volume (MPV)	0.067905	0.073005	0.27152	0.595	0.362
hematology	mean RBC corpuscular hemoglobin (MCH)	0.60417	0.25853	1.6513	0.221	0.0281
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	1.4417	0.57746	1.8642	0.192	0.0198
hematology	mean RBC corpuscular volume (MCV)	-0.074673	0.36194	-0.13710	0.932	0.838
hematology	measured hemoglobin (mHGB)	0.52500	0.29868	1.1323	0.350	0.0915
hematology	monocyte differential (percent of total WBC)	-0.17917	0.079839	-0.38223	0.277	0.0343
hematology	neutrophil differential (percent of total WBC)	-1.6875	0.68221	-0.74212	0.137	0.0208
hematology	platelet count (PLT; units per volume x 10³)	117.94	50.969	1.4938	0.257	0.0300
hematology	RBC corpuscular distribution width (RDW)	-0.087500	0.14149	-0.32134	0.750	0.542
hematology	RBC corpuscular hemoglobin concentration mean (CHCM)	0.012132	0.27614	0.0087037	0.982	0.965
hematology	red blood cell count (RBC; per volume x 10⁶)	-0.010000	0.081284	-0.39300	0.954	0.903
hematology	reticulocyte count (Retic; units per volume x 10⁹)	6.3437	29.247	0.37314	0.949	0.830
hematology	reticulocyte differential (percent of total RBC)	0.066828	0.30065	0.50475	0.932	0.826
hematology	white blood cell count (WBC; units per volume x 10³)	2.7246	0.34340	1.8423	0.00000755	4.94e-8
holeboard	number of hole pokes by individual hole number, 20 min test, 1	-0.91831	0.88472	-0.86592	0.739	0.309
holeboard	number of hole pokes by individual hole number, 20 min test, 2	-1.4394	1.0310	-1.9500	0.700	0.175
holeboard	number of hole pokes by individual hole number, 20 min test, 3	-0.47606	0.73620	-0.72242	0.891	0.524
holeboard	number of hole pokes by individual hole number, 20 min test, 4	-1.5705	0.89722	-1.5169	0.553	0.0923
holeboard	number of hole pokes by individual hole number, 20 min test, 5	-0.94208	0.67944	-1.4179	0.683	0.178
holeboard	number of hole pokes by individual hole number, 20 min test, 6	-0.12817	0.35465	-0.33867	0.957	0.721
holeboard	number of hole pokes by individual hole number, 20 min test, 7	-0.10423	0.45313	-0.30821	0.983	0.820
holeboard	number of hole pokes by individual hole number, 20 min test, 8	-0.68028	0.46251	-1.0157	0.701	0.154
holeboard	number of hole pokes by individual hole number, 20 min test, 9	-0.30141	0.39972	-0.47124	0.863	0.458
holeboard	number of hole pokes by individual hole number, 20 min test, 10	-0.61268	0.46334	-1.6455	0.748	0.198
holeboard	number of hole pokes by individual hole number, 20 min test, 11	-0.56338	0.71263	-1.4853	0.861	0.437
holeboard	number of hole pokes by individual hole number, 20 min test, 12	-0.15634	0.73925	-0.17463	0.960	0.834
holeboard	number of hole pokes by individual hole number, 20 min test, 13	-0.016815	0.86099	0.059073	0.999	0.985
holeboard	number of hole pokes by individual hole number, 20 min test, 14	-0.81127	0.51060	-1.2069	0.563	0.125
holeboard	number of hole pokes by individual hole number, 20 min test, 15	0.17465	0.61905	0.32619	0.915	0.780
holeboard	number of hole pokes by individual hole number, 20 min test, 16	0.35211	0.74005	0.37281	0.903	0.638
holeboard	total number of hole pokes, 20 min test	-8.2153	5.0175	-1.0988	0.368	0.114
light / dark	fecal boli count, 20 min test	0.26203	0.95720	0.31757	0.929	0.787
light / dark	latency to enter dark zone, 20 min test	66.564	48.198	1.0817	0.612	0.182
light / dark	number of transitions between light and dark zones, 20 min test	-16.952	7.9200	-1.5837	0.255	0.0437
light / dark	percentage of total time in dark zone, 20 min test	6.4577	4.7634	1.3206	0.567	0.189
light / dark	percentage of total time in light zone, 20 min test	-6.4577	4.7634	-1.3271	0.568	0.189
light / dark	time mobile in dark zone, 20 min test	-10.156	13.820	-0.75389	0.742	0.470
light / dark	time mobile in light zone, 20 min test	-9.2771	13.623	-0.90253	0.741	0.503
light / dark	time spent in dark zone, 20 min test	19.570	59.285	0.50158	0.924	0.744
light / dark	time spent in light zone, 20 min test	-19.570	59.285	-0.50158	0.924	0.744
open field	average speed in center of arena, 20 min test	0.62573	0.45483	0.97856	0.514	0.179
open field	average speed in periphery of arena, 20 min test	0.0014342	0.14392	-0.52918	0.995	0.992
open field	distance traveled habituation ratio, 20 min test	-14.575	8.0039	-1.2163	0.344	0.0790
open field	distance traveled in center of arena, 20 min test	-54.702	95.136	-0.71855	0.760	0.570
open field	distance traveled in periphery of arena, 20 min test	54.272	134.13	-0.20894	0.835	0.689
open field	distance traveled slope, 20 min test	-11.062	7.6276	-0.95711	0.472	0.158
open field	distance traveled, 20 min test, 1st 5min	28.886	70.224	-0.097492	0.849	0.684
open field	distance traveled, 20 min test, 2nd 5min	-26.477	46.782	-0.80099	0.776	0.576
open field	distance traveled, 20 min test, 3rd 5min	38.167	54.070	-0.0033565	0.714	0.486
open field	distance traveled, 20 min test, 4th 5min	-55.704	56.724	-1.1081	0.582	0.334
open field	number of clockwise revolution episodes, 20 min test	1.2764	1.3173	0.34525	0.696	0.340
open field	number of counter-clockwise revolution episodes, 20 min test	-0.31972	1.2903	-0.59363	0.913	0.806
open field	number of fecal boli, 20 min test	-0.53220	0.93842	-0.13535	0.802	0.575
open field	number of rears in 5 min bins, 20 min test, 1st 5min	-2.4610	2.1529	-0.87108	0.529	0.262
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	-1.7934	2.4226	-0.81214	0.716	0.465
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	-0.56887	2.5722	-0.43564	0.920	0.826
open field	number of rears in 5 min bins, 20 min test, 4th 5min	-3.0660	3.1456	-0.98945	0.610	0.337
open field	percentage of total time in center of arena, 20 min test	-2.9805	2.4767	-0.92574	0.556	0.238
open field	percentage of total time in center of arena, slope, 20 min test	-0.40232	1.2514	-0.10424	0.946	0.750
open field	percentage of total time in center, habituation ratio, 20 min test	-0.25931	1.2751	-0.015440	0.960	0.840
open field	percentage of total time in corners of arena, 20 min test	6.3881	3.7785	1.4359	0.389	0.101
open field	percentage of total time in corners, habituation ratio, 20 min test	2.3991	1.8910	0.78262	0.709	0.215
open field	percentage of total time in corners, slope, 20 min test	2.3953	1.9548	0.81588	0.717	0.230
open field	permanence time in center of arena, 20 min test	-35.764	29.719	-0.92574	0.556	0.238
open field	permanence time in corners of arena, 20 min test	76.649	45.343	1.4359	0.389	0.101
open field	permanence time in periphery of arena, 20 min test	35.841	29.718	0.92574	0.555	0.237
open field	total distance traveled, 20 min test	18.781	186.57	-0.44008	0.960	0.921
open field	total number of rears, 20 min test	-6.5124	8.4656	-0.80284	0.685	0.448
open field	whole arena average speed, 20 min test	0.015372	0.15591	-0.44304	0.961	0.922
open field	whole arena resting time, 20 min test	-11.333	17.444	0.22131	0.703	0.521
open field	whole arena time spent mobile, 20 min test	11.372	17.455	-0.018126	0.705	0.520
open field	whole arena time spent vertical, 20 min test	-7.7457	8.8115	-0.73605	0.684	0.386
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	-1.6095	2.1109	-0.47646	0.727	0.453

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Sex	Trait Effect	P-value
eye morphology	anterior chamber depth	females	1.0 %	1.0
eye morphology	anterior chamber depth	males	0.0 %	1.0
eye morphology	anterior chamber depth	both	1.0 %	1.0
eye morphology	bulging eye	females	1.0 %	1.0
eye morphology	bulging eye	males	0.0 %	1.0
eye morphology	bulging eye	both	1.0 %	1.00
eye morphology	cornea	females	12.0 %	0.175
eye morphology	cornea	males	36.0 %	0.0000462
eye morphology	cornea	both	22.0 %	0.000159
eye morphology	cornea opacity	females	5.0 %	1.00
eye morphology	cornea opacity	males	1.0 %	1.0
eye morphology	cornea opacity	both	3.0 %	1.00
eye morphology	cornea vascularization	females	3.0 %	1.0
eye morphology	cornea vascularization	males	1.0 %	1.0
eye morphology	cornea vascularization	both	2.0 %	1.00
eye morphology	corneal deposits	females	2.0 %	1.0
eye morphology	corneal deposits	males	1.0 %	1.0
eye morphology	corneal deposits	both	1.0 %	1.00
eye morphology	corneal mineralization	females	2.0 %	1.0
eye morphology	corneal mineralization	males	1.0 %	1.0
eye morphology	corneal mineralization	both	1.0 %	1.00
eye morphology	corneal scleralization	females	12.0 %	0.146
eye morphology	corneal scleralization	males	1.0 %	1.0
eye morphology	corneal scleralization	both	6.0 %	0.141
eye morphology	corneal ulcer	females	1.0 %	1.0
eye morphology	corneal ulcer	males	1.0 %	1.0
eye morphology	corneal ulcer	both	1.0 %	1.00
eye morphology	eye closure	females	1.0 %	1.00
eye morphology	eye closure	males	0.0 %	1.0
eye morphology	eye closure	both	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	females	2.0 %	1.00
eye morphology	eye hemorrhage or blood presence	males	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	both	1.0 %	1.00
eye morphology	eyelid morphology	females	1.0 %	1.0
eye morphology	eyelid morphology	males	0.0 %	1.0
eye morphology	eyelid morphology	both	1.0 %	1.0
eye morphology	eyes (present, absent)	females	1.0 %	1.0
eye morphology	eyes (present, absent)	males	0.0 %	1.0
eye morphology	eyes (present, absent)	both	0.0 %	1.0
eye morphology	fusion between cornea and lens	females	4.0 %	1.00
eye morphology	fusion between cornea and lens	males	2.0 %	1.0
eye morphology	fusion between cornea and lens	both	3.0 %	1.00
eye morphology	iris pigmentation	females	2.0 %	1.0
eye morphology	iris pigmentation	males	1.0 %	1.0
eye morphology	iris pigmentation	both	2.0 %	1.00
eye morphology	iris transillumination	females	2.0 %	1.00
eye morphology	iris transillumination	males	1.0 %	1.0
eye morphology	iris transillumination	both	1.0 %	1.00
eye morphology	irispupil	females	11.0 %	0.275
eye morphology	irispupil	males	3.0 %	1.0
eye morphology	irispupil	both	5.0 %	0.435
eye morphology	lacrimation	females	3.0 %	1.0
eye morphology	lacrimation	males	2.0 %	1.0
eye morphology	lacrimation	both	3.0 %	1.0
eye morphology	lens	females	10.0 %	1.00
eye morphology	lens	males	8.0 %	1.0
eye morphology	lens	both	9.0 %	1.0
eye morphology	lens opacity	females	12.0 %	0.197
eye morphology	lens opacity	males	6.0 %	1.0
eye morphology	lens opacity	both	6.0 %	0.257
eye morphology	narrow eye opening	females	2.0 %	1.0
eye morphology	narrow eye opening	males	1.0 %	1.0
eye morphology	narrow eye opening	both	1.0 %	1.0
eye morphology	optic disc	females	4.0 %	1.00
eye morphology	optic disc	males	2.0 %	1.0
eye morphology	optic disc	both	3.0 %	1.00
eye morphology	persistence of hyaloid vascular system	females	31.0 %	0.145
eye morphology	persistence of hyaloid vascular system	males	5.0 %	1.0
eye morphology	persistence of hyaloid vascular system	both	14.0 %	0.232
eye morphology	pupil dilation	females	2.0 %	1.0
eye morphology	pupil dilation	males	1.0 %	1.0
eye morphology	pupil dilation	both	2.0 %	1.0
eye morphology	pupil light response	females	2.0 %	1.00
eye morphology	pupil light response	males	1.0 %	1.0
eye morphology	pupil light response	both	2.0 %	1.00
eye morphology	pupil position	females	11.0 %	0.301
eye morphology	pupil position	males	3.0 %	1.0
eye morphology	pupil position	both	5.0 %	0.461
eye morphology	pupil shape	females	3.0 %	1.00
eye morphology	pupil shape	males	2.0 %	1.0
eye morphology	pupil shape	both	3.0 %	1.00
eye morphology	retina	females	10.0 %	1.0
eye morphology	retina	males	16.0 %	1.0
eye morphology	retina	both	13.0 %	1.0
eye morphology	retinal blood vessels	females	4.0 %	1.0
eye morphology	retinal blood vessels	males	2.0 %	1.0
eye morphology	retinal blood vessels	both	3.0 %	1.0
eye morphology	retinal blood vessels pattern	females	5.0 %	1.0
eye morphology	retinal blood vessels pattern	males	25.0 %	0.00222
eye morphology	retinal blood vessels pattern	both	12.0 %	0.0156
eye morphology	retinal blood vessels structure	females	4.0 %	1.00
eye morphology	retinal blood vessels structure	males	2.0 %	1.0
eye morphology	retinal blood vessels structure	both	3.0 %	1.00
eye morphology	retinal pigmentation	females	12.0 %	1.0
eye morphology	retinal pigmentation	males	24.0 %	0.0749
eye morphology	retinal pigmentation	both	10.0 %	0.299
eye morphology	retinal structure	females	4.0 %	1.00
eye morphology	retinal structure	males	2.0 %	1.0
eye morphology	retinal structure	both	3.0 %	1.00
eye morphology	synechia	females	4.0 %	1.0
eye morphology	synechia	males	2.0 %	1.0
eye morphology	synechia	both	3.0 %	1.00
eye morphology	vitreous	females	4.0 %	1.00
eye morphology	vitreous	males	2.0 %	1.0
eye morphology	vitreous	both	3.0 %	1.00
SHIRPA	activity body position	females	1.0 %	1.0
SHIRPA	activity body position	males	2.0 %	1.0
SHIRPA	activity body position	both	1.0 %	1.00
SHIRPA	aggression	females	0.0 %	1.00
SHIRPA	aggression	males	1.0 %	1.0
SHIRPA	aggression	both	1.0 %	1.0
SHIRPA	body length	females	0.0 %	1.0
SHIRPA	body length	males	0.0 %	1.00
SHIRPA	body length	both	0.0 %	1.00
SHIRPA	body position	females	0.0 %	1.0
SHIRPA	body position	males	1.0 %	1.0
SHIRPA	body position	both	0.0 %	1.0
SHIRPA	body thickness	females	1.0 %	1.0
SHIRPA	body thickness	males	0.0 %	1.0
SHIRPA	body thickness	both	0.0 %	1.0
SHIRPA	coat color abdomen	females	3.0 %	1.00
SHIRPA	coat color abdomen	males	4.0 %	1.0
SHIRPA	coat color abdomen	both	4.0 %	1.0
SHIRPA	coat color back	females	0.0 %	1.0
SHIRPA	coat color back	males	0.0 %	1.00
SHIRPA	coat color back	both	0.0 %	1.00
SHIRPA	coat color head	females	0.0 %	1.0
SHIRPA	coat color head	males	0.0 %	1.00
SHIRPA	coat color head	both	0.0 %	1.0
SHIRPA	coat color pattern abdomen	females	1.0 %	1.0
SHIRPA	coat color pattern abdomen	males	1.0 %	1.0
SHIRPA	coat color pattern abdomen	both	1.0 %	1.0
SHIRPA	coat color pattern back	females	0.0 %	1.0
SHIRPA	coat color pattern back	males	0.0 %	1.00
SHIRPA	coat color pattern back	both	0.0 %	1.0
SHIRPA	coat color pattern head	females	0.0 %	1.0
SHIRPA	coat color pattern head	males	0.0 %	1.0
SHIRPA	coat color pattern head	both	0.0 %	1.00
SHIRPA	coat hair abdomen texture appearance	females	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	males	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	both	2.0 %	1.0
SHIRPA	coat hair back texture appearance	females	0.0 %	1.0
SHIRPA	coat hair back texture appearance	males	0.0 %	1.0
SHIRPA	coat hair back texture appearance	both	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	females	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	males	1.0 %	1.00
SHIRPA	coat hair distribution abdomen	both	1.0 %	1.00
SHIRPA	coat hair distribution back	females	0.0 %	1.0
SHIRPA	coat hair distribution back	males	0.0 %	1.0
SHIRPA	coat hair distribution back	both	0.0 %	1.0
SHIRPA	coat hair distribution head	females	1.0 %	1.00
SHIRPA	coat hair distribution head	males	1.0 %	1.0
SHIRPA	coat hair distribution head	both	1.0 %	1.0
SHIRPA	coat hair head texture appearance	females	0.0 %	1.00
SHIRPA	coat hair head texture appearance	males	0.0 %	1.0
SHIRPA	coat hair head texture appearance	both	0.0 %	1.0
SHIRPA	contact righting	females	5.0 %	1.0
SHIRPA	contact righting	males	5.0 %	1.00
SHIRPA	contact righting	both	5.0 %	1.00
SHIRPA	ear morphology	females	0.0 %	1.0
SHIRPA	ear morphology	males	0.0 %	1.0
SHIRPA	ear morphology	both	0.0 %	1.0
SHIRPA	fat distribution	females	0.0 %	1.0
SHIRPA	fat distribution	males	0.0 %	1.0
SHIRPA	fat distribution	both	0.0 %	1.00
SHIRPA	forelimb digit number	females	0.0 %	1.00
SHIRPA	forelimb digit number	males	0.0 %	1.0
SHIRPA	forelimb digit number	both	0.0 %	1.00
SHIRPA	forelimb digit position	females	0.0 %	1.0
SHIRPA	forelimb digit position	males	0.0 %	1.0
SHIRPA	forelimb digit position	both	0.0 %	1.0
SHIRPA	forelimb digit shape	females	0.0 %	1.0
SHIRPA	forelimb digit shape	males	0.0 %	1.0
SHIRPA	forelimb digit shape	both	0.0 %	1.0
SHIRPA	forelimb digit size	females	0.0 %	1.0
SHIRPA	forelimb digit size	males	0.0 %	1.0
SHIRPA	forelimb digit size	both	0.0 %	1.0
SHIRPA	forelimb footpads	females	0.0 %	1.0
SHIRPA	forelimb footpads	males	0.0 %	1.0
SHIRPA	forelimb footpads	both	0.0 %	1.0
SHIRPA	forelimb nail length	females	0.0 %	1.0
SHIRPA	forelimb nail length	males	0.0 %	1.0
SHIRPA	forelimb nail length	both	0.0 %	1.0
SHIRPA	forelimb nail number	females	0.0 %	1.0
SHIRPA	forelimb nail number	males	0.0 %	1.0
SHIRPA	forelimb nail number	both	0.0 %	1.0
SHIRPA	forelimb nail position	females	0.0 %	1.0
SHIRPA	forelimb nail position	males	0.0 %	1.0
SHIRPA	forelimb nail position	both	0.0 %	1.0
SHIRPA	forelimb nail shape	females	0.0 %	1.0
SHIRPA	forelimb nail shape	males	0.0 %	1.0
SHIRPA	forelimb nail shape	both	0.0 %	1.0
SHIRPA	forelimbs position	females	0.0 %	1.0
SHIRPA	forelimbs position	males	0.0 %	1.0
SHIRPA	forelimbs position	both	0.0 %	1.0
SHIRPA	forelimbs shape	females	0.0 %	1.0
SHIRPA	forelimbs shape	males	0.0 %	1.0
SHIRPA	forelimbs shape	both	0.0 %	1.0
SHIRPA	forelimbs size	females	0.0 %	1.0
SHIRPA	forelimbs size	males	0.0 %	1.0
SHIRPA	forelimbs size	both	0.0 %	1.0
SHIRPA	forepaw position	females	0.0 %	1.0
SHIRPA	forepaw position	males	0.0 %	1.0
SHIRPA	forepaw position	both	0.0 %	1.0
SHIRPA	forepaw shape	females	0.0 %	1.0
SHIRPA	forepaw shape	males	0.0 %	1.0
SHIRPA	forepaw shape	both	0.0 %	1.0
SHIRPA	forepaw size	females	0.0 %	1.0
SHIRPA	forepaw size	males	0.0 %	1.0
SHIRPA	forepaw size	both	0.0 %	1.0
SHIRPA	gait (fluidity)	females	0.0 %	1.0
SHIRPA	gait (fluidity)	males	0.0 %	1.00
SHIRPA	gait (fluidity)	both	0.0 %	1.00
SHIRPA	genitalia morphology	females	0.0 %	1.00
SHIRPA	genitalia morphology	males	0.0 %	1.0
SHIRPA	genitalia morphology	both	0.0 %	1.00
SHIRPA	genitalia presence	females	0.0 %	1.0
SHIRPA	genitalia presence	males	0.0 %	1.0
SHIRPA	genitalia presence	both	0.0 %	1.0
SHIRPA	genitalia size	females	0.0 %	1.0
SHIRPA	genitalia size	males	0.0 %	1.0
SHIRPA	genitalia size	both	0.0 %	1.0
SHIRPA	head bobbing	females	0.0 %	1.0
SHIRPA	head bobbing	males	0.0 %	1.0
SHIRPA	head bobbing	both	0.0 %	1.0
SHIRPA	head morphology	females	0.0 %	1.0
SHIRPA	head morphology	males	0.0 %	1.00
SHIRPA	head morphology	both	0.0 %	1.0
SHIRPA	head size	females	0.0 %	1.0
SHIRPA	head size	males	0.0 %	1.0
SHIRPA	head size	both	0.0 %	1.00
SHIRPA	hindlimb digit number	females	1.0 %	1.00
SHIRPA	hindlimb digit number	males	0.0 %	1.0
SHIRPA	hindlimb digit number	both	0.0 %	1.00
SHIRPA	hindlimb digit position	females	0.0 %	1.0
SHIRPA	hindlimb digit position	males	0.0 %	1.0
SHIRPA	hindlimb digit position	both	0.0 %	1.0
SHIRPA	hindlimb digit shape	females	0.0 %	1.0
SHIRPA	hindlimb digit shape	males	0.0 %	1.0
SHIRPA	hindlimb digit shape	both	0.0 %	1.0
SHIRPA	hindlimb digit size	females	0.0 %	1.00
SHIRPA	hindlimb digit size	males	0.0 %	1.0
SHIRPA	hindlimb digit size	both	0.0 %	1.00
SHIRPA	hindlimb nail length	females	0.0 %	1.0
SHIRPA	hindlimb nail length	males	0.0 %	1.0
SHIRPA	hindlimb nail length	both	0.0 %	1.00
SHIRPA	hindlimb nail number	females	0.0 %	1.0
SHIRPA	hindlimb nail number	males	1.0 %	1.0
SHIRPA	hindlimb nail number	both	0.0 %	1.00
SHIRPA	hindlimb nail position	females	0.0 %	1.0
SHIRPA	hindlimb nail position	males	0.0 %	1.0
SHIRPA	hindlimb nail position	both	0.0 %	1.0
SHIRPA	hindlimb nail shape	females	0.0 %	1.0
SHIRPA	hindlimb nail shape	males	0.0 %	1.0
SHIRPA	hindlimb nail shape	both	0.0 %	1.0
SHIRPA	hindlimbs footpads	females	0.0 %	1.0
SHIRPA	hindlimbs footpads	males	0.0 %	1.0
SHIRPA	hindlimbs footpads	both	0.0 %	1.0
SHIRPA	hindlimbs position	females	0.0 %	1.0
SHIRPA	hindlimbs position	males	0.0 %	1.0
SHIRPA	hindlimbs position	both	0.0 %	1.0
SHIRPA	hindlimbs shape	females	0.0 %	1.0
SHIRPA	hindlimbs shape	males	0.0 %	1.0
SHIRPA	hindlimbs shape	both	0.0 %	1.0
SHIRPA	hindlimbs size	females	0.0 %	1.0
SHIRPA	hindlimbs size	males	0.0 %	1.0
SHIRPA	hindlimbs size	both	0.0 %	1.0
SHIRPA	hindpaw position	females	0.0 %	1.0
SHIRPA	hindpaw position	males	0.0 %	1.0
SHIRPA	hindpaw position	both	0.0 %	1.0
SHIRPA	hindpaw shape	females	0.0 %	1.0
SHIRPA	hindpaw shape	males	0.0 %	1.0
SHIRPA	hindpaw shape	both	0.0 %	1.0
SHIRPA	hindpaw size	females	0.0 %	1.0
SHIRPA	hindpaw size	males	0.0 %	1.0
SHIRPA	hindpaw size	both	0.0 %	1.0
SHIRPA	limb grasp	females	16.0 %	0.154
SHIRPA	limb grasp	males	6.0 %	1.0
SHIRPA	limb grasp	both	5.0 %	0.327
SHIRPA	lower lip morphology	females	0.0 %	1.0
SHIRPA	lower lip morphology	males	0.0 %	1.0
SHIRPA	lower lip morphology	both	0.0 %	1.0
SHIRPA	lower teeth appearance	females	0.0 %	1.0
SHIRPA	lower teeth appearance	males	0.0 %	1.00
SHIRPA	lower teeth appearance	both	0.0 %	1.00
SHIRPA	mouth morphology	females	0.0 %	1.0
SHIRPA	mouth morphology	males	0.0 %	1.00
SHIRPA	mouth morphology	both	0.0 %	1.00
SHIRPA	salivation	females	0.0 %	1.0
SHIRPA	salivation	males	0.0 %	1.0
SHIRPA	salivation	both	0.0 %	1.0
SHIRPA	skin color back paws	females	0.0 %	1.0
SHIRPA	skin color back paws	males	0.0 %	1.0
SHIRPA	skin color back paws	both	0.0 %	1.0
SHIRPA	skin color ear	females	0.0 %	1.0
SHIRPA	skin color ear	males	0.0 %	1.0
SHIRPA	skin color ear	both	0.0 %	1.0
SHIRPA	skin color front paws	females	0.0 %	1.0
SHIRPA	skin color front paws	males	0.0 %	1.0
SHIRPA	skin color front paws	both	0.0 %	1.0
SHIRPA	skin color snout	females	0.0 %	1.0
SHIRPA	skin color snout	males	0.0 %	1.0
SHIRPA	skin color snout	both	0.0 %	1.0
SHIRPA	skin color tail	females	0.0 %	1.0
SHIRPA	skin color tail	males	0.0 %	1.0
SHIRPA	skin color tail	both	0.0 %	1.0
SHIRPA	skin color whole body	females	0.0 %	1.0
SHIRPA	skin color whole body	males	0.0 %	1.0
SHIRPA	skin color whole body	both	0.0 %	1.0
SHIRPA	skin texture back paw	females	0.0 %	1.0
SHIRPA	skin texture back paw	males	0.0 %	1.0
SHIRPA	skin texture back paw	both	0.0 %	1.0
SHIRPA	skin texture ear	females	0.0 %	1.0
SHIRPA	skin texture ear	males	0.0 %	1.0
SHIRPA	skin texture ear	both	0.0 %	1.0
SHIRPA	skin texture front paws	females	0.0 %	1.0
SHIRPA	skin texture front paws	males	0.0 %	1.0
SHIRPA	skin texture front paws	both	0.0 %	1.0
SHIRPA	skin texture snout	females	0.0 %	1.0
SHIRPA	skin texture snout	males	0.0 %	1.0
SHIRPA	skin texture snout	both	0.0 %	1.0
SHIRPA	skin texture tail	females	0.0 %	1.0
SHIRPA	skin texture tail	males	0.0 %	1.0
SHIRPA	skin texture tail	both	0.0 %	1.0
SHIRPA	skin texture whole body	females	0.0 %	1.0
SHIRPA	skin texture whole body	males	0.0 %	1.00
SHIRPA	skin texture whole body	both	0.0 %	1.00
SHIRPA	snout size	females	0.0 %	1.0
SHIRPA	snout size	males	1.0 %	1.0
SHIRPA	snout size	both	0.0 %	1.0
SHIRPA	startle response	females	0.0 %	1.00
SHIRPA	startle response	males	0.0 %	1.00
SHIRPA	startle response	both	0.0 %	1.00
SHIRPA	tail curvature	females	0.0 %	1.00
SHIRPA	tail curvature	males	0.0 %	1.0
SHIRPA	tail curvature	both	0.0 %	1.0
SHIRPA	tail elevation	females	1.0 %	1.00
SHIRPA	tail elevation	males	2.0 %	1.0
SHIRPA	tail elevation	both	1.0 %	1.0
SHIRPA	tail length	females	0.0 %	1.0
SHIRPA	tail length	males	0.0 %	1.0
SHIRPA	tail length	both	0.0 %	1.00
SHIRPA	tail morphology	females	0.0 %	1.00
SHIRPA	tail morphology	males	0.0 %	1.0
SHIRPA	tail morphology	both	0.0 %	1.00
SHIRPA	tail presence	females	0.0 %	1.0
SHIRPA	tail presence	males	0.0 %	1.0
SHIRPA	tail presence	both	0.0 %	1.0
SHIRPA	tail shape	females	0.0 %	1.0
SHIRPA	tail shape	males	0.0 %	1.0
SHIRPA	tail shape	both	0.0 %	1.00
SHIRPA	tail thickness	females	0.0 %	1.0
SHIRPA	tail thickness	males	0.0 %	1.0
SHIRPA	tail thickness	both	0.0 %	1.0
SHIRPA	teeth presence	females	0.0 %	1.0
SHIRPA	teeth presence	males	0.0 %	1.00
SHIRPA	teeth presence	both	0.0 %	1.00
SHIRPA	transfer arousal	females	1.0 %	1.0
SHIRPA	transfer arousal	males	2.0 %	1.00
SHIRPA	transfer arousal	both	1.0 %	1.0
SHIRPA	tremor	females	0.0 %	1.0
SHIRPA	tremor	males	0.0 %	1.0
SHIRPA	tremor	both	0.0 %	1.00
SHIRPA	trunk curl	females	0.0 %	1.00
SHIRPA	trunk curl	males	0.0 %	1.0
SHIRPA	trunk curl	both	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	females	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	males	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	both	0.0 %	1.00
SHIRPA	upper lip morphology	females	0.0 %	1.0
SHIRPA	upper lip morphology	males	0.0 %	1.0
SHIRPA	upper lip morphology	both	0.0 %	1.0
SHIRPA	upper teeth appearance	females	0.0 %	1.0
SHIRPA	upper teeth appearance	males	0.0 %	1.0
SHIRPA	upper teeth appearance	both	0.0 %	1.00
SHIRPA	vibrissae appearance	females	2.0 %	1.0
SHIRPA	vibrissae appearance	males	1.0 %	1.0
SHIRPA	vibrissae appearance	both	1.0 %	1.0
SHIRPA	vibrissae presence	females	2.0 %	1.00
SHIRPA	vibrissae presence	males	1.0 %	1.0
SHIRPA	vibrissae presence	both	2.0 %	1.0
SHIRPA	vocalization	females	2.0 %	1.00
SHIRPA	vocalization	males	2.0 %	1.0
SHIRPA	vocalization	both	2.0 %	1.00

GENOTYPE CORRELATION PLOT

Correlate Thap1^em1(IMPC)J/Mmjax -/+ with genotype: