MPD: JaxKOMP-EAP genotype: Arhgap11a<sup>em1(IMPC)J</sup>/Mmjax -/-

JaxKOMP-EAP effect sizes: Arhgap11a^em1(IMPC)J/Mmjax -/- Gene Arhgap11a

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	-1.9892	1.7724	-0.82127	0.715	0.288
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	-2.2501	3.0671	-0.48848	0.831	0.482
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	-2.0762	2.1827	-0.63968	0.723	0.366
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	-4.4631	3.0091	-0.82213	0.555	0.172
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	3.6820	2.6429	0.55915	0.579	0.194
body composition	body length	-0.094531	0.046883	-0.84948	0.241	0.0546
body composition	body weight (at time of DXA)	-0.27105	0.68796	-0.12656	0.843	0.697
body composition	bone area, whole body scan, head excluded	-0.043443	0.15983	-0.0027305	0.909	0.788
body composition	bone mineral content of whole body scan, head excluded	-0.0059763	0.011553	-0.22021	0.816	0.610
body composition	bone mineral content to body weight ratio	-0.0010604	0.00062111	-1.1153	0.313	0.100
body composition	bone mineral density of whole body scan, head excluded	-0.00042914	0.00056395	-0.44828	0.728	0.454
body composition	fat tissue mass of whole body scan, head excluded	0.25255	0.49323	0.42923	0.804	0.613
body composition	fat tissue mass to body weight ratio	0.0089766	0.019744	0.47154	0.822	0.653
body composition	lean tissue mass of whole body scan, head excluded	0.057351	0.47279	-0.030040	0.966	0.904
body composition	lean tissue mass to body weight ratio	-0.016938	0.018060	-0.92853	0.610	0.357
body composition	percent fat, whole body scan, head excluded	1.2382	1.9587	0.64731	0.739	0.533
body composition	ratio of soft-tissue attenuation coefficients	-0.0013763	0.0021818	-0.65741	0.741	0.534
body composition	tissue area	-0.040860	0.32927	0.046486	0.969	0.902
body composition	total tissue mass, whole body scan, head excluded	0.33271	0.30084	0.49764	0.529	0.279
clinical blood chemistry	alanine transaminase (plasma ALT)	15.778	5.6740	1.0133	0.200	0.0119
clinical blood chemistry	albumin (plasma Alb)	0.0094284	0.50268	0.081363	0.994	0.985
clinical blood chemistry	alkaline phosphatase (plasma ALP)	13.855	3.7029	1.5008	0.0200	0.00138
clinical blood chemistry	aspartate transaminase (plasma AST)	71.576	13.887	1.8980	0.00383	0.0000564
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	0.68983	0.21621	1.7042	0.126	0.00507
clinical blood chemistry	blood urea nitrogen (BUN)	-3.1908	1.6227	-1.2524	0.239	0.0649
clinical blood chemistry	calcium (plasma Ca)	0.14850	0.10729	1.3431	0.412	0.182
clinical blood chemistry	creatinine (plasma)	-0.037811	0.037179	-0.73673	0.568	0.323
clinical blood chemistry	glucose (plasma GLU, no fast)	-7.3095	8.0580	0.014997	0.581	0.376
clinical blood chemistry	HDL cholesterol (plasma HDL)	1.9762	2.7735	0.14432	0.754	0.485
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	0.0050674	0.011435	0.13779	0.884	0.663
clinical blood chemistry	phosphorus (plasma phosphate)	0.77084	0.29284	1.0810	0.123	0.0164
clinical blood chemistry	total bilirubin (plasma TBIL)	0.0064994	0.0053831	0.44270	0.589	0.243
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	1.1935	3.5018	-0.020618	0.902	0.737
clinical blood chemistry	total protein (plasma TP)	-0.48810	0.52078	-0.44224	0.626	0.360
clinical blood chemistry	triglyceride (plasma TG, no fast)	-2.8688	9.5452	0.067295	0.898	0.767
glucose tolerance test	amount glucose injected	2.3770	2.7741	1.0258	0.742	0.405
glucose tolerance test	plasma glucose, 0min	7.1841	5.4009	0.52094	0.402	0.195
glucose tolerance test	plasma glucose, 15min	27.224	17.685	0.89608	0.432	0.136
glucose tolerance test	plasma glucose, 30min	38.193	16.090	1.2438	0.173	0.0253
glucose tolerance test	plasma glucose, 60min	30.243	13.733	1.2992	0.231	0.0371
glucose tolerance test	plasma glucose, 120min	14.619	9.5890	0.86374	0.443	0.140
grip strength	body weight (at time of grip strength test)	-0.37652	0.36813	-0.14411	0.501	0.311
grip strength	forelimb and hindlimb grip strength (mean of trials), average	13.627	6.7816	1.2354	0.158	0.0494
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	0.66003	0.35542	1.1610	0.205	0.0687
grip strength	forelimb and hindlimb grip strength by trial, trial1	10.559	8.8820	0.97830	0.536	0.240
grip strength	forelimb and hindlimb grip strength by trial, trial2	9.7957	8.3922	0.85871	0.503	0.248
grip strength	forelimb and hindlimb grip strength by trial, trial3	21.880	9.2492	1.5526	0.130	0.0216
grip strength	forelimb grip strength (mean of trials), average	6.4421	4.2450	1.1192	0.360	0.135
grip strength	forelimb grip strength (mean of trials), average normalized to bw	0.32248	0.20651	1.0588	0.362	0.124
grip strength	forelimb grip strength by trial, trial1	6.5045	5.3409	1.0141	0.587	0.228
grip strength	forelimb grip strength by trial, trial2	4.1004	5.8949	0.68455	0.782	0.490
grip strength	forelimb grip strength by trial, trial3	9.8748	5.4949	1.2672	0.329	0.0777
heart weight	heart weight, normalized to body weight	-0.17231	0.25359	-1.1396	0.695	0.504
heart weight	heart weight, weight	-2.1810	5.3141	-0.66224	0.818	0.685
hematology	basophil differential (percent of total WBC)	0.30054	0.055854	2.5107	0.0111	0.0000342
hematology	calculated hemoglobin (cHGB)	0.32422	0.20917	0.74036	0.397	0.138
hematology	eosinophil differential (percent of total WBC)	0.030635	0.44611	0.15722	0.979	0.946
hematology	hematocrit (HCT)	0.23640	0.53525	-0.12332	0.840	0.664
hematology	hemoglobin concentration distribution width (HDW)	0.049473	0.033070	1.3313	0.439	0.151
hematology	large unstained cells (percent of total WBC)	0.59167	0.49612	2.3377	0.592	0.248
hematology	lymphocyte differential (percent of total WBC)	-3.3564	4.3346	-1.3443	0.675	0.448
hematology	mean corpuscular hemoglobin (CHr)	-0.0088985	0.12223	-0.047717	0.970	0.943
hematology	mean platelet volume (MPV)	-0.11533	0.093133	-0.88626	0.449	0.231
hematology	mean RBC corpuscular hemoglobin (MCH)	-0.043594	0.15211	-0.20257	0.907	0.778
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	-0.025002	0.31814	-0.036991	0.976	0.938
hematology	mean RBC corpuscular volume (MCV)	-0.57481	0.31074	-0.99769	0.226	0.0800
hematology	measured hemoglobin (mHGB)	0.10952	0.12267	0.029405	0.667	0.383
hematology	monocyte differential (percent of total WBC)	0.50009	0.88417	1.5459	0.834	0.579
hematology	neutrophil differential (percent of total WBC)	3.1218	3.5735	1.3968	0.615	0.393
hematology	platelet count (PLT; units per volume x 10³)	7.4405	41.062	0.14677	0.954	0.858
hematology	RBC corpuscular distribution width (RDW)	0.056158	0.22548	0.20354	0.900	0.806
hematology	RBC corpuscular hemoglobin concentration mean (CHCM)	0.38976	0.26256	0.96188	0.380	0.154
hematology	red blood cell count (RBC; per volume x 10⁶)	0.090312	0.12602	0.049277	0.716	0.482
hematology	reticulocyte count (Retic; units per volume x 10⁹)	-12.054	14.490	-0.43727	0.761	0.416
hematology	reticulocyte differential (percent of total RBC)	-0.14655	0.13981	-0.42635	0.676	0.308
hematology	white blood cell count (WBC; units per volume x 10³)	-1.4575	0.45678	-0.82000	0.0351	0.00481
holeboard	number of hole pokes by individual hole number, 20 min test, 1	0.17128	0.69273	0.22036	0.943	0.805
holeboard	number of hole pokes by individual hole number, 20 min test, 2	-0.36713	0.39803	-0.46808	0.807	0.359
holeboard	number of hole pokes by individual hole number, 20 min test, 3	0.25918	0.51728	0.51378	0.918	0.618
holeboard	number of hole pokes by individual hole number, 20 min test, 4	-0.18220	0.94843	-0.081958	0.954	0.848
holeboard	number of hole pokes by individual hole number, 20 min test, 5	-0.33251	0.41107	-0.44187	0.841	0.421
holeboard	number of hole pokes by individual hole number, 20 min test, 6	0.13070	0.23181	0.39643	0.930	0.575
holeboard	number of hole pokes by individual hole number, 20 min test, 7	-0.011898	0.27009	-0.060040	1.00	0.965
holeboard	number of hole pokes by individual hole number, 20 min test, 8	-0.035915	0.46125	0.076878	0.987	0.938
holeboard	number of hole pokes by individual hole number, 20 min test, 9	0.62353	0.38931	1.1357	0.563	0.113
holeboard	number of hole pokes by individual hole number, 20 min test, 10	0.39458	0.24692	1.0059	0.711	0.114
holeboard	number of hole pokes by individual hole number, 20 min test, 11	0.070173	0.28279	0.21273	0.969	0.805
holeboard	number of hole pokes by individual hole number, 20 min test, 12	-0.040249	0.38405	0.040495	0.978	0.917
holeboard	number of hole pokes by individual hole number, 20 min test, 13	-1.0990	0.65906	-0.98007	0.495	0.0996
holeboard	number of hole pokes by individual hole number, 20 min test, 14	0.036648	0.59858	0.12855	0.987	0.951
holeboard	number of hole pokes by individual hole number, 20 min test, 15	0.38130	0.46520	0.66710	0.819	0.415
holeboard	number of hole pokes by individual hole number, 20 min test, 16	-0.21341	0.85605	-0.17463	0.944	0.804
holeboard	total number of hole pokes, 20 min test	-0.19948	4.4237	0.059073	0.982	0.964
light / dark	fecal boli count, 20 min test	0.69114	0.66331	0.79124	0.709	0.301
light / dark	latency to enter dark zone, 20 min test	9.8340	30.745	0.086637	0.934	0.750
light / dark	number of transitions between light and dark zones, 20 min test	-0.56101	6.7141	0.069007	0.972	0.934
light / dark	percentage of total time in dark zone, 20 min test	-0.49473	2.3012	0.043278	0.946	0.830
light / dark	percentage of total time in light zone, 20 min test	0.49473	2.3012	-0.050045	0.947	0.830
light / dark	time mobile in dark zone, 20 min test	1.2405	9.4213	-0.0027040	0.959	0.896
light / dark	time mobile in light zone, 20 min test	14.751	9.8218	0.62523	0.369	0.137
light / dark	time spent in dark zone, 20 min test	-17.248	34.175	-0.056815	0.879	0.615
light / dark	time spent in light zone, 20 min test	17.248	34.175	0.056815	0.879	0.615
open field	average speed in center of arena, 20 min test	-0.074432	0.33957	-0.23509	0.943	0.827
open field	average speed in periphery of arena, 20 min test	0.19758	0.11645	0.26001	0.249	0.0939
open field	distance traveled habituation ratio, 20 min test	9.1249	7.3187	0.73781	0.538	0.216
open field	distance traveled in center of arena, 20 min test	90.809	74.155	0.24199	0.479	0.225
open field	distance traveled in periphery of arena, 20 min test	166.98	130.90	0.22131	0.437	0.206
open field	distance traveled slope, 20 min test	7.4375	6.9610	0.66734	0.614	0.289
open field	distance traveled, 20 min test, 1st 5min	17.989	58.090	-0.18840	0.892	0.758
open field	distance traveled, 20 min test, 2nd 5min	80.624	45.643	0.41068	0.257	0.0814
open field	distance traveled, 20 min test, 3rd 5min	64.011	43.699	0.27253	0.361	0.147
open field	distance traveled, 20 min test, 4th 5min	101.42	44.384	0.62108	0.131	0.0251
open field	number of clockwise revolution episodes, 20 min test	1.2090	0.94453	0.29856	0.560	0.204
open field	number of counter-clockwise revolution episodes, 20 min test	1.1793	0.82897	0.20483	0.431	0.159
open field	number of fecal boli, 20 min test	-1.3624	0.78048	-0.83349	0.344	0.0851
open field	number of rears in 5 min bins, 20 min test, 1st 5min	-0.13489	1.4765	-0.24697	0.964	0.927
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	1.4615	2.3355	0.0087270	0.761	0.533
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	2.9573	2.4515	0.39466	0.506	0.231
open field	number of rears in 5 min bins, 20 min test, 4th 5min	3.4772	2.8073	0.42386	0.489	0.219
open field	percentage of total time in center of arena, 20 min test	2.2944	2.3533	0.32164	0.648	0.333
open field	percentage of total time in center of arena, slope, 20 min test	-1.0039	0.87228	-0.41507	0.710	0.253
open field	percentage of total time in center, habituation ratio, 20 min test	-1.1244	0.87893	-0.50006	0.683	0.205
open field	percentage of total time in corners of arena, 20 min test	-6.0430	3.5875	-0.83666	0.379	0.0962
open field	percentage of total time in corners, habituation ratio, 20 min test	1.5520	1.5835	0.41653	0.798	0.330
open field	percentage of total time in corners, slope, 20 min test	2.0544	1.5559	0.66734	0.671	0.191
open field	permanence time in center of arena, 20 min test	27.540	28.239	0.32164	0.648	0.333
open field	permanence time in corners of arena, 20 min test	-72.527	43.049	-0.83666	0.379	0.0961
open field	permanence time in periphery of arena, 20 min test	-27.535	28.240	-0.32164	0.648	0.333
open field	total distance traveled, 20 min test	255.71	149.59	0.24753	0.247	0.0915
open field	total number of rears, 20 min test	7.8500	7.9141	0.20072	0.583	0.324
open field	whole arena average speed, 20 min test	0.21342	0.12457	0.24891	0.246	0.0908
open field	whole arena resting time, 20 min test	-31.992	15.174	-0.33581	0.135	0.0383
open field	whole arena time spent mobile, 20 min test	32.002	15.159	0.58724	0.136	0.0381
open field	whole arena time spent vertical, 20 min test	-2.4772	8.5679	-0.31458	0.909	0.773
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	2.3895	1.2229	1.1812	0.272	0.0557
startle / PPI	average baseline movement during background noise	-2.3494	1.7010	-1.5243	0.720	0.175
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	0.12158	0.057974	1.0019	0.286	0.0424
startle / PPI	average of each corrected percent pre-pulse inhibition value	0.16288	0.13785	1.4638	0.592	0.244
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	6.0552	8.4503	0.70875	0.891	0.478
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	13.087	6.6132	1.2717	0.346	0.0546
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	13.402	5.6987	1.2655	0.162	0.0237
startle / PPI	average startle response to full pulse (120 dB)	-74.168	42.636	-1.0790	0.263	0.0894
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-78.447	46.604	-1.1148	0.281	0.0999
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-88.265	42.353	-1.3689	0.162	0.0434
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-80.185	34.326	-1.4767	0.115	0.0246
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	-5.0813	1.3987	-2.7709	0.173	0.000773
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	-2.4448	1.4975	-1.5378	0.613	0.110
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	-2.7056	2.5820	-1.4979	0.718	0.301
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.15128	0.23674	1.4851	0.918	0.526
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.20239	0.16523	1.6098	0.571	0.228
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.13576	0.067250	0.84883	0.205	0.0503
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	-71.736	43.038	-1.0445	0.285	0.103
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	-74.314	46.810	-1.0765	0.316	0.120
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	-85.955	42.539	-1.3204	0.176	0.0499
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	-74.390	34.459	-1.3305	0.150	0.0369
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.040165	0.096076	0.39159	0.941	0.678
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.15447	0.075246	1.1118	0.296	0.0465
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.15042	0.071018	0.88559	0.186	0.0403
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	-250.96	154.80	-1.0066	0.302	0.113
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	-245.43	162.56	-1.0112	0.344	0.139
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	-309.96	157.03	-1.2876	0.187	0.0552
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	-284.48	125.44	-1.3980	0.126	0.0288
startle / PPI	maximum baseline movement during background noise	-4.1655	3.4220	-1.1359	0.726	0.230
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	5.8231	8.6304	0.62986	0.917	0.504
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	14.419	6.9768	1.2593	0.318	0.0451
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	16.079	5.8259	1.3512	0.0989	0.00868
startle / PPI	maximum startle response to full pulse (120 dB)	-254.63	154.01	-1.0183	0.290	0.106
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-255.28	161.69	-1.0567	0.320	0.122
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-313.66	156.29	-1.3104	0.179	0.0514
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-296.61	124.50	-1.4767	0.107	0.0220
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	-12.033	3.1045	-2.5737	0.0984	0.000376
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	-4.2634	4.1007	-1.1466	0.770	0.305
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	-6.2313	5.8129	-1.4482	0.671	0.290

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Sex	Trait Effect	P-value
eye morphology	anterior chamber depth	females	1.0 %	1.0
eye morphology	anterior chamber depth	males	0.0 %	1.0
eye morphology	anterior chamber depth	both	1.0 %	1.0
eye morphology	bulging eye	females	1.0 %	1.0
eye morphology	bulging eye	males	0.0 %	1.0
eye morphology	bulging eye	both	1.0 %	1.00
eye morphology	cornea	females	4.0 %	1.0
eye morphology	cornea	males	14.0 %	0.0693
eye morphology	cornea	both	6.0 %	0.308
eye morphology	cornea opacity	females	13.0 %	0.171
eye morphology	cornea opacity	males	1.0 %	1.0
eye morphology	cornea opacity	both	7.0 %	0.218
eye morphology	cornea vascularization	females	3.0 %	1.0
eye morphology	cornea vascularization	males	1.0 %	1.0
eye morphology	cornea vascularization	both	2.0 %	1.0
eye morphology	corneal deposits	females	2.0 %	1.0
eye morphology	corneal deposits	males	1.0 %	1.0
eye morphology	corneal deposits	both	1.0 %	1.00
eye morphology	corneal mineralization	females	2.0 %	1.0
eye morphology	corneal mineralization	males	1.0 %	1.0
eye morphology	corneal mineralization	both	1.0 %	1.00
eye morphology	corneal scleralization	females	14.0 %	0.129
eye morphology	corneal scleralization	males	1.0 %	1.0
eye morphology	corneal scleralization	both	7.0 %	0.123
eye morphology	corneal ulcer	females	1.0 %	1.0
eye morphology	corneal ulcer	males	1.0 %	1.0
eye morphology	corneal ulcer	both	1.0 %	1.00
eye morphology	eye closure	females	1.0 %	1.0
eye morphology	eye closure	males	0.0 %	1.0
eye morphology	eye closure	both	1.0 %	1.00
eye morphology	eye hemorrhage or blood presence	females	2.0 %	1.0
eye morphology	eye hemorrhage or blood presence	males	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	both	1.0 %	1.0
eye morphology	eyelid morphology	females	1.0 %	1.0
eye morphology	eyelid morphology	males	0.0 %	1.0
eye morphology	eyelid morphology	both	1.0 %	1.00
eye morphology	eyes (present, absent)	females	1.0 %	1.0
eye morphology	eyes (present, absent)	males	0.0 %	1.0
eye morphology	eyes (present, absent)	both	0.0 %	1.00
eye morphology	fusion between cornea and lens	females	4.0 %	1.0
eye morphology	fusion between cornea and lens	males	2.0 %	1.0
eye morphology	fusion between cornea and lens	both	3.0 %	1.0
eye morphology	iris pigmentation	females	2.0 %	1.0
eye morphology	iris pigmentation	males	1.0 %	1.0
eye morphology	iris pigmentation	both	2.0 %	1.0
eye morphology	iris transillumination	females	2.0 %	1.0
eye morphology	iris transillumination	males	1.0 %	1.00
eye morphology	iris transillumination	both	1.0 %	1.00
eye morphology	irispupil	females	4.0 %	1.0
eye morphology	irispupil	males	13.0 %	0.111
eye morphology	irispupil	both	6.0 %	0.268
eye morphology	lacrimation	females	3.0 %	1.00
eye morphology	lacrimation	males	2.0 %	1.0
eye morphology	lacrimation	both	3.0 %	1.00
eye morphology	lens	females	10.0 %	1.0
eye morphology	lens	males	8.0 %	1.00
eye morphology	lens	both	9.0 %	1.00
eye morphology	lens opacity	females	20.0 %	0.0463
eye morphology	lens opacity	males	6.0 %	1.00
eye morphology	lens opacity	both	7.0 %	0.127
eye morphology	narrow eye opening	females	2.0 %	1.00
eye morphology	narrow eye opening	males	1.0 %	1.0
eye morphology	narrow eye opening	both	1.0 %	1.00
eye morphology	optic disc	females	4.0 %	1.0
eye morphology	optic disc	males	2.0 %	1.00
eye morphology	optic disc	both	3.0 %	1.00
eye morphology	persistence of hyaloid vascular system	females	14.0 %	1.0
eye morphology	persistence of hyaloid vascular system	males	13.0 %	0.115
eye morphology	persistence of hyaloid vascular system	both	6.0 %	0.505
eye morphology	pupil dilation	females	2.0 %	1.0
eye morphology	pupil dilation	males	1.0 %	1.00
eye morphology	pupil dilation	both	2.0 %	1.00
eye morphology	pupil light response	females	2.0 %	1.0
eye morphology	pupil light response	males	1.0 %	1.0
eye morphology	pupil light response	both	2.0 %	1.0
eye morphology	pupil position	females	4.0 %	1.0
eye morphology	pupil position	males	13.0 %	0.112
eye morphology	pupil position	both	6.0 %	0.285
eye morphology	pupil shape	females	3.0 %	1.0
eye morphology	pupil shape	males	2.0 %	1.0
eye morphology	pupil shape	both	3.0 %	1.0
eye morphology	retina	females	10.0 %	1.0
eye morphology	retina	males	16.0 %	1.0
eye morphology	retina	both	13.0 %	1.00
eye morphology	retinal blood vessels	females	4.0 %	1.0
eye morphology	retinal blood vessels	males	2.0 %	1.0
eye morphology	retinal blood vessels	both	3.0 %	1.00
eye morphology	retinal blood vessels pattern	females	5.0 %	1.0
eye morphology	retinal blood vessels pattern	males	2.0 %	1.00
eye morphology	retinal blood vessels pattern	both	4.0 %	1.00
eye morphology	retinal blood vessels structure	females	4.0 %	1.0
eye morphology	retinal blood vessels structure	males	2.0 %	1.0
eye morphology	retinal blood vessels structure	both	3.0 %	1.0
eye morphology	retinal pigmentation	females	12.0 %	1.0
eye morphology	retinal pigmentation	males	14.0 %	1.0
eye morphology	retinal pigmentation	both	13.0 %	1.00
eye morphology	retinal structure	females	4.0 %	1.0
eye morphology	retinal structure	males	2.0 %	1.00
eye morphology	retinal structure	both	3.0 %	1.00
eye morphology	synechia	females	4.0 %	1.0
eye morphology	synechia	males	2.0 %	1.00
eye morphology	synechia	both	3.0 %	1.00
eye morphology	vitreous	females	4.0 %	1.0
eye morphology	vitreous	males	2.0 %	1.0
eye morphology	vitreous	both	3.0 %	1.0
SHIRPA	activity body position	females	1.0 %	1.0
SHIRPA	activity body position	males	2.0 %	1.0
SHIRPA	activity body position	both	1.0 %	1.00
SHIRPA	aggression	females	0.0 %	1.00
SHIRPA	aggression	males	1.0 %	1.0
SHIRPA	aggression	both	1.0 %	1.00
SHIRPA	body length	females	0.0 %	1.0
SHIRPA	body length	males	0.0 %	1.0
SHIRPA	body length	both	0.0 %	1.0
SHIRPA	body position	females	0.0 %	1.0
SHIRPA	body position	males	1.0 %	1.0
SHIRPA	body position	both	0.0 %	1.00
SHIRPA	body thickness	females	1.0 %	1.0
SHIRPA	body thickness	males	0.0 %	1.0
SHIRPA	body thickness	both	0.0 %	1.00
SHIRPA	coat color abdomen	females	3.0 %	1.00
SHIRPA	coat color abdomen	males	4.0 %	1.00
SHIRPA	coat color abdomen	both	4.0 %	1.00
SHIRPA	coat color back	females	0.0 %	1.0
SHIRPA	coat color back	males	0.0 %	1.0
SHIRPA	coat color back	both	0.0 %	1.00
SHIRPA	coat color head	females	0.0 %	1.0
SHIRPA	coat color head	males	0.0 %	1.0
SHIRPA	coat color head	both	0.0 %	1.0
SHIRPA	coat color pattern abdomen	females	1.0 %	1.0
SHIRPA	coat color pattern abdomen	males	1.0 %	1.0
SHIRPA	coat color pattern abdomen	both	1.0 %	1.00
SHIRPA	coat color pattern back	females	0.0 %	1.0
SHIRPA	coat color pattern back	males	0.0 %	1.0
SHIRPA	coat color pattern back	both	0.0 %	1.00
SHIRPA	coat color pattern head	females	0.0 %	1.0
SHIRPA	coat color pattern head	males	0.0 %	1.00
SHIRPA	coat color pattern head	both	0.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	females	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	males	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	both	2.0 %	1.0
SHIRPA	coat hair back texture appearance	females	0.0 %	1.0
SHIRPA	coat hair back texture appearance	males	0.0 %	1.0
SHIRPA	coat hair back texture appearance	both	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	females	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	males	1.0 %	1.0
SHIRPA	coat hair distribution abdomen	both	1.0 %	1.0
SHIRPA	coat hair distribution back	females	0.0 %	1.0
SHIRPA	coat hair distribution back	males	0.0 %	1.0
SHIRPA	coat hair distribution back	both	0.0 %	1.00
SHIRPA	coat hair distribution head	females	1.0 %	1.00
SHIRPA	coat hair distribution head	males	1.0 %	1.0
SHIRPA	coat hair distribution head	both	1.0 %	1.0
SHIRPA	coat hair head texture appearance	females	0.0 %	1.00
SHIRPA	coat hair head texture appearance	males	0.0 %	1.0
SHIRPA	coat hair head texture appearance	both	0.0 %	1.0
SHIRPA	contact righting	females	5.0 %	1.0
SHIRPA	contact righting	males	5.0 %	1.00
SHIRPA	contact righting	both	5.0 %	1.00
SHIRPA	ear morphology	females	0.0 %	1.0
SHIRPA	ear morphology	males	0.0 %	1.0
SHIRPA	ear morphology	both	0.0 %	1.0
SHIRPA	fat distribution	females	0.0 %	1.0
SHIRPA	fat distribution	males	0.0 %	1.0
SHIRPA	fat distribution	both	0.0 %	1.0
SHIRPA	forelimb digit number	females	0.0 %	1.00
SHIRPA	forelimb digit number	males	0.0 %	1.0
SHIRPA	forelimb digit number	both	0.0 %	1.0
SHIRPA	forelimb digit position	females	0.0 %	1.0
SHIRPA	forelimb digit position	males	0.0 %	1.0
SHIRPA	forelimb digit position	both	0.0 %	1.0
SHIRPA	forelimb digit shape	females	0.0 %	1.0
SHIRPA	forelimb digit shape	males	0.0 %	1.0
SHIRPA	forelimb digit shape	both	0.0 %	1.0
SHIRPA	forelimb digit size	females	0.0 %	1.0
SHIRPA	forelimb digit size	males	0.0 %	1.0
SHIRPA	forelimb digit size	both	0.0 %	1.0
SHIRPA	forelimb footpads	females	0.0 %	1.0
SHIRPA	forelimb footpads	males	0.0 %	1.0
SHIRPA	forelimb footpads	both	0.0 %	1.0
SHIRPA	forelimb nail length	females	0.0 %	1.0
SHIRPA	forelimb nail length	males	0.0 %	1.0
SHIRPA	forelimb nail length	both	0.0 %	1.0
SHIRPA	forelimb nail number	females	0.0 %	1.0
SHIRPA	forelimb nail number	males	0.0 %	1.0
SHIRPA	forelimb nail number	both	0.0 %	1.0
SHIRPA	forelimb nail position	females	0.0 %	1.0
SHIRPA	forelimb nail position	males	0.0 %	1.0
SHIRPA	forelimb nail position	both	0.0 %	1.0
SHIRPA	forelimb nail shape	females	0.0 %	1.0
SHIRPA	forelimb nail shape	males	0.0 %	1.0
SHIRPA	forelimb nail shape	both	0.0 %	1.0
SHIRPA	forelimbs position	females	0.0 %	1.0
SHIRPA	forelimbs position	males	0.0 %	1.0
SHIRPA	forelimbs position	both	0.0 %	1.0
SHIRPA	forelimbs shape	females	0.0 %	1.0
SHIRPA	forelimbs shape	males	0.0 %	1.0
SHIRPA	forelimbs shape	both	0.0 %	1.0
SHIRPA	forelimbs size	females	0.0 %	1.0
SHIRPA	forelimbs size	males	0.0 %	1.00
SHIRPA	forelimbs size	both	0.0 %	1.0
SHIRPA	forepaw position	females	0.0 %	1.0
SHIRPA	forepaw position	males	0.0 %	1.0
SHIRPA	forepaw position	both	0.0 %	1.0
SHIRPA	forepaw shape	females	0.0 %	1.0
SHIRPA	forepaw shape	males	0.0 %	1.0
SHIRPA	forepaw shape	both	0.0 %	1.0
SHIRPA	forepaw size	females	0.0 %	1.0
SHIRPA	forepaw size	males	0.0 %	1.0
SHIRPA	forepaw size	both	0.0 %	1.0
SHIRPA	gait (fluidity)	females	0.0 %	1.0
SHIRPA	gait (fluidity)	males	0.0 %	1.0
SHIRPA	gait (fluidity)	both	0.0 %	1.0
SHIRPA	genitalia morphology	females	0.0 %	1.00
SHIRPA	genitalia morphology	males	0.0 %	1.0
SHIRPA	genitalia morphology	both	0.0 %	1.00
SHIRPA	genitalia presence	females	0.0 %	1.0
SHIRPA	genitalia presence	males	0.0 %	1.0
SHIRPA	genitalia presence	both	0.0 %	1.0
SHIRPA	genitalia size	females	0.0 %	1.0
SHIRPA	genitalia size	males	0.0 %	1.00
SHIRPA	genitalia size	both	0.0 %	1.00
SHIRPA	head bobbing	females	0.0 %	1.0
SHIRPA	head bobbing	males	0.0 %	1.0
SHIRPA	head bobbing	both	0.0 %	1.0
SHIRPA	head morphology	females	0.0 %	1.0
SHIRPA	head morphology	males	0.0 %	1.0
SHIRPA	head morphology	both	0.0 %	1.0
SHIRPA	head size	females	0.0 %	1.0
SHIRPA	head size	males	0.0 %	1.00
SHIRPA	head size	both	0.0 %	1.0
SHIRPA	hindlimb digit number	females	1.0 %	1.00
SHIRPA	hindlimb digit number	males	0.0 %	1.0
SHIRPA	hindlimb digit number	both	0.0 %	1.0
SHIRPA	hindlimb digit position	females	0.0 %	1.0
SHIRPA	hindlimb digit position	males	0.0 %	1.0
SHIRPA	hindlimb digit position	both	0.0 %	1.0
SHIRPA	hindlimb digit shape	females	0.0 %	1.0
SHIRPA	hindlimb digit shape	males	0.0 %	1.0
SHIRPA	hindlimb digit shape	both	0.0 %	1.00
SHIRPA	hindlimb digit size	females	0.0 %	1.00
SHIRPA	hindlimb digit size	males	0.0 %	1.00
SHIRPA	hindlimb digit size	both	0.0 %	1.00
SHIRPA	hindlimb nail length	females	0.0 %	1.0
SHIRPA	hindlimb nail length	males	0.0 %	1.00
SHIRPA	hindlimb nail length	both	0.0 %	1.0
SHIRPA	hindlimb nail number	females	0.0 %	1.0
SHIRPA	hindlimb nail number	males	1.0 %	1.00
SHIRPA	hindlimb nail number	both	0.0 %	1.0
SHIRPA	hindlimb nail position	females	0.0 %	1.0
SHIRPA	hindlimb nail position	males	0.0 %	1.0
SHIRPA	hindlimb nail position	both	0.0 %	1.0
SHIRPA	hindlimb nail shape	females	0.0 %	1.0
SHIRPA	hindlimb nail shape	males	0.0 %	1.0
SHIRPA	hindlimb nail shape	both	0.0 %	1.0
SHIRPA	hindlimbs footpads	females	0.0 %	1.0
SHIRPA	hindlimbs footpads	males	0.0 %	1.0
SHIRPA	hindlimbs footpads	both	0.0 %	1.0
SHIRPA	hindlimbs position	females	0.0 %	1.0
SHIRPA	hindlimbs position	males	0.0 %	1.0
SHIRPA	hindlimbs position	both	0.0 %	1.0
SHIRPA	hindlimbs shape	females	0.0 %	1.0
SHIRPA	hindlimbs shape	males	0.0 %	1.0
SHIRPA	hindlimbs shape	both	0.0 %	1.0
SHIRPA	hindlimbs size	females	0.0 %	1.0
SHIRPA	hindlimbs size	males	0.0 %	1.0
SHIRPA	hindlimbs size	both	0.0 %	1.0
SHIRPA	hindpaw position	females	0.0 %	1.0
SHIRPA	hindpaw position	males	0.0 %	1.0
SHIRPA	hindpaw position	both	0.0 %	1.0
SHIRPA	hindpaw shape	females	0.0 %	1.0
SHIRPA	hindpaw shape	males	0.0 %	1.0
SHIRPA	hindpaw shape	both	0.0 %	1.0
SHIRPA	hindpaw size	females	0.0 %	1.0
SHIRPA	hindpaw size	males	0.0 %	1.0
SHIRPA	hindpaw size	both	0.0 %	1.0
SHIRPA	limb grasp	females	4.0 %	0.524
SHIRPA	limb grasp	males	6.0 %	1.0
SHIRPA	limb grasp	both	1.0 %	1.0
SHIRPA	lower lip morphology	females	0.0 %	1.0
SHIRPA	lower lip morphology	males	0.0 %	1.0
SHIRPA	lower lip morphology	both	0.0 %	1.0
SHIRPA	lower teeth appearance	females	0.0 %	1.0
SHIRPA	lower teeth appearance	males	0.0 %	1.0
SHIRPA	lower teeth appearance	both	0.0 %	1.0
SHIRPA	mouth morphology	females	0.0 %	1.0
SHIRPA	mouth morphology	males	0.0 %	1.0
SHIRPA	mouth morphology	both	0.0 %	1.0
SHIRPA	salivation	females	0.0 %	1.0
SHIRPA	salivation	males	0.0 %	1.0
SHIRPA	salivation	both	0.0 %	1.0
SHIRPA	skin color back paws	females	0.0 %	1.0
SHIRPA	skin color back paws	males	0.0 %	1.0
SHIRPA	skin color back paws	both	0.0 %	1.0
SHIRPA	skin color ear	females	0.0 %	1.0
SHIRPA	skin color ear	males	0.0 %	1.0
SHIRPA	skin color ear	both	0.0 %	1.0
SHIRPA	skin color front paws	females	0.0 %	1.0
SHIRPA	skin color front paws	males	0.0 %	1.0
SHIRPA	skin color front paws	both	0.0 %	1.0
SHIRPA	skin color snout	females	0.0 %	1.0
SHIRPA	skin color snout	males	0.0 %	1.0
SHIRPA	skin color snout	both	0.0 %	1.0
SHIRPA	skin color tail	females	0.0 %	1.0
SHIRPA	skin color tail	males	0.0 %	1.0
SHIRPA	skin color tail	both	0.0 %	1.0
SHIRPA	skin color whole body	females	0.0 %	1.0
SHIRPA	skin color whole body	males	0.0 %	1.0
SHIRPA	skin color whole body	both	0.0 %	1.0
SHIRPA	skin texture back paw	females	0.0 %	1.0
SHIRPA	skin texture back paw	males	0.0 %	1.0
SHIRPA	skin texture back paw	both	0.0 %	1.0
SHIRPA	skin texture ear	females	0.0 %	1.0
SHIRPA	skin texture ear	males	0.0 %	1.0
SHIRPA	skin texture ear	both	0.0 %	1.0
SHIRPA	skin texture front paws	females	0.0 %	1.0
SHIRPA	skin texture front paws	males	0.0 %	1.0
SHIRPA	skin texture front paws	both	0.0 %	1.0
SHIRPA	skin texture snout	females	0.0 %	1.0
SHIRPA	skin texture snout	males	0.0 %	1.0
SHIRPA	skin texture snout	both	0.0 %	1.0
SHIRPA	skin texture tail	females	0.0 %	1.0
SHIRPA	skin texture tail	males	0.0 %	1.0
SHIRPA	skin texture tail	both	0.0 %	1.0
SHIRPA	skin texture whole body	females	0.0 %	1.0
SHIRPA	skin texture whole body	males	0.0 %	1.0
SHIRPA	skin texture whole body	both	0.0 %	1.00
SHIRPA	snout size	females	0.0 %	1.0
SHIRPA	snout size	males	1.0 %	1.0
SHIRPA	snout size	both	0.0 %	1.0
SHIRPA	startle response	females	0.0 %	1.00
SHIRPA	startle response	males	0.0 %	1.00
SHIRPA	startle response	both	0.0 %	1.0
SHIRPA	tail curvature	females	0.0 %	1.00
SHIRPA	tail curvature	males	0.0 %	1.0
SHIRPA	tail curvature	both	0.0 %	1.00
SHIRPA	tail elevation	females	1.0 %	1.00
SHIRPA	tail elevation	males	2.0 %	1.0
SHIRPA	tail elevation	both	1.0 %	1.0
SHIRPA	tail length	females	0.0 %	1.0
SHIRPA	tail length	males	0.0 %	1.00
SHIRPA	tail length	both	0.0 %	1.0
SHIRPA	tail morphology	females	0.0 %	1.00
SHIRPA	tail morphology	males	0.0 %	1.00
SHIRPA	tail morphology	both	0.0 %	1.00
SHIRPA	tail presence	females	0.0 %	1.0
SHIRPA	tail presence	males	0.0 %	1.0
SHIRPA	tail presence	both	0.0 %	1.0
SHIRPA	tail shape	females	0.0 %	1.0
SHIRPA	tail shape	males	0.0 %	1.0
SHIRPA	tail shape	both	0.0 %	1.0
SHIRPA	tail thickness	females	0.0 %	1.0
SHIRPA	tail thickness	males	0.0 %	1.0
SHIRPA	tail thickness	both	0.0 %	1.0
SHIRPA	teeth presence	females	0.0 %	1.0
SHIRPA	teeth presence	males	0.0 %	1.0
SHIRPA	teeth presence	both	0.0 %	1.0
SHIRPA	transfer arousal	females	1.0 %	1.0
SHIRPA	transfer arousal	males	2.0 %	1.0
SHIRPA	transfer arousal	both	1.0 %	1.0
SHIRPA	tremor	females	0.0 %	1.0
SHIRPA	tremor	males	0.0 %	1.0
SHIRPA	tremor	both	0.0 %	1.00
SHIRPA	trunk curl	females	0.0 %	1.00
SHIRPA	trunk curl	males	0.0 %	1.0
SHIRPA	trunk curl	both	0.0 %	1.00
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	females	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	males	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	both	0.0 %	1.0
SHIRPA	upper lip morphology	females	0.0 %	1.0
SHIRPA	upper lip morphology	males	0.0 %	1.0
SHIRPA	upper lip morphology	both	0.0 %	1.0
SHIRPA	upper teeth appearance	females	0.0 %	1.0
SHIRPA	upper teeth appearance	males	0.0 %	1.00
SHIRPA	upper teeth appearance	both	0.0 %	1.0
SHIRPA	vibrissae appearance	females	2.0 %	1.0
SHIRPA	vibrissae appearance	males	1.0 %	1.0
SHIRPA	vibrissae appearance	both	1.0 %	1.0
SHIRPA	vibrissae presence	females	2.0 %	1.00
SHIRPA	vibrissae presence	males	1.0 %	1.0
SHIRPA	vibrissae presence	both	2.0 %	1.0
SHIRPA	vocalization	females	2.0 %	1.00
SHIRPA	vocalization	males	2.0 %	1.0
SHIRPA	vocalization	both	2.0 %	1.0

GENOTYPE CORRELATION PLOT

Correlate Arhgap11a^em1(IMPC)J/Mmjax -/- with genotype: