MPD: JaxKOMP-EAP genotype: Mylk4<sup>em1(IMPC)J</sup>/Mmjax -/-

JaxKOMP-EAP effect sizes: Mylk4^em1(IMPC)J/Mmjax -/- Gene Mylk4

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

In this plot, data points are the computed genotype effect size vs. C57BL/6NJ controls, for all measured numeric phenotypes in JaxKOMP-EAP

Dimensions Width: × Height: px

Plot Options Group by Procedure Standard Error Show Effect Sizes RankZ

Significance Threshold p-Value Threshold Adjusted Unadjusted

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Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value

ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	0.80059	1.3473	-0.031698	0.856	0.560
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	-2.1291	1.3798	-0.46151	0.623	0.140
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	-1.2082	1.7235	-0.45948	0.803	0.492
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	0.39538	3.0976	-0.068313	0.967	0.900
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	-0.92655	2.9915	-0.16477	0.901	0.760
body composition	body length	-0.034801	0.036359	-0.21242	0.635	0.344
body composition	body weight (at time of DXA)	4.5927	3.0112	2.9415	0.319	0.134
body composition	bone area, whole body scan, head excluded	-0.34581	0.15223	-1.0829	0.153	0.0279
body composition	bone mineral content of whole body scan, head excluded	-0.027188	0.012514	-1.2381	0.178	0.0351
body composition	bone mineral content to body weight ratio	-0.0025732	0.00065916	-2.2577	0.00861	0.000314
body composition	bone mineral density of whole body scan, head excluded	-0.0010884	0.00065382	-1.1227	0.340	0.103
body composition	fat tissue mass of whole body scan, head excluded	1.3955	0.37383	1.7929	0.0129	0.000529
body composition	fat tissue mass to body weight ratio	0.033890	0.014402	1.3689	0.117	0.0230
body composition	lean tissue mass of whole body scan, head excluded	-0.21246	0.35077	-0.61730	0.791	0.548
body composition	lean tissue mass to body weight ratio	-0.077517	0.024432	-2.7194	0.0408	0.00272
body composition	percent fat, whole body scan, head excluded	4.0069	1.1964	1.6763	0.0263	0.00165
body composition	ratio of soft-tissue attenuation coefficients	-0.0044784	0.0013653	-1.6922	0.0289	0.00201
body composition	tissue area	0.69822	0.21084	1.9226	0.0330	0.00183
body composition	total tissue mass, whole body scan, head excluded	1.3484	0.25400	2.2406	0.000430	0.00000327
clinical blood chemistry	alanine transaminase (plasma ALT)	1.6528	4.1614	0.16153	0.912	0.694
clinical blood chemistry	albumin (plasma Alb)	0.51607	0.33446	0.77173	0.441	0.132
clinical blood chemistry	alkaline phosphatase (plasma ALP)	-3.3248	1.9337	-1.1052	0.289	0.0946
clinical blood chemistry	aspartate transaminase (plasma AST)	-41.083	25.424	-1.6254	0.419	0.115
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	-0.89309	0.39885	-2.1071	0.299	0.0318
clinical blood chemistry	blood urea nitrogen (BUN)	1.5768	0.92780	0.60631	0.310	0.0981
clinical blood chemistry	calcium (plasma Ca)	-0.095938	0.051154	-0.32182	0.227	0.0691
clinical blood chemistry	creatinine (plasma)	0.020987	0.011788	0.62094	0.272	0.0842
clinical blood chemistry	glucose (plasma GLU, no fast)	-0.91865	8.8455	0.26368	0.953	0.918
clinical blood chemistry	HDL cholesterol (plasma HDL)	5.7839	2.6678	0.99688	0.205	0.0372
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	-0.0029711	0.0060088	-0.33723	0.866	0.624
clinical blood chemistry	phosphorus (plasma phosphate)	-0.68601	0.24099	-1.1309	0.0792	0.00744
clinical blood chemistry	total bilirubin (plasma TBIL)	-0.024649	0.0084591	-1.5938	0.0885	0.00627
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	8.7196	3.3966	1.1486	0.121	0.0148
clinical blood chemistry	total protein (plasma TP)	-0.39673	0.42356	-0.37703	0.624	0.356
clinical blood chemistry	triglyceride (plasma TG, no fast)	18.316	8.6786	1.1044	0.213	0.0423
EKG	duration of PQ interval	0.83289	1.0750	1.0351	0.889	0.444
EKG	duration of PR interval	0.74223	1.1306	0.85839	0.909	0.516
EKG	duration of QRS interval	-0.010527	0.27986	-0.17826	0.999	0.970
EKG	duration of QT interval	0.52286	0.86239	0.65939	0.898	0.548
EKG	duration of QTC interval, calculated by dividing QT interval by square root of preceding RR interval	0.28783	0.86251	0.37536	0.970	0.741
EKG	duration of RR interval	1.0330	1.2602	0.82112	0.793	0.418
EKG	duration of ST interval	0.48398	0.85780	0.72861	0.891	0.576
EKG	heart rate coefficient of variation (signal intensity)	0.16943	1.0507	0.22349	0.975	0.873
EKG	heart rate variability, mean of differences between sequential beats; beats per min	1.0247	7.4872	0.20906	0.974	0.892
EKG	heart rate, beats per min	-10.661	10.270	-0.93623	0.704	0.306
EKG	mean R amplitude, mean amplitude of signal measured from isoelectric line to peak of QRS	-0.018332	0.077752	-0.27255	0.940	0.815
EKG	mean SR amplitude, mean amplitude of signal measured from signal minimum line to peak of QRS	0.054262	0.10012	0.21438	0.834	0.591
EKG	number of signals	3.6387	4.8716	0.68464	0.862	0.460
EKG	proportion of number pairs of successive beat-to-beat intervals that exceed 50 ms	1.1946	4.2539	0.30156	0.973	0.780
EKG	QT dispersion, measured as inter-lead variability of QT intervals	5.2873	3.5052	1.3918	0.858	0.140
EKG	QTc dispersion, calculated as rate-corrected QT dispersion	5.2428	4.1260	1.2431	0.860	0.212
EKG	root mean square of successive differences of neighboring RR intervals	0.10965	2.1156	0.15782	0.989	0.959
glucose tolerance test	amount glucose injected	-1.5784	2.0403	-0.11922	0.776	0.447
glucose tolerance test	plasma glucose, 0min	0.72147	6.1080	-0.15436	0.958	0.907
glucose tolerance test	plasma glucose, 15min	45.190	28.982	1.3352	0.427	0.132
glucose tolerance test	plasma glucose, 30min	13.806	22.096	0.52409	0.791	0.538
glucose tolerance test	plasma glucose, 60min	25.306	11.274	1.0918	0.224	0.0343
glucose tolerance test	plasma glucose, 120min	19.138	10.452	1.1378	0.350	0.0796
grip strength	body weight (at time of grip strength test)	-0.43868	0.60854	-0.20450	0.660	0.476
grip strength	forelimb and hindlimb grip strength (mean of trials), average	1.3158	12.268	0.33434	0.957	0.915
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	0.19336	0.56901	0.46013	0.848	0.736
grip strength	forelimb and hindlimb grip strength by trial, trial1	3.5827	9.3364	0.49103	0.877	0.704
grip strength	forelimb and hindlimb grip strength by trial, trial2	5.9001	8.1967	0.62340	0.714	0.477
grip strength	forelimb and hindlimb grip strength by trial, trial3	2.1987	10.091	0.35128	0.932	0.829
grip strength	forelimb grip strength (mean of trials), average	-2.9330	5.7329	-0.10914	0.822	0.612
grip strength	forelimb grip strength (mean of trials), average normalized to bw	-10.184	13.061	-2.6019	0.703	0.441
grip strength	forelimb grip strength by trial, trial1	-3.3673	5.8873	-0.12961	0.816	0.571
grip strength	forelimb grip strength by trial, trial2	5.9636	6.1825	0.89065	0.668	0.342
grip strength	forelimb grip strength by trial, trial3	-3.2110	6.2073	-0.10038	0.832	0.608
heart weight	heart weight, normalized to body weight	-0.19242	0.10188	-1.2068	0.210	0.0675
heart weight	heart weight, weight	-3.8870	3.0309	-0.89885	0.417	0.208
hematology	basophil differential (percent of total WBC)	-0.077692	0.034102	-1.0648	0.341	0.0289
hematology	calculated hemoglobin (cHGB)	-0.054750	0.13344	-0.45309	0.843	0.684
hematology	eosinophil differential (percent of total WBC)	-0.20667	0.13960	-0.51017	0.532	0.148
hematology	hematocrit (HCT)	0.36164	0.41215	0.010934	0.648	0.386
hematology	hemoglobin concentration distribution width (HDW)	-0.054965	0.018918	-1.3929	0.0828	0.00632
hematology	large unstained cells (percent of total WBC)	0.052884	0.049659	0.36863	0.639	0.294
hematology	lymphocyte differential (percent of total WBC)	4.2318	1.6157	1.3895	0.108	0.0131
hematology	mean corpuscular hemoglobin (CHr)	0.018571	0.078353	0.18564	0.912	0.814
hematology	mean platelet volume (MPV)	0.091667	0.098989	0.43374	0.595	0.361
hematology	mean RBC corpuscular hemoglobin (MCH)	0.17503	0.094503	0.65872	0.359	0.0727
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	-0.030533	0.16123	-0.054817	0.950	0.851
hematology	mean RBC corpuscular volume (MCV)	0.56676	0.30010	0.96234	0.206	0.0673
hematology	measured hemoglobin (mHGB)	0.10994	0.12378	0.030774	0.664	0.380
hematology	monocyte differential (percent of total WBC)	-0.21833	0.097869	-0.52315	0.273	0.0322
hematology	neutrophil differential (percent of total WBC)	-3.7208	1.5525	-1.3895	0.142	0.0222
hematology	platelet count (PLT; units per volume x 10³)	-10.067	47.760	-0.084840	0.942	0.834
hematology	RBC corpuscular distribution width (RDW)	-0.41199	0.13669	-1.4441	0.0592	0.00485
hematology	RBC corpuscular hemoglobin concentration mean (CHCM)	-0.41964	0.13217	-1.1436	0.0338	0.00312
hematology	red blood cell count (RBC; per volume x 10⁶)	-0.036983	0.11513	-0.50348	0.887	0.750
hematology	reticulocyte count (Retic; units per volume x 10⁹)	-19.455	14.636	-0.75839	0.593	0.193
hematology	reticulocyte differential (percent of total RBC)	-0.18852	0.13929	-0.61869	0.543	0.185
hematology	white blood cell count (WBC; units per volume x 10³)	-0.18233	0.54418	0.056066	0.859	0.740
holeboard	number of hole pokes by individual hole number, 20 min test, 1	0.44616	0.65927	0.49652	0.831	0.502
holeboard	number of hole pokes by individual hole number, 20 min test, 2	-0.010608	0.35011	0.12609	0.990	0.976
holeboard	number of hole pokes by individual hole number, 20 min test, 3	0.74693	0.37754	1.1858	0.596	0.0530
holeboard	number of hole pokes by individual hole number, 20 min test, 4	-0.12285	0.59814	-0.032921	0.953	0.838
holeboard	number of hole pokes by individual hole number, 20 min test, 5	-0.13615	0.50289	-0.11758	0.956	0.788
holeboard	number of hole pokes by individual hole number, 20 min test, 6	-0.11885	0.25625	-0.31022	0.939	0.645
holeboard	number of hole pokes by individual hole number, 20 min test, 7	-0.19583	0.40416	-0.56935	0.958	0.630
holeboard	number of hole pokes by individual hole number, 20 min test, 8	-0.081966	0.49270	-0.039678	0.985	0.868
holeboard	number of hole pokes by individual hole number, 20 min test, 9	0.41355	0.33242	0.84114	0.686	0.219
holeboard	number of hole pokes by individual hole number, 20 min test, 10	0.026854	0.30074	0.14769	0.983	0.929
holeboard	number of hole pokes by individual hole number, 20 min test, 11	0.18058	0.24046	0.48260	0.870	0.456
holeboard	number of hole pokes by individual hole number, 20 min test, 12	0.19606	0.37699	0.44620	0.903	0.605
holeboard	number of hole pokes by individual hole number, 20 min test, 13	0.61990	0.66918	0.70769	0.750	0.358
holeboard	number of hole pokes by individual hole number, 20 min test, 14	0.52591	0.40256	0.87874	0.638	0.197
holeboard	number of hole pokes by individual hole number, 20 min test, 15	-0.10944	0.41150	-0.059073	0.919	0.791
holeboard	number of hole pokes by individual hole number, 20 min test, 16	0.56376	0.76697	0.53566	0.807	0.465
holeboard	total number of hole pokes, 20 min test	2.3892	3.3235	0.41290	0.715	0.475
light / dark	fecal boli count, 20 min test	0.75900	0.58378	0.86261	0.603	0.199
light / dark	latency to enter dark zone, 20 min test	-4.1953	51.037	-0.18355	0.978	0.935
light / dark	number of transitions between light and dark zones, 20 min test	3.2719	9.5145	0.40124	0.892	0.732
light / dark	percentage of total time in dark zone, 20 min test	6.0000	4.3274	1.2467	0.550	0.171
light / dark	percentage of total time in light zone, 20 min test	-6.0000	4.3274	-1.2526	0.551	0.171
light / dark	time mobile in dark zone, 20 min test	-6.2686	13.769	-0.51851	0.846	0.651
light / dark	time mobile in light zone, 20 min test	-11.771	11.726	-1.0625	0.585	0.320
light / dark	time spent in dark zone, 20 min test	50.570	54.189	0.98265	0.734	0.355
light / dark	time spent in light zone, 20 min test	-50.570	54.189	-0.98265	0.734	0.355
open field	average speed in center of arena, 20 min test	0.17692	0.33172	0.21856	0.829	0.596
open field	average speed in periphery of arena, 20 min test	0.24060	0.15772	0.40048	0.320	0.134
open field	distance traveled habituation ratio, 20 min test	6.9585	9.4964	0.58405	0.739	0.468
open field	distance traveled in center of arena, 20 min test	36.663	107.75	-0.16250	0.861	0.735
open field	distance traveled in periphery of arena, 20 min test	233.86	139.60	0.46686	0.288	0.101
open field	distance traveled slope, 20 min test	8.5352	9.5396	0.76992	0.688	0.376
open field	distance traveled, 20 min test, 1st 5min	98.897	69.336	0.45641	0.377	0.161
open field	distance traveled, 20 min test, 2nd 5min	22.741	55.293	-0.23095	0.837	0.683
open field	distance traveled, 20 min test, 3rd 5min	53.921	60.639	0.15706	0.633	0.379
open field	distance traveled, 20 min test, 4th 5min	109.15	74.109	0.71508	0.362	0.148
open field	number of clockwise revolution episodes, 20 min test	0.71445	1.1431	0.012090	0.804	0.535
open field	number of counter-clockwise revolution episodes, 20 min test	1.4625	1.1017	0.34577	0.474	0.191
open field	number of fecal boli, 20 min test	-0.70616	0.80783	-0.28600	0.689	0.387
open field	number of rears in 5 min bins, 20 min test, 1st 5min	1.9038	1.6138	0.32253	0.509	0.244
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	-3.7071	1.9111	-1.2655	0.257	0.0588
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	-4.3441	2.4220	-1.3023	0.284	0.0797
open field	number of rears in 5 min bins, 20 min test, 4th 5min	1.4418	2.5697	-0.032900	0.782	0.578
open field	percentage of total time in center of arena, 20 min test	-1.3903	2.8354	-0.54937	0.852	0.626
open field	percentage of total time in center of arena, slope, 20 min test	0.37722	1.4542	0.32730	0.955	0.797
open field	percentage of total time in center, habituation ratio, 20 min test	0.64282	1.4729	0.45641	0.901	0.665
open field	percentage of total time in corners of arena, 20 min test	1.2641	4.5048	0.52918	0.916	0.780
open field	percentage of total time in corners, habituation ratio, 20 min test	-3.5878	2.0242	-1.8654	0.534	0.0832
open field	percentage of total time in corners, slope, 20 min test	-3.3711	1.9869	-1.8074	0.565	0.0968
open field	permanence time in center of arena, 20 min test	-16.678	34.025	-0.54625	0.853	0.627
open field	permanence time in corners of arena, 20 min test	15.162	54.056	0.52918	0.917	0.780
open field	permanence time in periphery of arena, 20 min test	16.682	34.029	0.54781	0.853	0.626
open field	total distance traveled, 20 min test	260.51	211.95	0.26001	0.435	0.226
open field	total number of rears, 20 min test	-5.0471	6.8640	-0.67407	0.699	0.466
open field	whole arena average speed, 20 min test	0.21800	0.17649	0.26001	0.433	0.223
open field	whole arena resting time, 20 min test	-32.104	21.400	-0.33866	0.310	0.141
open field	whole arena time spent mobile, 20 min test	32.010	21.406	0.58883	0.318	0.142
open field	whole arena time spent vertical, 20 min test	-9.6711	6.0825	-0.87539	0.386	0.119
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	-0.98899	1.7869	-0.21910	0.816	0.584
startle / PPI	average baseline movement during background noise	-3.1389	1.3049	-2.0179	0.421	0.0205
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	0.028639	0.057313	0.14553	0.831	0.620
startle / PPI	average of each corrected percent pre-pulse inhibition value	0.053305	0.058306	0.45964	0.703	0.366
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	7.4836	7.3610	0.86950	0.879	0.315
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	5.2621	6.5598	0.47471	0.737	0.427
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	3.8364	5.5651	0.30082	0.763	0.494
startle / PPI	average startle response to full pulse (120 dB)	-36.180	37.721	-0.49837	0.593	0.343
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-52.917	40.415	-0.78658	0.426	0.197
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-45.283	36.099	-0.70336	0.433	0.217
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-34.857	30.691	-0.62815	0.481	0.262
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	-2.4917	1.1002	-1.6528	0.492	0.0287
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	0.079986	1.6897	0.087683	0.993	0.962
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	-1.7544	1.9820	-1.0916	0.766	0.381
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.077095	0.080162	0.77518	0.869	0.342
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.057313	0.069696	0.39964	0.713	0.415
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.025508	0.067065	0.044876	0.875	0.706
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	-33.712	37.826	-0.44977	0.619	0.378
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	-49.886	40.507	-0.72688	0.457	0.225
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	-45.101	36.216	-0.69620	0.434	0.220
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	-32.279	31.019	-0.55634	0.518	0.304
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.066034	0.075442	0.62134	0.860	0.386
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.018678	0.068323	0.042070	0.910	0.786
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.0012044	0.069267	-0.17899	0.996	0.986
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	-169.45	144.17	-0.64531	0.486	0.246
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	-222.97	155.26	-0.91116	0.373	0.158
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	-158.20	133.98	-0.65744	0.458	0.244
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	-121.77	120.53	-0.55962	0.532	0.318
startle / PPI	maximum baseline movement during background noise	-6.8349	3.2605	-1.7478	0.463	0.0420
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	6.5224	7.2535	0.68730	0.890	0.374
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	1.5310	6.5768	0.052567	0.932	0.817
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	1.0254	6.1626	-0.055373	0.947	0.869
startle / PPI	maximum startle response to full pulse (120 dB)	-174.87	144.02	-0.66092	0.466	0.231
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-229.50	155.08	-0.95004	0.355	0.146
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-158.20	133.52	-0.65744	0.458	0.243
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-127.87	119.65	-0.61117	0.512	0.291
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	-5.8977	2.6044	-1.5022	0.465	0.0286
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	0.95760	3.9943	0.29788	0.972	0.812
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	-3.8521	4.9005	-0.98586	0.789	0.436

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

In this plot, data points are the computed genotype effect % vs. C57BL/6NJ controls, for all measured categorical phenotypes in JaxKOMP-EAP

Dimensions Width: × Height: px

Plot Options Group by Procedure

Include Sexes Data Both Females Males

Significance Threshold p-Value Threshold

Download Plot

Procedure	JaxKOMP-EAP Trait	Sex	Trait Effect	P-value

eye morphology	anterior chamber depth	females	1.0 %	1.0
eye morphology	anterior chamber depth	males	0.0 %	1.0
eye morphology	anterior chamber depth	both	1.0 %	1.0
eye morphology	bulging eye	females	1.0 %	1.0
eye morphology	bulging eye	males	0.0 %	1.0
eye morphology	bulging eye	both	1.0 %	1.00
eye morphology	cornea	females	4.0 %	1.0
eye morphology	cornea	males	2.0 %	1.0
eye morphology	cornea	both	3.0 %	1.00
eye morphology	cornea opacity	females	5.0 %	1.00
eye morphology	cornea opacity	males	1.0 %	1.0
eye morphology	cornea opacity	both	3.0 %	1.00
eye morphology	cornea vascularization	females	3.0 %	1.0
eye morphology	cornea vascularization	males	1.0 %	1.0
eye morphology	cornea vascularization	both	2.0 %	1.00
eye morphology	corneal deposits	females	2.0 %	1.0
eye morphology	corneal deposits	males	1.0 %	1.0
eye morphology	corneal deposits	both	1.0 %	1.00
eye morphology	corneal mineralization	females	2.0 %	1.0
eye morphology	corneal mineralization	males	1.0 %	1.0
eye morphology	corneal mineralization	both	1.0 %	1.00
eye morphology	corneal scleralization	females	3.0 %	1.00
eye morphology	corneal scleralization	males	1.0 %	1.0
eye morphology	corneal scleralization	both	2.0 %	1.00
eye morphology	corneal ulcer	females	1.0 %	1.0
eye morphology	corneal ulcer	males	1.0 %	1.0
eye morphology	corneal ulcer	both	1.0 %	1.00
eye morphology	eye closure	females	1.0 %	1.00
eye morphology	eye closure	males	0.0 %	1.0
eye morphology	eye closure	both	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	females	12.0 %	0.0696
eye morphology	eye hemorrhage or blood presence	males	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	both	6.0 %	0.0885
eye morphology	eyelid morphology	females	1.0 %	1.0
eye morphology	eyelid morphology	males	0.0 %	1.0
eye morphology	eyelid morphology	both	1.0 %	1.0
eye morphology	eyes (present, absent)	females	1.0 %	1.0
eye morphology	eyes (present, absent)	males	0.0 %	1.0
eye morphology	eyes (present, absent)	both	0.0 %	1.0
eye morphology	fusion between cornea and lens	females	4.0 %	1.00
eye morphology	fusion between cornea and lens	males	2.0 %	1.0
eye morphology	fusion between cornea and lens	both	3.0 %	1.00
eye morphology	iris pigmentation	females	2.0 %	1.0
eye morphology	iris pigmentation	males	1.0 %	1.0
eye morphology	iris pigmentation	both	2.0 %	1.00
eye morphology	iris transillumination	females	2.0 %	1.00
eye morphology	iris transillumination	males	1.0 %	1.0
eye morphology	iris transillumination	both	1.0 %	1.00
eye morphology	irispupil	females	4.0 %	1.00
eye morphology	irispupil	males	3.0 %	1.0
eye morphology	irispupil	both	3.0 %	1.00
eye morphology	lacrimation	females	3.0 %	1.0
eye morphology	lacrimation	males	12.0 %	0.0846
eye morphology	lacrimation	both	6.0 %	0.180
eye morphology	lens	females	10.0 %	1.00
eye morphology	lens	males	8.0 %	1.0
eye morphology	lens	both	9.0 %	1.0
eye morphology	lens opacity	females	23.0 %	0.0557
eye morphology	lens opacity	males	57.0 %	0.0000338
eye morphology	lens opacity	both	36.0 %	0.0000580
eye morphology	narrow eye opening	females	2.0 %	1.0
eye morphology	narrow eye opening	males	1.0 %	1.0
eye morphology	narrow eye opening	both	1.0 %	1.0
eye morphology	optic disc	females	4.0 %	1.00
eye morphology	optic disc	males	2.0 %	1.0
eye morphology	optic disc	both	3.0 %	1.00
eye morphology	persistence of hyaloid vascular system	females	18.0 %	0.373
eye morphology	persistence of hyaloid vascular system	males	5.0 %	1.0
eye morphology	persistence of hyaloid vascular system	both	8.0 %	0.504
eye morphology	pupil dilation	females	2.0 %	1.0
eye morphology	pupil dilation	males	1.0 %	1.0
eye morphology	pupil dilation	both	2.0 %	1.0
eye morphology	pupil light response	females	2.0 %	1.00
eye morphology	pupil light response	males	1.0 %	1.0
eye morphology	pupil light response	both	2.0 %	1.00
eye morphology	pupil position	females	4.0 %	1.00
eye morphology	pupil position	males	3.0 %	1.0
eye morphology	pupil position	both	4.0 %	1.00
eye morphology	pupil shape	females	3.0 %	1.00
eye morphology	pupil shape	males	2.0 %	1.0
eye morphology	pupil shape	both	3.0 %	1.00
eye morphology	retina	females	10.0 %	1.0
eye morphology	retina	males	20.0 %	0.220
eye morphology	retina	both	9.0 %	0.503
eye morphology	retinal blood vessels	females	4.0 %	1.0
eye morphology	retinal blood vessels	males	2.0 %	1.0
eye morphology	retinal blood vessels	both	3.0 %	1.0
eye morphology	retinal blood vessels pattern	females	5.0 %	1.0
eye morphology	retinal blood vessels pattern	males	2.0 %	1.0
eye morphology	retinal blood vessels pattern	both	4.0 %	1.00
eye morphology	retinal blood vessels structure	females	4.0 %	1.00
eye morphology	retinal blood vessels structure	males	2.0 %	1.0
eye morphology	retinal blood vessels structure	both	3.0 %	1.00
eye morphology	retinal pigmentation	females	10.0 %	0.522
eye morphology	retinal pigmentation	males	14.0 %	1.0
eye morphology	retinal pigmentation	both	7.0 %	0.794
eye morphology	retinal structure	females	4.0 %	1.00
eye morphology	retinal structure	males	2.0 %	1.0
eye morphology	retinal structure	both	3.0 %	1.00
eye morphology	synechia	females	4.0 %	1.0
eye morphology	synechia	males	2.0 %	1.0
eye morphology	synechia	both	3.0 %	1.00
eye morphology	vitreous	females	4.0 %	1.00
eye morphology	vitreous	males	2.0 %	1.0
eye morphology	vitreous	both	3.0 %	1.00
SHIRPA	activity body position	females	1.0 %	1.0
SHIRPA	activity body position	males	2.0 %	1.0
SHIRPA	activity body position	both	1.0 %	1.00
SHIRPA	aggression	females	0.0 %	1.00
SHIRPA	aggression	males	1.0 %	1.0
SHIRPA	aggression	both	1.0 %	1.0
SHIRPA	body length	females	0.0 %	1.00
SHIRPA	body length	males	0.0 %	1.0
SHIRPA	body length	both	0.0 %	1.00
SHIRPA	body position	females	0.0 %	1.00
SHIRPA	body position	males	1.0 %	1.0
SHIRPA	body position	both	0.0 %	1.0
SHIRPA	body thickness	females	1.0 %	1.0
SHIRPA	body thickness	males	0.0 %	1.0
SHIRPA	body thickness	both	0.0 %	1.0
SHIRPA	coat color abdomen	females	3.0 %	1.00
SHIRPA	coat color abdomen	males	4.0 %	1.0
SHIRPA	coat color abdomen	both	4.0 %	1.0
SHIRPA	coat color back	females	0.0 %	1.0
SHIRPA	coat color back	males	0.0 %	1.00
SHIRPA	coat color back	both	0.0 %	1.0
SHIRPA	coat color head	females	0.0 %	1.0
SHIRPA	coat color head	males	0.0 %	1.00
SHIRPA	coat color head	both	0.0 %	1.0
SHIRPA	coat color pattern abdomen	females	1.0 %	1.0
SHIRPA	coat color pattern abdomen	males	1.0 %	1.0
SHIRPA	coat color pattern abdomen	both	1.0 %	1.0
SHIRPA	coat color pattern back	females	0.0 %	1.00
SHIRPA	coat color pattern back	males	0.0 %	1.00
SHIRPA	coat color pattern back	both	0.0 %	1.0
SHIRPA	coat color pattern head	females	0.0 %	1.0
SHIRPA	coat color pattern head	males	0.0 %	1.0
SHIRPA	coat color pattern head	both	0.0 %	1.00
SHIRPA	coat hair abdomen texture appearance	females	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	males	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	both	2.0 %	1.0
SHIRPA	coat hair back texture appearance	females	0.0 %	1.0
SHIRPA	coat hair back texture appearance	males	0.0 %	1.0
SHIRPA	coat hair back texture appearance	both	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	females	0.0 %	1.00
SHIRPA	coat hair distribution abdomen	males	1.0 %	1.0
SHIRPA	coat hair distribution abdomen	both	1.0 %	1.0
SHIRPA	coat hair distribution back	females	0.0 %	1.00
SHIRPA	coat hair distribution back	males	0.0 %	1.0
SHIRPA	coat hair distribution back	both	0.0 %	1.00
SHIRPA	coat hair distribution head	females	1.0 %	1.00
SHIRPA	coat hair distribution head	males	1.0 %	1.0
SHIRPA	coat hair distribution head	both	1.0 %	1.0
SHIRPA	coat hair head texture appearance	females	0.0 %	1.0
SHIRPA	coat hair head texture appearance	males	0.0 %	1.0
SHIRPA	coat hair head texture appearance	both	0.0 %	1.0
SHIRPA	contact righting	females	5.0 %	1.0
SHIRPA	contact righting	males	5.0 %	1.0
SHIRPA	contact righting	both	5.0 %	1.0
SHIRPA	ear morphology	females	0.0 %	1.0
SHIRPA	ear morphology	males	0.0 %	1.0
SHIRPA	ear morphology	both	0.0 %	1.0
SHIRPA	fat distribution	females	0.0 %	1.0
SHIRPA	fat distribution	males	0.0 %	1.0
SHIRPA	fat distribution	both	0.0 %	1.0
SHIRPA	forelimb digit number	females	0.0 %	1.0
SHIRPA	forelimb digit number	males	0.0 %	1.0
SHIRPA	forelimb digit number	both	0.0 %	1.0
SHIRPA	forelimb digit position	females	0.0 %	1.0
SHIRPA	forelimb digit position	males	0.0 %	1.0
SHIRPA	forelimb digit position	both	0.0 %	1.0
SHIRPA	forelimb digit shape	females	0.0 %	1.0
SHIRPA	forelimb digit shape	males	0.0 %	1.0
SHIRPA	forelimb digit shape	both	0.0 %	1.0
SHIRPA	forelimb digit size	females	0.0 %	1.0
SHIRPA	forelimb digit size	males	0.0 %	1.0
SHIRPA	forelimb digit size	both	0.0 %	1.0
SHIRPA	forelimb footpads	females	0.0 %	1.0
SHIRPA	forelimb footpads	males	0.0 %	1.0
SHIRPA	forelimb footpads	both	0.0 %	1.0
SHIRPA	forelimb nail length	females	0.0 %	1.0
SHIRPA	forelimb nail length	males	0.0 %	1.0
SHIRPA	forelimb nail length	both	0.0 %	1.0
SHIRPA	forelimb nail number	females	0.0 %	1.0
SHIRPA	forelimb nail number	males	0.0 %	1.0
SHIRPA	forelimb nail number	both	0.0 %	1.0
SHIRPA	forelimb nail position	females	0.0 %	1.0
SHIRPA	forelimb nail position	males	0.0 %	1.0
SHIRPA	forelimb nail position	both	0.0 %	1.0
SHIRPA	forelimb nail shape	females	0.0 %	1.0
SHIRPA	forelimb nail shape	males	0.0 %	1.0
SHIRPA	forelimb nail shape	both	0.0 %	1.0
SHIRPA	forelimbs position	females	0.0 %	1.0
SHIRPA	forelimbs position	males	0.0 %	1.0
SHIRPA	forelimbs position	both	0.0 %	1.0
SHIRPA	forelimbs shape	females	0.0 %	1.0
SHIRPA	forelimbs shape	males	0.0 %	1.0
SHIRPA	forelimbs shape	both	0.0 %	1.0
SHIRPA	forelimbs size	females	0.0 %	1.00
SHIRPA	forelimbs size	males	0.0 %	1.0
SHIRPA	forelimbs size	both	0.0 %	1.0
SHIRPA	forepaw position	females	0.0 %	1.0
SHIRPA	forepaw position	males	0.0 %	1.0
SHIRPA	forepaw position	both	0.0 %	1.0
SHIRPA	forepaw shape	females	0.0 %	1.0
SHIRPA	forepaw shape	males	0.0 %	1.0
SHIRPA	forepaw shape	both	0.0 %	1.0
SHIRPA	forepaw size	females	0.0 %	1.0
SHIRPA	forepaw size	males	0.0 %	1.0
SHIRPA	forepaw size	both	0.0 %	1.0
SHIRPA	gait (fluidity)	females	0.0 %	1.0
SHIRPA	gait (fluidity)	males	0.0 %	1.0
SHIRPA	gait (fluidity)	both	0.0 %	1.0
SHIRPA	genitalia morphology	females	0.0 %	1.0
SHIRPA	genitalia morphology	males	0.0 %	1.0
SHIRPA	genitalia morphology	both	0.0 %	1.0
SHIRPA	genitalia presence	females	0.0 %	1.0
SHIRPA	genitalia presence	males	0.0 %	1.0
SHIRPA	genitalia presence	both	0.0 %	1.0
SHIRPA	genitalia size	females	0.0 %	1.0
SHIRPA	genitalia size	males	0.0 %	1.0
SHIRPA	genitalia size	both	0.0 %	1.0
SHIRPA	head bobbing	females	0.0 %	1.0
SHIRPA	head bobbing	males	0.0 %	1.0
SHIRPA	head bobbing	both	0.0 %	1.0
SHIRPA	head morphology	females	0.0 %	1.0
SHIRPA	head morphology	males	0.0 %	1.0
SHIRPA	head morphology	both	0.0 %	1.0
SHIRPA	head size	females	0.0 %	1.0
SHIRPA	head size	males	0.0 %	1.0
SHIRPA	head size	both	0.0 %	1.0
SHIRPA	hindlimb digit number	females	1.0 %	1.0
SHIRPA	hindlimb digit number	males	0.0 %	1.0
SHIRPA	hindlimb digit number	both	0.0 %	1.0
SHIRPA	hindlimb digit position	females	0.0 %	1.0
SHIRPA	hindlimb digit position	males	0.0 %	1.0
SHIRPA	hindlimb digit position	both	0.0 %	1.0
SHIRPA	hindlimb digit shape	females	0.0 %	1.00
SHIRPA	hindlimb digit shape	males	0.0 %	1.0
SHIRPA	hindlimb digit shape	both	0.0 %	1.00
SHIRPA	hindlimb digit size	females	0.0 %	1.0
SHIRPA	hindlimb digit size	males	0.0 %	1.0
SHIRPA	hindlimb digit size	both	0.0 %	1.0
SHIRPA	hindlimb nail length	females	0.0 %	1.0
SHIRPA	hindlimb nail length	males	0.0 %	1.0
SHIRPA	hindlimb nail length	both	0.0 %	1.0
SHIRPA	hindlimb nail number	females	0.0 %	1.0
SHIRPA	hindlimb nail number	males	1.0 %	1.0
SHIRPA	hindlimb nail number	both	0.0 %	1.0
SHIRPA	hindlimb nail position	females	0.0 %	1.0
SHIRPA	hindlimb nail position	males	0.0 %	1.0
SHIRPA	hindlimb nail position	both	0.0 %	1.0
SHIRPA	hindlimb nail shape	females	0.0 %	1.0
SHIRPA	hindlimb nail shape	males	0.0 %	1.0
SHIRPA	hindlimb nail shape	both	0.0 %	1.0
SHIRPA	hindlimbs footpads	females	0.0 %	1.0
SHIRPA	hindlimbs footpads	males	0.0 %	1.0
SHIRPA	hindlimbs footpads	both	0.0 %	1.0
SHIRPA	hindlimbs position	females	0.0 %	1.0
SHIRPA	hindlimbs position	males	0.0 %	1.0
SHIRPA	hindlimbs position	both	0.0 %	1.0
SHIRPA	hindlimbs shape	females	0.0 %	1.0
SHIRPA	hindlimbs shape	males	0.0 %	1.0
SHIRPA	hindlimbs shape	both	0.0 %	1.0
SHIRPA	hindlimbs size	females	0.0 %	1.0
SHIRPA	hindlimbs size	males	0.0 %	1.0
SHIRPA	hindlimbs size	both	0.0 %	1.0
SHIRPA	hindpaw position	females	0.0 %	1.0
SHIRPA	hindpaw position	males	0.0 %	1.0
SHIRPA	hindpaw position	both	0.0 %	1.0
SHIRPA	hindpaw shape	females	0.0 %	1.0
SHIRPA	hindpaw shape	males	0.0 %	1.0
SHIRPA	hindpaw shape	both	0.0 %	1.0
SHIRPA	hindpaw size	females	0.0 %	1.0
SHIRPA	hindpaw size	males	0.0 %	1.0
SHIRPA	hindpaw size	both	0.0 %	1.0
SHIRPA	limb grasp	females	11.0 %	0.371
SHIRPA	limb grasp	males	6.0 %	1.0
SHIRPA	limb grasp	both	2.0 %	0.565
SHIRPA	lower lip morphology	females	0.0 %	1.0
SHIRPA	lower lip morphology	males	0.0 %	1.0
SHIRPA	lower lip morphology	both	0.0 %	1.0
SHIRPA	lower teeth appearance	females	0.0 %	1.0
SHIRPA	lower teeth appearance	males	0.0 %	1.00
SHIRPA	lower teeth appearance	both	0.0 %	1.00
SHIRPA	mouth morphology	females	0.0 %	1.0
SHIRPA	mouth morphology	males	0.0 %	1.0
SHIRPA	mouth morphology	both	0.0 %	1.0
SHIRPA	salivation	females	0.0 %	1.0
SHIRPA	salivation	males	0.0 %	1.0
SHIRPA	salivation	both	0.0 %	1.0
SHIRPA	skin color back paws	females	0.0 %	1.0
SHIRPA	skin color back paws	males	0.0 %	1.0
SHIRPA	skin color back paws	both	0.0 %	1.0
SHIRPA	skin color ear	females	0.0 %	1.0
SHIRPA	skin color ear	males	0.0 %	1.0
SHIRPA	skin color ear	both	0.0 %	1.0
SHIRPA	skin color front paws	females	0.0 %	1.0
SHIRPA	skin color front paws	males	0.0 %	1.0
SHIRPA	skin color front paws	both	0.0 %	1.0
SHIRPA	skin color snout	females	0.0 %	1.0
SHIRPA	skin color snout	males	0.0 %	1.0
SHIRPA	skin color snout	both	0.0 %	1.0
SHIRPA	skin color tail	females	0.0 %	1.0
SHIRPA	skin color tail	males	0.0 %	1.0
SHIRPA	skin color tail	both	0.0 %	1.0
SHIRPA	skin color whole body	females	0.0 %	1.0
SHIRPA	skin color whole body	males	0.0 %	1.0
SHIRPA	skin color whole body	both	0.0 %	1.0
SHIRPA	skin texture back paw	females	0.0 %	1.0
SHIRPA	skin texture back paw	males	0.0 %	1.0
SHIRPA	skin texture back paw	both	0.0 %	1.0
SHIRPA	skin texture ear	females	0.0 %	1.0
SHIRPA	skin texture ear	males	0.0 %	1.0
SHIRPA	skin texture ear	both	0.0 %	1.0
SHIRPA	skin texture front paws	females	0.0 %	1.0
SHIRPA	skin texture front paws	males	0.0 %	1.0
SHIRPA	skin texture front paws	both	0.0 %	1.0
SHIRPA	skin texture snout	females	0.0 %	1.0
SHIRPA	skin texture snout	males	0.0 %	1.0
SHIRPA	skin texture snout	both	0.0 %	1.0
SHIRPA	skin texture tail	females	0.0 %	1.0
SHIRPA	skin texture tail	males	0.0 %	1.0
SHIRPA	skin texture tail	both	0.0 %	1.0
SHIRPA	skin texture whole body	females	0.0 %	1.0
SHIRPA	skin texture whole body	males	0.0 %	1.0
SHIRPA	skin texture whole body	both	0.0 %	1.0
SHIRPA	snout size	females	0.0 %	1.00
SHIRPA	snout size	males	1.0 %	1.00
SHIRPA	snout size	both	0.0 %	1.0
SHIRPA	startle response	females	0.0 %	1.00
SHIRPA	startle response	males	0.0 %	1.00
SHIRPA	startle response	both	0.0 %	1.0
SHIRPA	tail curvature	females	0.0 %	1.0
SHIRPA	tail curvature	males	0.0 %	1.0
SHIRPA	tail curvature	both	0.0 %	1.00
SHIRPA	tail elevation	females	19.0 %	0.0469
SHIRPA	tail elevation	males	2.0 %	1.0
SHIRPA	tail elevation	both	8.0 %	0.144
SHIRPA	tail length	females	0.0 %	1.0
SHIRPA	tail length	males	0.0 %	1.0
SHIRPA	tail length	both	0.0 %	1.00
SHIRPA	tail morphology	females	0.0 %	1.00
SHIRPA	tail morphology	males	0.0 %	1.0
SHIRPA	tail morphology	both	0.0 %	1.0
SHIRPA	tail presence	females	0.0 %	1.0
SHIRPA	tail presence	males	0.0 %	1.0
SHIRPA	tail presence	both	0.0 %	1.0
SHIRPA	tail shape	females	0.0 %	1.0
SHIRPA	tail shape	males	0.0 %	1.0
SHIRPA	tail shape	both	0.0 %	1.00
SHIRPA	tail thickness	females	0.0 %	1.0
SHIRPA	tail thickness	males	0.0 %	1.0
SHIRPA	tail thickness	both	0.0 %	1.0
SHIRPA	teeth presence	females	0.0 %	1.0
SHIRPA	teeth presence	males	0.0 %	1.0
SHIRPA	teeth presence	both	0.0 %	1.00
SHIRPA	transfer arousal	females	1.0 %	1.0
SHIRPA	transfer arousal	males	2.0 %	1.0
SHIRPA	transfer arousal	both	1.0 %	1.0
SHIRPA	tremor	females	0.0 %	1.00
SHIRPA	tremor	males	0.0 %	1.00
SHIRPA	tremor	both	0.0 %	1.0
SHIRPA	trunk curl	females	0.0 %	1.00
SHIRPA	trunk curl	males	0.0 %	1.0
SHIRPA	trunk curl	both	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	females	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	males	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	both	0.0 %	1.0
SHIRPA	upper lip morphology	females	0.0 %	1.0
SHIRPA	upper lip morphology	males	0.0 %	1.0
SHIRPA	upper lip morphology	both	0.0 %	1.0
SHIRPA	upper teeth appearance	females	0.0 %	1.0
SHIRPA	upper teeth appearance	males	0.0 %	1.0
SHIRPA	upper teeth appearance	both	0.0 %	1.00
SHIRPA	vibrissae appearance	females	2.0 %	1.0
SHIRPA	vibrissae appearance	males	1.0 %	1.0
SHIRPA	vibrissae appearance	both	1.0 %	1.0
SHIRPA	vibrissae presence	females	2.0 %	1.0
SHIRPA	vibrissae presence	males	1.0 %	1.0
SHIRPA	vibrissae presence	both	2.0 %	1.0
SHIRPA	vocalization	females	2.0 %	1.0
SHIRPA	vocalization	males	2.0 %	1.0
SHIRPA	vocalization	both	2.0 %	1.0

GENOTYPE CORRELATION PLOT

Correlate Mylk4^em1(IMPC)J/Mmjax -/- with genotype: