MPD: JaxKOMP-EAP genotype: Gsto1<sup>em1(IMPC)J</sup>/Mmjax -/-

JaxKOMP-EAP effect sizes: Gsto1^em1(IMPC)J/Mmjax -/- Gene Gsto1

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

In this plot, data points are the computed genotype effect size vs. C57BL/6NJ controls, for all measured numeric phenotypes in JaxKOMP-EAP

Dimensions Width: × Height: px

Plot Options Group by Procedure Standard Error Show Effect Sizes RankZ

Significance Threshold p-Value Threshold Adjusted Unadjusted

Download Plot

Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value

ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	-5.1582	3.6133	-1.0569	0.698	0.213
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	-0.078368	1.8267	-0.19653	0.994	0.967
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	1.5862	9.3539	0.13482	0.952	0.872
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	-3.4807	10.208	-0.56901	0.898	0.747
body composition	body length	-0.026411	0.041753	-0.10527	0.778	0.530
body composition	body weight (at time of DXA)	0.78025	0.57045	0.73439	0.383	0.177
body composition	bone area, whole body scan, head excluded	-0.38121	0.14634	-1.2064	0.0880	0.0121
body composition	bone mineral content of whole body scan, head excluded	-0.025303	0.010867	-1.1464	0.142	0.0241
body composition	bone mineral content to body weight ratio	-0.00093490	0.00036008	-0.98501	0.0891	0.0124
body composition	bone mineral density of whole body scan, head excluded	-0.00054234	0.00055916	-0.58090	0.636	0.337
body composition	fat tissue mass of whole body scan, head excluded	0.87253	0.34748	1.2322	0.107	0.0154
body composition	fat tissue mass to body weight ratio	0.030179	0.012182	1.2559	0.0969	0.0167
body composition	lean tissue mass of whole body scan, head excluded	-0.49048	0.42902	-1.1333	0.555	0.258
body composition	lean tissue mass to body weight ratio	-0.021323	0.011927	-1.1593	0.270	0.0800
body composition	percent fat, whole body scan, head excluded	2.8237	1.1945	1.2834	0.119	0.0221
body composition	ratio of soft-tissue attenuation coefficients	-0.0031360	0.0013273	-1.2822	0.119	0.0222
body composition	tissue area	0.046905	0.21369	0.33992	0.945	0.827
body composition	total tissue mass, whole body scan, head excluded	0.33507	0.32024	0.50383	0.556	0.301
clinical blood chemistry	alanine transaminase (plasma ALT)	-3.1256	4.4340	-0.30878	0.794	0.486
clinical blood chemistry	albumin (plasma Alb)	0.23174	0.39590	0.37199	0.824	0.563
clinical blood chemistry	alkaline phosphatase (plasma ALP)	-0.71109	5.4330	-0.64498	0.953	0.897
clinical blood chemistry	aspartate transaminase (plasma AST)	-3.5355	13.620	-0.17672	0.939	0.797
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	-0.15474	0.36072	-0.49018	0.897	0.671
clinical blood chemistry	blood urea nitrogen (BUN)	-4.2816	1.3162	-1.5403	0.0398	0.00276
clinical blood chemistry	calcium (plasma Ca)	-0.054835	0.075746	-0.037687	0.694	0.474
clinical blood chemistry	creatinine (plasma)	-0.10786	0.034975	-1.7906	0.0442	0.00427
clinical blood chemistry	glucose (plasma GLU, no fast)	-24.078	12.139	-0.59883	0.170	0.0559
clinical blood chemistry	HDL cholesterol (plasma HDL)	2.1756	2.6443	0.18742	0.700	0.417
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	0.0042518	0.013108	0.10052	0.922	0.748
clinical blood chemistry	phosphorus (plasma phosphate)	-0.73125	0.37157	-1.1781	0.245	0.0578
clinical blood chemistry	total bilirubin (plasma TBIL)	-0.0069959	0.013421	-0.53387	0.838	0.606
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	3.2091	2.8152	0.34135	0.584	0.263
clinical blood chemistry	total protein (plasma TP)	0.98520	0.78181	0.69434	0.499	0.217
clinical blood chemistry	triglyceride (plasma TG, no fast)	-5.4280	12.548	-0.077336	0.846	0.668
EKG	duration of PQ interval	-0.13584	0.77965	0.0040300	0.971	0.863
EKG	duration of PR interval	-0.45151	0.86230	-0.36672	0.934	0.603
EKG	duration of QRS interval	-0.11776	0.32933	-0.46788	0.967	0.723
EKG	duration of QT interval	1.4396	0.95731	1.4644	0.649	0.140
EKG	duration of QTC interval, calculated by dividing QT interval by square root of preceding RR interval	0.88337	1.0133	0.97820	0.878	0.389
EKG	duration of RR interval	2.3448	1.2966	1.3760	0.448	0.0781
EKG	duration of ST interval	1.5439	0.87739	1.7302	0.569	0.0861
EKG	heart rate coefficient of variation (signal intensity)	0.27583	1.0519	0.31970	0.968	0.794
EKG	heart rate variability, mean of differences between sequential beats; beats per min	1.0731	7.7689	0.21112	0.974	0.891
EKG	heart rate, beats per min	-20.921	11.164	-1.5256	0.392	0.0683
EKG	mean R amplitude, mean amplitude of signal measured from isoelectric line to peak of QRS	0.010691	0.10587	-0.039334	0.972	0.920
EKG	mean SR amplitude, mean amplitude of signal measured from signal minimum line to peak of QRS	-0.0097560	0.14765	-0.12231	0.981	0.948
EKG	number of signals	0.72919	5.4688	0.12729	0.981	0.895
EKG	proportion of number pairs of successive beat-to-beat intervals that exceed 50 ms	3.3938	4.2093	0.72650	0.855	0.425
EKG	QT dispersion, measured as inter-lead variability of QT intervals	-0.32503	2.4657	-0.060486	0.989	0.896
EKG	QTc dispersion, calculated as rate-corrected QT dispersion	-1.6824	2.6835	-0.44107	0.931	0.534
EKG	root mean square of successive differences of neighboring RR intervals	-0.19069	1.9138	0.010075	0.979	0.921
glucose tolerance test	amount glucose injected	6.6756	2.7486	1.7829	0.207	0.0199
glucose tolerance test	plasma glucose, 0min	4.2244	3.9493	0.19898	0.509	0.291
glucose tolerance test	plasma glucose, 15min	-17.651	22.908	-0.37661	0.743	0.446
glucose tolerance test	plasma glucose, 30min	15.204	22.688	0.57356	0.774	0.507
glucose tolerance test	plasma glucose, 60min	36.831	16.399	1.4751	0.215	0.0303
glucose tolerance test	plasma glucose, 120min	15.135	8.0460	0.89814	0.327	0.0673
grip strength	body weight (at time of grip strength test)	0.12925	0.50054	0.32169	0.886	0.798
grip strength	forelimb and hindlimb grip strength (mean of trials), average	-26.162	9.2108	-1.5526	0.0459	0.00756
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	-0.98542	0.42050	-1.2078	0.104	0.0251
grip strength	forelimb and hindlimb grip strength by trial, trial1	-23.722	10.640	-1.3208	0.181	0.0323
grip strength	forelimb and hindlimb grip strength by trial, trial2	-31.458	10.186	-1.7119	0.0458	0.00393
grip strength	forelimb and hindlimb grip strength by trial, trial3	-19.309	11.138	-0.99484	0.306	0.0920
grip strength	forelimb grip strength (mean of trials), average	-12.550	4.4334	-1.2354	0.0645	0.00774
grip strength	forelimb grip strength (mean of trials), average normalized to bw	-0.41328	0.21728	-0.81542	0.248	0.0657
grip strength	forelimb grip strength by trial, trial1	-13.369	5.0823	-1.2078	0.141	0.0126
grip strength	forelimb grip strength by trial, trial2	-10.604	5.2208	-0.91466	0.272	0.0499
grip strength	forelimb grip strength by trial, trial3	-11.912	5.5723	-1.0092	0.224	0.0398
heart weight	heart weight, normalized to body weight	-0.076367	0.11494	-0.75429	0.701	0.512
heart weight	heart weight, weight	-2.6774	3.4769	-0.74000	0.651	0.448
hematology	basophil differential (percent of total WBC)	-0.040690	0.032567	-0.60954	0.662	0.224
hematology	calculated hemoglobin (cHGB)	0.33537	0.15178	0.78216	0.202	0.0369
hematology	eosinophil differential (percent of total WBC)	-0.20433	0.28235	-0.50085	0.813	0.476
hematology	hematocrit (HCT)	0.86381	0.48303	0.62138	0.340	0.0864
hematology	hemoglobin concentration distribution width (HDW)	-0.054065	0.020367	-1.3571	0.139	0.0139
hematology	large unstained cells (percent of total WBC)	0.16754	0.071345	1.0711	0.235	0.0274
hematology	lymphocyte differential (percent of total WBC)	4.1333	1.6088	1.3511	0.123	0.0168
hematology	mean corpuscular hemoglobin (CHr)	-0.14153	0.051353	-1.1282	0.0593	0.0110
hematology	mean platelet volume (MPV)	-0.10665	0.063305	-0.84436	0.272	0.105
hematology	mean RBC corpuscular hemoglobin (MCH)	-0.20922	0.081461	-0.74336	0.171	0.0169
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	0.36293	0.21268	0.75314	0.423	0.101
hematology	mean RBC corpuscular volume (MCV)	-1.2110	0.24418	-1.6486	0.00111	0.0000516
hematology	measured hemoglobin (mHGB)	0.28047	0.14683	0.50085	0.302	0.0681
hematology	monocyte differential (percent of total WBC)	-0.13053	0.10679	-0.23588	0.593	0.233
hematology	neutrophil differential (percent of total WBC)	-3.8737	1.5207	-1.4455	0.126	0.0177
hematology	platelet count (PLT; units per volume x 10³)	-81.327	54.567	-0.98874	0.522	0.149
hematology	RBC corpuscular distribution width (RDW)	-0.21790	0.13952	-0.82764	0.371	0.132
hematology	RBC corpuscular hemoglobin concentration mean (CHCM)	0.50567	0.19017	1.2025	0.0885	0.0140
hematology	red blood cell count (RBC; per volume x 10⁶)	0.33550	0.11467	1.1242	0.0825	0.00740
hematology	reticulocyte count (Retic; units per volume x 10⁹)	10.336	12.025	0.54420	0.753	0.399
hematology	reticulocyte differential (percent of total RBC)	-0.051385	0.13958	0.00074825	0.888	0.716
hematology	white blood cell count (WBC; units per volume x 10³)	1.0490	0.47019	0.88487	0.130	0.0353
holeboard	number of hole pokes by individual hole number, 20 min test, 1	-1.0164	0.90869	-0.97147	0.728	0.269
holeboard	number of hole pokes by individual hole number, 20 min test, 2	-0.27949	0.50739	-0.31842	0.890	0.584
holeboard	number of hole pokes by individual hole number, 20 min test, 3	-0.38309	0.48531	-0.57247	0.853	0.434
holeboard	number of hole pokes by individual hole number, 20 min test, 4	0.095975	0.52902	0.18075	0.958	0.857
holeboard	number of hole pokes by individual hole number, 20 min test, 5	0.76443	0.79049	1.2459	0.790	0.338
holeboard	number of hole pokes by individual hole number, 20 min test, 6	-0.30000	0.26668	-0.82302	0.834	0.266
holeboard	number of hole pokes by individual hole number, 20 min test, 7	0.43750	0.30741	1.1194	0.738	0.161
holeboard	number of hole pokes by individual hole number, 20 min test, 8	-0.36250	0.42980	-0.49270	0.832	0.403
holeboard	number of hole pokes by individual hole number, 20 min test, 9	0.19702	0.38356	0.44312	0.923	0.610
holeboard	number of hole pokes by individual hole number, 20 min test, 10	0.022726	0.22131	0.13743	0.983	0.919
holeboard	number of hole pokes by individual hole number, 20 min test, 11	0.22074	0.30895	0.57589	0.878	0.478
holeboard	number of hole pokes by individual hole number, 20 min test, 12	-0.22731	0.43162	-0.29609	0.903	0.601
holeboard	number of hole pokes by individual hole number, 20 min test, 13	0.047194	0.70211	0.12515	0.992	0.947
holeboard	number of hole pokes by individual hole number, 20 min test, 14	0.42500	0.44012	0.74948	0.744	0.339
holeboard	number of hole pokes by individual hole number, 20 min test, 15	0.012500	0.38669	0.11326	0.988	0.974
holeboard	number of hole pokes by individual hole number, 20 min test, 16	-0.92302	0.80747	-0.78113	0.679	0.258
holeboard	total number of hole pokes, 20 min test	-1.2536	4.0697	-0.075980	0.887	0.759
light / dark	fecal boli count, 20 min test	1.0959	0.70878	1.1763	0.529	0.129
light / dark	latency to enter dark zone, 20 min test	43.844	31.811	0.66856	0.605	0.175
light / dark	number of transitions between light and dark zones, 20 min test	5.2707	7.9658	0.57664	0.768	0.511
light / dark	percentage of total time in dark zone, 20 min test	-1.8259	3.9052	-0.20697	0.877	0.642
light / dark	percentage of total time in light zone, 20 min test	1.8259	3.9052	0.20283	0.876	0.642
light / dark	time mobile in dark zone, 20 min test	16.681	11.105	0.84509	0.424	0.140
light / dark	time mobile in light zone, 20 min test	21.830	11.420	0.95882	0.244	0.0619
light / dark	time spent in dark zone, 20 min test	-52.883	49.216	-0.57345	0.691	0.288
light / dark	time spent in light zone, 20 min test	52.883	49.216	0.57345	0.691	0.288
open field	average speed in center of arena, 20 min test	0.26799	0.51451	0.39466	0.837	0.606
open field	average speed in periphery of arena, 20 min test	0.46022	0.15822	1.1539	0.0442	0.00645
open field	distance traveled habituation ratio, 20 min test	1.8751	7.3681	0.18977	0.923	0.801
open field	distance traveled in center of arena, 20 min test	107.50	98.117	0.36150	0.536	0.281
open field	distance traveled in periphery of arena, 20 min test	521.36	152.75	1.4396	0.0205	0.00172
open field	distance traveled slope, 20 min test	2.2076	6.9168	0.27671	0.909	0.752
open field	distance traveled, 20 min test, 1st 5min	157.56	72.014	0.86754	0.159	0.0359
open field	distance traveled, 20 min test, 2nd 5min	144.05	57.315	1.0764	0.0951	0.0170
open field	distance traveled, 20 min test, 3rd 5min	146.65	61.823	1.0909	0.116	0.0237
open field	distance traveled, 20 min test, 4th 5min	174.43	56.928	1.3117	0.0388	0.00433
open field	number of clockwise revolution episodes, 20 min test	1.5679	1.6887	0.50264	0.712	0.360
open field	number of counter-clockwise revolution episodes, 20 min test	4.0767	1.2627	1.5731	0.0511	0.00281
open field	number of fecal boli, 20 min test	0.058536	0.87168	0.32456	0.983	0.947
open field	number of rears in 5 min bins, 20 min test, 1st 5min	6.2426	2.9439	1.4470	0.196	0.0416
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	5.2994	3.3600	1.0229	0.380	0.124
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	9.0453	3.5389	1.5871	0.118	0.0154
open field	number of rears in 5 min bins, 20 min test, 4th 5min	6.3447	3.9196	1.0551	0.358	0.115
open field	percentage of total time in center of arena, 20 min test	-0.31772	3.1780	-0.27113	0.979	0.921
open field	percentage of total time in center of arena, slope, 20 min test	1.2004	1.5375	0.79914	0.835	0.441
open field	percentage of total time in center, habituation ratio, 20 min test	1.1195	1.5571	0.72902	0.845	0.477
open field	percentage of total time in corners of arena, 20 min test	-2.8473	4.2660	-0.20757	0.771	0.509
open field	percentage of total time in corners, habituation ratio, 20 min test	-0.15457	2.3246	-0.36580	0.994	0.947
open field	percentage of total time in corners, slope, 20 min test	-0.16673	2.3451	-0.33439	0.987	0.944
open field	permanence time in center of arena, 20 min test	-3.7903	38.133	-0.26835	0.978	0.921
open field	permanence time in corners of arena, 20 min test	-34.162	51.190	-0.20757	0.771	0.509
open field	permanence time in periphery of arena, 20 min test	3.7833	38.134	0.26835	0.978	0.922
open field	total distance traveled, 20 min test	620.12	208.91	1.1644	0.0367	0.00554
open field	total number of rears, 20 min test	27.074	12.208	1.4064	0.160	0.0336
open field	whole arena average speed, 20 min test	0.51597	0.17420	1.1644	0.0371	0.00563
open field	whole arena resting time, 20 min test	-58.349	19.913	-0.98945	0.0378	0.00610
open field	whole arena time spent mobile, 20 min test	58.194	19.893	1.1859	0.0403	0.00618
open field	whole arena time spent vertical, 20 min test	25.641	12.398	1.6733	0.254	0.0465
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	-1.7584	1.4330	-0.53849	0.547	0.228
startle / PPI	average baseline movement during background noise	0.17682	0.96635	0.22681	0.985	0.856
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	0.019587	0.060442	0.070816	0.898	0.748
startle / PPI	average of each corrected percent pre-pulse inhibition value	-0.011438	0.056071	-0.18266	0.932	0.839
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.42725	6.2493	0.11444	0.995	0.946
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.95155	6.8893	-0.13845	0.965	0.891
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-3.9762	14.993	-0.51430	0.921	0.792
startle / PPI	average startle response to full pulse (120 dB)	120.41	40.696	1.8312	0.0420	0.00517
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	112.90	35.686	1.7609	0.0273	0.00297
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	95.476	36.940	1.6638	0.0744	0.0135
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	125.18	81.990	1.9479	0.331	0.135
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	-1.4231	1.3306	-0.96556	0.785	0.291
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	-1.4758	1.2953	-0.99731	0.779	0.261
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	4.4125	3.4903	1.4324	0.656	0.213
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.011483	0.066306	0.14978	0.974	0.863
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.031280	0.075775	-0.38449	0.884	0.682
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-0.012987	0.078345	-0.28416	0.946	0.869
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	120.03	40.847	1.8312	0.0431	0.00545
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	113.72	35.752	1.7675	0.0254	0.00284
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	97.003	37.099	1.6866	0.0705	0.0125
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	77.110	36.238	1.6052	0.156	0.0396
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.051194	0.071008	0.47315	0.910	0.475
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.0060083	0.079164	-0.13358	0.975	0.940
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.015164	0.082100	-0.065938	0.949	0.854
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	411.20	148.59	1.7609	0.0574	0.00852
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	385.98	125.34	1.7226	0.0315	0.00374
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	118.06	130.27	0.82931	0.589	0.370
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	104.98	133.16	0.86338	0.635	0.435
startle / PPI	maximum baseline movement during background noise	-0.72839	2.2740	-0.11867	0.954	0.750
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	4.3715	6.7148	0.46845	0.923	0.519
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.85410	7.4477	-0.0049040	0.969	0.909
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.63900	7.3206	-0.098941	0.972	0.931
startle / PPI	maximum startle response to full pulse (120 dB)	410.74	148.35	1.7478	0.0573	0.00849
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	356.62	127.68	1.6312	0.0493	0.00797
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	297.38	136.05	1.4979	0.137	0.0347
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	261.44	129.82	1.5154	0.180	0.0508
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	-2.8758	2.8407	-0.79809	0.772	0.317
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	-5.4703	3.0731	-1.4093	0.570	0.0827
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	12.848	9.3214	1.6259	0.546	0.176

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

In this plot, data points are the computed genotype effect % vs. C57BL/6NJ controls, for all measured categorical phenotypes in JaxKOMP-EAP

Dimensions Width: × Height: px

Plot Options Group by Procedure

Significance Threshold p-Value Threshold

Download Plot

Procedure	JaxKOMP-EAP Trait	Trait Effect	P-value

eye morphology	anterior chamber depth	1.0 %	1.0
eye morphology	bulging eye	1.0 %	1.00
eye morphology	cornea	3.0 %	1.00
eye morphology	cornea opacity	6.0 %	0.249
eye morphology	cornea vascularization	2.0 %	1.00
eye morphology	corneal deposits	1.0 %	1.00
eye morphology	corneal mineralization	1.0 %	1.00
eye morphology	corneal scleralization	2.0 %	1.00
eye morphology	corneal ulcer	1.0 %	1.00
eye morphology	eye closure	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	1.0 %	1.00
eye morphology	eyelid morphology	1.0 %	1.0
eye morphology	eyes (present, absent)	0.0 %	1.0
eye morphology	fusion between cornea and lens	3.0 %	1.00
eye morphology	iris pigmentation	2.0 %	1.00
eye morphology	iris transillumination	1.0 %	1.00
eye morphology	irispupil	3.0 %	1.00
eye morphology	lacrimation	3.0 %	1.0
eye morphology	lens	9.0 %	1.0
eye morphology	lens opacity	12.0 %	0.0148
eye morphology	narrow eye opening	1.0 %	1.0
eye morphology	optic disc	3.0 %	1.00
eye morphology	persistence of hyaloid vascular system	9.0 %	0.261
eye morphology	pupil dilation	2.0 %	1.0
eye morphology	pupil light response	2.0 %	1.00
eye morphology	pupil position	4.0 %	1.00
eye morphology	pupil shape	3.0 %	1.00
eye morphology	retina	9.0 %	0.503
eye morphology	retinal blood vessels	3.0 %	1.0
eye morphology	retinal blood vessels pattern	12.0 %	0.0156
eye morphology	retinal blood vessels structure	3.0 %	1.00
eye morphology	retinal pigmentation	5.0 %	0.496
eye morphology	retinal structure	3.0 %	1.00
eye morphology	synechia	3.0 %	1.00
eye morphology	vitreous	3.0 %	1.00
SHIRPA	activity body position	1.0 %	1.00
SHIRPA	aggression	1.0 %	1.0
SHIRPA	body length	0.0 %	1.00
SHIRPA	body position	0.0 %	1.0
SHIRPA	body thickness	0.0 %	1.0
SHIRPA	coat color abdomen	4.0 %	1.0
SHIRPA	coat color back	0.0 %	1.00
SHIRPA	coat color head	0.0 %	1.0
SHIRPA	coat color pattern abdomen	1.0 %	1.0
SHIRPA	coat color pattern back	0.0 %	1.0
SHIRPA	coat color pattern head	0.0 %	1.00
SHIRPA	coat hair abdomen texture appearance	2.0 %	1.0
SHIRPA	coat hair back texture appearance	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	1.0 %	1.00
SHIRPA	coat hair distribution back	0.0 %	1.0
SHIRPA	coat hair distribution head	1.0 %	1.0
SHIRPA	coat hair head texture appearance	0.0 %	1.0
SHIRPA	contact righting	5.0 %	1.00
SHIRPA	ear morphology	0.0 %	1.0
SHIRPA	fat distribution	0.0 %	1.00
SHIRPA	forelimb digit number	0.0 %	1.00
SHIRPA	forelimb digit position	0.0 %	1.0
SHIRPA	forelimb digit shape	0.0 %	1.0
SHIRPA	forelimb digit size	0.0 %	1.0
SHIRPA	forelimb footpads	0.0 %	1.0
SHIRPA	forelimb nail length	0.0 %	1.0
SHIRPA	forelimb nail number	0.0 %	1.0
SHIRPA	forelimb nail position	0.0 %	1.0
SHIRPA	forelimb nail shape	0.0 %	1.0
SHIRPA	forelimbs position	0.0 %	1.0
SHIRPA	forelimbs shape	0.0 %	1.0
SHIRPA	forelimbs size	0.0 %	1.0
SHIRPA	forepaw position	0.0 %	1.0
SHIRPA	forepaw shape	0.0 %	1.0
SHIRPA	forepaw size	0.0 %	1.0
SHIRPA	gait (fluidity)	0.0 %	1.00
SHIRPA	genitalia morphology	0.0 %	1.00
SHIRPA	genitalia presence	0.0 %	1.0
SHIRPA	genitalia size	0.0 %	1.0
SHIRPA	head bobbing	0.0 %	1.0
SHIRPA	head morphology	0.0 %	1.0
SHIRPA	head size	0.0 %	1.00
SHIRPA	hindlimb digit number	0.0 %	1.00
SHIRPA	hindlimb digit position	0.0 %	1.0
SHIRPA	hindlimb digit shape	0.0 %	1.0
SHIRPA	hindlimb digit size	0.0 %	1.00
SHIRPA	hindlimb nail length	0.0 %	1.00
SHIRPA	hindlimb nail number	0.0 %	1.00
SHIRPA	hindlimb nail position	0.0 %	1.0
SHIRPA	hindlimb nail shape	0.0 %	1.0
SHIRPA	hindlimbs footpads	0.0 %	1.0
SHIRPA	hindlimbs position	0.0 %	1.0
SHIRPA	hindlimbs shape	0.0 %	1.0
SHIRPA	hindlimbs size	0.0 %	1.0
SHIRPA	hindpaw position	0.0 %	1.0
SHIRPA	hindpaw shape	0.0 %	1.0
SHIRPA	hindpaw size	0.0 %	1.0
SHIRPA	limb grasp	7.0 %	0.624
SHIRPA	lower lip morphology	0.0 %	1.0
SHIRPA	lower teeth appearance	0.0 %	1.00
SHIRPA	mouth morphology	0.0 %	1.00
SHIRPA	salivation	0.0 %	1.0
SHIRPA	skin color back paws	0.0 %	1.0
SHIRPA	skin color ear	0.0 %	1.0
SHIRPA	skin color front paws	0.0 %	1.0
SHIRPA	skin color snout	0.0 %	1.0
SHIRPA	skin color tail	0.0 %	1.0
SHIRPA	skin color whole body	0.0 %	1.0
SHIRPA	skin texture back paw	0.0 %	1.0
SHIRPA	skin texture ear	0.0 %	1.0
SHIRPA	skin texture front paws	0.0 %	1.0
SHIRPA	skin texture snout	0.0 %	1.0
SHIRPA	skin texture tail	0.0 %	1.0
SHIRPA	skin texture whole body	0.0 %	1.00
SHIRPA	snout size	0.0 %	1.0
SHIRPA	startle response	0.0 %	1.00
SHIRPA	tail curvature	0.0 %	1.0
SHIRPA	tail elevation	17.0 %	0.00147
SHIRPA	tail length	0.0 %	1.00
SHIRPA	tail morphology	0.0 %	1.00
SHIRPA	tail presence	0.0 %	1.0
SHIRPA	tail shape	0.0 %	1.00
SHIRPA	tail thickness	0.0 %	1.0
SHIRPA	teeth presence	0.0 %	1.00
SHIRPA	transfer arousal	1.0 %	1.0
SHIRPA	tremor	0.0 %	1.00
SHIRPA	trunk curl	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	0.0 %	1.00
SHIRPA	upper lip morphology	0.0 %	1.0
SHIRPA	upper teeth appearance	0.0 %	1.00
SHIRPA	vibrissae appearance	1.0 %	1.0
SHIRPA	vibrissae presence	2.0 %	1.0
SHIRPA	vocalization	2.0 %	1.00

GENOTYPE CORRELATION PLOT

Correlate Gsto1^em1(IMPC)J/Mmjax -/- with genotype:

This genotype correlation visualization can include both EAP and LAP measures.