MPD: JaxKOMP-LAP genotype: Dnajb2<sup>em1(IMPC)J</sup> -/-

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Late Adult Phenotyping study (LAP)

Procedure	JaxKOMP-LAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value
body composition	body length	0.042663	0.074756	0.64067	0.818	0.574
body composition	body weight (at time of DXA)	4.0893	2.1736	0.94467	0.196	0.0732
body composition	bone area, whole body scan, head excluded	-0.10596	0.36405	0.086543	0.899	0.774
body composition	bone mineral content of whole body scan, head excluded	-0.015192	0.019474	-0.10826	0.713	0.444
body composition	bone mineral content to body weight ratio	-0.00047376	0.00046230	-0.21780	0.598	0.317
body composition	bone mineral density of whole body scan, head excluded	-0.0011489	0.00054646	-0.35293	0.209	0.0472
body composition	fat tissue mass of whole body scan, head excluded	-0.46194	0.87893	-0.49487	0.848	0.605
body composition	fat tissue mass to body weight ratio	-0.013988	0.015442	-0.51945	0.692	0.375
body composition	lean tissue mass of whole body scan, head excluded	1.5998	0.74383	1.6284	0.246	0.0427
body composition	lean tissue mass to body weight ratio	0.018885	0.015220	0.67449	0.597	0.228
body composition	percent fat, whole body scan, head excluded	-1.6072	1.5013	-0.62118	0.612	0.297
body composition	ratio of soft-tissue attenuation coefficients	0.0017698	0.0016676	0.58802	0.627	0.301
body composition	tissue area	0.38165	0.43211	0.70187	0.707	0.387
body composition	total tissue mass, whole body scan, head excluded	0.88516	0.88944	0.84780	0.771	0.331
clinical blood chemistry	alanine transaminase (plasma ALT)	-5.7181	13.734	-0.52440	0.891	0.683
clinical blood chemistry	albumin (plasma Alb)	-0.18571	0.62263	-0.12824	0.924	0.770
clinical blood chemistry	alkaline phosphatase (plasma ALP)	-18.910	16.112	-1.2381	0.846	0.259
clinical blood chemistry	aspartate transaminase (plasma AST)	-10.599	12.130	-1.0428	0.735	0.397
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	0.018162	0.17934	0.18722	0.949	0.921
clinical blood chemistry	blood urea nitrogen (BUN)	2.6342	2.1015	0.92218	0.615	0.229
clinical blood chemistry	calcium (plasma Ca)	0.0020086	0.13620	-0.25335	0.988	0.988
clinical blood chemistry	creatinine (plasma)	-0.033563	0.022260	-0.81366	0.492	0.152
clinical blood chemistry	glucose (plasma GLU, no fast)	4.6272	19.727	-0.086973	0.909	0.818
clinical blood chemistry	HDL cholesterol (plasma HDL)	6.2830	5.4867	0.62890	0.633	0.271
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	-0.017329	0.015618	-0.56179	0.527	0.285
clinical blood chemistry	phosphorus (plasma phosphate)	0.20958	0.36110	0.28940	0.707	0.570
clinical blood chemistry	total bilirubin (plasma TBIL)	0.0023224	0.0058151	0.037988	0.928	0.695
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	10.373	7.5995	0.81366	0.565	0.194
clinical blood chemistry	total protein (plasma TP)	-1.4271	0.85467	-0.89171	0.576	0.117
clinical blood chemistry	triglyceride (plasma TG, no fast)	-12.769	11.440	-0.77957	0.706	0.282
EKG	duration of PQ interval	-3.2410	0.93307	-2.0454	0.0871	0.00181
EKG	duration of PR interval	-3.0889	0.99467	-2.0454	0.218	0.00455
EKG	duration of QRS interval	0.39429	0.33178	0.82713	0.965	0.245
EKG	duration of QT interval	0.44891	0.87127	0.39360	0.841	0.611
EKG	duration of QTC interval, calculated by dividing QT interval by square root of preceding RR interval	0.38177	0.82223	0.33889	0.862	0.646
EKG	duration of RR interval	-1.1233	1.4165	-0.75712	0.773	0.435
EKG	duration of ST interval	0.019457	0.94084	0.18001	1.00	0.984
EKG	heart rate coefficient of variation (signal intensity)	-2.7744	1.5160	-1.7413	0.478	0.0783
EKG	heart rate variability, mean of differences between sequential beats; beats per min	-22.596	11.901	-1.7413	0.475	0.0684
EKG	heart rate, beats per min	11.837	12.927	0.98113	0.757	0.368
EKG	mean R amplitude, mean amplitude of signal measured from isoelectric line to peak of QRS	-0.083419	0.072407	-0.75712	0.905	0.259
EKG	mean SR amplitude, mean amplitude of signal measured from signal minimum line to peak of QRS	-0.12043	0.12556	-0.75712	0.814	0.346
EKG	number of signals	-7.6271	7.7935	-0.56595	0.810	0.336
EKG	proportion of number pairs of successive beat-to-beat intervals that exceed 50 ms	-4.7797	4.6078	-1.2671	0.780	0.309
EKG	QT dispersion, measured as inter-lead variability of QT intervals	-9.6666	3.2196	-1.7413	0.281	0.00585
EKG	QTc dispersion, calculated as rate-corrected QT dispersion	-10.946	3.4309	-1.5446	0.177	0.00369
EKG	root mean square of successive differences of neighboring RR intervals	-3.9253	2.4699	-0.98113	0.570	0.124
glucose tolerance test	amount glucose injected	1.5735	6.1301	-0.082277	0.916	0.800
glucose tolerance test	plasma glucose, 0min	13.228	9.6567	0.74047	0.495	0.186
glucose tolerance test	plasma glucose, 15min	55.969	38.564	0.97842	0.472	0.161
glucose tolerance test	plasma glucose, 30min	31.435	30.242	0.63629	0.657	0.310
glucose tolerance test	plasma glucose, 60min	47.463	24.238	1.0470	0.330	0.0636
glucose tolerance test	plasma glucose, 120min	17.118	21.958	0.29173	0.753	0.444
grip strength	body weight (at time of grip strength test)	4.4143	1.6121	1.0364	0.0503	0.0101
grip strength	forelimb and hindlimb grip strength (mean of trials), average	14.812	6.6935	0.90273	0.175	0.0347
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	0.26469	0.15575	0.70095	0.294	0.0996
grip strength	forelimb and hindlimb grip strength by trial, trial1	8.4605	8.6527	0.38532	0.634	0.336
grip strength	forelimb and hindlimb grip strength by trial, trial2	8.2248	10.440	0.52440	0.758	0.437
grip strength	forelimb and hindlimb grip strength by trial, trial3	15.568	10.705	0.84162	0.465	0.156
grip strength	forelimb grip strength (mean of trials), average	7.2981	3.7345	0.93459	0.376	0.0601
grip strength	forelimb grip strength (mean of trials), average normalized to bw	0.12516	0.078216	0.67449	0.491	0.120
grip strength	forelimb grip strength by trial, trial1	2.1122	3.1275	0.14674	0.858	0.504
grip strength	forelimb grip strength by trial, trial2	7.2266	5.3625	0.87177	0.662	0.188
grip strength	forelimb grip strength by trial, trial3	8.9820	4.6061	1.0729	0.512	0.0603
heart weight	heart weight, normalized to body weight	0.099378	0.11301	0.22689	0.672	0.387
heart weight	heart weight, weight	7.5865	5.7453	0.72979	0.549	0.197
hematology	basophil differential (percent of total WBC)	-0.14161	0.077772	-1.2816	0.807	0.0901
hematology	calculated hemoglobin (cHGB)	-0.42573	0.42483	-0.56595	0.626	0.333
hematology	eosinophil differential (percent of total WBC)	-1.0736	1.2147	-1.3517	0.682	0.392
hematology	hematocrit (HCT)	-1.1472	1.2697	-0.84162	0.760	0.382
hematology	hemoglobin concentration distribution width (HDW)	-0.033019	0.051025	-0.46049	0.804	0.527
hematology	large unstained cells (percent of total WBC)	-0.58483	0.26703	-1.6684	0.525	0.0447
hematology	lymphocyte differential (percent of total WBC)	6.1769	4.0419	1.1325	0.586	0.147
hematology	mean corpuscular hemoglobin (CHr)	-0.41218	0.17870	-1.4758	0.289	0.0369
hematology	mean platelet volume (MPV)	-0.17635	0.25007	-0.59110	0.760	0.491
hematology	mean RBC corpuscular hemoglobin (MCH)	-0.19169	0.17991	-0.60018	0.654	0.305
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	0.12114	0.52282	0.36800	0.902	0.820
hematology	mean RBC corpuscular volume (MCV)	-1.0352	0.56116	-1.2323	0.363	0.0849
hematology	measured hemoglobin (mHGB)	-0.23596	0.49672	-0.43073	0.863	0.642
hematology	monocyte differential (percent of total WBC)	-0.52905	0.62068	-0.60724	0.729	0.407
hematology	neutrophil differential (percent of total WBC)	-5.1121	3.2679	-1.1809	0.630	0.139
hematology	platelet count (PLT; units per volume x 10³)	164.01	114.88	0.84872	0.610	0.174
hematology	RBC corpuscular distribution width (RDW)	-0.20776	0.33607	-0.49585	0.844	0.546
hematology	RBC corpuscular hemoglobin concentration mean (CHCM)	-0.36558	0.30901	-0.73632	0.608	0.256
hematology	red blood cell count (RBC; per volume x 10⁶)	0.088046	0.29848	0.062085	0.910	0.772
hematology	reticulocyte count (Retic; units per volume x 10⁹)	-63.788	43.414	-1.4104	0.941	0.164
hematology	reticulocyte differential (percent of total RBC)	-0.78384	0.62566	-1.1445	0.852	0.231
hematology	white blood cell count (WBC; units per volume x 10³)	-0.36465	1.1142	-0.23800	0.928	0.748
holeboard	number of hole pokes by individual hole number, 20 min test, 1	0.64371	0.89948	0.33889	0.849	0.481
holeboard	number of hole pokes by individual hole number, 20 min test, 2	0.20916	0.73868	0.10463	0.962	0.780
holeboard	number of hole pokes by individual hole number, 20 min test, 3	-0.47877	0.57900	-0.85644	0.892	0.417
holeboard	number of hole pokes by individual hole number, 20 min test, 4	1.3043	0.68998	1.1139	0.499	0.0720
holeboard	number of hole pokes by individual hole number, 20 min test, 5	-0.41643	0.80369	-0.65035	0.986	0.610
holeboard	number of hole pokes by individual hole number, 20 min test, 6	-0.067315	0.24777	-0.25335	0.906	0.788
holeboard	number of hole pokes by individual hole number, 20 min test, 7	0.42516	0.34374	0.89729	0.701	0.229
holeboard	number of hole pokes by individual hole number, 20 min test, 8	0.66817	0.47484	1.0676	0.798	0.173
holeboard	number of hole pokes by individual hole number, 20 min test, 9	0.043333	0.74620	0.25863	0.986	0.954
holeboard	number of hole pokes by individual hole number, 20 min test, 10	0.77410	0.68234	1.8627	0.863	0.268
holeboard	number of hole pokes by individual hole number, 20 min test, 11	0.64232	0.41296	1.3238	0.613	0.134
holeboard	number of hole pokes by individual hole number, 20 min test, 12	0.46018	0.48559	0.79164	0.941	0.354
holeboard	number of hole pokes by individual hole number, 20 min test, 13	2.6703	0.68798	2.0454	0.0366	0.000755
holeboard	number of hole pokes by individual hole number, 20 min test, 14	0.78329	0.47484	1.1628	0.649	0.113
holeboard	number of hole pokes by individual hole number, 20 min test, 15	0.63269	0.75942	0.68262	0.724	0.413
holeboard	number of hole pokes by individual hole number, 20 min test, 16	1.2732	0.76661	0.98113	0.709	0.111
holeboard	total number of hole pokes, 20 min test	10.295	4.4373	1.1628	0.323	0.0300
light / dark	fecal boli count, 20 min test	0.44628	1.1077	0.19105	0.884	0.691
light / dark	latency to enter dark zone, 20 min test	31.886	97.169	0.53594	0.905	0.746
light / dark	number of transitions between light and dark zones, 20 min test	-7.9288	9.3242	-0.70630	0.810	0.404
light / dark	percentage of total time in dark zone, 20 min test	3.2734	3.8974	0.29499	0.805	0.410
light / dark	percentage of total time in light zone, 20 min test	-3.2734	3.8974	-0.29499	0.805	0.410
light / dark	time mobile in dark zone, 20 min test	-18.999	22.314	-0.96210	0.774	0.403
light / dark	time mobile in light zone, 20 min test	4.7417	13.101	0.25335	0.896	0.721
light / dark	time spent in dark zone, 20 min test	54.464	91.378	0.11052	0.842	0.557
light / dark	time spent in light zone, 20 min test	-54.464	91.378	-0.11052	0.842	0.557
open field	average speed in center of arena, 20 min test	-0.11017	0.51706	-0.46958	0.913	0.833
open field	average speed in periphery of arena, 20 min test	0.16304	0.20482	0.35487	0.729	0.434
open field	distance traveled habituation ratio, 20 min test	-14.491	7.6587	-1.1453	0.341	0.0711
open field	distance traveled in center of arena, 20 min test	42.304	123.98	0.052685	0.889	0.736
open field	distance traveled in periphery of arena, 20 min test	244.79	183.75	0.61612	0.578	0.196
open field	distance traveled slope, 20 min test	-16.022	7.6061	-1.3259	0.287	0.0463
open field	distance traveled, 20 min test, 1st 5min	84.068	91.319	0.46958	0.759	0.367
open field	distance traveled, 20 min test, 2nd 5min	121.19	80.860	0.80613	0.388	0.148
open field	distance traveled, 20 min test, 3rd 5min	20.753	62.260	-0.20146	0.881	0.742
open field	distance traveled, 20 min test, 4th 5min	37.974	54.618	0.052685	0.782	0.494
open field	number of clockwise revolution episodes, 20 min test	1.3719	1.3782	0.54140	0.858	0.330
open field	number of counter-clockwise revolution episodes, 20 min test	-1.8549	1.1406	-1.4968	0.473	0.118
open field	number of fecal boli, 20 min test	-3.1145	1.5822	-1.1503	0.313	0.0707
open field	number of rears in 5 min bins, 20 min test, 1st 5min	6.0138	2.0637	1.3259	0.118	0.00781
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	3.1250	3.0519	0.26642	0.602	0.317
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	9.8974	3.1273	1.4351	0.106	0.00449
open field	number of rears in 5 min bins, 20 min test, 4th 5min	7.9012	3.7863	1.1453	0.299	0.0482
open field	percentage of total time in center of arena, 20 min test	12.082	8.3536	1.3784	0.449	0.162
open field	percentage of total time in center of arena, slope, 20 min test	-0.17659	2.6498	0.13735	0.947	0.947
open field	percentage of total time in center, habituation ratio, 20 min test	0.42593	2.5265	0.26642	0.946	0.868
open field	percentage of total time in corners of arena, 20 min test	-17.086	7.2366	-2.1247	0.200	0.0271
open field	percentage of total time in corners, habituation ratio, 20 min test	-4.4565	2.8170	-1.5647	0.526	0.128
open field	percentage of total time in corners, slope, 20 min test	-2.8609	2.8446	-1.1868	0.731	0.325
open field	permanence time in center of arena, 20 min test	145.00	100.24	1.3784	0.449	0.162
open field	permanence time in corners of arena, 20 min test	-205.02	86.838	-2.1247	0.200	0.0271
open field	permanence time in periphery of arena, 20 min test	-144.95	100.24	-1.3784	0.449	0.162
open field	total distance traveled, 20 min test	338.58	267.34	0.59085	0.537	0.219
open field	total number of rears, 20 min test	23.741	10.185	0.92890	0.214	0.0289
open field	whole arena average speed, 20 min test	0.28166	0.22292	0.59085	0.540	0.220
open field	whole arena resting time, 20 min test	-25.956	25.792	-0.37739	0.657	0.325
open field	whole arena time spent mobile, 20 min test	25.901	25.761	0.74913	0.643	0.326
open field	whole arena time spent vertical, 20 min test	17.976	13.143	0.96183	0.656	0.185
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	0.50414	1.5235	0.20354	0.888	0.743

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Late Adult Phenotyping study (LAP)

Procedure	JaxKOMP-LAP Trait	Sex	Trait Effect	P-value
eye morphology	anterior chamber depth	females	2.0 %	1.00
eye morphology	anterior chamber depth	males	1.0 %	1.0
eye morphology	anterior chamber depth	both	2.0 %	1.0
eye morphology	bulging eye	females	2.0 %	1.00
eye morphology	bulging eye	males	1.0 %	1.0
eye morphology	bulging eye	both	2.0 %	1.0
eye morphology	cornea	females	5.0 %	1.00
eye morphology	cornea	males	4.0 %	1.0
eye morphology	cornea	both	5.0 %	1.0
eye morphology	cornea opacity	females	9.0 %	0.454
eye morphology	cornea opacity	males	4.0 %	1.0
eye morphology	cornea opacity	both	4.0 %	0.578
eye morphology	cornea vascularization	females	3.0 %	1.00
eye morphology	cornea vascularization	males	1.0 %	1.0
eye morphology	cornea vascularization	both	2.0 %	1.0
eye morphology	corneal deposits	females	2.0 %	1.00
eye morphology	corneal deposits	males	1.0 %	1.0
eye morphology	corneal deposits	both	1.0 %	1.0
eye morphology	corneal mineralization	females	53.0 %	0.000775
eye morphology	corneal mineralization	males	28.0 %	0.0946
eye morphology	corneal mineralization	both	42.0 %	0.000273
eye morphology	corneal scleralization	females	3.0 %	1.00
eye morphology	corneal scleralization	males	1.0 %	1.0
eye morphology	corneal scleralization	both	2.0 %	1.0
eye morphology	corneal ulcer	females	3.0 %	1.00
eye morphology	corneal ulcer	males	1.0 %	1.0
eye morphology	corneal ulcer	both	2.0 %	1.0
eye morphology	eye closure	females	2.0 %	1.00
eye morphology	eye closure	males	1.0 %	1.0
eye morphology	eye closure	both	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	females	2.0 %	1.00
eye morphology	eye hemorrhage or blood presence	males	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	both	2.0 %	1.0
eye morphology	eyelid morphology	females	2.0 %	1.00
eye morphology	eyelid morphology	males	1.0 %	1.0
eye morphology	eyelid morphology	both	1.0 %	1.0
eye morphology	eyes (present, absent)	females	0.0 %	1.0
eye morphology	eyes (present, absent)	males	0.0 %	1.0
eye morphology	eyes (present, absent)	both	0.0 %	1.0
eye morphology	fusion between cornea and lens	females	5.0 %	1.00
eye morphology	fusion between cornea and lens	males	5.0 %	1.0
eye morphology	fusion between cornea and lens	both	5.0 %	1.0
eye morphology	iris pigmentation	females	2.0 %	1.00
eye morphology	iris pigmentation	males	1.0 %	1.0
eye morphology	iris pigmentation	both	2.0 %	1.0
eye morphology	iris transillumination	females	2.0 %	1.00
eye morphology	iris transillumination	males	1.0 %	1.0
eye morphology	iris transillumination	both	2.0 %	1.0
eye morphology	irispupil	females	4.0 %	1.00
eye morphology	irispupil	males	3.0 %	1.0
eye morphology	irispupil	both	4.0 %	1.0
eye morphology	lacrimation	females	4.0 %	1.0
eye morphology	lacrimation	males	5.0 %	1.0
eye morphology	lacrimation	both	4.0 %	1.0
eye morphology	lens	females	41.0 %	0.150
eye morphology	lens	males	44.0 %	0.111
eye morphology	lens	both	43.0 %	0.0122
eye morphology	lens opacity	females	9.0 %	0.453
eye morphology	lens opacity	males	8.0 %	1.0
eye morphology	lens opacity	both	5.0 %	0.605
eye morphology	narrow eye opening	females	2.0 %	1.00
eye morphology	narrow eye opening	males	1.0 %	1.0
eye morphology	narrow eye opening	both	2.0 %	1.0
eye morphology	optic disc	females	6.0 %	1.0
eye morphology	optic disc	males	5.0 %	1.0
eye morphology	optic disc	both	5.0 %	1.0
eye morphology	persistence of hyaloid vascular system	females	10.0 %	1.00
eye morphology	persistence of hyaloid vascular system	males	7.0 %	1.0
eye morphology	persistence of hyaloid vascular system	both	9.0 %	1.0
eye morphology	pupil dilation	females	3.0 %	1.00
eye morphology	pupil dilation	males	2.0 %	1.0
eye morphology	pupil dilation	both	3.0 %	1.0
eye morphology	pupil light response	females	2.0 %	1.00
eye morphology	pupil light response	males	1.0 %	1.0
eye morphology	pupil light response	both	2.0 %	1.0
eye morphology	pupil position	females	5.0 %	1.0
eye morphology	pupil position	males	3.0 %	1.0
eye morphology	pupil position	both	4.0 %	1.0
eye morphology	pupil shape	females	3.0 %	1.00
eye morphology	pupil shape	males	2.0 %	1.0
eye morphology	pupil shape	both	3.0 %	1.0
eye morphology	retina	females	15.0 %	0.0299
eye morphology	retina	males	14.0 %	1.0
eye morphology	retina	both	5.0 %	0.348
eye morphology	retinal blood vessels	females	5.0 %	1.00
eye morphology	retinal blood vessels	males	5.0 %	1.0
eye morphology	retinal blood vessels	both	5.0 %	1.0
eye morphology	retinal blood vessels pattern	females	5.0 %	1.00
eye morphology	retinal blood vessels pattern	males	5.0 %	1.0
eye morphology	retinal blood vessels pattern	both	5.0 %	1.0
eye morphology	retinal blood vessels structure	females	6.0 %	1.0
eye morphology	retinal blood vessels structure	males	5.0 %	1.0
eye morphology	retinal blood vessels structure	both	5.0 %	1.0
eye morphology	retinal pigmentation	females	7.0 %	1.0
eye morphology	retinal pigmentation	males	6.0 %	1.0
eye morphology	retinal pigmentation	both	7.0 %	1.0
eye morphology	retinal structure	females	6.0 %	1.00
eye morphology	retinal structure	males	5.0 %	1.0
eye morphology	retinal structure	both	6.0 %	1.0
eye morphology	synechia	females	5.0 %	1.00
eye morphology	synechia	males	5.0 %	1.0
eye morphology	synechia	both	5.0 %	1.0
eye morphology	vitreous	females	5.0 %	1.00
eye morphology	vitreous	males	5.0 %	1.0
eye morphology	vitreous	both	5.0 %	1.0
SHIRPA	activity body position	females	4.0 %	1.00
SHIRPA	activity body position	males	28.0 %	0.0132
SHIRPA	activity body position	both	12.0 %	0.0651
SHIRPA	aggression	females	1.0 %	1.00
SHIRPA	aggression	males	0.0 %	1.0
SHIRPA	aggression	both	0.0 %	1.0
SHIRPA	body length	females	0.0 %	1.0
SHIRPA	body length	males	0.0 %	1.0
SHIRPA	body length	both	0.0 %	1.0
SHIRPA	body position	females	3.0 %	1.00
SHIRPA	body position	males	29.0 %	0.00884
SHIRPA	body position	both	13.0 %	0.0758
SHIRPA	body thickness	females	4.0 %	1.0
SHIRPA	body thickness	males	4.0 %	1.0
SHIRPA	body thickness	both	4.0 %	1.0
SHIRPA	coat color abdomen	females	11.0 %	0.605
SHIRPA	coat color abdomen	males	29.0 %	0.0662
SHIRPA	coat color abdomen	both	20.0 %	0.0321
SHIRPA	coat color back	females	14.0 %	0.616
SHIRPA	coat color back	males	18.0 %	0.370
SHIRPA	coat color back	both	16.0 %	0.0927
SHIRPA	coat color head	females	0.0 %	1.0
SHIRPA	coat color head	males	7.0 %	1.0
SHIRPA	coat color head	both	4.0 %	1.0
SHIRPA	coat color pattern abdomen	females	2.0 %	1.0
SHIRPA	coat color pattern abdomen	males	7.0 %	1.0
SHIRPA	coat color pattern abdomen	both	4.0 %	1.0
SHIRPA	coat color pattern back	females	44.0 %	0.00000561
SHIRPA	coat color pattern back	males	6.0 %	0.650
SHIRPA	coat color pattern back	both	25.0 %	0.00416
SHIRPA	coat color pattern head	females	1.0 %	1.0
SHIRPA	coat color pattern head	males	7.0 %	1.0
SHIRPA	coat color pattern head	both	4.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	females	0.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	males	0.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	both	0.0 %	1.0
SHIRPA	coat hair back texture appearance	females	1.0 %	1.0
SHIRPA	coat hair back texture appearance	males	1.0 %	1.00
SHIRPA	coat hair back texture appearance	both	1.0 %	1.0
SHIRPA	coat hair distribution abdomen	females	51.0 %	0.0000398
SHIRPA	coat hair distribution abdomen	males	6.0 %	0.360
SHIRPA	coat hair distribution abdomen	both	29.0 %	0.000163
SHIRPA	coat hair distribution back	females	11.0 %	0.605
SHIRPA	coat hair distribution back	males	5.0 %	0.437
SHIRPA	coat hair distribution back	both	3.0 %	1.0
SHIRPA	coat hair distribution head	females	10.0 %	0.737
SHIRPA	coat hair distribution head	males	10.0 %	0.725
SHIRPA	coat hair distribution head	both	10.0 %	0.468
SHIRPA	coat hair head texture appearance	females	1.0 %	1.0
SHIRPA	coat hair head texture appearance	males	2.0 %	1.0
SHIRPA	coat hair head texture appearance	both	2.0 %	1.0
SHIRPA	contact righting	females	8.0 %	1.00
SHIRPA	contact righting	males	53.0 %	0.00351
SHIRPA	contact righting	both	23.0 %	0.108
SHIRPA	ear morphology	females	0.0 %	1.0
SHIRPA	ear morphology	males	0.0 %	1.0
SHIRPA	ear morphology	both	0.0 %	1.0
SHIRPA	eye morphology	females	2.0 %	1.0
SHIRPA	eye morphology	males	1.0 %	1.0
SHIRPA	eye morphology	both	2.0 %	1.00
SHIRPA	fat distribution	females	39.0 %	0.00166
SHIRPA	fat distribution	males	14.0 %	0.466
SHIRPA	fat distribution	both	26.0 %	0.0108
SHIRPA	forelimb digit number	females	0.0 %	1.0
SHIRPA	forelimb digit number	males	0.0 %	1.0
SHIRPA	forelimb digit number	both	0.0 %	1.0
SHIRPA	forelimb digit position	females	0.0 %	1.0
SHIRPA	forelimb digit position	males	0.0 %	1.0
SHIRPA	forelimb digit position	both	0.0 %	1.0
SHIRPA	forelimb digit shape	females	0.0 %	1.0
SHIRPA	forelimb digit shape	males	0.0 %	1.0
SHIRPA	forelimb digit shape	both	0.0 %	1.0
SHIRPA	forelimb digit size	females	0.0 %	1.0
SHIRPA	forelimb digit size	males	0.0 %	1.0
SHIRPA	forelimb digit size	both	0.0 %	1.0
SHIRPA	forelimb footpads	females	0.0 %	1.0
SHIRPA	forelimb footpads	males	0.0 %	1.0
SHIRPA	forelimb footpads	both	0.0 %	1.0
SHIRPA	forelimb nail length	females	0.0 %	1.0
SHIRPA	forelimb nail length	males	0.0 %	1.0
SHIRPA	forelimb nail length	both	0.0 %	1.0
SHIRPA	forelimb nail number	females	0.0 %	1.0
SHIRPA	forelimb nail number	males	0.0 %	1.0
SHIRPA	forelimb nail number	both	0.0 %	1.0
SHIRPA	forelimb nail position	females	0.0 %	1.0
SHIRPA	forelimb nail position	males	0.0 %	1.0
SHIRPA	forelimb nail position	both	0.0 %	1.0
SHIRPA	forelimb nail shape	females	0.0 %	1.0
SHIRPA	forelimb nail shape	males	0.0 %	1.0
SHIRPA	forelimb nail shape	both	0.0 %	1.0
SHIRPA	forelimbs position	females	0.0 %	1.0
SHIRPA	forelimbs position	males	0.0 %	1.0
SHIRPA	forelimbs position	both	0.0 %	1.0
SHIRPA	forelimbs shape	females	0.0 %	1.0
SHIRPA	forelimbs shape	males	0.0 %	1.0
SHIRPA	forelimbs shape	both	0.0 %	1.0
SHIRPA	forelimbs size	females	0.0 %	1.0
SHIRPA	forelimbs size	males	0.0 %	1.0
SHIRPA	forelimbs size	both	0.0 %	1.0
SHIRPA	forepaw position	females	0.0 %	1.0
SHIRPA	forepaw position	males	0.0 %	1.0
SHIRPA	forepaw position	both	0.0 %	1.0
SHIRPA	forepaw shape	females	0.0 %	1.0
SHIRPA	forepaw shape	males	0.0 %	1.0
SHIRPA	forepaw shape	both	0.0 %	1.0
SHIRPA	forepaw size	females	0.0 %	1.0
SHIRPA	forepaw size	males	0.0 %	1.0
SHIRPA	forepaw size	both	0.0 %	1.0
SHIRPA	gait (fluidity)	females	1.0 %	1.0
SHIRPA	gait (fluidity)	males	3.0 %	1.00
SHIRPA	gait (fluidity)	both	2.0 %	1.0
SHIRPA	genitalia morphology	females	0.0 %	1.0
SHIRPA	genitalia morphology	males	0.0 %	1.0
SHIRPA	genitalia morphology	both	0.0 %	1.0
SHIRPA	genitalia presence	females	0.0 %	1.0
SHIRPA	genitalia presence	males	0.0 %	1.0
SHIRPA	genitalia presence	both	0.0 %	1.0
SHIRPA	genitalia size	females	0.0 %	1.0
SHIRPA	genitalia size	males	0.0 %	1.0
SHIRPA	genitalia size	both	0.0 %	1.0
SHIRPA	head bobbing	females	0.0 %	1.0
SHIRPA	head bobbing	males	1.0 %	1.00
SHIRPA	head bobbing	both	0.0 %	1.0
SHIRPA	head morphology	females	1.0 %	1.0
SHIRPA	head morphology	males	0.0 %	1.0
SHIRPA	head morphology	both	0.0 %	1.0
SHIRPA	head size	females	0.0 %	1.0
SHIRPA	head size	males	0.0 %	1.0
SHIRPA	head size	both	0.0 %	1.0
SHIRPA	hindlimb digit number	females	0.0 %	1.0
SHIRPA	hindlimb digit number	males	1.0 %	1.0
SHIRPA	hindlimb digit number	both	0.0 %	1.00
SHIRPA	hindlimb digit position	females	0.0 %	1.0
SHIRPA	hindlimb digit position	males	0.0 %	1.0
SHIRPA	hindlimb digit position	both	0.0 %	1.0
SHIRPA	hindlimb digit shape	females	1.0 %	1.0
SHIRPA	hindlimb digit shape	males	1.0 %	1.00
SHIRPA	hindlimb digit shape	both	1.0 %	1.0
SHIRPA	hindlimb digit size	females	0.0 %	1.0
SHIRPA	hindlimb digit size	males	1.0 %	1.0
SHIRPA	hindlimb digit size	both	0.0 %	1.00
SHIRPA	hindlimb nail length	females	2.0 %	1.00
SHIRPA	hindlimb nail length	males	9.0 %	1.00
SHIRPA	hindlimb nail length	both	6.0 %	1.0
SHIRPA	hindlimb nail number	females	0.0 %	1.0
SHIRPA	hindlimb nail number	males	0.0 %	1.0
SHIRPA	hindlimb nail number	both	0.0 %	1.0
SHIRPA	hindlimb nail position	females	0.0 %	1.0
SHIRPA	hindlimb nail position	males	0.0 %	1.0
SHIRPA	hindlimb nail position	both	0.0 %	1.0
SHIRPA	hindlimb nail shape	females	0.0 %	1.0
SHIRPA	hindlimb nail shape	males	0.0 %	1.0
SHIRPA	hindlimb nail shape	both	0.0 %	1.0
SHIRPA	hindlimbs footpads	females	0.0 %	1.0
SHIRPA	hindlimbs footpads	males	1.0 %	1.00
SHIRPA	hindlimbs footpads	both	1.0 %	1.0
SHIRPA	hindlimbs position	females	0.0 %	1.0
SHIRPA	hindlimbs position	males	2.0 %	1.00
SHIRPA	hindlimbs position	both	1.0 %	1.0
SHIRPA	hindlimbs shape	females	0.0 %	1.0
SHIRPA	hindlimbs shape	males	7.0 %	0.465
SHIRPA	hindlimbs shape	both	4.0 %	0.476
SHIRPA	hindlimbs size	females	0.0 %	1.0
SHIRPA	hindlimbs size	males	1.0 %	1.0
SHIRPA	hindlimbs size	both	1.0 %	1.00
SHIRPA	hindpaw position	females	0.0 %	1.0
SHIRPA	hindpaw position	males	0.0 %	1.0
SHIRPA	hindpaw position	both	0.0 %	1.0
SHIRPA	hindpaw shape	females	0.0 %	1.0
SHIRPA	hindpaw shape	males	1.0 %	1.00
SHIRPA	hindpaw shape	both	0.0 %	1.0
SHIRPA	hindpaw size	females	1.0 %	1.0
SHIRPA	hindpaw size	males	2.0 %	1.0
SHIRPA	hindpaw size	both	1.0 %	1.00
SHIRPA	limb grasp	females	6.0 %	1.0
SHIRPA	limb grasp	males	57.0 %	0.000926
SHIRPA	limb grasp	both	25.0 %	0.0373
SHIRPA	lower lip morphology	females	0.0 %	1.0
SHIRPA	lower lip morphology	males	0.0 %	1.0
SHIRPA	lower lip morphology	both	0.0 %	1.0
SHIRPA	lower teeth appearance	females	0.0 %	1.0
SHIRPA	lower teeth appearance	males	0.0 %	1.0
SHIRPA	lower teeth appearance	both	0.0 %	1.0
SHIRPA	mouth morphology	females	0.0 %	1.0
SHIRPA	mouth morphology	males	0.0 %	1.0
SHIRPA	mouth morphology	both	0.0 %	1.0
SHIRPA	salivation	females	0.0 %	1.0
SHIRPA	salivation	males	0.0 %	1.0
SHIRPA	salivation	both	0.0 %	1.0
SHIRPA	skin color back paws	females	0.0 %	1.0
SHIRPA	skin color back paws	males	0.0 %	1.0
SHIRPA	skin color back paws	both	0.0 %	1.0
SHIRPA	skin color ear	females	0.0 %	1.0
SHIRPA	skin color ear	males	0.0 %	1.0
SHIRPA	skin color ear	both	0.0 %	1.0
SHIRPA	skin color front paws	females	0.0 %	1.0
SHIRPA	skin color front paws	males	0.0 %	1.0
SHIRPA	skin color front paws	both	0.0 %	1.0
SHIRPA	skin color snout	females	0.0 %	1.0
SHIRPA	skin color snout	males	0.0 %	1.0
SHIRPA	skin color snout	both	0.0 %	1.0
SHIRPA	skin color tail	females	1.0 %	1.0
SHIRPA	skin color tail	males	0.0 %	1.0
SHIRPA	skin color tail	both	0.0 %	1.0
SHIRPA	skin color whole body	females	0.0 %	1.0
SHIRPA	skin color whole body	males	0.0 %	1.0
SHIRPA	skin color whole body	both	0.0 %	1.0
SHIRPA	skin texture back paw	females	0.0 %	1.0
SHIRPA	skin texture back paw	males	0.0 %	1.0
SHIRPA	skin texture back paw	both	0.0 %	1.0
SHIRPA	skin texture ear	females	0.0 %	1.0
SHIRPA	skin texture ear	males	0.0 %	1.0
SHIRPA	skin texture ear	both	0.0 %	1.0
SHIRPA	skin texture front paws	females	0.0 %	1.0
SHIRPA	skin texture front paws	males	0.0 %	1.0
SHIRPA	skin texture front paws	both	0.0 %	1.0
SHIRPA	skin texture snout	females	0.0 %	1.0
SHIRPA	skin texture snout	males	0.0 %	1.0
SHIRPA	skin texture snout	both	0.0 %	1.0
SHIRPA	skin texture tail	females	0.0 %	1.0
SHIRPA	skin texture tail	males	0.0 %	1.0
SHIRPA	skin texture tail	both	0.0 %	1.0
SHIRPA	skin texture whole body	females	0.0 %	1.0
SHIRPA	skin texture whole body	males	0.0 %	1.0
SHIRPA	skin texture whole body	both	0.0 %	1.0
SHIRPA	snout size	females	1.0 %	1.0
SHIRPA	snout size	males	1.0 %	1.00
SHIRPA	snout size	both	1.0 %	1.0
SHIRPA	startle response	females	27.0 %	0.119
SHIRPA	startle response	males	53.0 %	0.00164
SHIRPA	startle response	both	13.0 %	0.275
SHIRPA	tail curvature	females	0.0 %	1.0
SHIRPA	tail curvature	males	1.0 %	1.00
SHIRPA	tail curvature	both	1.0 %	1.00
SHIRPA	tail elevation	females	2.0 %	1.0
SHIRPA	tail elevation	males	3.0 %	1.0
SHIRPA	tail elevation	both	2.0 %	1.0
SHIRPA	tail length	females	0.0 %	1.0
SHIRPA	tail length	males	0.0 %	1.0
SHIRPA	tail length	both	0.0 %	1.0
SHIRPA	tail morphology	females	7.0 %	0.349
SHIRPA	tail morphology	males	0.0 %	1.0
SHIRPA	tail morphology	both	3.0 %	0.359
SHIRPA	tail presence	females	0.0 %	1.0
SHIRPA	tail presence	males	0.0 %	1.0
SHIRPA	tail presence	both	0.0 %	1.0
SHIRPA	tail shape	females	1.0 %	1.00
SHIRPA	tail shape	males	0.0 %	1.0
SHIRPA	tail shape	both	0.0 %	1.0
SHIRPA	tail thickness	females	1.0 %	1.0
SHIRPA	tail thickness	males	0.0 %	1.0
SHIRPA	tail thickness	both	1.0 %	1.0
SHIRPA	teeth presence	females	0.0 %	1.0
SHIRPA	teeth presence	males	0.0 %	1.0
SHIRPA	teeth presence	both	0.0 %	1.0
SHIRPA	transfer arousal	females	6.0 %	1.00
SHIRPA	transfer arousal	males	25.0 %	0.0421
SHIRPA	transfer arousal	both	10.0 %	0.188
SHIRPA	tremor	females	1.0 %	1.00
SHIRPA	tremor	males	2.0 %	1.0
SHIRPA	tremor	both	2.0 %	1.0
SHIRPA	trunk curl	females	0.0 %	1.0
SHIRPA	trunk curl	males	0.0 %	1.0
SHIRPA	trunk curl	both	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	females	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	males	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	both	0.0 %	1.0
SHIRPA	upper lip morphology	females	0.0 %	1.0
SHIRPA	upper lip morphology	males	0.0 %	1.0
SHIRPA	upper lip morphology	both	0.0 %	1.0
SHIRPA	upper teeth appearance	females	0.0 %	1.0
SHIRPA	upper teeth appearance	males	0.0 %	1.0
SHIRPA	upper teeth appearance	both	0.0 %	1.0
SHIRPA	vibrissae appearance	females	5.0 %	1.00
SHIRPA	vibrissae appearance	males	3.0 %	1.00
SHIRPA	vibrissae appearance	both	4.0 %	1.00
SHIRPA	vibrissae presence	females	35.0 %	0.0317
SHIRPA	vibrissae presence	males	12.0 %	0.724
SHIRPA	vibrissae presence	both	23.0 %	0.0439
SHIRPA	vocalization	females	92.0 %	4.92e-9
SHIRPA	vocalization	males	94.0 %	0.00000135
SHIRPA	vocalization	both	93.0 %	4.15e-15

GENOTYPE CORRELATION PLOT

Correlate Dnajb2^em1(IMPC)J -/- with genotype:

This genotype correlation visualization can include both EAP and LAP measures.