MPD: JaxKOMP-EAP genotype: Rprd1a<sup>em1(IMPC)J</sup> -/-

JaxKOMP-EAP effect sizes: Rprd1a^em1(IMPC)J -/- Gene Rprd1a

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	4.3957	2.4078	0.99540	0.472	0.0929
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	3.0000	1.9536	0.66961	0.638	0.151
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	2.3963	1.3476	0.32294	0.450	0.103
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	1.2824	1.8942	0.082428	0.804	0.512
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	0.50000	3.2634	0.044876	0.963	0.881
body composition	body length	-0.0049986	0.043768	0.12186	0.974	0.910
body composition	body weight (at time of DXA)	0.18891	0.55518	0.25871	0.864	0.735
body composition	bone area, whole body scan, head excluded	-0.038151	0.14917	0.020480	0.913	0.799
body composition	bone mineral content of whole body scan, head excluded	-0.0042935	0.010253	-0.11768	0.856	0.678
body composition	bone mineral content to body weight ratio	-0.00052290	0.00042237	-0.49301	0.486	0.223
body composition	bone mineral density of whole body scan, head excluded	-0.00032692	0.00047865	-0.32457	0.750	0.499
body composition	fat tissue mass of whole body scan, head excluded	0.19355	0.26807	0.33087	0.706	0.475
body composition	fat tissue mass to body weight ratio	0.0043081	0.010160	0.25814	0.836	0.674
body composition	lean tissue mass of whole body scan, head excluded	0.27669	0.27969	0.43823	0.626	0.329
body composition	lean tissue mass to body weight ratio	-0.0074431	0.0090774	-0.46192	0.657	0.417
body composition	percent fat, whole body scan, head excluded	0.44570	0.96599	0.29503	0.818	0.647
body composition	ratio of soft-tissue attenuation coefficients	-0.00048808	0.0010736	-0.29426	0.820	0.652
body composition	tissue area	0.35447	0.17090	1.2316	0.228	0.0447
body composition	total tissue mass, whole body scan, head excluded	0.47851	0.21996	0.79057	0.162	0.0357
clinical blood chemistry	alanine transaminase (plasma ALT)	-4.2667	3.8878	-0.41472	0.649	0.282
clinical blood chemistry	albumin (plasma Alb)	0.11667	0.48107	0.22284	0.936	0.810
clinical blood chemistry	alkaline phosphatase (plasma ALP)	-0.093058	3.7170	-0.54024	0.990	0.980
clinical blood chemistry	aspartate transaminase (plasma AST)	-8.1409	8.1597	-0.39573	0.646	0.328
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	-0.049417	0.28765	-0.14672	0.963	0.865
clinical blood chemistry	blood urea nitrogen (BUN)	1.8532	1.3219	0.73184	0.418	0.173
clinical blood chemistry	calcium (plasma Ca)	0.0029626	0.057263	0.37165	0.976	0.959
clinical blood chemistry	creatinine (plasma)	0.031072	0.020142	0.83697	0.352	0.135
clinical blood chemistry	glucose (plasma GLU, no fast)	-2.5667	7.1571	0.21079	0.843	0.723
clinical blood chemistry	HDL cholesterol (plasma HDL)	1.4710	2.7056	0.031887	0.821	0.591
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	-0.0010500	0.0096836	-0.22610	0.981	0.914
clinical blood chemistry	phosphorus (plasma phosphate)	-0.37000	0.41593	-0.65097	0.661	0.382
clinical blood chemistry	total bilirubin (plasma TBIL)	-0.0028841	0.0067030	-0.22036	0.873	0.670
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	1.9711	3.6164	0.12473	0.832	0.590
clinical blood chemistry	total protein (plasma TP)	0.58880	0.65332	0.37244	0.638	0.375
clinical blood chemistry	triglyceride (plasma TG, no fast)	4.5447	7.2942	0.46872	0.772	0.539
EKG	duration of PQ interval	2.0106	0.81266	2.0355	0.708	0.132
EKG	duration of PR interval	1.6117	1.4009	1.6952	0.877	0.369
EKG	duration of QRS interval	-0.35625	0.35675	-1.0991	0.905	0.423
EKG	duration of QT interval	0.024929	2.0739	0.18850	0.999	0.992
EKG	duration of QTC interval, calculated by dividing QT interval by square root of preceding RR interval	0.19276	1.6365	0.27547	0.999	0.917
EKG	duration of RR interval	0.47389	2.5327	0.48821	0.946	0.869
EKG	duration of ST interval	0.66838	1.4392	0.88491	0.936	0.688
EKG	heart rate coefficient of variation (signal intensity)	-0.93256	1.8696	-0.67956	0.940	0.667
EKG	heart rate variability, mean of differences between sequential beats; beats per min	-6.7171	13.256	-0.72599	0.932	0.663
EKG	heart rate, beats per min	-4.0482	19.499	-0.49889	0.956	0.855
EKG	mean R amplitude, mean amplitude of signal measured from isoelectric line to peak of QRS	0.020597	0.077067	0.055485	0.940	0.814
EKG	mean SR amplitude, mean amplitude of signal measured from signal minimum line to peak of QRS	-0.031250	0.10411	-0.25793	0.925	0.792
EKG	number of signals	10.113	5.5071	1.5798	0.721	0.208
EKG	proportion of number pairs of successive beat-to-beat intervals that exceed 50 ms	-7.0269	3.7681	-1.2733	0.814	0.203
EKG	QT dispersion, measured as inter-lead variability of QT intervals	2.1979	7.3444	0.69230	0.977	0.793
EKG	QTc dispersion, calculated as rate-corrected QT dispersion	1.0260	7.4818	0.28385	0.986	0.903
EKG	root mean square of successive differences of neighboring RR intervals	-0.21794	3.3220	-0.0020150	0.989	0.954
glucose tolerance test	amount glucose injected	-5.2792	6.2264	-1.0983	0.802	0.486
glucose tolerance test	plasma glucose, 0min	14.304	23.490	1.1671	0.784	0.605
glucose tolerance test	plasma glucose, 15min	73.123	20.834	1.9037	0.316	0.0725
glucose tolerance test	plasma glucose, 30min	17.579	45.509	0.64632	0.897	0.737
glucose tolerance test	plasma glucose, 60min	-30.676	22.866	-1.1671	0.639	0.312
glucose tolerance test	plasma glucose, 120min	-17.347	15.946	-1.2929	0.671	0.390
grip strength	body weight (at time of grip strength test)	1.1489	0.46493	1.2268	0.0757	0.0196
grip strength	forelimb and hindlimb grip strength (mean of trials), average	-6.0086	7.6594	-0.20622	0.639	0.439
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	-0.23088	0.35244	-0.12961	0.702	0.518
grip strength	forelimb and hindlimb grip strength by trial, trial1	-3.3548	9.1658	-0.013071	0.883	0.717
grip strength	forelimb and hindlimb grip strength by trial, trial2	-6.6175	11.558	-0.17664	0.787	0.572
grip strength	forelimb and hindlimb grip strength by trial, trial3	1.5181	11.034	0.31139	0.954	0.892
grip strength	forelimb grip strength (mean of trials), average	9.5813	6.1200	1.4580	0.356	0.128
grip strength	forelimb grip strength (mean of trials), average normalized to bw	0.26236	0.30716	0.91687	0.667	0.400
grip strength	forelimb grip strength by trial, trial1	15.243	7.4599	1.8622	0.285	0.0502
grip strength	forelimb grip strength by trial, trial2	15.297	7.2718	1.7715	0.256	0.0442
grip strength	forelimb grip strength by trial, trial3	-4.2690	7.3404	-0.21662	0.803	0.566
heart weight	heart weight, normalized to body weight	-0.029506	0.10258	-0.56754	0.878	0.775
heart weight	heart weight, weight	-1.9977	2.6195	-0.62895	0.653	0.451
hematology	basophil differential (percent of total WBC)	-0.024125	0.033507	-0.34438	0.815	0.478
hematology	calculated hemoglobin (cHGB)	0.030482	0.17031	-0.18708	0.947	0.859
hematology	eosinophil differential (percent of total WBC)	-0.041667	0.18168	-0.034878	0.946	0.820
hematology	hematocrit (HCT)	-0.025708	0.50868	-0.39698	0.979	0.960
hematology	hemoglobin concentration distribution width (HDW)	-0.0029836	0.023643	-0.069588	0.951	0.901
hematology	large unstained cells (percent of total WBC)	-0.16279	0.12098	-1.0318	0.541	0.190
hematology	lymphocyte differential (percent of total WBC)	2.8117	2.0004	0.95585	0.425	0.171
hematology	mean corpuscular hemoglobin (CHr)	0.053255	0.048547	0.44188	0.516	0.282
hematology	mean platelet volume (MPV)	0.28707	0.092279	1.2775	0.0309	0.00449
hematology	mean RBC corpuscular hemoglobin (MCH)	0.18250	0.078178	0.68712	0.217	0.0273
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	0.34985	0.25054	0.73507	0.533	0.174
hematology	mean RBC corpuscular volume (MCV)	-0.041835	0.23270	-0.072501	0.940	0.859
hematology	measured hemoglobin (mHGB)	0.16449	0.18392	0.17108	0.663	0.379
hematology	monocyte differential (percent of total WBC)	-0.11464	0.14431	-0.17723	0.738	0.434
hematology	neutrophil differential (percent of total WBC)	-2.5667	1.9879	-1.0297	0.460	0.208
hematology	platelet count (PLT; units per volume x 10³)	-4.1833	43.110	-0.0041003	0.971	0.923
hematology	RBC corpuscular distribution width (RDW)	-0.15599	0.11969	-0.56848	0.467	0.203
hematology	RBC corpuscular hemoglobin concentration mean (CHCM)	0.097466	0.17487	0.23899	0.790	0.582
hematology	red blood cell count (RBC; per volume x 10⁶)	-0.012000	0.12191	-0.40336	0.963	0.922
hematology	reticulocyte count (Retic; units per volume x 10⁹)	-18.487	12.484	-0.71870	0.534	0.150
hematology	reticulocyte differential (percent of total RBC)	-0.17940	0.11262	-0.57047	0.464	0.123
hematology	white blood cell count (WBC; units per volume x 10³)	-0.17600	0.62194	0.058804	0.879	0.779
holeboard	number of hole pokes by individual hole number, 20 min test, 1	-0.34821	0.62833	-0.29013	0.866	0.583
holeboard	number of hole pokes by individual hole number, 20 min test, 2	0.0029423	0.40620	0.13801	0.996	0.994
holeboard	number of hole pokes by individual hole number, 20 min test, 3	0.65169	0.45698	1.0503	0.684	0.162
holeboard	number of hole pokes by individual hole number, 20 min test, 4	-0.26901	0.58357	-0.16191	0.896	0.647
holeboard	number of hole pokes by individual hole number, 20 min test, 5	-0.13393	0.45244	-0.11419	0.953	0.769
holeboard	number of hole pokes by individual hole number, 20 min test, 6	-0.11023	0.30510	-0.29609	0.957	0.720
holeboard	number of hole pokes by individual hole number, 20 min test, 7	-0.28716	0.30554	-0.78653	0.860	0.353
holeboard	number of hole pokes by individual hole number, 20 min test, 8	-0.64286	0.49082	-0.94740	0.735	0.198
holeboard	number of hole pokes by individual hole number, 20 min test, 9	-0.41964	0.37991	-0.65134	0.757	0.276
holeboard	number of hole pokes by individual hole number, 20 min test, 10	-0.0089286	0.34984	0.054151	0.997	0.980
holeboard	number of hole pokes by individual hole number, 20 min test, 11	-0.54777	0.45859	-1.4083	0.805	0.240
holeboard	number of hole pokes by individual hole number, 20 min test, 12	-0.62432	0.37403	-0.96116	0.543	0.104
holeboard	number of hole pokes by individual hole number, 20 min test, 13	0.13393	0.62234	0.21935	0.958	0.831
holeboard	number of hole pokes by individual hole number, 20 min test, 14	0.095499	0.54331	0.24708	0.975	0.861
holeboard	number of hole pokes by individual hole number, 20 min test, 15	0.062500	0.36028	0.17463	0.962	0.863
holeboard	number of hole pokes by individual hole number, 20 min test, 16	1.2857	0.79433	1.1334	0.548	0.114
holeboard	total number of hole pokes, 20 min test	-0.91964	4.1927	-0.042183	0.927	0.828
light / dark	fecal boli count, 20 min test	-0.36121	0.56529	-0.36921	0.839	0.526
light / dark	latency to enter dark zone, 20 min test	47.672	24.327	0.72721	0.444	0.0570
light / dark	number of transitions between light and dark zones, 20 min test	-5.0840	7.1725	-0.40858	0.747	0.483
light / dark	percentage of total time in dark zone, 20 min test	5.2321	4.2891	1.0964	0.602	0.230
light / dark	percentage of total time in light zone, 20 min test	-5.2321	4.2891	-1.1013	0.602	0.230
light / dark	time mobile in dark zone, 20 min test	1.3304	11.906	0.0054081	0.969	0.912
light / dark	time mobile in light zone, 20 min test	-10.254	11.516	-0.95882	0.640	0.379
light / dark	time spent in dark zone, 20 min test	23.828	47.035	0.55442	0.879	0.615
light / dark	time spent in light zone, 20 min test	-23.828	47.035	-0.55442	0.879	0.615
open field	average speed in center of arena, 20 min test	0.39503	0.39781	0.60488	0.662	0.327
open field	average speed in periphery of arena, 20 min test	0.10458	0.11882	-0.088054	0.606	0.384
open field	distance traveled habituation ratio, 20 min test	14.225	6.7543	1.1618	0.254	0.0417
open field	distance traveled in center of arena, 20 min test	5.5473	78.641	-0.35148	0.972	0.944
open field	distance traveled in periphery of arena, 20 min test	155.90	135.36	0.18703	0.497	0.256
open field	distance traveled slope, 20 min test	13.055	6.1929	1.1181	0.253	0.0415
open field	distance traveled, 20 min test, 1st 5min	-53.670	72.269	-0.77172	0.694	0.462
open field	distance traveled, 20 min test, 2nd 5min	68.222	37.195	0.26418	0.244	0.0743
open field	distance traveled, 20 min test, 3rd 5min	74.849	38.460	0.38308	0.214	0.0589
open field	distance traveled, 20 min test, 4th 5min	74.824	42.833	0.35577	0.269	0.0885
open field	number of clockwise revolution episodes, 20 min test	-0.048903	0.94864	-0.43368	0.985	0.959
open field	number of counter-clockwise revolution episodes, 20 min test	1.6459	1.0184	0.46686	0.375	0.114
open field	number of fecal boli, 20 min test	1.6525	0.81838	1.4450	0.275	0.0504
open field	number of rears in 5 min bins, 20 min test, 1st 5min	-7.2143	2.1453	-2.0686	0.0321	0.00174
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	-5.8200	2.1149	-1.6843	0.0838	0.00894
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	-5.4196	2.5783	-1.5284	0.201	0.0421
open field	number of rears in 5 min bins, 20 min test, 4th 5min	-5.8661	3.0600	-1.6733	0.267	0.0626
open field	percentage of total time in center of arena, 20 min test	-2.9992	3.0243	-0.93194	0.644	0.327
open field	percentage of total time in center of arena, slope, 20 min test	-0.25018	1.9990	-0.016783	0.968	0.901
open field	percentage of total time in center, habituation ratio, 20 min test	-0.098661	2.1777	0.070545	0.986	0.964
open field	percentage of total time in corners of arena, 20 min test	2.5846	3.6493	0.76992	0.750	0.483
open field	percentage of total time in corners, habituation ratio, 20 min test	0.91054	2.1162	0.13534	0.937	0.669
open field	percentage of total time in corners, slope, 20 min test	1.6473	1.9044	0.48038	0.832	0.392
open field	permanence time in center of arena, 20 min test	-35.991	36.289	-0.93194	0.645	0.327
open field	permanence time in corners of arena, 20 min test	31.036	43.790	0.77172	0.750	0.483
open field	permanence time in periphery of arena, 20 min test	36.039	36.295	0.92987	0.645	0.327
open field	total distance traveled, 20 min test	162.65	157.05	0.0087270	0.528	0.307
open field	total number of rears, 20 min test	-24.348	8.3911	-1.9662	0.0550	0.00607
open field	whole arena average speed, 20 min test	0.13513	0.13082	0.0073843	0.530	0.308
open field	whole arena resting time, 20 min test	-20.854	15.123	-0.054402	0.357	0.176
open field	whole arena time spent mobile, 20 min test	20.971	15.114	0.30613	0.358	0.173
open field	whole arena time spent vertical, 20 min test	-29.849	8.6220	-2.0688	0.0248	0.00132
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	2.5000	2.1164	1.2300	0.567	0.251

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Sex	Trait Effect	P-value
eye morphology	anterior chamber depth	females	1.0 %	1.0
eye morphology	anterior chamber depth	males	0.0 %	1.0
eye morphology	anterior chamber depth	both	1.0 %	1.0
eye morphology	bulging eye	females	1.0 %	1.0
eye morphology	bulging eye	males	0.0 %	1.0
eye morphology	bulging eye	both	1.0 %	1.00
eye morphology	cornea	females	4.0 %	1.0
eye morphology	cornea	males	2.0 %	1.0
eye morphology	cornea	both	3.0 %	1.00
eye morphology	cornea opacity	females	5.0 %	1.00
eye morphology	cornea opacity	males	24.0 %	0.00403
eye morphology	cornea opacity	both	11.0 %	0.123
eye morphology	cornea vascularization	females	3.0 %	1.0
eye morphology	cornea vascularization	males	1.0 %	1.0
eye morphology	cornea vascularization	both	2.0 %	1.00
eye morphology	corneal deposits	females	2.0 %	1.0
eye morphology	corneal deposits	males	1.0 %	1.0
eye morphology	corneal deposits	both	1.0 %	1.00
eye morphology	corneal mineralization	females	2.0 %	1.0
eye morphology	corneal mineralization	males	1.0 %	1.0
eye morphology	corneal mineralization	both	1.0 %	1.00
eye morphology	corneal scleralization	females	3.0 %	1.00
eye morphology	corneal scleralization	males	1.0 %	1.0
eye morphology	corneal scleralization	both	2.0 %	1.00
eye morphology	corneal ulcer	females	1.0 %	1.0
eye morphology	corneal ulcer	males	1.0 %	1.0
eye morphology	corneal ulcer	both	1.0 %	1.00
eye morphology	eye closure	females	1.0 %	1.00
eye morphology	eye closure	males	0.0 %	1.0
eye morphology	eye closure	both	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	females	2.0 %	1.00
eye morphology	eye hemorrhage or blood presence	males	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	both	1.0 %	1.00
eye morphology	eyelid morphology	females	1.0 %	1.0
eye morphology	eyelid morphology	males	0.0 %	1.0
eye morphology	eyelid morphology	both	1.0 %	1.0
eye morphology	eyes (present, absent)	females	1.0 %	1.0
eye morphology	eyes (present, absent)	males	0.0 %	1.0
eye morphology	eyes (present, absent)	both	0.0 %	1.0
eye morphology	fusion between cornea and lens	females	4.0 %	1.00
eye morphology	fusion between cornea and lens	males	2.0 %	1.0
eye morphology	fusion between cornea and lens	both	3.0 %	1.00
eye morphology	iris pigmentation	females	2.0 %	1.0
eye morphology	iris pigmentation	males	1.0 %	1.0
eye morphology	iris pigmentation	both	2.0 %	1.00
eye morphology	iris transillumination	females	2.0 %	1.00
eye morphology	iris transillumination	males	1.0 %	1.0
eye morphology	iris transillumination	both	1.0 %	1.00
eye morphology	irispupil	females	4.0 %	1.00
eye morphology	irispupil	males	3.0 %	1.0
eye morphology	irispupil	both	3.0 %	1.00
eye morphology	lacrimation	females	3.0 %	1.0
eye morphology	lacrimation	males	12.0 %	0.0846
eye morphology	lacrimation	both	6.0 %	0.180
eye morphology	lens	females	22.0 %	0.131
eye morphology	lens	males	17.0 %	0.177
eye morphology	lens	both	16.0 %	0.0741
eye morphology	lens opacity	females	12.0 %	0.197
eye morphology	lens opacity	males	24.0 %	0.0186
eye morphology	lens opacity	both	11.0 %	0.0190
eye morphology	narrow eye opening	females	2.0 %	1.0
eye morphology	narrow eye opening	males	1.0 %	1.0
eye morphology	narrow eye opening	both	1.0 %	1.0
eye morphology	optic disc	females	4.0 %	1.00
eye morphology	optic disc	males	12.0 %	0.0619
eye morphology	optic disc	both	6.0 %	0.138
eye morphology	persistence of hyaloid vascular system	females	6.0 %	0.690
eye morphology	persistence of hyaloid vascular system	males	5.0 %	1.0
eye morphology	persistence of hyaloid vascular system	both	3.0 %	0.790
eye morphology	pupil dilation	females	2.0 %	1.0
eye morphology	pupil dilation	males	1.0 %	1.0
eye morphology	pupil dilation	both	2.0 %	1.0
eye morphology	pupil light response	females	2.0 %	1.00
eye morphology	pupil light response	males	1.0 %	1.0
eye morphology	pupil light response	both	2.0 %	1.00
eye morphology	pupil position	females	4.0 %	1.00
eye morphology	pupil position	males	3.0 %	1.0
eye morphology	pupil position	both	4.0 %	1.00
eye morphology	pupil shape	females	3.0 %	1.00
eye morphology	pupil shape	males	2.0 %	1.0
eye morphology	pupil shape	both	3.0 %	1.00
eye morphology	retina	females	10.0 %	0.457
eye morphology	retina	males	16.0 %	1.0
eye morphology	retina	both	7.0 %	0.801
eye morphology	retinal blood vessels	females	4.0 %	1.0
eye morphology	retinal blood vessels	males	2.0 %	1.0
eye morphology	retinal blood vessels	both	3.0 %	1.0
eye morphology	retinal blood vessels pattern	females	5.0 %	1.0
eye morphology	retinal blood vessels pattern	males	2.0 %	1.0
eye morphology	retinal blood vessels pattern	both	4.0 %	1.00
eye morphology	retinal blood vessels structure	females	4.0 %	1.00
eye morphology	retinal blood vessels structure	males	2.0 %	1.0
eye morphology	retinal blood vessels structure	both	3.0 %	1.00
eye morphology	retinal pigmentation	females	25.0 %	0.0424
eye morphology	retinal pigmentation	males	11.0 %	0.188
eye morphology	retinal pigmentation	both	18.0 %	0.0416
eye morphology	retinal structure	females	4.0 %	1.00
eye morphology	retinal structure	males	2.0 %	1.0
eye morphology	retinal structure	both	3.0 %	1.00
eye morphology	synechia	females	4.0 %	1.0
eye morphology	synechia	males	2.0 %	1.0
eye morphology	synechia	both	3.0 %	1.00
eye morphology	vitreous	females	4.0 %	1.00
eye morphology	vitreous	males	2.0 %	1.0
eye morphology	vitreous	both	3.0 %	1.00
SHIRPA	activity body position	females	1.0 %	1.0
SHIRPA	activity body position	males	2.0 %	1.0
SHIRPA	activity body position	both	1.0 %	1.00
SHIRPA	aggression	females	0.0 %	1.00
SHIRPA	aggression	males	1.0 %	1.0
SHIRPA	aggression	both	1.0 %	1.0
SHIRPA	body length	females	0.0 %	1.0
SHIRPA	body length	males	0.0 %	1.00
SHIRPA	body length	both	0.0 %	1.00
SHIRPA	body position	females	0.0 %	1.0
SHIRPA	body position	males	1.0 %	1.0
SHIRPA	body position	both	0.0 %	1.0
SHIRPA	body thickness	females	1.0 %	1.0
SHIRPA	body thickness	males	0.0 %	1.0
SHIRPA	body thickness	both	0.0 %	1.0
SHIRPA	coat color abdomen	females	3.0 %	1.00
SHIRPA	coat color abdomen	males	4.0 %	1.0
SHIRPA	coat color abdomen	both	4.0 %	1.0
SHIRPA	coat color back	females	0.0 %	1.0
SHIRPA	coat color back	males	0.0 %	1.00
SHIRPA	coat color back	both	0.0 %	1.00
SHIRPA	coat color head	females	0.0 %	1.0
SHIRPA	coat color head	males	0.0 %	1.00
SHIRPA	coat color head	both	0.0 %	1.0
SHIRPA	coat color pattern abdomen	females	1.0 %	1.0
SHIRPA	coat color pattern abdomen	males	1.0 %	1.0
SHIRPA	coat color pattern abdomen	both	1.0 %	1.0
SHIRPA	coat color pattern back	females	0.0 %	1.0
SHIRPA	coat color pattern back	males	0.0 %	1.00
SHIRPA	coat color pattern back	both	0.0 %	1.0
SHIRPA	coat color pattern head	females	0.0 %	1.0
SHIRPA	coat color pattern head	males	0.0 %	1.0
SHIRPA	coat color pattern head	both	0.0 %	1.00
SHIRPA	coat hair abdomen texture appearance	females	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	males	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	both	2.0 %	1.0
SHIRPA	coat hair back texture appearance	females	0.0 %	1.0
SHIRPA	coat hair back texture appearance	males	0.0 %	1.0
SHIRPA	coat hair back texture appearance	both	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	females	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	males	1.0 %	1.00
SHIRPA	coat hair distribution abdomen	both	1.0 %	1.00
SHIRPA	coat hair distribution back	females	0.0 %	1.0
SHIRPA	coat hair distribution back	males	0.0 %	1.0
SHIRPA	coat hair distribution back	both	0.0 %	1.0
SHIRPA	coat hair distribution head	females	1.0 %	1.00
SHIRPA	coat hair distribution head	males	1.0 %	1.0
SHIRPA	coat hair distribution head	both	1.0 %	1.0
SHIRPA	coat hair head texture appearance	females	0.0 %	1.00
SHIRPA	coat hair head texture appearance	males	0.0 %	1.0
SHIRPA	coat hair head texture appearance	both	0.0 %	1.0
SHIRPA	contact righting	females	5.0 %	1.0
SHIRPA	contact righting	males	5.0 %	1.00
SHIRPA	contact righting	both	5.0 %	1.00
SHIRPA	ear morphology	females	0.0 %	1.0
SHIRPA	ear morphology	males	0.0 %	1.0
SHIRPA	ear morphology	both	0.0 %	1.0
SHIRPA	fat distribution	females	0.0 %	1.0
SHIRPA	fat distribution	males	0.0 %	1.0
SHIRPA	fat distribution	both	0.0 %	1.00
SHIRPA	forelimb digit number	females	0.0 %	1.00
SHIRPA	forelimb digit number	males	0.0 %	1.0
SHIRPA	forelimb digit number	both	0.0 %	1.00
SHIRPA	forelimb digit position	females	0.0 %	1.0
SHIRPA	forelimb digit position	males	0.0 %	1.0
SHIRPA	forelimb digit position	both	0.0 %	1.0
SHIRPA	forelimb digit shape	females	0.0 %	1.0
SHIRPA	forelimb digit shape	males	0.0 %	1.0
SHIRPA	forelimb digit shape	both	0.0 %	1.0
SHIRPA	forelimb digit size	females	0.0 %	1.0
SHIRPA	forelimb digit size	males	0.0 %	1.0
SHIRPA	forelimb digit size	both	0.0 %	1.0
SHIRPA	forelimb footpads	females	0.0 %	1.0
SHIRPA	forelimb footpads	males	0.0 %	1.0
SHIRPA	forelimb footpads	both	0.0 %	1.0
SHIRPA	forelimb nail length	females	0.0 %	1.0
SHIRPA	forelimb nail length	males	0.0 %	1.0
SHIRPA	forelimb nail length	both	0.0 %	1.0
SHIRPA	forelimb nail number	females	0.0 %	1.0
SHIRPA	forelimb nail number	males	0.0 %	1.0
SHIRPA	forelimb nail number	both	0.0 %	1.0
SHIRPA	forelimb nail position	females	0.0 %	1.0
SHIRPA	forelimb nail position	males	0.0 %	1.0
SHIRPA	forelimb nail position	both	0.0 %	1.0
SHIRPA	forelimb nail shape	females	0.0 %	1.0
SHIRPA	forelimb nail shape	males	0.0 %	1.0
SHIRPA	forelimb nail shape	both	0.0 %	1.0
SHIRPA	forelimbs position	females	0.0 %	1.0
SHIRPA	forelimbs position	males	0.0 %	1.0
SHIRPA	forelimbs position	both	0.0 %	1.0
SHIRPA	forelimbs shape	females	0.0 %	1.0
SHIRPA	forelimbs shape	males	0.0 %	1.0
SHIRPA	forelimbs shape	both	0.0 %	1.0
SHIRPA	forelimbs size	females	0.0 %	1.0
SHIRPA	forelimbs size	males	0.0 %	1.0
SHIRPA	forelimbs size	both	0.0 %	1.0
SHIRPA	forepaw position	females	0.0 %	1.0
SHIRPA	forepaw position	males	0.0 %	1.0
SHIRPA	forepaw position	both	0.0 %	1.0
SHIRPA	forepaw shape	females	0.0 %	1.0
SHIRPA	forepaw shape	males	0.0 %	1.0
SHIRPA	forepaw shape	both	0.0 %	1.0
SHIRPA	forepaw size	females	0.0 %	1.0
SHIRPA	forepaw size	males	0.0 %	1.0
SHIRPA	forepaw size	both	0.0 %	1.0
SHIRPA	gait (fluidity)	females	0.0 %	1.0
SHIRPA	gait (fluidity)	males	0.0 %	1.00
SHIRPA	gait (fluidity)	both	0.0 %	1.00
SHIRPA	genitalia morphology	females	0.0 %	1.00
SHIRPA	genitalia morphology	males	0.0 %	1.0
SHIRPA	genitalia morphology	both	0.0 %	1.00
SHIRPA	genitalia presence	females	0.0 %	1.0
SHIRPA	genitalia presence	males	0.0 %	1.0
SHIRPA	genitalia presence	both	0.0 %	1.0
SHIRPA	genitalia size	females	0.0 %	1.0
SHIRPA	genitalia size	males	0.0 %	1.0
SHIRPA	genitalia size	both	0.0 %	1.0
SHIRPA	head bobbing	females	0.0 %	1.0
SHIRPA	head bobbing	males	0.0 %	1.0
SHIRPA	head bobbing	both	0.0 %	1.0
SHIRPA	head morphology	females	0.0 %	1.0
SHIRPA	head morphology	males	0.0 %	1.00
SHIRPA	head morphology	both	0.0 %	1.0
SHIRPA	head size	females	0.0 %	1.0
SHIRPA	head size	males	0.0 %	1.0
SHIRPA	head size	both	0.0 %	1.00
SHIRPA	hindlimb digit number	females	12.0 %	0.0433
SHIRPA	hindlimb digit number	males	0.0 %	1.0
SHIRPA	hindlimb digit number	both	6.0 %	0.0603
SHIRPA	hindlimb digit position	females	0.0 %	1.0
SHIRPA	hindlimb digit position	males	0.0 %	1.0
SHIRPA	hindlimb digit position	both	0.0 %	1.0
SHIRPA	hindlimb digit shape	females	0.0 %	1.0
SHIRPA	hindlimb digit shape	males	0.0 %	1.0
SHIRPA	hindlimb digit shape	both	0.0 %	1.0
SHIRPA	hindlimb digit size	females	0.0 %	1.00
SHIRPA	hindlimb digit size	males	0.0 %	1.0
SHIRPA	hindlimb digit size	both	0.0 %	1.00
SHIRPA	hindlimb nail length	females	0.0 %	1.0
SHIRPA	hindlimb nail length	males	0.0 %	1.0
SHIRPA	hindlimb nail length	both	0.0 %	1.00
SHIRPA	hindlimb nail number	females	0.0 %	1.0
SHIRPA	hindlimb nail number	males	1.0 %	1.0
SHIRPA	hindlimb nail number	both	0.0 %	1.00
SHIRPA	hindlimb nail position	females	0.0 %	1.0
SHIRPA	hindlimb nail position	males	0.0 %	1.0
SHIRPA	hindlimb nail position	both	0.0 %	1.0
SHIRPA	hindlimb nail shape	females	0.0 %	1.0
SHIRPA	hindlimb nail shape	males	0.0 %	1.0
SHIRPA	hindlimb nail shape	both	0.0 %	1.0
SHIRPA	hindlimbs footpads	females	0.0 %	1.0
SHIRPA	hindlimbs footpads	males	0.0 %	1.0
SHIRPA	hindlimbs footpads	both	0.0 %	1.0
SHIRPA	hindlimbs position	females	0.0 %	1.0
SHIRPA	hindlimbs position	males	0.0 %	1.0
SHIRPA	hindlimbs position	both	0.0 %	1.0
SHIRPA	hindlimbs shape	females	0.0 %	1.0
SHIRPA	hindlimbs shape	males	0.0 %	1.0
SHIRPA	hindlimbs shape	both	0.0 %	1.0
SHIRPA	hindlimbs size	females	0.0 %	1.0
SHIRPA	hindlimbs size	males	0.0 %	1.0
SHIRPA	hindlimbs size	both	0.0 %	1.0
SHIRPA	hindpaw position	females	0.0 %	1.0
SHIRPA	hindpaw position	males	0.0 %	1.0
SHIRPA	hindpaw position	both	0.0 %	1.0
SHIRPA	hindpaw shape	females	0.0 %	1.0
SHIRPA	hindpaw shape	males	0.0 %	1.0
SHIRPA	hindpaw shape	both	0.0 %	1.0
SHIRPA	hindpaw size	females	0.0 %	1.0
SHIRPA	hindpaw size	males	0.0 %	1.0
SHIRPA	hindpaw size	both	0.0 %	1.0
SHIRPA	limb grasp	females	9.0 %	1.00
SHIRPA	limb grasp	males	6.0 %	1.0
SHIRPA	limb grasp	both	7.0 %	0.624
SHIRPA	lower lip morphology	females	0.0 %	1.0
SHIRPA	lower lip morphology	males	0.0 %	1.0
SHIRPA	lower lip morphology	both	0.0 %	1.0
SHIRPA	lower teeth appearance	females	0.0 %	1.0
SHIRPA	lower teeth appearance	males	0.0 %	1.00
SHIRPA	lower teeth appearance	both	0.0 %	1.00
SHIRPA	mouth morphology	females	0.0 %	1.0
SHIRPA	mouth morphology	males	0.0 %	1.00
SHIRPA	mouth morphology	both	0.0 %	1.00
SHIRPA	salivation	females	0.0 %	1.0
SHIRPA	salivation	males	0.0 %	1.0
SHIRPA	salivation	both	0.0 %	1.0
SHIRPA	skin color back paws	females	0.0 %	1.0
SHIRPA	skin color back paws	males	0.0 %	1.0
SHIRPA	skin color back paws	both	0.0 %	1.0
SHIRPA	skin color ear	females	0.0 %	1.0
SHIRPA	skin color ear	males	0.0 %	1.0
SHIRPA	skin color ear	both	0.0 %	1.0
SHIRPA	skin color front paws	females	0.0 %	1.0
SHIRPA	skin color front paws	males	0.0 %	1.0
SHIRPA	skin color front paws	both	0.0 %	1.0
SHIRPA	skin color snout	females	0.0 %	1.0
SHIRPA	skin color snout	males	0.0 %	1.0
SHIRPA	skin color snout	both	0.0 %	1.0
SHIRPA	skin color tail	females	0.0 %	1.0
SHIRPA	skin color tail	males	0.0 %	1.0
SHIRPA	skin color tail	both	0.0 %	1.0
SHIRPA	skin color whole body	females	0.0 %	1.0
SHIRPA	skin color whole body	males	0.0 %	1.0
SHIRPA	skin color whole body	both	0.0 %	1.0
SHIRPA	skin texture back paw	females	0.0 %	1.0
SHIRPA	skin texture back paw	males	0.0 %	1.0
SHIRPA	skin texture back paw	both	0.0 %	1.0
SHIRPA	skin texture ear	females	0.0 %	1.0
SHIRPA	skin texture ear	males	0.0 %	1.0
SHIRPA	skin texture ear	both	0.0 %	1.0
SHIRPA	skin texture front paws	females	0.0 %	1.0
SHIRPA	skin texture front paws	males	0.0 %	1.0
SHIRPA	skin texture front paws	both	0.0 %	1.0
SHIRPA	skin texture snout	females	0.0 %	1.0
SHIRPA	skin texture snout	males	0.0 %	1.0
SHIRPA	skin texture snout	both	0.0 %	1.0
SHIRPA	skin texture tail	females	0.0 %	1.0
SHIRPA	skin texture tail	males	0.0 %	1.0
SHIRPA	skin texture tail	both	0.0 %	1.0
SHIRPA	skin texture whole body	females	0.0 %	1.0
SHIRPA	skin texture whole body	males	0.0 %	1.00
SHIRPA	skin texture whole body	both	0.0 %	1.00
SHIRPA	snout size	females	0.0 %	1.0
SHIRPA	snout size	males	1.0 %	1.0
SHIRPA	snout size	both	0.0 %	1.0
SHIRPA	startle response	females	0.0 %	1.00
SHIRPA	startle response	males	0.0 %	1.00
SHIRPA	startle response	both	0.0 %	1.00
SHIRPA	tail curvature	females	0.0 %	1.00
SHIRPA	tail curvature	males	0.0 %	1.0
SHIRPA	tail curvature	both	0.0 %	1.0
SHIRPA	tail elevation	females	1.0 %	1.00
SHIRPA	tail elevation	males	2.0 %	1.0
SHIRPA	tail elevation	both	1.0 %	1.0
SHIRPA	tail length	females	0.0 %	1.0
SHIRPA	tail length	males	0.0 %	1.0
SHIRPA	tail length	both	0.0 %	1.00
SHIRPA	tail morphology	females	0.0 %	1.00
SHIRPA	tail morphology	males	0.0 %	1.0
SHIRPA	tail morphology	both	0.0 %	1.00
SHIRPA	tail presence	females	0.0 %	1.0
SHIRPA	tail presence	males	0.0 %	1.0
SHIRPA	tail presence	both	0.0 %	1.0
SHIRPA	tail shape	females	0.0 %	1.0
SHIRPA	tail shape	males	0.0 %	1.0
SHIRPA	tail shape	both	0.0 %	1.00
SHIRPA	tail thickness	females	0.0 %	1.0
SHIRPA	tail thickness	males	0.0 %	1.0
SHIRPA	tail thickness	both	0.0 %	1.0
SHIRPA	teeth presence	females	0.0 %	1.0
SHIRPA	teeth presence	males	0.0 %	1.00
SHIRPA	teeth presence	both	0.0 %	1.00
SHIRPA	transfer arousal	females	1.0 %	1.0
SHIRPA	transfer arousal	males	2.0 %	1.00
SHIRPA	transfer arousal	both	1.0 %	1.0
SHIRPA	tremor	females	0.0 %	1.0
SHIRPA	tremor	males	0.0 %	1.0
SHIRPA	tremor	both	0.0 %	1.00
SHIRPA	trunk curl	females	0.0 %	1.00
SHIRPA	trunk curl	males	0.0 %	1.0
SHIRPA	trunk curl	both	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	females	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	males	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	both	0.0 %	1.00
SHIRPA	upper lip morphology	females	0.0 %	1.0
SHIRPA	upper lip morphology	males	0.0 %	1.0
SHIRPA	upper lip morphology	both	0.0 %	1.0
SHIRPA	upper teeth appearance	females	0.0 %	1.0
SHIRPA	upper teeth appearance	males	0.0 %	1.0
SHIRPA	upper teeth appearance	both	0.0 %	1.00
SHIRPA	vibrissae appearance	females	2.0 %	1.0
SHIRPA	vibrissae appearance	males	1.0 %	1.0
SHIRPA	vibrissae appearance	both	1.0 %	1.0
SHIRPA	vibrissae presence	females	2.0 %	1.00
SHIRPA	vibrissae presence	males	1.0 %	1.0
SHIRPA	vibrissae presence	both	2.0 %	1.0
SHIRPA	vocalization	females	2.0 %	1.00
SHIRPA	vocalization	males	2.0 %	1.0
SHIRPA	vocalization	both	2.0 %	1.00

GENOTYPE CORRELATION PLOT

Correlate Rprd1a^em1(IMPC)J -/- with genotype: