MPD: JaxKOMP-EAP genotype: Osbpl10<sup>em1(IMPC)J</sup> -/-

JaxKOMP-EAP effect sizes: Osbpl10^em1(IMPC)J -/- Gene Osbpl10

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

In this plot, data points are the computed genotype effect size vs. C57BL/6NJ controls, for all measured numeric phenotypes in JaxKOMP-EAP

Dimensions Width: × Height: px

Plot Options Group by Procedure Standard Error Show Effect Sizes RankZ

Significance Threshold p-Value Threshold Adjusted Unadjusted

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Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value

ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	3.5212	1.4820	0.76021	0.481	0.0980
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	6.7625	2.5364	1.2877	0.489	0.0759
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	3.2255	1.5377	0.48169	0.479	0.127
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	5.5549	5.6646	0.75865	0.742	0.399
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	5.0735	3.5439	0.78617	0.637	0.248
body composition	body length	-0.0046254	0.039158	0.13016	0.973	0.907
body composition	body weight (at time of DXA)	0.94335	0.51706	0.85021	0.221	0.0754
body composition	bone area, whole body scan, head excluded	-0.20429	0.16156	-0.66084	0.480	0.213
body composition	bone mineral content of whole body scan, head excluded	-0.0083720	0.010956	-0.33809	0.706	0.449
body composition	bone mineral content to body weight ratio	-0.00072035	0.00044425	-0.73577	0.333	0.113
body composition	bone mineral density of whole body scan, head excluded	0.00018224	0.00065563	0.23084	0.899	0.782
body composition	fat tissue mass of whole body scan, head excluded	0.076232	0.30671	0.12731	0.906	0.805
body composition	fat tissue mass to body weight ratio	0.0021673	0.010305	0.18537	0.924	0.834
body composition	lean tissue mass of whole body scan, head excluded	0.60876	0.23323	1.0165	0.124	0.0127
body composition	lean tissue mass to body weight ratio	0.0091637	0.0084636	0.43924	0.541	0.285
body composition	percent fat, whole body scan, head excluded	-0.11828	0.97794	0.0054611	0.961	0.904
body composition	ratio of soft-tissue attenuation coefficients	0.00013516	0.0010720	0.0027365	0.960	0.900
body composition	tissue area	0.45650	0.19934	1.4855	0.170	0.0274
body composition	total tissue mass, whole body scan, head excluded	0.75716	0.24922	1.2351	0.0398	0.00418
clinical blood chemistry	alanine transaminase (plasma ALT)	11.763	9.1224	0.83920	0.592	0.213
clinical blood chemistry	albumin (plasma Alb)	0.45071	0.51798	0.67539	0.699	0.395
clinical blood chemistry	alkaline phosphatase (plasma ALP)	8.4660	3.9120	0.89281	0.179	0.0434
clinical blood chemistry	aspartate transaminase (plasma AST)	12.373	7.9267	0.52831	0.443	0.134
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	-0.024276	0.11802	-0.035492	0.951	0.839
clinical blood chemistry	blood urea nitrogen (BUN)	0.74059	1.4583	0.25276	0.806	0.617
clinical blood chemistry	calcium (plasma Ca)	0.060390	0.064359	0.76619	0.602	0.360
clinical blood chemistry	creatinine (plasma)	0.088232	0.029195	2.0461	0.0589	0.00701
clinical blood chemistry	glucose (plasma GLU, no fast)	-24.984	12.929	-0.62640	0.195	0.0684
clinical blood chemistry	HDL cholesterol (plasma HDL)	6.2256	2.7799	1.0974	0.205	0.0366
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	-0.010430	0.011310	-0.71848	0.683	0.367
clinical blood chemistry	phosphorus (plasma phosphate)	0.10760	0.26186	0.13364	0.856	0.685
clinical blood chemistry	total bilirubin (plasma TBIL)	0.0025092	0.0085641	0.17692	0.919	0.773
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	8.3848	3.4755	1.1162	0.161	0.0256
clinical blood chemistry	total protein (plasma TP)	1.8964	0.61444	1.3201	0.0759	0.00608
clinical blood chemistry	triglyceride (plasma TG, no fast)	19.156	10.653	1.1587	0.317	0.0881
EKG	duration of PQ interval	1.4465	0.70170	1.6543	0.507	0.0483
EKG	duration of PR interval	1.1213	0.65667	1.2388	0.625	0.0984
EKG	duration of QRS interval	0.026054	0.28776	-0.080686	0.990	0.928
EKG	duration of QT interval	-1.5484	0.82623	-1.2089	0.573	0.0710
EKG	duration of QTC interval, calculated by dividing QT interval by square root of preceding RR interval	-2.0936	0.90441	-1.9089	0.563	0.0279
EKG	duration of RR interval	2.1458	0.93664	1.3020	0.350	0.0297
EKG	duration of ST interval	-1.6398	0.80671	-1.3812	0.510	0.0517
EKG	heart rate coefficient of variation (signal intensity)	0.65164	0.79410	0.62227	0.871	0.419
EKG	heart rate variability, mean of differences between sequential beats; beats per min	4.2370	5.5143	0.57170	0.887	0.449
EKG	heart rate, beats per min	-17.526	8.0127	-1.3352	0.323	0.0372
EKG	mean R amplitude, mean amplitude of signal measured from isoelectric line to peak of QRS	-0.13482	0.096732	-1.1919	0.547	0.174
EKG	mean SR amplitude, mean amplitude of signal measured from signal minimum line to peak of QRS	-0.014209	0.11028	-0.14877	0.961	0.898
EKG	number of signals	-17.184	4.7565	-2.2817	0.134	0.00117
EKG	proportion of number pairs of successive beat-to-beat intervals that exceed 50 ms	3.1455	4.6387	0.67961	0.866	0.503
EKG	QT dispersion, measured as inter-lead variability of QT intervals	-0.52456	2.5196	-0.11511	0.982	0.837
EKG	QTc dispersion, calculated as rate-corrected QT dispersion	-0.81100	2.4742	-0.20494	0.966	0.745
EKG	root mean square of successive differences of neighboring RR intervals	1.2903	0.78108	0.79875	0.843	0.109
glucose tolerance test	amount glucose injected	7.9144	5.9057	1.9560	0.578	0.195
glucose tolerance test	plasma glucose, 0min	-1.8100	8.9320	-0.40774	0.921	0.841
glucose tolerance test	plasma glucose, 15min	-8.5027	26.387	-0.13771	0.910	0.751
glucose tolerance test	plasma glucose, 30min	6.4872	21.945	0.32551	0.909	0.771
glucose tolerance test	plasma glucose, 60min	-9.9838	20.518	-0.31107	0.860	0.632
glucose tolerance test	plasma glucose, 120min	-2.2357	9.5405	-0.29239	0.933	0.817
grip strength	body weight (at time of grip strength test)	0.51603	0.36733	0.69281	0.343	0.168
grip strength	forelimb and hindlimb grip strength (mean of trials), average	-10.209	4.8220	-0.47146	0.138	0.0405
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	-0.53889	0.25069	-0.61110	0.143	0.0378
grip strength	forelimb and hindlimb grip strength by trial, trial1	-11.572	6.6975	-0.56279	0.314	0.0917
grip strength	forelimb and hindlimb grip strength by trial, trial2	-15.653	5.6729	-0.74072	0.0724	0.00870
grip strength	forelimb and hindlimb grip strength by trial, trial3	-3.8665	7.9850	-0.050852	0.825	0.631
grip strength	forelimb grip strength (mean of trials), average	-7.3385	4.4630	-0.66631	0.327	0.108
grip strength	forelimb grip strength (mean of trials), average normalized to bw	-0.41412	0.22303	-0.81745	0.259	0.0709
grip strength	forelimb grip strength by trial, trial1	-10.199	5.4735	-0.88419	0.323	0.0698
grip strength	forelimb grip strength by trial, trial2	-8.6725	5.7706	-0.71048	0.442	0.141
grip strength	forelimb grip strength by trial, trial3	-3.4165	5.1759	-0.12376	0.774	0.513
heart weight	heart weight, normalized to body weight	-0.042590	0.10917	-0.62566	0.834	0.700
heart weight	heart weight, weight	-2.2726	3.0849	-0.67746	0.668	0.468
hematology	basophil differential (percent of total WBC)	-0.13452	0.042925	-1.5482	0.166	0.00502
hematology	calculated hemoglobin (cHGB)	-0.16751	0.15735	-0.77276	0.577	0.299
hematology	eosinophil differential (percent of total WBC)	0.19769	0.27595	0.63258	0.815	0.482
hematology	hematocrit (HCT)	0.24324	0.48174	-0.11506	0.802	0.619
hematology	hemoglobin concentration distribution width (HDW)	-0.032256	0.020901	-0.89328	0.415	0.138
hematology	large unstained cells (percent of total WBC)	0.12897	0.11584	0.83816	0.619	0.278
hematology	lymphocyte differential (percent of total WBC)	4.8184	2.5321	1.5596	0.268	0.0709
hematology	mean corpuscular hemoglobin (CHr)	0.037461	0.045012	0.33742	0.656	0.418
hematology	mean platelet volume (MPV)	0.64955	0.12533	1.9210	0.000847	0.0000390
hematology	mean RBC corpuscular hemoglobin (MCH)	0.075637	0.41547	0.26343	0.949	0.857
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	0.055975	1.0708	0.15402	0.987	0.959
hematology	mean RBC corpuscular volume (MCV)	0.48698	0.33154	0.84905	0.350	0.157
hematology	measured hemoglobin (mHGB)	-0.032003	0.48675	-0.31630	0.983	0.948
hematology	monocyte differential (percent of total WBC)	-0.64762	0.50019	-1.3113	0.565	0.209
hematology	neutrophil differential (percent of total WBC)	-4.2217	2.5211	-1.5550	0.319	0.109
hematology	platelet count (PLT; units per volume x 10³)	78.488	53.977	1.0700	0.543	0.161
hematology	RBC corpuscular distribution width (RDW)	-0.14731	0.16573	-0.54130	0.633	0.385
hematology	RBC corpuscular hemoglobin concentration mean (CHCM)	-0.42076	0.26218	-1.1470	0.336	0.123
hematology	red blood cell count (RBC; per volume x 10⁶)	-0.085595	0.098232	-0.69351	0.652	0.393
hematology	reticulocyte count (Retic; units per volume x 10⁹)	-24.364	14.530	-0.95254	0.472	0.112
hematology	reticulocyte differential (percent of total RBC)	-0.20314	0.15184	-0.67590	0.564	0.199
hematology	white blood cell count (WBC; units per volume x 10³)	-0.14164	0.63593	0.084840	0.906	0.826
holeboard	number of hole pokes by individual hole number, 20 min test, 1	-0.16959	0.88807	-0.10230	0.953	0.850
holeboard	number of hole pokes by individual hole number, 20 min test, 2	-0.27542	0.71840	-0.30955	0.935	0.704
holeboard	number of hole pokes by individual hole number, 20 min test, 3	-0.15179	0.34438	-0.16875	0.928	0.662
holeboard	number of hole pokes by individual hole number, 20 min test, 4	-0.12436	0.61293	-0.034610	0.954	0.840
holeboard	number of hole pokes by individual hole number, 20 min test, 5	-0.33389	0.53172	-0.44746	0.880	0.534
holeboard	number of hole pokes by individual hole number, 20 min test, 6	0.10014	0.34202	0.31731	0.968	0.771
holeboard	number of hole pokes by individual hole number, 20 min test, 7	-0.11848	0.32606	-0.36185	0.971	0.719
holeboard	number of hole pokes by individual hole number, 20 min test, 8	-0.14772	0.45481	-0.14312	0.960	0.747
holeboard	number of hole pokes by individual hole number, 20 min test, 9	0.23199	0.36985	0.49593	0.895	0.535
holeboard	number of hole pokes by individual hole number, 20 min test, 10	-0.24576	0.22883	-0.59483	0.834	0.290
holeboard	number of hole pokes by individual hole number, 20 min test, 11	-1.0339	0.50048	-2.4050	0.623	0.0463
holeboard	number of hole pokes by individual hole number, 20 min test, 12	-0.39301	0.40984	-0.58700	0.774	0.344
holeboard	number of hole pokes by individual hole number, 20 min test, 13	0.37182	0.67333	0.45180	0.862	0.584
holeboard	number of hole pokes by individual hole number, 20 min test, 14	0.092161	0.51395	0.24013	0.973	0.859
holeboard	number of hole pokes by individual hole number, 20 min test, 15	-0.058263	0.42894	0.0067474	0.972	0.893
holeboard	number of hole pokes by individual hole number, 20 min test, 16	0.59530	0.80112	0.54934	0.806	0.463
holeboard	total number of hole pokes, 20 min test	-1.9772	4.9096	-0.16949	0.850	0.690
light / dark	fecal boli count, 20 min test	1.6685	0.67585	1.6433	0.293	0.0180
light / dark	latency to enter dark zone, 20 min test	97.443	37.825	1.4911	0.233	0.0138
light / dark	number of transitions between light and dark zones, 20 min test	-9.2699	8.0449	-0.83739	0.584	0.256
light / dark	percentage of total time in dark zone, 20 min test	-3.0255	5.3088	-0.41299	0.833	0.572
light / dark	percentage of total time in light zone, 20 min test	3.0255	5.3088	0.40858	0.831	0.572
light / dark	time mobile in dark zone, 20 min test	-10.871	14.454	-0.78295	0.730	0.456
light / dark	time mobile in light zone, 20 min test	3.5543	9.4848	-0.014873	0.860	0.710
light / dark	time spent in dark zone, 20 min test	-101.15	59.244	-1.1982	0.470	0.0955
light / dark	time spent in light zone, 20 min test	101.15	59.244	1.1982	0.470	0.0955
open field	average speed in center of arena, 20 min test	0.53901	0.44343	0.84047	0.583	0.231
open field	average speed in periphery of arena, 20 min test	0.21733	0.15475	0.32164	0.370	0.168
open field	distance traveled habituation ratio, 20 min test	10.987	7.5133	0.90331	0.465	0.152
open field	distance traveled in center of arena, 20 min test	97.177	86.436	0.28929	0.523	0.268
open field	distance traveled in periphery of arena, 20 min test	268.97	156.85	0.61620	0.278	0.0945
open field	distance traveled slope, 20 min test	10.806	7.1696	0.94866	0.443	0.140
open field	distance traveled, 20 min test, 1st 5min	18.387	72.218	-0.18430	0.916	0.800
open field	distance traveled, 20 min test, 2nd 5min	96.517	58.165	0.56978	0.296	0.105
open field	distance traveled, 20 min test, 3rd 5min	129.48	49.958	0.91958	0.0819	0.0135
open field	distance traveled, 20 min test, 4th 5min	103.31	57.022	0.64074	0.253	0.0779
open field	number of clockwise revolution episodes, 20 min test	-0.22857	1.5295	-0.54891	0.961	0.882
open field	number of counter-clockwise revolution episodes, 20 min test	2.0755	0.93512	0.65565	0.196	0.0325
open field	number of fecal boli, 20 min test	0.65671	0.80141	0.73611	0.710	0.418
open field	number of rears in 5 min bins, 20 min test, 1st 5min	-3.1071	1.8689	-1.0501	0.328	0.104
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	0.10714	2.8441	-0.32872	0.989	0.970
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	1.8125	3.6126	0.12586	0.804	0.619
open field	number of rears in 5 min bins, 20 min test, 4th 5min	0.080357	3.8482	-0.34435	0.995	0.983
open field	percentage of total time in center of arena, 20 min test	-3.0828	3.9386	-0.97208	0.734	0.439
open field	percentage of total time in center of arena, slope, 20 min test	1.3484	1.9351	0.87539	0.856	0.490
open field	percentage of total time in center, habituation ratio, 20 min test	1.6420	2.0624	0.99384	0.839	0.431
open field	percentage of total time in corners of arena, 20 min test	0.81000	4.4573	0.46088	0.947	0.857
open field	percentage of total time in corners, habituation ratio, 20 min test	-2.8459	1.9391	-1.5871	0.636	0.150
open field	percentage of total time in corners, slope, 20 min test	-2.1842	1.8461	-1.3149	0.735	0.244
open field	permanence time in center of arena, 20 min test	-36.991	47.265	-0.97208	0.734	0.439
open field	permanence time in corners of arena, 20 min test	9.7152	53.488	0.46088	0.947	0.857
open field	permanence time in periphery of arena, 20 min test	37.001	47.274	0.96993	0.734	0.439
open field	total distance traveled, 20 min test	347.67	200.42	0.50921	0.246	0.0909
open field	total number of rears, 20 min test	-1.1071	10.604	-0.41800	0.963	0.917
open field	whole arena average speed, 20 min test	0.28980	0.16713	0.51074	0.246	0.0910
open field	whole arena resting time, 20 min test	-39.612	20.486	-0.55406	0.188	0.0606
open field	whole arena time spent mobile, 20 min test	39.575	20.489	0.79914	0.187	0.0609
open field	whole arena time spent vertical, 20 min test	-12.560	12.196	-1.0764	0.615	0.309
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	0.082962	1.4643	0.23573	0.990	0.955

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

In this plot, data points are the computed genotype effect % vs. C57BL/6NJ controls, for all measured categorical phenotypes in JaxKOMP-EAP

Dimensions Width: × Height: px

Plot Options Group by Procedure

Include Sexes Data Both Females Males

Significance Threshold p-Value Threshold

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Procedure	JaxKOMP-EAP Trait	Sex	Trait Effect	P-value

eye morphology	anterior chamber depth	females	1.0 %	1.0
eye morphology	anterior chamber depth	males	0.0 %	1.0
eye morphology	anterior chamber depth	both	1.0 %	1.0
eye morphology	bulging eye	females	1.0 %	1.0
eye morphology	bulging eye	males	0.0 %	1.0
eye morphology	bulging eye	both	1.0 %	1.00
eye morphology	cornea	females	4.0 %	1.0
eye morphology	cornea	males	2.0 %	1.0
eye morphology	cornea	both	3.0 %	1.00
eye morphology	cornea opacity	females	5.0 %	1.00
eye morphology	cornea opacity	males	1.0 %	1.0
eye morphology	cornea opacity	both	3.0 %	1.00
eye morphology	cornea vascularization	females	3.0 %	1.0
eye morphology	cornea vascularization	males	1.0 %	1.0
eye morphology	cornea vascularization	both	2.0 %	1.00
eye morphology	corneal deposits	females	2.0 %	1.0
eye morphology	corneal deposits	males	1.0 %	1.0
eye morphology	corneal deposits	both	1.0 %	1.00
eye morphology	corneal mineralization	females	2.0 %	1.0
eye morphology	corneal mineralization	males	1.0 %	1.0
eye morphology	corneal mineralization	both	1.0 %	1.00
eye morphology	corneal scleralization	females	3.0 %	1.00
eye morphology	corneal scleralization	males	1.0 %	1.0
eye morphology	corneal scleralization	both	2.0 %	1.00
eye morphology	corneal ulcer	females	1.0 %	1.0
eye morphology	corneal ulcer	males	1.0 %	1.0
eye morphology	corneal ulcer	both	1.0 %	1.00
eye morphology	eye closure	females	1.0 %	1.00
eye morphology	eye closure	males	0.0 %	1.0
eye morphology	eye closure	both	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	females	2.0 %	1.00
eye morphology	eye hemorrhage or blood presence	males	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	both	1.0 %	1.00
eye morphology	eyelid morphology	females	1.0 %	1.0
eye morphology	eyelid morphology	males	0.0 %	1.0
eye morphology	eyelid morphology	both	1.0 %	1.0
eye morphology	eyes (present, absent)	females	1.0 %	1.0
eye morphology	eyes (present, absent)	males	0.0 %	1.0
eye morphology	eyes (present, absent)	both	0.0 %	1.0
eye morphology	fusion between cornea and lens	females	4.0 %	1.00
eye morphology	fusion between cornea and lens	males	2.0 %	1.0
eye morphology	fusion between cornea and lens	both	3.0 %	1.00
eye morphology	iris pigmentation	females	2.0 %	1.0
eye morphology	iris pigmentation	males	1.0 %	1.0
eye morphology	iris pigmentation	both	2.0 %	1.00
eye morphology	iris transillumination	females	2.0 %	1.00
eye morphology	iris transillumination	males	1.0 %	1.0
eye morphology	iris transillumination	both	1.0 %	1.00
eye morphology	irispupil	females	11.0 %	0.275
eye morphology	irispupil	males	11.0 %	0.223
eye morphology	irispupil	both	11.0 %	0.108
eye morphology	lacrimation	females	3.0 %	1.0
eye morphology	lacrimation	males	2.0 %	1.0
eye morphology	lacrimation	both	3.0 %	1.0
eye morphology	lens	females	10.0 %	1.00
eye morphology	lens	males	9.0 %	0.496
eye morphology	lens	both	3.0 %	0.783
eye morphology	lens opacity	females	22.0 %	0.155
eye morphology	lens opacity	males	44.0 %	0.000247
eye morphology	lens opacity	both	30.0 %	0.000247
eye morphology	narrow eye opening	females	2.0 %	1.0
eye morphology	narrow eye opening	males	1.0 %	1.0
eye morphology	narrow eye opening	both	1.0 %	1.0
eye morphology	optic disc	females	4.0 %	1.00
eye morphology	optic disc	males	2.0 %	1.0
eye morphology	optic disc	both	3.0 %	1.00
eye morphology	persistence of hyaloid vascular system	females	18.0 %	0.373
eye morphology	persistence of hyaloid vascular system	males	5.0 %	1.0
eye morphology	persistence of hyaloid vascular system	both	8.0 %	0.504
eye morphology	pupil dilation	females	2.0 %	1.0
eye morphology	pupil dilation	males	1.0 %	1.0
eye morphology	pupil dilation	both	2.0 %	1.0
eye morphology	pupil light response	females	2.0 %	1.00
eye morphology	pupil light response	males	1.0 %	1.0
eye morphology	pupil light response	both	2.0 %	1.00
eye morphology	pupil position	females	11.0 %	0.301
eye morphology	pupil position	males	11.0 %	0.230
eye morphology	pupil position	both	11.0 %	0.120
eye morphology	pupil shape	females	3.0 %	1.00
eye morphology	pupil shape	males	2.0 %	1.0
eye morphology	pupil shape	both	3.0 %	1.00
eye morphology	retina	females	10.0 %	1.0
eye morphology	retina	males	22.0 %	0.0933
eye morphology	retina	both	8.0 %	0.309
eye morphology	retinal blood vessels	females	4.0 %	1.0
eye morphology	retinal blood vessels	males	2.0 %	1.0
eye morphology	retinal blood vessels	both	3.0 %	1.0
eye morphology	retinal blood vessels pattern	females	5.0 %	1.0
eye morphology	retinal blood vessels pattern	males	2.0 %	1.0
eye morphology	retinal blood vessels pattern	both	4.0 %	1.00
eye morphology	retinal blood vessels structure	females	4.0 %	1.00
eye morphology	retinal blood vessels structure	males	2.0 %	1.0
eye morphology	retinal blood vessels structure	both	3.0 %	1.00
eye morphology	retinal pigmentation	females	10.0 %	0.522
eye morphology	retinal pigmentation	males	10.0 %	0.432
eye morphology	retinal pigmentation	both	10.0 %	0.321
eye morphology	retinal structure	females	4.0 %	1.00
eye morphology	retinal structure	males	2.0 %	1.0
eye morphology	retinal structure	both	3.0 %	1.00
eye morphology	synechia	females	4.0 %	1.0
eye morphology	synechia	males	2.0 %	1.0
eye morphology	synechia	both	3.0 %	1.00
eye morphology	vitreous	females	4.0 %	1.00
eye morphology	vitreous	males	2.0 %	1.0
eye morphology	vitreous	both	3.0 %	1.00
SHIRPA	activity body position	females	1.0 %	1.0
SHIRPA	activity body position	males	2.0 %	1.0
SHIRPA	activity body position	both	1.0 %	1.00
SHIRPA	aggression	females	0.0 %	1.00
SHIRPA	aggression	males	1.0 %	1.0
SHIRPA	aggression	both	1.0 %	1.0
SHIRPA	body length	females	0.0 %	1.0
SHIRPA	body length	males	0.0 %	1.00
SHIRPA	body length	both	0.0 %	1.00
SHIRPA	body position	females	0.0 %	1.0
SHIRPA	body position	males	1.0 %	1.0
SHIRPA	body position	both	0.0 %	1.0
SHIRPA	body thickness	females	1.0 %	1.0
SHIRPA	body thickness	males	0.0 %	1.0
SHIRPA	body thickness	both	0.0 %	1.0
SHIRPA	coat color abdomen	females	3.0 %	1.00
SHIRPA	coat color abdomen	males	4.0 %	1.0
SHIRPA	coat color abdomen	both	4.0 %	1.0
SHIRPA	coat color back	females	0.0 %	1.0
SHIRPA	coat color back	males	0.0 %	1.00
SHIRPA	coat color back	both	0.0 %	1.00
SHIRPA	coat color head	females	0.0 %	1.0
SHIRPA	coat color head	males	0.0 %	1.00
SHIRPA	coat color head	both	0.0 %	1.0
SHIRPA	coat color pattern abdomen	females	1.0 %	1.0
SHIRPA	coat color pattern abdomen	males	1.0 %	1.0
SHIRPA	coat color pattern abdomen	both	1.0 %	1.0
SHIRPA	coat color pattern back	females	0.0 %	1.0
SHIRPA	coat color pattern back	males	0.0 %	1.00
SHIRPA	coat color pattern back	both	0.0 %	1.0
SHIRPA	coat color pattern head	females	0.0 %	1.0
SHIRPA	coat color pattern head	males	0.0 %	1.0
SHIRPA	coat color pattern head	both	0.0 %	1.00
SHIRPA	coat hair abdomen texture appearance	females	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	males	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	both	2.0 %	1.0
SHIRPA	coat hair back texture appearance	females	0.0 %	1.0
SHIRPA	coat hair back texture appearance	males	0.0 %	1.0
SHIRPA	coat hair back texture appearance	both	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	females	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	males	1.0 %	1.00
SHIRPA	coat hair distribution abdomen	both	1.0 %	1.00
SHIRPA	coat hair distribution back	females	0.0 %	1.0
SHIRPA	coat hair distribution back	males	0.0 %	1.0
SHIRPA	coat hair distribution back	both	0.0 %	1.0
SHIRPA	coat hair distribution head	females	1.0 %	1.00
SHIRPA	coat hair distribution head	males	1.0 %	1.0
SHIRPA	coat hair distribution head	both	1.0 %	1.0
SHIRPA	coat hair head texture appearance	females	0.0 %	1.00
SHIRPA	coat hair head texture appearance	males	0.0 %	1.0
SHIRPA	coat hair head texture appearance	both	0.0 %	1.0
SHIRPA	contact righting	females	5.0 %	1.0
SHIRPA	contact righting	males	5.0 %	1.00
SHIRPA	contact righting	both	5.0 %	1.00
SHIRPA	ear morphology	females	0.0 %	1.0
SHIRPA	ear morphology	males	0.0 %	1.0
SHIRPA	ear morphology	both	0.0 %	1.0
SHIRPA	fat distribution	females	0.0 %	1.0
SHIRPA	fat distribution	males	0.0 %	1.0
SHIRPA	fat distribution	both	0.0 %	1.00
SHIRPA	forelimb digit number	females	0.0 %	1.00
SHIRPA	forelimb digit number	males	0.0 %	1.0
SHIRPA	forelimb digit number	both	0.0 %	1.00
SHIRPA	forelimb digit position	females	0.0 %	1.0
SHIRPA	forelimb digit position	males	0.0 %	1.0
SHIRPA	forelimb digit position	both	0.0 %	1.0
SHIRPA	forelimb digit shape	females	0.0 %	1.0
SHIRPA	forelimb digit shape	males	0.0 %	1.0
SHIRPA	forelimb digit shape	both	0.0 %	1.0
SHIRPA	forelimb digit size	females	0.0 %	1.0
SHIRPA	forelimb digit size	males	0.0 %	1.0
SHIRPA	forelimb digit size	both	0.0 %	1.0
SHIRPA	forelimb footpads	females	0.0 %	1.0
SHIRPA	forelimb footpads	males	0.0 %	1.0
SHIRPA	forelimb footpads	both	0.0 %	1.0
SHIRPA	forelimb nail length	females	0.0 %	1.0
SHIRPA	forelimb nail length	males	0.0 %	1.0
SHIRPA	forelimb nail length	both	0.0 %	1.0
SHIRPA	forelimb nail number	females	0.0 %	1.0
SHIRPA	forelimb nail number	males	0.0 %	1.0
SHIRPA	forelimb nail number	both	0.0 %	1.0
SHIRPA	forelimb nail position	females	0.0 %	1.0
SHIRPA	forelimb nail position	males	0.0 %	1.0
SHIRPA	forelimb nail position	both	0.0 %	1.0
SHIRPA	forelimb nail shape	females	0.0 %	1.0
SHIRPA	forelimb nail shape	males	0.0 %	1.0
SHIRPA	forelimb nail shape	both	0.0 %	1.0
SHIRPA	forelimbs position	females	0.0 %	1.0
SHIRPA	forelimbs position	males	0.0 %	1.0
SHIRPA	forelimbs position	both	0.0 %	1.0
SHIRPA	forelimbs shape	females	0.0 %	1.0
SHIRPA	forelimbs shape	males	0.0 %	1.0
SHIRPA	forelimbs shape	both	0.0 %	1.0
SHIRPA	forelimbs size	females	0.0 %	1.0
SHIRPA	forelimbs size	males	0.0 %	1.0
SHIRPA	forelimbs size	both	0.0 %	1.0
SHIRPA	forepaw position	females	0.0 %	1.0
SHIRPA	forepaw position	males	0.0 %	1.0
SHIRPA	forepaw position	both	0.0 %	1.0
SHIRPA	forepaw shape	females	0.0 %	1.0
SHIRPA	forepaw shape	males	0.0 %	1.0
SHIRPA	forepaw shape	both	0.0 %	1.0
SHIRPA	forepaw size	females	0.0 %	1.0
SHIRPA	forepaw size	males	0.0 %	1.0
SHIRPA	forepaw size	both	0.0 %	1.0
SHIRPA	gait (fluidity)	females	0.0 %	1.0
SHIRPA	gait (fluidity)	males	0.0 %	1.00
SHIRPA	gait (fluidity)	both	0.0 %	1.00
SHIRPA	genitalia morphology	females	0.0 %	1.00
SHIRPA	genitalia morphology	males	0.0 %	1.0
SHIRPA	genitalia morphology	both	0.0 %	1.00
SHIRPA	genitalia presence	females	0.0 %	1.0
SHIRPA	genitalia presence	males	0.0 %	1.0
SHIRPA	genitalia presence	both	0.0 %	1.0
SHIRPA	genitalia size	females	0.0 %	1.0
SHIRPA	genitalia size	males	0.0 %	1.0
SHIRPA	genitalia size	both	0.0 %	1.0
SHIRPA	head bobbing	females	0.0 %	1.0
SHIRPA	head bobbing	males	0.0 %	1.0
SHIRPA	head bobbing	both	0.0 %	1.0
SHIRPA	head morphology	females	0.0 %	1.0
SHIRPA	head morphology	males	0.0 %	1.00
SHIRPA	head morphology	both	0.0 %	1.0
SHIRPA	head size	females	0.0 %	1.0
SHIRPA	head size	males	0.0 %	1.0
SHIRPA	head size	both	0.0 %	1.00
SHIRPA	hindlimb digit number	females	1.0 %	1.00
SHIRPA	hindlimb digit number	males	0.0 %	1.0
SHIRPA	hindlimb digit number	both	0.0 %	1.00
SHIRPA	hindlimb digit position	females	0.0 %	1.0
SHIRPA	hindlimb digit position	males	0.0 %	1.0
SHIRPA	hindlimb digit position	both	0.0 %	1.0
SHIRPA	hindlimb digit shape	females	0.0 %	1.0
SHIRPA	hindlimb digit shape	males	0.0 %	1.0
SHIRPA	hindlimb digit shape	both	0.0 %	1.0
SHIRPA	hindlimb digit size	females	0.0 %	1.00
SHIRPA	hindlimb digit size	males	0.0 %	1.0
SHIRPA	hindlimb digit size	both	0.0 %	1.00
SHIRPA	hindlimb nail length	females	0.0 %	1.0
SHIRPA	hindlimb nail length	males	0.0 %	1.0
SHIRPA	hindlimb nail length	both	0.0 %	1.00
SHIRPA	hindlimb nail number	females	0.0 %	1.0
SHIRPA	hindlimb nail number	males	1.0 %	1.0
SHIRPA	hindlimb nail number	both	0.0 %	1.00
SHIRPA	hindlimb nail position	females	0.0 %	1.0
SHIRPA	hindlimb nail position	males	0.0 %	1.0
SHIRPA	hindlimb nail position	both	0.0 %	1.0
SHIRPA	hindlimb nail shape	females	0.0 %	1.0
SHIRPA	hindlimb nail shape	males	0.0 %	1.0
SHIRPA	hindlimb nail shape	both	0.0 %	1.0
SHIRPA	hindlimbs footpads	females	0.0 %	1.0
SHIRPA	hindlimbs footpads	males	0.0 %	1.0
SHIRPA	hindlimbs footpads	both	0.0 %	1.0
SHIRPA	hindlimbs position	females	0.0 %	1.0
SHIRPA	hindlimbs position	males	0.0 %	1.0
SHIRPA	hindlimbs position	both	0.0 %	1.0
SHIRPA	hindlimbs shape	females	0.0 %	1.0
SHIRPA	hindlimbs shape	males	0.0 %	1.0
SHIRPA	hindlimbs shape	both	0.0 %	1.0
SHIRPA	hindlimbs size	females	0.0 %	1.0
SHIRPA	hindlimbs size	males	0.0 %	1.0
SHIRPA	hindlimbs size	both	0.0 %	1.0
SHIRPA	hindpaw position	females	0.0 %	1.0
SHIRPA	hindpaw position	males	0.0 %	1.0
SHIRPA	hindpaw position	both	0.0 %	1.0
SHIRPA	hindpaw shape	females	0.0 %	1.0
SHIRPA	hindpaw shape	males	0.0 %	1.0
SHIRPA	hindpaw shape	both	0.0 %	1.0
SHIRPA	hindpaw size	females	0.0 %	1.0
SHIRPA	hindpaw size	males	0.0 %	1.0
SHIRPA	hindpaw size	both	0.0 %	1.0
SHIRPA	limb grasp	females	4.0 %	0.524
SHIRPA	limb grasp	males	6.0 %	1.0
SHIRPA	limb grasp	both	1.0 %	1.0
SHIRPA	lower lip morphology	females	0.0 %	1.0
SHIRPA	lower lip morphology	males	0.0 %	1.0
SHIRPA	lower lip morphology	both	0.0 %	1.0
SHIRPA	lower teeth appearance	females	0.0 %	1.0
SHIRPA	lower teeth appearance	males	0.0 %	1.00
SHIRPA	lower teeth appearance	both	0.0 %	1.00
SHIRPA	mouth morphology	females	0.0 %	1.0
SHIRPA	mouth morphology	males	0.0 %	1.00
SHIRPA	mouth morphology	both	0.0 %	1.00
SHIRPA	salivation	females	0.0 %	1.0
SHIRPA	salivation	males	0.0 %	1.0
SHIRPA	salivation	both	0.0 %	1.0
SHIRPA	skin color back paws	females	0.0 %	1.0
SHIRPA	skin color back paws	males	0.0 %	1.0
SHIRPA	skin color back paws	both	0.0 %	1.0
SHIRPA	skin color ear	females	0.0 %	1.0
SHIRPA	skin color ear	males	0.0 %	1.0
SHIRPA	skin color ear	both	0.0 %	1.0
SHIRPA	skin color front paws	females	0.0 %	1.0
SHIRPA	skin color front paws	males	0.0 %	1.0
SHIRPA	skin color front paws	both	0.0 %	1.0
SHIRPA	skin color snout	females	0.0 %	1.0
SHIRPA	skin color snout	males	0.0 %	1.0
SHIRPA	skin color snout	both	0.0 %	1.0
SHIRPA	skin color tail	females	0.0 %	1.0
SHIRPA	skin color tail	males	0.0 %	1.0
SHIRPA	skin color tail	both	0.0 %	1.0
SHIRPA	skin color whole body	females	0.0 %	1.0
SHIRPA	skin color whole body	males	0.0 %	1.0
SHIRPA	skin color whole body	both	0.0 %	1.0
SHIRPA	skin texture back paw	females	0.0 %	1.0
SHIRPA	skin texture back paw	males	0.0 %	1.0
SHIRPA	skin texture back paw	both	0.0 %	1.0
SHIRPA	skin texture ear	females	0.0 %	1.0
SHIRPA	skin texture ear	males	0.0 %	1.0
SHIRPA	skin texture ear	both	0.0 %	1.0
SHIRPA	skin texture front paws	females	0.0 %	1.0
SHIRPA	skin texture front paws	males	0.0 %	1.0
SHIRPA	skin texture front paws	both	0.0 %	1.0
SHIRPA	skin texture snout	females	0.0 %	1.0
SHIRPA	skin texture snout	males	0.0 %	1.0
SHIRPA	skin texture snout	both	0.0 %	1.0
SHIRPA	skin texture tail	females	0.0 %	1.0
SHIRPA	skin texture tail	males	0.0 %	1.0
SHIRPA	skin texture tail	both	0.0 %	1.0
SHIRPA	skin texture whole body	females	0.0 %	1.0
SHIRPA	skin texture whole body	males	0.0 %	1.00
SHIRPA	skin texture whole body	both	0.0 %	1.00
SHIRPA	snout size	females	0.0 %	1.0
SHIRPA	snout size	males	1.0 %	1.0
SHIRPA	snout size	both	0.0 %	1.0
SHIRPA	startle response	females	0.0 %	1.00
SHIRPA	startle response	males	0.0 %	1.00
SHIRPA	startle response	both	0.0 %	1.00
SHIRPA	tail curvature	females	0.0 %	1.00
SHIRPA	tail curvature	males	0.0 %	1.0
SHIRPA	tail curvature	both	0.0 %	1.0
SHIRPA	tail elevation	females	1.0 %	1.00
SHIRPA	tail elevation	males	23.0 %	0.00946
SHIRPA	tail elevation	both	11.0 %	0.0329
SHIRPA	tail length	females	0.0 %	1.0
SHIRPA	tail length	males	0.0 %	1.0
SHIRPA	tail length	both	0.0 %	1.00
SHIRPA	tail morphology	females	0.0 %	1.00
SHIRPA	tail morphology	males	0.0 %	1.0
SHIRPA	tail morphology	both	0.0 %	1.00
SHIRPA	tail presence	females	0.0 %	1.0
SHIRPA	tail presence	males	0.0 %	1.0
SHIRPA	tail presence	both	0.0 %	1.0
SHIRPA	tail shape	females	0.0 %	1.0
SHIRPA	tail shape	males	0.0 %	1.0
SHIRPA	tail shape	both	0.0 %	1.00
SHIRPA	tail thickness	females	0.0 %	1.0
SHIRPA	tail thickness	males	0.0 %	1.0
SHIRPA	tail thickness	both	0.0 %	1.0
SHIRPA	teeth presence	females	0.0 %	1.0
SHIRPA	teeth presence	males	0.0 %	1.00
SHIRPA	teeth presence	both	0.0 %	1.00
SHIRPA	transfer arousal	females	1.0 %	1.0
SHIRPA	transfer arousal	males	2.0 %	1.00
SHIRPA	transfer arousal	both	1.0 %	1.0
SHIRPA	tremor	females	0.0 %	1.0
SHIRPA	tremor	males	0.0 %	1.0
SHIRPA	tremor	both	0.0 %	1.00
SHIRPA	trunk curl	females	0.0 %	1.00
SHIRPA	trunk curl	males	0.0 %	1.0
SHIRPA	trunk curl	both	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	females	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	males	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	both	0.0 %	1.00
SHIRPA	upper lip morphology	females	0.0 %	1.0
SHIRPA	upper lip morphology	males	0.0 %	1.0
SHIRPA	upper lip morphology	both	0.0 %	1.0
SHIRPA	upper teeth appearance	females	0.0 %	1.0
SHIRPA	upper teeth appearance	males	0.0 %	1.0
SHIRPA	upper teeth appearance	both	0.0 %	1.00
SHIRPA	vibrissae appearance	females	2.0 %	1.0
SHIRPA	vibrissae appearance	males	1.0 %	1.0
SHIRPA	vibrissae appearance	both	1.0 %	1.0
SHIRPA	vibrissae presence	females	2.0 %	1.00
SHIRPA	vibrissae presence	males	1.0 %	1.0
SHIRPA	vibrissae presence	both	2.0 %	1.0
SHIRPA	vocalization	females	2.0 %	1.00
SHIRPA	vocalization	males	2.0 %	1.0
SHIRPA	vocalization	both	2.0 %	1.00
XRay	alive (yes, no)	females	89.0 %	0.0202
XRay	alive (yes, no)	both	92.0 %	0.0107
XRay	brachydactyly	females	0.0 %	1.0
XRay	brachydactyly	both	0.0 %	1.0
XRay	cervical processes	females	0.0 %	1.0
XRay	cervical processes	both	0.0 %	1.0
XRay	clavicle	females	0.0 %	1.0
XRay	clavicle	both	0.0 %	1.0
XRay	digit integrity	females	0.0 %	1.0
XRay	digit integrity	both	0.0 %	1.0
XRay	femur	females	0.0 %	1.0
XRay	femur	both	0.0 %	1.0
XRay	fibula	females	0.0 %	1.0
XRay	fibula	both	0.0 %	1.0
XRay	fusion of ribs	females	0.0 %	1.0
XRay	fusion of ribs	both	0.0 %	1.0
XRay	fusion of vertebrae	females	0.0 %	1.0
XRay	fusion of vertebrae	both	0.0 %	1.0
XRay	humerus	females	0.0 %	1.0
XRay	humerus	both	0.0 %	1.0
XRay	joints	females	11.0 %	1.0
XRay	joints	both	13.0 %	1.0
XRay	kyphosis	females	0.0 %	1.0
XRay	kyphosis	both	0.0 %	1.0
XRay	lordosis	females	0.0 %	1.0
XRay	lordosis	both	0.0 %	1.0
XRay	mandibles	females	0.0 %	1.0
XRay	mandibles	both	0.0 %	1.0
XRay	maxilla	females	0.0 %	1.0
XRay	maxilla	both	0.0 %	1.0
XRay	pelvis	females	3.0 %	1.0
XRay	pelvis	both	4.0 %	1.00
XRay	polysyndactylism	females	0.0 %	1.0
XRay	polysyndactylism	both	0.0 %	1.0
XRay	processes on vertebrae	females	0.0 %	1.0
XRay	processes on vertebrae	both	0.0 %	1.0
XRay	radius	females	0.0 %	1.0
XRay	radius	both	0.0 %	1.0
XRay	scapulae	females	0.0 %	1.0
XRay	scapulae	both	0.0 %	1.0
XRay	scoliosis	females	0.0 %	1.0
XRay	scoliosis	both	0.0 %	1.0
XRay	shape of ribs	females	0.0 %	1.0
XRay	shape of ribs	both	0.0 %	1.0
XRay	shape of spine	females	0.0 %	1.0
XRay	shape of spine	both	0.0 %	1.0
XRay	shape of vertebrae	females	0.0 %	1.0
XRay	shape of vertebrae	both	1.0 %	1.0
XRay	skull shape	females	0.0 %	1.0
XRay	skull shape	both	0.0 %	1.0
XRay	syndactylism	females	0.0 %	1.0
XRay	syndactylism	both	0.0 %	1.0
XRay	teeth	females	0.0 %	1.0
XRay	teeth	both	0.0 %	1.0
XRay	tibia	females	0.0 %	1.0
XRay	tibia	both	0.0 %	1.0
XRay	transitional vertebrae	females	0.0 %	1.0
XRay	transitional vertebrae	both	0.0 %	1.0
XRay	ulna	females	0.0 %	1.0
XRay	ulna	both	0.0 %	1.0
XRay	zygomatic bone	females	0.0 %	1.0
XRay	zygomatic bone	both	0.0 %	1.0

GENOTYPE CORRELATION PLOT

Correlate Osbpl10^em1(IMPC)J -/- with genotype: